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<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G328</accession>
    <name>A0A8T0G328_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">DNA polymerase eta</fullName>
            <ecNumber evidence="5">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_12G002200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 18">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA polymerase type-Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="5"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G328"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005657">
        <property type="term" value="C:replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035861">
        <property type="term" value="C:site of double-strand break"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042276">
        <property type="term" value="P:error-prone translesion synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009411">
        <property type="term" value="P:response to UV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.270:FF:000029">
        <property type="entry name" value="DNA polymerase eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1170.60:FF:000003">
        <property type="entry name" value="DNA polymerase eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000014">
        <property type="entry name" value="Polymerase (DNA directed), eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.100">
        <property type="entry name" value="DNA polymerase, Y-family, little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036775">
        <property type="entry name" value="DNA_pol_Y-fam_lit_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052230">
        <property type="entry name" value="DNA_polymerase_eta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001126">
        <property type="entry name" value="UmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45873:SF1">
        <property type="entry name" value="DNA POLYMERASE ETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00817">
        <property type="entry name" value="IMS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21704">
        <property type="entry name" value="POLH-Rev1_HhH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036603">
        <property type="entry name" value="DPol_eta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100879">
        <property type="entry name" value="Lesion bypass DNA polymerase (Y-family), little finger domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50173">
        <property type="entry name" value="UMUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UmuC" evidence="15">
        <location>
            <begin position="14"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0553321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="753" mass="82505" checksum="E08D647A5BD94F00" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4P9</accession>
    <name>A0A8T0G4P9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G056000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Endomembrane system</location>
            <topology evidence="7">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4P9"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01868">
        <property type="entry name" value="Rab11_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000274">
        <property type="entry name" value="ras-related protein RABA5a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050209">
        <property type="entry name" value="Rab_GTPases_membrane_traffic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47979">
        <property type="entry name" value="DRAB11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0636">Prenylation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00037868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="24486" checksum="E6812E4301CC187D" modified="2022-10-12" version="1">MANGYNEYENKIDYVFKVVLIGDSAVGKSQLLARFSRNEFSLESKATIGVEFQTRTIVVDHKTIKAQIWDTAGQERYRAVTSAYYRGAVGAMLVYDITKQQSFDHAQRWLDELRAHADANIVIMLIGNKSDLGNLRQVETETAKEFAQKEGLSFLETSAMESTNVETAFYTVLSEIYKIVSKKALIADESQGTSALLPGTKINLTDKDDVVATKKGGCCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5W0</accession>
    <name>A0A8T0G5W0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G040500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5W0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035801532" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5813" checksum="3859EB922251063B" modified="2022-10-12" version="1">MWLMMLLRYLTVQSHSTLTAYIADSKVLSASFELLKLFSGVPGCNRVFFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G676</accession>
    <name>A0A8T0G676_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G005100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G676"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11770" checksum="FF231C46B8CCA9F1" modified="2022-10-12" version="1">MSTWKNTKLLQRRKETCRGSVCTEIHTTVREGALIAVTLPPRPPASAKTKAVDSLPRVVQCPLGQKRHSFHGFQVLQVLLSTSICLILGGSSTSWSIPGTQKPMSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6U8</accession>
    <name>A0A8T0G6U8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G039200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6U8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805562" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5640" checksum="6624030BDB0A971A" modified="2022-10-12" version="1">MAMVVPRVQSFSSFLTILFLCLAMDLQAVYAVCRRVGEIFKRRGRDASVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6Y6</accession>
    <name>A0A8T0G6Y6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G073400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6Y6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07981">
        <property type="entry name" value="HFD_TAF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000011">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037794">
        <property type="entry name" value="TAF12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003228">
        <property type="entry name" value="TFIID_TAF12_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12264:SF21">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03847">
        <property type="entry name" value="TFIID_20kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription initiation factor TFIID subunit 12" evidence="7">
        <location>
            <begin position="357"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="225"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="481"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="225"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="495"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="508" mass="54072" checksum="2798E9A29368D0D6" modified="2022-10-12" version="1">MVQEEEIRAPTAGPTGVPGATLNRSLSGQRLPQYQQTPGIAMAGRPPTAGVPTPHYNPQFMATSAAVSSAGTTASPMMMAQRPGQMPQQRPAVAGQGTQVRGGSYLQQAQQYPPTQFVHHMSSAPMTNMNAARPGVQGSIAPATTTPHYGNMQNLAVAQQHNMQARQKPTQGQTAGTQYVGVTAGQQQALGVARQGASITSQQQQQALQQQQQQQQQMNAQRLVPQQQQQAMARQTQSQQMLQNQGSTMLARGTSTGAQMQGVASAGQPQQVWQGKPAQYQQQPQQQQQQQQQQQQQQQQQQTPQPARPPMVTASLATSQARPATPGAAQANSALPSSAPATAANTEPVNATGSILGKRSIQDLLAQIDPRERLDPDVEEVFLEIADDFIENVASFSCKIAQHRKSKILEAKDVLLHLDKAYNITVPGFGGDEYRSYKRPTVSETHKQRLAVVRKSAAAGQAAAEIKASNLLAAAPATNVSTPVKSGLGTGPTASPTPSPGMPRIPRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7B9</accession>
    <name>A0A8T0G7B9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G114900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7B9"/>
    <dbReference type="OrthoDB" id="10498206at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19553" checksum="B585478840DFB634" modified="2022-10-12" version="1">MLRTHSLRGHGAYSSNAQTVPVMRVTLAEPSVDQQAAKDTTGLSGGVLAGIVVGSVLGGVLLIVLIGLLIRCLCQRRKVSTDQAKVGTINSETKTASSSVWNCFRNRNTRGRRVPPPIFGSDKLDPDDISDTSFVLPELGGPNPHNKFDGMEWVDIKGLDDDHLQDISTDLRKYSQGQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAE3</accession>
    <name>A0A8T0GAE3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G076900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAE3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11385" checksum="6308B00813F87689" modified="2022-10-12" version="1">MRPFAYISKHRLVLDSHSVRQYNANVLSRCCTEIVPYCVSSGLRVKCLLKTPPYYDLPGLLFLLCTRWLVRAESSACQSFSELGGELLHEKASELKKWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAW5</accession>
    <name>A0A8T0GAW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Photosystem I reaction center subunit III</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">PSI-F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G041900</name>
        <name evidence="7" type="ORF">KC19_11G042000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Participates in efficiency of electron transfer from plastocyanin to P700 (or cytochrome c553 in algae and cyanobacteria). This plastocyanin-docking protein contributes to the specific association of plastocyanin to PSI.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PsaF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAW5"/>
    <dbReference type="OrthoDB" id="1920411at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009538">
        <property type="term" value="C:photosystem I reaction center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.110:FF:000001">
        <property type="entry name" value="Photosystem I reaction center subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.110">
        <property type="entry name" value="Photosystem I PsaF, reaction centre subunit III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003666">
        <property type="entry name" value="PSI_PsaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036577">
        <property type="entry name" value="PSI_PsaF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34939:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT III, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02507">
        <property type="entry name" value="PSI_PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81536">
        <property type="entry name" value="Subunit III of photosystem I reaction centre, PsaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU368107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="244" mass="25902" checksum="3A6E6ACD7CF016DB" modified="2022-10-12" version="1">MASVTMASIAPAGLVAPLARDVSSKGVTSGARSVFVNSRARTVCSASSSSADETIVQTAGKFATALALAAIVGGDMVVPEARADVAGLTPCKESKGFAKREKQEIKKLESRLKLYAPDSAPALAINATIEKTRRRFAFYGNEGLLCGTDGLPHLIVDGDQAHLGEFVYPGLVFLYIAGWIGWVGRAYLIDVRMSKKPTEKEIIIDVPLALKIMSKGLTWPIAALGELRNGKLVEKSSNITVSPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD15</accession>
    <name>A0A8T0GD15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G038100</name>
        <name evidence="4" type="ORF">KC19_11G038200</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small hydrophilic plant seed protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD15"/>
    <dbReference type="OrthoDB" id="540492at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038956">
        <property type="entry name" value="LEA_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022377">
        <property type="entry name" value="Sm_Hydphi_plant_seed_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000389">
        <property type="entry name" value="Small_hydrophilic_seed_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671">
        <property type="entry name" value="EM-LIKE PROTEIN GEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671:SF19">
        <property type="entry name" value="EMBRYONIC ABUNDANT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00477">
        <property type="entry name" value="LEA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00431">
        <property type="entry name" value="SMALL_HYDR_PLANT_SEED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9138" checksum="B09CA4B5032C2355" modified="2022-10-12" version="1">MTGKDTQDLDARAAAGETVVPGGTGGKSLEAQQHLAEGRSRGGQARAEQLGHDGYVEMGKKGGSATSEMSGGEAADAAGREIDESKFTNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD31</accession>
    <name>A0A8T0GD31_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G068500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="18230" checksum="760059D902DB4AD9" modified="2022-10-12" version="1">MDQDRGLLLAWMALVYIRRGAKHYNDPMVKLPDLPHLSLLLSKSSVYDWTEDCRDEVFKLGEASGFPFTRFLTELELPSNVHGYCSAAPITVDTTSDEVFTSSASTASLVSGDGVRSPVNSDSYSAVGAHIGEAREVRGVENYQGEVDGVAASTGAGVGSGVGAVVYCCCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG64</accession>
    <name>A0A8T0GG64_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G171300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052607">
        <property type="entry name" value="CEP104-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048738">
        <property type="entry name" value="CEP104_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371:SF0">
        <property type="entry name" value="CENTROSOMAL PROTEIN OF 104 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13371">
        <property type="entry name" value="GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21040">
        <property type="entry name" value="CEP104-like_TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21039">
        <property type="entry name" value="CEP104_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TOG" evidence="2">
        <location>
            <begin position="390"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="672"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="680"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="923" mass="102223" checksum="C460D213A6BF8ED5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGA1</accession>
    <name>A0A8T0GGA1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box associated beta-propeller type 3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G019800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013187">
        <property type="entry name" value="F-box-assoc_dom_typ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08268">
        <property type="entry name" value="FBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box associated beta-propeller type 3" evidence="1">
        <location>
            <begin position="205"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="480" mass="55290" checksum="93BFAD1B11A7912F" modified="2022-10-12" version="1">MCLSEVPISSPHPQIRNAMWFCGAREDNQLGSVEFHHGNATRACPGMTSGCCDGLGYMGNVPYIFVKICEWWPKHWSWLFVILRCAFERFSVGKLWELRPQLRPGWLAWPKQPLKKKFRNLRSCVMRALRNCIERNTFLPSRDEFNLECVTLRAPHFFIKDGVWRCAGYDSSLQKWRHLPPLTFLPAYCKPDGDLFKEYLVCIKDGIVCMNVSKTSQDKFIVFNPLTGKWKELPPLNHRRNPVLMHLVVDALTKSYQVIVAGSSRSGDGRLSRITEVFDSRIGKWTRTGDLPGPDYALNDYQSGVYVDGYLYCIAFLDQEAGRGILRYNLNKSTWSNNWKYLIPFSTNSTILQLVESWGELYLFSEQVNENNVEHWIDRVEWDTDIERGVSWSLNSVMRSEKMGGRSLEVYPEYTCLPYSKHQLCVFNTIDHSGVVYDVRNHRQSEVLQAPPADQGFSGESFVSLNPLSFTIELSSKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIC1</accession>
    <name>A0A8T0GIC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G136200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIC1"/>
    <dbReference type="OrthoDB" id="546249at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0557508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="602" mass="66745" checksum="E1493D4BB56ABE29" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIE7</accession>
    <name>A0A8T0GIE7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G022100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035888937" evidence="1">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="5884" checksum="06FB85A533D4762F" modified="2022-10-12" version="1">MSTPLTFLFLQLLHCLDCCEHHSSKGEAYVVYVNWPGCAGSLKTCALTSVFSAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJV8</accession>
    <name>A0A8T0GJV8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="7">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_10G094800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Secreted</location>
            <location evidence="7">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Secreted</location>
            <location evidence="7">Extracellular space</location>
            <location evidence="7">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="7"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0052">Apoplast</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035959548" description="Xyloglucan endotransglucosylase/hydrolase" evidence="7">
        <location>
            <begin position="25"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="8">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0559300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="33296" checksum="0A8078378595670D" modified="2022-10-12" version="1">MASFGGCLTIATLVLLSMVAGSQGNNALANQFTTWTPKNCEFTPDGRGVDLIVRNQSMPYASMTSKNWFMYGGIGAWIKLIPNNSAGTVTTFYLSSTGPKHCEFDFEFLGNVSGQPYVLHSNIFVDGIGGREQQIFLWFDPTTDYHYYNFQWNKDLLVFYVDNTPIRMFRNLEGIAPGFLYPKACPMALYLSVWDGSKWATQNGRVKIDWTAVPFVASYKNFRLNGCLANQGDKPAIAACQNTKWAAPGPRSQTIGGTRTRKLREIKNNYVRYNYCDDLKRWNYTIPGECNYNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM84</accession>
    <name>A0A8T0GM84_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G058500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM84"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00122">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011124">
        <property type="entry name" value="Znf_CW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396:SF0">
        <property type="entry name" value="METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396">
        <property type="entry name" value="METHYL-CPG BINDING PROTEIN, MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01429">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07496">
        <property type="entry name" value="zf-CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00391">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51050">
        <property type="entry name" value="ZF_CW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CW-type" evidence="11">
        <location>
            <begin position="111"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="MBD" evidence="10">
        <location>
            <begin position="185"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="247"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="49"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="342"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0558848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="354" mass="39013" checksum="D0CB228CB2135809" modified="2022-10-12" version="1">MVVRDDGVEAREAAVREPDSVASGDVRPDSRQQVNSEDTLKGLSEVGPVDERVLSSLRVKESGEGDGSQGTSEAEKKSKVAISHEVKDEPSSDTDMEKEGEDAAQERSESAPDAPRWTATGVETYAIQCNVCFKWRVVPSKERYEAIGEQILQKPFECVHAQEWRHNASCEEPADIEENEPTVLWAIDKHNLPRSPKGFYRKVVLRAENAKKFADIYYKAPCGKTLRSMVQVQKYLDEHPHLGVDISQFSFTSPKGKTDETQSRGVSTKRPLKNEAHPSKKLKGSPDPKTPGHGQPPRPKTPSIGKGSIPKYSASKLNDVRRDTPVKGKLHGSKGAPHPMAVKREKFGADGVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPN3</accession>
    <name>A0A8T0GPN3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G073500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="101"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="49024" checksum="A197C8A662426F95" modified="2022-10-12" version="1">METEESEGCSAGTRNVAKEADHTTRASRFVSAVEQQIERSKAHWSTLADGPSGACMAEDEDGEGDCNAEESNVREFMQLQRHPTWGTFFSIFNGEDYNAELVVGEKFAEGGQAELFHAKVIWSHPESSEWAEEKGIEFVVKVFKKGTFLRDLKSQLPHGLLQHHVERMKILEPPTPKLMPRYFCKVHRGILLENGQFAFLMEKEHFDLRSLIEGKMELKSDGDSGPFSKEDGEVMMYHIALGLEWLHNHDIIHRDLKASNVLVREYKRRWLKWHCFVADYECSIGVVGTGFFRAPEILQACKERMASQRPKVFTRAGDVYAYGMTCYEVLTGKLPFENHPLTDNKSLLTDLVINQDLRPEIPQYVEGWASELLNWSWQCDPSARPKIEEILDLLCRNSESIKIREKKLKEKFGDNFRYIPMPLSGIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPS0</accession>
    <name>A0A8T0GPS0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G162800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35279">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35279:SF4">
        <property type="entry name" value="GLYCOSYL HYDROLASE FAMILY 32 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="48687" checksum="9F412B359D618100" modified="2022-10-12" version="1">MSALSLVCNLASLNFGITSLGYTHKSLCAVQSSGSFSSLAHHPQRLLPQPFKVTKEGRAQRRSSIVIKYSAMDTDIQADRRFSGRVLGPAPADFDWWDKKLLSGAVVVPEIGKPGYRMYYYGRGTDEWAKGVTPFNASLPTGRNGMAVSEDGLQFERYKGHLSGGAIMDPSEEYDTFDAVHLGVSDVFYDQAEDIWRMFYFGGGYDESPLPTNPEKLFRGLRLRPGVATSKDGLAFEDREGPILELGEEGAWDRVGVSWPRVLRPEGDGNGKWLLTYHTRETGGRNNFGFFSAGVATSTDGKHWQKVSKILSTGEPGTWDEGGVSVRHVLRVNGKYVMFYEGSDYKFQFAIGLATSDDGLVWEKDTGVGPEPGGPILKARVGENVWDNVIVGTPYVLAMDDGSFRMYYLGVGKLEGDEASKQGIGLAVSDGPNYRSWKRFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPZ8</accession>
    <name>A0A8T0GPZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G076900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000025">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF19">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="48"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0559072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="33439" checksum="F07A7789CAB2A1FC" modified="2022-10-12" version="1">MLERDVLENSPGVQWEHIAGLTEAKRLLEEAVALPLWMSEYFQGIRRPWKGVLMFGPPGTGKTLLAKAVATECGTTFFNVSSATLASKWRGESERMVRVLFDLARAYAPSTIFIDKIDSLCNARGGSGEHESSRRVKSELLVQVDGVNNTSDDGDKKIVMVLAATNFPWDIDEALRRRLEKRIYIPLPLEEGRRELIRINLKDIEVAKDVDINALAKRTEGYSGDDLTNICRDASMNGMRRKIAGKTPEEIKTMTKDQMYEPVAMHDFDEALCKISRSVSTADIERHEKWLNEFGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ04</accession>
    <name>A0A8T0GQ04_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G037100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ04"/>
    <dbReference type="OrthoDB" id="360653at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13225" checksum="2EFFBF0A902D6DBF" modified="2022-10-12" version="1">MEVDDGTDGSDGKSVSTVVEIADKDVEDVDGDDLNEDGESEKPNTSRRGTHELRTLCLKIIATVLAKLDDFAHNPVYWDIFFQSISPSIQKFAPENHSSIAPGAVFSCLLDMNQRALRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRR4</accession>
    <name>A0A8T0GRR4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyrrolo-quinoline quinone repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G039400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial PQQ dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.10">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32303:SF10">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32303">
        <property type="entry name" value="QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="4">
        <location>
            <begin position="91"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="4">
        <location>
            <begin position="396"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="570" mass="61167" checksum="3571F2CA83EE6EE1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUP1</accession>
    <name>A0A8T0GUP1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G167400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="259" mass="29775" checksum="08F8F346A304C08F" modified="2022-10-12" version="1">MATVELSTAITEVEVKEANAYKDAIVELKAITEVEGKETKAYKDAIVKQNDLKKWEPPVDQFTLIKNVSLIEKNPVYSVALKEWDRTRARFEEKVDRREKNITDLKNHVFNIVGFFSVFQGVVLTTVTQLNSDKYDTCGIIWFPIALSTVAALGSAYAVWHKFSNLRAMEDFVRSDRQSRQAVENWAQKLRESGKENFFFYKDTEDPKELPSATFYWNRFGVIVGLFFFTILFVLSYLAILCDFLDILNLKGGFGAVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVC5</accession>
    <name>A0A8T0GVC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G152600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVC5"/>
    <dbReference type="OrthoDB" id="1919377at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008390">
        <property type="entry name" value="AWPM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294:SF5">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05512">
        <property type="entry name" value="AWPM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="18147" checksum="B4C9DB3DAE6D5E52" modified="2022-10-12" version="1">MAFGIGRGMTAPLAVLNFILYFISACLAGSILNHNLDGGVGSDDPGLIGNVVTSTFLIIALIASVVGMASCLAGAHHLRLWRTETLAAAAATSVIAWLLTLLAMGIACKEIHTGGYRTKRLKTLEAFMIILAFLELLYLLTTHAGSVTGEGYTNTPGNRAVKNPNYGTPAATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVE8</accession>
    <name>A0A8T0GVE8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G119400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="225"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="520" mass="59362" checksum="0688222A4C49C474" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW32</accession>
    <name>A0A8T0GW32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G071500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035835891" description="Secreted protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="9073" checksum="04E3106AEBF6E3B0" modified="2022-10-12" version="1">MSAFPGMRCSHFAGRFSALSLVPIVLILMKDVSGAGLDRCAGEYASKFAGEFAGACDFGHHSVRNPYLQTWCKYRMLFNVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWF9</accession>
    <name>A0A8T0GWF9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="11">HMG-CoA reductase</shortName>
            <ecNumber evidence="11">1.1.1.34</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_9G178800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(R)-mevalonate + 2 NADP(+) + CoA = (3S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:15989"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.34"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Metabolic intermediate biosynthesis; (R)-mevalonate biosynthesis; (R)-mevalonate from acetyl-CoA: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Endoplasmic reticulum membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.34" evidence="11"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00643">
        <property type="entry name" value="HMG-CoA_reductase_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3270.10:FF:000002">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.420:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.770.10:FF:000001">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl coenzyme A reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="entry name" value="3-hydroxy-3-methylglutaryl-coenzyme A Reductase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3270.10">
        <property type="entry name" value="HMGR, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.420">
        <property type="entry name" value="Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004554">
        <property type="entry name" value="HMG_CoA_Rdtase_eu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023282">
        <property type="entry name" value="HMG_CoA_Rdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00533">
        <property type="entry name" value="HMG_CoA_R_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572:SF24">
        <property type="entry name" value="3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="NAD-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="Substrate-binding domain of HMG-CoA reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0521">NADP</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0562877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="584" mass="62805" checksum="FB86976CC3D2C685" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWX8</accession>
    <name>A0A8T0GWX8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G001500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWX8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15565">
        <property type="entry name" value="PHD2_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058939">
        <property type="entry name" value="Mtase_EDM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055198">
        <property type="entry name" value="NSD_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235:SF3">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26055">
        <property type="entry name" value="Mtase_EDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22908">
        <property type="entry name" value="PHD_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="420"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="482"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="5">
        <location>
            <begin position="553"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="624"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="973"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="161"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="974"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1056"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1078"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1119"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="1191"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0563057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1230" mass="133896" checksum="739E37AEBB89EA1B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYK0</accession>
    <name>A0A8T0GYK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G021300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYK0"/>
    <dbReference type="OrthoDB" id="62at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0195">Cyclin</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="4">
        <location>
            <begin position="180"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0563319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="340" mass="37153" checksum="1EF42486BB76D432" modified="2022-10-12" version="1">MTLLRPLEKMTAQLGGEAGGVLVKDLLCGEALSPNTHCPARHAGLHHDDHNNAPLWLGTSRLSPFNPMRGSSFPSKYGDEYSPRSGYPPKIFCADDVAVAVFTARSDPPLRRKPVALVADSISIPWPTFAELGEAMCVLQEREAQMAYRLTARYVDALMESDLPKSPFSEVCSLRRDGVFHIFKLVEALRLRILIAAHAVAYLDRFLSTSMVSTVIESTTAMQFQYIAAACVSIAAKMDATAAPSLASLSRFSGEGTMMSEAKLREMEAVVLQVLGWKLLGVTTSDFVDNMIAHLPLSGVPSALVQAARRRADEFIHFTLTGFTIIPISLSRFKILPLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0M9</accession>
    <name>A0A8T0H0M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G098800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the plant self-incompatibility (S1) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060320">
        <property type="term" value="P:rejection of self pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010264">
        <property type="entry name" value="Self-incomp_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232:SF18">
        <property type="entry name" value="S-PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05938">
        <property type="entry name" value="Self-incomp_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0713">Self-incompatibility</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0564285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="196" mass="23083" checksum="A05C86B8A3CDB464" modified="2022-10-12" version="1">MFDCHGFAKDMRDWSQRQGTCTSKSRLHTRSAIEEYTKLEIYSSAELKFIEFSHVVESFDMALRVIVFFLVMGSASMAFAKQSLADVTIVNSLPPESPPLHVHCKNRHKHDALSEHTVSYQQSVVFGFKPNQWGTTRYTCEFTWNRYHQEFPVWVDDYFFQTRPCTHCVWTVTVDGFFRNEAADGRFQQFVYYWKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1F3</accession>
    <name>A0A8T0H1F3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Beta-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G024400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 7"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1F3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22842">
        <property type="entry name" value="Gal_Rha_Lectin_BGal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000142">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.740:FF:000002">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000006">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048913">
        <property type="entry name" value="BetaGal_gal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041392">
        <property type="entry name" value="GHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019801">
        <property type="entry name" value="Glyco_hydro_35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000922">
        <property type="entry name" value="Lectin_gal-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043159">
        <property type="entry name" value="Lectin_gal-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21467">
        <property type="entry name" value="BetaGal_gal-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17834">
        <property type="entry name" value="GHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02140">
        <property type="entry name" value="SUEL_Lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01182">
        <property type="entry name" value="GLYCOSYL_HYDROL_F35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50228">
        <property type="entry name" value="SUEL_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274508" description="Beta-galactosidase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="SUEL-type lectin" evidence="10">
        <location>
            <begin position="760"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0565931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="841" mass="92744" checksum="24566C1A5990CEBB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H217</accession>
    <name>A0A8T0H217_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G185700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H217"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF4">
        <property type="entry name" value="OS02G0174300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="301" mass="34084" checksum="54D69C65AF6A5488" modified="2022-10-12" version="1">MDRAMPTIGVPRPAPGPSGTATSSQSKRARKDRGPNWLPSEIFALIGAKREMFLEELDTVDGRDLMTPDTSKWLRVSQCVMQAGFSPCLRDGPACKTKWNQMIPDNKKIADYLSRTGRNSLDYWEMNSAERKAEMLPRLFGQDVFDAIHEWFGNRPQIQPPHIRDLLSPTDSNYRQPQQQRQQDEEPDSMPSLARTASAGLPPGIHPHVISSSDTSQYAVHKRPGNTTVRRKSLSGHTMQEIADASRELERSKIEVQLKLFTEQMAYQREKDRRMYETATIANENARLAILKQGEMVSCLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2Q2</accession>
    <name>A0A8T0H2Q2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoenolpyruvate carboxylase</fullName>
            <ecNumber evidence="5">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G043300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + phosphate = phosphoenolpyruvate + hydrogencarbonate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2Q2"/>
    <dbReference type="OrthoDB" id="1365747at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.90:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000584">
        <property type="entry name" value="PRK00009.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF33">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="11">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0566166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="966" mass="109772" checksum="14F78B6DBB1AEAAA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H341</accession>
    <name>A0A8T0H341_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G168700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H341"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="157" mass="17089" checksum="DC0CBC135CEDF352" modified="2022-10-12" version="1">MPSQHSIKITPATLLPPKPQPNLTHHSYHISDTIQTSPLHPDLTHNTKDRLGRAIPTPDTEVPKGDIDTPRFKHGTSMRQHATSDSESDQDLGGVSRRGEKPKRGAREVKSVTSAYRKGDGAGAGLWRGAELARTEAELAANTPRWQFRGCQGSRGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6K5</accession>
    <name>A0A8T0H6K5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ALA-interacting subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G057000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6K5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="434" mass="49005" checksum="517E3539B81BEDCB" modified="2022-10-12" version="1">MTGILQAAEAEMEEEIALDDVGDLSTPNQIFMDDEGETSSTNQSFLDDGGETSTTNQSFLDDDGGSSVVKLLLLGNARGASLLTQLKQTIFHQLKYTKFTQQELPAWKPVITPKWAMIIFMVVGIFSIPIGIVTLAASHNVVQIVHRYDRECMRSKTLEDSVSYIQNPSVDHRCNVTLVVPKMMKNPVFVFYELDKFHQNHRRYMKSRSTKQHQGEDRRSVDSCHPIARVSKRDPIIPCGLIAWTLFNDTYEFGFVNSPNGPALHIPVVQTGIAWKSDVKVKFSNKVYPENFPNNINNSTGRSRFPVGGASLDPALPLSKHENLMVWMRTAPMPRFRKLYGRIEHNLHAGQVINVSIANVYNTYSYKGSKRLVLSTTSFLGGKNPFLGRAYLTMGVLCMLMALVSIFVQFRHPREFGDKTRLTWNREPSELYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6Q1</accession>
    <name>A0A8T0H6Q1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G150200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6Q1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1230">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34360">
        <property type="entry name" value="OS08G0519400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34360:SF1">
        <property type="entry name" value="OS08G0519400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58113">
        <property type="entry name" value="Apolipoprotein A-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770211" evidence="4">
        <location>
            <begin position="33"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="373"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="404"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="60"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0567636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="434" mass="48953" checksum="BC7250149123161D" modified="2022-10-12" version="1">MHIKNFKMATPRSLLLIVLFGLVCSIATVVRADEGIPPSYEYGNEIVALKSKLSLLEEGLKNKELSLSEKESKISKLEQELDALRTRKEETENTKLAQLKIDSAMSKVRELESQVKSLEEEADKLRVEADLHANRAKTVEDTATSHLTEKEKAIKALEDQKLRLQKAERGLQIAEAAMLKAKAEAEEKAKKLDDLHQSWLPPWAATHAETFTKTASDRWSTHADPVVKNFQRSASSKAADAHEYIKPHLDTFHTKVNPLIKEKWQKLAAAAAPHLETVKKAGVSSREYIAPHVETVQKTVNPYVEAVKVKSKPYVDQAKTFAAPHLERVNTLAGPHYRRVLTAANSYHEQVQSHLKEKLGQYKFLSSIATNEFIWFLAAALLALPFVTVFMFLRSLFVPKQVVHHKRHRSSHSGSSSTSKKPRRSRQADKQEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9K1</accession>
    <name>A0A8T0H9K1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G026200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9K1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="14003" checksum="B6C211B0AE0CDCFD" modified="2022-10-12" version="1">MLDISRYGSWSTMRFKLHDIADYAECPTNNKRITAQEFSLQSVCLAKNTSAGSQKAVTALQCRSWGGLQRVLIHIDDQVHVSVRSMVHKDQSQGKCRNASTWLRSASTHSHYNERYRRSNTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9T6</accession>
    <name>A0A8T0H9T6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G033100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9T6"/>
    <dbReference type="OrthoDB" id="1924566at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044174">
        <property type="entry name" value="BC10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003406">
        <property type="entry name" value="Glyco_trans_14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31042">
        <property type="entry name" value="CORE-2/I-BRANCHING BETA-1,6-N-ACETYLGLUCOSAMINYLTRANSFERASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31042:SF137">
        <property type="entry name" value="GLYCOSYL TRANSFERASE, FAMILY 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02485">
        <property type="entry name" value="Branch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="374" mass="42552" checksum="88679FE26C0C57D1" modified="2022-10-12" version="1">MAKSKISVSQWLGVFVVAVSLAGIISTSSSFADFLDIRNKSLGSSLTLINSSVIVIYEPQAREKNLSEYKPKRYLTDAQLLRDAAIARPRAGIPRIAFLFLVRGDIPHEPLWRRFFQTHEEKYSLYMHATPGYVYPKGSLFEGREIPSKLCPRFSRGIVDALRRLLAHALLDPRYNNAWFVNACESTVPIRGFPFAYQYLMRSKVSFVESFYPNSRYHSWQTSPEFNASDLRKGELWMALRRDHARVVVNDTEIYFKFQAGCTWWCTWDEQYVQTLLHLADAGGIAERTTMYVNWTEPHGGSPNGLSGTAGVIKELQSRVRDTDGERHDTAFDNTTYACVHNDVSPSPCFLFARKFASSQTKSLLSLNPQELGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9V5</accession>
    <name>A0A8T0H9V5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G020600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9V5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12684" checksum="525EF445242A8314" modified="2022-10-12" version="1">MWCGFISSLLPFPYLEPPSVTYNSFSSSENARPLGRVKPSATASTMPDPGAIRYIWFCTRGFDLCPFSLPYVVSVNQTEPSRLTTTSLGLLKGTPNQLSATIVVFSLLRSRRWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDC2</accession>
    <name>A0A8T0HDC2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G036100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11367" checksum="886B0BA3C1F8EBD4" modified="2022-10-12" version="1">MMYQSNYCHSNFHSAMKYRPNPTIEVCKSYLKAYHCYPLPTGKAEVVLVLTNCNHLDLITRVTLEHVPKIQVPPLGCNLRGIVCNCFTYVYWSRAILGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDN8</accession>
    <name>A0A8T0HDN8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cadherin-like beta-sandwich-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G088400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025883">
        <property type="entry name" value="Cadherin-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12733">
        <property type="entry name" value="Cadherin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035927135" description="Cadherin-like beta-sandwich-like domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin-like beta-sandwich-like" evidence="4">
        <location>
            <begin position="131"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="285" mass="30677" checksum="8B599BD80FC5A2DA" modified="2022-10-12" version="1">MRGGMVLWLGFVCVFLVLPSSSQEGVLHRVGDGGEGLKVGDNGGMGVSDMLEWTGLGEHASQGLLPLDVDLQKHHKHKHPPPPPSPPPPSPPPPSPPPPSPPPSPPPPSPPPPPPSPPPPPPPPPATVDSLEISNGALLIPPFDPDVHRYNTTVGEGVTQVHVTVSVPESFELYKVKLNSSKLVSGKQSPPIPIGENGETVNLVITISAPNHSSNKYYLSVHRVEKPSIWRRILKQSLVVVLVMLMIACILYISFSILRASPYSLRWLPLSRQRQYQPVNSDPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF98</accession>
    <name>A0A8T0HF98_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G163000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF98"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005882">
        <property type="term" value="C:intermediate filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045109">
        <property type="term" value="P:intermediate filament organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050405">
        <property type="entry name" value="Intermediate_filament"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45652">
        <property type="entry name" value="GLIAL FIBRILLARY ACIDIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45652:SF21">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 13-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="419"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="522"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="389"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="549"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="567" mass="64022" checksum="0232EE7A9921996F" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHZ0</accession>
    <name>A0A8T0HHZ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G051400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHZ0"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16667">
        <property type="entry name" value="RING-H2_RNF126-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000127">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF181"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710:SF4">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE AIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15710">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE PRAJA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="270"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="314"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0568912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="350" mass="39122" checksum="7BDEB7176F999E04" modified="2022-10-12" version="1">MKNGDAEPLQAVVAEHLKQLQKKQTFEAAAKALTILVQERYAGASPAEQNAIYGAVCRSATLLTTRFTGTAFWMAGLLLFESTAAVVSRPEEKKKINGFIKQANEFLGEQSERDESVPPSMRAGPSTPYLFEGQFPVGGGAEPPRPQWLQSQNMLASLIREQVQHMHARDEAASTEDRNEEGGEGQERTVQQLTEELQNIMETVNSRLAGENMVLNDEFIGLEEAIQATLQEIGSVPRGPPPASKEEVAKLPIIEVTKEFLETVGDDTECAVCRENMEVGDKLQEMPCKHNFHPPCLKPWLDEHNSCPICRHEMPTDDHEYERQKERDREAEEERKGAENAVRGGEFMYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ34</accession>
    <name>A0A8T0HJ34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beclin-1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G188400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beclin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043548">
        <property type="term" value="F:phosphatidylinositol 3-kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045324">
        <property type="term" value="P:late endosome to vacuole transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22265">
        <property type="entry name" value="UDM1_RNF168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.40:FF:000002">
        <property type="entry name" value="Beclin 1 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.40">
        <property type="entry name" value="Autophagy protein 6/Beclin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007243">
        <property type="entry name" value="Atg6/Beclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038274">
        <property type="entry name" value="Atg6/Beclin_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041691">
        <property type="entry name" value="Atg6/beclin_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040455">
        <property type="entry name" value="Atg6_BARA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768">
        <property type="entry name" value="BECLIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12768:SF4">
        <property type="entry name" value="BECLIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04111">
        <property type="entry name" value="APG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17675">
        <property type="entry name" value="APG6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Atg6/beclin coiled-coil" evidence="6">
        <location>
            <begin position="198"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Atg6 BARA" evidence="5">
        <location>
            <begin position="329"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="511"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="201"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="512"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="58757" checksum="A7E17641DB80CD77" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJG0</accession>
    <name>A0A8T0HJG0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G197500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7266" checksum="85AEDDDBD93B1770" modified="2022-10-12" version="1">MNYCGERREGGRGRHSLLWCSGIWQAASGRVAERGSVVSHLDLRISWWIGDGMEGGRCIFVRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK77</accession>
    <name>A0A8T0HK77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G215300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747:SF2">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="474"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="874"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1207"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="103"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="181"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="562"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="664"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="771"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="886"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="949"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1222"/>
            <end position="1233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0571154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1239" mass="139296" checksum="94CDFE8E5A33A7D6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKF5</accession>
    <name>A0A8T0HKF5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G222500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7457" checksum="855B6C69C51CA450" modified="2022-10-12" version="1" fragment="single">ARIVETSSILCWSDIAVWRQLLSGYVRFLVLILSNRIYASLSLGDTSVLAEARQLVLPIHAQGHTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKU9</accession>
    <name>A0A8T0HKU9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG010700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23115">
        <property type="entry name" value="RING-H2_BB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000226">
        <property type="entry name" value="E3 ubiquitin ligase BIG BROTHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043312">
        <property type="entry name" value="AtBBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048217">
        <property type="entry name" value="BB-like_RING-H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47530">
        <property type="entry name" value="E3 UBIQUITIN LIGASE BIG BROTHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47530:SF4">
        <property type="entry name" value="E3 UBIQUITIN LIGASE BIG BROTHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="326" mass="36136" checksum="FC1C68111ECD6558" modified="2022-10-12" version="1">MNSNSESAKDFKLDRSKEGAASGTTSDKEVVQQVEGSGSDAENNVANVDSPAPAPDSSTAARVPFTSLSQVDSDMALARALQEQERAYFLLQTGHGGGGFNDTDRFYYEGDHFDIPGDEENQDEEGKEEEEDEEDEDEEEEEVEEREDDPEEAGVEERAANDDEVDGANFDCDEAFARALQDKEDRDTTARLMALAGIYDIDGEFENDSNDSQEGTWEDVDPDNMSYEELIALGEAVGTESKGLNSQSIAALQQFTYVSDSKDNTSDQEQCVVCRLEYEDGDKMLSLPCKHQYHFECIRQWLERNKVCPVCSAEVMSESSTSEIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMF7</accession>
    <name>A0A8T0HMF7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG061100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8254" checksum="F20932286B48D2FF" modified="2022-10-12" version="1">MNSLAPLPYKFQAAIPYTYIRKNSPDQRARNFDCTSIPTHDKPNSLAPKKHEKPTATGAQNLAQNNHELNPPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMG1</accession>
    <name>A0A8T0HMG1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG060000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16167" checksum="6ECF35BB96420943" modified="2022-10-12" version="1">MESEFLSVAPLVQSVDVQVLGGSSPPCEVEKSLAWGCDLLDDNGDPLALSADGTLTKVWNFSELEAALLDAEVRLLQMEPPTGVLPPPAEAKSNFDQVYITWLQILLLLYYENRRCVAIMMFSEGSHKARSWLWLFLSSTLCRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN70</accession>
    <name>A0A8T0HN70_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG081400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="237"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="253" mass="26711" checksum="6CE0BBA265E08AFD" modified="2022-10-12" version="1">MYLSGVGAKRPPQTIADNSAQVAQPPVSARQPEPIPVQPPRGDEVGLPMSWSPRRYGRNPGSKRGAGNTSLPHSPVRSNATSKRLVLSPPEPPIAHPLHTVEQLGELCIIRDEPPASTFRKIEAIQHRGTQVATSSDASSSLHLADFPTQHLTSSPTDLPVACAQQSPCSSSSLPTSSPYAGSIPLSEATSKDGRLNLPQPCDSSNDSGARASSVRLAATYKAKWSAMTKRLEDATSKPTQSASTSTPPTRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP51</accession>
    <name>A0A8T0HP51_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG119400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="15861" checksum="D9EA8CD90B0F28BE" modified="2022-10-12" version="1">MCFENLRKVPGRQGCYLHRKSHHRRRSVYPAEEVPKPNGMEFGRADQRMLVHWDESDSHIAAPLHYENHLHLEQRFYYATYLDSVKGLLARKNVLLQIPRSFSLLILLLQTTKTLPRLHRLADNCRRLRCFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPA1</accession>
    <name>A0A8T0HPA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG107700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10245" checksum="D8E3B9DAE3C519F1" modified="2022-10-12" version="1">MSKTHSVERHRMDVNVRTIHPPLKDFAEYFMPTNAYCVEVCENAASYLEILQLIFSSCALGTFTDVLSRDLCGCKLLTGDSLMWRGRQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQI0</accession>
    <name>A0A8T0HQI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG143500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8971" checksum="C96509E3E33FE6E0" modified="2022-10-12" version="1">MASWECVIREGVLLKMLRQMTESSSPWDYPNFDAPNPLPRQLCSIADIENARNVSPRWREVIDSTAEWACVRQARYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSQ4</accession>
    <name>A0A8T0HSQ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG190700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSQ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6265" checksum="05380B8ED91A4F47" modified="2022-10-12" version="1">MRLLAREVDRAENGNRHLHKCQCNIFVASPSSKHSMASCRSTFSNSEGIFISGVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUL0</accession>
    <name>A0A8T0HUL0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG261600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUL0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14073" checksum="D3A12830FC8CA821" modified="2022-10-12" version="1">MGLVVELRKFFSINFEIRGYGGFFVDNSVRMEVGNEVGVRERANVGVEVLVRIEIRGDDDGNCIGVLFGCYASPMDILLKIRSIVGVGVANAIPIMVECEPKATKDFISGIWGIKLGELCGACEWKGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVC5</accession>
    <name>A0A8T0HVC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG281000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="9713" checksum="6533940EF3035DB5" modified="2022-10-12" version="1">MDNQPEVDQSPAPLRPTAMPVDGSHFGQPYAFSRPAQRPGAMAGIARPPPAITSPGASQAKQGRKDRGPNWLPQKILVLIRAKREQYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1W2</accession>
    <name>A0A8T0I1W2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G096400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1W2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000014">
        <property type="entry name" value="Probable dual-specificity RNA methyltransferase RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048641">
        <property type="entry name" value="RlmN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF5">
        <property type="entry name" value="RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21016">
        <property type="entry name" value="RlmN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="245"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0576653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="502" mass="55234" checksum="0584922718F0B4BF" modified="2022-10-12" version="1">MAMTRGGPVRVVASVGAAVAAGRFTSSTVSSVSLGGVYTVGERPQIRSAPRCLGCKAHAVECRLCKGNSTSDWVPSYDPAVARLYALPQRHSSRAQQRLNYAAKRQPWLIRGMTTESAVEAVEAGEIPVLKGTGEGDLSQQVTRKYLIGKTQEELEGIALSFGEQKYRGKQMHQLIYKNKIRTVKELAQIPKQLRDAMESAGWNIGRSPIHHVATSKDGTVKILLRLDDSRLVEAVGIPVKDKEGNAKLTVCVSSQVGCALKCAFCATGKGGFARNLKSHEIVDQVLTIEDIFRQRVTNIVFMGMGEPLMNLEAVLNAHRTINKELLIGQRMMTISTVGVPNTIRRLAAHKLQSTLAISLHAPNQDLRSQIVPSAKGYPLDALLEDCKYYFETTGRRLSFEYTLLAGVNDQREHAEELATLLHQWDLGRHVNIIPYNPIADSEFERPTKARVLAFVETLSKRRVTTSVRVTRGLDANAACGQLRNEFQKTPLQAPMELSVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2E3</accession>
    <name>A0A8T0I2E3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Amine oxidase</fullName>
            <ecNumber evidence="5">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G167900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="5">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the indoleamine 2,3-dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2E3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000898">
        <property type="entry name" value="Indolamine_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF41">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01231">
        <property type="entry name" value="IDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0186">Copper</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0801">TPQ</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035760833" description="Amine oxidase" evidence="6">
        <location>
            <begin position="19"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="7">
        <location>
            <begin position="157"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" description="proximal binding residue" evidence="4">
        <location>
            <position position="728"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="776" mass="87262" checksum="5A1DAEAF5E393CFA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3P6</accession>
    <name>A0A8T0I3P6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trafficking protein particle complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_5G206700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May play a role in vesicular transport from endoplasmic reticulum to Golgi.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Golgi apparatus</location>
            <location evidence="1 8">cis-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TRAPP small subunits family. BET3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3P6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030008">
        <property type="term" value="C:TRAPP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048193">
        <property type="term" value="P:Golgi vesicle transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14942">
        <property type="entry name" value="TRAPPC3_bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1380.20:FF:000006">
        <property type="entry name" value="Trafficking protein particle complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.20">
        <property type="entry name" value="Trafficking protein particle complex subunit 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016721">
        <property type="entry name" value="Bet3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007194">
        <property type="entry name" value="TRAPP_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13048">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04051">
        <property type="entry name" value="TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018293">
        <property type="entry name" value="TRAPP_I_complex_Bet3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="Ligand-binding domain in the NO signalling and Golgi transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR018293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0578120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="21069" checksum="9AE8A6D217F646D2" modified="2022-10-12" version="1">MRASLRPSDPAVSPAIERVNAELFTLTYGAIVRQLLTDYEEIEEVNKQLDTMGYNIGARLIDDFLAKANITKCTDFRETADVIAKVGFKMFLNVTATVANWSADSMECSLILEDNPLVDFVELPETCQGLSYCNILCGVLRGALEMVSMRTEVKFVKDMLRGDDVFEIRMKLLEQMPEEYPYKNDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4Z6</accession>
    <name>A0A8T0I4Z6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase subunit 4L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G183100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4Z6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035868735" description="NADH dehydrogenase subunit 4L" evidence="1">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="7221" checksum="75A14F21FBF26401" modified="2022-10-12" version="1">MLSLFFMLSLNILMKLSCEFCICEHSLLHSLCSYVFIISKTIVGLESCLSFFRIIHSRFLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I592</accession>
    <name>A0A8T0I592_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G187600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I592"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="17518" checksum="6F2826136F64E26F" modified="2022-10-12" version="1">MDHLQLEYQGTTFNNPAGITFSQGPAGFAQLHESAQAVSTECAEKVEAMLSTAVLHLADLWNMLTLEFSEGVAFDPDTALLTPVAEIPPVMLDAMKSKLENSLEWCQLARSRLTDITRSSKPYVSPYPSTINLQEPKSLWPVQPSVSPELRTYSFTTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6G8</accession>
    <name>A0A8T0I6G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G043200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035931428" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="126" mass="14415" checksum="C9E01BB251A1CB8A" modified="2022-10-12" version="1">MRSIKLWKSIPFLRLLVSSYTPLGINHAVVPTEHLAIGREGHLPKCMNYQLNVRLYVWLNEPRLQLNYPRTNCCSKPVQNRPCPYIYELRKNVSTPEVARPAFLARNSAAKVELISTILNNAGKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8Z2</accession>
    <name>A0A8T0I8Z2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G100700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8Z2"/>
    <dbReference type="OrthoDB" id="1630758at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000660">
        <property type="entry name" value="RING/U-box superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315">
        <property type="entry name" value="RING FINGER PROTEIN 41, 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315:SF102">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="152"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="251" mass="29016" checksum="EAA2F1AED145FB87" modified="2022-10-12" version="1">MLLLDMAQCKSYKESLKVLEADIQHANTLASEVPRDYDGACLQMRLSYSPVAHLFLFLVQWTDCSLAGALGLLRILIYKVYLDGTTTMSTQERKASLGEFYGHIYPSLQQLQAGMTGVEDLKQKAKCQERYKKRDEECSHMSEFDLEREIECGICMERNPKIALPDCNHVMCLTCYRDWRGRSQSCPYCRDSLRRVNSGDLWIFTDSADIEDVDKITRDNLQRLFLYIDKLPLLISESVFALYESYETHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9H9</accession>
    <name>A0A8T0I9H9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Remorin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G074800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the remorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9H9"/>
    <dbReference type="OrthoDB" id="684343at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005516">
        <property type="entry name" value="Remorin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31775">
        <property type="entry name" value="OS02G0117200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31775:SF5">
        <property type="entry name" value="REMORIN 1.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03763">
        <property type="entry name" value="Remorin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Remorin C-terminal" evidence="4">
        <location>
            <begin position="308"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0579128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="419" mass="45510" checksum="128ACF22A3698371" modified="2022-10-12" version="1">MTTMVMTAPQTPLPTSNGHTVHGTEETVPGGIHIDIAGLEEECYEEPCNQSTPRKPRAAAELPNNIFSSFKNVMFGSNGPIAPETQNGNPFAPVVEQAKGKKDVHIQEDQNDSSYDTACNGHSEEDPQEKLDFLPVREPQELASAFPPTFGHSSSSHAAEDQNNNPPASHPTNTTTRSPSRPSSPYVQGQDVHINCAQRNSAPGSTQGDAVVSATTIRSASFQSAKGEYPQSQFLLTISAPSPSGHYESGEMGLSYQHLSSHISEAPQQMVSKDVCQLPDCVNSRASGIVAAGGAQLEHLLARVKHEKTVSRARAWEEGAKAKAHNRYTRDESKITAWENTMKAKAEARMRKAQENLDKQRAKHIEKMKNAVASAHCKAQEKRAAMEARRAEDIVKAEETASRIRATGKMPRKCLCLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC23</accession>
    <name>A0A8T0IC23_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_4G176300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC23"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000548">
        <property type="entry name" value="ADP-ribosylation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0580479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21541" checksum="B6A9C51A4A23D564" modified="2022-10-12" version="1">MGQTFRKLFDSIFGNKEMRVVMLGLDAAGKTTILYKLHIGEVLSTVPTIGFNVEKVQYKNVEFTVWDVGGQEKLRPLWRHYFNNTDGLIYVVDSCDRERIGKAATEFQQIINDPLMRNSAILVFANKQDMKGALGTAEVCEQLGLFNLRNRRWQIQGTCAPKGEGLYEGLDWLATTLKQMQAAGVSTSVKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC67</accession>
    <name>A0A8T0IC67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G179200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC67"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009975">
        <property type="term" value="F:cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051762">
        <property type="term" value="P:sesquiterpene biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045:SF30">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="424"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="452"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="65194" checksum="A34CD181CB8E0BE0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC85</accession>
    <name>A0A8T0IC85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_4G185300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008331">
        <property type="term" value="F:high voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="entry name" value="Voltage-gated potassium channels. Chain C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050599">
        <property type="entry name" value="VDCC_alpha-1_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45628:SF7">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0107">Calcium channel</keyword>
    <keyword evidence="3" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="462"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="540"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="960"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="997"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1084"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1196"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="7"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="339"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="961"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="15">
        <location>
            <begin position="1272"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="301"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="854"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="312"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="863"/>
            <end position="874"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0580595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1483" mass="170126" checksum="509FAB8FAC5BBA0E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC88</accession>
    <name>A0A8T0IC88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_4G143700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016004">
        <property type="term" value="F:phospholipase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003500">
        <property type="entry name" value="ADP-ribosylation factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0580048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="181" mass="20724" checksum="2797E325B07CEDF8" modified="2022-10-12" version="1">MGLTFTKLFQKLFSKREMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRDRVVEARDELHRMLNEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRQRHWYIQSTCATSGEGLYEGLDWLSSNIANKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICS4</accession>
    <name>A0A8T0ICS4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">40S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G241100</name>
        <name evidence="5" type="ORF">KC19_4G163300</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICS4"/>
    <dbReference type="OrthoDB" id="1072458at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.860.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="entry name" value="30s Ribosomal Protein S19, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_uS19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_uS19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_uS19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_uS19_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_uS19_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003121">
        <property type="entry name" value="PRK04038.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="RIBOSOMAL PROTEIN S19P FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880:SF2">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="Ribosomal protein S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0580293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0592308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="17080" checksum="2EFE20907FC0AF66" modified="2022-10-12" version="1">MADAAEVEIQAPKKRTFKKFTFRGVDLDALLDMSSDELVELFHARARRRFQRGLKRKPMALIKKLRKAKREAPAGEKPEPVRTHLRNMIIVPEMIGSVIGVYNGKTFNQVEIKPEMIGHYLAEFSISYKPVKHGRPGIGATHSSRFIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICZ3</accession>
    <name>A0A8T0ICZ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G193400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCA family. CPR flippase (TC 3.A.1.211) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03263">
        <property type="entry name" value="ABC_subfamily_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000633">
        <property type="entry name" value="ABC transporter A family member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026082">
        <property type="entry name" value="ABCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229:SF154">
        <property type="entry name" value="ABC TRANSPORTER A FAMILY MEMBER 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19229">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12698">
        <property type="entry name" value="ABC2_membrane_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24526">
        <property type="entry name" value="ABCA12_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="475"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="656"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0580711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="978" mass="109001" checksum="1579B6E239A6B11B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID72</accession>
    <name>A0A8T0ID72_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein bL17c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L17, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">CL17</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G171100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID72"/>
    <dbReference type="OrthoDB" id="275000at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="entry name" value="Ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_bL17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_bL17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_bL17_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413:SF16">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="RIBOSOMAL PROTEIN L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="Prokaryotic ribosomal protein L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035747947" description="Large ribosomal subunit protein bL17c" evidence="8">
        <location>
            <begin position="24"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00072708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="22892" checksum="809ABB86625EE766" modified="2022-10-12" version="1">MAMAATSAFSMAALHAALPSSNATSSRATVTVSGLTVRRTAAVVVRSQAVTRATLAFQSFDGLRNENALQLRTGSTFGLMGLGISNGAKWFAMRHGRKIHRLGRPADQRRALLRGLTTEILRHGRIKTTRARATAMRKYVDHMITLAKGGSLHQRRQALGFLYDKQLVHSLFAEVPERYGERNGGYTRIIRTMPRKGDNAPMAFIELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEP3</accession>
    <name>A0A8T0IEP3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G013400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006502">
        <property type="entry name" value="PDDEXK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01615">
        <property type="entry name" value="A_thal_3542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579:SF39">
        <property type="entry name" value="OS01G0973600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04720">
        <property type="entry name" value="PDDEXK_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="43075" checksum="9EF9AEF1D529BC30" modified="2022-10-12" version="1">MPGFRCPGPTITAPSGNYSFLHDSQTPAGKESTWDRPVDLNYEHLPPVEAMPFDPNLHKACRPPHFHSEWMKGKGGSASNAFFGSGIPPPGLCPSPHGKDCNDYDEELAVMVDDFIESGSSSLLDGNDSDGGPPSIVKICNTLQTLTSSYGGIEGELLNAVWKLVLAIDFDTDLICNLEGADCRGGCIKRLVACRLRDAGYDAAVCKSKWEGSGHVLQGTVQMGEYEYIDVKVCCNQSVERLIVDVDFQDQFVLARATPNHLSALKLLPIVFVGTTKRLEQILQIMSESVKLSLKQNSMPLPPWRTLNFYHSKWLSSDHERIVDNSSRGRTSLTLKGRLPSMPEIRQCDVQLRRVKDSLLSEANGSSLNILARGRSSRPHSKSRGKRSIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJM8</accession>
    <name>A0A8T0IJM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G110200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0583111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="200" mass="21629" checksum="24D50D9537C4F36A" modified="2022-10-12" version="1">MTVRIANPAPLGLCGFALTTFVLSCYNAGIFGISLSTPPNVVVGLALFYGGLAQLLAGMWEFKTGNTFGATAFSSYGAFWLAYAAIHIPGFGIKQAYANGYEKDVLDAIGIFLLAWTIFTFIMWLGTLRANIALSMLFAFLTITFMLLTIADFRRSDTFKRAGGSFGIMTAIIAWYIALAGILTHENSYFTLPVGSLAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKH3</accession>
    <name>A0A8T0IKH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G130900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="631" mass="69527" checksum="A9F5FAE5EAA81EC2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRV3</accession>
    <name>A0A8T0IRV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Chitinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G091900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRV3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057016">
        <property type="entry name" value="EndoS_F2-like_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001223">
        <property type="entry name" value="Glyco_hydro18_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46476:SF20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46476">
        <property type="entry name" value="CHITINASE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23916">
        <property type="entry name" value="TIM-barrel_EndoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00451">
        <property type="entry name" value="CHITINBINDNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51910">
        <property type="entry name" value="GH18_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035916944" description="Chitinase" evidence="6">
        <location>
            <begin position="36"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="7">
        <location>
            <begin position="35"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="GH18" evidence="8">
        <location>
            <begin position="86"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="52"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0586460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="360" mass="38575" checksum="8AA979C1969AA798" modified="2022-10-12" version="1">MATLASSRGDRRLQQMTVALMLLAYSLSILQLVSAADCGSAAGGVQCANNLCCSQYGYCGQTSAYCGTGCQSQCSYAAPKGVLPGRILFDYLGSNGVAITFNDIPVTQSDITWVLGLSFAIDMSPTGVTQNGIFSVYWNPTLTKAAAKSWRAAHSNGRIVIAIGGSQLYSNNAVYDVNWYDPPNPTQWLANAVSSITTIVQDYGADGIDIDIERFPNGVGSTFQSLIGQLITTLKNRGVIRFVSIAPGYDQLARYTALYNSYSTYIDAANYQFYGEGLNTCAKYKTRYSQVIQSLPVGIVGLSTQVSGDPNTITGTTFYNCVTDIKNAGNNIAGVYLWNADLSKQLNNNFATEKAVAAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISN4</accession>
    <name>A0A8T0ISN4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G009900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10698" checksum="C7242C9208E0DCF7" modified="2022-10-12" version="1">MPSALRIAQCALPIAHAYALFPRSAVVFSAPEAFVCHCSHAIVPVPVPVLVLPQVPNCWLCLEVEELGTCHASPDASPQVLLCCHARRCASPLRCRGIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU02</accession>
    <name>A0A8T0IU02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G105100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="37130" checksum="F48C70828C892CF1" modified="2022-10-12" version="1">MEYRGKHILAPMVRVGGLPFRMLAAEYGADITYGEEIVDHKMLRCERVVNEFLGTVDFVERTTKEVVFRTCDAEKERVVFQVGTADAVRCLKVASSVAGDVAAFDVNMGCPKSFSTSGGMGAALLGKPELIHDILTTLRRNLSIPVTCKIRLLETYAETVELARRIETTGVAALAVHGRRVKDRTHRDPAQWDGIQEVVSALSIPVIANGDVLEYGDFQRIEDATGASSAMVARAAVWNVSVFRPEGLLFWEDVKSEYVRKCVEWENDVHWTKHTLREMIMRHSNLESAEGKALARCKTLGDVGDLYGFQSYRRELEVSRGGSEIVSYTEDCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX85</accession>
    <name>A0A8T0IX85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G236100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="6">
        <location>
            <begin position="101"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="17889" checksum="1A09A3561DB9149D" modified="2022-10-12" version="1">MALAVNARSAVSTAVPAQAVSGISSLKQATSVRFTNGAVAFKRASLVVRAEGKTEPGPGGRGNAPTTPTSPPGLSGTEIPLSVITSSAPLAQGSDKPVGERIAYVCQDCGYVYDQETPFEDVSDEYNCPQCSAPKMRFTMANASVEEMLDTTKEDDAVSRGSGEKSGSPPTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYZ6</accession>
    <name>A0A8T0IYZ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase</fullName>
            <ecNumber evidence="3 12">2.4.1.131</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G176800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes, on the cytoplasmic face of the endoplasmic reticulum, the addition of the fourth and fifth mannose residues to the dolichol-linked oligosaccharide chain, to produce Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>an alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + 2 GDP + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:29523"/>
            <dbReference type="Rhea" id="RHEA-COMP:19515"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:132511"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="EC" id="2.4.1.131"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11 12">
            <dbReference type="Rhea" id="RHEA:29524"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.131" evidence="3 12"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004377">
        <property type="term" value="F:GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03806">
        <property type="entry name" value="GT4_ALG11-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038013">
        <property type="entry name" value="ALG11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031814">
        <property type="entry name" value="ALG11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45919:SF1">
        <property type="entry name" value="GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15924">
        <property type="entry name" value="ALG11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ALG11 mannosyltransferase N-terminal" evidence="14">
        <location>
            <begin position="39"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="13">
        <location>
            <begin position="267"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF15924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0587603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="474" mass="52584" checksum="5CCCAFEC536F3E96" modified="2022-10-12" version="1">MEMQQLGRWLLSAGLATALLCVGILWTALVRARRGIKPVVAFFHPYTNDGGGGERVLWCAVRAIQEMAPGLDVVVYTGDLATPDSLAARALDRFGVKLVKAPQVVKLERRKWVEAKTYPRFTIIGQSLGSIILAWEALSKLTPLIFLDTSGYAFTYMIARAAGSFVVCYTHYPTISTDMLERVRSRASLYNNDVRISRSFWLSSIKVWYYRIVAQLYGLAGRCAHLVMVNSSWTRAHINAIWKMPDRTFLVYPPCNTLTLQALPLERPQQNQYIVSVAQFRPEKAHELQLEAFALALEQLSLQNTEARLKLVGSCRNQEDNDRVESLRLKCRERGLEQNVDFCLGVSNTEMVELLGGAIAGLHTMTDEHFGIVVVEYMASGAVPIAHNSAGPKLDIVVNEGGNRTGFLASSVSEFADAMCHVVTMPADERMKIAQAGRVRAARFSESKFDSAFKEAISPILEEAMKCAGIIRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2C5</accession>
    <name>A0A8T0J2C5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxypeptidase</fullName>
            <ecNumber evidence="5">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G040600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2C5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11320:FF:000002">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000211">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF470">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035966882" description="Carboxypeptidase" evidence="5">
        <location>
            <begin position="34"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0589697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="497" mass="55867" checksum="427D2859B7EA4454" modified="2022-10-12" version="1">MAGEFFSRGPSVVAVLVLLVVTFLHLTVSSVNGTLVVEQSRNGGRRSLLENGNWKEQQEADRVWLPEQPAVNFSQYAGMVTVNATAGRAYFYFFVESPDHPSSKPLTLWLNGGPGCSSLAYGFAEEFGPYRILPDASGVYLHEYAWNRASNMLFLESPSGVGFSFSNVSSENQIGGDKRTAEDNYMFLLNWFERFPQYKDREFYIAGESYAGHYVPQLAKLIVDRNPEAELKINLKGMMAGNPVTDAYWDNVGNIDYWHSHALISDQTWENMKKECNFSDPDCCSKACDNLYTFAQTYELGQIDPYSIYTANCLITIGANSMRTQKSYLNVRPDNPFTRARRGYDPCTGNYAEAYFNRPEVQRALHANVSGIIPYNWTGCSGELQNWTDSAFSVIPEYKALIKAGLKIWVFSGDADSVVPVTSTRYALAAMKLSIKTPWHAWYHHQQVGGRVIEYEGLTYVTIRGAGHEVPLLQPGRAFHMFKSFLAAKQLPKSSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2S9</accession>
    <name>A0A8T0J2S9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Peroxidase</fullName>
            <ecNumber evidence="3 17">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_1G051500</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="14 17">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="14 17">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="3 17"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2S9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 17" id="KW-0349">Heme</keyword>
    <keyword evidence="17" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 14 17" id="KW-0408">Iron</keyword>
    <keyword evidence="6 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 17" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0964">Secreted</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035968057" description="Peroxidase" evidence="17">
        <location>
            <begin position="34"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="18">
        <location>
            <begin position="36"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="15">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="46"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="79"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="128"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="207"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0589827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="36596" checksum="D2D6AB60362C85F6" modified="2022-10-12" version="1">MAGARGGGHGFVIMMQYWALGFVIAQLLQMAESQGGLQVGFYDQSCPLAEQIVRTVVERGVLQDHGNAPGLIRLHFHDCFVQGCDGSVLLDGAKSEKTASPNFSLRGFEVVDSAKAELEKQCPGVVSCADLLAFAARDSIELTGGKRWEVPAGRRDGNVSDNAEAEAMLPSPSLDVHQLTDSFTRKGLSQNDMITLSGAHTIGRIHCSTVVARLYPTTDPNLDADLAVQLKTLCPEVGGNSSSTFNLDPTTPELFDNMYYSNLFGGKGVLQSDQILFESWSTKLPTMFNVLSTTSFTSSFADSMLTMSQIEVKTGADGEIRRHCRVVNPVIAASSPASPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J302</accession>
    <name>A0A8T0J302_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G014200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J302"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025322">
        <property type="entry name" value="PADRE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33052">
        <property type="entry name" value="DUF4228 DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14009">
        <property type="entry name" value="PADRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="241" mass="27587" checksum="FF2F93F1C9DBB48E" modified="2022-10-12" version="1">MKTPQSMATKGQGMLFCNCICSWQPVRVVHGDGHIRSLTRPVTVGELLKHHPHHFVCEPTSNGPLYHSGMLPLDMELEEGRIYLLLPLPRLLPHLASTFPNPPCCPCFSHRETMHSNSAQKYDSKSFSEEHSRLKSWLARNQDQFLVAASTMRKFRHRVVKSKLVRSLVRMSKRMLPDRLRLRLSFQKLEDFSKGSTSSSVVGKSVQYCSRNRWRPGLECISEVDLLTGLLRDSVEVGEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3L0</accession>
    <name>A0A8T0J3L0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 18">Peroxidase</fullName>
            <ecNumber evidence="3 18">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_1G033200</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 18">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 18">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="15 18">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 18">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15 18">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="18">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="3 18"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000008">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF48">
        <property type="entry name" value="PEROXIDASE 16-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 18" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 18" id="KW-0349">Heme</keyword>
    <keyword evidence="12 18" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 15 18" id="KW-0408">Iron</keyword>
    <keyword evidence="6 15 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 18" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0964">Secreted</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035965941" description="Peroxidase" evidence="18">
        <location>
            <begin position="37"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="19">
        <location>
            <begin position="37"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="16">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="47"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="80"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="129"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="17">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0589606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="327" mass="34731" checksum="FE302C33FFF11489" modified="2022-10-12" version="1">MADAQVMLVISAARGMLAFVILMAALVLCSSTGVEATLRSDFYSSSCPNVENLVYQAISKAYWSDSTVAPGILRLSFHDCFVNGCDASVLIKGSTTERAAIQNAGIHGFEAINAAKWAVEQMCPGVVSCADILQYAARDTVKLTKGLGWSVPAGRRDGTVSLATDPPLNLPPATFTSSQLVANFAAKGLSAEQMVILSGSHTIGVTHCLQLRDRIFDVIDPTMPKDLLATLQAACPTNTTPTALTIDRSTVNTFDTKYFSNIASGYGLMTSDQTLFADPATRPYVEANLQQGAFDSNFAAAMVAMSSISPKVGSAGEIRRHCEYFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J434</accession>
    <name>A0A8T0J434_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G038200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J434"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="557" mass="62344" checksum="F203AA52E38AE9B5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J442</accession>
    <name>A0A8T0J442_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Mitochondrial uncoupling protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G121100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J442"/>
    <dbReference type="OrthoDB" id="6703404at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005310">
        <property type="term" value="F:dicarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000030">
        <property type="entry name" value="Mitochondrial uncoupling protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="10"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="125"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="225"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0590704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="318" mass="33918" checksum="A92B51BAC6DAC12B" modified="2022-10-12" version="1">MVFFGNLEWQGFAEGGMASMIAGFSTHPLDLIKVRMQLQGEGAAPALAYATLNGSASGNVDVVGRRAGPLRVGLDVARTEGVKALYSGVSATLLRQVLYSSTRMGLYEFLKHRWQDQGPHEGSGLPLYKKVTAALVSGGFGAVVGNPADLAMVRMQADGRLPVHERRNYTSVGNALSRMVRQDGVRSLWTGSAPTVTRAMLVTAAQLATYDQIKDTIVENHLVPEGFATQVLASCGAGVLASVASNPIDVVKTRVMNMKVVPGEAPPYRGALDCAVKTVRAEGPMALYKGFVPTVTRQGPFAIILFLSLEQIKKVIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4G2</accession>
    <name>A0A8T0J4G2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G072700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4G2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11867" checksum="1EDFE6AADD04DFC7" modified="2022-10-12" version="1">MEKCSQMLLRGKCSRVKRKQERPEHIIGGNDANRIVRGADHIPPSRQIRTTTGFTMVPHDVIHMSIEHMSIELNSIGCHVTNDSNRKSQVLSSLSVIRILSKTHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5D5</accession>
    <name>A0A8T0J5D5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G095400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5D5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF9">
        <property type="entry name" value="PROTEIN DETOXIFICATION 46, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="611"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="677"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0590386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="748" mass="80273" checksum="8A86A0EA6367A187" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J648</accession>
    <name>A0A8T0J648_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G120900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J648"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12504" checksum="1CF0DC95CC72D67B" modified="2022-10-12" version="1">MQKVHHALCAQMNPKLVSNSAKHNTHQTPGTLPNLLYQTLVTPHCLFVLKIQNQKRRLSIDTSSMRTNVTEMRRRQSTPILTTPSSNTITLQHNISHDIKSQTITQLNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6A5</accession>
    <name>A0A8T0J6A5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G090900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6A5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010190">
        <property type="term" value="P:cytochrome b6f complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044970">
        <property type="entry name" value="CCB2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021325">
        <property type="entry name" value="CCB2/CCB4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36403">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36403:SF1">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11152">
        <property type="entry name" value="CCB2_CCB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035812069" evidence="1">
        <location>
            <begin position="16"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="298" mass="31680" checksum="0F09080FF57F2BD6" modified="2022-10-12" version="1">MALMMMRMAVVGGRGVLCSLHCLSASPSRFVSALARPGQRIVGARPGLKGWQASQRVAVARAGNDEPGGAEVDVSVFRFTLGIPGFDDADLPRLVGVFFGSLLLINHAVSIESMTNAQLTSEVLGLFLAAVACSLPSVGRRLKGGEAGKEGNKGPGRRSVFELARRLSGKQKQELAWGTFALLQNTKTSAVIVWHRGEVVGARGSLGLEGGVQALPQLQKMLNDSPVISSSGPLYVSNGADTKGWPIVPKDAKSILVQPFEGEDGGLILLSYQPRSYSSKDRTWVTMLAEKFSQAFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6M4</accession>
    <name>A0A8T0J6M4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G131900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040262">
        <property type="entry name" value="At4g38062-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45287">
        <property type="entry name" value="OS03G0691500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45287:SF4">
        <property type="entry name" value="OS03G0691500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2664"/>
            <end position="2701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2723"/>
            <end position="2754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2814"/>
            <end position="2856"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="589"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="725"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="830"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="953"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1348"/>
            <end position="1375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1401"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1617"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1863"/>
            <end position="1908"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1933"/>
            <end position="2024"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2122"/>
            <end position="2209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2263"/>
            <end position="2364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2405"/>
            <end position="2474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2511"/>
            <end position="2587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2684"/>
            <end position="2695"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2856" mass="324844" checksum="9AAA0A581E1F9E38" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7C9</accession>
    <name>A0A8T0J7C9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxynucleoside kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G152400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7C9"/>
    <dbReference type="OrthoDB" id="567086at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050566">
        <property type="entry name" value="Deoxyribonucleoside_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513:SF35">
        <property type="entry name" value="DEOXYADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deoxynucleoside kinase" evidence="1">
        <location>
            <begin position="274"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="579" mass="64274" checksum="48BDC4A5F41732F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8T0</accession>
    <name>A0A8T0J8T0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G224700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8T0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035735520" evidence="1">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="6985" checksum="A1A94D7CFB94461E" modified="2022-10-12" version="1">MSGLLSQYHLVLFSLDTLVSVTLLEIESGKDISLQQYSRAMHGSLLANYSATYGTKNDMTKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9A0</accession>
    <name>A0A8T0J9A0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G255500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9A0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF12">
        <property type="entry name" value="GALACTAN BETA-1,4-GALACTOSYLTRANSFERASE GALS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0592480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="60519" checksum="CF20968029426C86" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB77</accession>
    <name>A0A8T0JB77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G214500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14760" checksum="AF368C7FD30E18F2" modified="2022-10-12" version="1">MLPLFAQAHRPARSPALSAHPSEWLNSLRISTPDNCDHNHGTAWAMRCKLVRAAAARDGKLGEAHALLMSIGFRRGPHHLPRGTMHQMLNKQLGCAKEGAGVRVSDMCMETNRRSLSSVALSLVRNLSDCIETLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC34</accession>
    <name>A0A8T0JC34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Peroxidase</fullName>
            <ecNumber evidence="20">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_1G299400</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="17 20">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="17 20">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 20">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="20"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17 20" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 20" id="KW-0349">Heme</keyword>
    <keyword evidence="20" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="12 17 20" id="KW-0408">Iron</keyword>
    <keyword evidence="8 17 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 20" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="21">
        <location>
            <begin position="44"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="18">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="54"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="87"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="136"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="215"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0593025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="316" mass="33617" checksum="DDDD302D9EBDA674" modified="2022-10-12" version="1">MGRRVANSAVQGPLYGVRGWLQPCCWAMVVVMLTMQSQMGMVVALRVGYYAQSCPNAEGIVRNAMARAMQRDTGTAPGVLRLHFHDCFVDGCDGSVLLEGPNSEKAASPNLSLRGFEVVDEVKADLEAVCPGVVSCADILAFGARDAVEMTGGVGWAVPAGRLDGRFSSAASASANIPDPAFDVGQLNNMFARKGLSQSDMIVLSGAHSIGRAHCVSVKNGSPLKAACQGGATFNLDPTPNRWDNAYYANVINQQGVMNSDQILFDDVGTRAETTLNAVLDAAWQVRFSQVIVRMGNIGVKTGPDGEVRRNCRFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCI2</accession>
    <name>A0A8T0JCI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G261000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCI2"/>
    <dbReference type="OrthoDB" id="2942533at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47541">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47541:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="23486" checksum="27C7612AE176C446" modified="2022-10-12" version="1">MSSVTKTERAHQKYRAGQYAEALVLYTEALNAATQLNHQIALHSNRAACHLKLQEYKLAAEECSAVLELDAKHAGALMLRAQTLVAMKDYHSALFDVNRLLEANPNSEVYKNLQARLKTQMALAPIPEAENETPPDSPTHQQLQRKLPALAEPPKPAGWAAIPKPKGHTGVDYSRWSGLGDDISSDDEEEEEEPQYQYRLTNVGLSNFRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD40</accession>
    <name>A0A8T0JD40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G317700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="460"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0593276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="497" mass="58431" checksum="5D2555D7618F5D1E" modified="2022-10-12" version="1">MRAYIPFDRVGDFLRGQTCEGGIEVGWNVAERIQGIHVLRPQVDSYIEHVYYECPFGPKDLRGDPTHPHSKKRGCLARFSIKQLLLRPDVAEVAYYQVDHNREDGTPAHGLEDKDFIGRKSAYQPRMSLELKKWIKTRLSEGFTAKQVYEEHRRNLIERRKEHPENVFMWHEKDDVTDLPFILGIQTPWQKEMLKYGHNGAIAMDATFGTNVPKYPLYSLLVFDHWRNGIPVAWVLSSRSSEEDLVMWLEPLRRNLEGTRLDFLPSCFIVDDAVEQRNALKRAWPESEVLIYLCAFHVLKNWKNHIWTKVPNLGSLREFVYRQLHSLLYMPIEYQETEEDFLKQMYLIGHRRNPHSNQDTQASIESYHAALKRWMKIDNHQLRGRRMDSLVWRLTNPIETHYMYNDGRKSNGFVLNKHVEKIVASGIAKAKAIPIEHVRRHHAIEGLWQVHSQSALGRWYDIMDPYIKYASCSCEWAIRRNMCKHQLVIIKCSTDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDA3</accession>
    <name>A0A8T0JDA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G330200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDA3"/>
    <dbReference type="OrthoDB" id="418274at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bulb-type lectin" evidence="1">
        <location>
            <begin position="44"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="18797" checksum="A03FCDD56FE1A925" modified="2022-10-12" version="1">MHCRIGEAVRSPAFQGAAMCIFRSRLCLLLNVLACIVRVIHGQSAIIVAPKEIPTGGALQSKNGRFLLAMQYDCNLVLYDLEKNRLPLWATNTSGHGANCYAAMEINGNFVLYNGAHMIKFQTYTYIYSCTGNYLAWMQDDGNFVVYCEPTVNNLQQLTALWATGTDGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDY4</accession>
    <name>A0A8T0JDY4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G287600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDY4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="201" mass="22056" checksum="A0C1AEA07726EB38" modified="2022-10-12" version="1">MKTRQREEAQAQAGRQAVGTPGPQLVAPTQGRAGQGRLLNEGSETRTRTPGAPEFVDQIAIANRATNHAAYSHPSLARPGETERERERSEQWSHALKCHSRALSWTRRLPIAVTRTGGEGGREGELCRWCCEDWICGRRGVAERGRAGWKTLRAGMEFRPFEGVARFGEDSGRIGFKGAAAGAASVTCWRDTIAFGLLWLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G2C7</accession>
    <name>A0A8T0G2C7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G000300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G2C7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="357"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="428"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0553300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="482" mass="52775" checksum="E241B75F3975019A" modified="2022-10-12" version="1">MGTRERANALGRYRCDRHDLRGAKRTAEMKRGGKTLTRGGGRSARARGEAHGERRSFSSAPVVLAGLFGELGAQTIHVAMAAAAARPLVTVQNVDGSDQGVQATLPAVFLAPIRPDVVATVHTALAKNKRQPYAVSVKAGHQTSAESWGTGRAVSRIPRVPGGGTHRAGQGAFGNMCRGGRMFAPTKIWRRWHRKVNLNQKRYAIASALAASAVPSLVLARGHKIEEVPEVPLVLGDAAEGIEKTSAAVKLLKSLGAYADIEKVKASHAIRAGKGKMRNRRYVSRRGPLVVYGTEGAKLVKAFRNIPGVEIVSVDRLNLLQLAPGGHLGRFIVWTKSAFEKLDAIFGTQEKKSLVKKNYTLPRNIMGNPDLARIINSDEIQSVVRPTKTVIKRRVLKKNPLKNLGALLKLNPYAKTARRMELLAQERQSKAKAEKLQSKRSQLKPEEKELIKKQGASWYKTMVSDSEYTEFENFTKWLGVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5T2</accession>
    <name>A0A8T0G5T2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine synthetase</fullName>
            <ecNumber evidence="2">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G039000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5T2"/>
    <dbReference type="OrthoDB" id="1936100at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000004">
        <property type="entry name" value="Glutamine synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050292">
        <property type="entry name" value="Glutamine_Synthetase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852">
        <property type="entry name" value="GLUTAMINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20852:SF57">
        <property type="entry name" value="GLUTAMINE SYNTHETASE 2 CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS beta-grasp" evidence="9">
        <location>
            <begin position="143"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="10">
        <location>
            <begin position="234"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0553787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="484" mass="52601" checksum="9BD7FE4AEEA7C6FB" modified="2022-10-12" version="1">MGAGYPAEQRRVSSSCLESRQYLKAEPVVAVARPADELYLKTRPALLSTHSRIDAASVSSSSTKMAAASISVSKAAVTAQLAPSSHVSKASSLKTLPLSAGQASGFGVSGFFSNKNELRSTVSAVKSFTPRQGGVFKIVALAQKAEYIWMDGQEGQKGIRFNEMRSKTKVLQRPIRAGSLDFPQWSFDGSSTGQAEGKFSDCILNPVFTCPDPIRGENHVLVLCEVLNPDSTPHETNTRRKIQDILSPDVLAEETLFGFEQEYTMFNKACKVYGWPEGGFPHPQGPFYCGVGLEAVYGRPLVEAHMDACIKAGLKISGINAEVMPGQWEFQIGPAGPLEVGDHVMLARWLLHRLGEDFGITCTFEPKPMEGDWNGAGAHTNYSTKTMREEGGIKAIHAAIEKLSKKHAEHISQYGLGNERRLTGKHETANINTFKSGVADRGASIRIPLGVSLEGKGYLEDRRPAANVDPYVVSRMLIQTTLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7M9</accession>
    <name>A0A8T0G7M9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G162100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33625">
        <property type="entry name" value="OS08G0179900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33625:SF4">
        <property type="entry name" value="OS08G0179900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="326" mass="35664" checksum="DE3198D5C3328EF2" modified="2022-10-12" version="1">MIQSLQVGKQLPSVPASPPPAASKAGECRVCDSAGFLSTQKLSSAGSLSCTCKALDGYYIPESHSVFKVYEDEVNPLDDWEFAGDEEKEAAEDVEASAESSRYLAGAITVPDLLQLSLALPREAFPSIAGGSDLSNSSIEVRTEHDGHVDEELGQSRACDWLEPPSPCGAVPMQETHHQMGGEVVMLEAFQQFQHNPQIQEMVLALATDARVWQAVLANKKLQEYTTGSAEGNVEVRITQDLDSAALQGRRFSNFVVISHNSLRELKAGLREQMRVVMDVVEKRLQAETRQLMLDLMVRALTMMSIFMLTLIGFLILLPLQVSRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8P7</accession>
    <name>A0A8T0G8P7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G028100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8P7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.700">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="410"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="533" mass="54781" checksum="D849AB0C6F0E07A4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBU4</accession>
    <name>A0A8T0GBU4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G113800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032870">
        <property type="entry name" value="ALKBH7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052:SF0">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21052">
        <property type="entry name" value="SPERMATOGENESIS ASSOCIATED 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="147"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0554722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="261" mass="29084" checksum="544A1C1CA73F4F1B" modified="2022-10-12" version="1">MAEETRELYAAVFGTDSDSDSGSEEEAQGGLIVDSDVEWEQEEDQKRGLVDTKHVGHVWEPVEGVEGLWRCGEFLDPVEQESLVKAIEGEGWFEEPAHNQAMRFGLLPGWAVTLSSMIFASISRFQGLGLGFGDGVLREEILARKPLFDQMIVNSYQPGEGIGAHVDLARFEDGIVVLSLLSSCVMRFGRCGRVDEKVDVLLSPGDLIVLSGDARYGWTHEINRERAEEQMWAGEVLEQARRISVTLRRLCPEENVHSMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBX0</accession>
    <name>A0A8T0GBX0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G036400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="595"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="508"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="649"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="699"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="807"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="219"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="330"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="547"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="568"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="701"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="808"/>
            <end position="818"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0556225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="848" mass="93131" checksum="2744AE17EE4A6348" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFD6</accession>
    <name>A0A8T0GFD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">cyclin-dependent kinase</fullName>
            <ecNumber evidence="2">2.7.11.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G061000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="2"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010556">
        <property type="term" value="P:regulation of macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080090">
        <property type="term" value="P:regulation of primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07843">
        <property type="entry name" value="STKc_CDC2L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000172">
        <property type="entry name" value="cyclin-dependent kinase G-2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045267">
        <property type="entry name" value="CDK11/PITSLRE_STKc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="494"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="801"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="128"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="277"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="375"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="815"/>
            <end position="835"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0556538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="835" mass="94213" checksum="D1BF6CEBEA12B66E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFW6</accession>
    <name>A0A8T0GFW6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G019400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFW6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="198" mass="22584" checksum="E71A427269FDD4CD" modified="2022-10-12" version="1">MAYVADKGVVSTETDRNSESVRAQILVSISDDRRLSAALGELESTSALLERSVHRNKKQIRATHDEIWRLVGHYCVFQVVLLLAVGQVNVPECRNLWAPFLLSALSSIITFRGICVKYWRIRSLENIVSSEDRTLKVAVKRIYELKQEGSNYFNLSSHRDDYVKPKSRPAVIDYFVVLPLVSFSVIVLASIWQTLCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG95</accession>
    <name>A0A8T0GG95_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G141000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05476">
        <property type="entry name" value="pepsin_A_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034161">
        <property type="entry name" value="Pepsin-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051708">
        <property type="entry name" value="Plant_Aspart_Prot_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47967:SF128">
        <property type="entry name" value="ASPARTIC PROTEINASE CDR1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47967">
        <property type="entry name" value="OS07G0603500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751756" description="Peptidase A1 domain-containing protein" evidence="6">
        <location>
            <begin position="30"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="107"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="49766" checksum="19AA1FA8FBB68D72" modified="2022-10-12" version="1">MAAVRDLSLTARWMLFLAVFMSWQYSTQASRFLQSIDTSKDGGSKIIRSELIHRDHPLSPIAPAEGTTFSDRLQAAAKRSRDRSLLMSRGRRLSAFTTPFTSESFEYVISISFGTPPQLFTGMVDTGSDLVWIQCSPCINCFKKHPHPVFDPTTSSTEAYVSCNDTNLCNQSNFGCEPNSPYCQIKYSYLDGSQTEGVLTNETMTLPNTAGAAPVASNFVIGCMNNNTGIFDNYDGIVGFARGPLSLPSQLSKRGDLNVFAFCLVPYTATTTLTSSLIFGSRNETNPLGLEYTPLLDGRFYWVDMVGVSVAGVDTGIPSALFNTSGGVIFDSGTTYTQFAPAIYDSIKQSVANVIPYPIVPDSSNSSLCYDVAGVQNPTWPTMTYHFTGVSGAIVDFELDLENLFPQEPNTTVFCMPIISGGDNIIGNIQQANHYIEHDVDLKRIGWISKDCTVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGA9</accession>
    <name>A0A8T0GGA9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G147800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGA9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="6325" checksum="3B1A2B68286957BC" modified="2022-10-12" version="1">MYRCMFYPRVPFWKAPYVLLLNLWGVKGEKRRFAYDWVPSQGSFNYNLRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHM9</accession>
    <name>A0A8T0GHM9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G068300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035880789" evidence="1">
        <location>
            <begin position="26"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7031" checksum="84E1B127C31ADC98" modified="2022-10-12" version="1">MICVRLLPLSISFDVIFLMLSKLDSGCLRTPEGSQLLVALKQVLVPVMHIFCRDDLIPSLEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI05</accession>
    <name>A0A8T0GI05_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mannan polymerase II complex ANP1 subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G126500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ANP1/MMN9/VAN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052086">
        <property type="entry name" value="Mannan_Polymerase_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083:SF6">
        <property type="entry name" value="MANNAN POLYMERASE COMPLEXES SUBUNIT MNN9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43083">
        <property type="entry name" value="MANNAN POLYMERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03452">
        <property type="entry name" value="Anp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00037964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="359" mass="41089" checksum="8909AEDBFDFCC155" modified="2022-10-12" version="1">MVIRKRIFVAAISVLSVLWLLFLVSNFSSTSWNEIFSSFGGQRSYENSEELTGITNIWTPKQPLEVFTEIAQSSPEIPGPEMLSNGYPDVLILSPLKQVSGHIKSYFTLLHSLSYPKNSISLGFLVSDSDDRSYDLVRDHFLQRKKVVTNQTEKYRDVTLVHQSFSYNPGSNWVDIHGMRNQIPRRKVLAKSRNYLLFSSLRPHHEWVLWIDSDVSHYPPTMVQDLLNFTGPDKHILVPNSYWRDDKGEEHPYDRNSWRETPESRKFLKQTQEIVVFEGYSAYTTGRISLGDLRGSNESVVKLDAVGGTVLLVRGRLHREGLVFLPVPYEKAIETEALGKLALGMGYQPWGLPNYITIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI18</accession>
    <name>A0A8T0GI18_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G043600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6545" checksum="B4F572DAEA626FC2" modified="2022-10-12" version="1">MMLDRFRILKLGFRCVCCMYGRSQKGTSSVSSSTRTNRMWNLDVSVAIALDGLPSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLF5</accession>
    <name>A0A8T0GLF5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G176000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11183" checksum="3746B0CAFA23DE80" modified="2022-10-12" version="1" fragment="single">IYNALSCVFHLRKQNKENLGAIRSDASLRGDPTTKRYARVKFLSSKSFEPPFLINFSLTLKTCTSHCLKTPSLRIKIVRHKNGSLPTESRSMNSNLTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR58</accession>
    <name>A0A8T0GR58_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G120000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000056">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 72B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045:SF20">
        <property type="entry name" value="UDP-RHAMNOSE:RHAMNOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="57777" checksum="1A309E637CD5D714" modified="2022-10-12" version="1">MVSFVMERDAPHVVMVPSSSSGHAIPFLQFARRLAAEGVVTTVVTTDRHVRELEKTVRSTDLTPQGEPLRILGLRDKKVEISHDEWRRQVREVPEEKLEVMRLLREAVTDVGSPQSWKLRGVAPASPPVCILHDMFVPWAQEAAEKLQIESHLLYVSAAAALSVDLESNRLFDEGRLPITRERRDMVFPDIPGLSPIQALDFAVPYLMPAMYEWMRKYYSRFRRTDVILVNTFYDMEKPVLDALRNQVIGSPDMQAKCILEIGPLLPESHVNEDTVEVEVEERDPCILWLDRQAPNSVLYISFGSFATLEAPQLLELAMGLEASDCSFLWIVRSPNAHGMSAASGSPEPVTEFLPLGFEERMKGRGMCYSGWAPQTRILKHPAVGGFLSHCGWNSTLETVCTGVPMLAWPITAEQHLNRRFLVDTVKVAIELKGNSYTKEELEGDVVRPARFIPKEEIEKKVRILMQDAEGESVRQNMQNLREKSREAGAPDGSSRRNFEAYVNLLHKKIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTZ6</accession>
    <name>A0A8T0GTZ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G095500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045277">
        <property type="entry name" value="DRE1A-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839:SF2">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="9">
        <location>
            <begin position="241"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="502" mass="56044" checksum="D4EC9B1649252801" modified="2022-10-12" version="1">MALAIDTRYLLERWIPDQEDYLDAYAGSKGRFQLHRVCAHATVVHNCSTIKPRHFNQDVEQAALNWQADPDDDLHEVEVFHHLKQLAATSPLIPELPQQYANRTTLVASVQSPTFLARMQGLPPNCSYHRYSVKMIMEDKGNGHTYGSKTTLSEVIPDVARRGRLWACVNDPKIVWASTADHCDLLLVWHIQLDFVDIYSPRIHPDSSPSKRRRTLNSFQQVPSCSEEDISPESSLPEVKRFKGVRYRRERRTWVAEMKPPKSRNKFSFGDFKTQTEAARAVDAAFHYFGKPLNFADTPQILSTLPTATGLNEEAKLKHVKQQAKWLASIVSTLPSSPILPVTSAGASAESEPFEISESSTICTSGFRSFSEITSALSCGGTDEADDGVSQPDPMASFVVNEVEDMEPNFTATDHGCVVNEFEGSQSMVIIDPCDTAIGPEYSTGTRSNFLSSSGVEQPYKIQRMCMDFLILSPPAPTLQMRSPRTRHGDAADVLWSSRNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVP0</accession>
    <name>A0A8T0GVP0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">E2F/DP family winged-helix DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G055600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the E2F/DP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090575">
        <property type="term" value="C:RNA polymerase II transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000073">
        <property type="entry name" value="E2F transcription factor 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000295">
        <property type="entry name" value="E2F transcription factor-like E2FE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015633">
        <property type="entry name" value="E2F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003316">
        <property type="entry name" value="E2F_WHTH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081">
        <property type="entry name" value="TRANSCRIPTION FACTOR E2F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12081:SF7">
        <property type="entry name" value="TRANSCRIPTION FACTOR EFL-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02319">
        <property type="entry name" value="WHD_E2F_TDP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01372">
        <property type="entry name" value="E2F_TDP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="11">
        <location>
            <begin position="115"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="E2F/DP family winged-helix DNA-binding" evidence="11">
        <location>
            <begin position="257"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="205"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="205"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0563736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="674" mass="73632" checksum="98A3812D54DEFE15" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXF5</accession>
    <name>A0A8T0GXF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Profilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G104900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the profilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXF5"/>
    <dbReference type="OrthoDB" id="421374at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005938">
        <property type="term" value="C:cell cortex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003785">
        <property type="term" value="F:actin monomer binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00148">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.30:FF:000001">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048278">
        <property type="entry name" value="PFN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005455">
        <property type="entry name" value="PFN_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036140">
        <property type="entry name" value="PFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027310">
        <property type="entry name" value="Profilin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11604:SF0">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00235">
        <property type="entry name" value="Profilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00392">
        <property type="entry name" value="PROFILIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01640">
        <property type="entry name" value="PROFILINPLNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00392">
        <property type="entry name" value="PROF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55770">
        <property type="entry name" value="Profilin (actin-binding protein)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00414">
        <property type="entry name" value="PROFILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0564366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="14304" checksum="A870C5FF05278DDC" modified="2022-10-12" version="1">MSWQSYVDDHLMYEISPGHSLFAAAIIGHDGNIWAQSATFPELKAGEIEKLLDGFEENSVLAQNGLFLGGHKYMVLQGDPGIVVRGKKGPGGCCVRKTNSALLIGLYDEPCTPGECNIAVEKLGDYLQEQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYD6</accession>
    <name>A0A8T0GYD6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G042600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45687">
        <property type="entry name" value="AQUAPORIN OR AQUAGLYCEROPORIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="269" mass="28355" checksum="DEC2DA7080F12705" modified="2022-10-12" version="1">MANEERPKTLAEAEAPAPLVDRKEVSDWSFYRAIIAEFMATLLFLYISLTTLVGTIRVGAGSVGLIETAWAFGGMIFILVYCIAGISGGHINPAVTFGLFVAKKVTITRALAYIVAQCLGAMCGAAIARGVQGSEEFHTYGQGAVNGVKPGHSIGQALAAELMGTFVLLFTVLSATDPTRMARDSHVPVLAPLPIGFAVFVVHLATIPITGTGINPARSLGAAVANPLHGNWAQHWIFWVGPLAGAAAAAVYHTYVLKAGSIKFRSLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYN5</accession>
    <name>A0A8T0GYN5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G023500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYN5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12441" checksum="D67A12928F9D772E" modified="2022-10-12" version="1">MPKHFKQVLAPTSIQLHPCLFQPSSERSPRRCARAMIQPRNLEAEEPRLNPRASLKTRPLHTLGPQILGLQSENHQHVVKWAPASRTRISLSTISTKSKWASHRILALAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ04</accession>
    <name>A0A8T0GZ04_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G186600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36335">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36335:SF1">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="521"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="447"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="597" mass="64295" checksum="00DAC1D25F2FD6FB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1E6</accession>
    <name>A0A8T0H1E6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G090100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1E6"/>
    <dbReference type="OrthoDB" id="724026at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31439">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31439:SF4">
        <property type="entry name" value="NEURONAL PAS DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="632" mass="70623" checksum="A8813C6FDF16C03F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1P7</accession>
    <name>A0A8T0H1P7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G160600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1P7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15743" checksum="75D8176890FBB8A3" modified="2022-10-12" version="1">MSSPQPQPALLLLSKTSNSPTHPKRTLTKPRANSTLLLHTLEKLTSESAHSLPTASSKRKFLTSSSQIRNAEAHDPSIEQFRSIPTESGLLPCSPKFLIHLLDMANLRSSVSSATKQAHQCPETNIIYRKTTSKPQKSTKTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2J5</accession>
    <name>A0A8T0H2J5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G187400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2J5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="52"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="470" mass="53578" checksum="39B79FA59CF3EAF1" modified="2022-10-12" version="1">MALGLISRFVLKLDLLVKPELEHSFKGNLKFGRGLSCKEIVMAGPSLSSIHGVQQSNLPLDVMERVLSFLPLPVLCRMRTVCKEWNHIICSSSFHDCYEQTWEERGHGVCFSTKFHSYTRIDRSVRGTTCFLDLDERRWYLIKGSVDQGFDTRDVAMGDGLVAEFCCPVEDEDIKYVFGPPTVCCIQMSDPILKMRWRLNPYPNEDKDHSIVVVAVDRGSRVFRIFLFQNSGFGLICSHKCLWMYESSTNKWRCASQPPRKGSDNNAATSAVVFQQGLYAIFTASDSWGDSFLALYDIEKDTWSMVFENLPAVQRVELVVSSGKLFMFWRSASSTSSAMMLEMVEIQVSEKTYRTVFQIPASTLSHFFGEQINKYDFAITCLALRLNFNSSCSSVVLFSKSSGKVIIYNVVSATVDILPEHPLRPEHPLRETKLRNHRYWATHQNLCVRDILQKDAQSHALVYVPKEQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2U0</accession>
    <name>A0A8T0H2U0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G128600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2U0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="314" mass="34154" checksum="BDBDBED055342838" modified="2022-10-12" version="1">MGFKSVSSKERHSAPYRPDEKLARYGPGALATVKTMSICAKRMDGSLPLAHHFLLIDVWKIEKGASTFRNRCILAERTKVDRKFEIVVKEIDRDEEDERREDGTVKHAVDLTGNHEPIKIKVNELVDTLKQCVAKDYTLTKHNCWKFTHDGFSALILKITEISGDISTELKVKLDKALAEMPSLCLPNDAAPFVKSALCCFGVGIPVFGLGAYALPLMAGGMLGAKGVAFALSVEGLRAMAMKTLLTTNTTGVVLKAGIRFGLFLCQPGALSTALAGLSLTAGVCLVAVGAYKLTRAIQYGLARRRSRRRAVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3R0</accession>
    <name>A0A8T0H3R0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G026200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3R0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035760909" evidence="1">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5892" checksum="BE4DB1346E22C196" modified="2022-10-12" version="1">MLTIGASLVLLPLWIIIQGVVPKKDILTSSIQILTTSVHNRQMVKPGGRRRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3V1</accession>
    <name>A0A8T0H3V1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">THUMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G029500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3V1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016423">
        <property type="term" value="F:tRNA (guanine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000073">
        <property type="entry name" value="THUMP domain containing 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911">
        <property type="entry name" value="THUMP DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14911:SF13">
        <property type="entry name" value="TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143437">
        <property type="entry name" value="THUMP domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="THUMP" evidence="5">
        <location>
            <begin position="112"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="455"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="479" mass="52849" checksum="858B95AACE03040B" modified="2022-10-12" version="1">MAAVAHYWASCAGGLEFALLKELENLEGTSIIPGIDSYGGVQFRTTSAPQKVAELRSADNVYAFLSHHKKIPVDKESGMAFLGSLAGKIDWEPVMQLHRLWQETEEPDSSSGISDPLLTINGMANVEQTHVTPQRSFRVTGNRICKDMKKHGYTSMDAAAAIGDGMHELLGWPADMRSFNVEVLAWIIDDELLLVLALIYSGNKKKTKNLQNVSNINEPCAEVEDVEGSEQVKSTKKKRPAERPSRADAQLYSRRPYRKALVHTSLKPSTAYGLLQLADVQPGDIVLDPMCGCGTIPLEAINWLGTRVMGLAGDFVDTAVEAANINATAGESPGHCDVVRWDASMLPLRTASIDRVICDMPFGNRCGNHKVREVLCPRVVKQVVRVLRPGSGIAVLMAQSKTMKEEIEVNQKAYLNLQKHFYVYMEGLKVDVFVVRRTSEPAPTQQIVRPIKNMAKRKRDGQLTKQAALENLSSENPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H684</accession>
    <name>A0A8T0H684_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G136000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15568">
        <property type="entry name" value="PHD5_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000303">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.200">
        <property type="entry name" value="Plus-3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058668">
        <property type="entry name" value="NERD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004343">
        <property type="entry name" value="Plus-3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036128">
        <property type="entry name" value="Plus3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46695:SF5">
        <property type="entry name" value="RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46695">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25980">
        <property type="entry name" value="NERD_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03126">
        <property type="entry name" value="Plus-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00719">
        <property type="entry name" value="Plus3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159042">
        <property type="entry name" value="Plus3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51360">
        <property type="entry name" value="PLUS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="7">
        <location>
            <begin position="410"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="DM2" evidence="11">
        <location>
            <begin position="639"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="domain" description="Plus3" evidence="10">
        <location>
            <begin position="779"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="domain" description="GYF" evidence="9">
        <location>
            <begin position="1179"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="1383"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="5">
        <location>
            <begin position="1383"/>
            <end position="1408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="35"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="571"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="960"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1248"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="571"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="614"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="763"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1023"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1069"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1318"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0567456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1408" mass="156159" checksum="C45B0C7A474BB151" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9W2</accession>
    <name>A0A8T0H9W2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G021400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9W2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="48"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0565892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="53877" checksum="32D9B1BA5C9CF1F9" modified="2022-10-12" version="1">MQAGEIGLNPEPLAGNYGEMEEQNQRLESERNIPDPTMKGKVSRLLWHGGSVYDAWFSAASNQVAQVLLTLPTSFAQLGYPSGVIFQVFYGIMGCWACYMIAWLYMEYRTRKERQGHSFKNHVIQWFEVLDGLLGPYWRLAGLAFNCIYCLFGSVIQLIACASSNIFLLNDHLDKRTWTYIFGALCMSTVFIPSFRNYRLWSFFGLIMITYTAWYMTIAALIHGQVPGVQHEGPVSKVLYFTGATNILYTFGSHAVTVEIMHAMFKPAKFKKVFLWATLYVFTLTIPSAISVYWAFGDSLLTNANSLALLPRDIARDIAVVLMLIHQFITVGFAITPLYFMWEKLIGVHQTTNLLFRALCRVPVMLPIWFLAIAFPFFGPINSTVGALLVTFTVYIIPCMAHMVYFRSAAARSSSVEKPPFFLPSWTGLYIVNIALCVYIVVIGIGFGGWASVTNFIKQIETFGVFAKCYQCPKTNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBE4</accession>
    <name>A0A8T0HBE4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G064600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBE4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="58431" checksum="730A5A950B68F47A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBR0</accession>
    <name>A0A8T0HBR0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">2-(3-amino-3-carboxypropyl)histidine synthase subunit 1</fullName>
            <ecNumber evidence="4">2.5.1.108</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Diphthamide biosynthesis protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Diphtheria toxin resistance protein 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_7G147000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11850:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF1">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="469"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0567599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="497" mass="54200" checksum="C95E9B32334F45E0" modified="2022-10-12" version="1">MESGKEATGATQAITKTAGPPRRYVRQQIPDSILNNAALKAAMAVLPSNYNLEIPKTVWRVKQAGAKKVALQFPEGLLLYSLTICDILEEFAGVEECFVLGDVTYGACCVDDYSAGALGAEFLVHYGHSCLVPVDVSQIPCLYVFVDIQIDVAHLVGSVKHNFEAGTKLAVAGTIQFSTAIQAAKAQLVSDFPHVLIPQAKPLSPGEVLGCTSPALPDGTVDVIIFVSDGRFHLESFMIANPKVKAYRYDPYSRVLTYEKYDQKGMREARRKAIEEAQLSKKWGVVLGTLGRQGNPQILKHLEKRLEARGIQFITFLVSELSPTKLAMFKNSIDVWVQIACPRLSIDWGEAFPGPLLTPYEVEVALGYVKPWWVAKGWVEGTQPQNRRLSSIQKMAAADSDSVEISESSNGTSERELLPVAVAESHSKEEMNLAEDSATKESEVVDELEVGPYPMDYYARDGGPWNSAYQRGPVSSRRAGAGTKISPQSAGTVISIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC56</accession>
    <name>A0A8T0HC56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G005900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16259" checksum="E07DC2C9A800EBC6" modified="2022-10-12" version="1">MLSYPAAFPYLELTPTREEKGKEKIKDRGPRELKGFYACQLQSDRAQVNISPHFLEPVHARRKTSTAEHARPATTNKLRHQHFILDHRSSWRGPALSTTDRSPVSEIHQVQKHSPTNHSPATTPQCMSIGYPTFLHLHSSTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCE9</accession>
    <name>A0A8T0HCE9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G163800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21752" checksum="F46E7CBF3DCF13CB" modified="2022-10-12" version="1">MEIIEYTTSVKNQQQPQCPPPTPRSTFPTLLCSIPVHRFSSLPHHPARLIHPPHRPIHPCRGGGPGRDVVKFCQSVGSKQSTDQTRAEHRSEEKSREQEWASIWQPWLRETRREEPIYAHWAVARVTHSHGAGLRVYFLALLNRVSLRFGRGGWDCGATADSEGSERRQDRRSGRFPRSANSVVAMEGGGCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF28</accession>
    <name>A0A8T0HF28_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Seipin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G157900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140042">
        <property type="term" value="P:lipid droplet formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23995">
        <property type="entry name" value="Seipin_BSCL2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009617">
        <property type="entry name" value="Seipin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212">
        <property type="entry name" value="BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21212:SF0">
        <property type="entry name" value="SEIPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06775">
        <property type="entry name" value="Seipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="370" mass="42370" checksum="266F61F02409A3AB" modified="2022-10-12" version="1" fragment="single">MYLLFKGVTYPFKLVLKLILYLVYILKLLVFGIIKPFKMLKNITFLGVSNIRSRILKHSQNGCNINQGYHGCGCATKTYILIVLSSLLLPSLFDLDFYLVNRFIEGQVVIREALNFDYTKDHPTAMVNLLPQQIIGKAKGYFPDREVMATHAFPPSHIYHVIVHLTLPESQYNHEIGMFQVVAETFSTRGHSLNKESRASMLRYHSPPVKYMKSIIMGIPIVLGISQESQTLSIRVMESQNENEHSPTASVRVDIEPKAGHLTGLGVPEIYHGELQVIAHNPYLREVARNWVWSLYVYSGIALFVFEALLVLCCCRRIFPQKVTKNDISEGFLNKERKLTFKGGPKNMQTLKRLHRQYYYYSKSLPLALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG57</accession>
    <name>A0A8T0HG57_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G092700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056813">
        <property type="entry name" value="GIL1_IRKI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24994">
        <property type="entry name" value="GIL1_IRKI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="246"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="545"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="900" mass="101630" checksum="BE66DC29944CDDF6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGL5</accession>
    <name>A0A8T0HGL5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G074400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGL5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035771465" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5517" checksum="E5FD76C60C13A0AF" modified="2022-10-12" version="1">MPSSFSFHGRILVSLILQLELAQLKLFSVLNLGHWESLEVASDHNSQSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHW0</accession>
    <name>A0A8T0HHW0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G159400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0052">Apoplast</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035958619" description="Germin-like protein" evidence="10">
        <location>
            <begin position="35"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="11">
        <location>
            <begin position="82"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="44"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0570398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="235" mass="25036" checksum="44EACE2E59D0B16E" modified="2022-10-12" version="1">MGSYRTQRSTHDLLKLLVVALCASTAFFLSDVHAADPDPLADFCVADLSPNAPLVNGYACKPRTNVTTDDFVYTGFRQAAASDAQIRQAPTGAVVSLAGPKEWPGLNTQGVTHARLDFAIGGVIPLHTHPRAAETLLVLKGTIYTGFISDDNVLYASTLKQGDVILFPKALLHFQLNVGNETAITFNTLTSQSPGLLLSANQIFEPNITSAVIEKSFGIDAATVKLLKASYPGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIH3</accession>
    <name>A0A8T0HIH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G166000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035733623" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="8063" checksum="84FD830B662E7038" modified="2022-10-12" version="1">MLLLLLLLLLLTPHFSWGSYLVHCMFPNTSSPHQTNNSAFPSTIYTICEKFWEAIVENSGFDMLRIGFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIR7</accession>
    <name>A0A8T0HIR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Poly A polymerase head domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G185100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3090.10">
        <property type="entry name" value="cca-adding enzyme, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052191">
        <property type="entry name" value="tRNA_ntf/polyA_polymerase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43051">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43051:SF1">
        <property type="entry name" value="POLYNUCLEOTIDE ADENYLYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81891">
        <property type="entry name" value="Poly A polymerase C-terminal region-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Poly A polymerase head" evidence="5">
        <location>
            <begin position="107"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA nucleotidyltransferase/poly(A) polymerase RNA and SrmB- binding" evidence="6">
        <location>
            <begin position="263"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="551" mass="61422" checksum="C7FB415843CED140" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ16</accession>
    <name>A0A8T0HJ16_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G177800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ16"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="10829" checksum="BD557A97682A9B1E" modified="2022-10-12" version="1">MGCHRLLQKHDMDAGRVCGPPAPSVQSANPTIASLARSSIDCCALLHAIANNSTALPPGSRANSSSCLLPSDARSRCAELLLRLEFAASASFSYELELGVQFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJA1</accession>
    <name>A0A8T0HJA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G193100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770955" evidence="1">
        <location>
            <begin position="16"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5852" checksum="0DE209D38E720A50" modified="2022-10-12" version="1">MITILLCLGLLYCNQNPIMIGHPLDWCRNCCHSLWRMWRCPCLLCQTASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMJ8</accession>
    <name>A0A8T0HMJ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG049700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11323" checksum="94071005FAADD15D" modified="2022-10-12" version="1">MFGLPNVCSGIPSLEFTHLKLGNASGPPSEEIKNKNRVMDSCSYSSNERELKCGLHPIIAYSPASRPSLSEAEVQTESLVIKLKERESHLSGHGPYRIDRIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNG4</accession>
    <name>A0A8T0HNG4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG086700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNG4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16898" checksum="3015D4FD53D567FF" modified="2022-10-12" version="1">MDPGWQTKVVFGKDIVRCTISLPSVTFRYHVGRLVLYSNFKYRRERLAQDGVTSEQIDQVREEDMVVLPCFFQGLSVARFEVGRGWPLSHIRREVAITLGDVAPEEFRFVLKQVGYPDVKVNRRHEGSNTVSQVLPPWTFEIVALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPZ9</accession>
    <name>A0A8T0HPZ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG130900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="314" mass="34354" checksum="460E73436CAB0CC9" modified="2022-10-12" version="1">MTGSSGGHRLVRKKYKGRGRLNKELVGEERRIERGRRKGSSKEMGIRDKRRSHKRRSASKETADVSKGAPVSDEDDCTEEDSPLQKRFRKSKAAEDEDLEACSEPEHAETTSPVTATPTAVDRDGDVALPLVVDLEYEESTGVTAVGGTDAPGVAVYEAEAPRATKGMLEKETSAIPASPNQRRRLDYWDANSAVILLSRNSVDWEDTPPHSLHVGTDSQHEVSHLGQAHIQADVVGQLQMTARSAACQWGRDTVAVDPHIGVTVAALVGEKDVLVENKFHDCIMVGSVTKARTCCKLVHICSELLWRSILGRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQQ0</accession>
    <name>A0A8T0HQQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG149700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5481" checksum="6113C46AFC6220FE" modified="2022-10-12" version="1">MLILHFDLLRRLVALPSVLPSSECCSSLHPLQSLIRLVECGRQPPLAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTF2</accession>
    <name>A0A8T0HTF2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG208900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTF2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035712458" evidence="2">
        <location>
            <begin position="21"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="134"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="172" mass="19433" checksum="46A122689758E22C" modified="2022-10-12" version="1">MPSHAFFLSLILPCQECALSSSPPSQTISSLKTNIFNTSTTQAPTTIAPPRNPIQLNTKPNSQANLPSKPKTNSQKPTLSRKKQSNHLPTHKITKPNLQPPKSTLTHENPPFHKQSKPTKPKIHTHSFKPTKPHPTNQPTNQPTNQKKKKKKKKTKQAYLTWSCKRRLQRHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTV7</accession>
    <name>A0A8T0HTV7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG221500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11146" checksum="242135426EE265AB" modified="2022-10-12" version="1">MENSAPSSSGTPVPPEAQTISVHQVVSFSEFEQVQEVRQTVDIGPGLAGSVSQSVQARKRGRPLKDAVHGGATTNVQGRRRGRTRESTTSSVVSGQTTALENLSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV58</accession>
    <name>A0A8T0HV58_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG261000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="13245" checksum="E9D5218EFE81569A" modified="2022-10-12" version="1">MKIFHFGFNQTMVNAYVMWVKDIEALGLSASTHLAFKISVGRHLAEDAINARQKLRCPLGPAPRRRHPVHTLYQSDLKWQCVVCDCLQKWLCRPCGNKWMCLEECYWAKHERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVH7</accession>
    <name>A0A8T0HVH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG295400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="11739" checksum="9A472E3C7EA42598" modified="2022-10-12" version="1">MRHPCSNFRSWLMQLGFAELGVQVLERLECRLEAVLVAAQWARIVRKESMQRVQWRRLQPLERRRWRRRRRRKRLWRRQRSKVHPCSKLWVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWN9</accession>
    <name>A0A8T0HWN9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG319400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8109" checksum="FF9269F932221E22" modified="2022-10-12" version="1">MFSVIRCRIKYLCLLFLQASKTGLKLSYFRVLGLTSGEPQPTDRKHYILNNSKSASHIEISIPAHRFGKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX68</accession>
    <name>A0A8T0HX68_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG313800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8110" checksum="31E23D3477D15C63" modified="2022-10-12" version="1">MATSFTEGQTSRLIADTKLISKIANLLYSLPWTARSSATSFAATIVFPELIMRRFGFIVDAACVAMSYTRIANT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXY2</accession>
    <name>A0A8T0HXY2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG328800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXY2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14830" checksum="9774B80CA512A3CE" modified="2022-10-12" version="1">MEFLVDTHHQSRQRAPLSSHSSKMQPQPNPNLVIQNPSRATKRAPGKTYLESETVRYHMARPRHAPAHGIRCGDMACELSRPRRRALGVCGDGACSKRNLGGNANEPVHSASLAGIVPCLFVCLGCVELFFRISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYB4</accession>
    <name>A0A8T0HYB4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-acyltransferase</fullName>
            <ecNumber evidence="8">2.3.1.225</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Palmitoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G029600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 8">
            <text>L-cysteinyl-[protein] + hexadecanoyl-CoA = S-hexadecanoyl-L-cysteinyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:36683"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11032"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57379"/>
            <dbReference type="ChEBI" id="CHEBI:74151"/>
            <dbReference type="EC" id="2.3.1.225"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The DHHC domain is required for palmitoyltransferase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the DHHC palmitoyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.225" evidence="8"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYB4"/>
    <dbReference type="OrthoDB" id="9909019at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019706">
        <property type="term" value="F:protein-cysteine S-palmitoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001594">
        <property type="entry name" value="Palmitoyltrfase_DHHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039859">
        <property type="entry name" value="PFA4/ZDH16/20/ERF2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12246">
        <property type="entry name" value="PALMITOYLTRANSFERASE ZDHHC16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01529">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50216">
        <property type="entry name" value="DHHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Palmitoyltransferase DHHC" evidence="9">
        <location>
            <begin position="152"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU079119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0575767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="39365" checksum="4BCDBBE8F5821C38" modified="2022-10-12" version="1">MGLAVDGNETKMPVQELPVGWETSCWGCGLRVVLPKFAPMFKCGWCGAITIEKSEMKPISPWSRRCSKGRDRVFVCLVLCLTFSIVFGGVWATFPVLFPTATVGFYVHSVITIVLSFNTLFNYCMAAFRLAGPSPRTEYGKFDLVDKKTLEGYKFCVYCKIPKPPNAHHCRSCQCCVVDMDHHCPFIGNCVGANNHQHFLLFLLFASVSGLYVLTMSTYVGTIVWPQLLRFRRVNLPRVHAGVSFDVVLDVLAAMVVSLEPVASTRAFALIYLFIASLSLVIGVGLLLYQQVQLVYTGQTYLGTLTSGSGNHHLVKSWTNFRRLFGKQHPFFWLLPRVGLNYVPPSEKIHTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYI7</accession>
    <name>A0A8T0HYI7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FLZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G033900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FLZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007650">
        <property type="entry name" value="Zf-FLZ_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33059">
        <property type="entry name" value="FCS-LIKE ZINC FINGER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33059:SF4">
        <property type="entry name" value="FCS-LIKE ZINC FINGER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04570">
        <property type="entry name" value="zf-FLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51795">
        <property type="entry name" value="ZF_FLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FLZ-type" evidence="7">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="FLZ-type" evidence="5">
        <location>
            <begin position="242"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="85"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0575827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="306" mass="32831" checksum="BCC10E68CDED5F46" modified="2022-10-12" version="1">MTGKRPRALTRTASVSQLGSAGNLSQEFSPLLENPKEKLKPTIKESSPAPAACAPRVVIGFDPKPSGHGFEGGECGVASPKSAPCSPSFQDKTSSPRSVLNSLFSRQRVKTTGEGVGLGIVLQPAAVSEIGVVEKVDHIVVCVGEDIGPLQRVREIPVSQPRRHSHPIPTPGISPCHFSHQASKQVEAKVVASVSERPVARPVLGWLEQEVDRRDTFLLAPSPARSLVGDHNVSAALTASSHFLDECSFCKRHLPKDKDIFMYRGDKAFCSVECRSQQMVLDERSKNCSSSALKRRSVVPSTVAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0W7</accession>
    <name>A0A8T0I0W7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G091000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0W7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805286" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7747" checksum="0C7ADF531EB036F9" modified="2022-10-12" version="1">MSSFNGWCALGCTWLIQVWLSRQEFVNSERKYNSERKYRSTLVYQHQNRCGLNTSQSGPYILVLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0X9</accession>
    <name>A0A8T0I0X9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_5G089000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0X9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000002">
        <property type="entry name" value="Sulfate transporter 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="376"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="8">
        <location>
            <begin position="525"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="656"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0576555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="699" mass="75998" checksum="F028D73C6A7DEC0B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I420</accession>
    <name>A0A8T0I420_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G009500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I420"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="379" mass="42903" checksum="FD7092B30FF79B89" modified="2022-10-12" version="1">MLAIEVELPHETKTIEWKKAHPTFHELKIRLQQCGIATNKNCCIEVEKAQEFLTPDDDDLLDGPLIRVRAYQIICNTPWKRPRLDEPPKKDRPNVGKMPKTYHNRYEELFEEEVIPFVGRIFVLPKKFDDISLQDCIGTVGLVGPKGESVGAFHLVQKAWKHPRRYDVYIKYMNHDKQPCFPAKVVTYNDELDIFVATPLPPFEFNFPKFLQLASGIAVGDSVHCVGFPNLVNETILSQKEKFAGNNVFEQCVKDSDLGFPSVFTGNVCFPGWKQVLADYRSFSNSSGAIIVDNNGHLKGIHMSSLRAAEYVPELSELEPNCKTSDKTKALYEQVNKCSLQLMLQVKCNTEAAVFVPINILMKIINPAVNPTSRAILYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4P4</accession>
    <name>A0A8T0I4P4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G032200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4P4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9969" checksum="900FA03F8B8FF5B1" modified="2022-10-12" version="1">MSSPEVLGISGAKKEPTEQRSTWIVWEVRLSDWFGTRVCKFCAFTFNAFASCTYRWCSKLDLLAALILARLLPWRRLSQLTHLCQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I552</accession>
    <name>A0A8T0I552_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G046700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I552"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13710" checksum="5CEEA9B756AB8965" modified="2022-10-12" version="1">MLALHVKRIANPAKEKKGRAYIFTFPRINSTKAPARPLMTREVTGNSQRKCLHCQKGQEPGAYARNFVRSSVSTLSACFRSSTSQAPQLQVVYQPSPPRTGKFFHLLKPKCDDTIANKSEMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5H6</accession>
    <name>A0A8T0I5H6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G015800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 13">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5H6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13983">
        <property type="entry name" value="STKc_WNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000075">
        <property type="entry name" value="Probable serine/threonine-protein kinase WNK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000046">
        <property type="entry name" value="probable serine/threonine-protein kinase WNK9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024678">
        <property type="entry name" value="Kinase_OSR1/WNK_CCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050588">
        <property type="entry name" value="WNK_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13902">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12202">
        <property type="entry name" value="OSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="35"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="341"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="493"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="566"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="653"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="514"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="573"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="599"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="667"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0578346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="877" mass="99855" checksum="0548EA5D15A53F4F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I800</accession>
    <name>A0A8T0I800_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G032500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I800"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018958">
        <property type="entry name" value="Knr4/Smi1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051873">
        <property type="entry name" value="KNR4/SMI1_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47432:SF1">
        <property type="entry name" value="CELL WALL ASSEMBLY REGULATOR SMI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09346">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00860">
        <property type="entry name" value="SMI1_KNR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SMI1/KNR4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Knr4/Smi1-like" evidence="1">
        <location>
            <begin position="43"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="22601" checksum="B27F1BD67B3B6FB0" modified="2022-10-12" version="1">MSSGYCSSKREMESITVQWERIEAHLRSHPALDESSKPFLNSGATEEEIVAAEAAVGVRFPEDFRASLERHNGQAREEVLLGMGALLSTREIVEQWGVWNELLEGGSFEEDFCSKPEPGVKANWWNSRWIPVTHDGGGDHDCIDMDPAEGGTVGQIIEMWHDDDIRPLRAPSFLSWLTAAASGLEDGTLVWEEGVGFFPKQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I877</accession>
    <name>A0A8T0I877_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G085000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I877"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14662" checksum="392F6C271912AE2D" modified="2022-10-12" version="1">MEVEITPDLQITNEERTKQKAFVTPRARVYVKDISMAQFDISLGTKCHFIPRKPKQYQTHQNNPTQRLHSESETEVHFNLEIFHLGTSSELKDQHLTQRQLYPKKAAPVQTENKAGLHHARPNSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAQ9</accession>
    <name>A0A8T0IAQ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G108200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035854182" evidence="2">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="14261" checksum="E0F90F6D5C6CC878" modified="2022-10-12" version="1">MGINMKGLVCTLLLCGLVGALAASSSGEAGEGQDLKNHYLRGTEPKMVDGKKFKFCSPPPVDYPPPYVPPYSPPYSPTPDYSPPYSPSPDYKSPPYSPSPDYKSPPYSPKPDYKSPSPPYKSGASNTAPTPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC59</accession>
    <name>A0A8T0IC59_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G172800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035903653" evidence="2">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8291" checksum="5F5344D8EC75773C" modified="2022-10-12" version="1">MVCLLYCLGHILLSGSVLSLDSEGQEVFADVRFALYVIGVFLYWLDLVSLMVMGCICHFCESSHLALQMFIVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICQ3</accession>
    <name>A0A8T0ICQ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G187600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICQ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15094" checksum="AA2AC0C426B949C7" modified="2022-10-12" version="1">MGIFRSGFVSVMFIFLMVSLFCYVEGRSRLSHDLHEGSGVGTRVLPSDHPFSDHEIDPGYNSGRKMFAQRSAVAEEFASSKNDAEGQESMDSAPAAASSTRKRLPFHTQFVSKFPFFNFAKDNSTVTPAPGTPSPGHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID09</accession>
    <name>A0A8T0ID09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GYF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G268300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd00072">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003169">
        <property type="entry name" value="GYF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035445">
        <property type="entry name" value="GYF-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46992">
        <property type="entry name" value="GYF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46992:SF1">
        <property type="entry name" value="GYF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02213">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00444">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55277">
        <property type="entry name" value="GYF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50829">
        <property type="entry name" value="GYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GYF" evidence="2">
        <location>
            <begin position="721"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="537"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="913"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="941"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1046"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1238"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1387"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1453"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1517"/>
            <end position="1660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1674"/>
            <end position="1901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2083"/>
            <end position="2150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="494"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="650"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="793"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="947"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1390"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1518"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1556"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1569"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1597"/>
            <end position="1607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1608"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1620"/>
            <end position="1633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1682"/>
            <end position="1699"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1743"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1785"/>
            <end position="1800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1812"/>
            <end position="1828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1876"/>
            <end position="1890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2175" mass="237836" checksum="CF500371911AE600" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFA5</accession>
    <name>A0A8T0IFA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G060300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967:SF57">
        <property type="entry name" value="AUXILIN, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22967">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="29"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="299"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="442"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="562"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="515"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="332"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="411"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="608"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="654"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="664"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="697"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0582444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="730" mass="80473" checksum="275BDF71985E9B92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH38</accession>
    <name>A0A8T0IH38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G109700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="325" mass="35051" checksum="E3C7C056417FBD59" modified="2022-10-12" version="1">MLEEEEGVDEYEAPRPAVLQAERVRARPRHSLPRRLARAARAALQSHFPSLPPLKVAASSRIPLAPERATGLFRSGALETHIARALGNTVGLDGITSAKQESLKLFSAVKNLPGAVTHAVGSKDEGFLPLQLSTKHPLGPTTVCETTIHGTKVSLLELQLRMVHTLINPQHSDQAHPKPAGRIALVTGTDLQSRHRLTMESTLGSEEDKHSLSTVVSSDLHSRLSWGVSSSLNVNEKLVIFSRYNNDAHAGQRIIFQAVNKVDKRNTISPICATTLGSVTQGGVSWTRSFSQTGVSEESIQVKALCSSNGSYMVSVKAQLGEVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH42</accession>
    <name>A0A8T0IH42_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Plant heme peroxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G106100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31235">
        <property type="entry name" value="PEROXIDASE 25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0349">Heme</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035879341" description="Plant heme peroxidase family profile domain-containing protein" evidence="13">
        <location>
            <begin position="34"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="37"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="47"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="80"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0583060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="14155" checksum="979554DABD07A503" modified="2022-10-12" version="1">MGRFGGGASPPGFMLQLLLVVLSVAALTSTAQAAKAQLVPDFYKSSCPRAETLISSAVNSALNRQAGAAAGILRMFFHDCFVHGCDASVLIDAPGSERSHPANTGLHGFDVIDAAKAAVEKHCPGVALVENRVFSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHU0</accession>
    <name>A0A8T0IHU0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G126800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Potassium transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053952">
        <property type="entry name" value="K_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053951">
        <property type="entry name" value="K_trans_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00794">
        <property type="entry name" value="kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540:SF83">
        <property type="entry name" value="K+ POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="OSMOTIC STRESS POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22776">
        <property type="entry name" value="K_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 10" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="418"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="447"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="511"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter integral membrane" evidence="12">
        <location>
            <begin position="23"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter C-terminal" evidence="13">
        <location>
            <begin position="525"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="664"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="673"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU321113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0583320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="797" mass="87837" checksum="08D4D4CD79CFFFCB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II49</accession>
    <name>A0A8T0II49_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RIN4 pathogenic type III effector avirulence factor Avr cleavage site domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G135800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008700">
        <property type="entry name" value="TypeIII_avirulence_cleave"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05627">
        <property type="entry name" value="AvrRpt-cleavage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIN4 pathogenic type III effector avirulence factor Avr cleavage site" evidence="2">
        <location>
            <begin position="123"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="209" mass="22709" checksum="58C9CAC1645BE7F3" modified="2022-10-12" version="1">MAGDKAVVAKAREVERDIVLKAKVEALQMEYSNVSSPKVPSSASDTPRASSVATPKGSVKSSARSTPAPRKYVSPMARAREEKKRREAGESNKSKDWPCLSDMESSSNPSTSGSLHSDMSTTKPANLPKFGEWDKHSVNSGPCYSILFQNAAQEKKIGGPVRIHSTQPNSPPRTQDLYQALPPATTKSTKKSKTTKKKKQFSLFCCFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIN0</accession>
    <name>A0A8T0IIN0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G051900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="225" mass="26094" checksum="C77C9582E57CA5C5" modified="2022-10-12" version="1">MASVFEAAKCRRQFVVAASPLGKCSPAPRICGTCGDKWQIRFFLVSKFKVSFLTSHSILPFRSESRHRIREISQISKTRNFQHHSDISKHFHHGRNIGLHIHAHGAQRTIRPTPNLQTTSHNLTHLRPPLPQPPHHHPLAHALPPPPSNSPARPRIQQRQRPRARLREGSGVRQGGRRRHHQASQRQERRGVRRRSGGQLRRGLLQQRRPSQRRRRRLRHGSRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJA8</accession>
    <name>A0A8T0IJA8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Stress-response A/B barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G132000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJA8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013097">
        <property type="entry name" value="Dabb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044662">
        <property type="entry name" value="HS1/DABB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33178:SF5">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07876">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00886">
        <property type="entry name" value="Dabb"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="Dimeric alpha+beta barrel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51502">
        <property type="entry name" value="S_R_A_B_BARREL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="14"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Stress-response A/B barrel" evidence="2">
        <location>
            <begin position="129"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="237" mass="26034" checksum="1BCCBA9C0B5D16F2" modified="2022-10-12" version="1">MSEVEMKPKTRKVVDHAVLFRMKDELTEEQEKEMLDALFTLQYQTKGVLYLSAGPVLGKTKDGVTHALFARFAKKEDVDAYMQHPGRVTIARDLVIPYYNGLVMLDVEDEVADDLEAIFGREFAQEGGIDHFVLFKVKEGTSQEAIDAMLQSFRDLAASLDPSIIFQLTAGTNISPVGKGYTHGLIARIPSDAALEAFVKSDGYVQALSKEALPDGTEFITADLPSAFRGSSVTLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJG9</accession>
    <name>A0A8T0IJG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_3G102600</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000952">
        <property type="entry name" value="Putative DUF26-domain protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000044">
        <property type="entry name" value="Putative LRR receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021720">
        <property type="entry name" value="Malectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11721">
        <property type="entry name" value="Malectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="637"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="701"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="729"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0583016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1055" mass="114071" checksum="D5452DC93A402E38" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJY8</accession>
    <name>A0A8T0IJY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G184300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="919" mass="101914" checksum="5971874CF23C4CC8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL59</accession>
    <name>A0A8T0IL59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit</fullName>
            <shortName evidence="8">Oligosaccharyl transferase 48 kDa subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G215300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the oligosaccharyltransferase (OST) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum membrane</location>
            <topology evidence="8">Single-pass type I membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the DDOST 48 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005013">
        <property type="entry name" value="DDOST_48_kDa_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055459">
        <property type="entry name" value="OST48_MD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055457">
        <property type="entry name" value="OST48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10830:SF0">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23358">
        <property type="entry name" value="OST48_MD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03345">
        <property type="entry name" value="OST48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035958416" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit" evidence="8">
        <location>
            <begin position="26"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 N-terminal" evidence="9">
        <location>
            <begin position="35"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="OST48 middle" evidence="10">
        <location>
            <begin position="302"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0584524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="440" mass="48898" checksum="2B7102B64E0DD19C" modified="2022-10-12" version="1">MASSSGKPLALLAAVLLLLPFLCAGFNPDSPTDRRVLVLVDDLAIKSSHSTYLQSLTDRGFELDIKLADDPNLALQSYGSYHYDALVLFAPKVESLGGSLDTAAVMDFVDSGHDLILAADATTSEAIREIATECGADFDEFHKAVVIDHVKYAITKFGSDHSLIAADNLIDSSVILGSEGIKEPILYRGLGHTLNPTSELGIKVLSASPTAFSGKVDAEITDLPNLIGSSISLVSVVQARNNARIMISGSLELFSNKFFESSVQQFGSENKYEKSGNQQFAVELTKWTFHERGHLKASNVHHHKIGETDEPSMYRITDNARYSLEINEWNGKEWQPYQADDVQLQFYMMSPYVLKTLSHDGKGLYFTEFQVPDVYGVFQFKVEHNRLGYTALNLAKQIPVRPFRHDEYERFIPAAFPYYGASFSTMIAFFVFGIVFLYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILL9</accession>
    <name>A0A8T0ILL9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G189500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILL9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035884005" evidence="1">
        <location>
            <begin position="37"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="16879" checksum="2EFC87C5589252B1" modified="2022-10-12" version="1">MGSVKQPQLAATSLLHILVAALLISQASLLLQPACARVVNADRRLLAATHDKVTKVVIDKEVEIVVNKVTPKEMEPVGKKETRTVANKETEMVATEDKPVGREYWGGGGGGHNYYPGHGGGGSYYPGHGGGGSGYYPGHGGGSGNWGGGGHGGGCCDDTENGKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN95</accession>
    <name>A0A8T0IN95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G171300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IN95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035806535" evidence="1">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6421" checksum="FFA3D385FF95D8CE" modified="2022-10-12" version="1">MAGRNHLLSSCLIVVQALQVLLVVLSCQHCTVGILTSIMYLAPFMESVHFIFCPRVCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INW1</accession>
    <name>A0A8T0INW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Structural maintenance of chromosomes protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G198200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family. SMC5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001301">
        <property type="entry name" value="Structural maintenance of chromosomes 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45916:SF1">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="8 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="12">
        <location>
            <begin position="35"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="305"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="401"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="634"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="759"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="829"/>
            <end position="884"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0584268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1063" mass="122208" checksum="D1D435F5035D1873" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPU7</accession>
    <name>A0A8T0IPU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">diphosphoinositol-polyphosphate diphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G036800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:79699"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:74946"/>
            <dbReference type="ChEBI" id="CHEBI:77983"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:79700"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3,5-bis(diphospho)-1D-myo-inositol 1,2,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:56312"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:140372"/>
            <dbReference type="ChEBI" id="CHEBI:140374"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:56313"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22384"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:58628"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:22385"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:79703"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="ChEBI" id="CHEBI:230534"/>
            <dbReference type="EC" id="3.6.1.52"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:79704"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein-tyrosine phosphatase family. Atypical dual-specificity phosphatase Siw14-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.52" evidence="1"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008486">
        <property type="term" value="F:diphosphoinositol-polyphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14528">
        <property type="entry name" value="PFA-DSP_Siw14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000024">
        <property type="entry name" value="probable tyrosine-protein phosphatase At1g05000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020428">
        <property type="entry name" value="PFA-DSPs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004861">
        <property type="entry name" value="Siw14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126:SF48">
        <property type="entry name" value="INOSITOL PHOSPHATASE SIW14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31126">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03162">
        <property type="entry name" value="Y_phosphatase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01911">
        <property type="entry name" value="PFDSPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="13"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="76"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0585764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="19710" checksum="4090B414C9FAD996" modified="2022-10-12" version="1">MGPEDELLIPPLNFAMVDKGVYRSGYPNTKNLPFLHKLRLRSIVYLCPEPYPEANVEFMEKNGITLFHFGIEGNKEPFVDIPGNVIREALKVLLDKKNHPVLIHCNKGKHRTGCLVGCLRKVQNWSLTSIFDEYRRFAGAKVRMLDQQFIELFDISTFKQTGRTLRFRVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQD3</accession>
    <name>A0A8T0IQD3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G236800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="161" mass="18296" checksum="8578782ED67945CB" modified="2022-10-12" version="1">MSYGFGLGWVMVLVWVMVWVMVWVMVWVWYGRHVADRSCRLWCGFGHRLGVASGELLFLLLSHAFSCWECFLLGTVQKSFRSEASYSRPASSGSSVPLLGSWSATVTYVGMLFGLEGEHCLTGSTNHLLLQTMSVKWLLFYLTEFVKWLLFLCNKCLSIVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQP7</accession>
    <name>A0A8T0IQP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G261100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="411" mass="46112" checksum="52CB86AEBD56D0F9" modified="2022-10-12" version="1">MAMAHEVIRARSEIYGVRDSVLFYHPGGKVLEAHVQIIIKILAHMNIPCLWDEFTDLEVNLAKEYKILFESCLNVPRLCAVLFGSSEAAISDKSKGSFSAVASRGAGVSEVPLPSMELLLAMLQHRKPNLNSYEIGSTFLRNFSVYGFNLSSHMEEDADVASLESIRAGGIHGVCFLTGTRLEALEQLASNRNKVDGISAYDLIRLEQNQYIEKRATGGHYDFRDPQLIGVTSVNSTLEDVEGYVFELLLRDFLKPQLFQFLIEKFPLLEGLEATEAQMIHGNLTKNCEIDGLIFYREYGIILSCKRSQGLQDWDKSFLDHLNHLSDEGKKQSPKVHRKLALCQRLFLVCVSVLDGETRGLPPSSYNHANLSLEGKYISEEKEISPLTIFLHDLLALLPPVKMAQSSCSWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX61</accession>
    <name>A0A8T0IX61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">carnosine N-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G169800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carnosine N-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.22" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030735">
        <property type="term" value="F:carnosine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012901">
        <property type="entry name" value="CARME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12303:SF6">
        <property type="entry name" value="CARNOSINE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07942">
        <property type="entry name" value="CARME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01296">
        <property type="entry name" value="N2227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="124"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="195"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="137"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0587509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="59518" checksum="CAEC038FF849F4B4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXR4</accession>
    <name>A0A8T0IXR4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G172300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in recombination ability and DNA strand transfer activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000087">
        <property type="entry name" value="Recombinase RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049261">
        <property type="entry name" value="RecA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049428">
        <property type="entry name" value="RecA-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900:SF6">
        <property type="entry name" value="DNA REPAIR PROTEIN RECA HOMOLOG 3, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="RECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21096">
        <property type="entry name" value="RecA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="RecA protein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="112"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="277"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="411"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="417"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="432"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00056887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0587538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="47925" checksum="DDEADED55427C13E" modified="2022-10-12" version="1">MPTMAGALRALRLRHSLLQRVCSACADPSTSYASLGTVDVSTPGYFARSAGFATDAKRGRRVKKPAEIIDADNPNLDLEYTKQKLIQAAIDQISKKHGKETVMWLGRESRDRVEVVPTGSLNLDIALGVGGLPKGRVVEIFGQEASGKTTLALHVIAEAQKMGKGHCLFVDAEHALDMQFAEGIGVRTKDLLFVQPDYAEQALDTVDHFVRSTGVDVIVVDSVAALVPKAELEGDMGDAQMALQARLMSKALRRLTHSLNSSQCLLIFINQTRSKLNTGYGGGGPSAEVTAGGNALKFYASVRLQVRKKEQLKRGDVPFGSAVIVKVVKNKVSPPFRTAEFDIEYGKGISREGEILDLGVKHGLLGQSGSWFSYEGKNFANGREGAKKYLQEHTDIADALVGAIKEKVLGKSRPTEDVEDEGFLHEDDDAFEMDHGDNLEGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXY1</accession>
    <name>A0A8T0IXY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G212300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050655">
        <property type="entry name" value="Plant_B3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920">
        <property type="entry name" value="B3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920:SF37">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR VRN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="41"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="229"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="39254" checksum="E61FA45A9F9707CA" modified="2022-10-12" version="1">MAETDDATVGSPIYVRWPLSLDEKPEVLRKLRSRIHFEKTITASSAAGYVGHHSRLALPFAFVKQHGDKFQKNVLLQTVLSSKAWPVRVEICFKSPGSSTKVKFSGGWRAFANFNGLQEGDSLIFRLAPMSKFKVYVFSSTRCSTEIPLQVKRKRISDSQIPQKKTGKQSHDGKDEQSSFDETTEDAAKSRELRMEKKTTTNSIAPLSTDVKTEVLRKLQGRIYFEKTVIASNASGSPSRDPTLVIPFQFLHSHGDKLRRSVILRVTSSSREWPVKLTTPPQLKFRGGWRAFAEFNGLLEGDSLIFLLTAVSEFEVYVFSSTGSPKKLPDSQSTTGSGSIHSRIHGSKCLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZY3</accession>
    <name>A0A8T0IZY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DEAH RNA helicase homolog PRP2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G202600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DEAD box helicase family. DEAH subfamily. PRP2 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZY3"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000594">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF83">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="420"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="608"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="99"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="168"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00077342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0587933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1051" mass="120318" checksum="DC0DF75A393444C4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1X6</accession>
    <name>A0A8T0J1X6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutaredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3 9">1.11.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G006300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62624"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:10730"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.25" evidence="3 9"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1X6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="83"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="248" mass="25651" checksum="0A9947CB368A6C7C" modified="2022-10-12" version="1">MASAMIASRVSAVAVCAGREFAPSVASKGAVVVPSLGVVVRRAHYGAAQTTLSSAWFGCRAGLKAVARFSSRSASVGRVVATISVGDKLPEATLSYFDKEGNVQSVTVSELTKGKKVVLFAVPGAFTPTCSNKHLPGFVAKAEELRQAGVDTLACVSVNDAFVMQAWGKSAGVGENVLMLSDGLGKFTQALGTTVDLTDKVEGLGVRSRRYSMLVEDGVVKVLNLEEGGAFTNSSADEILSSLQKASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J228</accession>
    <name>A0A8T0J228_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Zinc finger, RING/FYVE/PHD-type</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G060800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J228"/>
    <dbReference type="OrthoDB" id="1921166at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012866">
        <property type="entry name" value="DUF1644"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31197">
        <property type="entry name" value="OS01G0612600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31197:SF5">
        <property type="entry name" value="OS01G0612600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07800">
        <property type="entry name" value="DUF1644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="43659" checksum="3D0A8DE5B0896B39" modified="2022-10-12" version="1">MPKDRNVSRLSSGSQSSRYKPYSRYGQSGAQETCSTDGDDSAERKEWEEATCPVCMEHPHNAVLLICSSYGKGCRPYMCDTSYRHSNCLDQYRKAHELRDTLPSMSSVRGRAIAETERAVVNRVEDSEEDRGAAAAPAPAPGLVVRTLGAGGIGGEDRRETSVEVDGSRDGGLGQVSVEVGNNGVVPGEETDSGELLCPLCRGKVKGWKVVEAARSHLNQKLRSCAQESCTFNGPYEELRKHARCTHPSARPSEIDRTRLDRWIQLERQRELGDVLSTMPGATVFGDYVIEGDGNGDDEDGDDTDFPGDDGNWWTVFLLFQVFGQASMAGGRGLPASMVRGRFHPQRNSAARSALWGETLGGNNVNRLGSNPAGNSESNIGGGVGSRSHRRRSRERGRGHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J471</accession>
    <name>A0A8T0J471_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G091100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J471"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11857" checksum="7E6D16523B39A78D" modified="2022-10-12" version="1">MGQMAGGVAHENKPSASHPSFGRVSLPETTRDRNEFSRTRNRWSDELSRTTRKVPEARRYLPRVADHCGAHTPSSGFESLRAHSTAAYINTTTAHDPIIAVQSTSNAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4M7</accession>
    <name>A0A8T0J4M7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G070600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4M7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22159">
        <property type="entry name" value="F-box_AtTIR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000124">
        <property type="entry name" value="Coronatine-insensitive protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000023">
        <property type="entry name" value="F-box/LRR-repeat protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041567">
        <property type="entry name" value="COI1_F-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041101">
        <property type="entry name" value="Transp_inhibit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16134:SF43">
        <property type="entry name" value="CORONATINE-INSENSITIVE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16134">
        <property type="entry name" value="F-BOX/TPR REPEAT PROTEIN POF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18511">
        <property type="entry name" value="F-box_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18791">
        <property type="entry name" value="Transp_inhibit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COI1 F-box" evidence="1">
        <location>
            <begin position="28"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="Transport inhibitor response 1" evidence="2">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="592" mass="66501" checksum="41D810288B848AF6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6G0</accession>
    <name>A0A8T0J6G0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G180000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6G0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10253" checksum="57D161372FE6E85E" modified="2022-10-12" version="1">MYMLRGDICSYSPFQIVSFGVSEDLLDLAGFGELLYYTAREGPTIPPFGYSTLPSQDCISASNNKGNDKIPKEPRNPENWNTFTVGISRSHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7S0</accession>
    <name>A0A8T0J7S0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G195000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7S0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45942">
        <property type="entry name" value="PROTEIN PHOSPATASE 3 REGULATORY SUBUNIT B ALPHA ISOFORM TYPE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13833">
        <property type="entry name" value="EF-hand_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="80"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="121"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="17874" checksum="D4715EE11793E227" modified="2022-10-12" version="1">MGNSHSSRGLSKEEETRAKLRFERVTSKDQPFLSKRKFTDLLGNPTYAEGLFNLIDTDGDGTVSCKEICEEIKLIRASKTPGSKLRVLFSYYDSDHDGRISPSELASAMRVACGQDLSDSQLDKLVHSMMENFDVDKDGFLNFKEFCGLMRNAGLQYNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8N9</accession>
    <name>A0A8T0J8N9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G158100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8N9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21037">
        <property type="entry name" value="MLKL_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059179">
        <property type="entry name" value="MLKL-like_MCAfunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="184"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="604"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="875" mass="97996" checksum="E6B95AFF46BBE0F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB82</accession>
    <name>A0A8T0JB82_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G233300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12403" checksum="8270AE9E300B405F" modified="2022-10-12" version="1">MDNMYEKLSRALMRRKYEKVDRSRSVGNHRDGFVVKRKTVTVKIPKAEKGKEKVDDHGKDHVLETLPVVNPKRFTILSSGNDVVDEAWLAEALRRTLDEGRLEVLTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBL8</accession>
    <name>A0A8T0JBL8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G225100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBL8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="23723" checksum="E120FF5DEB9C6B02" modified="2022-10-12" version="1">MVAPNLCDQCKSHIASVRSSPCGSSKSTPRSCSNDNKPKDKPIYVKAETVENPCIVLDNGGGKCGGNISLQLPSPSSKLKFTCGGKSSSSSCIKIMGNSVIKTSNGGLQIIPCKGGGGNMQISMAGGRPVLQLGGGGGSSRQCGSSGGSGGGCPSGQLQLNFGKGGSPSITCGPSGSSLQIIYGPQKRKLDMNHCKPTIAHMIHKRTVELETELRMAECTYSDLHPSCDNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBU0</accession>
    <name>A0A8T0JBU0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G247100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant DMP1 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010256">
        <property type="term" value="P:endomembrane system organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007770">
        <property type="entry name" value="DMP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31621:SF66">
        <property type="entry name" value="PROTEIN DMP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31621">
        <property type="entry name" value="PROTEIN DMP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05078">
        <property type="entry name" value="DUF679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0592379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="20234" checksum="682D971A92F62016" modified="2022-10-12" version="1">MSSKKVVTDVLTQLSNVLPTGTFLVFQVLAPLSTNNGKCGRVEVVLTAFTLTLLCALCIASCFTDSYKAENGVVYYGFVTRRGLWNPNFKHALISGCEGSYYVGQVENREDNLKYQLEMDDFVNAALSGVALATFSLLTEPVTTCFYPGIQQSILKTVPLLVGLVIGAVCAFGTTPRNGIGFAMAPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC62</accession>
    <name>A0A8T0JC62_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G302000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="44156" checksum="9F140A4867E011C6" modified="2022-10-12" version="1">MASTGAAANAVIIIGAVLLLCSLHIDAKPRYNDVDNCGKCKHKCPRAPPHSERTCKNGKCGTKCKRGWLDCDQKKANGCEVDVKTLKTDVKNCGSCGNVCPVPLSNQFGTGVATCTKGVCGHTLTCATGFADCDGDPSNGCELDVKSNVNNCGSCGSVCPTGQLGQLATCTDGMCGLESTCAKDFGDCDSDPSNGCESDVRSDVKNCGSCGKVCPVPLTNHGSGEATCTDGVCGYTLTCAKDWADCDGDPSNGCEIDLAGIFSSIYNCGSCNHVCPPFQNSTIWSICDAGVCGYECNFFLGNLGNCDNDVSNGCETNLGSNDVNNCGGCGQVCTTPPRGQIACNRGVCTGNCLKGFYENCDRNPTNGCETSVWSDVNHCGSCGNVCPSPPNATPSCSFNTCKFTCNAGFSDCDLVASNGCEVHGVCPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCC2</accession>
    <name>A0A8T0JCC2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G271200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="9765" checksum="D032F0A2FB4899F5" modified="2022-10-12" version="1">MSIRLRMAQVAVHRQQLAAACCAHMCCASRVAAASDGDTGPSVECWSGGEAQRILDCCKVQFLQIFGVWAHQLLMSCVVFGTENHHWET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCL4</accession>
    <name>A0A8T0JCL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G280000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCL4"/>
    <dbReference type="OrthoDB" id="1915999at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04051">
        <property type="entry name" value="C2_SRC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044750">
        <property type="entry name" value="C2_SRC2/BAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246:SF143">
        <property type="entry name" value="CALCIUM-DEPENDENT LIPID-BINDING (CALB DOMAIN) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246">
        <property type="entry name" value="INGRESSION PROTEIN FIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="195" mass="21446" checksum="86C970F525EAA76F" modified="2022-10-12" version="1">MATTYREIELNIFSANDLRDVRYFGGKMSPYVVAWVHHDLKAYSPADVKGSTDPSWHTKLLVYCNEDALHHPDEAVIYFELHDAASTSDRLIGALSYPLSELPGHIASSKEPSEPVFLNLPVKRPSGREQGVLNISLKMGGVTQQPISSEDPHHVHHVQHGDGAMAPDDESFLAGCCGLPHFPRDEQVGSNVTAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD03</accession>
    <name>A0A8T0JD03_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G275000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035856076" evidence="1">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7687" checksum="5A0091F8E68DA586" modified="2022-10-12" version="1">MKPDICDVVLWFFFLFLFCSWDPQRAPLFRTFANLAETISYELNDFNGVYRARPLECCGNDSIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G573</accession>
    <name>A0A8T0G573_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Translocon Sec61/SecY plug domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G024000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G573"/>
    <dbReference type="OrthoDB" id="420669at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000002">
        <property type="entry name" value="Transport Sec61 subunit alpha isoform 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006341">
        <property type="entry name" value="PRK08568.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="419"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Translocon Sec61/SecY plug" evidence="12">
        <location>
            <begin position="42"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0553597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="477" mass="52653" checksum="16D323013D22E474" modified="2022-10-12" version="1">MGGGFRVLHLVRPFLSVLPEVQTAERRVPFREKVMYTVVSLFIFLVCSQLPLYGIHSATGSDPFYWMRVILASNRGTVMELGITPIVTSGLVMQLLAGSKLIEVDNSVREDRALLNGAQKLLGVLITIGEAVAYVLSGMYGDVRDLGAGNAILIIIQLFFAGIIVICLDELLQKGYGLGSGISLFIATNICENIIWKAFSPTTINSGRGVEFEGAVISLFHLLFTRADKVRALKEAFYRQNLPNVTNLLATVVIFLIVIYFQGFRVVLPVRSKSARGQQGSYPIKLFYTSNMPIILQSALVSNLYFISQLLFKRYSNNFVVNLLGKWKESEYSQSGQLIPVGGLVYYITPPTSLGDIVANPFHAVFYLTFMLTACALFSKTWIEVSGSSARDVAKQLKEQQMFMPGHRESNLQRELNRYIPTAAAFGGMCIGALTVVADFMGAIGSGTGILLAVTIIYQYFETFDKERASELGFFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5Y1</accession>
    <name>A0A8T0G5Y1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G016100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5Y1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035853511" evidence="1">
        <location>
            <begin position="24"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="14834" checksum="165D4E23AE2A8C56" modified="2022-10-12" version="1">MGRFKLLFFSTILLFAIQDGVSAIRHAPFFEDSKTQWFTSPWFIPNSVPKIVPVGAPIVEGIVPIGSPIAEVSTPISAPITEVLAPIESPIAEVATPIGSTITQIFTPIGAPFAQVATPIGSPIAQIFSPVAAPVVFTNVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5Z9</accession>
    <name>A0A8T0G5Z9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G017600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1900">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16254" checksum="E9E83C334F55A5E9" modified="2022-10-12" version="1">MKTKDTSVVVVGGGGKPVEEAGVDDDEEQLGVVEIVCDAIDHEVKSRSAAVMAIGDGYMASATTQLQLLMSKFPEHIRKMPMKKFVKQHCPNTKVRARSEGTLFFDIVQDPVFQPLGGGILDVSSGSASVQNMPSFEASQTSMAHHVLPCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7H1</accession>
    <name>A0A8T0G7H1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G119700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7H1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035747639" description="Secreted protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="111" mass="12968" checksum="E1CB5BEECC1A193A" modified="2022-10-12" version="1">MWLHYTKLLLLLLFFVEAFSSDVRVLALVIVDRPPLEAYHACLLIGHEPQILSLTKVQDHHHYEFFFPYLYRRSLADLLAWIYAMLLLSLMCSLFFSRCQGFGSGVWRGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8G8</accession>
    <name>A0A8T0G8G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G144500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF1">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1334" mass="152255" checksum="5C54415341C7DE5B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB56</accession>
    <name>A0A8T0GB56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G096900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6121" checksum="2995C56E305F45E5" modified="2022-10-12" version="1">MFVDSQSVQFGRESSSHGAFVRTASSNSMCRLCTVIQKERPDYKIFKPLCRSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCK1</accession>
    <name>A0A8T0GCK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G135000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="224"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27289" checksum="FC470706253BAE7B" modified="2022-10-12" version="1">MERHVGHIATGDDDVTDAWGTAQVVKHLALPVDRLELEAQLIDRRRGVADQVHPGAVTAVLRAGGQQLREYLGGVAVGEALDGPHLVLVQRVASGVGVAGCGADQPVGGDWEHVAANRIGQHGRGRRHLVRHHRVEHLRRQQQRHRRPARLIGLDVDVERLVQQIAVNPPQLPQVLHTVAPLPLRATPLVDSHIREAGQPTPVRLHQFVGGVLVGLLQHVAVTPRSSPPQSTTSLARYGRNFGEQRRSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG13</accession>
    <name>A0A8T0GG13_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G114100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035854178" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5589" checksum="6A7A78798EE7D9D8" modified="2022-10-12" version="1">MCTSLALTLLLIKDTPTPTLGRCCKVLVAQMESVSGPCSTHCTGHEECKGLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGS3</accession>
    <name>A0A8T0GGS3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G013000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34112">
        <property type="entry name" value="C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34112:SF13">
        <property type="entry name" value="OS04G0448200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="722"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="270"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="330"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="746"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="764" mass="81325" checksum="DBBFB29B70652368" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHN6</accession>
    <name>A0A8T0GHN6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_10G035800</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHN6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000108">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase S.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000178">
        <property type="entry name" value="serine/threonine-protein kinase PBS1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035920788" description="Protein kinase domain-containing protein" evidence="19">
        <location>
            <begin position="23"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="354"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="655"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="660"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0558540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="707" mass="78914" checksum="8A58B714540E0CB7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIJ5</accession>
    <name>A0A8T0GIJ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G025900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF119">
        <property type="entry name" value="OS04G0640500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="215"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="889" mass="98046" checksum="2C364222A4458800" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJG9</accession>
    <name>A0A8T0GJG9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G122600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="14052" checksum="15D194F55FAF6D43" modified="2022-10-12" version="1">MDWILGFKGPEVLKNLTSIGRGKYVQFYLRRRTHFQHVDLYKIQRPGVFWGLEPRIETNHFYRQSCFTEIAMLHDGIVTLTRCHNMQMPHEDYSHVLRLHNVYTEHRRESALGIRPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJP6</accession>
    <name>A0A8T0GJP6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G089000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJP6"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048868">
        <property type="term" value="P:pollen tube development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000007">
        <property type="entry name" value="probable xyloglucan glycosyltransferase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32044">
        <property type="entry name" value="GLUCOMANNAN 4-BETA-MANNOSYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32044:SF80">
        <property type="entry name" value="XYLOGLUCAN GLYCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13632">
        <property type="entry name" value="Glyco_trans_2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="11">
        <location>
            <begin position="310"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="688" mass="78019" checksum="E3ABB0EA34C302D3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJY6</accession>
    <name>A0A8T0GJY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-MurNAc-pentapeptide synthetase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G174800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.10">
        <property type="entry name" value="MurE/MurF, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051046">
        <property type="entry name" value="MurCDEF_CellWall_CoF430Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43024">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43024:SF1">
        <property type="entry name" value="UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="MurE/MurF N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="12">
        <location>
            <begin position="212"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Mur ligase C-terminal" evidence="11">
        <location>
            <begin position="465"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0558038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="601" mass="64784" checksum="3C0B3E6B279C8ADA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK68</accession>
    <name>A0A8T0GK68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G101700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>dTTP + alpha-D-glucose 1-phosphate + H(+) = dTDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="3"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000023">
        <property type="entry name" value="Glucose-1-phosphate thymidylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532:SF1">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="9">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0559403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="31748" checksum="20F714EC7B4A560A" modified="2022-10-12" version="1">MKGIVLAGGSGTRLHPATLSINKQLLPVYDKPMIYYPVSVLMLAGIREILIISGPEHLDNYKSLFGSGDQFGVQFSYAVQPRPEGLAQALVIGREFVGYDSVALILGDNLFFGEGLSELLASAVARPVGATIFAYHVENPHAYGVVTLDQTGRPLRLVEKPEEPESTWAVTGLYIYDNQVLDIAAVVTPSARGELEITSVNQAYLERGQLHVVRMSRGYAWLDTGTHDSLLEASEFVRMIQHRQGLQVACLEEIAFLQGFIDRAQLIARGELFAKTAYGQNLLRLARES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLN9</accession>
    <name>A0A8T0GLN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G138700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLN9"/>
    <dbReference type="OrthoDB" id="1893842at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.80:FF:000155">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005174">
        <property type="entry name" value="KIB1-4_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03478">
        <property type="entry name" value="Beta-prop_KIB1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="18"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="426" mass="48258" checksum="543B15872F2EF076" modified="2022-10-12" version="1">MGAAASTSEELQVVAMDEGVWQSLPEDLIERVLAWLPIHSLFKMRCVCKQWNSILFSERFVTRYTEVSPQKPWIIMYTAGRTSSAYNSTLKKWHDLVIPAVSPEKCVLAASEGLLCYGNEFFPWPNLFVCNPMTKFWQHLPPMRFIKTIHVVGMVSDRASKSFKILVAGLFFDEAHNGRLATEIFCSTANAWTIGGKPWPIMAAAWKLGAGYAVWSRGLFYCITFSPFGVIAYDLEKNLWDEVHVRMPASIVSPSLVECHGRLLMVGGCEEGTFLGIRIWELERSKMVWVEIERMPRKMRREFVELLRPSRHFFGFGNGNLICLTISESSPAIVFDLDDRSWQWLPGCPRLPDINNWQLRGISFEPRLDSNSHSSWGKDVLSANSLTLEDKPPNLLPHMTVGITTPTEPIDNPAHTISNGQSFQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR29</accession>
    <name>A0A8T0GR29_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G010000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9722" checksum="B87D751717A2D136" modified="2022-10-12" version="1">MVFLVDQINITFCAAADGTDDRVPRLLVISAQPCTVQLALATAYLPLLNPSKMCRFLYSSRITRSFKLVLRFIDLRVPTAAPGFKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS91</accession>
    <name>A0A8T0GS91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G046500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10139" checksum="D55D355D7B7266F1" modified="2022-10-12" version="1">MQAILGAWNTSTPNPESNLAGWNSAQKYPCEQEDGIGIPNWRGVQCITRIKCQLNVTTSIWECSSFIVALTLQSASITGSLPPEIGNISTLTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV44</accession>
    <name>A0A8T0GV44_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G040900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="36516" checksum="BB53BC2D4DB51439" modified="2022-10-12" version="1">MATSSGSFKGSISEAGSSMPGSMRSPLSSFMRSPISNSMMPSPVSSRLTMEFETAFLMEAEEPVRFSSTDILPYLSQPSSRSVSSSDFDSQSDESRSTSFCDFNDSNRITLGSLIGLPMDSFRHFGESFRFRMRGESQDFDSAGGSMRTADESPRRSRTCSLLGDLFRCLQRTKTDYLQPTVPDGRNPTNLTSLTSFTITEVSEEEERDSDSDVGPTVFDNSVFVERDTLGSRIYEFNPLYISDAMSDVDSTDSRSLSLSGDHRQATCGESNINVKKITNPTDSGAVEMPRLTVQVNSNASPICRSQPLSPMRAVLTTVCCQLGDDSDEYTSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVB0</accession>
    <name>A0A8T0GVB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G019000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006569">
        <property type="entry name" value="CID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000313">
        <property type="entry name" value="PWWP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12550">
        <property type="entry name" value="HEPATOMA-DERIVED GROWTH FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12550:SF70">
        <property type="entry name" value="JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04818">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00855">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00582">
        <property type="entry name" value="RPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51391">
        <property type="entry name" value="CID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50812">
        <property type="entry name" value="PWWP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PWWP" evidence="2">
        <location>
            <begin position="33"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="CID" evidence="3">
        <location>
            <begin position="923"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="267"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="426"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
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            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="648"/>
        </location>
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        <location>
            <begin position="686"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1158"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1178"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1255"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1281"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1366"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1512" mass="159037" checksum="341D87580F58CC34" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWL1</accession>
    <name>A0A8T0GWL1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G019400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38377">
        <property type="entry name" value="THREONINE-TRNA LIGASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38377:SF1">
        <property type="entry name" value="THREONINE-TRNA LIGASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11511" checksum="BA5066D562817369" modified="2022-10-12" version="1">MGGSKDIASLLQPFEERAQLAEERLAKLESAAQHPQGSSGQEDLLQSLTELRKKLVAAKAEQDAEKKKLIDENKKLQYQILHLKRAVQDADDKCAAAEAKLAKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZE9</accession>
    <name>A0A8T0GZE9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribokinase</fullName>
            <shortName evidence="7">RK</shortName>
            <ecNumber evidence="7">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G095200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>D-ribose + ATP = D-ribose 5-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="7"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033730">
        <property type="term" value="F:arogenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000029">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046826">
        <property type="entry name" value="PDH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="Ribokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045011">
        <property type="entry name" value="TYRAAT1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059064">
        <property type="entry name" value="TYRAAT2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43207:SF4">
        <property type="entry name" value="AROGENATE DEHYDROGENASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43207">
        <property type="entry name" value="AROGENATE DEHYDROGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26213">
        <property type="entry name" value="TYRAAT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="8">
        <location>
            <begin position="377"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="229"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0564243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="648" mass="70306" checksum="A584993D9C1E7AAD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Z2</accession>
    <name>A0A8T0H0Z2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G154700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0Z2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="274" mass="29347" checksum="29D23D3C81AD80AD" modified="2022-10-12" version="1">MGEMGVVSFEEALAVACFASFCSILGALVVMFISQPGSAYVSRPWLYAIIKSFLSGAVTMATFVNSDHTACKGTVGWATVITGSLTAGFASAAVGHDPPKDVALTEHEWNELVKREFESPRARQRDLQGGILTAVVIGLRNLAYGVWFFSSMSVWQRFMLEMSGTSLLRFLAPQFIVLGAAVAVPMYFGGGKWSALLAVAVSSAAFPLGYTVATLALPSNDVVCWSVEFAGYRAMGMIQALTLLYFFTSSLQNAPTRHCLIASTFGLACMVGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H200</accession>
    <name>A0A8T0H200_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G171000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H200"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15495" checksum="052CAB7CE14CC4F5" modified="2022-10-12" version="1">MTPRTNLQRRPQHRALSSQPYQSLNSLPVEILPVGKPLQTKSTLTTNNSQNHSSLSLSLPLSTHNLAVRLCYATRRELSATPRAIYWSHVSQIRANIQTPSICQSGTPSPPPRRSMLITQKQLHSVELAHEIGYYICE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H507</accession>
    <name>A0A8T0H507_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G055300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H507"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371:SF26">
        <property type="entry name" value="DUF4005 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371">
        <property type="entry name" value="OS01G0551000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="543"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="719"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="561"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="719"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="738"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="885" mass="97291" checksum="ECFE2F4DA2BBEE09" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H603</accession>
    <name>A0A8T0H603_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G085400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H603"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="18642" checksum="0E542A70F1E900C0" modified="2022-10-12" version="1">MGQDIPAGYSDKPRIGLNGGMNPENLRRRDPKSRELLGPLFGQVAVATVRNVLYNGVGKLQNVDKMLANKIAQLRERKDQLPVTKNEDEHLDQRDESGGDCSLEPEGMIATLITLHTSSNYSTCSNSSEPKPCELFHRAKGITNQVPFGCNIAGYLVNQISEESTVHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6F6</accession>
    <name>A0A8T0H6F6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G053100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6F6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35508">
        <property type="entry name" value="VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35508:SF1">
        <property type="entry name" value="VOLTAGE-DEPENDENT L-TYPE CALCIUM CHANNEL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="246" mass="26846" checksum="02866DD3ECE64809" modified="2022-10-12" version="1">MAESTSAQQVQSEGPCKKMEDLDDAVGEAVHVFVEERKGKPISVVARLRTLVHHPKMSLKIEHFTFSDAAKWVRQGRPAWRGFLIAAVLIAAFAALTGLVAFALIFISSSLNVAFASFLVAVSTIGFIWAFFFSSITVVYMGALGFGGLTIGSIAFFSVWAVIILSGWAGIAWVIWQGLRKAFQIGRYLILLAGSFLLSFPAVQELGAKFKEYVAQVQACTGSLKLHLGAKFKEHILLKQKKTAMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6G1</accession>
    <name>A0A8T0H6G1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G091000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00488">
        <property type="entry name" value="PCD_DCoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="entry name" value="Transcriptional coactivator/pterin dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599:SF0">
        <property type="entry name" value="PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="PCD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="168"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0566830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="360" mass="40169" checksum="49F85FC1CB2F6A28" modified="2022-10-12" version="1">MKKKVMRDINRPPDTVKTSRKGTSGRSELPRVGQAAQGLAPLQEQEFDALKHGQSKLFSDDDLQERLKFLSNWKLSPDRRSISRTFQARNFAEGINIFNAVAKLAEEYDHFPDLHIMDNRKVTVVLTANQIQGLSSSDINMAERFNNIDIPYAETLKDFEHSPRLFEVERSEDSSQMQPMSGSVQPLGIFSQQHSPEAADNPQSRKSDKISFPERQHVTSLMERTGEDEVEAQEVNEKSAPALLHSLILIFAEAGPGGLAVQEAVRRIRKQGLPGLREKGKAAQVANVTRNHPDFVACDDVECFALRKSLLRSFQCGSLDPEEYADEKKMEATVLETYAASAAALELKLSSPKSTDVSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6H1</accession>
    <name>A0A8T0H6H1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UBE2O-like tandem tSH3-B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G091800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6H1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057735">
        <property type="entry name" value="UBE2O-like_tSH3-B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23046">
        <property type="entry name" value="tSH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBE2O-like tandem tSH3-B" evidence="4">
        <location>
            <begin position="146"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0566840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="48745" checksum="E4535DA5DA2CE9E8" modified="2022-10-12" version="1" fragment="single">MEMLVGHVSCQKPHPTQLIREDLVQKISNPEQIGIVSKLPGDSISTSNLGLINEDVDGEQNCIPPGQARIVWLKSQETNEDMKDLQVLDRSFMLGDVVAPCANPVGQTGIVMEISMAVDLELPSSGNVVQGIDSRRLRRVRTYMPGDFVVHGNWLGRIEEVMDNVTVVFEGGAKCKIFRADTERLIPVQSGLIDDNNSPYYPGQRVRGASPGVFKLAKWLRGTWKATRTEGIVGNVEVGSVLVYWITSAITSSSGIQSSSAPAMLQKPCALFPLMYISHTNWQLGDWPLLPHGFDAIDQTLSISDEGNKSEQQSLDHKLAGHSSPIDCEKDQESSTSSLDKEVIVGTLITHKVKQSKQQKKALKKERRIAMKRERGGEHAALVLKTKTKVDVLWQDGTKSCGLEASSLIPVECLGDHEFWPEQYVLERGLDGEGNDHVECRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H708</accession>
    <name>A0A8T0H708_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-fructofuranosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G104500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H708"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18624">
        <property type="entry name" value="GH32_Fruct1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.115.10.20:FF:000001">
        <property type="entry name" value="Beta-fructofuranosidase, insoluble isoenzyme CWINV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050551">
        <property type="entry name" value="Fructan_Metab_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31953">
        <property type="entry name" value="BETA-FRUCTOFURANOSIDASE, INSOLUBLE ISOENZYME CWINV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="117"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="438"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0567020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="642" mass="72347" checksum="59CC37B27EA715FB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9V0</accession>
    <name>A0A8T0H9V0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G148400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10129" checksum="D4F95B0E8191DD20" modified="2022-10-12" version="1">MKKMNLPISVEDVKREVEILRTLSGHENVLQIYAAFEDDDQVCIVMELVFVAADSATYCSLYGLCFDEYLLLGFWQRVILGLTLSSSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAA5</accession>
    <name>A0A8T0HAA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">phytol kinase</fullName>
            <ecNumber evidence="12">2.7.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_7G034700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>phytol + CTP = phytyl phosphate + CDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:38055"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17327"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:75483"/>
            <dbReference type="EC" id="2.7.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cofactor biosynthesis; tocopherol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.182" evidence="12"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAA5"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010276">
        <property type="term" value="F:phytol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010189">
        <property type="term" value="P:vitamin E biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523:SF8">
        <property type="entry name" value="DOLICHOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PHYTOL KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="213"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00039024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0566052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="357" mass="38663" checksum="E8BEA48DCD8800E1" modified="2022-10-12" version="1">MGTANLGAAALGSGAQSLLLTKHREVSRSCSTLGRNWVRSHRPGATSQQVNFPSRNHVHATSQQSLLVDFPSPRHVHASVGGAHEAGEQHQAHVGIDGGDGGVWTVPPVQHDVGVTLIVLVGGWVWVRIFDFLTKRKYLGQKLSRKMVHITSGLLFAACWPFYSSFPWAQYLAALVPVSNGIRLLVYGLGLLKDEGLVKSVSREGDPRELLRGPLYYVVVLVFSTVLFWRDSPVGVMALAMMCGGDGIADIVGRRFGSSKLPYNSGKSWAGSIAMFLFGFLVSYGCLWYFSLMGFYELDTKGTLLRLAVVSLAATVVESLPISTKLDDNVTVPLTTVIVGMLLFPSDANVFGLPNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAM6</accession>
    <name>A0A8T0HAM6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G050800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035778608" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="5996" checksum="417906A936AB48D6" modified="2022-10-12" version="1">MEKLELSITHLVFLLLQAESLLMCLGLWNEDSSMDNPNGPGCAVSIEATSFLIPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBG5</accession>
    <name>A0A8T0HBG5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carbohydrate kinase PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G065600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBG5"/>
    <dbReference type="OrthoDB" id="415590at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000025">
        <property type="entry name" value="Putative sugar kinase slr0537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052700">
        <property type="entry name" value="Carb_kinase_PfkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43320:SF3">
        <property type="entry name" value="CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43320">
        <property type="entry name" value="SUGAR KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="5">
        <location>
            <begin position="187"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="504" mass="53361" checksum="38E0CEF729733D3C" modified="2022-10-12" version="1">MAAIANLPSLPLRTGGLLSAAISEENSCARQLRGGAWAGSNLVASSSSSVSIASSSSLSLVARFGGEVRGRGSFFRGDQTVLFMIHRLVCACNGGGQRQGTVCYASDRDVENAGYQMNGDPQRIEEQPYGIPDKKVPERWDVVGLGQAMVDISASVGDDFVERLGLVKGTRKVVNHEESWKVLRDIDGRDYKVSAGGSLSNTLVALARLGMASSKNSAQNVAMTGSVGSDHLGDFYRTKLLRANVHFLSQPVVEGTTGTVIVLTTPDAQRTMLSYQGMSSIVNFDTVLASAIAKSRVLVVEGYLWEISQTIDAIAQACEAACQQGVLVALTASDVSCVTRHRQQFLDVMCKSTDILFANADEARALCGFGENSTPEQAAKHLNQFCPLVSVTDGARGSYIGLRGELVFIPPAPCVPVDTCGAGDAYAAGVLYGLLRGIPDVKGMGDLAARVAAIVVGQQGTRLKEEAAVELAESVNSLSDLLDTRLMELMGMKDQVQPKKISSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBX3</accession>
    <name>A0A8T0HBX3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G018000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="21317" checksum="E7AEF3DC4C97D504" modified="2022-10-12" version="1">MGNRTELIRRERLGTLKIHGIYIIFFSLVSLLLQLCTLLHSCCSTILLTHLKHLSRRTVGRMITGGVNGLKSLGRWTPCRTLLERRFAQERSPSIDDEKPKKSTATGATSGCQQAQPLKTTARQETKADSDTGEIPTPSLLKATSTKDFILSEREKRLRQKSKEKDEEVDVMKLEETFRKGKSTADLDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBY1</accession>
    <name>A0A8T0HBY1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G084100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1740.10">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="AlgH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31984:SF17">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31984">
        <property type="entry name" value="TRANSPORTER, PUTATIVE (DUF179)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143456">
        <property type="entry name" value="VC0467-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="13013" checksum="7C1FB42F8EFEA54D" modified="2022-10-12" version="1">MKAAHMIIKNMFRRWYCCWFRRIYFRPNWLLGFRMVCLVVRMHLLTDFVGAGWGPGQLEQEVEATVWYLTSCSKRFVLNQCIQLPKPLWNEVMEHMGPPYSDILRRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCE0</accession>
    <name>A0A8T0HCE0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G031100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCE0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000005">
        <property type="entry name" value="Glucan endo-1,3-beta-glucosidase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044965">
        <property type="entry name" value="Glyco_hydro_17_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32227">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00587">
        <property type="entry name" value="GLYCOSYL_HYDROL_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0568585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="479" mass="50955" checksum="C5A09193F3EDB223" modified="2022-10-12" version="1">MMTMDEDSGVLVRQMEDGHASRRWRNAGEWRHRSGSRNLTFILLVMLVSGLASPALCNYAPEDYTMGINYGRVGDNLPAPTEAVKLVSGLGIGRVRLFDPDAATLFALGGSGLQVVIGMGNDAIPPLTDAATADQWILTHIVPYVPSTNITTILVGNELFTDTTRSAIWLQLVPAMQNLRTSLLNRGLSSIKLSTAAELNTLGWSYPPSKGVFRTDIAVPVLTPLLQFLNDTDSYFFINVYPYFGWRDDQSYVPMDYALFTRKTPFIVDGNHSYYNLLDAQLDAIAAAMERVGFSSVRLAISETGWPTVGAAGNVGSDTTTNAKTYNSNLISYILGRKGTPRRPGVFIPTFVFALFNENLKPGGVAEQNWGVLYPNGTDVYPLQWSNGTSASPVIAPTTSPSPVVAPTLPPLASAPVPSAAPAVAPLVGSSATPSVSAAPVAPSVGPSAGPLENAASRGATLGGLSVLLAIFVANFLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCR9</accession>
    <name>A0A8T0HCR9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G080800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCR9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="18623" checksum="571BBE6C152A80DB" modified="2022-10-12" version="1">MQIIHYIYLHIIATKCLMTDKPIIQLERTKLSVAACMLVQNGQDRRRSFISPEGLRSAYNLTFLLKCSNKCIIHFCAGVDDKRLSLDMRSVAQSMFATEKRHSFSPSRGKISYADETHTWYLTDKETHPLARFQGPTDLVKEFTHSAASTGTPHLHVPKSPTQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFN6</accession>
    <name>A0A8T0HFN6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G090600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFN6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF184">
        <property type="entry name" value="EXOSTOSIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="6">
        <location>
            <begin position="88"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0569437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="495" mass="55823" checksum="1A3F5B66DCDA763C" modified="2022-10-12" version="1">MSRKVLRLWSLSFVLVMFWFKWRAMDYRILSSNGTATTPEYSFLVSLHAFSMKHSETPFINSGVSPASKADDGERFNWFVMSDTAAPARLNVYVYEMPAKFTTDLLWLFQNSQEQTVNLTSNGSPVHRLIQQHSVDFWLYSDLMALEDKRLVRSVRRVSNQAQADVFYIPFFTTIPFFLLSRSQSKLLYKEAVNWITAQPAWQRSGGRDHVLPVHHPWSMKSHRRFLKAAIWLLPDLDSSGNWYKEGEVSLEKDVVMPYVANVRACDAPCLAISSSLRKTLLFFRGRIVRNSGGRIRAKLAAVLRDEKGVVIQEGSSGVEGNAATELGMRRSVFCLSPAGDTPSSARLFDAIVSGCIPVVVSDELELPFEGILDYRQAALFVSAAQAVQKGWLVAHLRNKTSHEIATMQQQLAQVYLSTIQNVACNVQLLQYARHFQYATPAQPLGPEDLTWRMVAGKLQSVRLHISRSQRLVQGALDTCSCYCTRANLSVPSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG58</accession>
    <name>A0A8T0HG58_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal lipase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G184700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="114"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="755"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="946" mass="104882" checksum="38DD2A80B45576EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGS6</accession>
    <name>A0A8T0HGS6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_6G097700</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0430">Lectin</keyword>
    <keyword evidence="14 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="314"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="370"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0569534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="776" mass="88009" checksum="F6622F20745900BA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHG5</accession>
    <name>A0A8T0HHG5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G108100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5791" checksum="F1885987061B5EC1" modified="2022-10-12" version="1">MLHLQLFIATCTRRLTDPIPTWITPPKFLEIAGVHITTLGTNFGRVHCQGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIZ7</accession>
    <name>A0A8T0HIZ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Cellulose synthase</fullName>
            <ecNumber evidence="22">2.4.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">KC19_6G164100</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 22">
            <text>[(1-&gt;4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;4)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19929"/>
            <dbReference type="Rhea" id="RHEA-COMP:10033"/>
            <dbReference type="Rhea" id="RHEA-COMP:10034"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18246"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="22">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="22">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 22">Glycan metabolism; plant cellulose biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 22">Cell membrane</location>
            <topology evidence="2 22">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 22">Belongs to the glycosyltransferase 2 family. Plant cellulose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.12" evidence="22"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIZ7"/>
    <dbReference type="OrthoDB" id="72851at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016760">
        <property type="term" value="F:cellulose synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030244">
        <property type="term" value="P:cellulose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16617">
        <property type="entry name" value="mRING-HC-C4C4_CesA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000031">
        <property type="entry name" value="Cellulose synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000009">
        <property type="entry name" value="Cellulose synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005150">
        <property type="entry name" value="Cellulose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027934">
        <property type="entry name" value="CES_Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13301">
        <property type="entry name" value="X-BOX TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03552">
        <property type="entry name" value="Cellulose_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14569">
        <property type="entry name" value="zf-UDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 22" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16 22" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="12 22" id="KW-0135">Cellulose biosynthesis</keyword>
    <keyword evidence="6 22" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 22" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 22" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 22" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 22" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 22" id="KW-0862">Zinc</keyword>
    <keyword evidence="10 21 22" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="865"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="899"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="933"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="976"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="1017"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="22">
        <location>
            <begin position="1047"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="24">
        <location>
            <begin position="38"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="78"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="237"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="401"/>
        </location>
    </feature>
    <feature type="active site" evidence="18">
        <location>
            <position position="787"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="567"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR605150-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR605150-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR605150-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU361116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0570462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1086" mass="122411" checksum="130F7BA0B4F1EFDA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJH7</accession>
    <name>A0A8T0HJH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G199900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="20586" checksum="46357B7BE00B5640" modified="2022-10-12" version="1">MQPMTLKAFSGVNLSCLPLKKSFGCSHEACDGFSEVESASSYNSNALKYQVRGANAVRGADNRAKILREQATKKAKSEPVRLLPPGPAKQTSHQGKGNISVMVLSLLRRKQPDVKSTSRKSSTVPKTKPAIVGGLLCPLNGKNIKPPSKSDVVSVKVSSFDLNGKSIKALSIRDVLERQEKQDQRHLNGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJI2</accession>
    <name>A0A8T0HJI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G200000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="459" mass="51382" checksum="48C6F2AD187A8E84" modified="2022-10-12" version="1">MDCALEESDARALRDLGAFVNCSEHSSVPCFYSCEFATPAFETSRERPSFTVSLARRGSLAIESECQNLDKSPIFHIGAANIKGAVNLLKAIRILVSCRTLTDAQFSILDYGACWRPDGIPPRSQDFMSEDLMSEVFTLFRSSPSLSCFHFINSLSDASLYCKHLQTLVCENPRLETLTVLAGGLNLVVFAEAIAVCLSRNTVLNSFMLRDPTNFAQLNRESLEILLRPLTSTSPSEANAKLNELALHLQYPDGHSVDAIANLVCRNTALKKLDLRFSNFRSGLEDGNSLWREFCRALEVNQTLEELRCPCEVAALRELLVPFVPDRYGRQPNSTISTLRLSIAIVNDPEVVLRDLASALQSNTSLKHVQCIYECDGNGTYMDDVKYITDKNLCQAEIQIQEILRTMIDNELRVNTSLESLVVGHWTLLRVGTEWQTSYRGPCLREQTGDYNVKVKLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJM7</accession>
    <name>A0A8T0HJM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G203700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035920225" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8859" checksum="DC30D39012B33236" modified="2022-10-12" version="1">MNILKAEWLICFICDTSLAFDAFAGSGLKAGSNMNVKGRVTTTKTHDVLSTPSNPDQLSMITLLNHLEQQCYYWYYYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJW1</accession>
    <name>A0A8T0HJW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exocyst component Exo84 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G210400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO84 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJW1"/>
    <dbReference type="OrthoDB" id="642193at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="6">
        <location>
            <begin position="160"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="758" mass="83051" checksum="0F4B39565B5EB32B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLC2</accession>
    <name>A0A8T0HLC2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG026600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035892375" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9356" checksum="B92BD429B5038721" modified="2022-10-12" version="1">MSMFGVCTHLFYVLILVLLPSLGTLPEAFSVSKALSIHQFDPCFVHVVGEYRVDVKRKTSVPDHIPYSAKYLIAHHRSVNCPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNB2</accession>
    <name>A0A8T0HNB2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG082600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035781143" evidence="2">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="13251" checksum="97EE21B1B873B3AA" modified="2022-10-12" version="1">MNHITMFMWLMQTRSLTSWRILLSTLIRNFNRPCRSNNKDQSFSSFLALPELIPAAKRRRQQPLVDFTKSRILTSEESVSVCEQLLKKRQENEEATKRRAAERKQIKKQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HND8</accession>
    <name>A0A8T0HND8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG094600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HND8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13792" checksum="49714AC34979CD1F" modified="2022-10-12" version="1">MGRVLLPAKRRRRSPRLQSRVHPVPTKATRDSSSLSTPARSVVAMDDVHLERMNICRPCTAIPVSVELILFCLKFRILEFKIQFNRRGYSGNRPYRAKGTLPFCHAVLGLQLLVVVLAVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNG6</accession>
    <name>A0A8T0HNG6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG097200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035895112" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6513" checksum="7CDB12F12CE6C824" modified="2022-10-12" version="1">MTWNNVIFHVLFYMISTSDYLWPSWKTLTSTLIITGRSETAGVSWRFQLNTNVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPF3</accession>
    <name>A0A8T0HPF3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG116300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035736083" description="Secreted protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7175" checksum="B0B2D282D198182B" modified="2022-10-12" version="1">MIVACFSCRLDMGLGFCVWLSFGTSLSSVRGCEVGAARGCVHATAFRSLGHRIDARFAAWHGHQFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQU2</accession>
    <name>A0A8T0HQU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG149300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035722927" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="139" mass="16757" checksum="F1FF399A1ACD584B" modified="2022-10-12" version="1" fragment="single">LLHLPLLTLISALITSHRWTQQIKKVNKYFQTIWTRNLRIHISRATTHIRNTNPFMKVKKNQKRYNRTTSKKKHTRRNRRNTSMFIILLPRHILMPSQHHQTSQEGEHAHQRASNQKTKHPCKLLPHLEFCNLGWNCFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTJ7</accession>
    <name>A0A8T0HTJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG210900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12641" checksum="DE5720EB126B49A2" modified="2022-10-12" version="1" fragment="single">ALANSHSFCAPPWHPGPILPPNVFPETLTKTPKQPRNPNLNDPTCAINHKRHNTTIAANTPERYRTLEARRTRHEAFRGDAHVRDSNAARVRRQNWPLAMHQSGWEKPVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX67</accession>
    <name>A0A8T0HX67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G005800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX67"/>
    <dbReference type="OrthoDB" id="272977at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006904">
        <property type="term" value="P:vesicle docking involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007191">
        <property type="entry name" value="Sec8_exocyst_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048630">
        <property type="entry name" value="Sec8_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20652">
        <property type="entry name" value="Sec8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04048">
        <property type="entry name" value="Sec8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component Sec8 N-terminal" evidence="6">
        <location>
            <begin position="15"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex component Sec8 middle helical bundle" evidence="7">
        <location>
            <begin position="338"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="537"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="854"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="855"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="869"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0575466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1088" mass="119744" checksum="C9DF57585D9BE327" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYZ9</accession>
    <name>A0A8T0HYZ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G056000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
            <location evidence="4">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the nucleoporin interacting component (NIC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016973">
        <property type="term" value="P:poly(A)+ mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007231">
        <property type="entry name" value="Nucleoporin_int_Nup93/Nic96"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225:SF4">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11225">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04097">
        <property type="entry name" value="Nic96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="152"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="152"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0576106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="863" mass="95154" checksum="1914CAB20A5B9143" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1G3</accession>
    <name>A0A8T0I1G3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_5G113500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1G3"/>
    <dbReference type="OrthoDB" id="10301648at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="48"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0576857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="472" mass="53404" checksum="F5B964D1570FF9B6" modified="2022-10-12" version="1">MKMGSEGRLSESYGEIEELHERLKCARTNIPDPTVKGRLNILLFQGPSIYDAWFSATSNQVAQVLLTLPTSFAQLGYASGVALQLFYGIVGCWACYMISWLYIEYRTRMEREGHSFKTHVIQWFEVLDGLLGKKWKYVGLAFNCVYLLFAAITQLIACGSNIYLVNDGLNKREWTYIFGACCLVTIWIPSFRNYRLWSVFGLITITYTSWYMTVSALVYGQAPGATHDGPNSLVLYFTGATNILYTFGSHAATVEIMHAMYRPVKFKYVYLFATLYIFTLTIPSSMAIYWSFGDALLENSNALSLLPKSTARDVAVLLMIIHQFVTVGFAVTPLYFVWEKILGVHQENNMLLRASCRVPIILLIWFLAIAFPFFGSINSVLGCLLVTFSVYIIPCLAHMVYFCNSSIRAPSVEKPPFFLPSWTGVYVVNTFVIWWMVAVGIGFGGWASITTFIKQIWDFGVFNACYQCLQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2Q6</accession>
    <name>A0A8T0I2Q6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Inosine triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">ITPase</shortName>
            <shortName evidence="13">Inosine triphosphatase</shortName>
            <ecNumber evidence="13">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="13">NTPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">XTP/dITP diphosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G119200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="function">
        <text evidence="9">Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ITP + H2O = IMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29400"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-hydroxy-dATP + H2O = N(6)-hydroxy-dAMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:83971"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:233529"/>
            <dbReference type="ChEBI" id="CHEBI:233530"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:83972"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XTP + H2O = XMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:28343"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="13"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2Q6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009204">
        <property type="term" value="P:deoxyribonucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.950.10:FF:000003">
        <property type="entry name" value="Inosine triphosphate pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03148">
        <property type="entry name" value="HAM1_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027502">
        <property type="entry name" value="ITPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="RdgB/HAM1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00042">
        <property type="entry name" value="RdgB/HAM1 family non-canonical purine NTP pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067:SF9">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="18"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="178"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ITP</name>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00093218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00093255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00093271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0576933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="210" mass="22995" checksum="12F481C11D56B0E8" modified="2022-10-12" version="1">MAAMKVQMTLTKPVTFVTGNAKKLEEVKMILGQAIPFQSVKLDLPELQGEPEDISREKARLAAKEIGGPVLVEDTCLCFHALNGLPGPYVKWFLAKTGHEGLNNLLAAYDDKSAYALCVFSLALGPDSEPITFSGRTEGKIVPARGSGNFGWDPIFQPVGSDLTFAEMLKEEKNKISHRRRALDKVKEYFYDFNYAPRLGGVPDASADTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5S3</accession>
    <name>A0A8T0I5S3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Metal-nicotianamine transporter YSL7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G025400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YSL (TC 2.A.67.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5S3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035673">
        <property type="term" value="F:oligopeptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004813">
        <property type="entry name" value="OPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045035">
        <property type="entry name" value="YSL-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00728">
        <property type="entry name" value="OPT_sfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31645:SF0">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER YGL114W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03169">
        <property type="entry name" value="OPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="420"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="593"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="634"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0578467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="715" mass="78381" checksum="965BCFD70292B302" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5V0</accession>
    <name>A0A8T0I5V0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G025300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="181" mass="19722" checksum="E17C1CBB2CFB2F94" modified="2022-10-12" version="1">MGLHYLKAENTWIKQRIDQATCLLGLLHGSLHTQQHEPNGNASERERAHDGHNLENLRRDVAVGSQCTPTRRLPAPASAHASERLLGALRHPHARHPTLRLQPSEALDPPHPQLGLGLGRCRCQRRRHHGGHGHGGGDGGGCHCKFEGDGDGCDRAETRRDESGDCNLLQGGALAVEMKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5X1</accession>
    <name>A0A8T0I5X1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G029100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5X1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15276" checksum="C38794260BA44509" modified="2022-10-12" version="1">MTSTSSGQSNIPTQSTSSGQMPVNSNYPQRPPYLHPWASQMMYSGAVPPSIDSSSQLQYLYQGCQHPSLQNNSVPVPHVRNSMSQFAPTGAMENYRRLSLSHSRAIQQNSSQSHSLSSPISSQLPRSRGGDGECEQRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I774</accession>
    <name>A0A8T0I774_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G052100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I774"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="8896" checksum="D047C06D83C2360F" modified="2022-10-12" version="1">MSQLSSECATWSANRCKFRHGLNWEGSASECGAGEVDLRIRHGLVIAGGGPSGRRCFLFAEDSCLSGSLIKSTYGWGAPDLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7T8</accession>
    <name>A0A8T0I7T8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G066400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7T8"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001864">
        <property type="entry name" value="Calcium-dependent protein kinase SK5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000085">
        <property type="entry name" value="CDPK-related kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000101">
        <property type="entry name" value="CDPK-related kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001294">
        <property type="entry name" value="CDPK-related kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="157"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="460"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0579019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="68457" checksum="4D192A00ADC8362F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8G3</accession>
    <name>A0A8T0I8G3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Lipoxygenase</fullName>
            <ecNumber evidence="14">1.13.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_4G139900</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Lipid metabolism; oxylipin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the lipoxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="14"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8G3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031408">
        <property type="term" value="P:oxylipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.245.10:FF:000002">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.375.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.372.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020834">
        <property type="entry name" value="LipOase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020833">
        <property type="entry name" value="LipOase_Fe_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001246">
        <property type="entry name" value="LipOase_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027433">
        <property type="entry name" value="Lipoxygenase_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00087">
        <property type="entry name" value="LIPOXYGENASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00468">
        <property type="entry name" value="PLTLPOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00308">
        <property type="entry name" value="LH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00711">
        <property type="entry name" value="LIPOXYGENASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00081">
        <property type="entry name" value="LIPOXYGENASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="11 14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9 13" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 14" id="KW-0925">Oxylipin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLAT" evidence="15">
        <location>
            <begin position="113"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoxygenase" evidence="16">
        <location>
            <begin position="240"/>
            <end position="952"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0579980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="952" mass="105244" checksum="A2306AFE2A6B9EC8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8S3</accession>
    <name>A0A8T0I8S3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">nepenthesin</fullName>
            <ecNumber evidence="9">3.4.23.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G141300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Extracellular proteinase found in the pitcher fluid of carnivorous plants. Digest prey for nitrogen uptake.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Similar to pepsin, but also cleaves on either side of Asp and at Lys-|-Arg.</text>
            <dbReference type="EC" id="3.4.23.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.12" evidence="9"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8S3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000033">
        <property type="entry name" value="Aspartyl protease family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000016">
        <property type="entry name" value="Probable aspartic protease At2g35615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051708">
        <property type="entry name" value="Plant_Aspart_Prot_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47967">
        <property type="entry name" value="OS07G0603500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47967:SF60">
        <property type="entry name" value="PROTEIN ASPARTIC PROTEASE IN GUARD CELL 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 11" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="159"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00053221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0580004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="508" mass="54700" checksum="994BD178258E7C43" modified="2022-10-12" version="1">MALMTRSAAALHYQPAAETAAAAACLSIFLFAILLPSTNAHTIAEQYHVPLEGESFQLHTLHTTPIHTSTGSTTDPEELGFRMKITHTDAPSSPFSKQQASRAELHSRLVERDLARVDAIGKHIRTRSRHHASKATDPSAGPSLKDPVKSGLTSGTGEYFVTLQIGSPPKDVIATIDTGSDVFWLQCKPCQQCYQQIGPVFDPAASSSFTTLKCASPVCTQLQFFKCGKNSKNCLYAVAYGDGSVTVGDFAQDTLTLTSISGRPYKIPQFSFGCGHVNQGLFVGSGGILGLGRGKLSFPTQLSGKVSNRFSYCLTDRFVNPDANSHIFFGGTMSNGLQYTPLTQNPHLPAFYYVGLTGITVGKNVITFPASLYQLDSVGNGGVILDSGTSITRLMEPSYSIFRDSFRAATRYLERVEGDSLFDTCYSIKGSATNIPPVNLLFQNKASLVLPANNVLLPIDSQGTYCLAFAPSYVNISIIGNVQQQNFRIEYDLANSRVGFGTADCATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8Z0</accession>
    <name>A0A8T0I8Z0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="26" type="ORF">KC19_4G059700</name>
    </gene>
    <organism evidence="26 27">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="26" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="26">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="26">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8Z0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010074">
        <property type="term" value="P:maintenance of meristem identity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010082">
        <property type="term" value="P:regulation of root meristem growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000453">
        <property type="entry name" value="Leucine-rich receptor-like protein kinase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000385">
        <property type="entry name" value="Leucine-rich repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000417">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000430">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase PEPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000260">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase RPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000775">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000:SF679">
        <property type="entry name" value="OS01G0170300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="19" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="16 23" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-0675">Receptor</keyword>
    <keyword evidence="27" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10 24" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 23" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 23" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="24">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035929144" description="non-specific serine/threonine protein kinase" evidence="24">
        <location>
            <begin position="26"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="23">
        <location>
            <begin position="823"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="25">
        <location>
            <begin position="892"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="921"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAG0578913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1191" mass="129495" checksum="91951B685929656A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I944</accession>
    <name>A0A8T0I944_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G063900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I944"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035945729" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9309" checksum="71CDF697E7F4ADE7" modified="2022-10-12" version="1">MWRRTTTCLMLPGLSTLAWSLPSTSRSNIGSLRSRMISPDHKPSLDNCILLVCSWKATFMYSELEAEINGLKNGNDIGTRIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB99</accession>
    <name>A0A8T0IB99_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G215600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035891792" evidence="2">
        <location>
            <begin position="18"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="7090" checksum="1AD5DE6997AAB5BD" modified="2022-10-12" version="1">MVATILLTLSLSSSTHPKQKPTTHLSKIPSKTQSRDINCISSKLLINCTTNNTHSIALIPSLTSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDR7</accession>
    <name>A0A8T0IDR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquinol-cytochrome c chaperone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G217000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021150">
        <property type="entry name" value="Ubiq_cyt_c_chap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007129">
        <property type="entry name" value="Ubiqinol_cyt_c_chaperone_CPB3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12184:SF1">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03981">
        <property type="entry name" value="Ubiq_cyt_C_chap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome c chaperone" evidence="2">
        <location>
            <begin position="116"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="29811" checksum="52D80644A182FA7B" modified="2022-10-12" version="1">MLAQVARAGVRRHLARASATQLLSRSFAQAAEQVVDTASSDKDFETENRRTVDARSLSLDSSSRLRVVDPAPEGFKRTVLTLLGYYGKQSRLIRGANTLYSRISSQVDQPELYANFVLEQNFRTTHAMLVLHMWLSLSRLRSEGRDGGVMGQSLYDAFNHDLERRIIATGLKVLLSKWMKELEKNFYGAVASYDKAMSPEAAQDELARALWRNVFAEDDSIMPTGPNATPVHALARHVRKEAACLALTDSESFLTGNILFSQNIGATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG34</accession>
    <name>A0A8T0IG34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_3G014700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 21">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HRD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="5"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG34"/>
    <dbReference type="OrthoDB" id="7759664at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16479">
        <property type="entry name" value="RING-H2_synoviolin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000194">
        <property type="entry name" value="ERAD-associated E3 ubiquitin-protein ligase HRD1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057992">
        <property type="entry name" value="TPR_SYVN1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058051">
        <property type="entry name" value="Znf_RING_synoviolin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF184">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25563">
        <property type="entry name" value="TPR_SYVN1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="14 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="12" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="7"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="292"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="337"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="444"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="499"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="563"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="457"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="499"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="516"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="571"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="659"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0581859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="668" mass="74366" checksum="067E1C212E1C1A86" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGH0</accession>
    <name>A0A8T0IGH0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HORMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G267800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGH0"/>
    <dbReference type="OrthoDB" id="21254at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016035">
        <property type="term" value="C:zeta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:DNA damage response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.900.10:FF:000003">
        <property type="entry name" value="Mitotic spindle assembly checkpoint protein MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.900.10">
        <property type="entry name" value="HORMA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003511">
        <property type="entry name" value="HORMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036570">
        <property type="entry name" value="HORMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045091">
        <property type="entry name" value="Mad2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11842:SF10">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02301">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56019">
        <property type="entry name" value="The spindle assembly checkpoint protein mad2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50815">
        <property type="entry name" value="HORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HORMA" evidence="4">
        <location>
            <begin position="10"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="23298" checksum="A10E589C04CDDCC3" modified="2022-10-12" version="1">MEVVRLSDRGDVGELVCEFLEVCIHQLLHIRELYPAEIFERRRHFNVPVQWARHPDLREYIHSAVTNLHSCIQQGVVDKIILSVVDNNQVLVEKFVFRLGLKQLSSAGVPAQHLEFALRGFLLKISVSNELLSPLPLDCSWEVVAHLKSASLDTVKNGQLWTPADDEGWDQSFTITSIKSMQSSYLDMQLYVERSVERATNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGX7</accession>
    <name>A0A8T0IGX7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G036400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGX7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="LIPID-A-DISACCHARIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372:SF5">
        <property type="entry name" value="LIPID-A-DISACCHARIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="559" mass="60732" checksum="0E88792464A21357" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJC7</accession>
    <name>A0A8T0IJC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="16">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_3G069800</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="16"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJC7"/>
    <dbReference type="OrthoDB" id="5326588at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="4" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="11" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="14" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="221"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0582563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="453" mass="52821" checksum="BF3BC69C57841BDD" modified="2022-10-12" version="1">MGRGRTPTRKEYIESSQYQNDSTSTAHSRRVNIIAMTTVMWLAPVVVVCLWHTIVNLDGSGLNMWKYWKAYSFDGVRKIWPMPSFYAIKLILTFAVFEALLQIYVPGERHISIVSPTGNRAMYKKNGFTCCVITLFVFYFAYKEKHFAPAGVYDHLGEIYSSLIILGTITVALLFLKGYTYPSSSDWGSTGNVLVDFYWGLELYPRLGKDFDLKLYFNSRFGMMGWGCLVICFVIRQWEQKGKVADSMIVTSVLMLTYICKFYWWEGGYLNTLNMMHDRAGYYNIWGSMVWLPAVYSSPALYLVNHPVQLGFWVSLYIMFGGLVCIYTQYNIDHQRQEFRETHGKAKVWGIFATKIQAHYVTEKGEHKQTILLASGWWGLARHIHYIFEVGAFFFWSVPALFAHATPYFSLFFVTMFLIDRCERDDKRCKSKYMKFWDIYKKKVPNKIIPLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILF6</accession>
    <name>A0A8T0ILF6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G160000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILF6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052356">
        <property type="entry name" value="Thiol_S-MT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036:SF1">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45036">
        <property type="entry name" value="METHYLTRANSFERASE LIKE 7B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="177"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="37189" checksum="8A41A0D18ACB4AD1" modified="2022-10-12" version="1">MATSMAFTSPLALNFPRSSSNTLPSCSASLLNAFHVSTHLQRLPFFTSPTLAAYPERMMFATGRFACGSPRIAPNSASVQHHQEQSVCTCCTRRAVLTSLGGAIVANVTAERTSLAVEGSIPSADMIREAVYPARPEWYEEYFATSMNTTMRSYEAEIAGYKRELFSRLGDNVKTILELGIGTGPNLAYYGGRPSITSVIGVDPNVKMARYAEAAAVAAGLSPAQFKFMPAVGEGLPLPSASVDAVICTLVLCSVSDVSSTLKEVQRVLRPGGMFLFVEHVAAPEGDSLRFWQGLLDPVQQLVADGCHLKRDTLGFIEAAQFASVDARRVTVNGASLIGPHVVGSACIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQB4</accession>
    <name>A0A8T0IQB4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AtTam37 zinc finger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G050700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQB4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056892">
        <property type="entry name" value="Zf-AtTam37"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36404">
        <property type="entry name" value="EMBRYO DEFECTIVE 2737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36404:SF1">
        <property type="entry name" value="EMBRYO DEFECTIVE 2737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25112">
        <property type="entry name" value="zf-AtTam37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AtTam37 zinc finger" evidence="2">
        <location>
            <begin position="74"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="50858" checksum="99A79F5D9A6CA506" modified="2022-10-12" version="1">MNKVDIGRVLAVVKQRSGEFVGAVKDTAVEFSWDLRDAAEAGFGVPKLISSVASLSVAVVAASGTAAVMFDGAGKVFGKRECIECNGWEGLRCTMCEGKGLVHYFVNNIEDGQSDSVQSLAAAISSGNASFGYVPATMNSGHPLPRRECPTCDGTGVITCKKCKGESWKPKLNLDDIMDVPWKAWNVYRKITPPTESEDKLMANPDLARWMMFDKPAIEDGIEYDEDVKEKMWLEYKEKRSYDELREKVERREPGWEVFQQGLMNINPDRARVDPLVVQNVPYYKAQLQVQAEIDQLQPPPRPANWGDLKMPLSEADWKKEDLKDPRVREEMETLLRTQEGIYGALLDSAWEKQWRDQQFEAISKAKIEAYLQAKQEEGRNPRPSPVPSKDEGAGKSSPATTARDSKASAQKGGGKKAPDDKKKRERQERAERLARQAAEREAALAKSKAARGTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQJ5</accession>
    <name>A0A8T0IQJ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AFG1-like ATPase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G255500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AFG1 ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF040713">
        <property type="entry name" value="ZapE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169:SF29">
        <property type="entry name" value="AFG1-LIKE ATPASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12169">
        <property type="entry name" value="ATPASE N2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035804054" description="AFG1-like ATPase" evidence="4">
        <location>
            <begin position="19"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0585071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="55254" checksum="CE9BBEF54A9FE914" modified="2022-10-12" version="1">MAWHARSHSFKFPLLTMALRLPTMRQACRSGVMGAGVAGEWVQLRYGSGGSGPLALYRDLVQRDELESGNFAQERAVEALEKLHHEMKQAEEARWWQPMVGWYRPPAKLGMYMHGTVGTGKTFLMDLFYNQVPVRRKRRVHFHSFMLDVHKRLHKHGRVPNAVQVVALQLFEQSRLLCLDEVEVTDIADALMLKRLFEVLWPMGIVVVATSNSTPDQLYQDGLNRHLFVPFIRQLKEYCSVYSLNSVDGNDYRRRHAWSGHLYHCSLEDNIDNVMNQIVLKLTGGAEMTPQPIMGSMGRLFHILASKDVARASFSYLCKSAFGAADYIAIAENFTVLLLDRIPSLADPSCENEARRFINLIDILYETNTILICSAAVPPDSLFSDLSQMDEPAKEYIVDAIEDTGIRIVGEGGSSGRSTLMIGNMEWSATGRQGASLADLAGASFTRKAAPRCVSRLLEMQSSLYVARARSVHIKSQLEQLALANIENRCQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRW1</accession>
    <name>A0A8T0IRW1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G092900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="17048" checksum="2C1529D98F8C42ED" modified="2022-10-12" version="1">MDIRSILLTNPEQERRHMNWTVIPRNNVQKELRNSNAIEEQNLQDILNLTTAQLLQFIPANSSERIQTLILYVDTNDIRMRRNLELLSQSAARPFSHIQTALQLKLSIEQIDHDMRTNVDKAHICEAYLNPKMVFPQNWCKEKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISG9</accession>
    <name>A0A8T0ISG9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G003900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17190" checksum="79C21F12D64F1873" modified="2022-10-12" version="1">MLNPAFGDEVHAQIDSIRGGDWSFSLRRHNVRIRRHRKPMPSRLLNPSPPSPTACTCAIHNQPLSSSPPNPISQSHTHGTPTSIRPHLGPIPSQIAFSEPSAEAPALLTENIARLACTVFKPETELPDHSHHTSPQSSTFQPKIRFPTLELPQLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISM2</accession>
    <name>A0A8T0ISM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G028300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="7913" checksum="6A954B3E71D8DC8C" modified="2022-10-12" version="1">MVGAEVRWWSANTVAVVTGSNKGVGYEIARQLARNGLTTVVTARDVSRGTKAVEALRTEVGSDRIALDTLTPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITP3</accession>
    <name>A0A8T0ITP3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G092500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="38" mass="4358" checksum="2E369FA0A5D937AA" modified="2022-10-12" version="1">MMPRSLQSASLVFSWMLLTKLKPTKESMDLASLLEDMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUR7</accession>
    <name>A0A8T0IUR7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G124700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15204" checksum="F72756EE3E60AE72" modified="2022-10-12" version="1">MQEESFICSSCSGYIGEYNVVAADSVPCDVSLLPSFRTVDIAEASQLPRVYSSRRLLQRTYNLGCAYQVRSRYPNGCRSGQSCYDGNRCRAAADCCSYRCLKGRCCGSYGGMNCENGNWNSGGNGNNGNGRNAQVNGRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVR9</accession>
    <name>A0A8T0IVR9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Septum formation inhibitor MinC C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G152000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVR9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="SEPTUM SITE-DETERMINING PROTEIN MINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108:SF1">
        <property type="entry name" value="SEPTUM SITE-DETERMINING PROTEIN MINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="Cell-division inhibitor MinC, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0717">Septation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Septum formation inhibitor MinC C-terminal" evidence="5">
        <location>
            <begin position="126"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0587255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="381" mass="40754" checksum="DA822991CFA033E0" modified="2022-10-12" version="1">MGFNNCLLFRSRSICLLASAERCGLPRDNLVPSCSLVSFKRCGMRSGISAREGFGDGILEWSGFSRGLLALHSGFLERRIRESCLIPHRSHGFTISAMSESRDSENGAQMAFTEAATSSKYPCMYVKDTVYSGETIEYSGNVVVLGDVQEGGAIMADGDIVVLGRLHGDVHGGRNGDRDAVVYATQLDACHIRIAEAIALVSKSQFPGCPVIASVHEDGTLGIRAAVQESIDNKEAKTSRVSESKDQASSNRPAQLALFTGVYISLVGVALLVFPASLFGVLFDVRSVTVGWIRVGAILAVVFGVYYIGTAVGDMRGSSGARAFYMSTVVGRVFLFFGFCWLVAAGAAQRALLLLGIVNMLGAMSMFIALRQDSNGRVLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXK8</accession>
    <name>A0A8T0IXK8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">KC19_2G246100</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXK8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000542">
        <property type="entry name" value="Receptor-like serine/threonine-protein kinase At4g25390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0430">Lectin</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 22" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035902224" description="non-specific serine/threonine protein kinase" evidence="22">
        <location>
            <begin position="30"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="368"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0588480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="768" mass="85480" checksum="EC3DF65C4432DBB4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXX8</accession>
    <name>A0A8T0IXX8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G255300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXX8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000126">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF18">
        <property type="entry name" value="FLAVONOID 3'-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9 10" id="KW-0349">Heme</keyword>
    <keyword evidence="7 9 10" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="26164" checksum="413FB90349E33709" modified="2022-10-12" version="1">MMRMQELLIGGTETAATTVEWAMAEMMTHPDVMKRAQEELHAVVGRDRLMQESDVPNLPFLQAVVKETFRFHAPTPLAVPRASSQAAEAWGYTIPAGSQLLLNLRAIHRDPAFYTNPDEFDPQRFLDRPEVNHLSGFSFYELIPFGTGRRMCPGVNLGNTMVHLMLGNLVHNFDWSFPKDQSVETCQRENLEEIFGLTACRKEALRLCAKPSDHIQSMLRNTCSQSTQTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZ73</accession>
    <name>A0A8T0IZ73_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine-threonine/tyrosine-protein kinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G210500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZ73"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine-threonine/tyrosine-protein kinase catalytic" evidence="5">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0588036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16096" checksum="4F0BC341F5ECCF3B" modified="2022-10-12" version="1">MCHGQLSDKADVYSFGVLLLEIVSGKRNRDLSMPEDEVYLPNWAWKLHKESRLLDMKDPSLVLGQNQAEEVQRVLETAVLCVQSAPEKRPSMFLATAMLAGQVSVDALPSIEEIDESWLQGITLQDLYSDNGIRMLMSSSASTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZM1</accession>
    <name>A0A8T0IZM1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G215800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RLP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000233">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase TDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000213">
        <property type="entry name" value="Tyrosine-sulfated glycopeptide receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052:SF8">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE FLS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="554"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0588101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="610" mass="66106" checksum="AA4A64C06299896B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0V3</accession>
    <name>A0A8T0J0V3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G030500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="13104" checksum="9997369A8B36B307" modified="2022-10-12" version="1">MIDSAASSRRYSNLVVMDVVLSVNELLHRAFYTVAYLGIIINYLTFRVATTSTLRNWRSCHAVAERLVFSFRVRHVSKLCSYLQLLLAKLSCPWLPSVLLNVSVRPRSFDDRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J218</accession>
    <name>A0A8T0J218_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G286100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J218"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001488">
        <property type="entry name" value="Putative helicase CHR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031053">
        <property type="entry name" value="ALC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47157">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47157:SF1">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="36"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="332"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0589018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="502" mass="55160" checksum="37114175B464A182" modified="2022-10-12" version="1">MQLRKACSHPYLFDGVEPEPFQEGEHIVEASGKLKMLDMMLKKLHAGGHRVLIFAQMTRTLDILQDYLEYRRYSYERLDGSVRAEERFDAVRSFSADHSKRGGAPSSGSAFVFLLTTRAGGVGLNLVAADTVIFYEQDWNPQADKQALQRAHRMGQMSPVLAINLITPHTIEEVIMRRAKRKLELTYNVIGRDDVDLEAHGPASAGSADLRSMIMFGVNTLHKSGGTNDVEIVDDSALEAIVDAALAQRGKTGSDLSSSTEFGNVGLVTLDSQGDQAENFYKYEGKDFTKPADKALLESWAVDANASKGNEVDTRRSRRGRTSALGSDEDQENARAQKRQKAEDKKRSKWQSLGYHSLAIDDPGVGLQPDSSDDETGNDVNFVIGDCTQPVTTTKDEPCIILSFVDNSGTWGRGGMFDAVARLSSKVPEAYEAAYEAEDLHLDDLHLIPVSGATRFVGVAVIQTYDRRRKIPRSDISMTAFETCLRKVVTAAKAHSGTAYAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J349</accession>
    <name>A0A8T0J349_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">acyl-CoA oxidase</fullName>
            <ecNumber evidence="4">1.3.3.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G017400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2</text>
            <dbReference type="Rhea" id="RHEA:38959"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58856"/>
            <dbReference type="ChEBI" id="CHEBI:65111"/>
            <dbReference type="EC" id="1.3.3.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acyl-CoA oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.6" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J349"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003997">
        <property type="term" value="F:acyl-CoA oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033540">
        <property type="term" value="P:fatty acid beta-oxidation using acyl-CoA oxidase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000007">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000005">
        <property type="entry name" value="Acyl-coenzyme A oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055060">
        <property type="entry name" value="ACOX_C_alpha1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012258">
        <property type="entry name" value="Acyl-CoA_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002655">
        <property type="entry name" value="Acyl-CoA_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909:SF378">
        <property type="entry name" value="ACYL-COENZYME A OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10909">
        <property type="entry name" value="ELECTRON TRANSPORT OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01756">
        <property type="entry name" value="ACOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22924">
        <property type="entry name" value="ACOX_C_alpha1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0274">FAD</keyword>
    <keyword evidence="7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="11">
        <location>
            <begin position="164"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="12">
        <location>
            <begin position="311"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-alpha1" evidence="12">
        <location>
            <begin position="398"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase C-terminal" evidence="10">
        <location>
            <begin position="506"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF22924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0589378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="675" mass="76166" checksum="57268FA2D685111E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5G4</accession>
    <name>A0A8T0J5G4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G076900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF62">
        <property type="entry name" value="AMINOTRANSFERASE CLASS V DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="1">
        <location>
            <begin position="263"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="672" mass="75501" checksum="A57424B2ED117F15" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5N6</accession>
    <name>A0A8T0J5N6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="12">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_1G158800</name>
        <name evidence="16" type="ORF">KC19_1G159300</name>
    </gene>
    <organism evidence="15 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 13">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="12"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5N6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000003">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000006">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1260:FF:000017">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="entry name" value="Phosphoglycerate kinase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406:SF23">
        <property type="entry name" value="PHOSPHOGLYCERATE KINASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="Phosphoglycerate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0591214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0591219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="52596" checksum="508BDB2F6BF6D169" modified="2022-10-12" version="1">METLAMGAAVAASGVAARATAQSAQTSRVAAASAFVGRSVRVSRSGAGFAAASQRARVVRIVAEASKTEQLSKTAQLPEDDGKSDVQRPATQGSDRKMNIKDVPVEEFKGKTVFVRADLNVPLNKGTITDDTRIRASLPTIEFLTKAGAKVVLASHLGRPKNGPEEKFSLKPVAGRLTELLGKNVELAPDCIGEEVKSKIAALKEGDVLLLENVRFYKEEEKNDIEFSKKLSENIDIFVNDAFGTAHRAHASTAGIADYVSSRLAGLLLEKELEYLAGVVKKPTKPFVAIVGGSKISSKITVIESLMNVCDKVILGGGMIFTFFKADGKSVGSSLVEDDKIELAKNLVKMAKEKGVELILPVDVLAADKFAPDANVKKCSASEIPDGWMGLDIGPDAIKQFEAALKDAKTVLWNGPMGVFEFDEFAKGTYAVAEAMAKLTKEGAITVVGGGDSVAAVEKAKLADQMSHVSTGGGASLELLEGKVLPGVAALDDVRIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6F9</accession>
    <name>A0A8T0J6F9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G151700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6F9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF227">
        <property type="entry name" value="RETINOL DEHYDROGENASE 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="424" mass="47521" checksum="36F06E7CCD6CB829" modified="2022-10-12" version="1">MTTASDSLQMFQHHRTISVCKNRGWPGRVQAMETSSEEQAGAAQQRGTKMGSEDGARKWDVFRLGNLLRMAVVWILCLFYSYIQYHVIRLQLPHRKHEFQSLNFRFRSSQESKPACIVTGASSGLGRETASALAQRGFHVILAGRSLERLEVVRAEIQTQSSSASCQALAVDLTSVPSILSFTRTVKELFESHDSPGTLQLLVNNAGVIAASQRWTEDDCDVTMASNYIGHYILTHELLPLLQKNAPQARIVNLVSFTHRALQRDQIDVSQLRNGGIQQKPADRSYYPLAKIYETSKLFLILFSYELHRRGFSNTEHKDRVSVMAADPGFASTNLLREVPNWLVQLSFIVMRLLRLWQSPTAGASSVVAAATAPWEVSGKYVFGNQGLFCKSTSLTYDEQLGRSLWEASEGICTELIDKHSKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6T8</accession>
    <name>A0A8T0J6T8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G134400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6T8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="AntiFam" id="ANF00205">
        <property type="entry name" value="Shadow ORF (opposite nemA)"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="24349" checksum="AD9E28E4D73579E1" modified="2022-10-12" version="1">MVETGSLIGDIQRSTHLEPLHQIRVGYEGPSEPHHVRISGAHSFVSRFTGVAPTDQQGSCSLLRQMAILGRPGEVIHNVGELGLCQVDVRQVELIELCEQVREEIFGVCVGPSCVVHTEWRDSNGCLVCTYFVDDSVGYLQQEFAPVLHGASVFVRAVVDGVLHERIQQVAMCSVYFTPVKTFIEKCFEHLENLFHLRPGCNLPSNVQLFSFPFLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7I8</accession>
    <name>A0A8T0J7I8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G179200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7I8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="408" mass="47166" checksum="8F6DA25D6E1E18A2" modified="2022-10-12" version="1">MAPRPSRNLKEDATLLGDIKDDVAMDPTLWGNLKDYVAMEIIYAKVPFHKFFQLRLVCKEWNHLAGDRKFLEDQFKEYLVPEPYFYFRGGREYLVPSPFKLIFQDGRFTNGFLTFDVTSEDVSWIGLYNTWKDRGGCFALNGLIYSETVPSPHYLWAPKKTPHILQKWAESRRQEVFNIHTRVRHQLPPPQLTTAIPVVGMLVDTSVRPYGFKVIQGCGDLGTQIFDSNTNAWELRPSRLPAGIAARLDSFRSMSPGCSHHSSVNCNGLLFIATEDRKEILVYNEKEDVWSTLCAPRNVGWRLELHIGSWHGTLFSLQQRPTVCGSTWDVVNPSRQEWEPYDRMPADLRDWLLNDGKSSKVDINYSKNYVFMYNQSTQEDCKNRIVLYELATISWKSFTFRSGSYLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8L0</accession>
    <name>A0A8T0J8L0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G205800</name>
        <name evidence="2" type="ORF">KC19_1G206100</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7365" checksum="82B945B4644D8B5D" modified="2022-10-12" version="1">MQTARDNYKQQLGELRLFSLQFSKVSTRESAHGRDFRCNVKGSCLRSSLLQGAGRTRRMRGSRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8Z8</accession>
    <name>A0A8T0J8Z8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ADP-ribosylation factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_1G231300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the small GTPase superfamily. Arf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8Z8"/>
    <dbReference type="OrthoDB" id="2011769at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04150">
        <property type="entry name" value="Arf1_5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000548">
        <property type="entry name" value="ADP-ribosylation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045872">
        <property type="entry name" value="Arf1-5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024156">
        <property type="entry name" value="Small_GTPase_ARF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006689">
        <property type="entry name" value="Small_GTPase_ARF/SAR"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11711">
        <property type="entry name" value="ADP RIBOSYLATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00025">
        <property type="entry name" value="Arf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00328">
        <property type="entry name" value="SAR1GTPBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00178">
        <property type="entry name" value="SAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51417">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 14" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11 13" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10 14" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 14" id="KW-0519">Myristate</keyword>
    <keyword evidence="5 11 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="24"/>
            <end position="31"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR606689-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU369003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0592177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21641" checksum="F8799AAF137BFCAE" modified="2022-10-12" version="1">MGNTFRKLFDSIFGNKEMRVVMLGLDAAGKTTILYKLHIGEILSTVPTIGFNVEKVQYKNVEFTVWDVGGQEKLRPLWRHYFNNTDGLIYVVDSCDRERISKAAVEFQQIINDPLMRNSAILVFANKQDMKGALDTSEVCEQLGLFNLRNRRWQIQGTCAPKGEGLYEGLDWLATTLKQMQAAGISTSVKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9Q3</accession>
    <name>A0A8T0J9Q3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G254200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9Q3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="17427" checksum="872FBC5808C64B2C" modified="2022-10-12" version="1">MRRHEKETLRRLKHGMGRLPWLSYASRIDQSKVVRCLPALFLTFYHVFGIDGSKSMNVLALVSENVFWRDVWDYMMLWRWAWKSGQKLAGRTTVQRSQWATQFYLYCTVLCSHLVSSPFSMCVVEIGHLQLRCAHVTKQRVFGHSSAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAS3</accession>
    <name>A0A8T0JAS3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G297900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="510"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="511"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="761" mass="82567" checksum="B41A141A5EB01202" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB61</accession>
    <name>A0A8T0JB61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Rho GDP-dissociation inhibitor 1-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G276600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rho GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB61"/>
    <dbReference type="OrthoDB" id="1683373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005094">
        <property type="term" value="F:Rho GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007266">
        <property type="term" value="P:Rho protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.50.30:FF:000004">
        <property type="entry name" value="Rho GDP-dissociation inhibitor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.50.30">
        <property type="entry name" value="Coagulation Factor XIII, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000406">
        <property type="entry name" value="Rho_GDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024792">
        <property type="entry name" value="RhoGDI_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980:SF3">
        <property type="entry name" value="LD16419P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10980">
        <property type="entry name" value="RHO GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02115">
        <property type="entry name" value="Rho_GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00492">
        <property type="entry name" value="RHOGDI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0592725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="253" mass="28410" checksum="FBACFEDD44D9BE87" modified="2022-10-12" version="1">MSKTVSSWFGRTHSKSLSKDLNKQDTQSSEQDKENKENSSDQDQKLTKCESLPTNLISFESDDDTEEHEAPCAEFNAELGPLVSLKEQLEKDKEDESLRRWKAQLLGVASDDDAGDGFVEPEVNVVSLGVISKGRPDSDFPLPLGTNSRGYTFSLKEGSTVALKYVFTVRNNIVSGLTCVNTVWKAGFQVDQTRDMMGTFAPQQEPYVHIAEEEVTPSGSLARGAYTARKRFIDDDNRVYLDLDYSFEIRKEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JEZ7</accession>
    <name>A0A8T0JEZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G315800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JEZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="396" mass="45629" checksum="D63933D23CE997CB" modified="2022-10-12" version="1">MVKRKRRKNGGERLRVVDNLDHAIQGEHLPKAIVKRNRNGDEIPKVVEKMGDAIEGEHWSKGKGKDDPYLCLVSVNNRKCPYGPFKHKYHFNEHMKKAHKLELEKLKPGPKEDENDKTKKKKKKTTKNPNLKIMTTSYLREKKEFEKKKEAWSIRAQMSWKKLEERARKEPPPGQCRLLLSLIKNGGKLEEFLGVESLGKGNLNFSKIEKLHNLEALADLVRSNPQNNKKVTKDFQELFYYSKWERNEKERKGLVASIVKWHRAKSMKNIYLFLKTKFYEMENVSRMERVEVACDSYRAKHGLGDDIFNSGEEGSGEDEVEEDTYEEIVSQTDDDDDGDNHDDEEEHEEDGGANGEEDEEREDNARDGGVGGNGGIEGEGSEVREDQGNGEDVYDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4N8</accession>
    <name>A0A8T0G4N8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_12G077300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4N8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000017">
        <property type="entry name" value="Histidine acid phosphatase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016274">
        <property type="entry name" value="Histidine_acid_Pase_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000894">
        <property type="entry name" value="Acid_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035890071" description="Multiple inositol polyphosphate phosphatase 1" evidence="17">
        <location>
            <begin position="33"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="68"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="273"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="440"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0554256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="510" mass="56540" checksum="FE97EC26371314E7" modified="2022-10-12" version="1">MMGRGGGSGMVKALGLLGFMLVASLWTVGAESADEFDVRQHLSTTTSYAAGNSIRYGDETVESTPEGCVPVHINLVARHGSRRPTKKRIAELEKFAERLRVLAKGAAEAQNESTISPPAWISDWKSPWSDKQIGGELLPKGEEEHYDLAQRYKIKYPEIFSEEYHPDVYPIIATQVGRSAASSVAFGMGMFAGQGTLGPAKQRAFSVITDSKGHDIHLRFHDTCIAYKESKKLRKPKVAGWQKHVYDTVAERVKGRYGMAVTIDDVTSLWLLCKNEASLLDVVDQACDFFTPEEVELLEWADDLEMHYLKGYGESLNYRMGVPLLGDVVDTMDRAMAADQSHKVVEKARLRFAHAETIIPFSCLLGLFLEGNDFKEVQSEKALEAPIMPPHHRLWRAALVAPFAANTALVLHKCPADDGAGVKYLVQALHNEKPVIMPACNGTYFCPIETFKERVVAPHMKHSYESLCTPQVVHKPVHQSFLGKVFSIPSHLFRWLFSSAPGQGTCHSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6C3</accession>
    <name>A0A8T0G6C3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G056600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fl(2)d family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6C3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016556">
        <property type="term" value="P:mRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000381">
        <property type="term" value="P:regulation of alternative mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033757">
        <property type="entry name" value="WTAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217:SF0">
        <property type="entry name" value="PRE-MRNA-SPLICING REGULATOR WTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15217">
        <property type="entry name" value="WILMS' TUMOR 1-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17098">
        <property type="entry name" value="Wtap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="345"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="107"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0554017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="42624" checksum="92EC141A0500D20D" modified="2022-10-12" version="1">MCNCVHGLEKLILGLTLMNAIVIAGVELIARHVLMLLFLFYFLSMREDSFDFDGDTGGENGLTGVKREFADLDDDEEELYPAKKIYSSSGPGSDHATTTILNLRSSLDERDSTIAALKASLDAANEELEKWKNAFAQDPSLPPGATDDPAVVVQAMQKLQTSESQLKEQILTAKRREGVLLVKLASTDQEVVDLKSTVHDLKLMLKPSIQQTRRLLLDPAIHAEFTRMKKELEAAEKRVKELKDDLAAVQFTPHSKHGKLLMAKCRTLQEENTEIGREASEGKVHELDTRLAAQKYLNTELRRCYQELYETAEDSNYELERSQQTVYNLQRQLQKKDHQLVELRKQIDEQSRREDPTPIREDEDQQVLEKDAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8R7</accession>
    <name>A0A8T0G8R7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G029800</name>
        <name evidence="3" type="ORF">KC19_12G030100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8R7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14083" checksum="CDA575B8CE654207" modified="2022-10-12" version="1">MALKPAIVSRNQINDHAPQRHFTLLTMLNHRPNATLSLPAPLIRKTPWTTLHHNAQTSQALPTNALTSTNQLDTTTTNPPQIRPTSRASIYLLHQSTTPSPQPRKLCRPHSVHVLTTARTQLTCQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBE9</accession>
    <name>A0A8T0GBE9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G050200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006747">
        <property type="entry name" value="DUF599"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31168:SF1">
        <property type="entry name" value="DUF599 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31168">
        <property type="entry name" value="OS02G0292800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04654">
        <property type="entry name" value="DUF599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="249" mass="27719" checksum="D56673FC2B956F34" modified="2022-10-12" version="1">MGWDSRYLDIVLVPLGLFMLAIYHLHLWFKVKYHPESTVIGVNHINRQAWVNNIMSDSMKNGVLAVQTLRNSIMASTLLASTAITLSSIIGALVSSTSGGSSKTLKNFVYGETGNITSTLKYLCLLLCFLFSFVCHVQSIRYASHASFLLSIPVGDNAPGLTPEYVNQFIYRSQNFFSLGLRGYYFSFPLLLWIFGPIPMFVCSVVMLFLLQTLDRAKEFNLTFKILSSPDDSKGENGGTGTFHQILSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD00</accession>
    <name>A0A8T0GD00_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_11G013700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD00"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23117">
        <property type="entry name" value="RING-H2_TUL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000338">
        <property type="entry name" value="E3 ubiquitin-protein ligase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050731">
        <property type="entry name" value="HRD1_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763">
        <property type="entry name" value="RING ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22763:SF162">
        <property type="entry name" value="TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="406"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="536"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="16">
        <location>
            <begin position="599"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0555929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="649" mass="73694" checksum="3004C422A40AD3C2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDE2</accession>
    <name>A0A8T0GDE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G025900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044800">
        <property type="entry name" value="LEC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140:SF81">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="288"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="232"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="396"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="407"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="426" mass="48168" checksum="D67E07B977F906DC" modified="2022-10-12" version="1">MEESIANPWLEDLRDFARTDDEYFPAGQNQLESRSLQPSAASHLEFSNSSSPTFLCGTAEPYAYFDPYLRTHMQTMAFKGVQVHDSFRDKGEGPLSQALEQLLPCSIHGEVYSGTSGEPLHQLPGWTQHNGMMEDWNPSSSCSLGMESSSTKPAKLQINHEPWMMEMPSLCPTSSLEMSPVNHLFHPDNMFTSFEDHAEQSQRPRSASYNSNEPVAVNRKAAARKNRILLRQKSAPHQRVTSQCAVQDANGSGSPRPSKKAYSNKIPQELLMNINVQGRNMDPLRFILHKVLQPSDVNNLGRIVISKKEAEAHLPYLSLKEGIFITMEDFDTSDLWTFRYRFWPNIKSRMYLLESTGEFIRAHQLKKGDIVILWRNNLRDTFVIQALVLPNGCASTTQSPDHSAAVDLREEAREDDIKGKTKARRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDI3</accession>
    <name>A0A8T0GDI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Tyrosyl-DNA phosphodiesterase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_12G157500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosyl-DNA phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017005">
        <property type="term" value="F:3'-tyrosyl-DNA phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22671">
        <property type="entry name" value="FHA_APTX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09122">
        <property type="entry name" value="PLDc_Tdp1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000028">
        <property type="entry name" value="Tyrosyl-DNA phosphodiesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000031">
        <property type="entry name" value="Tyrosyl-DNA phosphodiesterase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010347">
        <property type="entry name" value="Tdp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12415:SF0">
        <property type="entry name" value="TYROSYL-DNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06087">
        <property type="entry name" value="Tyr-DNA_phospho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="576"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="578"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="11">
        <location>
            <position position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR610347-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0555272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="735" mass="81520" checksum="6CC019AFC7F222CF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE31</accession>
    <name>A0A8T0GE31_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fibronectin type III-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G048200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000001">
        <property type="entry name" value="probable beta-D-xylosidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fibronectin type III-like" evidence="5">
        <location>
            <begin position="573"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="652" mass="71747" checksum="378BE62D9E04FCC1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFE2</accession>
    <name>A0A8T0GFE2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G171100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002812">
        <property type="entry name" value="DHQS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563:SF6">
        <property type="entry name" value="USPA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="695" mass="77504" checksum="2A4941B26C020C2F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFV3</accession>
    <name>A0A8T0GFV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="21">Nuclear receptor coactivator 6-interacting protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="22">PRIP-interacting protein with methyltransferase motif</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">KC19_11G164000</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="25 26" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="25 26">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="14">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="20">May form homooligomers. Interacts with CREBBP/CBP, EED/WAIT1, EP300/P300, NCOA6/PRIP, PPARBP/PBP and SMN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Cajal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
            <location evidence="3">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFV3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000066">
        <property type="entry name" value="Trimethylguanosine synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11" id="KW-0804">Transcription</keyword>
    <keyword evidence="10" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WW" evidence="24">
        <location>
            <begin position="157"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="304"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="332"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00064494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00079339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00081504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0557883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="746" mass="83318" checksum="86B19894F0246D6A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHW4</accession>
    <name>A0A8T0GHW4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">W2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G076400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BZW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11560">
        <property type="entry name" value="W2_eIF5C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000028">
        <property type="entry name" value="ARM repeat superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051245">
        <property type="entry name" value="eIF5-mimic_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057397">
        <property type="entry name" value="HEAT_5MP1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043510">
        <property type="entry name" value="W2_5MP1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003307">
        <property type="entry name" value="W2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208">
        <property type="entry name" value="BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14208:SF2">
        <property type="entry name" value="PROTEIN KRASAVIETZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25504">
        <property type="entry name" value="HEAT_5MP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02020">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00515">
        <property type="entry name" value="eIF5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51363">
        <property type="entry name" value="W2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="W2" evidence="2">
        <location>
            <begin position="246"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="411" mass="47181" checksum="6FE662A0A2B132E1" modified="2022-10-12" version="1">MSSKEKPTLGGTRIKTRKRNIAVPLDTATFADAVVQIYNEHQGDLELIAKDVDGSELDFSRYGDTFFEVVFTGGRNQPGTTKPEEGERHPYSVLNCEDTRESILPVVLFLQKIIRRRPFMIKTLENVMKRLLQSLELFGTEDRKKLAIFTALTFSQKLSGLPPETIFSALMSDSLISKGIVLYFVTDTFKVYLVENSLDDLVSLLKRAKMDDRLLDLFPMQKRSLEGFAEHFNKEGLGVLVDYNTKKVFDVKLKELRTTMTDMIAEDVNVNEVIEMVKLRRKEVTLPDVDVIRTIWDSIMDAVQWSGKNQQQNSNMALHQVKQWGKLLGAFCTNGKLETDLLYKIQIHCYEDAKLMKLFPEIIRALYDQDVLAEDTILNWFKKGSNPKGRQTFVKGLEPFVKWLEEAEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIC0</accession>
    <name>A0A8T0GIC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G084300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="21920" checksum="0E8B399B6C91BDB4" modified="2022-10-12" version="1">MHCHLTEALKNQPQILTNITCSLLYAWGGAEISSVRKLVSWFSLLQLATAMCWSENVPEKFSCFEMVANLGCRHRLVFHGRGIVGLLLLLQLSSLSVYSQPVKVISMQMYELYGLRLFWFAWNQSTPDPETNLAGWRTFDYRYYGNYGFTRHDDPCYGKQWRGLVCAQQRVNDTYYTAQIIGIVLQDVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIL7</accession>
    <name>A0A8T0GIL7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G159600</name>
        <name evidence="2" type="ORF">KC19_11G142700</name>
        <name evidence="16" type="ORF">KC19_1G046700</name>
        <name evidence="15" type="ORF">KC19_2G248500</name>
        <name evidence="11" type="ORF">KC19_4G007800</name>
        <name evidence="12" type="ORF">KC19_4G218300</name>
        <name evidence="13" type="ORF">KC19_4G218500</name>
        <name evidence="14" type="ORF">KC19_4G263500</name>
        <name evidence="10" type="ORF">KC19_5G204800</name>
        <name evidence="4" type="ORF">KC19_7G040100</name>
        <name evidence="5" type="ORF">KC19_7G111500</name>
        <name evidence="6" type="ORF">KC19_VG081700</name>
        <name evidence="7" type="ORF">KC19_VG081800</name>
        <name evidence="8" type="ORF">KC19_VG263400</name>
        <name evidence="9" type="ORF">KC19_VG276200</name>
    </gene>
    <organism evidence="2 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 17">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0567117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0572290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0572291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0574456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0574612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0578235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0581022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0581024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0581591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0588510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0589768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37702" checksum="4C7D754A902F279D" modified="2022-10-12" version="1">MGNCNHKFHITCIAKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTANDAGMDDFSWMTHDHEVEMRASEIPDAKDREFFCRNFGGHWSIHRNRFFRFPKPEVVVDADGKRREVERDYGQLDEYKMYDRTPVGRALVLAKLEEAIQHRRTFTEESFKYSDLDYWVITKKFDDALHKIVNDWRRALRAEDNSSRWSRNRIEKIVQETVAKIDKAKELWNGKNSKKRNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJN2</accession>
    <name>A0A8T0GJN2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MULE transposase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G050900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJN2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018289">
        <property type="entry name" value="MULE_transposase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10551">
        <property type="entry name" value="MULE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MULE transposase" evidence="1">
        <location>
            <begin position="286"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="504" mass="59830" checksum="3079F6A020AAA6E8" modified="2022-10-12" version="1">MPRRKEDPIVPQSPPLGPISFEDLVWKQGARKGYGNKTTIMRAYIPFDRVGDFLRGQTCEGGIEVGWNVAERIQGTHVLRPQVDSYIEHVYYECPFGPKDLRGDPPHPHSKKRGCLARFSIKQLLLRPDVAEVAYYQVDHNREDGTPAHGLEDKDSIGRKSAYQPRMSLELKKWIKTRLSEGFTAKQVYEEHRRNWIERRKMKCPEIRDDFVELRDIAYYESRLKMGVWRRHPNDFESVKMWIKEHPENVFMWHEKDDVTDLPFILGIQTPWQKEMMLKYGHNGAIAMDATFGTNVPKYPLYSLLVFDHWRNGIHVAWVLSSRSSEEDLVMWLEPLRRHLEGTRLDFLPSCFIVDDAVEQRNALKRAWPESEVPIYLCAFHVLKNWKNHIWTKVPNLGSLRELVYRQLHSLLYMPIEYQETEEDFLKRARVRSKNMFNFLYIKSMEEYIEVYYDHQEMYLIGHRRNPHSNQDTQASIESYHAALKRWMKIDNHQLRGRRMDSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKM5</accession>
    <name>A0A8T0GKM5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G015400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10775" checksum="F88933F0F0A38DCB" modified="2022-10-12" version="1">MDETGMKGGQGGSQAREGGPPRLRSCAATSRARPPARSLAAPSPTTSTRMRLDTVRTRSPSRPSRPHLPLRVASRLAICRSLCRENAYAWGWCGLVDGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM66</accession>
    <name>A0A8T0GM66_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G093800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315:SF89">
        <property type="entry name" value="OS01G0104100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15315">
        <property type="entry name" value="RING FINGER PROTEIN 41, 151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="142"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="12"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0559289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="48419" checksum="960C1A337E2D461D" modified="2022-10-12" version="1">MACPFAKLSINGGEKKCPVAKSEDKPGEAMIAGEQIESKKEGETTGAGRCPFGFDRKKPTEEVDEPKVDAQCEEEKGENAEAPVSGQCPFGYGKDKESKENNENGSEVQSEDREEETTMASAGGKCPLGYDSVSFKIGPFSCVLCRALLYDSSRCVPCRHIFCRGCISRFQDCPLCGLDIDGIESDSEMQGLVDRFIEGHARTIRPSLQTGAQEESAGNIKYEDISVERGSFLVQQAMRAFEGKNMESAKARLSLCVEDSREEMSRSGATSTSCSQLGALLGMLGDCCRAMQDIDGAIANYEESVDLLTKLPERDIEVVHALSVSLNKLGDLKYYAQELEAARAFYARALNVRLEATTDFTTLSSQVLDVAVSLAKVADVDFALGKESIATEGFQEALKKLENLKPPKSGEAAMLEKKVRCFYKYYIVHYTEPLNCVMKYCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP71</accession>
    <name>A0A8T0GP71_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phospholipase D</fullName>
            <ecNumber evidence="4">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G007700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phospholipase D family. C2-PLD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04015">
        <property type="entry name" value="C2_plant_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024632">
        <property type="entry name" value="PLipase_D_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF60">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12357">
        <property type="entry name" value="PLD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="C2" evidence="12">
        <location>
            <begin position="306"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="654"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="987"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="962"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0560723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1142" mass="127278" checksum="04CC254BD490F4AC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS86</accession>
    <name>A0A8T0GS86_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G131000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="23855" checksum="A940A9140274C102" modified="2022-10-12" version="1">MACTRRCTRTVKQTFEIHVSDREPGAVIETSERKKRLRFVLLGSPWFLKPFGMLLWSLLHLLLLVAGVSLIVLAAVPLLVLLALPLSWDVLWLPHCVFFACGLILWGIVDLIWSLMRLSWSLIREGERLHQIRAACRRFVEWWNFADLPFMSHRRHLMEMVSWNGLALTRKCVKRIGKWLGPWPVILLGRWCEEIVHVHDTIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTQ7</accession>
    <name>A0A8T0GTQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G072100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="8">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="23"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="82"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="17397" checksum="3871C3A1ECBE6831" modified="2022-10-12" version="1">MNQSSIDRGFFRSIFYRSYRDEEKKQGTLIKEEFERPNRENTTGMRHGSYDKLDDDGLAPSGTRVSGEDVIIGKTTPLPQDDNASQAQRYTKQDQSTCLRHSESGMIDQVLLTTNADGLRFVKIRVRSIRIPQIGDKFSSRHGQKGTVGMTYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV35</accession>
    <name>A0A8T0GV35_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G072300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="320"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="701"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="886"/>
            <end position="895"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1012" mass="114773" checksum="386BA11927A65C4D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW79</accession>
    <name>A0A8T0GW79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G076000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035900356" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="5695" checksum="B9D84FD298021FD2" modified="2022-10-12" version="1">MFGFGRCLVLAFRTGVGFSCFSRGDGDGDGCWGWEEVEAVRVIAFRVSGSGVSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWW6</accession>
    <name>A0A8T0GWW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_8G089400</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWW6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000162">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000108">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase S.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035824729" description="Protein kinase domain-containing protein" evidence="19">
        <location>
            <begin position="25"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="293"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="359"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="636"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="684"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0564176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="709" mass="78531" checksum="9695B3E0B39D0ACB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX63</accession>
    <name>A0A8T0GX63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G069500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007133">
        <property type="entry name" value="RNA_pol_II-assoc_Paf1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23188:SF12">
        <property type="entry name" value="RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03985">
        <property type="entry name" value="Paf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="532"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="26"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="600" mass="68002" checksum="E6C1DA2F8AA4D801" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYI5</accession>
    <name>A0A8T0GYI5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G083600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02205">
        <property type="entry name" value="CBS_pair_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00400">
        <property type="entry name" value="Voltage_gated_ClC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000051">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050368">
        <property type="entry name" value="ClC-type_chloride_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427:SF6">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9 12" id="KW-0868">Chloride</keyword>
    <keyword evidence="8" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="324"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="360"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="512"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="554"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="727"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="14">
        <location>
            <begin position="802"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="112"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0564110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="877" mass="92878" checksum="32A9FEC1E39CD59E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ51</accession>
    <name>A0A8T0GZ51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 19">Serine/threonine-protein kinase RIO1</fullName>
            <ecNumber evidence="4 19">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">KC19_8G164400</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 22">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 19">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4 19"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ51"/>
    <dbReference type="OrthoDB" id="205248at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05147">
        <property type="entry name" value="RIO1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000232">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000148">
        <property type="entry name" value="Serine/threonine-protein kinase RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051272">
        <property type="entry name" value="RIO-type_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018934">
        <property type="entry name" value="RIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018935">
        <property type="entry name" value="RIO_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017407">
        <property type="entry name" value="Ser/Thr_kinase_Rio1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45723">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01163">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038147">
        <property type="entry name" value="Ser/Thr_PK_RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01245">
        <property type="entry name" value="RIO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 19 21" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12 19" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 19 21" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="8 19" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 19" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO kinase" evidence="24">
        <location>
            <begin position="48"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="371"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="387"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="404"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="23">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="23">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="23">
        <location>
            <begin position="496"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="20">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="20">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRNR" id="PIRNR038147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR038147-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0565101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="533" mass="60430" checksum="0F7EFAC31BE6E106" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H015</accession>
    <name>A0A8T0H015_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G052900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H015"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007462">
        <property type="entry name" value="COV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876">
        <property type="entry name" value="COV-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31876:SF26">
        <property type="entry name" value="PROTEIN LIKE COV 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="11315" checksum="FD002391764B78F1" modified="2022-10-12" version="1">MLVDASGRNLLVLLFESGCIREYCWLSWFVVSAILLPIAVTFYITWWFIRFFDGFFSPIYESLGIHVIGNSQSGFCYAAVLLSDLSFYYKFSLLVRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0P6</accession>
    <name>A0A8T0H0P6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G105900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0P6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12753" checksum="B16C5412975559E2" modified="2022-10-12" version="1">MPNYEPLVNLVLFSIIVMACMCTAALIVMEKLYRFLINDIWPPDHQCEMSSLRWRDGEQEALEELGGLDETSNPSRSASRFMSVGFSDPAHHCKSIPCSYCGKDWPQLPSSNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6X6</accession>
    <name>A0A8T0H6X6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G070600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6X6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="582"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="403"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="447"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="479"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="694" mass="77012" checksum="9FE9D831141C2165" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H894</accession>
    <name>A0A8T0H894_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G095300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H894"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="16123" checksum="0AA28475F676E240" modified="2022-10-12" version="1">MRGRHMNDKIQSAMGSIHRAVRIGGHKVFRIVSICHWDMHLEAPWGQRTLPGRWSALNSEPAQKIHNHFSALKHRLPQRAELCTVYFFFAVEKSFVLQLWLQLWFHLWLQLWFYLWLQLGSCLQYVGLFHQDCTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8G5</accession>
    <name>A0A8T0H8G5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GTP-binding nuclear protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G078900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the small GTPase superfamily. Ran family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8G5"/>
    <dbReference type="OrthoDB" id="2012850at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000054">
        <property type="term" value="P:ribosomal subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00877">
        <property type="entry name" value="Ran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000369">
        <property type="entry name" value="GTP-binding nuclear protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002041">
        <property type="entry name" value="Ran_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071:SF0">
        <property type="entry name" value="GTP-BINDING NUCLEAR PROTEIN RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24071">
        <property type="entry name" value="RAN GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00627">
        <property type="entry name" value="GTPRANTC4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51418">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0566644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="223" mass="25293" checksum="9416114A80943FED" modified="2022-10-12" version="1">MALPGQTTPDNCPSFKLVIVGDGGTGKTTFVKRHLTGEFEKKYEPTIGVEVHPLDFFTNCGRIRFYCWDTAGQEKFGGLRDGYYIHGQCAIIMFDVTARLTYKNVPTWHRDLCRVCENIPIVLCGNKVDVKNRQVKAKQVTFHRKKNLQYYEISAKSNYNFEKPYLYLARKLAGDVNLHFVESPALAPPEVQIDLAAQAQYEAELKAAQSMPLPDDDEDTFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8V2</accession>
    <name>A0A8T0H8V2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G081000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8V2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="9273" checksum="92126C4C95B8B483" modified="2022-10-12" version="1">MGDMSKAGTDKTSLEERQRVEKKMREAKHEEFTPRWFKTLHPHFGAIWKYPNIMASTMSTARRYRLKQLASWKTWKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA06</accession>
    <name>A0A8T0HA06_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G039900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA06"/>
    <dbReference type="OrthoDB" id="1879366at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009809">
        <property type="term" value="P:lignin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05283">
        <property type="entry name" value="CAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000022">
        <property type="entry name" value="Cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.180.10:FF:000004">
        <property type="entry name" value="probable cinnamyl alcohol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047109">
        <property type="entry name" value="CAD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42683">
        <property type="entry name" value="ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="6">
        <location>
            <begin position="24"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0568706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="359" mass="38855" checksum="A1D4D61B08D0C238" modified="2022-10-12" version="1">MSRMGSDAHVPIEVFGYAAKDTTGHMSPFKFTRKPAGAEDVTLKVHYCGICHSDLHQLRGDWGNSKYPMVPGHEIVGTVTSVGSAVSKFKVGDTVGVGCMVYSCHNCDSCDKGLEQYCDKMVWTYNDVLPDGTATQGGYSTIMVANEKFVVHIPENLPKDAAAPLLCAGITIWSPMLYFGMNVKGAKFGVVGLGGLGHMAVKFGKAFGMHVTVFSTSPSKEKEARELLGADDFVVSRDEEAMNAKAKSLDFIINTISVQHSLNPYLSTLKSNGKMCLVGIPEKELSVLPVQLVAGRKMVAGSLIGGMKETEEMLEFCGKNNITCLVETLPVAECNTAMERLANNDVKYRFVLDLDSVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAR2</accession>
    <name>A0A8T0HAR2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G045500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAR2"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000004">
        <property type="entry name" value="Small nuclear ribonucleoprotein-associated proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="250"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0566202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="31439" checksum="CF4CA48AE687CA29" modified="2022-10-12" version="1">MAMSKTSKMLLYINWRMRVTIQDGRQLVGKFMAFDRHMNLVLGDCEELRRVPPKKGKSQEEREERRTLGLLLLRGEEVISMTVEGPPPPDESRAKAAAAAAGGPGIGRAAGRGIPTAPANQAQPGLAGPARGVGGPAPGMMQPRPQVSAGPVTYTPPPGPIPGVRPPGPPPPGQYAPRPMPGPPGAPPPGMRPPQMMQGPPGQGPPQGYGQGPPGRPMPPPPGPPPQMSGPGMPGPYGQRPMGPPQMMRGPPPGMGGPGGPPRPGMPPQMQGPPRPGMPPPPGAPPGMYGGPRPGMPPPQQQPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE93</accession>
    <name>A0A8T0HE93_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G137100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE93"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11542" checksum="6E39C23BB85B27EB" modified="2022-10-12" version="1">MQRAMNDDDDGLERCGILGSEGRASGECGGWRGIRRRGAFPQVWRGEQWGSFQRCRCRRLSAAVDCTDAHKPTQQCSPFLFFCFPFQGTFPRFNSARLQPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFJ6</accession>
    <name>A0A8T0HFJ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G087800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12949" checksum="B7BDD0529CDB8EC4" modified="2022-10-12" version="1">MQCTGIVGEARRSVIMLLVRGYILRLLRACSLEVELWRRILLKGSDYLELYQSGCYNQLIGLESFSQWPRLSESLRKFLSRRFEINVCAFLYRILSILYTKYQVRCGGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG75</accession>
    <name>A0A8T0HG75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">CP-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G129400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051239">
        <property type="term" value="P:regulation of multicellular organismal process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd04178">
        <property type="entry name" value="Nucleostemin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1580.10:FF:000002">
        <property type="entry name" value="Guanine nucleotide-binding protein-like 3 (nucleolar)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000571">
        <property type="entry name" value="Guanine nucleotide-binding protein-like NSN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050755">
        <property type="entry name" value="TRAFAC_YlqF/YawG_RiboMat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089">
        <property type="entry name" value="GTP-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11089:SF30">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CP-type G" evidence="7">
        <location>
            <begin position="180"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="511"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="579"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="519"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="596"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="614"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="636" mass="71115" checksum="7D909AF2ED7BA54B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHT1</accession>
    <name>A0A8T0HHT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Choline kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G155000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the choline/ethanolamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004103">
        <property type="term" value="F:choline kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004305">
        <property type="term" value="F:ethanolamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05157">
        <property type="entry name" value="ETNK_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603">
        <property type="entry name" value="CHOLINE/ETHANOALAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22603:SF93">
        <property type="entry name" value="RE24176P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01633">
        <property type="entry name" value="Choline_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="45380" checksum="BA1578879447D70B" modified="2022-10-12" version="1">MGVVEEAMEAAERPRHEDSGGLAALMGSTQGSVEVEGGGGIYSQGSIELPVEAYKQLRKLAGKWADIVDPVDLKLTRLKGAMTNNVYQCHWKRNDGNRDKKVLVRVYGEGSGLFFDRNDEVLTFERMSLKGQGPRLMGRFPNGRVEEFLRARTLEQHDIRDPEISKKIAVKLRDFHSLDMPVKTGGRKAKIWERLREWLMKIQDHSDSSQVSDGGLSKLDDEIIDPNYLEDEINYLQQRLDKRDTQIGFCHNDLQYGNIMLSEKDDSVTLIDYEYASYNPVAFDIANHFCEMTADYHSDEPHVLHPELFPRDEEQDRFLRAYLEASGDAVSQADVDKLREEVKEFVLASHLHWVLWGLLSAKYQDVEFDFVGYSKQRLSLYKELKHQSESQTKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJC2</accession>
    <name>A0A8T0HJC2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G195200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="19013" checksum="6199882C8BF31D00" modified="2022-10-12" version="1">MFELGALLGVELKKKLTWQGVRQSEVEFYLWSQQSIFPYVQLITDMEHGGVAIYCRSGRDVRILTLESMEGVRQFLKEFGNSLPPDLGQDDLTSGRLVCPDSLSGPARKKFKSSDFGVNSTSQQQDTSQTAGQVALWSMAARWKNNLHDVGNMRDFDDFGDFGDDALVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJN0</accession>
    <name>A0A8T0HJN0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Multiple myeloma tumor-associated protein 2-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G203900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019315">
        <property type="entry name" value="MMTA2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039207">
        <property type="entry name" value="MMTAG2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580:SF0">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14580">
        <property type="entry name" value="MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10159">
        <property type="entry name" value="MMtag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Multiple myeloma tumor-associated protein 2-like N-terminal" evidence="3">
        <location>
            <begin position="95"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="178"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="143"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="59"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="255"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="271"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="348"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="413"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="448"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="559" mass="65365" checksum="84212D3EE8564522" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMB5</accession>
    <name>A0A8T0HMB5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">uroporphyrinogen-III C-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.107</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG057500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.107" evidence="1"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004851">
        <property type="term" value="F:uroporphyrin-III C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019354">
        <property type="term" value="P:siroheme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11642">
        <property type="entry name" value="SUMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.950.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1010.10:FF:000001">
        <property type="entry name" value="Siroheme synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="entry name" value="Cobalt-precorrin-4 Transmethylase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="entry name" value="Methyltransferase, Cobalt-precorrin-4 Transmethylase, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006366">
        <property type="entry name" value="CobA/CysG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050161">
        <property type="entry name" value="Siro_Cobalamin_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003043">
        <property type="entry name" value="Uropor_MeTrfase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01469">
        <property type="entry name" value="cobA_cysG_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004790">
        <property type="entry name" value="PRK06136.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790:SF3">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45790">
        <property type="entry name" value="SIROHEME SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="Tetrapyrrole methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00839">
        <property type="entry name" value="SUMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tetrapyrrole methylase" evidence="7">
        <location>
            <begin position="153"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="403"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0571969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="444" mass="47338" checksum="C86D5029B188D0F3" modified="2022-10-12" version="1">MAALCQRVSWHHVSSQFVPVRRDGAGWSGAGKSLGGWGVRARREQESPFTEKASVKMRGGGHGSGVALKSLELWDAGRAREAQPGVSSDGLQSLTGASAEFRESKDESSGPGYEDDDIAARLPELREVLSLLCTQWAQEEASGSQRKRGPGNVFLVGTGPGNPDLLTVKALKLMQSAELVLYDRLVSTDILDLVHDGARLLYVGKTSGYHSRTQEEIHELLSSFAESGATVVRLKGRDPLVFGRGGEEMDFLQEQGINVQVVPGITAASGIAAELGIPLTHRGAANSVRFLTGHSRKGGDDPLYVAERAADPDSTLVIYMGLATLPGLAAKLMANGLPSDIPAVAVERGTTAQQRVVFAHLNDLPAEVAGAKLESPTLIIIGRVVALSHLWPFKTIAVAGEAEDQSAQLEATATSVKAEKPEDMKREPRVRSLRGPDPILPRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPL3</accession>
    <name>A0A8T0HPL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tubulin beta chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_VG128100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02187">
        <property type="entry name" value="beta_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000002">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000005">
        <property type="entry name" value="Tubulin beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013838">
        <property type="entry name" value="Beta-tubulin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002453">
        <property type="entry name" value="Beta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01163">
        <property type="entry name" value="BETATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00228">
        <property type="entry name" value="TUBULIN_B_AUTOREG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="13">
        <location>
            <begin position="47"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="14">
        <location>
            <begin position="246"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0572822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="49706" checksum="F53292F844AE2DF5" modified="2022-10-12" version="1">MREILHIQAGQCGNQIGAKFWEVICDEHGIDPTGTYHGDSDLQLERINVYYNEASGGRYVPRAVLMDLEPGTMDSVRSGPFGQIFRPDNFVFGQTGAGNNWAKGHYTEGAELIDSVLDVVRKEAESCDCLQGFQVCHSLGGGTGSGMGTLLISKIREEYPDRMMLTFSVFPSPKVSDTVVEPYNATLSVHQLVENADQCMVLDNEALYDICFRTLKLTTPTFGDLNHLISATMSGVTCCLRFPGQLNSDLRKLAVNLIPFPRLHFFMVGFAPLTSRGSQQYRSLTVPELTQQMWDAKNMMCAADPRHGRYLTASAMFRGRMSTKEVDEQMLNVQNKNSSYFVEWIPNNVKSSVCDIPPKGLKMASTFIGNSTSIQEMFKRVSEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDASAEDEGEYDIEEDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPS8</accession>
    <name>A0A8T0HPS8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG125200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9978" checksum="CA9C8967080EC104" modified="2022-10-12" version="1">MVGAKSSTTLDENVTHIVTFHKEGQELPRDWVLRSLGGEKEQELVLYGHFCHPHGQYINVVYQDWLADSLAKGFILCEMKFMAVPRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQV5</accession>
    <name>A0A8T0HQV5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_VG167000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18008">
        <property type="entry name" value="DEXDc_SHPRH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16449">
        <property type="entry name" value="RING-HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056450">
        <property type="entry name" value="UBA_RAD5A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF22">
        <property type="entry name" value="DNA REPAIR PROTEIN RAD5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24559">
        <property type="entry name" value="UBA_RAD5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="16">
        <location>
            <begin position="632"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="1007"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="17">
        <location>
            <begin position="1077"/>
            <end position="1240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="72"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="665"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="94"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="133"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="669"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0573304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1242" mass="135943" checksum="0C7C539F802E7EFB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTR7</accession>
    <name>A0A8T0HTR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG236000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1740.20:FF:000002">
        <property type="entry name" value="40S ribosomal protein S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="entry name" value="Ribosomal protein S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_eS26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047864">
        <property type="entry name" value="Ribosomal_eS26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_eS26_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00733">
        <property type="entry name" value="RIBOSOMAL_S26E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0574125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="13964" checksum="9C6A76FA01AF4994" modified="2022-10-12" version="1">MTVKRRSGGRNKHGRGHVSPIRCSNCGRCVPKDKAVKRFLVRNIVEQAAVRDVQEACVYDGYVLPKLYAKMQYCISCAIHSHVVRVRSHEARRIRDPPQRFRRKEDGPASTVPGARLAANQAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXT5</accession>
    <name>A0A8T0HXT5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G015300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071254">
        <property type="term" value="C:cytoplasmic U snRNP body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016604">
        <property type="term" value="C:nuclear body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071208">
        <property type="term" value="F:histone pre-mRNA DCP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071209">
        <property type="term" value="F:U7 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052840">
        <property type="entry name" value="U7_snRNA_Sm-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21196">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21196:SF1">
        <property type="entry name" value="U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="11744" checksum="7AD69A0592E5AE48" modified="2022-10-12" version="1" fragment="single">ICNLKALVGLELLVELRNDLSVRGVLHDCDNASNVIIKDATVEDVEGVQRQLPLVFLRGSNIRFVHIPDNVDVMQLVEDRRLMLDKAATAYMGGKGAPAPKPVPGAGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYK9</accession>
    <name>A0A8T0HYK9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G030300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYK9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015245">
        <property type="term" value="F:fatty acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1740">
        <property type="entry name" value="Transmembrane protein 14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005349">
        <property type="entry name" value="TMEM14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044890">
        <property type="entry name" value="TMEM14_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668:SF5">
        <property type="entry name" value="PROTEIN FATTY ACID EXPORT 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 14, 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03647">
        <property type="entry name" value="Tmemb_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0575779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="12679" checksum="AC18D3CCD4D153A6" modified="2022-10-12" version="1">MHDFCFTYPYGLLVVLGGLIGFLKKGSADSLMGGVGSGALLLLAGYVSHQAYLRGAKSWPALFLETVVAVALTWVMGQRFMATSKFMPAGLVAALSGIMALFYLYKVVTGGNHIVKKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ97</accession>
    <name>A0A8T0HZ97_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G083700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd06472">
        <property type="entry name" value="ACD_ScHsp26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.790:FF:000053">
        <property type="entry name" value="17.5 kDa class I heat shock protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="56"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="19290" checksum="4A610FD13FCB8532" modified="2022-10-12" version="1">MAMTPHHHNKEHGGHDKQLQNKEQSLSVFDPFSWDPFENFGALWNNSEAGKSFANDMRAVACTKVDWKETADSHVFKADLPGLTKEEVKVTVEDGNTLQITGERMKEGVDKNDKWHRVERSQSKFLRRFRLPENTNIDAVKAKVSHGVLTVTVPKKTSSKNSTPRYIDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZR8</accession>
    <name>A0A8T0HZR8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G097500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035787710" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7621" checksum="9B094B71B2D51B61" modified="2022-10-12" version="1">MLRSCHSLKTLFFSCLKVTDTFEGCTCRRCGQTGSLRELGVHGITKMRSGHQRSCTRWRITTGVRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0I6</accession>
    <name>A0A8T0I0I6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G121300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058942">
        <property type="entry name" value="AT3G52170-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058941">
        <property type="entry name" value="HTH_AT3G52170-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34568:SF5">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34568">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25896">
        <property type="entry name" value="HTH_AT3G52170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="344"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="136"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="417"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="684" mass="75600" checksum="86953D3F0B49BD6B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3W0</accession>
    <name>A0A8T0I3W0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G180800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3W0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="16178" checksum="067631E2AAABEE16" modified="2022-10-12" version="1">MWFPLPHCWNCLQCECHSRSGCGPRFRILAISFFRVSARQFLIVLSIFQDLLGFPSSLARVFFCFRFRYSNGHEDSLVGAIGLSGSLCRCPWNGSGGCLLLVMKMIFLVWLDFLCRIRTAFVILMTIWPASSFITTLGMTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4H1</accession>
    <name>A0A8T0I4H1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G020200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4H1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="34069" checksum="B88672F03FFC7411" modified="2022-10-12" version="1">MQELIAMIKRSASESRHPRGHTADAIETHQSSPHKPESPTASMKTVLLSPASAVTETINKAKENVETRVSSGNSRSPNSNETTFEANTPRLPMPSDETAKANGDAVVAAVTLPVDDLSTAAPSDNDPPIDVAACGYHTRPDPILTPMETPREMMDILLPQASDWDNDFEPLPPRRIQQTTVVPVETRGRKKGKTTSMCTKVPPEPILPRDEGCDPISVGKPVWILHEQFPLIVVAQGKAGVAWRTKSNKLGAQCSEGHQWIHVHRIFKHSVPLLFPEPKVGCSVLESALPPAQGRHKQIMWSSRHLITYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4X8</accession>
    <name>A0A8T0I4X8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G001400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4X8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16097" checksum="BFB37137D4DE55BE" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSLKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I508</accession>
    <name>A0A8T0I508_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 4 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">26S proteasome regulatory subunit RPN10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G169100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I508"/>
    <dbReference type="OrthoDB" id="1731724at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01452">
        <property type="entry name" value="VWA_26S_proteasome_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3990:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit N10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="5"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="246"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="246"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="412" mass="42290" checksum="8A03C94DBC8CEE39" modified="2022-10-12" version="1">MVLEATMVCMDNSEWMRNGDYTPTRFQAQADAINLICGAKTQSNPENTVGVLTMAGKGPRVLITPTNDLGKILQALHGLEVGGEMSMTSGVQVAQLALKHRQNKHQRQRIVLFAGSPVLAEKKTLEGMGKKLKKNNVALDIVSFGEDDGEKVEKLEALLNAVNSNDNSHIVHIPGGDRVLSDVLISSSIFTGDGEGGSGFAAAAAASAAAAAVGGGGGGAYDFGVDPNLDPELALALRVSMEEERARQEAAMKRSAEDSTAKGQAAGESSSAPDVAMSDAGPVEITDKTSDMMIDDDSALLEQALAMSMAEAAAAAAGAGPAADISMAESGGDDQDLAYALQMSMQEAAAAASAAQGSADVNQVLGDQSFVSSVLSSLPGVDPNDPSVQDVLASLQAEEEKNEDQAAKGPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I610</accession>
    <name>A0A8T0I610_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Agenet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G023200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I610"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014002">
        <property type="entry name" value="Agenet_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055274">
        <property type="entry name" value="SWO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429:SF1">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00743">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="554"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="650"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="517"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="711"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="463"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="775"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="903" mass="99661" checksum="E5555BFCECC52955" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9A3</accession>
    <name>A0A8T0I9A3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G160400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9A3"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045096">
        <property type="entry name" value="EDR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136:SF47">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE PROTEIN (DUF1336)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START" evidence="2">
        <location>
            <begin position="289"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="843" mass="94374" checksum="1F070C5C787EAB3D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAP3</accession>
    <name>A0A8T0IAP3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 17">Peroxidase</fullName>
            <ecNumber evidence="3 17">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_4G142400</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="14 17">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="14 17">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="3 17"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31235">
        <property type="entry name" value="PEROXIDASE 25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 14 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 17" id="KW-0349">Heme</keyword>
    <keyword evidence="17" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 14 17" id="KW-0408">Iron</keyword>
    <keyword evidence="18" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 17" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0964">Secreted</keyword>
    <keyword evidence="18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="19">
        <location>
            <begin position="79"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="15">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="89"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="180"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="261"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0580029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="389" mass="42934" checksum="FF4BFAD2533DC2E5" modified="2022-10-12" version="1">MYFHQKTRTRTILYECLRQEYSTIASRRHPCSSQIHQLQHHIRKFIPKTMDKVMALILSMLMAFLNLALHVNAVPPGSALSSTYYDGLCPGGTKRFQTIASTIVAAKVIADPTLIPALARMCFHDGWVEGSDASVLLDFNSSFPDVEKNSPANNPSLRGYEVIDAVKSAVEAYCPGVISCADILQESVRVAFKTLFAGSLLYNIRYGRRDGSISLITEANQQLPPPTFNYSQLITSFASKGFNAHELMVLSGAHTFGVSHCSSFTSRLYNFYGNGTGTDPALDPTYAFALKVACPQTATVDGIVPLDYAKPIITLPSFDNQYYKNILAGKVLFISDNALQVGDLAEVNLYASNNNQFRNDFAQAIVKLSEVQVKLYPNGQIRANCRKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAU6</accession>
    <name>A0A8T0IAU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G148800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11608" checksum="55D8D6E7EABC4E0F" modified="2022-10-12" version="1">MLAKPHSPPRSTFPESSPPLTALHPIATTSTSSLIHSPDLKRPAHAETEKKLTRTEPRSRGAPPKLRELAIDRSRHTTSHDHPHLSVTRLRAHLKRRKQQTAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB97</accession>
    <name>A0A8T0IB97_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G192800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="3">
        <location>
            <begin position="115"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="310" mass="35481" checksum="E6B9ACCFE611928D" modified="2022-10-12" version="1">MRITRAAGTRRSPSRGRRGRLASRSRSKSRSRAKLKNTAISADDLPSCNRRGWVDRIVDYDTNFSYWIHEQGLQFFFYMVLRILEFSGEGLFLIPAAAAAYLLPKGKLNPEVRMFFFNLLGAFIVDLVIVTLIKNYVRRRGPMYCHVHHVTGEDRSFPSGHSTRALMVVTFFTMYLPMWRVQAANVWLPFLKRVLSNEVRILDEGVPMLESFLVSVVTWLVFSWAVATTSSRIILGRHFFFDVLVGCLVGTLESILYNNFLVIPHAVLFLLEVVLEWVRSGLNLVYRTWLGWQGRYLMAALIVAAGFATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBN5</accession>
    <name>A0A8T0IBN5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2 6">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G164800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = trans-zeatin + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2 6"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBN5"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0580326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="240" mass="25831" checksum="8D7FC1F4CE930465" modified="2022-10-12" version="1">MGAKVELKQEVPVVVVPDTEKMMFPSKRFKKICVFCGSSSGKKGVFSNEALNLGRELVNRKIDLVYGGGSIGLMGQVAHTVKSGGGHVVGVIPKALIGKELTGSTVGELIAVTDMHQRKAEMARQADAFIALPGGYGTLEELVEVITWNQLGIHKKPVGLLNVDGFYDTLLTFFDKQLEEEFFDNSARSIVVSAPTASELLDKLEAYTPTLAYGPKLCWDQVDRPCGLGFTATPIAGLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGA8</accession>
    <name>A0A8T0IGA8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Carboxypeptidase</fullName>
            <ecNumber evidence="5">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G258200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGA8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11320:FF:000002">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12670:FF:000002">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000211">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF470">
        <property type="entry name" value="CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035965992" description="Carboxypeptidase" evidence="5">
        <location>
            <begin position="23"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="467" mass="52045" checksum="99D6519648F64FA7" modified="2022-10-12" version="1">MSKLIQFLVVYFLLVGYLLGDAQSQAATADLDRVLALPGQPPVGFKLYAGNVTVNAEQGRDLFYVFAQCSNDVSGTKPLVLWFNGGPGCSSIASGFSQENGPFRILPGGAGLTVNEYAWNTEVNMIWLESPTGVGFSYSRLNMADNTGGGDARTAEDAYNFLVGWLDRFPQYHGRDFYITGESYAGHYVPQLAKKILERNAVSPLKINLKGYMVGNPDIDNYWDYTGDIDYYHSHAMISTETYQGLKKNCNFLEGDCCSLLCNDFFTKMYSEMGNIDPYSIYTDVCVHSNANKMQSMWTRKNPMMLRRGMRAGYDPCSEDKAEIYFNRPDVQHALHANTSGVIPYAWTQCSEILHNNWTDAPLSMISIYHELIASGLKIWVYSGDADSVVPVTSTRYSIEAMNLPIVKPWHPWYDHQQVGGRVVVYNGLTFVTIRGAGHQVPLLQPGRFLQLLKSFIAGENLPGSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGK4</accession>
    <name>A0A8T0IGK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_11G086100</name>
        <name evidence="17" type="ORF">KC19_3G023500</name>
        <name evidence="18" type="ORF">KC19_3G029000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18 19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGK4"/>
    <dbReference type="OrthoDB" id="2356065at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000039">
        <property type="entry name" value="receptor-like protein kinase FERONIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052422">
        <property type="entry name" value="Auxin_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986:SF1">
        <property type="entry name" value="OS04G0685900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986">
        <property type="entry name" value="OSJNBA0070M12.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0556880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0581961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0582041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16509" checksum="4DBAC9437AFFAD40" modified="2022-10-12" version="1">MVLDFNHAGTGVMVHSIHQLRSVTDNFAESNVLGQGGFRVVYKGVLADGTKIDVKRIQLAVVSSKGLSELRSDIAILTKVKHRHLVALLGYCTDGIERLLVYEYMSQGPLAQHLFKYEEMTGKPLSWTMRLEKCAWTLSKRWSICTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGT6</accession>
    <name>A0A8T0IGT6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G097300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07831">
        <property type="entry name" value="STKc_MOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000271">
        <property type="entry name" value="MAPK/MAK/MRK overlapping kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000773">
        <property type="entry name" value="MOK protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="4"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="299"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="441"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="332"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="441"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0582950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="574" mass="65151" checksum="0F1E55DFA6F2024F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH09</accession>
    <name>A0A8T0IH09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nuclear segregation protein Bfr1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G034700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042175">
        <property type="term" value="C:nuclear outer membrane-endoplasmic reticulum membrane network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008298">
        <property type="term" value="P:intracellular mRNA localization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039604">
        <property type="entry name" value="Bfr1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027:SF2">
        <property type="entry name" value="LEBERCILIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31027">
        <property type="entry name" value="NUCLEAR SEGREGATION PROTEIN BFR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="369"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="434"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="240"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="465"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="491"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58823" checksum="8DAF1F0C9037D0EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHC0</accession>
    <name>A0A8T0IHC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G048800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028131">
        <property type="entry name" value="VASH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750:SF2">
        <property type="entry name" value="VASOHIBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750">
        <property type="entry name" value="VASOHIBIN-1-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14223">
        <property type="entry name" value="Retrotran_gag_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14822">
        <property type="entry name" value="Vasohibin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="632"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="673"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="278"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="727"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="759"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR628131-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="777" mass="87643" checksum="FE275E1CD69D3C41" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHL3</accession>
    <name>A0A8T0IHL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G054700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHL3"/>
    <dbReference type="OrthoDB" id="1924287at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.180:FF:000004">
        <property type="entry name" value="pre-mRNA-splicing factor CWC22 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF3">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="7">
        <location>
            <begin position="461"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="415"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="670"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="416"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="688"/>
            <end position="697"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="721" mass="82214" checksum="279E6F3B3DEBC82A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHN8</accession>
    <name>A0A8T0IHN8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G024700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="285" mass="31939" checksum="C0CC10E56D28E338" modified="2022-10-12" version="1">MGSTPGAGGQAIPDTVFADIESELVEYDERECLLANAYREEEQRRREREEEDRSRDRERAQTQAGGVNLASFPNGLGVGGVDSDEEAAGELSYCYNEIKNLVLIEKSLIHKKALEEWTRKENLFTARVERKTKKVDSLKNEVYQLLGFFSVFQGVLLTAVSQSNLLHCNNLWSPIVLSVLASIVTIAAIAQKLYQISSLLGTISSEEQAVKDVVHRGQELRREGKNFVFAKFSKNKQKEPKKNYFRLYAVLVLSFLVLFTVAFALSHWRILCYPGSTGSPASPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ30</accession>
    <name>A0A8T0IJ30_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Cation/H+ exchanger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G103800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ30"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1530.20:FF:000003">
        <property type="entry name" value="Cation/H(+) antiporter 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057291">
        <property type="entry name" value="CHX17_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057290">
        <property type="entry name" value="CHX17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050794">
        <property type="entry name" value="CPA2_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468">
        <property type="entry name" value="CATION/H + ANTIPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32468:SF0">
        <property type="entry name" value="K(+)_H(+) ANTIPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23256">
        <property type="entry name" value="CHX17_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23259">
        <property type="entry name" value="CHX17_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="264"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="406"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="13">
        <location>
            <begin position="43"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H(+) antiporter central" evidence="14">
        <location>
            <begin position="479"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H(+) antiporter C-terminal" evidence="15">
        <location>
            <begin position="624"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="820"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="870"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF23256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF23259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0583035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="879" mass="95196" checksum="145448C05946A392" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJQ0</accession>
    <name>A0A8T0IJQ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G111900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1065" mass="120724" checksum="A9929312FD58AB94" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJX0</accession>
    <name>A0A8T0IJX0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G037600</name>
        <name evidence="3" type="ORF">KC19_3G183800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274548" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5680" checksum="7D947B17D0F75EEC" modified="2022-10-12" version="1">MVLWHIAAVLKLLLWNDYIMLIMESRALVWCCSNDVAQGKCVVKPCARSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKU3</accession>
    <name>A0A8T0IKU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Polygalacturonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G151500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31375">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="127"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="584" mass="63682" checksum="3B1888550B7C9E3A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL47</accession>
    <name>A0A8T0IL47_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G148900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044282">
        <property type="entry name" value="ABAP1/ARIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46710">
        <property type="entry name" value="ARM REPEAT PROTEIN INTERACTING WITH ABF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46710:SF1">
        <property type="entry name" value="ARM REPEAT PROTEIN INTERACTING WITH ABF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7089" checksum="B9B8703B2C0CF674" modified="2022-10-12" version="1">MMRFIYTGNVEVATDNAQDLLRAADQYLLEGLKRLCEYSIAQVCVAEVTTTAAKFCHCQFPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMA3</accession>
    <name>A0A8T0IMA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Xanthine dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_3G155100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="16">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="16">Binds 2 [2Fe-2S] clusters.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the xanthine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000003">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1170.50:FF:000001">
        <property type="entry name" value="Aldehyde oxidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.365.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.50:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.30:FF:000012">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.43.10:FF:000001">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.465.10:FF:000004">
        <property type="entry name" value="Xanthine dehydrogenase/oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.120">
        <property type="entry name" value="[2Fe-2S]-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.50">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.365.10">
        <property type="entry name" value="Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.50">
        <property type="entry name" value="CO dehydrogenase flavoprotein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046867">
        <property type="entry name" value="AldOxase/xan_DH_MoCoBD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45444:SF3">
        <property type="entry name" value="XANTHINE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="MoCoBD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20256">
        <property type="entry name" value="MoCoBD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000127">
        <property type="entry name" value="Xanthine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
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        </ligand>
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        <location>
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        </ligand>
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        <location>
            <position position="829"/>
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        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
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            <name>Mo</name>
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            <name>Mo</name>
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    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
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        </source>
    </evidence>
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        <source>
            <dbReference type="PIRSR" id="PIRSR000127-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0583688.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1403" mass="153471" checksum="E8F56BE6AC2449F2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INC7</accession>
    <name>A0A8T0INC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anticodon-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G271500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451:SF46">
        <property type="entry name" value="THREONINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="THREONINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anticodon-binding" evidence="2">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12351" checksum="69DA7C0C57EB65CD" modified="2022-10-12" version="1">MFAILLEHYAGKWPFWLSPRQCIVCPVSEKFTQYAIEVRDAINAAGYYCEADVSDRKLQKKIREAQLAQFNYILVVGEDETTKKQVSLYLFSADFFYFIMIYKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP86</accession>
    <name>A0A8T0IP86_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G021200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP86"/>
    <dbReference type="OrthoDB" id="998115at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31152:SF23">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="196" mass="22131" checksum="04E62DB0B4AF4703" modified="2022-10-12" version="1">MANSKNMQVYEARKHLPNMWHSDLLRTPVEAPAYCCYAMWCPCLVAYQQRGRVLYDDWSRYQCCGGGMPCSGSCGESKCPQLCAVVEVTLCFTLAVSATRFMLQDALQIQNTKCDNCIIASMFFAQYLNCLCWIAAMVTSIPFIDEAAVITDRIADISYCTVCACIQTQHKLELDKRDGKIQPRETIPPPQQHMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPQ7</accession>
    <name>A0A8T0IPQ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G248900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="20144" checksum="8FBB3CDC518FE990" modified="2022-10-12" version="1">MFDMYDKITDRGGEFDYMCFNPFMTSSTGPSGLQPVPQVSNLRTDWALYVHSLSEFNRPLNSQQQQRLCGFPGLQHPQNSGYGEAIRRTHLGCIVNHRFTFMVQENREAVNLSRTKRSGNNVLIHTKYANLLRFGRRIQKAFCTLLVFCRDSEFRPKNLYTWEMHFPGCYTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPT2</accession>
    <name>A0A8T0IPT2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Conserved oligomeric Golgi complex subunit 7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Component of oligomeric Golgi complex 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G236100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPT2"/>
    <dbReference type="OrthoDB" id="245173at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017119">
        <property type="term" value="C:Golgi transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019335">
        <property type="entry name" value="COG7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21443:SF0">
        <property type="entry name" value="CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10191">
        <property type="entry name" value="COG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0584811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="852" mass="93099" checksum="DC44D9D411D90DA3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ59</accession>
    <name>A0A8T0IQ59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G231500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ59"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="392"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="41"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0584748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="462" mass="50428" checksum="6D5B73320CF1CEE7" modified="2022-10-12" version="1">MNGHVSYSVLQPASEEEGNTQPAQNALKDVDGGALFVLESKGNWQHAGFHLTTSIATPAMLTLPFALRELGWFAGILALTLCAGVSFYAYTIISQVLEHSERRGHRFLRFRDLGAYILGPWGYYTIGAIQIVVCLGCVIGSCIIGGQSMKLIYGIYDPDCTRPLSEYIGFFGVIMLLLAQLPSFHSLRYINLASLIFCLGFALCVVGGCIYAGSSSQAPPKDYSVPGTPVSKLFGVFESLAIITTAFGNGIIPEIQATLAPPVANKMFKGLLVCYAVVMSTFFSVAISGYWAFGNQAAGYVLTNLAPKDGPALVPSWLIVLANTFILAQLIAVALVYSQPTFEIFEGRSSDVKQGKYSMRNLVPRFILRSSYVVFATFVSAALPFFGDINGVLGAFCFTPLDFVLPFLFYSATFGPSRHTSRFWIHWGIIVLFTLIGFLGCISSIRQIVLDAKYFKWFADLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQY4</accession>
    <name>A0A8T0IQY4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,3-beta-glucan synthase</fullName>
            <ecNumber evidence="3">2.4.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">1,3-beta-glucan synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G267500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>[(1-&gt;3)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1-&gt;3)-beta-D-glucosyl](n+1) + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21476"/>
            <dbReference type="Rhea" id="RHEA-COMP:11146"/>
            <dbReference type="Rhea" id="RHEA-COMP:14303"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37671"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.4.1.34"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.34" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1880850at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058851">
        <property type="entry name" value="CALS1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026899">
        <property type="entry name" value="FKS1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF7">
        <property type="entry name" value="CALLOSE SYNTHASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25968">
        <property type="entry name" value="CALS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14288">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01205">
        <property type="entry name" value="FKS1_dom1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="383"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1334"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1480"/>
            <end position="1499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1505"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1610"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1643"/>
            <end position="1665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1671"/>
            <end position="1695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="1715"/>
            <end position="1734"/>
        </location>
    </feature>
    <feature type="domain" description="1,3-beta-glucan synthase component FKS1-like" evidence="15">
        <location>
            <begin position="147"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00047777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0585211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1769" mass="205776" checksum="3C5BF5A348865CEF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR90</accession>
    <name>A0A8T0IR90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G019700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR90"/>
    <dbReference type="OrthoDB" id="10481507at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17476" checksum="791569B8F7929348" modified="2022-10-12" version="1">MKLSPEECVEVVQSTGQHMSPPALARTKSSMGSIVVDMGNRGEVEVRGMDMYSPCKKSARPEPASRIHLIPLLMIFVFFVLWAGSTEVPLNEDLKPEVFAMKLPTTNGLATSGQVVADEISQRGTETALDQDHPTHHQVDSHALSTNGLSEKTYVRGTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRM1</accession>
    <name>A0A8T0IRM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_2G013800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>XMP + L-glutamine + ATP + H2O = GMP + L-glutamate + AMP + diphosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRM1"/>
    <dbReference type="OrthoDB" id="1724632at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003921">
        <property type="term" value="F:GMP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000002">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000001">
        <property type="entry name" value="GMP synthase [glutamine-hydrolyzing]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000848">
        <property type="entry name" value="PRK00074.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922:SF2">
        <property type="entry name" value="GMP SYNTHASE [GLUTAMINE-HYDROLYZING]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11922">
        <property type="entry name" value="GMP SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03054">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54810">
        <property type="entry name" value="GMP synthetase C-terminal dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="15">
        <location>
            <begin position="208"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="236"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0585466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="535" mass="58760" checksum="90559C3BD295DFAF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRN1</accession>
    <name>A0A8T0IRN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G014600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6399" checksum="2470A54FFD7A94CA" modified="2022-10-12" version="1">MMRIAVFTLRVYDSGHEELARCISISQCDCSLLSSSTNYGIELRQFSSGGLKPMLDAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUT9</accession>
    <name>A0A8T0IUT9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G126400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="47" mass="5168" checksum="F03A23659604F8EC" modified="2022-10-12" version="1">MRGLLTTPAPPLFSAHLRYRPTSTARCRTSEIPNPKTSGPTRRSASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV57</accession>
    <name>A0A8T0IV57_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G177500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035842365" description="Secreted protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="118" mass="12965" checksum="4FAE53F01B3AEA41" modified="2022-10-12" version="1">MRCCHGCHRWWGERWSALALALALSLASSFLAASASADDAPVTSLRLLHRTGHHTTTSPSHHITQQHTHKHTQHNNSRNTPQEQDTTTEQSTAHDLRTTVAMFGAVAGITSTPQRNPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVN3</accession>
    <name>A0A8T0IVN3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G124100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="4197" checksum="8ACACDE6FBA7C5DE" modified="2022-10-12" version="1">MWFLILHIPFRAQTLFPCCNAMTALPPRDAYENITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWY4</accession>
    <name>A0A8T0IWY4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="2">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G177700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16541">
        <property type="entry name" value="RING-HC_RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.920:FF:000053">
        <property type="entry name" value="E3 ubiquitin-protein ligase RKP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000133">
        <property type="entry name" value="E3 ubiquitin-protein ligase RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045737">
        <property type="entry name" value="RKP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045129">
        <property type="entry name" value="RNF123/RKP/RSPRY1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003877">
        <property type="entry name" value="SPRY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057987">
        <property type="entry name" value="TPR_RNF123/RKP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363:SF5">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13363">
        <property type="entry name" value="RING FINGER AND SRY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19322">
        <property type="entry name" value="RKP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00622">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25576">
        <property type="entry name" value="TPR_RNF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00449">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B30.2/SPRY" evidence="11">
        <location>
            <begin position="91"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="10">
        <location>
            <begin position="1273"/>
            <end position="1311"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="725"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="725"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0587612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1363" mass="150914" checksum="F334F6B01FB2A6CF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXU9</accession>
    <name>A0A8T0IXU9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G213100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="513" mass="56662" checksum="B33F9DF547733744" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYI1</accession>
    <name>A0A8T0IYI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G165900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="19935" checksum="52E37642CFED2A50" modified="2022-10-12" version="1">MDRVHKGYLQHNDISPGNVLLHFPEDKVSEVYIGVCDWGLASRVCETTPSRYGYPTTEARTGAFKERGTFVAPELWYTYGKPNSETSYETLRRRHLYTQAADAYSVGVVANKIWDNEDDIDLFKDTAGKARFAVALKELTNPDPKNRSTLQLVHATLTSPPYNFQIPECCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J096</accession>
    <name>A0A8T0J096_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G279000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J096"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035833935" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="25237" checksum="9B4897F817237D0F" modified="2022-10-12" version="1">MYVLVTWSSSWVSFLCLAKSTPLVASFKNASVIFRRNRTFKYFSPGSRDYRLASEVRLGNCRLHIPLRCLVIRKNQLKTTQLLKDQPREPWSSVVCNVHLSQTKATAFRECSIAHVRPSRGRPSHPISVVADACQAVSMYPLCPTREHLELDFTAVTETHKTCCHWLQRVQIQHVTKDNGIAIANANKKCVRYAHCGHSMEHGPICQQANASQRFWSPFSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3H7</accession>
    <name>A0A8T0J3H7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G103000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3H7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="326"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="62"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="141"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="113"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="164"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="598" mass="66778" checksum="54C018DEFB4503E9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3T9</accession>
    <name>A0A8T0J3T9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G028000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3T9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000023">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000067">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF64">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="180"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="371"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="511"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0589541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="655" mass="71720" checksum="212B7E0B29F3ED92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J417</accession>
    <name>A0A8T0J417_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G053500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J417"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="16181" checksum="3F325E2EF028E590" modified="2022-10-12" version="1">MSTKVHDDDDETFDEVDVILENAKAGLQMKRSLERKTRRNINLSDIPENFAHVPASSRRSHELNTSRSPTEARTPSPQVLVGGNRARYKAQRRSIVQATLRWFRDRYMGCVSAVDSKCDMCGCNVLTSVHVPSRRALRQRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5B2</accession>
    <name>A0A8T0J5B2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G071600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5B2"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF111">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035962780" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="26"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="501"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="531"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="568"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="609"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="640" mass="73275" checksum="9456DE516459D75F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5C1</accession>
    <name>A0A8T0J5C1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G072300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5C1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051983">
        <property type="term" value="P:regulation of chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044951">
        <property type="entry name" value="SPC24-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35730">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35730:SF2">
        <property type="entry name" value="KINETOCHORE PROTEIN SPC24 HOMOLOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="58"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="249" mass="28077" checksum="3EA8A978BEA2C6A0" modified="2022-10-12" version="1">MDHERELEESEETIAAMESLSSIITTDEEYVLIQQVAQNLRSLVNLCHVQQKEVKACIQGLREKVKAKEQSVLNAQKSNLKDEELEMLRNNLAEARIEEEKAQATARSLEEHLDGLEEQLQSVEAQKQTLASLASEEIQLKNEMSLFSTISGIIPDLSKKHVFAGSIQSIFHVTVTGCADFFAIFTTCILLPLFCSLIFVSFTVSIFNAVIHLNQETALLDKEDVTKFTIDCSDMSAYQQSKTIWDMIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6B3</accession>
    <name>A0A8T0J6B3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glycosyltransferases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G147400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6B3"/>
    <dbReference type="OrthoDB" id="1925022at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 72B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045:SF31">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 76B1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20856" checksum="2FA7E00275FC4275" modified="2022-10-12" version="1">MGLENSSQPFLWILRPSDSLPAGFEDRVKGRGMCYSGWVPQTSILTHPATGGFLSHCGWNSTLESVSAGVPILGWSRGADQHLICRFLVDTARVAMELQKDPPSENDVDNMVVNPMRHVTREEIAVKVRKLMREEEGSAVRARMASMRDAAAEATAAGGSSRRSLDAYVQLLRLRCRRNSTAFDQHER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J788</accession>
    <name>A0A8T0J788_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G173300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J788"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5966" checksum="BAEC785FE5C7A3FB" modified="2022-10-12" version="1">MQPSAANFQSRNDSHWLGIIIGLIRSCSMSRKHLSSTHTSHPKYQSVQIGTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J859</accession>
    <name>A0A8T0J859_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G145800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J859"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="13351" checksum="E5A6E7EF7656B381" modified="2022-10-12" version="1">MPCISSGMATIETTPGLNKAVRIRTVIAVVLFKLKPSWQPSFVSLWSIFIGVEQVISCLNLLLAPEWLSTADLRRCAIACHSLDATAWHDTLKLVNTIIDLGYSFCLSLRFLVPAAYPDTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9T3</accession>
    <name>A0A8T0J9T3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein disulfide-isomerase</fullName>
            <ecNumber evidence="4">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G237800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9T3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03001">
        <property type="entry name" value="PDI_a_P5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000050">
        <property type="entry name" value="protein disulfide-isomerase A6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057305">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45815:SF3">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24541">
        <property type="entry name" value="Thioredox_PDIA6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035810984" description="protein disulfide-isomerase" evidence="12">
        <location>
            <begin position="26"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="13">
        <location>
            <begin position="130"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0592265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="440" mass="47548" checksum="6398AF74A3A23845" modified="2022-10-12" version="1">MAKRVATAVALLFAVVLCGAGSASALYAPSSDVVQLTSSNFKNKVLGAEGLVLVEFYANWCGHCKNLAPAWEKAATSLKGIVTVAAVDADTHKDLAQQYGIQGFPTIKVFGLGKSPVDYQGAREAKPIVEYALQQVKSLALDRLNGKSGSKKSSSKKDKDSGASASVELTSSNFDKLVLKSGDTWLIEFYAPWCGHCKRLAPEWKTAAKNLQGKMKLGQIDCEAHKDIAQRYGIKGFPTIKLFGSDKESPMDYEGERSASAIESYAISQLELNVAAPEVVELVGQDVLDKECGSAAICFVSFLPDILDSKAEGRNKYLTTLRNVAEKYKRNAYRYVWTAAGKQSELEKAVGVGGFGYPAMVALNVKKAVYAPLRGAFEQEPVMKFVSEAGKGGRGIVPLQSMPPVVTTEPWDGKDGSLIEEDEFSLDELMGDDEPNRDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAS0</accession>
    <name>A0A8T0JAS0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G203200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAS0"/>
    <dbReference type="OrthoDB" id="10258478at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022618">
        <property type="term" value="P:protein-RNA complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.720.90:FF:000001">
        <property type="entry name" value="60S ribosomal protein L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_eL38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_eL38_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10965:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="8022" checksum="98BE7B169872EC25" modified="2022-10-12" version="1">MPKQINEIKDFLLTARRKDARSVKIKRSKDVVKFKVRCSKYLYTLSVFDTDKADKLKQSLPPGLTVHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDN7</accession>
    <name>A0A8T0JDN7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G296900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDN7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07815">
        <property type="entry name" value="SRPBCC_PITP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.530.20:FF:000028">
        <property type="entry name" value="Phosphatidylinositol transfer protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001666">
        <property type="entry name" value="PI_transfer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055261">
        <property type="entry name" value="PI_transfer_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10658:SF87">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22586">
        <property type="entry name" value="ANCHR-like_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02121">
        <property type="entry name" value="IP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00391">
        <property type="entry name" value="PITRANSFER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="3">
        <location>
            <begin position="329"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="849" mass="96183" checksum="C7F487DDC2EB0C54" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JE45</accession>
    <name>A0A8T0JE45_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G323500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JE45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035937401" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11853" checksum="67065DE3283FF38D" modified="2022-10-12" version="1">MRSTTSGALQTLVCLQFCTKIAQTWANVQEISSSSWLRTRSMMRSAIGICVHVSVGEITDPWINYSVAFAIRVSKLRNRVDLRLRMSLVLLLDTVMGICALNRCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G2P3</accession>
    <name>A0A8T0G2P3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G023000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G2P3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="51"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="375"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="458" mass="50949" checksum="D24C0E81E8399A7A" modified="2022-10-12" version="1">MVIVRQNSSSAMAGMWITRLGIKTHAPQHPKGDQASSGMAMGNATGTMMRRDIWVSLPDDILDRVIARLPLQSLIRMQSVCKKWKIKLRTASFIRQCEVESESVPAEWFLTFNSQHKAGSLCLAYDTHLSKWHSLPLGFLPFEITPKSPLAAADGLICLGMGWSNVGNRGPSMPTKLIVCNPVSRFWRDVPLPPQLDPAVSLISVAGLVVDRVAGTYKLIVVGEVRREDRDCKHLVAFIFDSVCQTWNSYDVELDPLDSFSFLVSHFRTLVGHLTRAVLCSAVCEGVLYCLTARPYQLHAFNVVTEEWTRLRISLPAEISGPSLVARPGRLFLVGAYRHNQQDKSNNIGIWELDQGTHRWNVVDILLEALCSSHGRYSPPKSPPKSPPRSPTRRGNVSDNDDVVLFVKWGTRFLNYNVSKKSWVWLPACIPSAAVQAGSHAAGPHHNNFLFTPSLLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4A7</accession>
    <name>A0A8T0G4A7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G047000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4A7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051026">
        <property type="term" value="P:chiasma assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055328">
        <property type="entry name" value="HEI10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47384">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47384:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14634">
        <property type="entry name" value="zf-RING_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="10767" checksum="EAC4FD57A99EB7B8" modified="2022-10-12" version="1">MKCNSCWKNLEGRSVATTCGHIFCTEDAQKILGSVDATCPLCEQMLSKSMIKAVDMAPSDEWINMVMAGMAPQSSILNLFVSGAEPVYHHLWSVASRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5D2</accession>
    <name>A0A8T0G5D2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Amine oxidase</fullName>
            <ecNumber evidence="11">1.4.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_12G095300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="11">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>L-topaquinone</name>
            <dbReference type="ChEBI" id="CHEBI:79027"/>
        </cofactor>
        <text evidence="10">Contains 1 topaquinone per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10 11">Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the copper/topaquinone oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.-" evidence="11"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5D2"/>
    <dbReference type="OrthoDB" id="5379943at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008131">
        <property type="term" value="F:primary methylamine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009308">
        <property type="term" value="P:amine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.98.20:FF:000001">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.40:FF:000002">
        <property type="entry name" value="Amine oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.20">
        <property type="entry name" value="Copper amine oxidase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000269">
        <property type="entry name" value="Cu_amine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015798">
        <property type="entry name" value="Cu_amine_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036460">
        <property type="entry name" value="Cu_amine_oxidase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016182">
        <property type="entry name" value="Cu_amine_oxidase_N-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015802">
        <property type="entry name" value="Cu_amine_oxidase_N3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008559">
        <property type="entry name" value="PRK11504.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638:SF18">
        <property type="entry name" value="AMINE OXIDASE [COPPER-CONTAINING] ZETA, PEROXISOMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10638">
        <property type="entry name" value="COPPER AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01179">
        <property type="entry name" value="Cu_amine_oxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02728">
        <property type="entry name" value="Cu_amine_oxidN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49998">
        <property type="entry name" value="Amine oxidase catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54416">
        <property type="entry name" value="Amine oxidase N-terminal region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0186">Copper</keyword>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 11" id="KW-0801">TPQ</keyword>
    <feature type="domain" description="Copper amine oxidase N3-terminal" evidence="14">
        <location>
            <begin position="247"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Copper amine oxidase catalytic" evidence="13">
        <location>
            <begin position="376"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="21"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via topaquinone" evidence="9">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <feature type="modified residue" description="2',4',5'-topaquinone" evidence="10">
        <location>
            <position position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600269-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0554486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="817" mass="90968" checksum="4D547EB6790773B1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6U7</accession>
    <name>A0A8T0G6U7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G135100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013861">
        <property type="entry name" value="TMEM115/Pdh1/Rbl19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377">
        <property type="entry name" value="PLACENTAL PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13377:SF3">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08551">
        <property type="entry name" value="DUF1751"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0554983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="10681" checksum="D458ADB2D916560E" modified="2022-10-12" version="1">MFCADWGPFLELHPLSKGLAAVLVTGYVANAFFPNAISGTFSLIPGRFIPYAWNIITPGFLETSIFGLAVSIASLLVRRHLEPFWGSREFFKFIVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7N1</accession>
    <name>A0A8T0G7N1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">signal-recognition-particle GTPase</fullName>
            <ecNumber evidence="10">3.6.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G057800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.4" evidence="10"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7N1"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18539">
        <property type="entry name" value="SRP_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="Domain of the SRP/SRP receptor G-proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="13">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="491"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="549"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="592"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00035672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0554029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="603" mass="64376" checksum="3BC282E181111635" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7V7</accession>
    <name>A0A8T0G7V7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LOB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G092400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOB domain-containing protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7V7"/>
    <dbReference type="OrthoDB" id="1927167at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004883">
        <property type="entry name" value="LOB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31301:SF87">
        <property type="entry name" value="LOB DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31301">
        <property type="entry name" value="LOB DOMAIN-CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03195">
        <property type="entry name" value="LOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50891">
        <property type="entry name" value="LOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LOB" evidence="4">
        <location>
            <begin position="10"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="123"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0554444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="205" mass="21746" checksum="E6CE604CF2103E78" modified="2022-10-12" version="1">MLGSGGQGSTPCAACKLLRRRCAQECPFSPYFSPHEPQKFACVHKIFGASNVSKMLMEVPENQRADAASSLVYEANARIRDPVYGCMGAISALQQQAQALQAELNAVRQEITRYRQHEITAAAEDSAPAVTTSAISQVPPGYQDQRGASAAPPASEANTGANTARSSKQVTVAKSEAYTSSTVPSPSSTVATSESKDRSYWSPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8V6</accession>
    <name>A0A8T0G8V6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G174300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8V6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016197">
        <property type="term" value="P:endosomal transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00052">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000261">
        <property type="entry name" value="EH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216:SF31">
        <property type="entry name" value="AT21416P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11216">
        <property type="entry name" value="EH DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12763">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00027">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50031">
        <property type="entry name" value="EH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EH" evidence="2">
        <location>
            <begin position="14"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="47"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0555511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="18981" checksum="E5E8D79ED3BEB0A0" modified="2022-10-12" version="1">MDILSTNRSNARHDEQLYRQWFDYADAGNDGRLTGDDTVKFFSLSQLPRADLKQVWAIADVKRQGFLGFKEFVSAMQVISLAQSGKDLSPNMLRNADLDSISAPTVVGLEELIEKRQQRTSPSSNGSFRSNGPSPQKSQTSQWFNQSDMFCSAQRSTFNERVDPVGMSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9E3</accession>
    <name>A0A8T0G9E3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G004300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9E3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="91" mass="9564" checksum="D0579DE518B809B9" modified="2022-10-12" version="1">MRASHGDIQAQPIYMYGDGTVHSAQCTLPSPVTSKSPVGSSQGPRAKGDTHGRGGTRIQHCSAVQCSAVGESGDGFKPNLVRLRRTLPSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9M2</accession>
    <name>A0A8T0G9M2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCR4-NOT transcription complex subunit 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G101000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CNOT11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9M2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030014">
        <property type="term" value="C:CCR4-NOT complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031047">
        <property type="term" value="P:regulatory ncRNA-mediated gene silencing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019312">
        <property type="entry name" value="CNOT11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15975:SF0">
        <property type="entry name" value="CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10155">
        <property type="entry name" value="CNOT11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="434" mass="48401" checksum="67B4AD18311F2A91" modified="2022-10-12" version="1">MLSTGETAALLAVLGDERSLDSHVSAFTLTFKRQQHFKACCCLILLLEDRRLLKQTQRLVAFYILFELYRGEQPSTNPFMSFLIDAASNEAADKAERAFLQILLMSLNNNSKELSMKSANEFISTFDPSAHKLLSGEALKSRYADKLPPEPRMSSFKKASISNTIPDPDVPPGYDLDSPEHGVPGGVAQLGAGNREAAAAALIQTSSLNGLEPPWVRPAPPRLPPQQGEMIWQIPDTQHELLWDYGMCADTSRGASIRELINRALKGALAPAQQKKVLLELEADPKLVYHCGLTPRRLPELVENNPLLAVEVLLKLMNSNQITDYFKMLVNMDISLHSMEVVNRLTTAVDLPTEFVHMYITNCISSCENIKDKYLQNRLVRLVCVFLQSLIRNKIINGTCLLVINLHAVLVRFVAARLHKWIVASLRDSLSCAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB54</accession>
    <name>A0A8T0GB54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G049500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34466">
        <property type="entry name" value="OS11G0129800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34466:SF3">
        <property type="entry name" value="OS11G0129800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="621"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="485"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="749" mass="82911" checksum="BC148862810484E4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB79</accession>
    <name>A0A8T0GB79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G015800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FLX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040353">
        <property type="entry name" value="FLX/FLX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33405">
        <property type="entry name" value="PROTEIN FLX-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33405:SF20">
        <property type="entry name" value="PROTEIN FLX-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="4" id="KW-0287">Flowering</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="81"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="189"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0555965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="327" mass="36676" checksum="E94F77FA83A6831A" modified="2022-10-12" version="1">MLQDIEKELIMSNRNRMAAQGVLNARATALSNPGLGLMRQNPGLYGNQNRPQNMGPPPLMNGPPPGVLLLEQKVTTQHSELQRLLTENQRLAATHVALRQELAAAQQEVQRMQSMMQGLQNDKEVQVRSLLEKSANLEAELRATEPLKTDVLQARSDCQKLHQHSQELGVQVRTLTAELQRARADVQVIPNLRNEIDTLRSELQRARNAFEYEKKANAEQLDQRQAMEKNLVSMARDVEKLRAELTNAEKRQRLNPGAGAAYNGIFPSSDLSYNSLQQQVFGDNYGLHSQIPLAVENGVQFPSGQTPAWGAYDMQRHVSNNHVELEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB94</accession>
    <name>A0A8T0GB94_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G052500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB94"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12401" checksum="EAFD425BB7F83B80" modified="2022-10-12" version="1">MLDQRPAYKRTAPTRQRKSILQDKPPPEIKSRLKIHRPKAQRHELHKKNPSSSLCNQRDSTQNEPKQSAFVPASFPLRLLNLPSSLRATKTRHTKEANEFCDLCYTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCV6</accession>
    <name>A0A8T0GCV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G142400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="31933" checksum="8E9739E8572CF3A4" modified="2022-10-12" version="1">MVSKCEPGKMFSVAKLETPALRSKLDYSGGSPVPSPEAGTSSRVRVPIDIAELPLDSACEPPSPSSKHSAGYHVGGKILKFLKLRKSSKSSAIVSQEALQPALTTFRFQDQGNMSKRFASVEDVDLERYHYDSDEHSENVSTSGANCERRRRNSCSTSASSSTRSSASAQSFRSMTSRSSVTTPRSSFILGSGYQSNAQLMANILISISHLDEEDENGSDHDHPTLNGPHESAWHQPRDEILAASPGGARISSAKQSSGRNTPRIGRCSLDVHLTSPGPSRRFGKLDLSRLDKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD74</accession>
    <name>A0A8T0GD74_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G123700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family. Plant F-type subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD74"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000245">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024491">
        <property type="entry name" value="Se_SelK/SelG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10961">
        <property type="entry name" value="SelK_SelG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="67"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0557366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="22235" checksum="070325EBA5057807" modified="2022-10-12" version="1">MAYVQGGDVRGQRSPWRLSIIREMLLGLLNFVLAFFKTMFSLDAHENYGKAADNGRPGAPARPAGGARPGSTAPRGINNVHTLFGSSGASGDHGNVHSINSSRSWQTKVNEAKTARKVIVVDFTASWCGPCKLMAPVFAELSRKFGQLVFVKVDVDEVQEVAAQYGVRAMPTFLFIKDGQEIDKVVGADKNDLERKCSRYATSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD82</accession>
    <name>A0A8T0GD82_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Membrane magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G002900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD82"/>
    <dbReference type="OrthoDB" id="44756at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022890">
        <property type="term" value="F:inorganic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21181">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21181:SF7">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0555788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11807" checksum="7BD9C612F6304F2E" modified="2022-10-12" version="1">MGRVDFIIGLVGALLLAHAAVSTVLYRSALKIREEDFTYPPPQVLVEVALSLALCFWAALKVPGAFLPILPDAKENRVTKLPVNGDFMIFNHRGKIFLPELVEAKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDY6</accession>
    <name>A0A8T0GDY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fucosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G132300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May be involved in cell wall biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">Golgi stack membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009969">
        <property type="term" value="P:xyloglucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004938">
        <property type="entry name" value="XG_FTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889:SF86">
        <property type="entry name" value="FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889">
        <property type="entry name" value="FUCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03254">
        <property type="entry name" value="XG_FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0557461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="581" mass="66083" checksum="F77EA9683C77BC53" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF18</accession>
    <name>A0A8T0GF18_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G171400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05265">
        <property type="entry name" value="SDR_a1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000313">
        <property type="entry name" value="Chloroplast stem-loop binding protein of 41 kDa b, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF8">
        <property type="entry name" value="CHLOROPLAST STEM-LOOP BINDING PROTEIN OF 41 KDA B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="93"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="419" mass="45683" checksum="8461E1F88BA651F3" modified="2022-10-12" version="1">MATSQAVLAQALPAASPVASSSGVSQRKPASAALAAPFKGSLAGLRCESNGAVVAKSSRLGVDIGIVKEAAGRSIARRAVVTASASATEPKNILMMGGTRFIGLFLARELVKAGHQVTLFTRGKAPITQQLPGESDEEFADYSSKVKHLQGDRQDFDGLKEKLKGTNFNIVYDINGREGKEVEPILESLPGLEQYIFCSSAGVYLKSDQLPHFEVDAVDPKSRHKGKLDTETLLQSKGVAWTSIRPVYIYGPLNYNPVEEWFFHRLKEGRPIPVPNSGMQITQLGHVKDLARAFVEVLKNEKAYNQIYNISGAKYVTFDGIAKACAKAGGFPEPQIVHYNPKDFDFGKKKAFPLRDQHFFTSVEKAEKELDFTPEFGLVEGLTDSYNLDFGRGTFRKAADFSTDDMILEKLGIKTAVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI97</accession>
    <name>A0A8T0GI97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G134500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015140">
        <property type="term" value="F:malate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00625">
        <property type="entry name" value="ArsB_NhaD_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030676">
        <property type="entry name" value="CitT-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42826">
        <property type="entry name" value="DICARBOXYLATE TRANSPORTER 2.1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="485"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="542"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="571" mass="59977" checksum="80687E12AC8AA963" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIV9</accession>
    <name>A0A8T0GIV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G010600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIV9"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926:SF347">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13919" checksum="87D2F1E56FD47A71" modified="2022-10-12" version="1">MKRAFQVFMKMVKRDVTTWTFMIGIYAASGLGKDAFQLFVEMQQEVVEPNAITFITLLDSHCAKEVHFQASKAWLATDVRVRDALIANCGSIKDANQTSFQALVYGCDFMMDSDDWSKCQEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJQ1</accession>
    <name>A0A8T0GJQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2HC/C3H-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_11G122000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SOSEKI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010369">
        <property type="entry name" value="SOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048351">
        <property type="entry name" value="SOK_DIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049899">
        <property type="entry name" value="Znf_C2HC_C3H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31083:SF6">
        <property type="entry name" value="PROTEIN SOSEKI 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31083">
        <property type="entry name" value="UPSTREAM OF FLC PROTEIN (DUF966)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06136">
        <property type="entry name" value="SOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52027">
        <property type="entry name" value="ZF_C2HC_C3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2HC/C3H-type" evidence="13">
        <location>
            <begin position="805"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="220"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="346"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="409"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="475"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="554"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="704"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="747"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="233"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="290"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="490"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="558"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="584"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0557342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="847" mass="93477" checksum="FBAB358D410FBB59" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJZ7</accession>
    <name>A0A8T0GJZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G130900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="24577" checksum="D625D31E8A5BA8C8" modified="2022-10-12" version="1">MECTRGSRLSVKQTFEIHVCVSRPVTGIAASERKKRLRFVLLGSPWFLKPFGMLLWSLLHLLLVVAGVSLIVFSAVYIPAMVLTELALWLSIDIIRMTICAICVCCLLLCGLVLLIWSLMRLSWSLIFEGERSHQIRVACRSFVEWWDINSDLSSESIRLYLMMMLGGLWLHSTCKCVKEHCQEISDDENPWSFIITLGRWCEEVVHMHDTICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK97</accession>
    <name>A0A8T0GK97_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TLC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G070900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050291">
        <property type="term" value="F:sphingosine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016439">
        <property type="entry name" value="Lag1/Lac1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006634">
        <property type="entry name" value="TLC-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560:SF0">
        <property type="entry name" value="LD18904P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12560">
        <property type="entry name" value="LONGEVITY ASSURANCE FACTOR 1 LAG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03798">
        <property type="entry name" value="TRAM_LAG1_CLN8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005225">
        <property type="entry name" value="LAG1_LAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00724">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50922">
        <property type="entry name" value="TLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="TLC" evidence="7">
        <location>
            <begin position="67"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="291" mass="34343" checksum="D5EAC6977E01D49F" modified="2022-10-12" version="1">MVSIWEHEDQPHVRDYLMAIIFATLFPVARLLLDSFIFEKYARRVIFPSGQKFMRRRKQEAGEKKVAKFTESAWKLTYYLLSTTMLLVSACNEPWFGKTEYFWIGWPNQTIKFKLKVLYAFQCGFYVYSIAALVVWETRRKDFGVMMTHHVITIFLMVFSYIDGTYRAGVSTLLVHDVSDVLLESAKLCKYSGFEVGASLMFGLFVLSWFTLRLLIFPFWIIWSISIEVAQYLDLGGRKEFNQYYFQNTLLIMLFILHVYWWVLICRMLVKLFQNSGKVSDDVRSDSEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM23</accession>
    <name>A0A8T0GM23_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G089700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035846673" evidence="1">
        <location>
            <begin position="26"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16267" checksum="60759FA81FAA4736" modified="2022-10-12" version="1">MAMLVPNQLFVLLPLAMLLVSVATSQFVPVPPVNVTVSIKSEMGDATTLNVHCRAYWGGPPIPIIDLGLQKLCNDELYSFSFQEDTAPELDRRVYMCECEVIGYLPTHQFYVHYPHYCKCLEGLCPLHVVKPEGFFCGDEKVGAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPE7</accession>
    <name>A0A8T0GPE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">LMBR1-like membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G021400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LIMR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPE7"/>
    <dbReference type="OrthoDB" id="203099at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051584">
        <property type="entry name" value="GPCR-associated_LMBR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21355:SF0">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="484"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="572"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="621"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="656"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="666"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0560880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="764" mass="85105" checksum="3044C040F435E88B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ62</accession>
    <name>A0A8T0GQ62_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G008200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ62"/>
    <dbReference type="OrthoDB" id="687943at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04216">
        <property type="entry name" value="Phytocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000003">
        <property type="entry name" value="Blue copper"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039391">
        <property type="entry name" value="Phytocyanin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003245">
        <property type="entry name" value="Phytocyanin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021">
        <property type="entry name" value="BLUE COPPER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021:SF193">
        <property type="entry name" value="OS06G0218600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02298">
        <property type="entry name" value="Cu_bind_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51485">
        <property type="entry name" value="PHYTOCYANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035787708" description="Phytocyanin domain-containing protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Phytocyanin" evidence="5">
        <location>
            <begin position="30"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="146"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="180"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0560727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="24006" checksum="0FA39BF9A75F5B77" modified="2022-10-12" version="1">MGRGSRNSKDAAVLMIALIATAVQDVAVATEYTVGNATGWDFAPTTTYYDDWASGLKFVPGDKLVFKYLPIAHNVQEVNETDYKTCNSLNPIAEYESGNDIITLAKPGTRYYICGFLGHCDQGGMRMKTTIVDQVSSTPLIPVIPPTNSELPSPMTSIIPQLPSPAAGNGTTSNPPPHSSPHGHAHPPTAAPVSVPGHSAGDPTVQVPRLLVAISLGVASAAVSLLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRJ8</accession>
    <name>A0A8T0GRJ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G079000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11367" checksum="FCDF1AAA9B9AF40B" modified="2022-10-12" version="1">MSPAGSSCLSRIHTSSSLFEPLLAHGFHPQTNPKCPFWILPEFTGTPMMRRRRKKVTLGLKLLGPIESLESDLTSLLTAATFGRYSTILQEYNNSVFNPQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXX6</accession>
    <name>A0A8T0GXX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G126700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16493" checksum="E9F4F520556136AD" modified="2022-10-12" version="1" fragment="single">LQTDKRNPQLSARRPTSSNAGAQFCDDRTKCPVTTARSRSTMMLRLLRSLTNTDARFRPLQLPEKVTPRRDTRSPQENEQLTSGTLLDSMPPASPTSYHTPPLGPSPAAQNLTDLALRVTLVSFLLQNLITSSPSSPPLRSSQPPLHPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXY6</accession>
    <name>A0A8T0GXY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongator complex protein 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G159500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ELP6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033588">
        <property type="term" value="C:elongator holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19495">
        <property type="entry name" value="Elp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018627">
        <property type="entry name" value="ELP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16184:SF6">
        <property type="entry name" value="ELONGATOR COMPLEX PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09807">
        <property type="entry name" value="ELP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="274" mass="29973" checksum="6E330B4D438E44E9" modified="2022-10-12" version="1">MMEEALGWAGDGLPPGALVMIKDCVAAKGGFFLTFFLKRLLVPSNVASGRSKVVFVGMAEPFSHYGRIAKKQGCNLIQARDNGQFVFLDMMAAGNHLTSERRREQAVSPLQRLYQIVNESVKRMQTGNENDRVVIMVDDASLLEVSAGGRSDQVLAFLQYCRAINSGHNRCSVVVLVHGDTDITYGAAGLDNGGYVEHGEQRVASLAHELDHIADVVISVDPLSTGLANDVHGQVTVVHWSDVLSNRESRKGIQTLQFKLMENNTTFFHPGGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ63</accession>
    <name>A0A8T0GZ63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G165400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Forms homodimer and may homooligomerize and heterooligomerize to form the phragmoplastin complex. Binds to PHIP1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
            <location evidence="8">Cytoskeleton</location>
            <location evidence="8">Phragmoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009524">
        <property type="term" value="C:phragmoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1240:FF:000009">
        <property type="entry name" value="Dynamin-related protein 1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000228">
        <property type="entry name" value="dynamin-related protein 1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF223">
        <property type="entry name" value="PROTEIN 1C, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="12">
        <location>
            <begin position="31"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="11">
        <location>
            <begin position="518"/>
            <end position="609"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00065858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0565111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="609" mass="68123" checksum="AF95CB5B586D49D5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZC3</accession>
    <name>A0A8T0GZC3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G040400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11179" checksum="C635F0DD57FA5D73" modified="2022-10-12" version="1">MTAQVLALALLVHDAPLPTTSLLVLSSFLPSLHCIACSQLHPSPICPSLNSCSAHSLSHSQPHSTINQSPNPYLPASQTSTALFLISQLTYNSHLFTPSSVLSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZP2</accession>
    <name>A0A8T0GZP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Actin-related protein 2/3 complex subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G048500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Functions as a component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the WD repeat ARPC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZP2"/>
    <dbReference type="OrthoDB" id="406844at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000331">
        <property type="entry name" value="Actin-related protein 2/3 complex subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017383">
        <property type="entry name" value="ARPC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10709:SF2">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038093">
        <property type="entry name" value="ARP2/3_su1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="11">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00065908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0563649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="381" mass="42319" checksum="711739E9C83CFBBF" modified="2022-10-12" version="1">MAAGGVHHLAQCITCHAWNADMSMVAICPNNNEVHIYKASVSPNAVWERVYVLDKHEQLVSGIDWAPKSNKIVTCSHDRNSYVWSLEGNEWQATLVILRLNRAATSVEWGPQENKFAVGSGAKTVCVCYFEEDNNWWVSKLIRKKHHSTITSVAWHPNNVLLATTSTDSKCRIFSAFIKGVDARKDATTAFGDVKFGEELIQLDLACCWSFGAHWSPSGNSLAYVGHDSTIHFVTDVGPTPRARSLSLRHLPLRDVLFLSETRLVAGGFDCNPMLFGSDKNGVWEFISFLDEVKPPAETKTDTMFAAAKGKFKWLGSENPSEESTLSTTHESCITMIRPLVPLSERHPENPMTLFSTSGLDGRVVIWDLNNVGDALARLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZU5</accession>
    <name>A0A8T0GZU5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G145600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044837">
        <property type="entry name" value="REM16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391:SF106">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS01G0723500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS11G0197600-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="55"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="216"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0562432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="312" mass="35281" checksum="DCC77FAA49ED48C1" modified="2022-10-12" version="1">MLPCLGLGEMISLTQFCFWRFSLLHTDTTKMTGPRHDVIAVFNKAKAIFFYKTITTSMVSDSKTNHVMYLELPTLFVTEHGEKMSQVVALVRPARCGSGKWWLRFEGRHSVNYPSRIFTFGGGWRDFVVDNGISIGEFLVFELVNTSRLVVHVYPRDDQLGVNARGFSLSADVVEDSERLNLGLGDANHKNICQNRPTRPSLPPAKVALEYSEFKKTLCATNVPNGKIAKMDIPTPFWRSHGEDKFDKKVYTLEGPWTKGDVKAYVCRTWRQTKCLFIGGWQAFCVANKLKIGDTVVFNLTGQYQFVVSVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZV4</accession>
    <name>A0A8T0GZV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">acylphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G048100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 1">
            <text>an acyl phosphate + H2O = a carboxylate + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268:SF4">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="3">
        <location>
            <begin position="73"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="161" mass="17166" checksum="3ED2E81C31118D31" modified="2022-10-12" version="1">MSSAAGVAGRSLVSCWGGSREGVTVPQFARVIVPNFDSRGRVQLRRFTRGRVLTASMSDGAQSVPASGSGSKAVNVLIKGTVQGVFYRKWTVSTAQKLGLNGWVRNCRDGSVEAVFQGPSSAVDTMVQQCGSGPSAARVWSVDVSQWDNEVPQGFEQKPTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Q6</accession>
    <name>A0A8T0H0Q6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G132400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the argonaute family. Ago subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0Q6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02846">
        <property type="entry name" value="PAZ_argonaute_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.260.10">
        <property type="entry name" value="paz domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014811">
        <property type="entry name" value="ArgoL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003100">
        <property type="entry name" value="PAZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036085">
        <property type="entry name" value="PAZ_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003165">
        <property type="entry name" value="Piwi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22891">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08699">
        <property type="entry name" value="ArgoL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02170">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02171">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00949">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00950">
        <property type="entry name" value="Piwi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101690">
        <property type="entry name" value="PAZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50821">
        <property type="entry name" value="PAZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50822">
        <property type="entry name" value="PIWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAZ" evidence="2">
        <location>
            <begin position="47"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Piwi" evidence="3">
        <location>
            <begin position="324"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0564703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="691" mass="79436" checksum="AE22ED6C8166C456" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H309</accession>
    <name>A0A8T0H309_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G134300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H309"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009445">
        <property type="entry name" value="TMEM85/Emc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19315">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06417">
        <property type="entry name" value="EMC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017207">
        <property type="entry name" value="UCP017207_TM-p85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0564724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19590" checksum="BA5F89DB579DCFD7" modified="2022-10-12" version="1">MERGSGRGARKWAVELHDANNTSSSRDAPPDPIGFSRSTVDPEETTSGKQKKENEANWKKQKAWEVAQAPAKNLMMMGFMMWMAGSTVHLFSIGITFSALWQPVSALQSIGKVFEPFQDAKTSTLLPKLLFVALNFAAMGLGLWKLNTLGLLPTHASDWLSNLAPAQSVEFSGGGLPLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H396</accession>
    <name>A0A8T0H396_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein ENHANCED DISEASE RESISTANCE 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G059300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H396"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045096">
        <property type="entry name" value="EDR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136:SF101">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-LIKE PROTEIN (DUF1336)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein ENHANCED DISEASE RESISTANCE 2 C-terminal" evidence="1">
        <location>
            <begin position="41"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="301" mass="32983" checksum="E55495600A81705B" modified="2022-10-12" version="1">MEQNESKGQVDGEAKELEWTEELKEGGSLSYTDVSDNSTGWTSIPGDFFTVRGPQYLTDRVKIPGGESLLQPLALDWLKSSARIDNVLKLPNNRVMSGLDQAVKAGAKDPFVWAFNLQVPSKEHYSAISYFVSYNKFEEGSVGDRFLKGDDALKNTRLKLIANISEGPWIVKKAVGEQAICILGRSLTCRYLQGTNFIEVDVDIGSSIVANAIVHLAIGYLTTLTVDLAFLLEAQTESELPEQILGTVRLKKMDLAAAVPVELLSKDPLNSEGSSFQSRIWKGISTFMQPSLQGNSDDDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3E9</accession>
    <name>A0A8T0H3E9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G017500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3E9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF79">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0565840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="241" mass="27053" checksum="9290E5D089F8C8E3" modified="2022-10-12" version="1">MGSGLPPQLASIEKEVRDIFKVLTSGFQKLDQTKDEGKQTKQLEGLTAKMREAKRLIKEFDREMKEEEGNINPESNKLLNEKKQSLIKELNSFVALRKTYTSSIGSKHELLDGVSHAGSGRDMSSQEHILTGEPQVDERIETIERTDKVMRNTTNGAETATIVKVEPEQVTKLKSKVDTSEPSTGIRKMARNRCILLILLLILLGIIVIIMLKVVQPDDKVQSSAPTPLNRRLLMTTLDFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4U8</accession>
    <name>A0A8T0H4U8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Origin recognition complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G189500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the origin recognition complex (ORC).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the ORC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4U8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007220">
        <property type="entry name" value="ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056772">
        <property type="entry name" value="RecA-like_ORC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056773">
        <property type="entry name" value="WHD_ORC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14052:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04084">
        <property type="entry name" value="RecA-like_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24882">
        <property type="entry name" value="WHD_ORC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 2 RecA-like" evidence="7">
        <location>
            <begin position="144"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="Origin recognition complex subunit 2 winged-helix" evidence="8">
        <location>
            <begin position="372"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="69"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF24882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0565424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="49153" checksum="9B4C00F9C09A70A9" modified="2022-10-12" version="1">MDGRRGVKRACSDDDEPEYTPKKKRGRPRKSLAAEQTPERSVAAEQTPKRGRGRPPGSRKSLAAELSPEKSNVGEQTPAKTPKAVNFLDLEENVGATPQSYFRVKEGSGVGKRLANRIADIGIVEEQDLRDAIAKLSPKHEKEQAALLESYRTFYHKWYFQLRCGFGLLMYGFGSKKKLLEDFATSELRDGAAVVVNGYLSNVNIKHVVYTVVNTLWEARKKGKASNKAKQDSPVSSNSLVDLLGSLTDDDDDSTHIYVIIHNIDGPGLRDDDVQQTLANLASSKHVRLVASIDNINAPILWDKQMARNQFKWLWLHTPTYAAYKVEGACVPLLLAAGAATKSARSAILVLRSLTPNAQSVFRVLGEFQISHPEDQGLPLNRLYTACREQFLVSSEVTLRAHLTEFKDHELLKFRRGVDGQDCLYIPLPNEALSKLLEDITS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N1</accession>
    <name>A0A8T0H5N1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytosine deaminase</fullName>
            <ecNumber evidence="13">3.5.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Cytosine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_8G192700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the hydrolytic deamination of cytosine to uracil or 5-methylcytosine to thymine. Is involved in the pyrimidine salvage pathway, which allows the cell to utilize cytosine for pyrimidine nucleotide synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>cytosine + H2O + H(+) = uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:20605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="12">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; uracil from cytosine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.1" evidence="13"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004131">
        <property type="term" value="F:cytosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019858">
        <property type="term" value="P:cytosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000016">
        <property type="entry name" value="Cytosine deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF190">
        <property type="entry name" value="CYTOSINE DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="16">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00050113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00074321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00084039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0565468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16527" checksum="65CCF00CFEEF72CC" modified="2022-10-12" version="1">MVRSEDYQAMLDVAIAEARLGLAEGGIPIGAAMFDGEGNLLGRGHNRRVQENDPSVHAETDAFRKAGRQRSYRNCTMVTTLAPCWYCSGLVRQFNIGTLVVGESVNFQGGAQWLRDHGVKVIDLQSSECVDLLANYVVANPAIWNEDIGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9M9</accession>
    <name>A0A8T0H9M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G106800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22464">
        <property type="entry name" value="KH-I_AtC3H36_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF184">
        <property type="entry name" value="CCCH-TYPE ZN-FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14608">
        <property type="entry name" value="zf-CCCH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="82"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="163"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="350"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0567054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="40838" checksum="8DBB967DB2CFD913" modified="2022-10-12" version="1">MGSAAYEPALKKARTFSVTPISVDVNNGFGNENGAGAQDQANGDLDCRRFGTPEGCPYGTKCRFKHGPADDRPIEQPVSALGSKTKPCTKFFSTSGCPYGEGCHFLHYVPGGIAALGMLPIGVGTPTALTPTSAMRTVLGGFGPTATTNLLGTTTDPSVTVGGYKTRLCNKFSTTEGCRFGDKCHFAHGESDLRPSNVRSNGVDYLGNCTYQNWLSYFQEQGAYANGGATQLLPPVANAIYYGEPTPPGVPATAAAAAYGLNNGANTKISIEAVLAGAIIGKAGANVKQISRLTGCKLSIRDHESNASMRNVEMEGTYEQIERATEMVRQFLTHRDVAVPLRAAAIASHNYKTKLCENFSQGTCTFADRCHFAHGATELRPLTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9V9</accession>
    <name>A0A8T0H9V9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G136100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9V9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="379" mass="40488" checksum="2C7A982D91FD94B7" modified="2022-10-12" version="1">MAMASLSCPHLSAPALHLASRRRFTSLPVHLGVLTPHEKAASVSSTTRAGGSAFRFAVRAVSVSGDTEQKESDVKEADEKKRTAYRPIVILPGLGNNTGDYNELVASLAARGLTAVTAKVSRPDWLRNASGILDASYWKGTLQPRPTLDWYLERIKNAIQEAKAMAPESGKVTIVAHSAGGWLGRVYMADFGTEDVALFLSLGSPHLPPPRNVPGVVDQTRGLLYYVEENIPGAFHAPDVKYVCIAGRYLKGDRFFPGNAATVAPTGLGTVDTEVGSAAVSAAEEGKLEAGVGEVIEDGDVKPAPPTLRARIVGQGYKQVCGQADVWGDGVVPEVSAHLEGAENLTFEGVYHSPVGASDERPWYGTSKILDQWVHYLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDV6</accession>
    <name>A0A8T0HDV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G111500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6647" checksum="D399C6E27318EC4F" modified="2022-10-12" version="1">MFLGDVHGSDKTAISGSINVSQAGMITWATVTVGLYFHMPIVQTSDRHENHATWCPVELST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF09</accession>
    <name>A0A8T0HF09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G076100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044821">
        <property type="entry name" value="At1g28695/At4g15970-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46038">
        <property type="entry name" value="EXPRESSED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46038:SF38">
        <property type="entry name" value="GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="2">
        <location>
            <begin position="123"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="377" mass="42577" checksum="07E5262F235AB3CE" modified="2022-10-12" version="1">MKPRARTVVVVALVVTLFALPYLFLFRPSAEQFLCAISARSIMGGNSDVSSVALIPEQGIAESEDDGVDGSAEMAALEAMLASAATPDKTVIITTLNQAWATKGTMIDVFLESFHKGEGTQFLLNHLVIVVLDQRSHERCREVHGHCLMLKTAGVDFSGSKGFMSKDFLKMMWRRMSLLRSILELGYNFVFTDADILWFRNPFEHFANNTDFQISCDKNRGNAWSLQNKPNCGYQYARSNERTIAMYRHWCRGGDANPDIDEQSLLNRMLKSKEFTTYKVEIRFLPTERFSGFCQKSKNMSRVVTMHANCCTGLDNKVHDLRSALSDWEARKSLPPGVNTSEIELWHVPSACRHSLWPSPPPPVPELDPEFIVENRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH02</accession>
    <name>A0A8T0HH02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G180000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH02"/>
    <dbReference type="OrthoDB" id="1154031at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000006">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000044">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000030">
        <property type="entry name" value="26S protease regulatory subunit 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="180"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0570680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="405" mass="45646" checksum="F31334836F328C86" modified="2022-10-12" version="1">MGRAEEAPNRAVRSGEGLRHYYLSHIHDLLLQLRVKTHNLHRLEAQRNDLNSKVRMLREELQLLQEPGSYVGEVVKVMGKTKVLVKVHPEGKYVVDLDKSIDINKITPSTRVALRNDSYVLHLILPSKVDPLVNLMKVEKVPDSTYDMIGGLDQQIKEIKEVIELPIKHPELFESLGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKYIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARVESGNGNGDSEVQRTMLELLNQLDGFEASNKIKVLMATNRIDILDQALLRPGRIDRKIEFPNPTEESRLDILKIHSRKMNLMRGIDLKKIAEKMGGASGAELKAVCTEAGMFALRERRVHVTQEDFEMAVAKVMKKETDKNMSLKKLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI65</accession>
    <name>A0A8T0HI65_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_6G064300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE associated with ER-derived vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the BET1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI65"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000033">
        <property type="entry name" value="bet1-like SNARE 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="15">
        <location>
            <begin position="33"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0569082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13904" checksum="E81A86D0501D82FF" modified="2022-10-12" version="1">MNPRREYRANRSQLLEMEEGGLRTSAPYASSAEIAEQENERGLGELHDRVNILKRLTGDIHEEVESHNKLLEGMGNAIDVSRSLMAGTMDRFTKVFETKSSRNIATIVASCVVVFLLVYYLTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJB2</accession>
    <name>A0A8T0HJB2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G193900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01641">
        <property type="entry name" value="Bacterial_IMPase_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000021">
        <property type="entry name" value="Inositol monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000013">
        <property type="entry name" value="Inositol monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0570874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="387" mass="41990" checksum="3D443FA68809DB66" modified="2022-10-12" version="1">MSSVSTIANSCSRGNSIVFVADKQTCRSKLCTSSLSFKPKFRSLGLEAELSSSGLVSMCSGCLRGRFGSERCFHSGDGVGRHSAIGIGCRDARQRHICASSEQLGGMAVEESVCDESMDRFVEVVHKLADAARVITLKYFRSKFQIIDKADLSPVTIADRSAELAMRELLAEHCPSHSIYGEEWGLTEPEGGSDYVWVLDPIDGTKSFITGKPVFGTLIALMHKGVPVLGVIDQPVLQERWLGIQGRVTTLNGVEIQTRATTLLKDSYLYTTSPHLFAGDAEKAFIRVRNEVKVPLYGCDCYAYGLLAAGHVDLVVESELKPYDYLALVPVVEGAGGVITNWSGQKLRWLPEVGEVGIEVIAAGNASVHEAALQSLAWNEKTTRAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJY5</accession>
    <name>A0A8T0HJY5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G211800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18725">
        <property type="entry name" value="PIN_LabA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35744">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35744:SF2">
        <property type="entry name" value="OS06G0166200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="3">
        <location>
            <begin position="220"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="431"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="474"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="483" mass="54901" checksum="E247543CB417741F" modified="2022-10-12" version="1">MELCVSSQQICLSRSLVGNERRRNYTGACIGIGSNCRLHVNLRGRGGAMAALCNFNVVSCVRIFSAVDSISEIGNRRRTRLVSKFTRRPLEFYRNLDLRKRIVVRENFPICSVYDSSVEGGDAAEPGAEIDEEGEEEGKKRTVGVFWDLDNKPPKGVPPYKAAISLRDLASEFGLVVDMVAYANRHAFTYVPQWIRDERQERKRLNTLEEQGIVTPEEPYRCQYCGRKCLTYLKLKKHFKQLHERERNKRMTHLNHLKGGKRQRYKAKLAEKEDKYQAIASQLLAPKTGYGLAPELKRAGVYVRTVEDRPQAADEALIKHMNVYINRGLETLVLVSDDSDFVNILRLASMKNLQTIVIGDTMTLSRHADISFSWDEVASGRAQSAAAEAHKEWANKAALLRELEDDSDLYPEQEDSEFVPLRSNSSLAVFSEDEDWESDDDADGSTWEDDSDDDDGDENDEESAFEDFSPWSRRVADESNKVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLC1</accession>
    <name>A0A8T0HLC1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ENT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG025400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.40">
        <property type="entry name" value="ENT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033485">
        <property type="entry name" value="EMSY-LIKE_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005491">
        <property type="entry name" value="ENT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036142">
        <property type="entry name" value="ENT_dom-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432:SF22">
        <property type="entry name" value="OS10G0436850 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432">
        <property type="entry name" value="PROTEIN EMSY-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03735">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01191">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158639">
        <property type="entry name" value="ENT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51138">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENT" evidence="4">
        <location>
            <begin position="45"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="191"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="305"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="448"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="199"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="478"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="517" mass="56018" checksum="D1D63492F0090713" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMP1</accession>
    <name>A0A8T0HMP1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">40S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG052600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.50:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.910.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="entry name" value="30s ribosomal protein s13, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_uS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="Rbsml_uS13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_uS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_uS13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_uS13_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003140">
        <property type="entry name" value="PRK04053.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF3">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="S13-like H2TH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="152" mass="17623" checksum="B5C9FB94728E7B5F" modified="2022-10-12" version="1">MSLISGEEFQHILRVLNTNVDGRQKIMFALTSIKGLGRRFANLVCKKADVDMNKRAGELSAAELENLMVIVANPRQFKIPDWFLNRKKDHKDGRYSQVVSNALDMKLRDDLERLKKIRNHRGLRHYWGLRVRGQHTKTTGRRGRTVGVSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNY8</accession>
    <name>A0A8T0HNY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG113000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="14914" checksum="1F3FE0B8A9C86F4A" modified="2022-10-12" version="1">MQFDQSAANVSTYRSSAFLNFQRGATPPYAVREAFRINALETTVQRMASDLSTSNQQILEVKELLPCLINPHLQQQPSAPSPNLESSLPPAACTPLAPTGTDVAAQRSSARNQHTSLPLQEPEIPEAHVTLTSTMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPP2</accession>
    <name>A0A8T0HPP2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG107400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="18865" checksum="1A768027180E256A" modified="2022-10-12" version="1">MHTLLSPYFVLTGRAPRLSSDNIRKKFQEVIDEHASLEEMSAMIMDRVQLLEDVHKAVAMNIATAQRKQQEDYTKRKEKSKRFPHLKINNAVKMYVPGKRRALDWNWEGPFGFKMYSRELDAADDEAARLCQLLDAAVKLWKRARRDVRVYEGEQLGGEGAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTE2</accession>
    <name>A0A8T0HTE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_VG250300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBR family. Ariadne subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the RBR family. RNF14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="5"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20341">
        <property type="entry name" value="BRcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20354">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23820">
        <property type="entry name" value="RWD_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000358">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047548">
        <property type="entry name" value="Rcat_RBR_RNF14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="16">
        <location>
            <begin position="189"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="381"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="385"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0574282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="696" mass="76674" checksum="F95820A1D8483924" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW56</accession>
    <name>A0A8T0HW56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG338900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="252" mass="26780" checksum="8E643F140CD24D70" modified="2022-10-12" version="1">MEGGREGGREEKEREGGKGEGGREKGGREGKEREGGRERRGREGGKGEGGREGKREGKEREGGKGEGGREGKEREGGRKRRGREGGKGEGGREGKREGKEREGGRERRGREGGRGEGGREGEERGGGKEREGERRGRGERRGRGKGEGGGKEREGERRGRGKGEGGGKEREGERRGRGKGEGGGKEREGERRGRGKGEGKEREGEGGGKGGREGEGKGRERGAKGGREGEGKGGGAGAGEGRRVFIFFKNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX02</accession>
    <name>A0A8T0HX02_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG308100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="41" mass="4589" checksum="7771336DEFA09033" modified="2022-10-12" version="1">MTTGITGLMCALELQLDLFRHTSAIANTFPVCLMTLLMFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY40</accession>
    <name>A0A8T0HY40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G031000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035724913" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="6643" checksum="D5F0C0A7B2F3E8F3" modified="2022-10-12" version="1">MITSSKPKIFLLLQLSSLCGVAQCACCGTVLNLITLVMFTKTCTIPLYGNTITGLPHGKQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY66</accession>
    <name>A0A8T0HY66_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G019500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="6033" checksum="6DFDAD993685DAFA" modified="2022-10-12" version="1">MGGRLRLEAEECCHWHYSRQCMVARRGDLAMLKGGLFRDWWTHFRGSKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZB0</accession>
    <name>A0A8T0HZB0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G021900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="299"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="794" mass="90897" checksum="9E952E3667639E36" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I031</accession>
    <name>A0A8T0I031_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G049100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I031"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF48">
        <property type="entry name" value="OJ1485_B09.5 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035728130" description="Exostosin GT47 domain-containing protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="7">
        <location>
            <begin position="73"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0576023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="455" mass="52863" checksum="AB7C8DA486730169" modified="2022-10-12" version="1">MWKFSKKPVFWVLLVVVIASVLTLPGLLSRDSVEYYFNQLSDRGDSSDKASSWFPRSSSNNTRNDSKTECTLPLKVYMYELPRKYNMGLLDRDDPNQELPWTNPVAPPWSFEYEVNKQHSVEYWLMVYLLNARDRKNEKMAAVRVNDPNDADVFFVPFFSARSFNNYGHNMIGPDTEIDKSLQAGVVDILHKSEWWQASQGRDHVIVAHHPNAFRHYRDMLNQSIFVVADFGRYNKTVARLSKDVVAPYVHVLPSYNQDNSIDPFSARKTLLFFRGRTRRKADGWVRAKLGELLMNVTDVEYTDSLASADGLSTSTEGMRSSLFCLHPAGDTPSSCRLFDAIVNHCVPVIISDRIELPFEDDLDYNEFCLFFSSEEAIKPGHLLGTLRGMKRERWLQMWEKLKAISHHFEYQHPSKKDDAVNMIFKQVQRKVPALKLGIHRSKRLRIEDWLRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1N4</accession>
    <name>A0A8T0I1N4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G091400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1N4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677">
        <property type="entry name" value="AP2 DOMAIN CLASS TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677:SF75">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="262"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0576583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="466" mass="50658" checksum="784881E98208BA87" modified="2022-10-12" version="1">MALQDMLVGGRSCSHIISLKRKWDDNAPEMIFSRKSPACLRCSATAVQPLVCDCCSIIPCSSSTSKDHQHHQNWCGDLLALGPDSNDVLHTNFNHEVLQDSSELRFRPACPTHQQKGLDGIAAVVGQSILFGTSISTGREDLCTVTDHQPPSWNSCNLHPSETSGLNVLSRGSSLRCNPERFIAEPFISTVEDCSKAMSHNLLIDSGNSFFDASGRRPNVFSFQQSVGGHEPAEAICKPEGSSTSGDRVPSGESAGTSGRSAFRGVRKRPWGRWSAEIRDRIGRCRHWLGTFDTAEDAARAYDSAARALRGAKAKTNFDPQSKAKARLANLTSMKEQLRWASCNPSSSMGSATILPVTLSNPSHHRSAEVMSYPTMKAGAPTYQFQAITPPKLNCNFSATQELDLKLGLMPDCSKRSCCSSSLESTPESSTTYQSPDQCSDHFLSTSISHTYSSFSSEFACPAYHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I277</accession>
    <name>A0A8T0I277_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc-ribbon domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G164600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I277"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900150">
        <property type="term" value="P:regulation of defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040244">
        <property type="entry name" value="EDR4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055126">
        <property type="entry name" value="EDR4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021480">
        <property type="entry name" value="Zinc_ribbon_12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31105">
        <property type="entry name" value="EXTRA-LARGE G-PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31105:SF42">
        <property type="entry name" value="OS02G0258300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22910">
        <property type="entry name" value="EDR4-like_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11331">
        <property type="entry name" value="Zn_ribbon_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enhanced disease resistance 4-like N-terminal" evidence="3">
        <location>
            <begin position="56"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Probable zinc-ribbon" evidence="2">
        <location>
            <begin position="561"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="455"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="612"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="148"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="480"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="502"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="612"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="755"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="995" mass="108792" checksum="5885E4FA57D7CEC4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2L7</accession>
    <name>A0A8T0I2L7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G138000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2L7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12198" checksum="F29F9EFE8497FE11" modified="2022-10-12" version="1">MPCSSVTQCQQGHLKEHVFNVQGAASGPISVHRNIQPHLRICALGPKSHDDMVRFQTAGKTHSSHFILLFVLEHILHIDRGLVSITNFSPSIHSKQQGLASVPTHLYCSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2V6</accession>
    <name>A0A8T0I2V6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G145100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2V6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="555" mass="63304" checksum="25EB3F442932CFD5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2X0</accession>
    <name>A0A8T0I2X0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G183800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2X0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11372" checksum="D319C20B912443CE" modified="2022-10-12" version="1">MFLHVYRQKYLQGVGNLLVSHMGHEREREREHEADRGAALLCCRCGQFCDTPLLQLGWGEAFGRGGLLPSLWKSLLLLLFWSLWCCCVCMVFVHFSALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4I0</accession>
    <name>A0A8T0I4I0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">RuvB-like helicase</fullName>
            <ecNumber evidence="12">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G157700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="12"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4I0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002221">
        <property type="entry name" value="RuvB-like 2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000002">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="68"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0577458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="51969" checksum="2D6AB5BF4A25111F" modified="2022-10-12" version="1">MTTTTDVKVSEVKDLTRVERIGAHSHIRGLGLDDAFEARNVSQGMVGQKAARRAAGVILELIRQGKIAGRAVLLAGQPGTGKTAIAMGMAKALGEETPFAMMAGSEIFSLEMSKTEALTQAFRKAIGVRIKEETEMIEGEVVEVEVDKPAAGGVSKTGKLTLKTTEMETVFDLGQKMIESLVKQKIQHGDVIAIDKASGKITKLGRSFARSKDFDAMGPATKFVQCPDGELQKKKELVHVVTLHEIDVINSRSQGFLALFSGDTGEIRSEVREQIDGKVAAWREEGKAEIVPGVLFIDEVHMLDIECFSWLNRALENENAPILVVATNRGITRIRGTNYKSPHGIPIDLLDRLLIISTSPYTEQEIRKILDIRCEEEDVEMSEDARDLLTKIGHETSLRYAIHLINAAALACQKRKGKEVEMEDIGRVYSLFVDVKRSTQFLMEYQEQFMFNEMSPDDEMEEDSAQHTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4U2</accession>
    <name>A0A8T0I4U2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G162100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4U2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33782:SF5">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33782">
        <property type="entry name" value="OS01G0121600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="18457" checksum="1BBFBEFB9693409C" modified="2022-10-12" version="1">MALAVQMTSQMAVQLASPWTASSSSSCRAVKVLGGFRKPLRCSRRRAGVARASGTAEPESAGTGGSGMVDSNMMVLRKRIQSIRVQESIYDIPADWAEWERNSYASYRADICLLLSTMQGQLLTMRPGTVVLFASVLMAVLPVMSIMFVSAVGTQLWSLHCALLELGASLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I664</accession>
    <name>A0A8T0I664_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MaoC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G033800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I664"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:(3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044594">
        <property type="term" value="F:17-beta-hydroxysteroid dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004300">
        <property type="term" value="F:enoyl-CoA hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03448">
        <property type="entry name" value="HDE_HSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054357">
        <property type="entry name" value="MFE-2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078:SF56">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13078">
        <property type="entry name" value="PEROXISOMAL MULTIFUNCTIONAL ENZYME TYPE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22622">
        <property type="entry name" value="MFE-2_hydrat-2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peroxisomal multifunctional enzyme type 2-like N-terminal" evidence="2">
        <location>
            <begin position="43"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="210"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="37236" checksum="828DA557B2713833" modified="2022-10-12" version="1">MRAHPNDNKFRPALLSYMLTVMASLPRIDPAQVLAYEFPQSRFTYTERDVALYALGVGAAGADPCNPSELPFVYHPDGQSSIKVLPTFTVLYPVGFLDVISSISGLHYDPNLLLHGEQYIEIYQDIPTNATIRNSIKVSGLHDKGKAAIFELETISYNDDTGALLCMNRSTIFLRGAGGFSTSGKPYSFSNRTNAGIVTRTATKKDLAGERSPDSVFEDRIQPSQALLYRLSGDYNPLHSDPSFAKKAGFQQPILHGLCTLGYATRAVIKCLCEGDPRLVQSVQGRFLLHVFPGETLITEMWKDEGQNRVDYKLKVKERNKVVLAGSITLKPALSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6S5</accession>
    <name>A0A8T0I6S5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G019900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6S5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="234" mass="26595" checksum="038444436D6BE4BF" modified="2022-10-12" version="1">MTKGKESPEILAEGSKSGDTQGLKSSGDPQSSSSISDENNSRLEDLKTERKEELQNAALYTARCTSHKTDLYQLLGFYTVFQGVVFNTVATSPKLTCQTSLLPAILCILAFVGVLCSVLYKLDDYKTDKQKLIKSEHLAKFVKNKIEKLKDSGNLDFNDLYTAFKEKQNKKIKEDEWTRLMFKGILVLFLISFTATVLTCCIIVRCWDLEHNELMLCAFNRCWEKNVTVHMHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7H9</accession>
    <name>A0A8T0I7H9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G059200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7H9"/>
    <dbReference type="OrthoDB" id="62312at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039297">
        <property type="entry name" value="COX7a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35308">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35308:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02238">
        <property type="entry name" value="COX7a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0578909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7370" checksum="E7F1296930CC51A8" modified="2022-10-12" version="1">MASENIGKLPEWVMERQKAFQSVHRLTHLKAPGDRLTSVIIPGLLVATGLSLMGRGVYHMATGQGLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8V5</accession>
    <name>A0A8T0I8V5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G096900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8V5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0579415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15573" checksum="3DDB4BB3510B5418" modified="2022-10-12" version="1" fragment="single">CAVDTQLRSTCSQLYGQLSDRADVYSFGREIGTQLNLTTRCIYPIGLLKLKEERLIEIMDSRLHVTEADAFEVQRVLKIAVMCAQVSPDKRSTMFRVVAMLAGDANVVVAPIDDSDVGPMFDFTHYQSAPENSFYCSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9M4</accession>
    <name>A0A8T0I9M4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF1664 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G169300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9M4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012458">
        <property type="entry name" value="DUF1664"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07889">
        <property type="entry name" value="DUF1664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1664" evidence="3">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12650" checksum="85CCCFC27DC07EE2" modified="2022-10-12" version="1">MTNAIAKIWQELAEVSASLSCAKNKLTSKLDEVVANIEETDKTKKAFKDTMFDTRKEAERSKDKIAEVQDLIQGLQMRISEIDDLAAPISEYETAKETSHNDELSTNIVAEET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAQ5</accession>
    <name>A0A8T0IAQ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G201300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048468">
        <property type="term" value="P:cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="41990" checksum="C74379028D8D5C5B" modified="2022-10-12" version="1">MADEEVQPLVCDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDALMKILTERGYSFTTTAEREIVRDMKEKLAYVANDFEQELETARSSSSLEKSYELPDGQVITIGAERFRCPEVLFNPSLIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQVPFRFRFLACIFDLVLCVFQCSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID92</accession>
    <name>A0A8T0ID92_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G200500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID92"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035802762" evidence="1">
        <location>
            <begin position="17"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6113" checksum="C9E9A2B9E03995F5" modified="2022-10-12" version="1">MSLSFFTLVLLVRVLSIHLICFRSANSISERISSLQIDDFQNVTACSRFSVIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF08</accession>
    <name>A0A8T0IF08_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SEC1 family transport protein SLY1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G223900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF08"/>
    <dbReference type="OrthoDB" id="10251230at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.830.10">
        <property type="entry name" value="Syntaxin Binding Protein 1, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043154">
        <property type="entry name" value="Sec-1-like_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043127">
        <property type="entry name" value="Sec-1-like_dom3a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005715">
        <property type="entry name" value="VPS45_Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="617" mass="67508" checksum="3E52EAF98141CC55" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFW5</accession>
    <name>A0A8T0IFW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G250700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044800">
        <property type="entry name" value="LEC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140:SF81">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="356"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0581428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="584" mass="63299" checksum="E2C570F61DD9B5CC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHG9</accession>
    <name>A0A8T0IHG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">KC19_3G061300</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19 25">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18 25">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RLP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000219">
        <property type="entry name" value="Leucine-rich repeat receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000365">
        <property type="entry name" value="Leucine-rich repeat receptor-like serine/threonine-protein kinase At1g17230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000111">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000627">
        <property type="entry name" value="Probable leucine-rich repeat receptor-like protein kinase At2g33170"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000416">
        <property type="entry name" value="Probable leucine-rich repeat receptor-like protein kinase At5g63930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF81">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE CEPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="743"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="807"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="1082"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="20">
        <location>
            <begin position="1098"/>
            <end position="1110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0582455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1152" mass="124860" checksum="7377701D842A56EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIG8</accession>
    <name>A0A8T0IIG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TPM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G077500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30373">
        <property type="entry name" value="UPF0603 PROTEIN YGCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30373:SF2">
        <property type="entry name" value="UPF0603 PROTEIN YGCG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="TPM" evidence="3">
        <location>
            <begin position="112"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="31591" checksum="871A789B09ACD588" modified="2022-10-12" version="1">MMAEVMARGSSTLLGSASPAVVVPTTKTTPFLGTALPSLSTGSRKSRPQCSLAVTAPKASLGDALNKAKATVGTGLSALALSAALSLGPAVPISDASEFSVLNEGPPSESYVVDDANVLNRVTRSDLKRLLRDLEERKGYHINVITLRKITTKADSFEFADTILEKWYPTLEEGNNKGVVLLVTTQKEGAVTGGPAFTKAVGDKILEAVTAENLPVLATDEKYNEAIYSTAKRLVAAIDGQEDTGGPTFKENKRESNFKSKEETESKRGQFSLVVGGLLVIAFVVPMAQYYAYVSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKI2</accession>
    <name>A0A8T0IKI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G131000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15604" checksum="775961155749383F" modified="2022-10-12" version="1">MTLLLSTPNTVLSQHVTPLHSTSLHSTPLNFSNWLCLHTLKLQHPSPNLQNPQQRLQASRHTNLSNLRTHHATNLLIQTGSHFPMLHTPHHRNLNHATSLHQSTASIPPRFGLQPSPNRDSPLFPSSNRRGLAAKWLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILG4</accession>
    <name>A0A8T0ILG4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G222200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILG4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14108" checksum="54DD05C7D108F27E" modified="2022-10-12" version="1">MQSPCAQSITAPSPRSPAIPLPPSPAPSPASTISRLMPFIRLSVSRDCHCLDSELELESEPELASELGRLESELEVGEEFEASCVVWEGGSVGLGVRACDASVGANGDSEVNCSGRHVILGGGGMVFRWGWVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM02</accession>
    <name>A0A8T0IM02_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G140800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="286" mass="32637" checksum="62F84A234C69E023" modified="2022-10-12" version="1">MATKMNGRQPPPVYTEEQPATTAGGPVFRFFFKREASEPLQVLKLRTVESSFAPAYRSWGSKVLLVWRLVVALYFVGVGILYGWIPDWKTSRVLAPVYLTNWGVVAVAVYYIIATINSVHSVCIHSKYEPLSRFWRWLAAIQIFLFELTVVLETLITILYWSFEQVGFCSVDCVTGHALGNACLIVELVFSRLPIRPRHVILTIIYPILWIASQIAWVYTDHPPAYPSTLTMRNVRSIWVCILGLVAFVLAHFLFWLIALARDKLCAGRFYPADEGKEFDHPPLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP24</accession>
    <name>A0A8T0IP24_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">alpha-1,2-Mannosidase</fullName>
            <ecNumber evidence="13">3.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_2G017800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 9A1,2,3B1,2,3) + 4 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 4 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56008"/>
            <dbReference type="Rhea" id="RHEA-COMP:14356"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:139493"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(4)-(alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 8A1,2,3B1,3) + 3 H2O = N(4)-(alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc)-L-asparaginyl-[protein] (N-glucan mannose isomer 5A1,2) + 3 beta-D-mannose</text>
            <dbReference type="Rhea" id="RHEA:56028"/>
            <dbReference type="Rhea" id="RHEA-COMP:14358"/>
            <dbReference type="Rhea" id="RHEA-COMP:14367"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28563"/>
            <dbReference type="ChEBI" id="CHEBI:59087"/>
            <dbReference type="ChEBI" id="CHEBI:60628"/>
            <dbReference type="EC" id="3.2.1.113"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.-" evidence="13"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004571">
        <property type="term" value="F:mannosyl-oligosaccharide 1,2-alpha-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001382">
        <property type="entry name" value="Glyco_hydro_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050749">
        <property type="entry name" value="Glycosyl_Hydrolase_47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036026">
        <property type="entry name" value="Seven-hairpin_glycosidases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742:SF55">
        <property type="entry name" value="ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11742">
        <property type="entry name" value="MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01532">
        <property type="entry name" value="Glyco_hydro_47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00747">
        <property type="entry name" value="GLYHDRLASE47"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48225">
        <property type="entry name" value="Seven-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="625"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="651"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="668"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="489"/>
        </location>
    </feature>
    <feature type="active site" evidence="10">
        <location>
            <position position="529"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="616"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="432"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601382-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0585510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="737" mass="81039" checksum="13E69B399D1EA088" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPA0</accession>
    <name>A0A8T0IPA0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G197700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPA0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050295">
        <property type="entry name" value="Plant_2OG-oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47991">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="5">
        <location>
            <begin position="221"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0584263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="372" mass="40933" checksum="34520B0235E3ACF2" modified="2022-10-12" version="1">MGLDIPLAHSPNMQSGNSIDTTKLEDLLISVVESGIDQVPPDYIKLPHDRVSRSLNSEGPQEQIPVIDLAMMEDGGPGKRQVLAEIVRACEDWGCFHMINHGVPAAVMDAALDAIKGFFALPAAEREEYRQTKNAGKGCGRSYTGQGVVRDWNNLLILTDFSGEEDRKSDRGSFYDLVLAKPPGAQEALENYGQSVNILIERSFSLVSEALGQTPEFLTRKHTSRFGTVTTHYPPCPQPDLVMGLRPHEDGGIFTLIHLDEVPGLEVLKDERWVPVTPVAHSFVFMIGDLLQIISNDRFKSVTHRVVAGPIARTVMGNFAVTSNDSVIQPAAEFCSDLKPPAFRPVVFLDYKKKLVGTGTHSKRVEAYRLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR54</accession>
    <name>A0A8T0IR54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G002700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16620">
        <property type="entry name" value="vRING-HC-C4C4_RBBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025829">
        <property type="entry name" value="Zn_knuckle_CX2CX3GHX4C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF27">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13696">
        <property type="entry name" value="zf-CCHC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="10">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="211"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="8">
        <location>
            <begin position="296"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="9">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="423"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="514"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="684"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="169"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="426"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="697"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="763"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="804"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="902"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="931"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="942"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="976"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1006"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1034"/>
            <end position="1048"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0585306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1048" mass="116935" checksum="C6944D4AE6594095" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITV2</accession>
    <name>A0A8T0ITV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Polyribonucleotide nucleotidyltransferase 2, mitochondrial</fullName>
            <ecNumber evidence="3">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Polynucleotide phosphorylase 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Polynucleotide phosphorylase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_2G143800</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>RNA(n+1) + phosphate = RNA(n) + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000958">
        <property type="term" value="P:mitochondrial mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02393">
        <property type="entry name" value="KH-I_PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11363">
        <property type="entry name" value="RNase_PH_PNPase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11364">
        <property type="entry name" value="RNase_PH_PNPase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04472">
        <property type="entry name" value="S1_PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000001">
        <property type="entry name" value="Polyribonucleotide nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000001">
        <property type="entry name" value="Polyribonucleotide nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.70:FF:000020">
        <property type="entry name" value="Polyribonucleotide nucleotidyltransferase 2 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000189">
        <property type="entry name" value="Polyribonucleotide nucleotidyltransferase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="entry name" value="GHMP Kinase, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008805">
        <property type="entry name" value="PRK11824.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252:SF16">
        <property type="entry name" value="POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="Ribonuclease PH domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="10 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="S1 motif" evidence="17">
        <location>
            <begin position="718"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="786"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="795"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00051524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0587154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="818" mass="88745" checksum="13CD68D5D34DF807" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU39</accession>
    <name>A0A8T0IU39_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G046600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU39"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="26651" checksum="39FE73BDF01D5CE7" modified="2022-10-12" version="1">MHSSEAALTTTLRHPQLHAIMPPPIPTPPELRPLAIPPHQQNPRRARHATHSLNQCLPTDCATATPPNRPTHHRIGPRRNSDARPPQPYPTDQVIPSDDLPHHPPPCPCSACAITQCIHHHGQPPHAVRPSPLSHTELRTTTPEAGVENDTGGFPRKAEPSLASPRIATTRCRRQSERRELRIRRLPRDPPCSFLRLHRPSLVASPRAPLPLVLSRRRRHRRMRLHFSRRASFPPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU79</accession>
    <name>A0A8T0IU79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G098500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="7385" checksum="2F5CF7642828D02A" modified="2022-10-12" version="1">MECGTVRCKSWFLCRRSLEDFLVSGCMCESSVFLLHVSGIMLLKWQSGTVLPGDNCKFVAVRKSGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUT5</accession>
    <name>A0A8T0IUT5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G123300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035821544" evidence="1">
        <location>
            <begin position="30"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="20273" checksum="E199B5F0202B0FC8" modified="2022-10-12" version="1">MAHSGARQCSLSVAAALCLVTMFFAQASAQGVAPTVAPILAPTVAPTIAPTVAPTVAPTVAPTVAPTVAPTVAPTIAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPTVAPATPPPPPMLPAPTPSLIPDVPNAPAPAVSPPGNGASTMAPSVSILLMSVAAYLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVE5</accession>
    <name>A0A8T0IVE5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PB1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G128200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVE5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PB1" evidence="1">
        <location>
            <begin position="18"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="23685" checksum="5C49352E12672852" modified="2022-10-12" version="1">MDPHTYIFKIKHGDVLRRITVRAPYDIRYGLHGEGPDITFSQLESTIREAFSIPIASKVSIVYTDKDNDEVTMVDDNDIQDACVYQKLNPVRVRVLLREELQSSMYDARPSESLAVDPPPWADDILMKLDQLLLAVNKPLIEPGVASVIPASTKTEDHVVDVDDSPINGSTIKAAKDGSSLNLRVDSASSGFDSDFLRRAAILRQRGMTDDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY96</accession>
    <name>A0A8T0IY96_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G221700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805766" evidence="1">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="7087" checksum="1807CC54A161729C" modified="2022-10-12" version="1">MIVSMCICDGLLICFLSFPWADWACDWSGIATGRWGLFRFDWSCGRFRNLSPSMLLGMQMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0E5</accession>
    <name>A0A8T0J0E5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fucosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G282300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May be involved in cell wall biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">Golgi stack membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0E5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009969">
        <property type="term" value="P:xyloglucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11340:FF:000005">
        <property type="entry name" value="Galactoside 2-alpha-L-fucosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004938">
        <property type="entry name" value="XG_FTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889">
        <property type="entry name" value="FUCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889:SF2">
        <property type="entry name" value="FUCOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03254">
        <property type="entry name" value="XG_FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="542"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0588977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="562" mass="63230" checksum="D7971FED45A3BC50" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J133</accession>
    <name>A0A8T0J133_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G012300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J133"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="2">
        <location>
            <begin position="5"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="18565" checksum="FBC5EA525A5010F9" modified="2022-10-12" version="1">MKATPTSQVASMLRNTMLNLKQRKGVSLAQIRKHVEANYSTKLDTTNKKRLATALKGLVQTGKVEKTPAGVYKLKKTAEQEGDKAEVPNRRRRLFPKGYCKTHRHYHRSRRHRRRRSHRRRRSRHRRRRHSRRRRRFPKGYCKTHRHYHRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3Q3</accession>
    <name>A0A8T0J3Q3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G051900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3Q3"/>
    <dbReference type="OrthoDB" id="40134at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="328"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="8">
        <location>
            <begin position="61"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0589832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="52760" checksum="9C7C7559ED021A21" modified="2022-10-12" version="1">MAGLVGEGREASAGSVETAGAVGEHGHGEGGGVLGGCNASMAVGQGWRLKGWVPSLALWKGGSVFDSWLVASAAQIGQVVLTLPCTMSQMGVAYGVPAIILYNVLGAWSVYLLVWLYLEFKARALSQGKSRPERHILQYHEVIGGLIGQWGGKVTYFFVILSLAIASVIQLIASASDLYYANASLNKREWQYIVGGVAFLAVFVPDYGHFRSGAVIGILTTTITSLYMFIAALSIGQAPGVKHTGGHDKVEFLTGATNILFAFGGHGITIEILESMRRPSRFKFVYIAVCFYTLCITIPSAVSVYWAYGDVLLKRNNAFAVLPASGWRTVAIAAMVVHQAMGFVLFSHPVFLVCEKAAGVHTKMFALRVLVRVPVVAVMWFLALAVPFFGPINSVMGAFLVTVSVYIIPLAAFLITYRTKSARQNSAVQLPPFLPKWSLMFLLNSIIIVWTVVVGIGFGGWASVTTFVRQINSFGFFDKCFQCPSPTPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3W3</accession>
    <name>A0A8T0J3W3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G113300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3W3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015171">
        <property type="term" value="F:amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000033">
        <property type="entry name" value="Lysine histidine transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="424"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="39"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0590600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="458" mass="51174" checksum="5D7D873A20C1D401" modified="2022-10-12" version="1">MATNPSMGEAFQEHLEENGHKKKVKNVDDWLPVTGDRHAKWWYSTFHNVTAMVGAGVLGLPNAMAYMTWGPGVTVLVLSWMITLYTLWQMVEMHEIVEGKRFDRYHELGQEAFGHKLGLWIVVPQQLIVEVGVDIVYMVTGGKSLQGFYKIVCKGSCGLKQHTTAWIAIFSSVHFVLSQLPNFNSIAGVSLAAAIMSLSYSTIAWCIPAAYGHSHPPLVGNQYPDYHLPDSTMVDHVFFFFNALGTVAFAYAGHNVVLEIQATIPSTKERPSKVPMWKGVVLAYIVVAICYFPVALVGYWAYGNNVTDNILLYVARPPWLIAIANLMVVVHVIGSYQIYAMPVFDMLESVLVKRFKLTPSTKLRLITRSLYVAFTAFVGMTFPFFGALLGFFGGFAFAPTTYFLPCIMWLCIVKPKKWGFSWCLNWIIIVLGTLLMVVSSIGGLYAIIKSASSYQFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J430</accession>
    <name>A0A8T0J430_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G120100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J430"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19757">
        <property type="entry name" value="Bbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="2">
        <location>
            <begin position="20"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="437" mass="49381" checksum="96AFDE47B0030095" modified="2022-10-12" version="1">MSNNSEAAGFQHGTSSSSRMKLEKCDECEEDPHSDAAVFCGKCELQLCTLCDADKHKGRKTSLHYRISIVERRVELEAMKIYNRMLSNSPSLRHGQVDADLKNKFCYFCPNERRIIFMPRLAELVQDPKARPSLVSLIGPTGVGKSFLLKYLLLVDGVERDMDMPLIGAAGDPQSTSADIHIYAGRQDSAHPLLYLDSEGRGGSKKPHGVSSLLEAIMRAKSADGGSYVDVRYEHVQTSYPRMLYIFSDVLCFVFSGNWREKLNILGPLLEWGKTASFGADNQHRPQLIIIFNKTDKETFHDDFDNFKKTFEKWIADDEQGDELLLYYSNPLAVSVPHMDFDGADKKVPSRVAKLREAIMESTQRIRTERSEGKLLFTRCQLELYMRKVAGIFSKYPTAVFDIYKAMFTDSLVVGLTGYNVELRWEGGIPPGLLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4M6</accession>
    <name>A0A8T0J4M6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G054200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4M6"/>
    <dbReference type="OrthoDB" id="1927955at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33918:SF6">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33918">
        <property type="entry name" value="OS01G0704200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="35690" checksum="F04EFA80B78218F7" modified="2022-10-12" version="1">MAMGVTSLLGRSAPAAACYDYKSKTLNVASSAQCSMSFGASTTWRRDLPSWSSIQFDPLRHAVTTQGNVLRSKRLTVAAASESSNGSPDGGKARQRTRAKEDVATLREKVSDYIEKKSGYFWLGGPILATAAVFIPPAIIPLVQLLQKNYLVGLLASFGLDILFVLAADLFFVLADKAGHHQTIAGGTAPWIGPWEYTGYPKGEPVLTKLVAYAGVAVGVLGVVLSLFVGKLAVGLPAFGSYLALIFVQVAYERLLINDRVPAYPLVPLMYTMYRFKQLARATELVAVMGGGAPLAFIIKLLTVVWTFYLGIQLTQLPWLYSTWNSNKAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7N3</accession>
    <name>A0A8T0J7N3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G131500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="349"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1616"/>
            <end position="1700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1759"/>
            <end position="1779"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="639"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="765"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1188"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="138"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="398"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1637"/>
            <end position="1657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1805" mass="203397" checksum="8812DBEEC9809739" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J814</accession>
    <name>A0A8T0J814_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G220700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J814"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12168" checksum="506D02A134B1A75E" modified="2022-10-12" version="1">MLSKYVCGWELMNLRLGFVICAGLQQWDWFGLTGNLLPRELYMEGVSRRLLYVRSEILSLLKSCLGADREGFSHNPVTAGVCKAVGICRAWSSWLMLKSKAWGPTGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J901</accession>
    <name>A0A8T0J901_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G248600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J901"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7436" checksum="A6224684D5C33B29" modified="2022-10-12" version="1">MEPERILSYYASFIPRTSELEFYKWISLFMAFWSLCAACHENSPGTRLLLRRVPVSRSKKHPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J912</accession>
    <name>A0A8T0J912_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G249600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J912"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7861" checksum="3B61519BCB210405" modified="2022-10-12" version="1">MSDAPLLRQPCPQREYSWCEAPSPGPVLFRFRFRIITAARLLPVAFSLFSRWDATGPHFALMRQGLLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB23</accession>
    <name>A0A8T0JB23_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G231000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="18917" checksum="CA306923D39570CC" modified="2022-10-12" version="1">MDAAGVEYAARLQALQADKNLYNRLKYFIHDLAVFGKDEGARLRLLQDPTANFYMSSVYFSPEQASALLSFQGREGVTLEQALQSTIARKLQQARDGSTTSFELCTSHDLAPVLQDYFGVSKAVLVEAANKGLYNKFAKEQREEQRKKPGKEQRKKPGKGQKQRNPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JEJ2</accession>
    <name>A0A8T0JEJ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G327200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JEJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="entry name" value="YhbY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040286">
        <property type="entry name" value="At3g25440-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31426">
        <property type="entry name" value="GROUP II INTRON SPLICING FACTOR CRS1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31426:SF2">
        <property type="entry name" value="OS01G0958400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="YhbY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="5">
        <location>
            <begin position="222"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="32"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="373"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="32"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="393"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="441"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0593403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="493" mass="55956" checksum="3105D231F19B8A60" modified="2022-10-12" version="1">MAGPSPTRSLSTSLYSSARYISRALQTRIEPSASRLTASSSSAECDHGERDLSSSSPWESAAAAALVSNEDVLRQRCLLQSRTGTGYMLPRMLLLQSRGYFRQYSGIAFENSRCTELAWSRRGFLRPSPSVSPFVSGGIRFKTRYNKAEQAAKRASKKKKAKAVRLKLRQIRLAKKLRKASMTPEQALLWRIGKCKKKIKLHEEQLKKFELPPLPEPDPDPEILTPEQLHALKKLGYKNKNYVPVGRRGIYGGTIQNMHMHWKKHETVRIDCDNFPKEKIKDMGETLERLSGGTVIDIHQATTIIMWRGRNYKRPKVDIPIMFKNFNKRKALLKSKHEQSIGSLNDQIRKWEKELRAVREDMAREAAERARWLEENPGMEHPDPPAPVATDQSDYDSDEVSDLSDDDDITSMEDLGPEYDSDSDYEYPDSDEDLPNGSVSSDHDRKHSDTSSDMDSSDEWERNVYASGDETESDDDTPTRATLGSLNAARRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4Z6</accession>
    <name>A0A8T0G4Z6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_12G084600</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4Z6"/>
    <dbReference type="OrthoDB" id="1028014at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009742">
        <property type="term" value="P:brassinosteroid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000016">
        <property type="entry name" value="probable serine/threonine-protein kinase At4g35230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000154">
        <property type="entry name" value="probable serine/threonine-protein kinase At4g35230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000069">
        <property type="entry name" value="probable serine/threonine-protein kinase At5g41260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045845">
        <property type="entry name" value="BSK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058209">
        <property type="entry name" value="TPR_BSK1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45863">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE BSK5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45863:SF7">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE BSK5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25575">
        <property type="entry name" value="TPR_BSK1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0519">Myristate</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="61"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0554356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="496" mass="56081" checksum="B092DC70788AA98A" modified="2022-10-12" version="1">MGCSWSMYRKTPAPTPAIPAGSEHANLASENGRRAEPEEVPAFREFPLELLKGATNSFSSDQIVSESGEKAPNFVYKGRLDKNRWIAIKRFPKAAWPDAKGFMDEAWKVGQVRHERLVNLIGYCCEGDERLLVAEYMPNDTLAKHLFHWEKQPMQWAMRLRVALYIAQALDHCANSSLRLYHDLNAYRVLFDQYGDPRLSCFGLMKNSRDGKSYSTNLAYTPPEYLRTGRVTPESVIYSYGTVLLDLLSGKHIPPSHALDLIRGKNMLMLMDSYLEGQFSNDDGTELVRLASRCLQFEPRERPNAKMLVNALTPLQRRTEQIPSHTLMGIQRGDQASPPLPLSPLGEAISRNDLTAVHEILVKTGYKDDEGAENELSFQVWTKQMQDMLNSRKKGDMAFRDKDFKTAIDCYTQFVDVGTMTSPTVFARRSLAHLLSDQAEAALRDAMQAQYVHPEWPTAFYMQAAALAKLGMETDAGDMLKEGAALDLKKQNHYNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5M4</accession>
    <name>A0A8T0G5M4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G073000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5M4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009959">
        <property type="term" value="P:negative gravitropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009639">
        <property type="term" value="P:response to red or far red light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040225">
        <property type="entry name" value="GIL1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31161">
        <property type="entry name" value="PROTEIN GRAVITROPIC IN THE LIGHT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="459"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="531"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="555" mass="61932" checksum="0400B00B62C251CE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G688</accession>
    <name>A0A8T0G688_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G116900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G688"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11124" checksum="8CCAE04AAA224D3E" modified="2022-10-12" version="1">MSVYSALRCSEESCCSQSPCSGALQTLAKPRSPLPHCTALPSSLLLASACSCYATPSSRSRPWPRLHGGPQFIVGSIVVERVRERGEFGLGHWMRAIRCSVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6E0</accession>
    <name>A0A8T0G6E0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G028800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6E0"/>
    <dbReference type="OrthoDB" id="6428749at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052739">
        <property type="entry name" value="FAAH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43372:SF4">
        <property type="entry name" value="FATTY-ACID AMIDE HYDROLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="19"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="313"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="454" mass="48943" checksum="81E88964D121884A" modified="2022-10-12" version="1">MADMVHKRPLAEQIAFPGLVEHYMSRIWQFDGKVNAVVESSACVPEIPFPDNQASPRALEGLPFLVKDNVDVEGFHTVCGGLEFVGNPPADKDSKHVALLRQLGAIPIGKTNVPYLATDVQTFNEVYGSTCNPYNPELSAGGSSGGSAAAVAAGMAAFALGSDWNGSLRIPAAFCGVSSLRASRGRMGCEKGYGIIPPFPTHGSNITGDVLVSGIFAKTVADLKFVMDAVFPLVPPGEKIQDRRVPLPPPESPTVGVWTSFSGVPLDERIRVSMEAIPRRLESTQVTDDGRRLAARLTSGPSLGMARLHKALQAFTQGLNVGNKELTDKFKQTLKEATSAQKEGGDIIDAFLSESGFSALITPVCAILPHEHNYDHHHFHVNGEKVPYWRTLAGYVAPFSVTGNPIVTMPLCTIDGLPLGIQVVGRRQEDEELLRICVLLERQLGPIRDLLQYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8S9</accession>
    <name>A0A8T0G8S9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G124500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8S9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12232" checksum="A3E9E6663D770239" modified="2022-10-12" version="1">MAEDKLSRQGQILERAATTDEKITDVAPEYRGHGATPEEKADENKPWISKGHTLANADDQNRDESGRPQPDIYAQELNKRLGPLNTVKDKIEDGIEAMIEKISGSTNDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9A9</accession>
    <name>A0A8T0G9A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G162000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
            <location evidence="1 12">Extracellular space</location>
            <location evidence="1 12">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9A9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010497">
        <property type="term" value="P:plasmodesmata-mediated intercellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000280">
        <property type="term" value="P:regulation of root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000025">
        <property type="entry name" value="germin-like protein subfamily 2 member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0052">Apoplast</keyword>
    <keyword evidence="7 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 9 12" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035968892" description="Germin-like protein" evidence="12">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="13">
        <location>
            <begin position="59"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0555335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="22650" checksum="CD4758162E8D132B" modified="2022-10-12" version="1">MAKLIVGFVALALLVAVVAAGDAGPINDFCVADLKSALLFNGLACKAPSMVTSDDFAFTGFRAAADTNNPLGIGIIPGFAGVNYPALNTQGLSLAKFNYAKGGLVPPHTHPRASEVITVLKGEVHVGFVDTAGKLFAAKLKTGDFFLFPVGLVHFQLNVGSGHAVTVSVLNAQNPGVQLMASALFGASPEIKDEVLSRAFGIKDDMTKMIKKGFMPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9R8</accession>
    <name>A0A8T0G9R8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GRIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G057100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9R8"/>
    <dbReference type="OrthoDB" id="1926336at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051952">
        <property type="entry name" value="Golgi-autophagy_related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000237">
        <property type="entry name" value="GRIP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23157:SF25">
        <property type="entry name" value="GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01465">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00755">
        <property type="entry name" value="Grip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50913">
        <property type="entry name" value="GRIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRIP" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8366" checksum="58235B4BC6484771" modified="2022-10-12" version="1">MIYVKNVVLKLLETGEVEALLPVIAMLLQFSPDELRRCQEAYRMQAVAEVPFNGAAAVMDAATSAPRPLLSRFTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCH1</accession>
    <name>A0A8T0GCH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL13c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L13, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">CL13</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G132600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCH1"/>
    <dbReference type="OrthoDB" id="274622at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_uL13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00068945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00077140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00082726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="33037" checksum="F3FA1534EB2933B6" modified="2022-10-12" version="1">MFRTHNGFKAPSLIQESERRRLKLRVCSQFCREFVSCEAWKSSCRDWRAGDWSEEMASAAAASAMAAQFASMTVSSPASGSSKSLSSSFTGNAALVSLRRRVVVPSLRPRNVAVQAKGGFIPAEHRWMYEGIEKMGPDVWNTTYYPKADDHKNVEKKWYIVDAADKRLGRLASTIAIHIRGKDVPEFTPSIDMGAYVVVINAEKVGVTGKKRAQKIYRRHSGRPGGMTEETFDNLQKRIPERIVEHAVRGMLPKGRLGRRLFTHLKVYKGSEHPHIAQQPAPLPITDKRIEMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDN7</accession>
    <name>A0A8T0GDN7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G123400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDN7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="318" mass="35886" checksum="C40B83683056CC45" modified="2022-10-12" version="1">MALLGDGEATYESSSYSRFREVPKLLMDYGIVHHSFRGLYEFKKICKDFFVDLMEGDLKGDMEGKSPYLGFTRVGLSDISSIDEIRLQGDVPKMTILYDSGEEVLIVKFMVGVTHETCAGLLQMSFIEAVRARVGHIYSMYSLKSARFRSAQRMKEADDSFKPRTRNNESDWPSIVFEVGVSERLTELSQDARYWLESSPQQQTRIVILASVNKTAGTMIIERWEAEAPTLQAAAPTLQAARNVSNSNPYSRQVVPICMQTLTLERDQHYAGPPLSIPATLVFDVLPFSHGPAWGPSDFKITVHMLNMLNEMFWDGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE90</accession>
    <name>A0A8T0GE90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cation/H+ exchanger transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G094700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Na(+)(in) + H(+)(out) = Na(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE90"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF197">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="423"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="12">
        <location>
            <begin position="46"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0557005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="567" mass="62924" checksum="B599EF8FC0E90DE8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGJ8</accession>
    <name>A0A8T0GGJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G028600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219:SF14">
        <property type="entry name" value="PROTEIN COFACTOR ASSEMBLY OF COMPLEX C SUBUNIT B CCB3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33219">
        <property type="entry name" value="YLMG HOMOLOG PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="CCB3_YggT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="136"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="200"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="228" mass="24484" checksum="EC6FDC452FDF12C3" modified="2022-10-12" version="1">MASTALLRRLPSPALSSPQTFHPLRPSRAMRVLAAPRSHLSLQTPSSSTSTHLSPATRSPKPDLSLHSQTDQDARELNSEDNSTQHLKHLALAIAMACPALLLAPHEASAATSLAMESGEILRLSAAELDPSTAKLAITILGPLFAAFNLMFIIRIVMSWYPQIPVGKFPFSIAYAPTEPVLGPTRRLIPPVGGVDVAPVIWVALMSFLNEILLGQQGLLVLLSQQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHE2</accession>
    <name>A0A8T0GHE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G060200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="1351"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="996"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1195"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1051"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1238"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1591" mass="178155" checksum="44E0EC71C76A1321" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHL1</accession>
    <name>A0A8T0GHL1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G003600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035745594" description="Secreted protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6597" checksum="D759982397F4D5B2" modified="2022-10-12" version="1">MWVGRTGHRATAWPPESPFCLCLCLCLCLHLACSRLPPATHDIIPVDLCCSLLRFTPPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI21</accession>
    <name>A0A8T0GI21_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G012200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI21"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035723539" description="Secreted protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="10333" checksum="0748B0BAFC44C33D" modified="2022-10-12" version="1">MRRNWHILDLFLVKFFVIVEVPGTLELICCMHYSWVYVNDPITDQRQNDSIVQLTCFSLKIFELSSSKHSLLIRRFCLGWAQRLAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIM2</accession>
    <name>A0A8T0GIM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G172500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31150">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31150:SF32">
        <property type="entry name" value="RING_U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="355"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="87"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="169"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="271"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="468"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="52140" checksum="F9CFBBB5A6F3F839" modified="2022-10-12" version="1">MQQLAIRFQSREVKSGTTAAIPVPDLWDGGINYTEKEKERACTQAAKTGSLCCVAARPHGTSENNHNWSTAGDKPRWHPNEGYVPPFSSSHLDRSQGEEYLGTSSRTFPTHRRSLSSSGRGSRSWRRVDGARLYNHYRTPSGSLYGGSPNNFIWNPLASSSHRIADSMTAESELADSPSTMTPSSKAEHFFTRPPAFPNKSEIISSPFVSTMKPPTHSESVPSSSHVNDSLLSKPSFLMPSNHSRREQYEGRFPPAGPGRVSSLDGRFSFHRSNSSRSTSSAGGSSDWSSYHGLMEMGPDARQEWLRITNATSPSDYSWGFNREGYDRGSGQMCMEKITASGSRSASPSPRPESCSICSRSLTQRSPWASSRVMGFHECNVVGVLVCGHTYHTECLEQITPDSSRQDPACPRCSSDKVALKKPVASAPTAVKAGTVRGSSFMSRPSSRNKLSRIGVLDDAENLGKPRFSSSSPDEPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GL38</accession>
    <name>A0A8T0GL38_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BEACH-type PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G092000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GL38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050865">
        <property type="entry name" value="BEACH_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023362">
        <property type="entry name" value="PH-BEACH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743:SF157">
        <property type="entry name" value="BEACH DOMAIN-CONTAINING PROTEIN C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13743">
        <property type="entry name" value="BEIGE/BEACH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14844">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51783">
        <property type="entry name" value="PH_BEACH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BEACH-type PH" evidence="2">
        <location>
            <begin position="114"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="237" mass="25975" checksum="2A8811CE94A4776E" modified="2022-10-12" version="1">MRKRLKQNYKGAEHQIPMKGYEQSQRTSSDGELPVASAMAKLITVNSTGNDTGEEASRSEDEIEEAGSYSRKEESNSTTERTHSGIAQTQSSNTAPAPTSPPPSPVPAAPSTPEAKEVLILEMPGVLIQPLKLRGGMFQVTTRRISFMLDDRVQMNETGVAVLIGADGVSEVEAGGEVEGKRKQRKDGSKDRLWPLSLLKEIYTRRYALRKSALELFMADRSNCLFNFGTTGARKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN15</accession>
    <name>A0A8T0GN15_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G118600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="89"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="229"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="173"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0559614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="56811" checksum="07A37267794D65D6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN46</accession>
    <name>A0A8T0GN46_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G027200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NADP(+) = (2R)-3-phospho-glyceroyl phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Tetramer of either four A chains (GAPDH 2) or two A and two B chains (GAPDH 1).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN46"/>
    <dbReference type="OrthoDB" id="1152826at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047100">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000002">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="9">
        <location>
            <begin position="70"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00063826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0560971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="405" mass="43135" checksum="A0B44CDE58C4DB4B" modified="2022-10-12" version="1">MAATAFTAASAPSCAVKAAGSKGFSEFSGIKNTNAVTFGKRSDDLASIVAAQSAVSASSGATRAVTEAKIRVAINGFGRIGRNFVRCWHGRKDSPLEIVVINDTGGVKQASHLLKYDSMLGTFNADVKVDGNDGISIDGKTIKVVSDRNPLNLPWGEMNIDLVIEGTGVFVDEAGAGKHLQAGAKKVLITAPGKGAIPTYVVGVNEQDYTHEDKIISNASCTTNCLAPFVKVLDEKFGIIKGTMTTTHSYTGDQRLLDASHRDLRRARAAALNIVPTSTGAAKAVALVLPRLKGKINGIALRVPTPNVSVVDLVVQVEKKTFAEEVNQAFRDACETPQLKGILAVCDEPLVSVDFRCTDVSSTVDSSLTMVMGDDYVKVVAWYDNEWGYSQRVVDLANLVAEKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP91</accession>
    <name>A0A8T0GP91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G170400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="342" mass="39212" checksum="716DFF4D10BE63B3" modified="2022-10-12" version="1">MVQERASSKTRRPSELGSLLPLPCLLLPLLRIWSLLVVIFRSSEDMYHESAPVDKLKDATISISELIVDREAPPAATQPILVGKVHALPLHPMRLQHQLLILRRQVLLAKPILQTHPKPTRGMRAQQRLNKRRILNLLPNLLRSINSSHPHLVLQILRRQPMPGLQLLPLPSLHRRLTIRHSRLRSNPRRSPRYSLILLRRHCLPLHRFLLPLPLMQTLRQRLQPHLLHPLLILLHSVLPQLLVRHRHLLLQLPHLPIHLHLHLNLHLHHHLILHLHHHLQSPNQNSITLNSITLNSLFATKIPATECHKVIKTRSPMCESHGGNPASKPGEEGDGCTVQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPS8</accession>
    <name>A0A8T0GPS8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lachrymatory factor synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G077600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd07821">
        <property type="entry name" value="PYR_PYL_RCAR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053249">
        <property type="entry name" value="LFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33789:SF5">
        <property type="entry name" value="BET V I_MAJOR LATEX PROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33789">
        <property type="entry name" value="LACHRYMATORY-FACTOR SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="188" mass="20785" checksum="BBDEFBF52F40A14F" modified="2022-10-12" version="1">MLSYEAFSIIPTGIPTIIPASPHDSMLSSLVRRLGSMASTNISAADDHWHGAIDVVIAAPVEKVWEIASDWLKFPRCCSVECSEGENGVPGCVRKVKAYNSNFWVAEKLTRIDHSCRIISYDLVGGNTGIDVGYRASFQAVAEGENKTRVVWPFMFSPEQVCVESWTAIVKKKVKAHIKELEELAQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRH9</accession>
    <name>A0A8T0GRH9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G071100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052426">
        <property type="entry name" value="Plant_dev_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45801">
        <property type="entry name" value="OS07G0101800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45801:SF107">
        <property type="entry name" value="TRANSCRIPTIONAL REGULATOR SUPERMAN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="16525" checksum="AE9371AB277321C1" modified="2022-10-12" version="1">MPEAIGIDEVAVRHLSRKSARSFPCNFCDREFRNAQALGGHMNVHRREKNLAKDLMQLRNHGGEGEEPPSSNSPPVLHAGIAQDDVKIDTVIVHGDSVLPGSSTSSSSPPSQASTVSFANSLGYGVRSLVSCESVDRPTAVDLELRLGRHGPDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRM8</accession>
    <name>A0A8T0GRM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-3' exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G172700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033567">
        <property type="term" value="P:DNA replication, Okazaki fragment processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09859">
        <property type="entry name" value="PIN_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038969">
        <property type="entry name" value="FEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646:SF4">
        <property type="entry name" value="5'-3' EXONUCLEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42646">
        <property type="entry name" value="FLAP ENDONUCLEASE XNI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5'-3' exonuclease" evidence="4">
        <location>
            <begin position="254"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0560338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="539" mass="59954" checksum="A5A98883CE4671E7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSQ2</accession>
    <name>A0A8T0GSQ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G105900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSQ2"/>
    <dbReference type="OrthoDB" id="1875375at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11915" checksum="D0DDC8292934FEFE" modified="2022-10-12" version="1">MVNVPKTKKSFCPGKACKKHTLHKVTQYKTGKASLYAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLQCQACKHVTQHPIKRCKHFEIGGDKKGKGTTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT16</accession>
    <name>A0A8T0GT16_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G086000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the saccharopine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT16"/>
    <dbReference type="OrthoDB" id="10268090at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051276">
        <property type="entry name" value="Saccharopine_DH-like_oxidrdct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12286:SF5">
        <property type="entry name" value="SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="48490" checksum="DB7A788734CA29FF" modified="2022-10-12" version="1">MAEELVDIVILGASGFTGKYVLRELLKFANPPNSAPRKIAIAGRSRKKLAAALTWASSDPNLSSSVPIFEADVNSVQSLVTLCKKTKVLVSCVGPYRKYGRPVVEACVEAGVDYLDITGEPEFMEEMEHLYHEKAMQSGSLVVSACGYDSIPAEFGVIYNTQQWEEPSVANTVDSYLVLETKGKRIKGNIGTWESLVLGVANEANLQKLRKSRPRRSRPQIPGGSSKRPGLIHWEENAGGWAVRLPSADATVVRRTHATMVDNPNGLPKAGGEPSDEKPWASIKPVHYGCYVIQKSFVGIIGMFILGFILVVFTQFKAGQKLLVQYPELFSLGTFHKEGPSEEEIEQAYFRMIYVGRGYSDSAKISSGSKPDKEIVTRISGPEIGYVTTPIVLIQAALIMLDERRSLPKGGVLTPGVVFGGTDYIQRLQQNGMSFDVISTKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT52</accession>
    <name>A0A8T0GT52_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G057300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT52"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9494" checksum="C1328B69E76AC991" modified="2022-10-12" version="1">MGKWGPCYLPEKKPDFMSISFHDGSGHGIYQRISEGNFLCQAGLIQAVHESCAGRQFVAPVVICITSTSLAAFGSLFQSLVKTRRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTR3</accession>
    <name>A0A8T0GTR3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G091000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035790161" evidence="1">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5858" checksum="E7FC8D2CDE4C6958" modified="2022-10-12" version="1">MILHLHLILLNLSSTWKGGRHMNLFEPVEDRDTALIFSGLALPNWWHIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUS2</accession>
    <name>A0A8T0GUS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G122100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11429" checksum="E57AF07021DBDDE4" modified="2022-10-12" version="1">MMLRAVRNLPVNKDIRKPFTTNASGEHQRTKCICICKSSPSQVLNALWLTVPPPQSSPPSPAIDSNFGLSPFCTGLQSNLQDSLRMECNEKRRTLDSSEAQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUW7</accession>
    <name>A0A8T0GUW7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7705 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G038700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUW7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056122">
        <property type="entry name" value="DUF7705"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33916">
        <property type="entry name" value="EXPANSIN-LIKE EG45 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33916:SF1">
        <property type="entry name" value="EXPANSIN-LIKE EG45 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24804">
        <property type="entry name" value="DUF7705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035831444" description="DUF7705 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7705" evidence="2">
        <location>
            <begin position="43"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="58826" checksum="9FC6001DF24AC413" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVM8</accession>
    <name>A0A8T0GVM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G027300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NADP(+) = (2R)-3-phospho-glyceroyl phosphate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Tetramer of either four A chains (GAPDH 2) or two A and two B chains (GAPDH 1).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047100">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000002">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="9">
        <location>
            <begin position="71"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00052787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00063826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0560972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="406" mass="43074" checksum="0F10FC25CCFAA318" modified="2022-10-12" version="1">MASASMTAAAAPSASAAKIAGTKGFSEFSGIKSANAVTFGKRSDDLASIVAAQSAVSASSGATRAVTEAKIRVAINGFGRIGRNFVRCWHGRKDSPLEIVVINDTGGVKQASHLLKYDSMLGTFDADVKVDGNDGISIDGKTIKVVSDRNPLNLPWGDMNIDLVIEGTGVFVDEAGAGKHLQAGAKKVLITAPGKGPIPTYVVGVNEQDYSHDDKIISNASCTTNCLAPFVKVLDEKFGIIKGTMTTTHSYTGDQRLLDASHRDLRRARAAALNIVPTSTGAAKAVALVLPKLKGKINGIALRVPTPNVSVVDLVVQVEKKTFAEEVNQAFRDACETPQLKGVLAVCDEPLVSVDFRCTDVSSTVDSSLTMVMGDDYVKVVAWYDNEWGYSQRVVDLANLVAEKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWD3</accession>
    <name>A0A8T0GWD3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G012500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="148" mass="16739" checksum="3811E7CFFFD25C74" modified="2022-10-12" version="1">MYNVCAAGDEPIHRMLVKQCKCRVAVLSERWLPESVLTHLRANPSCEDRVSEALAPGRGDENFGRCFHVQACCGGTSEFLSCEDNAVVRQSRRYPVDPVWFMSFRVSVSRTIHDLTSEIFAKSVVEVLKGGTEVDVRPQQCQVELFMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWN3</accession>
    <name>A0A8T0GWN3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G031700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="9114" checksum="DF3699FA8071B92C" modified="2022-10-12" version="1">MKHISSRGGKGWGEGSSGIHEHWSYELSRIRGRRPRSRSESKRKLSYWLKPHRIHPSWSPLVSRLITSSKYPKQSFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWV4</accession>
    <name>A0A8T0GWV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G037200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="7042" checksum="36266C212ED6CD04" modified="2022-10-12" version="1">MTVTLEDSRQTSRHCIGDNDCERAEIGRFRVSPLYHQIHRSPLAHLNVHDSFVMTHQDVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXF1</accession>
    <name>A0A8T0GXF1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G145300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXF1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000394">
        <property type="entry name" value="MYB transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000001">
        <property type="entry name" value="MYB-related transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015495">
        <property type="entry name" value="Myb_TF_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47999:SF124">
        <property type="entry name" value="MYB TRANSCRIPTION FACTOR 42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47999">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYB8-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="11"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="14"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="64"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="64"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="193"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0562428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="34675" checksum="3EE0677C9A66231F" modified="2022-10-12" version="1">MGRAPGARVSEGGLNKGPWTEEEDAILAAFIKANGEGNWRTLPKRAGLQRCRKSCRLRWMNYLRPDLKRGNFTPDEDDLIIKLHSLLGNRWSMIAGRIPGRTDNEIKNYWNSRLRRKLRSADSSDVSQFLEATPLSFDSPKPEPASSTQSDQTPSITTGLASNYEPTFPSYADALPDSSIFPEYDRFHGTPSAEETLSDSSSDGTCNLEDQSCDHYYSAWTPALDEVTEDLTQSVSVKRELCAYSPESVLFGQQGNSIPDDDFSNIDFCSFMAGFSDSFGETNVNKLLLSPVQRNLVTSSWPSCYPTDGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY67</accession>
    <name>A0A8T0GY67_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G073100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY67"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17490" checksum="E88918A8F74C4208" modified="2022-10-12" version="1">MWRLPPSTQSESPMTYPQPFSHDRVFFVSVFTLRIVAPMGGDEAVFMQFDEQYYMKNRLLIHLRSAMRIETVSSQRRPPDRGPRSSPTIAPARLAPQVVKVVVLINSAQLCACSRLLGGVLSRPADGVWTGALQSIECPTLRASPPPPTQMEFWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYV7</accession>
    <name>A0A8T0GYV7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G047200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="35" mass="3926" checksum="E7429621CA6F2614" modified="2022-10-12" version="1">MVSLLGGFDMLLLIPLPIESGSFLMDLLMRYGLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0D5</accession>
    <name>A0A8T0H0D5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G065300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0D5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054502">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051358">
        <property type="entry name" value="TF_AMS/ICE1/BHLH6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31945:SF11">
        <property type="entry name" value="TRANSCRIPTION FACTOR ABORTED MICROSPORES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31945">
        <property type="entry name" value="TRANSCRIPTION FACTOR SCREAM2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22754">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="169"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="263" mass="29266" checksum="D539032A7A1F3EC2" modified="2022-10-12" version="1">MGAVQHAAEDRESMLDVDIDFEGSSSSTSSGSDVEGHVFGAIQSSRGLQRSVEVAPSFSKRTYGVNQVAYESTSMERMRKCAKLDEQLDGLRALLPHSTRRRERNDPSVVMDAYRYIVALQQEVEDLSAELLECEADSCDQESTFKLHRSKISYQQPLVEVMKRDGVMEVRIVCPTRPGLLVDVMEAVEARGLTITQARIACYKDNNNFKYLSLEIEESAIMALSTEGGSEEADSEEDLDTVKAMLVDAICEGNLRYIDSDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0F8</accession>
    <name>A0A8T0H0F8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G201900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0F8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050464">
        <property type="entry name" value="Zeta_carotene_desat/Oxidored"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923:SF46">
        <property type="entry name" value="AMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42923">
        <property type="entry name" value="PROTOPORPHYRINOGEN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amine oxidase" evidence="1">
        <location>
            <begin position="145"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="410" mass="44563" checksum="1847DF3EBCE14C88" modified="2022-10-12" version="1">MSSFYSPEGIQVEAPVFNTLPRLPTPLGSFLYTSSYFRAWLQKHDKAGNWSLALGSRFLMNLKNDEETYASYDAMSARELFRKAGVSAKLYREFLQPIVLVTLFAPGEQLSGEDFVDCPCGSSWSVVLLRSVAEVIFKPWLELINSQGCRVLGNNRVVDVIHDDESNKITGIVAMDGSGERTVYDADVVVFAVGVQAMQRIVASSPALAGRPEFATISNLGTVDVLATRLWLDRRVPLKNPSNVLAGFEPTTGATVFDLNALQNEFADEPGSVFEVDFYHANQLLPLTDDAVIKKVIDSSVLRFKGAVTLFGPGSHQHMPSTTTSFWNVFMSGDWLQQGPGAHGARGLSQEKASVTGLLAANAAASSLGLKSQVEVLPVEEDEAHIAARKSAAQTLRQAARAFGLRSPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2S0</accession>
    <name>A0A8T0H2S0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G107600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2S0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="16351" checksum="44D54713D57BC40C" modified="2022-10-12" version="1" fragment="single">MQFRSCCVDATWTINSRLEESPEAVISSRLTFGPQVRSLLRTYQCHVDCSDKKSTPSLCSVGFPSTTPSRSSKARGHMVHILWIRGQGLLASPFKIHKLNQPLYHASPTHPHRVHCFERIMDLLTRTHADFASILACIRGCSTSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H371</accession>
    <name>A0A8T0H371_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Polygalacturonase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G069700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Cell wall</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H371"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004650">
        <property type="term" value="F:polygalacturonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000743">
        <property type="entry name" value="Glyco_hydro_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31375">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00295">
        <property type="entry name" value="Glyco_hydro_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00502">
        <property type="entry name" value="POLYGALACTURONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <feature type="active site" evidence="8">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0566521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="443" mass="46423" checksum="F0B1691FEE8DAF23" modified="2022-10-12" version="1">MAEWMRGRRRGVVGVDGRDLFVLVLAVTVCVATRTSEAAFTNFAKTSRSNNGITTMSSGGQSSSDAVFNIRTFGAHGNGASDDTKAFLAAWAKACKSGGVATVLVPSGYSFVLGSNTQFVGKGCTSKIVVQVDGNILGPGDKSKWQNAKSASAAWMQFTDCKDVTIQGTGTLDARGQSFWPSGNGGPIGIRFLRGTNIAVLGVTIKNTPQVSVKLNFCNGGLIQGVSIINPADSPNTDGIHLQTNVYNVQILDCIIKTGDDCISIGTGTHNVIIRNILCGPGHGISIGSLGNKGLLACVSDIDISQVTFVGTLAGCRIKTCAGGKGKAARISYRDIKVEGVKYPIHIDQYYCGKGTKSENVILDQIEFYNIKGTAAKGQIPPVYLDCAAPGCTNVRLQNVQIDYAPGAYCSNSYGTYGGVMHPAGCLQYKLNSQSRSAPGCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3P7</accession>
    <name>A0A8T0H3P7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha 1,4-glycosyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G081100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3P7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007652">
        <property type="entry name" value="A1-4-GlycosylTfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007577">
        <property type="entry name" value="GlycoTrfase_DXD_sugar-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044789">
        <property type="entry name" value="Put_A1-4-GlycosylTfrase_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46781">
        <property type="entry name" value="ALPHA 1,4-GLYCOSYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46781:SF5">
        <property type="entry name" value="ALPHA 1,4-GLYCOSYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04572">
        <property type="entry name" value="Gb3_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04488">
        <property type="entry name" value="Gly_transf_sug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha 1,4-glycosyltransferase" evidence="3">
        <location>
            <begin position="439"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="570" mass="64762" checksum="E857FD230781BAE9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3Q2</accession>
    <name>A0A8T0H3Q2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Pyruvate kinase</fullName>
            <ecNumber evidence="4 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_8G187800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 14"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3Q2"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000004">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000006">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="30"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="16">
        <location>
            <begin position="395"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0565407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="526" mass="57291" checksum="9514E1A4537B741E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3Y8</accession>
    <name>A0A8T0H3Y8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G141500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000003">
        <property type="entry name" value="ABC transporter C family member 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000169">
        <property type="entry name" value="ABC transporter C family member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000002">
        <property type="entry name" value="ABC transporter C family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000508">
        <property type="entry name" value="ABC transporter C family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF189">
        <property type="entry name" value="ABC TRANSPORTER C FAMILY MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="731"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="772"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="955"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="106"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="424"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="12">
        <location>
            <begin position="733"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="11">
        <location>
            <begin position="1052"/>
            <end position="1284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0564808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1295" mass="145347" checksum="5951A9807A299BAE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H453</accession>
    <name>A0A8T0H453_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Transcription elongation factor 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G165200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 11">Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ELOF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H453"/>
    <dbReference type="OrthoDB" id="445983at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008023">
        <property type="term" value="C:transcription elongation factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.190:FF:000001">
        <property type="entry name" value="Transcription elongation factor 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007808">
        <property type="entry name" value="Elf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038567">
        <property type="entry name" value="T_Elf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20934:SF0">
        <property type="entry name" value="TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05129">
        <property type="entry name" value="Zn_ribbon_Elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="8 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0565109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9595" checksum="8233C2777A26BA51" modified="2022-10-12" version="1">MGKRKSAAKPAPRRGQEKLATVFSCPFCNHDNSVECRMDRKNQIGEASCRICLEKFSTPIDSLSDPIDVYSDWIDECERINGGAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H492</accession>
    <name>A0A8T0H492_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G174000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H492"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF24">
        <property type="entry name" value="ABC1 ATYPICAL KINASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="1">
        <location>
            <begin position="322"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="648" mass="72379" checksum="1EAB9DC69414C1CC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4B4</accession>
    <name>A0A8T0H4B4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="12">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G170000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="12"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4B4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000444">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF155">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="139"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0565169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="436" mass="48419" checksum="91D0A5310BEFCA8D" modified="2022-10-12" version="1">MVTLHTLAIPIAPPLLRRRCHPSTTNTCIATSISGSPTQLILFSPHLTILPHVCFISKHRLRTSSCHGRQLERLITGSPVDGFVATMRKSSLPLHSFKPHSASTEPVIARDDELHKRLHELLLQHFGYTSFRGQQLEAIETVLQGKDCFCLMPTGGGKSLCYELPALVKPGIVLVVSPLIALMVDQVSGLKKLKIAAEYLSSTQQASVKTKIYDELDSGRPSLRLLYVTPELIDTGGFMVKLRKLHGRGLLTLIAIDEAHCISSWGHDFRPSYRKLSSLRSSLPGVPVLALTATAAKKVRDDVVKSLGLHQPRILVSSFNRPNIYYEVRYKNVLKDAYKDLRDLLSSAPDDCAIVYCHSKNDCDDIGARLARDGLACRGILSRINIVSWRTRGQSARSSSTRLAIWESWDCCSNRRIWVGGLYVITLHCNSSFVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAH2</accession>
    <name>A0A8T0HAH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lon protease homolog 2, peroxisomal</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_7G130800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Peroxisome matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9 12 13">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAH2"/>
    <dbReference type="OrthoDB" id="2411602at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005782">
        <property type="term" value="C:peroxisomal matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000002">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000005">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000019">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000651">
        <property type="entry name" value="Lon protease homolog 2, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03121">
        <property type="entry name" value="lonp2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027501">
        <property type="entry name" value="Lonp2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="ATP DEPENDENT LON PROTEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="2 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="16">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="15">
        <location>
            <begin position="706"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="72"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="631"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Microbody targeting signal" evidence="8">
        <location>
            <begin position="899"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="638"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="797"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 10 12">
        <location>
            <position position="840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="418"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0567378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="901" mass="99257" checksum="03BDA9CC81382683" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAS7</accession>
    <name>A0A8T0HAS7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G138600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAS7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14620" checksum="8BBAC7E017E82DC7" modified="2022-10-12" version="1">MPTTAPWSQKHLEAATIKNEPPIIVQPWNMPTSPPNNPFSYSTRLHQYHPKTPHHAPEQATSHHTLAIYHPTWHDHIHSAQQFHECRIRALNWAPCKRVHLHQTHSLRLITCINHEKSVITHAGEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBZ6</accession>
    <name>A0A8T0HBZ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G056600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14709" checksum="3434A37EC6C6972D" modified="2022-10-12" version="1">MIELTFHWLIPLSSNDPILFFVVLIALVSYVLAPSVDTLVPSFLNAQTASFFVVLIVSCVLAPSVEALVPSFFVVLIALVSSVLAPSADALLPSFLNAQIPSFVDIQYPSTFEPSTFETPSSTFEINIKDYISYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDK3</accession>
    <name>A0A8T0HDK3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CHCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G101900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDK3"/>
    <dbReference type="OrthoDB" id="1106148at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055304">
        <property type="entry name" value="CHCHD2/10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523:SF2">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13523">
        <property type="entry name" value="COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="78"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="15222" checksum="F4E9998E7E971B0F" modified="2022-10-12" version="1">MPRSRSSRASRPVMRPAPAPAPARQTPPAAPPAQYQQQQRRAGIGSTIADGMAFGGGSAVAHRAVDSLMGPRTVTHEAAQNPTAAPTTAAQPQGFDACENQAKAFKDCLSFNVDDIGKCQFYVDMLNECRRSGGGGAPQQAPNWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFS2</accession>
    <name>A0A8T0HFS2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">KC19_6G052300</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="23 24" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="23 24">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000358">
        <property type="entry name" value="Putative leucine-rich repeat receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="294"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="22">
        <location>
            <begin position="606"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="901"/>
            <end position="921"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="21">
        <location>
            <begin position="940"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="634"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0568929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="980" mass="108388" checksum="D6BDEBE3D9144379" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH00</accession>
    <name>A0A8T0HH00_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G089200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH00"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16545" checksum="A0FCB69D0EED1B7E" modified="2022-10-12" version="1">MSSLVFSNTFKAGPLYFGVSDLKMHITETKSRYVQNLVGRQSMETTMYERSPINHLDKLTCSIILFHGQQDKVIRPTQSRLIYEAVNKKGITVALVEYGGEQHGFLMAEKIRNTLEQEMVFFARLVGGFQVADSIIPIKVDYFDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH32</accession>
    <name>A0A8T0HH32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G092800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056813">
        <property type="entry name" value="GIL1_IRKI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24994">
        <property type="entry name" value="GIL1_IRKI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="233"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="569"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="609"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="960"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1035"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="635"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="663"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="960"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1037"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1061"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1086"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1108" mass="124033" checksum="C6D0408301BC6758" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIW1</accession>
    <name>A0A8T0HIW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein mS23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G138700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrion-specific ribosomal protein mS23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIW1"/>
    <dbReference type="OrthoDB" id="543108at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd23701">
        <property type="entry name" value="At1g26750"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059242">
        <property type="entry name" value="mS23_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35693">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35693:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00035137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="21178" checksum="366A4C4AE790772A" modified="2022-10-12" version="1">MSFMKGDLLSKTRKLMKGGIIARPRWLDAVMRIPPEPKKTRCKKAPKIVLPEDRLVESYYARHPEAKFTPFELNSFDPPPARKFAWRQLELMNHGYPRDIARDMVEVEFAEAEKAAEEAFRAERRRAIMEGREPPAPKKSKIEEIQEEEWEYLSQGLAAIGSQGRKAGEKLPGSERPPRVSSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJR6</accession>
    <name>A0A8T0HJR6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G205100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJR6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="53383" checksum="0FD07D6F3CAA6698" modified="2022-10-12" version="1">MDRALEESDARGLRDLEAFVNVSEHNSVPCFYSCTIHTHHTPATSRESLRFHVSLARRDSLAIESDCHNLDKNRASYSGVGAVNLLEAIRILVACPTLTYTQYVDSRLWASSSKKFDVPHRFNEDLMSEVFSLLKSSPSLSWFHFFNSVGSDVSLYCKHLQTLVCENPRLETLTVVSTSGPNLVVLAKALAVCLSRNTVLNSFTLKNLADNYELSRESLEILLSPFTSSSPSEANADLKELALYSGYDPSKYSDVDVDVMANLVCRNTTLKKLDLHFSKFRSCLKDGKSSWREFCRALEVNQTLEELSCPCEVAAMRELLVPFVLDRYGRQPNTTLSTLRLSVSIEGHCRRVEVLVNNFVIVLRDLASALQRNTTLKHVQFIFQRNMYGDYKRYDTKYSTYKVLCQAEPQIQEILRMMIDNELRVNTSLESLEVGHWSLLRVGTEWQTSYRGPCLRKAKEYYVKVKVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK02</accession>
    <name>A0A8T0HK02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G213000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035755971" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6548" checksum="88521A58082099D3" modified="2022-10-12" version="1">MHACILTLLTLLWGFLDTVCVGVSDLFHHLVGVSVLQWNGMHGCSCSAVGFWNFRFLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKW8</accession>
    <name>A0A8T0HKW8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG011800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19401" checksum="6CDCDB1F0742FAE9" modified="2022-10-12" version="1">MLFLHFHVGLWSKMPLGELKPLLTHILPAGVMERLSFVYSRSDLIDRENFPWSYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRRTPNCMCYIPWPFQGHLNFPNDDGVIPNIATDILPLVYPLHKFGSVPEYMAQACRPGQVHWAIEAARNFGRARVDWTEVCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLL2</accession>
    <name>A0A8T0HLL2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG032900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12528" checksum="D9B05571BEC8EB83" modified="2022-10-12" version="1">MWTTMEATMTDGEGNVKEELRVRVGPRHQMRDCGRGTASPNGQPNVPLAYPRPTTPTLPAQTLNWIPRQWDLVRRRRPSHTSRKLAGLTFFAQGMLCLPASSLCLRDNREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM85</accession>
    <name>A0A8T0HM85_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG052400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="10476" checksum="4DC4230A8403E22E" modified="2022-10-12" version="1">MPVISMHSSSTYAWQQGPQALGHLPCSLALAFPEMHGIYPDHECPGLAQVQLRRAAQVMLRSSRREYLSLILVIPRPHQQKVSSHLCLMSLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNL6</accession>
    <name>A0A8T0HNL6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Maltose excess protein 1-like, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG094300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005363">
        <property type="term" value="F:maltose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034628">
        <property type="entry name" value="MEX1/MEX1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34809">
        <property type="entry name" value="MALTOSE EXCESS PROTEIN 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34809:SF1">
        <property type="entry name" value="MALTOSE EXCESS PROTEIN 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="417" mass="45206" checksum="2645CDBF761276A3" modified="2022-10-12" version="1">MTVAHAIPSLLHRNVSPAHSAAGMRTVVGYMRSHVHARAVSGGTGKELLDRWCVAPMGSGLVERKRAWVAVPRALSEDGSLEFSKVSDEVAESPSAEYKHWDGMTARLAESATVAFLLLQLPQIILNTQNLMSGNNVALTAIPWMGQLTGLLGNLSLLSYFAGKRERGATVVQALGVLSTGVVITQLALGGAMPYPIYLGTAAVVVVGLLFNWLSYFNKLSLTLWQLWLDSVTVGGLTFLPQIMWSTFVPYISPSILPGTSFGTIALLLVILNRLNKLPPAALKFYTGLSAWTATLLFMWGPVAQAWSNYLNPSNIEGLSVLTILLAMTGNGLLLPRALFTRDLMWFTGSSWGTLLQGWGILLTMFIFQVVNDVLFYGVSVVLALYLGLMFVNDSKAYSLKNPIKPLIELVTGSRST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ95</accession>
    <name>A0A8T0HQ95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG147500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="16035" checksum="288544FA3DB19254" modified="2022-10-12" version="1">MALHSASSFVSTSRFKRGYMVKLVRCAMQCSPNMKGAACAFIVSVTPFVQPWNKEFPSATKHMRTPRARSKKIQLKTKLVSDAAPLLRSLALAKQQYPPPSHYVPSILSHILREHSQIRSNTNLQVPSYAMQVPCGGLHVSTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR53</accession>
    <name>A0A8T0HR53_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG158800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR53"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="4">
        <location>
            <begin position="30"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0573215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12125" checksum="C334B7A19FE9ED41" modified="2022-10-12" version="1">MEAKLVSSVPPEKRPRSYGAGSGIDSDSERVRVTVRVRPPTRAEQKEEDGPPFIFLDTDKNTVILRRKGSFVDFTEFQFDAVLPSTALQVDVYNIAARTIVLVSLTLTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS42</accession>
    <name>A0A8T0HS42_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG212000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="ENDONUCLEASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607:SF2">
        <property type="entry name" value="ENDONUCLEASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="His-Me finger endonucleases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0573820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="7844" checksum="F56C14C3BA8A9AA2" modified="2022-10-12" version="1">MTPRCLIPANREATADTATDTNTWRPPTQVRGDIARAVFYMAVRYGIEQPSGSVNLQLSDSPSVGMLSFSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSX4</accession>
    <name>A0A8T0HSX4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG233300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSX4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="229" mass="26573" checksum="71A26C915321906D" modified="2022-10-12" version="1">MTNYSSGVQKSRMMVTPRQSDAVESSMGSMWAHARDVPPVHTNRYNMPSGEYWEHMQAYVYDRGAKTFPSHVEWRKQCPELKAHFIRGIRKIYPGNWESKGVLEAVGKSIREKRARLRAQFKVYRDPKKVGRPNGCTFESWNKIWQDIEDPKKKEFAAVMSHKVRERLQSGQRRFSHRCGRKGYDGIVVKFVSYSTLLQCIVIVKYTGLACCLHFAHTKHETVQKCSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUK4</accession>
    <name>A0A8T0HUK4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG286300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12007" checksum="B14133B6D5DDA29B" modified="2022-10-12" version="1">MRSDGAMKVGVQNLVALGGCGAVMPPCRPLAEATVRVQNRDFKGGVEKESTRPCNEPVPVQCEHSPSSILAGKRFGRENDRDDMTDMNSIWGKTKGLKLLTELEEPHSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUP2</accession>
    <name>A0A8T0HUP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG289800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.30:FF:000001">
        <property type="entry name" value="60S ribosomal protein L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00481">
        <property type="entry name" value="Ribosomal_eL30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000231">
        <property type="entry name" value="Ribosomal_eL30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039109">
        <property type="entry name" value="Ribosomal_eL30-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="Ribosomal_eL30-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022991">
        <property type="entry name" value="Ribosomal_eL30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_eL8/eL30/eS12/Gad45"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002172">
        <property type="entry name" value="PRK01018.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11449">
        <property type="entry name" value="RIBOSOMAL PROTEIN L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="L30e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00993">
        <property type="entry name" value="RIBOSOMAL_L30E_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal protein eL8/eL30/eS12/Gadd45" evidence="5">
        <location>
            <begin position="86"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0574772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="20054" checksum="1AE4547C93D70458" modified="2022-10-12" version="1" fragment="single">RTIFTSVHIRPHPGRISHILRSEELGLARRVCPKPSPGPPSLSFCAAPAPGRSFALSPPHLRPPRPHHRSSGTMVAAKKTKKAQESINNRLALVMKSGKYTLGYTTTLKSLRGGKGKLVIIANNCPPLRKSEIEYYAMLSKTGVHHYSGNNVDLGTACGKYFRVCTLSITDPGDSDIIRSMPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVH1</accession>
    <name>A0A8T0HVH1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG283600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5610" checksum="93695B093452E70D" modified="2022-10-12" version="1">MERSRGFRGDHGPEANTWMLQTCDAHQTPEEDIVPVVDHVAETSSQRGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZM8</accession>
    <name>A0A8T0HZM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transposase Tc1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G073100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:DNA transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002492">
        <property type="entry name" value="Transposase_Tc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01498">
        <property type="entry name" value="HTH_Tnp_Tc3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transposase Tc1-like" evidence="1">
        <location>
            <begin position="69"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="30324" checksum="CAEC2A9A5C68560F" modified="2022-10-12" version="1">MRTRTLSNHERGVIIELRNAGIKSGRIAKLLRMLCSTVSTVLIKWKKFGLNTTQKPKPRPPKLSNCTVRDLARLVRRDCRLNLVSIAESFGVHRNTIRKHIRQLGFGGRVAVRKPFLSVIHRKKRLTFGRKDSQRIRVWRKSHEKYVDQCLAPTFKLGRTSVMVWGALNFTGFDKSPLVFLPKGEQTTISFVEHVYDSVLCGFYFMQDASHELLLLEDNLWKTMKNKLRYYKRSSKKEEMRALIQVIWNGISLEQLQRLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0B1</accession>
    <name>A0A8T0I0B1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G073300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0B1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF231">
        <property type="entry name" value="BAHD FAMILY ACYLTRANSFERASE, CLADE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="454" mass="50226" checksum="27893F52E39FA595" modified="2022-10-12" version="1">MGSEAVVAPLTELNVKIDEPEYVKPVEPCENTSPFFLTNADQMLAFTVETMYFYAANPEKPSDTVADTLKMALSKILVHYDFLAGRVRLNEQLKRMEIDRNYAGAQFATASCDLTLAELGDVSVPNALFRKFVPQAHNATTISDIPLMMVQVTTFKCGGHAIGFGMSHLVWDGHGVVDFLFNLTSLAQGGPLVSEPKPNRDMFKARDPPTPVFDHPEYLKLDDLGHVPSLGGPFTTPEAAESEFEGIAPSPKHITQVFPFSAKDLATLKMRAMAEGVLKKVSTFEALAGHVWQARTKAIDALPNDIAQLLYAVDVRDRLDPPLPKGFVGNALYSACARATCEEVRNGPLSFCVQEIQKANQRITNDYIRSGIDWWEVYRGVPAVTSGIFITSWQKMPFYSMDFGWGKPVFAGPAVHPMVEFVIFLPSRHQNGSLDVVLGLQPDVMTRFQEHVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2G8</accession>
    <name>A0A8T0I2G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G169400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2G8"/>
    <dbReference type="OrthoDB" id="6019202at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.60">
        <property type="entry name" value="Arfaptin homology (AH) domain/BAR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027267">
        <property type="entry name" value="AH/BAR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050384">
        <property type="entry name" value="Endophilin_SH3RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167:SF81">
        <property type="entry name" value="ENDOPHILIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14167">
        <property type="entry name" value="SH3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14604">
        <property type="entry name" value="SH3_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00326">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103657">
        <property type="entry name" value="BAR/IMD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SH3-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="7">
        <location>
            <begin position="296"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="146"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="368" mass="40210" checksum="720AE3B9FD14D26E" modified="2022-10-12" version="1">MDAFRKSANKLREQVVKQQHAVLKQFSGHGSGNDVIIDEAELQRHQQLEKLYISTRTAKHFQREVVRGVEGLVSTGSKQSEVANKLADECKKYGTEGPGVGGALSTASLQYGTAKIQMEKERDTMQRVLTTQVAEPLKAMVMGAPLEDARQLTQRYDRLRQEAEAQASEVNKRRTREAGGVDNVVKLQAAEQKMGELSSAMAVLGKEAASAMTAVEIQQQRLTLQRMIALVHAEQAYHQRVAEILDQLQDQLVSQLQKSEANVPSSGAAAGDMFIAQNEDANLGSDSAKPKRNQASNYFLAEVTHPFEAESHGELSLAVGDFVVVRQVAPSGWSEGECKGQAGWFPSSYVEARQRMPGTKVAEAVTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2U9</accession>
    <name>A0A8T0I2U9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G156700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2U9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008093">
        <property type="term" value="F:cytoskeletal anchor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051764">
        <property type="term" value="P:actin crosslink formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00014">
        <property type="entry name" value="CH_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46756:SF18">
        <property type="entry name" value="GAS2-LIKE PROTEIN PICKLED EGGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46756">
        <property type="entry name" value="TRANSGELIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="3">
        <location>
            <begin position="18"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="509"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="403"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0577446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="60337" checksum="ED1F3FE8A6046C99" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3D3</accession>
    <name>A0A8T0I3D3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cysteine-rich transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G162900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CYSTM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3D3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028144">
        <property type="entry name" value="CYSTM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044850">
        <property type="entry name" value="WIH1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31568:SF21">
        <property type="entry name" value="CYSTM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31568">
        <property type="entry name" value="RCG49325, ISOFORM CRA_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12734">
        <property type="entry name" value="CYSTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Cysteine-rich transmembrane" evidence="6">
        <location>
            <begin position="41"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9182" checksum="CF1F5A3D58ED9E6D" modified="2022-10-12" version="1">MAGDKAYPYPQQGYPPQGYPPQGYFQQGYYQQGPPVMGPPQGYYQERPRRNGGGGFLRGCLAALCCCCLVDECCCDPEIFLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3U1</accession>
    <name>A0A8T0I3U1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box/LRR-repeat protein 15-like leucin rich repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G173300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3U1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="2">
        <location>
            <begin position="62"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="624" mass="67995" checksum="1338F8E59548D00A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4H2</accession>
    <name>A0A8T0I4H2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G185400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4H2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035721541" evidence="2">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6218" checksum="C8432A58AC514915" modified="2022-10-12" version="1">MELFLQILLLDYLLNETASQRKTVVRFCISNSAQDPAESTCSSSSTAQKPRYNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4U7</accession>
    <name>A0A8T0I4U7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Endoglucanase</fullName>
            <ecNumber evidence="9">3.2.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G193000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Endohydrolysis of (1-&gt;4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the glycosyl hydrolase 9 (cellulase E) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.4" evidence="9"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008810">
        <property type="term" value="F:cellulase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001701">
        <property type="entry name" value="Glyco_hydro_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018221">
        <property type="entry name" value="Glyco_hydro_9_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22298">
        <property type="entry name" value="ENDO-1,4-BETA-GLUCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00759">
        <property type="entry name" value="Glyco_hydro_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00592">
        <property type="entry name" value="GH9_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 9" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 8 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 9" evidence="12">
        <location>
            <begin position="124"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0577939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="634" mass="70363" checksum="B6B9E5A160244ADC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6A5</accession>
    <name>A0A8T0I6A5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G036400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6A5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001209">
        <property type="entry name" value="ABC transporter, ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="PstB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF1">
        <property type="entry name" value="ABC TRANSPORTER I FAMILY MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="59"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="39"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0578606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="32590" checksum="7FF3B3256A00585E" modified="2022-10-12" version="1">MALMEESVDGGLQLSESFSRRGDDEAREHLLAIPDDSNGHSNHGSRSTSRNDSQRRKSSSHVSIRNLVEPKNQLLKGISVEIKTGQIYCIIGPSGSGKSTFLRSINRLWEPPADSIFLDGEDIVNMNVLTVRRRIGMLFQSPMLFDGTVADNVRYGPSLQGKTLTDKEVIGYLEQADLDASFAQKSIIGLSVGQAQRVALARTLANKPEVLLLDEPTSALDPISTHHIEQSVMELKRSKGLTVIMVSHSFEQVKRIADYVCLIVAGELLEVFKPTELDTVTHPQAQEYLEAAQRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I828</accession>
    <name>A0A8T0I828_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G126900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the drug/metabolite transporter (DMT) superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I828"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030184">
        <property type="entry name" value="WAT1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31218">
        <property type="entry name" value="WAT1-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="60"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="7">
        <location>
            <begin position="250"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="426" mass="46803" checksum="63D879CB10B2C59F" modified="2022-10-12" version="1">MVTRSELDVDKLLLPDGVIAIPPPCSQRLPTTSGTHVELQAENHQHWTKKAIVPFVVLTLVQFLTATFQTLAKVALTSGINPLFFTFYRNVVAFFFLAPFAYFLERDIRPKLTLHTIGSFTLLAFFAILANQQFFLAGLALTSTLFTGVSQNIIPAITFLLATFFGNCIANCRMEKVSFRRTSDLAKILGTVVCITGAVTMTLYKGIALYQQPTGDQDKYILHGSENLHLSFKHLGLPQALQFEIGSWALGVLCLFLNCTSWGLYLIHQGPALKKYPALLSMVTFMELFGCIQVAIVGVAYEGTQFIDFRSITLDQFMIVLYGGILVSAVNLVLQAWCVGQVGPFLVSLFSPVQTLLVALMAVLILGDTLYMGILIGSILIIGGFYIVMCGKQMERRRSALALKCSTNPAGLGDTKQSDLEEPLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I874</accession>
    <name>A0A8T0I874_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G087600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I874"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8114" checksum="69777FD17369269F" modified="2022-10-12" version="1">MAEPGATLSTREAFQSLRSPGCLRAFFCESRIGTKFRTFFSTGVLEVVDRVGFPLDLGYRHLLYDCASVQCMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAJ3</accession>
    <name>A0A8T0IAJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G137000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11746">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="6">
        <location>
            <begin position="23"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="144"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005739-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="40681" checksum="EBE765BB966B0942" modified="2022-10-12" version="1">MGSVGETEKVPTTIDRVRLDAFQLVTMSALPGALAALARLNIFEALAKAGDDAQLTAAELAERALPGKSINMSYLSRLLRMVSGKNILREVVTTTGDKNGAPVAVERRYALEPIARFLVDDPERGSFVHLLLTYQSPGAFLQTWEHLHESVLDDAIQPFARAHGMNAWEFGKHNPQFDKVFNKAMAGNSKIYMRAILDAYHGFEDVKVVVDVGGGFAAALSLITARYPHIKGINFDQPHVIDVCPELPGVEHVSGNMFESVPSGGDAIFMKYILHDWDDESCLKILKNCYQALPAHGKVIAVDNMLPEIIDFEGGDPMALQVDIHMLAFNDSGARERTERELVKLGLAAGFNKVKVVCKVDLLAVTEFHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAJ7</accession>
    <name>A0A8T0IAJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G197200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="10291" checksum="07771A598332B86A" modified="2022-10-12" version="1">MERFMSANISMSFTWQCARSFPRMQSYRQMLGPCTELRASWIFCYLHCAGVLNYSGMDLNRRSTWRDSVPVVGTVNFFRMKWLWNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHH1</accession>
    <name>A0A8T0IHH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exonuclease V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G054000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHH1"/>
    <dbReference type="OrthoDB" id="354769at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045145">
        <property type="term" value="F:single-stranded DNA 5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="536"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="66795" checksum="E0B289156A5FDCC1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II28</accession>
    <name>A0A8T0II28_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G062200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="4155" checksum="2A3A3C14E66AD492" modified="2022-10-12" version="1">MNIHGIVRLKMPLESLFLLLKLSFTIHDVFVEPCTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II77</accession>
    <name>A0A8T0II77_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G138700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF4">
        <property type="entry name" value="OS02G0174300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="363"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="513" mass="57532" checksum="1776E3EF403A68A6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKT7</accession>
    <name>A0A8T0IKT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G140200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37203">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37203:SF3">
        <property type="entry name" value="SLR0975 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="370" mass="40874" checksum="DDEFF6032BFBAF3C" modified="2022-10-12" version="1">MELCYSTALPARLRHHHHLKAAPLVCSWSAIRSLKGDFLAGTQLRLGSNSHLVQTGTSGRRKNALRTVTAAFDPELHSVLELASDAELTELSNILYGQSPLSPLLKSVAPGDGSNRGTIAEAMHEQQYGGRDALMERLESRFMFLAADAKATLSGRRPTYRDVLLRVRSKLNVPCSIKLSTEDMEAEIFLHLLQDYSSQPKKRPQPKRRVPYLEAIERAKGSRFRDNISSAIRLGSEELLTTILKGSSAVTMSTLQRFITKKLSGKVLVETARYQLAKEALVKGGQAVAAKLESQVAMLAARQTLAGAATRYMTLRSTMMVLGPLLWGTFLADVVIRSIGTDYARVVRAIYAFAQIRLSRTYGWTRAETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMX1</accession>
    <name>A0A8T0IMX1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G170700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMX1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035899603" evidence="2">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="189" mass="20384" checksum="CBBBAB8552B6C27A" modified="2022-10-12" version="1">MVGVGVLAGSSVMLLTIAWAGSLIAGRCDLTGPSVTATDLTLTRPFDPVGTGVTTDEQTRVGAWIMMLSTLPFLFAQLPLLPGHLEDGPTAALGGCIVASVGLLAYSAYQVASPWLQQKKVEEARLQFCCSRALQRVASFPMRSTSRTNRLFQPFNQFYFSLSPSLAVLSSLCARFLKNIKLLGFNYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP76</accession>
    <name>A0A8T0IP76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G223300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="14294" checksum="86D9515CCCFF0B80" modified="2022-10-12" version="1">MERMQNRKRVCGLEFVGYNLNRVWGHLLGFKLPGASFYHTFARAVRFTDGYGERDGGRYAFGAGMGTKGCAIGVLMMRCKRERARCGDQRLLTADVHCNEEPLALRPWLGLWKSTPPQLEERRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPA6</accession>
    <name>A0A8T0IPA6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G236900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPA6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="13810" checksum="055C83082E21176F" modified="2022-10-12" version="1">MNSSLKRAKKIPASYAHHIQQQKIVKNGKSNVLTKLQQPIPMQNLANRLTGSASVAFTHIHTPATPTTPASSTISHGVQHTTPIPVPQSLRTKPSRTFSATIATQIQPPQKRKHPQQTNLHQNLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITP2</accession>
    <name>A0A8T0ITP2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G034700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11839" checksum="49CB62E1EDA1283A" modified="2022-10-12" version="1">MRCKVFVTNSNLLEAEFISRIQTRIHMRCASPFRESQLSTCTKNLIAIYGCYLSPAQIEHKRIVDVLVSKTFDLLVKLTSVPESVIAILTSSKEILELHGWPLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVB9</accession>
    <name>A0A8T0IVB9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ferritin</fullName>
            <ecNumber evidence="14">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_2G141400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="14"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01056">
        <property type="entry name" value="Euk_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.10:FF:000006">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014034">
        <property type="entry name" value="Ferritin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431:SF75">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00540">
        <property type="entry name" value="FERRITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00204">
        <property type="entry name" value="FERRITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="15">
        <location>
            <begin position="93"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601519-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0587117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="29218" checksum="42D5AC6B3E32A56F" modified="2022-10-12" version="1">MVMLQVAAAGSVTTPAAASLAASRSGVAGGFSACRCVVARTGLQSRGVVSVRASSNDVSTKAVTGVVFEPFSEVQDQLVKVTTSPGLESLARQRFAPSCEAAINDQINVEYNVSYVYHALYAYFDRDNVALPGLAEYFRAASDEEREHAEKLMKYQNQRGGRVKLQSIVMPVMEFDHTEKGDALYAMELALALEKLTNEKLLQLHQAAADANDPQMTDFVEGEFLTEQVEAIKKVSEYVAQLRRVGKGLGVYHFDLQLQEEQEAAQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWJ9</accession>
    <name>A0A8T0IWJ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G172000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035874831" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="5877" checksum="DA8803B6A9145D74" modified="2022-10-12" version="1">MLPHPLFCSISINILMATSSLQHPWAACNSVITHLTSLTSRVQNFKPVLSTAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX49</accession>
    <name>A0A8T0IX49_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G232600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone deacetylase HD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.340:FF:000004">
        <property type="entry name" value="Histone deacetylase HDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.340">
        <property type="entry name" value="Nucleoplasmin core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041232">
        <property type="entry name" value="NPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17800">
        <property type="entry name" value="NPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="191"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="37201" checksum="FB6419A0881184E7" modified="2022-10-12" version="1">MEFWGVEVPSGKPTSCHPGDGMYLHVSQAALGESKDKSGKGNARVVLKVQVDDSEVVLGTLSEGKCDQMPLDLVFDREFTVSHNSSSSSVYICGYRTEGPEYDDSEEEEDEEEEEDMPVAVPIESNGASAGKQLKAKAEDAAKKAVEKATTNAAQKKGVKKQVVESSSDEEDESDDEDEGMGHPFVSDLASESDDEFDAGDDSDEDMDEDDDDEDDDEDDEDESDESEEEELKIEAPKPGKKRAAEELAKSAEKKSKTDASSKPGQSPGKKGAKAGPATPVGKVAAPAEVKTPTDKGSKPAKAPKGTPTAPPTTPVSEKKIGQHKCTGCDRTFVTESAMTQHIAAKHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1G8</accession>
    <name>A0A8T0J1G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G281800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000480">
        <property type="term" value="P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000447">
        <property type="term" value="P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000472">
        <property type="term" value="P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040000">
        <property type="entry name" value="NOP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13102:SF0">
        <property type="entry name" value="NUCLEOLAR PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22493">
        <property type="entry name" value="PUF_NOP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="800"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="726"/>
            <end position="760"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="826" mass="90150" checksum="0339EB1086739C78" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J379</accession>
    <name>A0A8T0J379_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G031400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J379"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5882" checksum="081466EB03BEC774" modified="2022-10-12" version="1">MASLDTLPFARHFPQSATASRTSRTCEREFMRTEVYASFEHGGSWSERREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3Q2</accession>
    <name>A0A8T0J3Q2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G081200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoethanolamine + S-adenosyl-L-methionine = N-methylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58190"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:20366"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from phosphoethanolamine: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3Q2"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006656">
        <property type="term" value="P:phosphatidylcholine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025771">
        <property type="entry name" value="Phosphoethanolamine_N-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51582">
        <property type="entry name" value="SAM_PEAMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="9">
        <location>
            <begin position="57"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltransferase" evidence="10">
        <location>
            <begin position="281"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0590207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="492" mass="55985" checksum="ACA6A03FAEFB4D91" modified="2022-10-12" version="1">MAVYTERTIQSNYWKEHSVEPSVEAMMLDSQASKLDLEERPEILGLLPPFKGKNVVELGAGIGRFTGELAKTAGHVVAMDFMENLIKKNEDTHGHCGNIDFKCADVTSPDLDIPDSSTDLVFSNWLLMYLSDEEVATLTERIMKWLRPGGYIFFRESCFHQSGDHKRKNNPTHYRQPSDYTKIFEQTHVEEADGSFYEFELVGCKCVGTYVRNKRNQNQVCWLWKKVPSDGPAAKSFQKFLDTQQYTATGILRYERIFGEGFVSTGGMETTKEFVNMLDLKAGQRVLDVGCGIGGGDFYMAEEFDAEVVGIDLSVNMISFALERSIGRKCAIEFEVGDCTKINYPDASFDVIYSRDTILHIQDKPALFSRFYKWLKPGGRVLITDYCRAAKTPSEQFAAYIQQRGYDLHSVQTYGQMLQGAGFIDVVAEDRTDQFVEVLKRELEVTEKARDKFISDFSEDDYNYIVSGWESKLKRCSADEQKWGLFVAHKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3W6</accession>
    <name>A0A8T0J3W6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G056700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009524">
        <property type="term" value="C:phragmoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000052">
        <property type="entry name" value="Kinesin-like protein KIN-12F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044986">
        <property type="entry name" value="KIF15/KIN-12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739:SF16">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIN-12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="158"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="748"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="961"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1247"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="503"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1119"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="979"/>
            <end position="1000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1255"/>
            <end position="1266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="235"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1363" mass="150601" checksum="D4188606ABBE0C04" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J716</accession>
    <name>A0A8T0J716_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G115100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J716"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035904907" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8906" checksum="87576987380C00BC" modified="2022-10-12" version="1">MHIVVLLLVLLSPVTISSTVPKRYHELLLLLCQSPQPVDIISGPGSCMLLVSLLEYYNQVQTILVCHICSLGRRPLHSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7G2</accession>
    <name>A0A8T0J7G2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3,4-dihydroxy-2-butanone kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G186100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dihydroxyacetone kinase (DAK) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7G2"/>
    <dbReference type="OrthoDB" id="1724672at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1180.20:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10440:FF:000001">
        <property type="entry name" value="Dihydroxyacetone kinase, DhaK subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.340:FF:000002">
        <property type="entry name" value="Dihydroxyacetone kinase, L subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10440">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.20">
        <property type="entry name" value="Dihydroxyacetone kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012734">
        <property type="entry name" value="DhaK_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050861">
        <property type="entry name" value="Dihydroxyacetone_Kinase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02361">
        <property type="entry name" value="dak_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011049">
        <property type="entry name" value="PRK14479.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629">
        <property type="entry name" value="TRIOKINASE/FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28629:SF4">
        <property type="entry name" value="TRIOKINASE_FMN CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82549">
        <property type="entry name" value="DAK1/DegV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="DhaL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="9">
        <location>
            <begin position="10"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="DhaL" evidence="8">
        <location>
            <begin position="381"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-hemiaminal-histidine intermediate" evidence="6">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="61"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR612734-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0591587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="590" mass="60780" checksum="0C23385EA2FD06CC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAD0</accession>
    <name>A0A8T0JAD0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G274800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677">
        <property type="entry name" value="AP2 DOMAIN CLASS TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31677:SF75">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="313"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="403"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0592707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="540" mass="58965" checksum="2F0594A63F61ED0D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDA1</accession>
    <name>A0A8T0JDA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G272400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035809033" evidence="2">
        <location>
            <begin position="24"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="16198" checksum="E321734D700A25C8" modified="2022-10-12" version="1">MALTGKLVLLMGLFVASSVMAAAQPEDPNNQGAVTVHNPALLPLDILVDDKAVRVTTQSATMELAHQEQPLQISVAGGDYEPVAITVHDGDNLMVMPDPANTGILQAYIMQKAGEEPRAQVQPAEEPNPDVRPADGPKSDVRPVAVPRPALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDL2</accession>
    <name>A0A8T0JDL2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G332100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDL2"/>
    <dbReference type="OrthoDB" id="1910373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025397">
        <property type="entry name" value="SDH5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36139">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE SUBUNIT 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36139:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE SUBUNIT 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14290">
        <property type="entry name" value="SDH5_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035891089" evidence="1">
        <location>
            <begin position="21"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="240" mass="25536" checksum="D7E7B40BF633715D" modified="2022-10-12" version="1">MAIAIAIAMALARRATRLVAAPLVLRCSSAAPALHHISHLRPSSPADRSMARGILSHISVTSKVRCMASASFVSNLPPIQDVKIAKALSGLLGHGWLKIEPQVRSAVESAISGGSDDSAGKETLIDAWKAAQAVESFGGLLVDMLLEINDLCGDTGENVGTIPNSTYEAVEAAHKKYMLYLSAFGGDEVYLRKKVETELGGMLLQIKQRLTGMDPKWAEISVLGTSGLAGSYIEKRRLPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDM3</accession>
    <name>A0A8T0JDM3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G332800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDM3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="17775" checksum="3C0CB8FAC2340DB4" modified="2022-10-12" version="1">MRSQTTTAPRPKLDRPGPPVLPPQICSKTRGVAANTSNLARPGVSSSSSSSSATTALSPANSTPPATRQPGRSLWESPQPSQAKPSPRAAFARGSLLAVPIVAPAASRRSTEHSHGPRKRRPRCRVGAQRQLPSGAAPRLPSRQAPPESRDPSSLACFREETRLRPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G755</accession>
    <name>A0A8T0G755_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G033000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G755"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002259">
        <property type="entry name" value="Eqnu_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10332:SF10">
        <property type="entry name" value="EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01733">
        <property type="entry name" value="Nucleoside_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016379">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01130">
        <property type="entry name" value="DERENTRNSPRT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0553708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="438" mass="48162" checksum="F7BC5A55E7321866" modified="2022-10-12" version="1">MGWVVGRAEAEKEENQPLTAAAVPKDDYNLAYLIFFLLGAGFLLPWNSFISAVDYFDVLYPHSHIDRVFSLAYMIPCFLFLLGLTFYGQHYPSRVRVNLGLVIFLTVFILVPVMDEVWITGNKGTTTTHVLTVGAASVLGLCDALVQGSLIGSAGELPERYMQALIAGTAASGVLASLLRVITKASMSQTIRGLRLSADVYFIVTAVILLLCLVSYNLVYKLPIMLHYNSVKIGAMESTLSNAPHDASELGLKTDATEISLITTGDSELTNFAKPVSYWHVWSQIQWLAGALFLIYVVTMSIFPGYITEDVHSELLGDWYPVLLIAAYNVADLVGKILTSVYIVENQTLMVRACFGRLIFFPLFYTVLHGPAFFRTEAPVFLLTFLLGLTNGYFTSILMIVAPKNVSILESETAGIIMTLFLVTGLTAGSLLGWVWII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G950</accession>
    <name>A0A8T0G950_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G180800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G950"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="39"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="971" mass="110344" checksum="F03E47C36B38152F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAH8</accession>
    <name>A0A8T0GAH8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G165100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAH8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035894077" evidence="2">
        <location>
            <begin position="25"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="668" mass="75813" checksum="B82826953D8C9F07" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBW8</accession>
    <name>A0A8T0GBW8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G005900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBW8"/>
    <dbReference type="OrthoDB" id="1658724at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="7">
        <location>
            <begin position="104"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0555824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="291" mass="33260" checksum="C5721255B59E257E" modified="2022-10-12" version="1">MEVGNFLLCAVMGVLGGIGVGVMHATFEHLWYHTLDWLHRGGHIQRLAPQIDVTQNQYHKESFWATAIGPIPVSAAAFYLRHGFISRMQVSSDIVGSLLFTWTVMVLHDAYFFAVHTLMHYFKSVYKQVHQWHHATHGDLTVFNTAYGDILDVTFTFAPFYAAVVAYVYCQPTWNPVDVMFLMWAVNGVDMMGHCGYKLPPWVYVPGSMGVLLTPLAQRPKHHYIHHLDPRYNRSLYFTWWDRLAGSFREDHPKVVNDISTASNCSSEVQTSFVCSNSEQFSKAANDKQFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCL3</accession>
    <name>A0A8T0GCL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glyoxylate/succinic semialdehyde reductase 2, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G025300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glyoxylate to glycolate as well as succinic semialdehyde (SSA) to gamma-hydroxybutyrate in vitro. May function in redox homeostasis and play a role in oxidative stress tolerance by detoxifying glyoxylate and SSA generated in glycolate metabolism and GABA metabolism, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>4-hydroxybutanoate + NADP(+) = succinate semialdehyde + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26381"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16724"/>
            <dbReference type="ChEBI" id="CHEBI:57706"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.n11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>glycolate + NADP(+) = glyoxylate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29805"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.79"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the HIBADH-related family. NP60 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030267">
        <property type="term" value="F:glyoxylate reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000016">
        <property type="entry name" value="Glyoxylate/succinic semialdehyde reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000058">
        <property type="entry name" value="Putative oxidoreductase GLYR1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002204">
        <property type="entry name" value="3-OH-isobutyrate_DH-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029154">
        <property type="entry name" value="HIBADH-like_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051265">
        <property type="entry name" value="HIBADH-related_NP60_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580:SF2">
        <property type="entry name" value="CYTOKINE-LIKE NUCLEAR FACTOR N-PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43580">
        <property type="entry name" value="OXIDOREDUCTASE GLYR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14833">
        <property type="entry name" value="NAD_binding_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00895">
        <property type="entry name" value="3_HYDROXYISOBUT_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase NADP-binding" evidence="9">
        <location>
            <begin position="84"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="3-hydroxyisobutyrate dehydrogenase-like NAD-binding" evidence="10">
        <location>
            <begin position="246"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00052582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00056683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0556094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="393" mass="41074" checksum="40FE70C7DE620F5A" modified="2022-10-12" version="1">MEAVAMAKGVLTMAHKPLLLNCLFSRSSSITSKSGVIFPGLQHGYRRSFVSTSDATSARSGTAWSKRSFVVRASSAAGEEKQPSIGFLGLGIMGTAMARNLVKAGYEVTVWNRSISKCDALVSEGAKRGETPEQTTAACDITFAMLADPAGAMEVACGPQGAVKGLSAGKGYVDVSTVDDETAKAISDAVRKTGAEFLEAPVSGSKKPAVDGTLIFLTAGDKSLFERASPMLDVMGKSKFYLGDVGNGAAMKLVVNMVMGSMMASFSEGLLLGAKAGLDPKTVIEVIGQGAISAPMFAMKGPSMVEGQYPTAFPLKHQQKDLRLALELANKVGQPSPIAAAVNDLYARATKNGLGDEDFSAIIEALKACKRTQLSNNEKTGITNSSTLRFSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCZ6</accession>
    <name>A0A8T0GCZ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta-amylase</fullName>
            <ecNumber evidence="3 10">3.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G036300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016161">
        <property type="term" value="F:beta-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000066">
        <property type="entry name" value="Beta-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001554">
        <property type="entry name" value="Glyco_hydro_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018238">
        <property type="entry name" value="Glyco_hydro_14_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001371">
        <property type="entry name" value="Glyco_hydro_14B_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352:SF47">
        <property type="entry name" value="BETA-AMYLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01373">
        <property type="entry name" value="Glyco_hydro_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00750">
        <property type="entry name" value="BETAAMYLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00842">
        <property type="entry name" value="GLHYDLASE14B"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00506">
        <property type="entry name" value="BETA_AMYLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="276"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="472"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="384"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="473"/>
            <end position="474"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="508"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0556224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="60538" checksum="66C2FAD42B43C4DF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEK5</accession>
    <name>A0A8T0GEK5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G131500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEK5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="12875" checksum="1BBC6EF9B73355D0" modified="2022-10-12" version="1">MTQLLRVGQGLKGCEQVEFGGFSRERAVERGSGRVRIGGVVAPKAFFGIGGAGGGKAQAPAGKGCGKCKGKGGVECQGCKGTGKNKKNGNMFERWKCYDCQGFGLVKCPSCGARGLTPEQRGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFU4</accession>
    <name>A0A8T0GFU4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_11G163800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion intermembrane space</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="13">Binds 1 heme group per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010336">
        <property type="term" value="P:gibberellic acid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000001">
        <property type="entry name" value="Cytochrome c iso-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002327">
        <property type="entry name" value="Cyt_c_1A/1B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11961">
        <property type="entry name" value="CYTOCHROME C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00604">
        <property type="entry name" value="CYTCHRMECIAB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5 11 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11 13" id="KW-0408">Iron</keyword>
    <keyword evidence="7 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="14">
        <location>
            <begin position="10"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0557880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="11775" checksum="8F747ED537DA3104" modified="2022-10-12" version="1">MATFGEAPKGNGKAGEKIFKTKCAQCHGIAKSEGHKQGPNLSGLFGRTSGTAAGYSFSAANKAKAVGWNETTLYDYLLNPKKYIPGTKMVFAGLKKPQDRADLIAYLKSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJF7</accession>
    <name>A0A8T0GJF7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G022900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJF7"/>
    <dbReference type="OrthoDB" id="10547472at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021584">
        <property type="entry name" value="TSP9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037244">
        <property type="entry name" value="TSP9_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11493">
        <property type="entry name" value="TSP9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144256">
        <property type="entry name" value="TSP9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="9548" checksum="C8F56F8F1722A249" modified="2022-10-12" version="1">MAMAMGVASMAAVTVPRNSSLVCRASATNTGEKQGFLDWFRDALDKDALRETDELLGKVDGGKGSNGKAAPAAKKAAAAPAIKKAGFNFFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJS3</accession>
    <name>A0A8T0GJS3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_11G123500</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000168">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase IX.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000108">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase S.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="344"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0557362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="652" mass="71914" checksum="6FB38C14E4B9CC60" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKR2</accession>
    <name>A0A8T0GKR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G082800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035717393" evidence="2">
        <location>
            <begin position="21"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="320" mass="34661" checksum="13FB4494BD37C376" modified="2022-10-12" version="1">MGLLHRCGCLLLLLSHWGSCCLLLHNWGSRCLHLLHLGCSVSDLLLHYASFRCLSHHRGSLLNGGSNLLLLLSLGHCELPGGNLQRSRGLLHGCSHFLSLLLHNRGHYWGSLLLNGRHRCLLNCWGSLKGLLHRCGCLLLLLSHWVGLEAVCGQKGAESVAEESPRATVPKAAATSPPSKGPSPSSASKISTISSHKPESVPSPATRASSPSWLSNTGRNQERERTKPVAMTSANVSDQHQAPTIGGKNSIPADFLSNAVPVWGVDELLNLPELADGYHMGDIGSSKVLLKCHCDTYITSVVYICELLILLHIIIIYDIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMF7</accession>
    <name>A0A8T0GMF7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G008500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMF7"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="929"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
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        </location>
    </feature>
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        <location>
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            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="389"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="821"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="929"/>
            <end position="947"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1047" mass="114335" checksum="28BD63DE1D14BBC7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNB5</accession>
    <name>A0A8T0GNB5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G033300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030048">
        <property type="term" value="P:actin filament-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053099">
        <property type="entry name" value="WAS/WASL-interacting_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48226">
        <property type="entry name" value="OS06G0326200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48226:SF1">
        <property type="entry name" value="WAS_WASL-INTERACTING PROTEIN FAMILY MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="194"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
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            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1097" mass="120627" checksum="4EDB8AB6A9C32D0C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNK3</accession>
    <name>A0A8T0GNK3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G041900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10645" checksum="3D7F3B083504FA8F" modified="2022-10-12" version="1">MHLSINQLTFMLSLDPSRRHHTISAPERGKSRARLQCEGGNRAMAHGALGFKRGGWTGGRMQSFVNWTPGGGGDAVEEVGRAEGAWTGGLDGGAGDRGTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR71</accession>
    <name>A0A8T0GR71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G013400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR71"/>
    <dbReference type="OrthoDB" id="1938000at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005202">
        <property type="entry name" value="TF_GRAS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31636">
        <property type="entry name" value="OSJNBA0084A10.13 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03514">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50985">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="229"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="786" mass="86831" checksum="93DAA8FC2B67BACB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS55</accession>
    <name>A0A8T0GS55_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G029700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS55"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000792">
        <property type="entry name" value="ABC transporter F family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001124">
        <property type="entry name" value="ABC transporter F family member 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF14">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="168"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="499"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="433"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0561004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="726" mass="79490" checksum="AE2BE82468A2B624" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV53</accession>
    <name>A0A8T0GV53_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G147100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV53"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="16990" checksum="31EEB795E6F4C3F3" modified="2022-10-12" version="1">MTGATRQKVHPTVAFFYTSFLGGGEAIVPRSDPLLDFLHPCSRSLSTAFGGELARTERKSYFCATSKLFVGIVDRFTSGAWFCSRRGEAIGAAVTIDDEWRIPCEQDLPLLRPPFVLILMLIILGEDRICPEGLTVPLNSTSCTWNFGRITIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVN1</accession>
    <name>A0A8T0GVN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G160800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035867428" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="46" mass="5097" checksum="2F57A13146A3C810" modified="2022-10-12" version="1">MCVCFLLIHTITSPVCVHCEITTTNNNNNNKQSTCGSCGLLYNLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVY4</accession>
    <name>A0A8T0GVY4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G068800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVY4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051028">
        <property type="entry name" value="Mito_Solute_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678:SF9">
        <property type="entry name" value="CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45678">
        <property type="entry name" value="MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="412"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="510"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="592"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0563911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="682" mass="73313" checksum="6B1DE8739BF2D3BB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1B4</accession>
    <name>A0A8T0H1B4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G123000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1B4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7317" checksum="CB1375A3B2935CA8" modified="2022-10-12" version="1">MLPFFIYSKYTNCCRRVWETGKLAPAAKYIPMVHGLSGFGSARNQRLLEHADGLVTRLDARKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2G1</accession>
    <name>A0A8T0H2G1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G036000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="8052" checksum="4C55C71959D262EC" modified="2022-10-12" version="1">MRTLSSKLAKVSLECSYALFTQLCTHCFVLNGCREQEWMLGFCRKSSFDPGSTTFLESIFHLNRPLPLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3A9</accession>
    <name>A0A8T0H3A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G043000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3A9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106300">
        <property type="term" value="P:protein-DNA covalent cross-linking repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="entry name" value="SOS response associated peptidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604:SF0">
        <property type="entry name" value="ABASIC SITE PROCESSING PROTEIN HMCES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="DC12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="BB1717-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="251"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="313"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="330"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="367"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="391"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="416"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="443"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0563582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="455" mass="50709" checksum="1520BE5ABD0ED309" modified="2022-10-12" version="1">MCGRARCTVRVDSVGAACGFRAPLRAVNADRYQPSYNVAPGAHMPVVRHDGAGDAREPVVHCMRWGLVPSFTKKSERPDFFRMFNARSESVHEKTSFRRLLAKNRCLATLEGFYEWKKDGKQKQPYYVHMEDGHPLVFAALYDTWESPEGETMYTFTILTTRASKRLEWLHDRMPVILKSQDAIDSWLNSELSEDSIHKLTQPYESPDLTWYPVTPAMGRPAFNGPECVEEIKPKVASESKIAQMFGKQLAHQNTGPADKGMSPSPERRVSPYPNKGMSPNSDKGMSPDFRDGDYLNEEDFKALLAGMEPDQDVTKAVSHPEGPVDRSKTSALSNDSSSLKEQLHEDPRPHQDKDTETPGPSPQLVKSEEENHSPHANKEEESATLGRTHGPTSVKISPVSTPVKPQARKASPAAKDNDSKRQRTTDTSKLTSKTALDAGAKQKQSNLLGFFSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3I8</accession>
    <name>A0A8T0H3I8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G020400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3I8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="227" mass="25684" checksum="586E32D2A125B1C9" modified="2022-10-12" version="1">MHAARALRHALRGSIRSVPIQDRRRAGAVAVLTRESHLARSPREHLRRVVPLQRHLGRLHVRRLLLGVPQTRPRRIHRVVQIGPARVAPARELDVDLVVEVRALVREQAQHDVLVEHSRGRARGTLDLPHERPVLEGPIGVNLRRQPSSAFLAELEMQFPGRVDPDGGGTVGPPVRSWALRRGRCAAHCPCEARPLYLARHHYHQRPVLRRTSISSQADRSLQLHKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3S0</accession>
    <name>A0A8T0H3S0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-related modifier 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G027200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 6">tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of the MOCS3/UBA4 homolog, then thiocarboxylated (-COSH) via the rhodanese domain of the MOCS3/UBA4 homolog.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the URM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3S0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032447">
        <property type="term" value="P:protein urmylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01764">
        <property type="entry name" value="Ubl_Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03048">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015221">
        <property type="entry name" value="Urm1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14986">
        <property type="entry name" value="RURM1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09138">
        <property type="entry name" value="Urm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037379">
        <property type="entry name" value="Ubiquitin-related_modifier_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="MoaD/ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4 5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="modified residue" description="1-thioglycine" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)" evidence="5">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11191" checksum="D1DE45513369F1FD" modified="2022-10-12" version="1">MHLTLEFGGGLELLFGSQKKHEVDVVPPNGMKEVTMESLLAWIKENLLKERPEMFLKENSVRPGVLVLVNDSDWELCGRLETVLEEKDEVIFISTLHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H417</accession>
    <name>A0A8T0H417_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G028100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H417"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035717928" evidence="1">
        <location>
            <begin position="25"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12885" checksum="BFC77506D26BA725" modified="2022-10-12" version="1">MHTLLVSANSFAMLPNLLLCQVSSNSTPIEATAITNHRACFYSDTYTKCFDCPALPTSNSTQATRSQPLPTLKIMSKLHNPNVPEPYYPKPSLLVLAPCFPDAINSSNCNSLTLHSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H512</accession>
    <name>A0A8T0H512_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G189000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H512"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="223" mass="24563" checksum="65E55B0D011E6F5D" modified="2022-10-12" version="1">MSKRGSSLVPIVDALPEEAPPPPPPRDPKVPLTFDEMWFNADDEIQDEEVRNHAKELKAHIMVKATEVRRYLEDGLMVAVILQALQHMIVDRPLDPFRYLAHFIKGEGPNIADEIERAKRLAAAKQAARDKAKRDGDEADRLAREAAEAAAKALRDREAAKLAAAARKAAEDAKIAGMLRLQQSAAKAAAVAADAIEIPIPKAEKRKKAPSLKQLPNKPSWQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5G0</accession>
    <name>A0A8T0H5G0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G102800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5G0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47543">
        <property type="entry name" value="OS08G0169600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47543:SF2">
        <property type="entry name" value="RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="76"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="14924" checksum="1188073E6F493FE3" modified="2022-10-12" version="1">MVKERMSSRGIKFKWRQLYQAKVREQEELQKKGVNRLKDIYREQNTQKESRKCQAIDLKPPESKRIKRTGPGAGSSGSSSKAPAKGRLMQKSRMDFAKSNAVSRQATMARNRSNIRSTNGINQRPGGTSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5I5</accession>
    <name>A0A8T0H5I5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c-552/DMSO reductase-like haem-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G072800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5I5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00241">
        <property type="entry name" value="DOMON_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019020">
        <property type="entry name" value="Cyt-c552/DMSO_Rdtase_haem-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36044:SF1">
        <property type="entry name" value="HEME BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09459">
        <property type="entry name" value="EB_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035746904" description="Cytochrome c-552/DMSO reductase-like haem-binding domain-containing protein" evidence="7">
        <location>
            <begin position="22"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c-552/DMSO reductase-like haem-binding" evidence="8">
        <location>
            <begin position="61"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF09459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="369" mass="39018" checksum="518832774B0B44E0" modified="2022-10-12" version="1">MARPRLALALFLLALCAHVHVLPVWSHGDTGSTGAACLRNVGVKLQASFLPGLVTIDGLAADWSSVSGSSFQLNPALTDDSANAYPGGSMQIKVAHDGHDVFFLVQVPGAYMFDANEQNMAAMALMFPIGDDATYHNMGGCPEPAGVCNSTNCFGHEVDLIHFELNQAIPGRLYGGNLADSINGTGRDSIGKLNDAYAFNPHCRSYDGMTPSGLLTGGGLNNWRGSWTHSTTDTAYGLVATDSPFGALDGAGTYTFEFARPLRTSDVLQQDAQFTIGSTHGMAAAFWFPTGANSGWQPYQHYSASCDWLQLEIISGASSSIGTSRSWSALSTVSLLVSLMSLAVAVAVGWWVRQSTGSRVSFNPISSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9B3</accession>
    <name>A0A8T0H9B3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G093100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9B3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000760">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053070">
        <property type="entry name" value="RING-type_E3_ubiquitin-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47035">
        <property type="entry name" value="OS11G0150450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47035:SF3">
        <property type="entry name" value="OS11G0150450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="515"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="362"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="597"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="650"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="663"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="710"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0566858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="757" mass="83091" checksum="445861A3499AEF2A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBE2</accession>
    <name>A0A8T0HBE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G178300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035727791" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7083" checksum="4803A6917402950C" modified="2022-10-12" version="1">MLACLLACMLACLLACCPCGVVWRGQVLNCGFFLSACVTQEWDDDGSWIMGGGPDSLPSGEQKPNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBI1</accession>
    <name>A0A8T0HBI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G154400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035847250" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11334" checksum="5502B10FF6C93E7C" modified="2022-10-12" version="1" fragment="single">MISRGIFTLLFRIHGWVRACAAVMRLRISLFSNRFTKSFASGETEGQGASSKLRSALNAARKIPDSVRTQKGRLPQSKMYVITLMLNTSASIEYDLCSTSGAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC42</accession>
    <name>A0A8T0HC42_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G168600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035928643" evidence="2">
        <location>
            <begin position="25"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="13999" checksum="077484093505D695" modified="2022-10-12" version="1">MNRWQPTQMYIIVFMYVGCLEGLAENSMLTSSTSTCYARKMEAWPFKFNQHWQFSLYHLGRKLIYSFAGCFTTLIHVHWWFYFLEWMDWTWMLFTMCALCRMVRLSVCTYWFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC58</accession>
    <name>A0A8T0HC58_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G062000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="172" mass="19603" checksum="98366CA61146065A" modified="2022-10-12" version="1">MKLGQTFISILFRHSPGSIGVLGCFQIKTVNGDASTSTNSVQSSKKWLQVLSLQPSQQRNSVTHAQCHPLCTRQATMCRLHGLFKSSTARSRRYLPYFTHEIQLETLAAENILLSSNAKFLNERIKNQRQYEVTSPQCFRYEKSVNNGEPLIFVFRYTAIQQDTCTPIIVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCC4</accession>
    <name>A0A8T0HCC4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">glutamate synthase (NADH)</fullName>
            <ecNumber evidence="23">1.4.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">KC19_6G011500</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="29 30" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="29 30">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="24">
            <text>2 L-glutamate + NAD(+) = L-glutamine + 2-oxoglutarate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="26">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
        <text evidence="26">Binds 1 [3Fe-4S] cluster.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Nitrogen metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.14" evidence="23"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048589">
        <property type="term" value="P:developmental growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00713">
        <property type="entry name" value="GltS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000031">
        <property type="entry name" value="Glutamate synthase 1 [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1060.10:FF:000009">
        <property type="entry name" value="Glutamate synthase 1 [NADH] chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000043">
        <property type="entry name" value="Glutamate synthase 1 [NADH] chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000017">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000113">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000022">
        <property type="entry name" value="Glutamate synthase [NADH], amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.60:FF:000001">
        <property type="entry name" value="Glutamate synthase, large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="entry name" value="Alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="entry name" value="Glutamate synthase, alpha subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012220">
        <property type="entry name" value="Glu_synth_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051394">
        <property type="entry name" value="Glutamate_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008730">
        <property type="entry name" value="PRK11750.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43100:SF1">
        <property type="entry name" value="GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000187">
        <property type="entry name" value="GOGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="Alpha subunit of glutamate synthase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46548">
        <property type="entry name" value="alpha-helical ferredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="22 26" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="12" id="KW-0288">FMN</keyword>
    <keyword evidence="21" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="16" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="18" id="KW-0408">Iron</keyword>
    <keyword evidence="19 26" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-0520">NAD</keyword>
    <keyword evidence="17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="28">
        <location>
            <begin position="140"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="27">
        <location>
            <begin position="1068"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="27">
        <location>
            <begin position="1682"/>
            <end position="1707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="27">
        <location>
            <begin position="2202"/>
            <end position="2221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="27">
        <location>
            <begin position="2202"/>
            <end position="2212"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="25">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1290"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1296"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="26">
        <location>
            <position position="1301"/>
        </location>
        <ligand>
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00024383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00048867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="PIRSR" id="PIRSR000187-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="27">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAG0568317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2221" mass="243345" checksum="4FDA9D6971054B34" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD03</accession>
    <name>A0A8T0HD03_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G181100</name>
        <name evidence="3" type="ORF">KC19_7G181200</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11054" checksum="4531DAD2BC181633" modified="2022-10-12" version="1">MCFVREWCVGFFANAMHPWLSHMMVVASTWTHPTSPKSLRSQMASLVLWLVAMYSASIVDKAIVGCLLQFQEMAPSPTKKTYPVVEQRSFASPAQSASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF56</accession>
    <name>A0A8T0HF56_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G042000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasmic vesicle membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <location evidence="6">Coated pit</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the clathrin heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2113814at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030132">
        <property type="term" value="C:clathrin coat of coated pit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030130">
        <property type="term" value="C:clathrin coat of trans-Golgi network vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071439">
        <property type="term" value="C:clathrin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009506">
        <property type="term" value="C:plasmodesma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032051">
        <property type="term" value="F:clathrin light chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000001">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000005">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000686">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.730:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.110:FF:000002">
        <property type="entry name" value="Clathrin heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.110">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055358">
        <property type="entry name" value="CHCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015348">
        <property type="entry name" value="Clathrin_H-chain_linker_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016025">
        <property type="entry name" value="Clathrin_H-chain_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022365">
        <property type="entry name" value="Clathrin_H-chain_propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016341">
        <property type="entry name" value="Clathrin_heavy_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292:SF1">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10292">
        <property type="entry name" value="CLATHRIN HEAVY CHAIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00637">
        <property type="entry name" value="Clathrin"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09268">
        <property type="entry name" value="Clathrin-link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13838">
        <property type="entry name" value="Clathrin_H_link"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01394">
        <property type="entry name" value="Clathrin_propel"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002290">
        <property type="entry name" value="Clathrin_H_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50989">
        <property type="entry name" value="Clathrin heavy-chain terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0168">Coated pit</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clathrin heavy chain linker core motif" evidence="9">
        <location>
            <begin position="344"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="551"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="700"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="847"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="993"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1142"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1288"/>
            <end position="1434"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="7">
        <location>
            <begin position="1437"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1617"/>
            <end position="1644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR002290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0568739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1726" mass="194415" checksum="E3577613C95EC15F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG47</accession>
    <name>A0A8T0HG47_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G091700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005875">
        <property type="term" value="C:microtubule associated complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051231">
        <property type="term" value="P:spindle elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00106">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000080">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969">
        <property type="entry name" value="CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47969:SF29">
        <property type="entry name" value="KINESIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="8">
        <location>
            <begin position="44"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="436"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="404"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="132"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0569458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="506" mass="55817" checksum="E50109102E4A0199" modified="2022-10-12" version="1">MANSAQSNRWGENGDDRRHTSWDAGTTCSKAVLGDSDIENQSSNIKVYVRTRPLSREELNKGESNCIHVSHDEKSLKVVEQGYGYNITTRSFQFDGCIGPEVHQQDVIKKVAMKKLLDKVLDGYSSTVMACGQTGSGKTYTMCGQEENQLCDIQGGDNGLIARSATYLFEAMKARGQNVSSGPKPFIMRASYFEIYTEQVNDLLRLDNAPRDVKWSSRDGYYVDNLLLVDCDTLDDVFSVLNEGSRNRKVGSHELNKDSSRSHCIMTLHIDSLCQVADDAPPITRYGRMLFVDLAGSERLKKSKSSGEMLKETGSINRSLFTLGKVISALSEGKKGDVVPYRESLLTKLLMDSLGGKSLALMIACVSPASSAIDETLSTLHYATCANNIVNAPAVNLDARDKIVLKLQREIAHLKEENHYLRSKLAEQNIEVDQFPSLGSANTPPSSATKRVRHSSQLPKSREKLPSELKGMEKYFSKDSTGSNKELAKELSGLSVFGNFQVTSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGH4</accession>
    <name>A0A8T0HGH4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G101500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGH4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.240.10">
        <property type="entry name" value="At5g01610-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036758">
        <property type="entry name" value="At5g01610-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007493">
        <property type="entry name" value="DUF538"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31676:SF10">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31676">
        <property type="entry name" value="T31J12.3 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04398">
        <property type="entry name" value="DUF538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141562">
        <property type="entry name" value="At5g01610-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="17164" checksum="AAC0D7EB2144B1ED" modified="2022-10-12" version="1">MATAVVTPPGGSVKPGESAVLVETGPESLQKATQLITEFGLPDGLLPLQDVVECGYNKETGYVWITQKKSIVHTFKEISKQVSYGDKITAYLDKGRLKKLTGVKAKELLWVSIVDIALEESDKEKIFFKSFAGIGKSFPVKAFLRGGASGAKNERAMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGI7</accession>
    <name>A0A8T0HGI7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G114300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd16448">
        <property type="entry name" value="RING-H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="196"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="343"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="54587" checksum="E234BA5157572D55" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGJ4</accession>
    <name>A0A8T0HGJ4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G189600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGJ4"/>
    <dbReference type="OrthoDB" id="2735536at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08958">
        <property type="entry name" value="FR_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000219">
        <property type="entry name" value="Cinnamoyl-CoA reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050425">
        <property type="entry name" value="NAD(P)_dehydrat-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366:SF852">
        <property type="entry name" value="CINNAMOYL-COA REDUCTASE CAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10366">
        <property type="entry name" value="NAD DEPENDENT EPIMERASE/DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="35109" checksum="808ED78F0AABC339" modified="2022-10-12" version="1">MASGKTVCVTGASGFIASWVVKLLLERGYIVRGTVRNPEKSKHLLELPGAGERLKLVEADLLKPGAFDSAVQGCDGVFHTASPFFHKNVTDPDAQLIDPAVKGTLNVLESCAKAKPRRIVLTSSVAAVSYTPKKEGASVVDESFFSDPDLCRKEQRWYVLSKTLAELAAWDYVKEHNLDMVTINPTMVIGPVLQSAMNTSTETVLEYLNGTTKTFANFCLGWVGVKDVAMAHILAYEKPEAEGRYICNERILHNGDVVALMKNLFPQYPIVAKDADDSPRVTPYNLSSEKVKKLGLNFQPLDDVLRETVVTLKDLKHLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI38</accession>
    <name>A0A8T0HI38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G170600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052979">
        <property type="entry name" value="Adenylate-forming_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33927:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="58394" checksum="BCBD103406F9914F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI89</accession>
    <name>A0A8T0HI89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G183400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0570727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="364" mass="41665" checksum="E89259DB3B7B2063" modified="2022-10-12" version="1">MICHSPTGDVKLGFQVPTMLSHVERVCCRFWCRWVLVVVWVLVMAMVYQRTSVEARLWQQMSFELVERVLSFLGAPDLCRCRAVCRRWDYLICTLRFGALCRENARGHPGYIVARVVEDTGGFYSESDGSEEEEEEDYTRFGWSILDVRLRLAADEGLVCEFRVFFELVVSLTVFNPLTKTTVALPFPPKHPGAKLKNGTLNFVVDETDNNFKIFFIHQCMMRMAPAGGSEGPEEIKRHDVMHIYESATGQWRSTTNPPLPKGQLGIGPFGSNVMFQGYCDLWYATNAMNLRVPTGRRKKLKMRKSNKKTWNETLSQSRKANGSGLPSQWIPQLIPPAGYTVCTCRKKISKGDRYNYRVQKWMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HII3</accession>
    <name>A0A8T0HII3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G168000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HII3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12399" checksum="6FE69F68ADE7E62A" modified="2022-10-12" version="1">MLTRLFYMYVSIGYFDDPFHIQFQGFFTRLSRQRGGEPIICTSLYDWSCGIWIGFHVFVRWHLPQGRVIDNCFSNLIVGNLSAQGFDGEEWCLTLCYHHSAFCDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ48</accession>
    <name>A0A8T0HJ48_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G188900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035886922" evidence="1">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="6124" checksum="FCE813FD37B08192" modified="2022-10-12" version="1">MFFLIPTLVLASLANCFYKEQRFCTIWSRNSWCVAARECQCAEKYFVFTSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMJ0</accession>
    <name>A0A8T0HMJ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG062800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMJ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6239" checksum="59670F97D965545D" modified="2022-10-12" version="1">MNGAVDVGFVLKASEVLVMFRNLLRTPHNVLNRHCGMTMLQGASYLTKFSTREAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN43</accession>
    <name>A0A8T0HN43_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein cereblon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein ohgata</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_VG075100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Likely a component of a DCX (DDB1-CUL4-X-box) protein ligase complex. May interact with pic/DDB1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRBN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15777">
        <property type="entry name" value="CRBN_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.20:FF:000005">
        <property type="entry name" value="Blast:Protein cereblon homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000007">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.40:FF:000015">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034750">
        <property type="entry name" value="CULT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255">
        <property type="entry name" value="CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255:SF4">
        <property type="entry name" value="PROTEIN CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51788">
        <property type="entry name" value="CULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="8">
        <location>
            <begin position="115"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="CULT" evidence="9">
        <location>
            <begin position="492"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="351"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="362"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0572195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="600" mass="66815" checksum="64BAD8EC99AA8521" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPZ2</accession>
    <name>A0A8T0HPZ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG126600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9625" checksum="988C1A451B3227E9" modified="2022-10-12" version="1">MSLAQLCFDARHPAERRCGSCEATVFGNESSIARSFREQVHRVTLHSCGYSNFSSFQQVFRLEAVFPFVVKYISLGVSSPTRQFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQT6</accession>
    <name>A0A8T0HQT6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG165000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF12">
        <property type="entry name" value="AT HOOK TRANSCRIPTION FACTOR FAMILY-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="382"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="128"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="457" mass="49285" checksum="641DB4FBFEBD0809" modified="2022-10-12" version="1">MSCRGFLQCMLRFTNFLLALVGGLIVIYSLWMVKEFHDEFPPPSPSPSLPPVVPPSPPPESPPQSPTPVPVPPPVPASPPEPAPEPSAAPTPAPTIAPTPAPTPAPSPLPTPSPTPAPTPAPTPSPTPSSSTTPASDVSPSSLTSAPDVSPPLPTSAPDVSPPAPPSPPSPPEPEPEPKPEPEPSSGPEPKPEPEPSDAPDVAPGPEQDLSIKRDGSSESVLQMFDLRYEQTRRPFLSLKKEKVKLPKWPAPWFIYAFLGVGVTTLLITCTGHIAAETSHNFCLSCYLCLQILLVVAQLILAGFLFFDEHWRQDLPDDPTGQLDKVEKFIEDNLDICKWFALGVLIVEALGLFFAMTLRAISIDSRRSGYDSDEEYAPRQPLLNRQNKQAAPQAGAPAGLPPSRTAVRNDAWSARMREKYGLDTTEFTYNPEESRGFAQQNQATPSTEDRPNRCTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRS3</accession>
    <name>A0A8T0HRS3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG181100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase zinc-binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="398" mass="45414" checksum="C0C2ED20E98F6D82" modified="2022-10-12" version="1">MGAIKEGHFFYYSTKRGYRYILDNQKKQPPLNRLLENAGHAKWERKRYYSKLWHPWVQRKIASMIWLTGSGGLPLADRRFRKKMCESGVCNMCSTGASETLEHFFMECPAVSEVWDRFRFLRALVAAEASADSVPARIDNIKTPWNILRVSLVWCLWCQKCGHDLRGGNFHIGVALFRAWQLTIQSGMGAWRELQNHISEPKTRRQMEKEAAFIKIWTHKGVFCKSDGRLKWQMAPHHQFLPKDLANLYRSFRGGTVRCDSGTDSSGNLLPSQVEDTLIAALAGNREERDKAEELADVILHQIFHDIARDVELEESREEAIPIGSMSVNQDDDEGAVPIGSRSEDQEEADEDLSSSDFEDDSSSSSLEGILPSDLQSPSELRLQARFWAAIERRSFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV87</accession>
    <name>A0A8T0HV87_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG279800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV87"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040229">
        <property type="entry name" value="At3g27390-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31133">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31133:SF12">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6005" checksum="52DE2167BAB03600" modified="2022-10-12" version="1">MQEDLLQCSLAFVVSIVAMFDEYTNNVLNLNEGSCLPRPRYRKGPPSTCTPGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY19</accession>
    <name>A0A8T0HY19_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Malectin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G051300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY19"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.430">
        <property type="entry name" value="Galactose-binding lectin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024788">
        <property type="entry name" value="Malectin-like_Carb-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45631">
        <property type="entry name" value="OS07G0107800 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45631:SF181">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12819">
        <property type="entry name" value="Malectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035865669" description="Malectin-like domain-containing protein" evidence="4">
        <location>
            <begin position="35"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="556"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="domain" description="Malectin-like" evidence="5">
        <location>
            <begin position="42"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0576052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="633" mass="68828" checksum="2BA0C3931705290E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYH3</accession>
    <name>A0A8T0HYH3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G040700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844">
        <property type="entry name" value="METHIONINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43844:SF2">
        <property type="entry name" value="SYNTHASE, VITAMIN-B12 INDEPENDENT, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12060)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="380" mass="42235" checksum="18F06028F5E69284" modified="2022-10-12" version="1">MPIPTELVGSLPRPIKLQDAYEAYDKGRITWEELQAAQDEAAADSIKRLEATGEAYVTDGEQRESSFATYPITDTLAGTGLAENLAGDGQYFAIFDDGHHRQLPRLTKGPFRYKTFASEFVGKNNAIATKPLKQAVISPSMMMLLYPLDGEIAGYPRTQFLDDVCDEVEKDIRQCFAAGAVRVSIDFTEGRLANKNDSRNPWTGKHMLQDFVDLNNRVLDRFSAEERRNIGIHTCPGGDCDSVHSKEVPYELLLERMFQMNAGYFLIQCASEEDKESVYKLCAQYRREDAKGVPQFCFIGVINPLNPKVETAEQVRDALLAAAKHIPANRLGATDDCGFSPFSRDLKPLHGSPDFARDIAMRKIAARVEGARLASVELGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYV1</accession>
    <name>A0A8T0HYV1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G074100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12444" checksum="8A61DBFE8ED048B4" modified="2022-10-12" version="1">MVPAWWWEDVELSTWRIEVLWRRGESLRSVEVSGGFGRGGGDGDRGGVLWRWWRCLDGSVWDWNPKERSGEGFRREGGLGIGLVVLRCLGWKTVLGGGTSVARIRGDRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0Y8</accession>
    <name>A0A8T0I0Y8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G063300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0Y8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="14844" checksum="54FE1A1ABADF49EC" modified="2022-10-12" version="1">MEPPKDPVEDCGITDELNVEAIWEDVKQKATALADDLGLAELASISDETSNASDDAGENPKAEELNSASHDAGENPNLNSNEPEGGQPSSNAGKEVVDKKKSTKPKKVFRPNRPKVTPEVESVMENILRSVFTPESKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2J1</accession>
    <name>A0A8T0I2J1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C-terminal processing peptidase</fullName>
            <ecNumber evidence="6">3.4.21.102</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G171600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>The enzyme shows specific recognition of a C-terminal tripeptide, Xaa-Yaa-Zaa, in which Xaa is preferably Ala or Leu, Yaa is preferably Ala or Tyr, and Zaa is preferably Ala, but then cleaves at a variable distance from the C-terminus. A typical cleavage is -Ala-Ala-|-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala.</text>
            <dbReference type="EC" id="3.4.21.102"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.102" evidence="6"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2J1"/>
    <dbReference type="OrthoDB" id="43580at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06782">
        <property type="entry name" value="cpPDZ_CPP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000023">
        <property type="entry name" value="Carboxyl-terminal processing protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.44">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060:SF31">
        <property type="entry name" value="CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32060">
        <property type="entry name" value="TAIL-SPECIFIC PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="7">
        <location>
            <begin position="260"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="557" mass="60256" checksum="29C8A34DC146D5B1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2S8</accession>
    <name>A0A8T0I2S8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G141800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2S8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046394">
        <property type="term" value="P:carboxylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01558">
        <property type="entry name" value="D-AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.10:FF:000010">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.10.10:FF:000011">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001594">
        <property type="entry name" value="Branched-chain-amino-acid aminotransferase-like protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050571">
        <property type="entry name" value="Class-IV_PLP-Dep_Aminotrnsfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743">
        <property type="entry name" value="AMINO-ACID AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42743:SF11">
        <property type="entry name" value="AMINODEOXYCHORISMATE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19798">
        <property type="entry name" value="Sulfotransfer_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="570" mass="63798" checksum="5817C41E5361D412" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5D0</accession>
    <name>A0A8T0I5D0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G013200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5D0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035830289" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7281" checksum="5166B913B8ADCAA8" modified="2022-10-12" version="1">MLLWSCLAIGWTFILVDMSFPAALWRKGPGRTQLCSRLEVSSPRFHYCDCNCDCGNALLYHVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5G1</accession>
    <name>A0A8T0I5G1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G016600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein neddylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019788">
        <property type="term" value="F:NEDD8 transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23794">
        <property type="entry name" value="UBCc_UBE2F_UBE2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000005">
        <property type="entry name" value="NEDD8-conjugating enzyme Ubc12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="10">
        <location>
            <begin position="28"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0578357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="20733" checksum="07E389ED19D63BBE" modified="2022-10-12" version="1">MIKLFSVKQKQKEDAQNNNGRPIKKQSAGELRVQKDISELNLAKTIAIHFPNGKDNLLSFEITIRPDEGYYQGGTFIFSFSISQVYPHEAPKVKCKTKVYHPNIDLEGNVCLNILREDWKPVLSINSIIYGLQYLFLDPNPDDPLNHEAAEVLRDNPRQFEQSVRRSMAGGYVGGTHFPRCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I859</accession>
    <name>A0A8T0I859_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-specific protease family C19-related protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G078000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I859"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040339">
        <property type="entry name" value="At1g16860-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33709:SF4">
        <property type="entry name" value="OS08G0230200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33709">
        <property type="entry name" value="OSJNBA0035M09.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="55066" checksum="77246E8E4FAFF21D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8K2</accession>
    <name>A0A8T0I8K2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G135200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584:SF369">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11584">
        <property type="entry name" value="SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1282"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="451"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="484"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1025"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="181"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="731"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="786"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="875"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="226"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="732"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="806"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="905"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1054"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0579924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1336" mass="144349" checksum="9413D0BFED5507DF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB95</accession>
    <name>A0A8T0IB95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G121700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11537" checksum="E63D82FCFDAA91B6" modified="2022-10-12" version="1" fragment="single">FISLIGGHLLVSLQLSLTFQTYFLLLTASLSKYGCMTRIRYNKSYSRVLMSTVPRRMAQNVGYYYFIALYIRLISLGPQYRSLPSPTDVSCGSVPGRTLKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC65</accession>
    <name>A0A8T0IC65_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-ketoacyl-CoA synthase</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G145600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC65"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000028">
        <property type="entry name" value="3-ketoacyl-CoA synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012392">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013601">
        <property type="entry name" value="FAE1_typ3_polyketide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31561">
        <property type="entry name" value="3-KETOACYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08392">
        <property type="entry name" value="FAE1_CUT1_RppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036417">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="FAE" evidence="12">
        <location>
            <begin position="108"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal" evidence="13">
        <location>
            <begin position="414"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0580083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="58918" checksum="5B9F7FB174C30C8E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFI2</accession>
    <name>A0A8T0IFI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G063500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="18325" checksum="EAF4C254C0262635" modified="2022-10-12" version="1">MIFKLGFVTRVREIVRVLRGLPPDDAVRQRTLAINEQLARLRATRIAQEKQREQAALRQVQFVIEEMEQLKESLSAAEEAAVEFVNQIGDHAQAQLEDEWEKKTETLMAEVMVQQIPTTGEPTGYKADVPVASSFPRESSQEPSVVSKTRTIVVEARVTPPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGD7</accession>
    <name>A0A8T0IGD7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G024500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGD7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000554">
        <property type="entry name" value="Ribosomal_eS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047861">
        <property type="entry name" value="Ribosomal_eS7_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11278:SF0">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN ES7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01251">
        <property type="entry name" value="Ribosomal_S7e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00948">
        <property type="entry name" value="RIBOSOMAL_S7E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="71"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="283" mass="31827" checksum="3C75AAE2C8D45FC8" modified="2022-10-12" version="1" fragment="single">PGCQCVKKGKLVARRRNPNAATADARQRRGRGRGLQGRGAGERGSRGGETKAAEGVSAASLSLAHSHPCVERLHHQDPRRSLSRRQAAMSFTARRKIQKEKGQEPDEFEESVAQALFDLEASNSELKSELKDLFINSAKEVDVSGNRKAVIIHVPYRLRKAFQKIHARLVRELEKKFSGKDVVVISTRRILRPPKKGSAVNRPRSRTLTSVHEAILEDLVYPSEIVGKRVRYRLDGSRIMRVYLDPKERNSTEYKLETYAGVYKKLTGKEVTFEYPIQEATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGX4</accession>
    <name>A0A8T0IGX4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 14 C-terminal Fig4-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G009300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAC14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGX4"/>
    <dbReference type="OrthoDB" id="5574975at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070772">
        <property type="term" value="C:PAS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006661">
        <property type="term" value="P:phosphatidylinositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000169">
        <property type="entry name" value="protein VAC14 homolog isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026825">
        <property type="entry name" value="Vac14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021841">
        <property type="entry name" value="VAC14_Fig4p-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023:SF0">
        <property type="entry name" value="PROTEIN VAC14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16023">
        <property type="entry name" value="TAX1 BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12755">
        <property type="entry name" value="Vac14_Fab1_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11916">
        <property type="entry name" value="Vac14_Fig4_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="5">
        <location>
            <begin position="92"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Vacuolar protein 14 C-terminal Fig4-binding" evidence="7">
        <location>
            <begin position="429"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="703"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="723"/>
            <end position="732"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="750" mass="83451" checksum="51DDB18D29171A2E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHB0</accession>
    <name>A0A8T0IHB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G048200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045203">
        <property type="entry name" value="RanGAP1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46761">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46761:SF2">
        <property type="entry name" value="RAN GTPASE-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="473" mass="51369" checksum="0DA8F1352F130DDC" modified="2022-10-12" version="1">MLLNRFHVSPAGGMWFVVGILLWLFVAVVYRIYFRPETMTRMEDVPVESLFDVSGGTRAFLTKEKAEELLKQLLDADNAYTRIRLGNWSFGIDAADVAARALSSMKSRLVDVDLADIVAGRPEAEALKVMSIFSSALEGSQLRSLNLSDNALGEKGVRAFSSLLKSQKSLEKLYFMNNGISEEAAQAICELVPFSGNLRVLHFHNNMSGDGGAQALADFVRTATKVEDFQFSSTRVGVDGAIALVEALRTGKSLKRLDLRDNMYGPEGGLALAETLKLHPELQEVYLSDLGLEDEGATAVLKALAEVGSHVEVLELGGNEITEKAAPALVSCIRAMKSLRRLVLSENELKDKGAVAVSQALLEGHESLEVLDLSENMLGRIGAVAAAQTAAKKKSFKSLNLNSNYISEGGLEVLKEVLSKGATGLKVLGSLDENDEDGEDEEETGDEEEEEDDDEERECPCCIGKTRFEDLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHM6</accession>
    <name>A0A8T0IHM6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G124300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004864">
        <property type="entry name" value="LEA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044839">
        <property type="entry name" value="NDR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234:SF4">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03168">
        <property type="entry name" value="LEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Late embryogenesis abundant protein LEA-2 subgroup" evidence="7">
        <location>
            <begin position="110"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="239"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0583294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="263" mass="29364" checksum="8318BFD6851F54D5" modified="2022-10-12" version="1">MGYAEYAEAEQRAPVVVQEVRYYLLPPDTVHDLPLYRPRRRVVTVGTIVAPILVLFSCLLLAGAAFVFWPSQPEIELEHWKLNGINFDSKEEGRSIIPAVYVNISLDVILQIKNPNFVGIYYDFLKVEILYRGSYLGDAKLKGGHILARRAVPVPAILNLEAREILENAVELLADIARGEVPLTTHIKIVGDVDLQAVRPHIDVNLNCDVVVDPRTKLVIREFCGLDIFEGTQLRRRQSSAGAANHRSNSSDDQLSGQAIMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ44</accession>
    <name>A0A8T0IJ44_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G094100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10752" checksum="954FADC65FE1CBCA" modified="2022-10-12" version="1" fragment="single">GAPLSPVTQPTGTELQSSHPRQASSNASTLRVPCRNWPPLRPSLHLPISTPSPLPLAIAPLRGGIPEHSASRFEKLPCRREGDKRKAKQVAECLRMETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL14</accession>
    <name>A0A8T0IL14_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G151100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16806" checksum="9FF7FFC404FD8C58" modified="2022-10-12" version="1">MEDHNHILHDEQTILLLFIEDRQQLSLRAFVDKILLFFYVAAGVDTMNFEEKSKWFFSHDAEEFVDYGSNLVLLGQGSITRDMATLALMQKLRSVSKTASKVACHIAKPIQVVYELDKLSNVDSSLYHLFEMCFGVKAKDMIQALEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILU9</accession>
    <name>A0A8T0ILU9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G163700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the REI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030687">
        <property type="term" value="C:preribosome, large subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041661">
        <property type="entry name" value="ZN622/Rei1/Reh1_Znf-C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040025">
        <property type="entry name" value="Znf622/Rei1/Reh1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022755">
        <property type="entry name" value="Znf_C2H2_jaz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182:SF8">
        <property type="entry name" value="CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13182">
        <property type="entry name" value="ZINC FINGER PROTEIN 622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12756">
        <property type="entry name" value="zf-C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12171">
        <property type="entry name" value="zf-C2H2_jaz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="68"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="102"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="135"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0583796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="406" mass="45689" checksum="89FB7A18F4497997" modified="2022-10-12" version="1">MRGLACNACNEVFADEDAQKQHYKTEWHRYNLRRKVAGVPGVTEALFNLRIEALEAEKKKKEGERLLYKCALCNKEYSTEKAHANHLQSKLHVTRAASADAPADAGVAGTRPAPQKASAVSLEATRTQNGKAVVEEESDDEWEEVDGEDVEEDGDTVAEMEEAGPSDDPLSGHWEPSDCLFCGRNHADFEACIEHMHRDHGFFVPDAEYLKDPVGMLTYLGLKITKGFMCLFCDERGKQFHSVEAVRKHMINKSHCKLRYGDGEGIAEEELEDFYDFSSSYKTAESSQVLALHDGANSLVSLASGGHELVIKSGDDEGLVKRIGSRDMARYFRQRPAPTDNRNGMMVNALVARYRSMGLATQEQKWRLRNKPEEQQRKASQRAEYIRSKIALKNNVIRNLPRNCEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMZ0</accession>
    <name>A0A8T0IMZ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP cyclohydrolase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G193000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109:SF7">
        <property type="entry name" value="GTP CYCLOHYDROLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="GTP CYCLOHYDROLASE I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55620">
        <property type="entry name" value="Tetrahydrobiopterin biosynthesis enzymes-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="7">
        <location>
            <begin position="71"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="GTP cyclohydrolase I" evidence="7">
        <location>
            <begin position="347"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0584201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="542" mass="58590" checksum="039937652E198D10" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPZ2</accession>
    <name>A0A8T0IPZ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G259800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="154"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="548" mass="63021" checksum="ACDD74D7AC8BA88A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQJ8</accession>
    <name>A0A8T0IQJ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G226100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11241" checksum="D366D50B21DC6FFB" modified="2022-10-12" version="1">MVLQHHHNHHHQHCVDEHQGGCFNYVGDRRVCAGMGHAKDRHQMAGSWDSGNEEVMMMEAKLVLGLPFTEYAKTGGVLGPNLGESGDAFNVTVKVSLGECLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRT5</accession>
    <name>A0A8T0IRT5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G035900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11037" checksum="45B81EAB620FE5D2" modified="2022-10-12" version="1">MLTSPATTSGTPTRLRNLQRRSGYILTLSTQHAIHASIARFKQRQLQFQTQPKQSSRLIPAIPQTSSASPSRINTRIQAPPIRTTLPRAPGSTPPRKSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITG6</accession>
    <name>A0A8T0ITG6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G060000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002999">
        <property type="entry name" value="Tudor"/>
    </dbReference>
    <dbReference type="SMART" id="SM00333">
        <property type="entry name" value="TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63748">
        <property type="entry name" value="Tudor/PWWP/MBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tudor" evidence="1">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="219" mass="24450" checksum="F6E907C6FB6942CD" modified="2022-10-12" version="1">MPAGTGSGASTARKGDAISVFWPLDNTWYHGRIDSFDAVSGECEVLYDDGERQGLNLFTTKYKFEVKHGVRVLELIDLVRADHGNVSKQLKHIGDALLSMSDKLPSAGCCSSRQGWWRDWCADIKSAVKAGSVIALVKVTYDLACQIRLRGVDASDCRDIVSTDWWNEKEGRELWFERLRSAKTCEDLVVCVDLLKIKAVDWKKARKLFPNSDDSSESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU87</accession>
    <name>A0A8T0IU87_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G110800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU87"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14507" checksum="89BA71041BDD8115" modified="2022-10-12" version="1">MLQLAPDHINRIQRLVTGDKVLNSGLRIRVSSAQHTCFLNHLLTYFLSKVAPVKLPTLMLSREVRFSTLILSISIYGVFHISTSPISHHRVTLHLPLTRIPNVVKKVGLGWPPRVTTMSFVHNVNRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVS7</accession>
    <name>A0A8T0IVS7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G152900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVS7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8488" checksum="FD5FE01F35B9AA5E" modified="2022-10-12" version="1" fragment="single">WEARALSGYGSKKVYTTSSVGLQGRRVRSSHTSTRIAQLENIRRFCFRIAAWVATDCSRHTSNRCSSRASSPGPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW38</accession>
    <name>A0A8T0IW38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G136800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="215" mass="24727" checksum="2B3C6ECFA67F80DF" modified="2022-10-12" version="1">MECRKVEEQALDEYEVHVAFEGRSSFHQNLRFALLASSWLPGILVWSVLHLLLVFVATLFFILVVIYMLIMDIATQLVLVPMVYIFIALCDIVVLIVDTLRYIFVTIRVIVSCEATPGEATKFAYEHIGGIRLFRYVRFVVFENEGNGRIRWLMPFLLSVEIIKDCCSGPSERGEAREPGLGPGEPRPPREEPFRLQLKRWCEEIVPCYDVLLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWI3</accession>
    <name>A0A8T0IWI3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G134800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="183" mass="19786" checksum="3B1A12C0F00BAD48" modified="2022-10-12" version="1">MISMAKPKATEIPTWLEAVPFREQALSAVPCIRKPHASRNSWTWAGTTSLTKLSVALAKPPWAWPSKNGSADAPEFSSMSTISTTFPSSCSLFFPLVLSLVFSLIFFLIFSLVSSLIFSSFSSTFSFTASCSSVNFCTSTFVTRISLSFTRSSLASMRSMSSKLISASLSLPSSPKTSASIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWI5</accession>
    <name>A0A8T0IWI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G154900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5913" checksum="8CBAB88FAD4EB26B" modified="2022-10-12" version="1">MAAGMENVAVDDQESNAELVLFQVKECYVYMIPPRKSAASYNADEWDINKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWM2</accession>
    <name>A0A8T0IWM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="11">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_2G169200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="11"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18015">
        <property type="entry name" value="DEXHc_RecQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18794">
        <property type="entry name" value="SF2_C_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001215">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001544">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="entry name" value="HRDC domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018982">
        <property type="entry name" value="RQC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF105">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09382">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00956">
        <property type="entry name" value="RQC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="15">
        <location>
            <begin position="126"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="16">
        <location>
            <begin position="326"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="HRDC" evidence="14">
        <location>
            <begin position="638"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="619"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="746"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="861"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="621"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="758"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="876"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="890"/>
            <end position="909"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0587502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="919" mass="101531" checksum="4565A6EC118099B4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX10</accession>
    <name>A0A8T0IX10_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G157300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805288" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8805" checksum="D9A45ECA12A294A7" modified="2022-10-12" version="1">MLALDLLQVVLVHVCFFRLDRGESTRDVLSLFNKPRQIVCHCKYCSSGDFRDCRGAVSLNDCSLLKPLSINNVTAILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXB9</accession>
    <name>A0A8T0IXB9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G194100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050416">
        <property type="entry name" value="FAD-linked_Oxidoreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973">
        <property type="entry name" value="BINDING OXIDOREDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G17690)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42973:SF39">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035785171" description="FAD-binding PCMH-type domain-containing protein" evidence="6">
        <location>
            <begin position="28"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="7">
        <location>
            <begin position="73"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0587825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="501" mass="53824" checksum="12F53CABB7620795" modified="2022-10-12" version="1">MGRFAFAKVLAGVLIVLAFICSVPVAAYNEQPRIGRKLAATTLQQCLATGGARTAFPGSSDYNNARVDYNKRTNYAPAAFVFPTTVAQVQNAISCAKQVGVGIVPRGGGHSFEDYSLGGRDGVLVVDMVGFKQLSYNSGAKTAIVGAGWRLGPLFLALWNAGKVTIPGGNCPTVGVAGHALGGGWGFSSRKFGMVSDNILEAQLVTANGTLVTANANQNSDLYFALRGAGATSYGIVTQFTFRMNDVSSPVTHFKYTWSTKSLQFQNFKAFQIWGVNVPAEISASFYMDPSGTSWLEGTYLGPKTSLPPLVQSFLSNAAANPTTSVEQLDWIHLILVNAGYPSNTDPNTLNNVPFPLNTFKAKSIFVNAPGMSDAGINAMINAMRAGNNNAYFIYDLYGSQSAINKVATGATAFVHRTSLYSIQMVAYWSNANDAVGQTNYVSNYFNAVKPYATGEAYQNYIDRNMGLSAYYGSNLNALITDKKKWDPQNVFNFPQSIPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXS4</accession>
    <name>A0A8T0IXS4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G250600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXS4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035940937" evidence="1">
        <location>
            <begin position="35"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="13676" checksum="2A009B5BE9BDACAA" modified="2022-10-12" version="1">MAAKYSSGSSSGASTMRATLVLLLLLGAVVAAHGRKVSCVNKCPKPIKCNGILVDVDATVIVDIDLTVKVDVTDITDVLLSGTYLVPGDVTELVVIYVDGYLKVTVGKVLTIIGGILQTLVGLVLGLFKCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1R7</accession>
    <name>A0A8T0J1R7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Domain X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G024300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1R7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006315">
        <property type="term" value="P:homing of group II introns"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090615">
        <property type="term" value="P:mitochondrial mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024937">
        <property type="entry name" value="Domain_X"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33642">
        <property type="entry name" value="COX1/OXI3 INTRON 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33642:SF4">
        <property type="entry name" value="COX1_OXI3 INTRON 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01348">
        <property type="entry name" value="Intron_maturas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Domain X" evidence="1">
        <location>
            <begin position="118"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="39181" checksum="5D5540B79C9B6C42" modified="2022-10-12" version="1">MAMARAMQAARVLLRRPACSSTLLPEFHQVDGRILAPLRSCSSLLGTNSSDFAGFEGEFGDGWRAGGLKRSMHTDVSAARVGRRAARVEESEDDMNFSEEDEPREEHVMVRPFEAPVALEAPVKLLYELLQKKGFIDEKVRPLPIDQVASQDDHRIVAWYRSIGIGLLRYHSYCDNLSKVRAIVNYLLRWSAIYTLAKKHKSSSSQIIAKHTKSLVITKNGKTLAAYLTPTEISEYKKKFIVDLDPTPPGELIDMLFARLVRKKLLAERCAVKGCKERNVEMHHIRQIEKAGGRHKVRSAREAQILEGIKAVQSALNKKHIPLCVRHHDDLHMGKVFIDELDMNVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2M9</accession>
    <name>A0A8T0J2M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G280800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="31"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1197" mass="136767" checksum="CBA739189387DCCC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2R7</accession>
    <name>A0A8T0J2R7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G284700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2R7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="16382" checksum="A914028CE5E3DACE" modified="2022-10-12" version="1">MARHRDWRRTIHDNGQGLRHYTPKVEMNWNWNWQDRKTVRFRRPCCSSACCIYAMLGKHSSLHQLSLEQLRCIGLDVLSTSCALPLRSSIDQLNHLLDDICFGVELVDSKCSELRCCGVALKIEFSPVRSFVWKLLELCES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3C9</accession>
    <name>A0A8T0J3C9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G098100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase GT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3C9"/>
    <dbReference type="OrthoDB" id="2012966at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11299">
        <property type="entry name" value="O-FucT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11350:FF:000011">
        <property type="entry name" value="O-fucosyltransferase 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024709">
        <property type="entry name" value="FucosylTrfase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31741:SF1">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31741">
        <property type="entry name" value="OS02G0726500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009360">
        <property type="entry name" value="UCP009360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="495"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="551"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0590420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="572" mass="64732" checksum="A3219CA7B3A25146" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4A8</accession>
    <name>A0A8T0J4A8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">E3 ubiquitin-protein ligase TRIM37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G094600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016235">
        <property type="term" value="C:aggresome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005164">
        <property type="term" value="F:tumor necrosis factor receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070842">
        <property type="term" value="P:aggresome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051865">
        <property type="term" value="P:protein autoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19756">
        <property type="entry name" value="Bbox2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16619">
        <property type="entry name" value="mRING-HC-C4C4_TRIM37_C-VIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053003">
        <property type="entry name" value="TRIM_RBCC_E3_ubiq-ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36754">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36754:SF2">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00643">
        <property type="entry name" value="zf-B_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57845">
        <property type="entry name" value="B-box zinc-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="197"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="B box-type" evidence="7">
        <location>
            <begin position="270"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="460"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="716"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="841"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="719"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="742"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="845"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="876"/>
            <end position="888"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0590375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="942" mass="104810" checksum="CD823ADA0A9C0C41" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4I1</accession>
    <name>A0A8T0J4I1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G129300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4I1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14158" checksum="799C179C5C1B4E2C" modified="2022-10-12" version="1">MAATLLSRAMEYATPLPCRSPKSLQSFLNMKALISDVNNGLYDLKCVIATRMVAPSCKSNTPPRVKLPSTPDTPKTIHCRRHGLSQRVRAATRLPRAMEYATPHPQQKDLNHEGLKAPSHESTDLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4V0</accession>
    <name>A0A8T0J4V0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G137600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxin-11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4V0"/>
    <dbReference type="OrthoDB" id="411017at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016559">
        <property type="term" value="P:peroxisome fission"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044375">
        <property type="term" value="P:regulation of peroxisome size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008733">
        <property type="entry name" value="PEX11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652">
        <property type="entry name" value="PEROXISOMAL BIOGENESIS FACTOR 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12652:SF17">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 11B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05648">
        <property type="entry name" value="PEX11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="249" mass="27599" checksum="1EF3791035F23477" modified="2022-10-12" version="1">MDLKQKDTIDKLVIFLAKRDGIDKVVKTLQYLGKLAHYNLESKNPVLAARYKNLEVAAGLSRKVFRGGRSLAGFSALRTATYPDLTIQLLTIFGYSGEMVYWLFDHFTWLSKVGVLNSSVSDTTMYISAFGESVAYIFFITIDVILIKRGMNAEVGLKKQLAKLEAGSEHGEEEDSTNAEQVKILKSKIAAIKMQRVMSVMSIVARTSDLFIALSVVDPNPFVSHTVTLCLSGLASAWAGWYQQWPAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6F0</accession>
    <name>A0A8T0J6F0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G095200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6F0"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052583">
        <property type="entry name" value="ATP-helicase/E3_Ub-Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048695">
        <property type="entry name" value="SHPRH_helical_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45865">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21324">
        <property type="entry name" value="SHPRH_helical-2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="347"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="447"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0590383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="667" mass="73010" checksum="AD7324C100DAE72C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6X9</accession>
    <name>A0A8T0J6X9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phospholipid/glycerol acyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G171700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6X9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753:SF48">
        <property type="entry name" value="PHOSPHOLIPID_GLYCEROL ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22753">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="2">
        <location>
            <begin position="478"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="722" mass="79897" checksum="AC238F01A081BCD8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBQ9</accession>
    <name>A0A8T0JBQ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G322300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8845" checksum="717CDA8D8F4DA96B" modified="2022-10-12" version="1">MNPCWTDSLQTPQQDSFKSIKKGYGHVGLLLHYDEASKFGVIFLGTRNPRQAHRFVPWYGTDRKAFQPLAQLKPDPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBT3</accession>
    <name>A0A8T0JBT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G316400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MBF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBT3"/>
    <dbReference type="OrthoDB" id="10253401at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.40:FF:000018">
        <property type="entry name" value="Multiprotein bridging factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013729">
        <property type="entry name" value="MBF1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245">
        <property type="entry name" value="ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10245:SF123">
        <property type="entry name" value="OS08G0366100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08523">
        <property type="entry name" value="MBF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="lambda repressor-like DNA-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="6">
        <location>
            <begin position="84"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0593257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15438" checksum="EC0449A332FEDF64" modified="2022-10-12" version="1">MADLRQDWEPVVVRKKAPTSGAKKDEKAVNAARRSGAELETIKKFNAGSNKAATSATGLNTKRLDDETDVLAHEKVSGELKKNLMQARLDKKYTQAQLAQLINEKPQIVQEYESGKAIPNQQIITKLERILGVKLRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBV7</accession>
    <name>A0A8T0JBV7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G318600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015112">
        <property type="term" value="F:nitrate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042128">
        <property type="term" value="P:nitrate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17341">
        <property type="entry name" value="MFS_NRT2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000053">
        <property type="entry name" value="Nitrate transporter 2.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044772">
        <property type="entry name" value="NO3_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23515">
        <property type="entry name" value="HIGH-AFFINITY NITRATE TRANSPORTER 2.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0534">Nitrate assimilation</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="8">
        <location>
            <begin position="62"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0593287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="521" mass="56452" checksum="473752F4A38A1403" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBY8</accession>
    <name>A0A8T0JBY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G251300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12116" checksum="41EA0BEB5C77AD68" modified="2022-10-12" version="1">MVMPFTHPKPVLHSTFPDSSTKFSYHNSSPSTFYISNTTPETATNPSTHIASNSQPSLQHQKLKTIHSISRNANPTSNPSITKTEATTQTTTTAPNSQHRKDTKTTTKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCI4</accession>
    <name>A0A8T0JCI4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transcription and mRNA export factor ENY2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Enhancer of yellow 2 transcription factor homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G337200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Nucleus</location>
            <location evidence="1 11">Nucleoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ENY2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCI4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071819">
        <property type="term" value="C:DUBm complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070390">
        <property type="term" value="C:transcription export complex 2"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.140:FF:000001">
        <property type="entry name" value="Transcription and mRNA export factor ENY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03046">
        <property type="entry name" value="ENY2_Sus1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018783">
        <property type="entry name" value="TF_ENY2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038212">
        <property type="entry name" value="TF_EnY2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12514">
        <property type="entry name" value="ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10163">
        <property type="entry name" value="EnY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0010">Activator</keyword>
    <keyword evidence="4 11" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 11" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="10 11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="6 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0593537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="33523" checksum="9698A2199F063B16" modified="2022-10-12" version="1">MRTSGRGDEGEPKPKPPPRGGDRGVGWGGLGLQERTAPCTACSIAIAIASLYLPLLLGLPVCLCTLAPPPPPHTAAGLLILRLHSRAIAIPRSLARTHARTRCDVACACARSLCALLLLLLFLLLLLVVRVFLRERNCWQRSRLIDGAAETPLLPFLLRAFAPLPLFRISSVVAASLVLPFPLCAPRPAQPSPAMRASVIRPPTPDGEEERDPEPTLQEIINIKLIESGEKERLKELLRERLIECGWRDELKAQCRAFTRKKGRNNITVDELVRTITPKGRAMVPDNVKAELLQRIRAFLLTDPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCL3</accession>
    <name>A0A8T0JCL3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G311500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015165">
        <property type="term" value="F:pyrimidine nucleotide-sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007271">
        <property type="entry name" value="Nuc_sug_transpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00803">
        <property type="entry name" value="nst"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10231">
        <property type="entry name" value="NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04142">
        <property type="entry name" value="Nuc_sug_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="379"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="67"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0593205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="47314" checksum="1AE7D1D46C1600AC" modified="2022-10-12" version="1">MRKRSGAVTESLDKHHEITSRKQRTRRPRSSASNCRDSRGLEELGSISRRRRDHSAHRREEGEKTSHKARARERAKHATQEGMATARERHATARLDSAPAAMADASANAQAAADASKQRVRAAMCMVLLTLQYGVQPLISKRFTGKYVIMTSAVLTCELVKCAAALVFMARDGTLWKLPKEWSFVDSLKASASPAAIYALQNTLLQLSYRNLDSLTFSLLNQTKLVFTAVFMFIILGSRQTKQQIGALFMLLIAAMLLSLGKTAPQQRGKQVAWESTLWLGIIPIISASVLSGLASTLCQWAAQVKRRSTYLMTLEMSTYGSLVLLISMWWSPDGVSIQKRGFFYGWTLLTFIPVIFNAFGGILVGLVTQYSGGIKKGFVIVSALLVTALLEVVVEGKPPSSYAIAALPLVVSSTIIHQNYPYKAKPKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JFQ1</accession>
    <name>A0A8T0JFQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G334200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JFQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11235" checksum="21A67579C4DD754F" modified="2022-10-12" version="1">MLLKTQGNLCHELCKPHHSQNPDSFNRTVPEPHPSTKFCSVNSTQRGEFRLVKCGEAQSGVGIDESIIRGRTGGQSQRRPVDEACEWDCCAACEVESCCSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4K3</accession>
    <name>A0A8T0G4K3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G052100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4K3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007877">
        <property type="entry name" value="DUF707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210">
        <property type="entry name" value="OS06G0731900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210:SF47">
        <property type="entry name" value="OS07G0564800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05212">
        <property type="entry name" value="DUF707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="451" mass="51430" checksum="C995F3382451C7EA" modified="2022-10-12" version="1">MKGASCSVMALKPSLSFIPFLMLGFFFGFLSALSLSQQFCYTNSWHSPITDPSTVIKSQSEASNLVQEDNTTIKPSFGEETVRVIAEPVCPPCEERFEKLSRGAKEFLQTDTIVSNGILHHNCSTSGTDESRFNSSGSVCRSPTLVDKLPQTFIHKTTDFHFHNLVGTPENDVKNVPKNLLALAVGIKQNMSVDAIVKKFPKEHFQIVLFHYDNTVDQWNQFEWNNRVIHVQSTSQSKWWFAKRFLHPDMMAPYEYIFVWDEDLGVENFDPMKYIEIMKRHELQISQPAVDGATSWPITIRRYWTGKEVHKHTMWEGLIDNCTLSKVTPPCAGFVEIQAPVFENKAWRCVWHLIQNDLVLAWGLDFQLQACIDGPPHEHIGIVDTQWIVHNKIPSLGSQGAEADNPKRLRGEVIARSNYEWTENKRRWAESLESQKTKFHSTDGSPNSSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6V7</accession>
    <name>A0A8T0G6V7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiol methyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G135600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6V7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF11">
        <property type="entry name" value="THIOL METHYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0554993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="268" mass="29522" checksum="81C215D6E5D491AE" modified="2022-10-12" version="1">MNSTTEDATHGIGAPMELPTMNSTTEDATEHGSMELPFHMRLKSVELSRMRELTGTQPMETAWEQCWQEGITPWDVQGVTPVVAQLLRANQLRDGKALVPGCGSGYDVVAMGSPTRSVIGLDISPTALHQAHQLAHNSPHAAQFVEFQNADFFSFSPPFKFDLVFDYTFFCAIDPSLRPRWAHKMADLLAVDGELITLMFPLDDHEGGPPFAVSMDAYEKVLSPCGFRLVSCNSEIPSLNNRTGLEKLGRWERAVPKLDDSEVTNGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G754</accession>
    <name>A0A8T0G754_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G045200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G754"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="12138" checksum="8A153ADBD7FEEA55" modified="2022-10-12" version="1" fragment="single">SFPRKEINKKKTVSLDIDLPLRLEIASRNTKHDHKNSPEWPLVKILHLDSTIQAHRLQNCNSKLINYDRLTKTHQQPENSKRIKQYQTCGGFDHFSNTSSTQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7A9</accession>
    <name>A0A8T0G7A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">7-dehydrocholesterol reductase</fullName>
            <ecNumber evidence="17">1.3.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Sterol Delta(7)-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_12G121000</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERG4/ERG24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.21" evidence="17"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7A9"/>
    <dbReference type="OrthoDB" id="5326588at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047598">
        <property type="term" value="F:7-dehydrocholesterol reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016132">
        <property type="term" value="P:brassinosteroid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006695">
        <property type="term" value="P:cholesterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001171">
        <property type="entry name" value="ERG24_DHCR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018083">
        <property type="entry name" value="Sterol_reductase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257:SF38">
        <property type="entry name" value="7-DEHYDROCHOLESTEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21257">
        <property type="entry name" value="DELTA(14)-STEROL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01222">
        <property type="entry name" value="ERG4_ERG24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01017">
        <property type="entry name" value="STEROL_REDUCT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0152">Cholesterol biosynthesis</keyword>
    <keyword evidence="4" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="12" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="127"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="395"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00038851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00039984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00042688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0554811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="454" mass="53403" checksum="E89F8451DC0F0E1D" modified="2022-10-12" version="1">MGRRSRTPTRKNYIEMSSYQKDPALSAHSKRVNYIAMGCLIFLGPIIVVCLWHTIVNLDGSALNMWKYWKTYNFEGVRKIWPMPSFYACKLIVFFAVFEALLQVYVPGERHIGIVSPTGNRPMYKKNGFTCCVITIFVYYFAYKEKHFNPAGVYDHLGEIYSALIVISMIVCCLVYLKGHTYPSSTDWGSCGNPLIDFYWGMELYPRIGRDFDLKLYFISRFGMMSWACLVISFVIKQWEQKGKVADSMFVSSVLQLAYIFKFFWWEGGYLNTLSMMHDRAGFYTIWGAMVWLPAVYSSPVLYLVQHPVQLGRWVSIYVFFAGLLCIYTQYSIDWQRQEFRETHAKARVWGINPVKIQAHYVTEKGEHKQTLLLASGWWGLARHVHYIFEIGSCFFWSIPALFTHTSPYFFLLFLTFFLVDRVERDDRRCKAKYMKFWDIYRKKVPNKIIPLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8N5</accession>
    <name>A0A8T0G8N5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">lipoyl(octanoyl) transferase</fullName>
            <ecNumber evidence="3">2.3.1.181</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G179900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="3"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000063">
        <property type="entry name" value="Octanoyltransferase LIP2, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010925">
        <property type="entry name" value="PRK14345.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993">
        <property type="entry name" value="OCTANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10993:SF15">
        <property type="entry name" value="OCTANOYLTRANSFERASE LIP2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21948">
        <property type="entry name" value="LplA-B_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="9">
        <location>
            <begin position="34"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="79"/>
            <end position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="148"/>
            <end position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="8">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0555583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="230" mass="25560" checksum="78AB94DBCF510DD1" modified="2022-10-12" version="1">MAGLRRLEVWRMRELINYAEALHLQSQLVERRRRGGADVLLSLQHPPTFTVGKRRTVHNMLASPQELHAIGAELHMTERGGDITYHGPGQPVLYPILGLREMRVGVRAYVEGLEDVMVEVCKMHGVDARGRMEKETGVWVQGLRKIGAIGVRVSSGSITSHGLAFNVDPNLAHFDHIVPCGIRDKEVTSLRKEVSPVVPDVEEVTEQLIQCLAKQFGFAAVVDMEPPSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8Q8</accession>
    <name>A0A8T0G8Q8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fertilization-independent endosperm protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G029100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat ESC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8Q8"/>
    <dbReference type="OrthoDB" id="7318948at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051243">
        <property type="entry name" value="PcG_WD-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10253">
        <property type="entry name" value="POLYCOMB PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2 6" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="6">
        <location>
            <begin position="176"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0553662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="376" mass="41887" checksum="F34CA5FEA424E805" modified="2022-10-12" version="1">MALKPAEGFGTEPVVGEVVVDSKRARKYEMTTRFQECKKPLYAICFNLIDARFYRVFASAGGNKVTVYQCLPEGGALAVLQTYVDEDKEEEFYTVSWAVGKDGSPLLACSGSKGVVRVVDCESETLQRSFVGHGGSVNELRTQSLKPCLVASASKDESIRLWNVDTGVCVLVFAGAGGHRNEVLSVDFHGSDILQMASCGMDGSIKIWSLRDYWKFVEMSFTWTDSVSKFPTKHVQFPMLTALVHNNYVDCTRWLGDLILSKSVDHEIVLWEPLQYKVAGSTENEGKVDVLQKYPVPDCDIWFIKFSCDMHFENLAIGNREGRVFVWEVQSSPPKLIAKLSHPQCRSPIRQTATAHDGSTIMCCCEDGSICRWDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8U3</accession>
    <name>A0A8T0G8U3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G032400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8U3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="54"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="462"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="738" mass="83122" checksum="BF682293E593CF47" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G975</accession>
    <name>A0A8T0G975_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G159300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G975"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="998"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1039"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1078"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="1134"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="8">
        <location>
            <begin position="954"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1179" mass="133610" checksum="302FC0A527D17D54" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9V0</accession>
    <name>A0A8T0G9V0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G028300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298">
        <property type="entry name" value="PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12298:SF4">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="6">
        <location>
            <begin position="221"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="483" mass="53478" checksum="824827C5DE46AFE5" modified="2022-10-12" version="1">MSEMSEMAEMAEMAEMAEEMAEGDGNAGELSTAVLAMSLGHGLYGMSGIGKTVLAMNLRNRDLEDLEVESDGGDESDEELMVTLGFVQPVEESWKMARQQFPCKVGGTPAWLDPLKLPEGENTQCGICGNPLQFLVQVYAPIGVDDAAYREEVFHRSLFLFVCPDMACLQQDQHHQRKKREEKPCRSVKVFRSQLARTNRFYSYEPPSAESEPALKGVPVCTWCGTWKATSRCGGCKQVRYCSRTHQLAHWRAGHDSFCRTVQAELAAGNQQSDSTATETLQSSDAGQKMGTRVSETPQQPGIATAASDKLWPEMELIVGEEEDSSPSGDQGVSNDAQKLLEDYETRRAQNGEEFSAIDMQDVEESSLDQQHWAAFQARLARAPGQVLRYCRAVGAKPLWPSLQDQPKEGDVPRCQNCGGSRMFEFQLLPQLLYYLGVQNEADSDSLDWATIAVYTCAASCNKSDSSFEGYVEEFPWVQLAVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBH5</accession>
    <name>A0A8T0GBH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">T-complex protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G024000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TCP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008862">
        <property type="entry name" value="Tcp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832:SF11">
        <property type="entry name" value="LD23868P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12832">
        <property type="entry name" value="TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05794">
        <property type="entry name" value="Tcp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="392"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="492"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="634"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="494"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="654"/>
            <end position="685"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1263" mass="138703" checksum="6B2EFD907804C4B7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBK8</accession>
    <name>A0A8T0GBK8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G059700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBK8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48223:SF1">
        <property type="entry name" value="ABC TRANSMEMBRANE TYPE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48223">
        <property type="entry name" value="DEFECTIVE 2759, PUTATIVE ISOFORM 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035862020" evidence="2">
        <location>
            <begin position="21"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="348" mass="38216" checksum="C791AD9A5B0490BC" modified="2022-10-12" version="1">MALLNLRALGASSLQPVAVAAPLTRCQARASSSTISDVVTTKTRKICGTQHLSCGSSFLSSRSRDFVRLQRLHALSLQMVTADHDSSGEQEISAEPSTESAVEATDSSLGLQGNEHLKQMLVDSLQGFQEGLKDLRDRGVLESAKLGYQDAQEKVKNLDAKQLITDLKSSSLSAHGSRWWRTSDPWIKWPLAIFVPFFLLVTLIFGMSVSQDLLPLWILGPLSTGLIIRQCCRAAELSRVVAEKTASQRAQLSATTLALYKDAKDGTLPEKTKLLVGSKLAELEETVSTKRSEITVYVTSGQAAAGAKDFSMNKLNELGEHIVEAYADYMEWWRPKGRALSRFLKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEA0</accession>
    <name>A0A8T0GEA0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prostaglandin E synthase 2</fullName>
            <ecNumber evidence="3">5.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Microsomal prostaglandin E synthase 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_11G153200</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>prostaglandin H2 = (12S)-hydroxy-(5Z,8E,10E)-heptadecatrienoate + malonaldehyde</text>
            <dbReference type="Rhea" id="RHEA:48644"/>
            <dbReference type="ChEBI" id="CHEBI:57405"/>
            <dbReference type="ChEBI" id="CHEBI:90694"/>
            <dbReference type="ChEBI" id="CHEBI:566274"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="15">
            <dbReference type="Rhea" id="RHEA:48645"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>prostaglandin H2 = prostaglandin E2</text>
            <dbReference type="Rhea" id="RHEA:12893"/>
            <dbReference type="ChEBI" id="CHEBI:57405"/>
            <dbReference type="ChEBI" id="CHEBI:606564"/>
            <dbReference type="EC" id="5.3.99.3"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="16">
            <dbReference type="Rhea" id="RHEA:12894"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; prostaglandin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="18">Endomembrane system</location>
            <topology evidence="18">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.99.3" evidence="3"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEA0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050220">
        <property type="term" value="F:prostaglandin-E synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03197">
        <property type="entry name" value="GST_C_mPGES2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034334">
        <property type="entry name" value="PGES2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034335">
        <property type="entry name" value="PGES2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782">
        <property type="entry name" value="MICROSOMAL PROSTAGLANDIN E SYNTHASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12782:SF5">
        <property type="entry name" value="PROSTAGLANDIN E SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01182">
        <property type="entry name" value="Prostaglandin_E_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01203">
        <property type="entry name" value="Prostaglandin_E_synthase_like1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0643">Prostaglandin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0644">Prostaglandin metabolism</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="GST N-terminal" evidence="19">
        <location>
            <begin position="100"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00031041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0557736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="38497" checksum="6B1F3F1250B910AF" modified="2022-10-12" version="1">MQGGGGRAMAAARALRCVRARGSASVLQQSGRAFVTEVEDGVGLGFGARVKEQSARSSRQEARSRNGRWLAAGAFSLSFAASTMSVAFGKERVADRFAPKEVVLYQYDACPFCNKVKAFLDYHDIAYKVVEVNPMGKKEIKWSEYKKVPILVVDGEPLNDSTAIITELSRRIEAANASALTQEVESEEEEKWRSWVDEHLVHLLSPNIYRTPREALQAFDYLTTSGNFSTMERATGKYFGAAAMYVIGKRLKKRHNILDERAALYDAAEEWVKALDGRQFMGGSKPNLADLAVFGVLRPIRQLDTGRDMMASTKIGEWYARMEDAVGATARLQEEPLMGTIDNSMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GES6</accession>
    <name>A0A8T0GES6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G068800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GES6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035898158" evidence="1">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="47" mass="5515" checksum="73DC17A9EA4D4376" modified="2022-10-12" version="1">MFVCSCVCWRWLCRCISLLVGHEKVVVVHWSCGVSLVSKLSLIWREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF89</accession>
    <name>A0A8T0GF89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G121200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009627">
        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039265">
        <property type="entry name" value="DIR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122:SF75">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_PLANT LIPID TRANSFER PROTEIN_SEED STORAGE HELICAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122">
        <property type="entry name" value="LIPID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035915059" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="12329" checksum="AA8FB278420CDEEF" modified="2022-10-12" version="1">MAKSSMTMHPLLRLAVVMAVVTALMVHETQAADCPTNDLSSCMPAAYEDIQPTEECCTNLAAYTNTPTPAECLCQGALSSPLAGDDDVNVKYAVLIPQKCDLDYPAGTTCRGYVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI17</accession>
    <name>A0A8T0GI17_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_10G044600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Plastid</location>
            <location evidence="1 8">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000010">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="3 8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5 8" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0558663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="275" mass="29414" checksum="6A02235F38107273" modified="2022-10-12" version="1">MALLSSVASAATAVGAQAALRASRRHGELGLCAPGVVRVARGVKCRAQAEGITAAAPETVSTGVETVRPLWLPGSTPPAYLDGTLAGDFGFDPLGLGSDPRDLRWYVQAELVHARFAMAGVAGILFTDLLRASGRTDIPLWYEAGAYKFEFADTKTLFIVQLLLMGFVETKRWMDFVNPGSQAAEDSFFGLEPAFGGLENGYPGGPIFNPLGFAKDTGKSQPLRWKEIKNGRLAMVAMVGFIVQANVTKTGPIENLMAHLSDPLHTTIIQRIANH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIJ2</accession>
    <name>A0A8T0GIJ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G056800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="337"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="256"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="113"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="382" mass="42862" checksum="8707619844CF8CCC" modified="2022-10-12" version="1">MVTLEITVNKIISLNHRKAMTRMPKVCCQESYSVAELDGEADHDRGSLANESCQTALSMTEMQAVSNLAQIVHCERHAHTPQLRGGGSPHEHPHAHEHEHEHEHEHSCASERSAPNSVTWASSFPGASARNQLYANIPSVSKIPRPASPPKVPKVKWNSDVRCNWPPTSPPRTGPGSASTRRLTAASDSKTRDVGVMTFPAINAEELIKKVEALELELDVHVGNERQLLSVNEQLRKRLEVCLRELNDAGMMHIQLDNLNEEMEKILQLLRHLSERNAALEKEKAQVQAKLEREATLNKFQASRMLRGGSEDHDVDVRDAECQTICSCQQVDTRKRRRERKRWLEEETANGNKSRSKSLSPTQIRKSVVVVPQSLKPEVTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK86</accession>
    <name>A0A8T0GK86_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G070100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="410" mass="46645" checksum="802177503C95136B" modified="2022-10-12" version="1">MATNWDSLPHDMHDKILKKLEFKDLFRCKTVSKVWKKCIESDDFRQLRRETFSQEGSFTAISYNNYNNSWQCFGYDLHSKSWRSLPPFSYLPIPDVRGNMTIYSVTGHRSLMCAEVSELPNQCVLVVFNPLTGKKRILPPLLYPRNPMLVHISVNSAAKSYTIVVAGSSFASEKHLSKKVELFCSTTSKWTEASDLPSPMFGLSHHQAGVCVNGVLYVIAFLDGNGRQGMIAFDVENGKWLEEMACAIPFSLTSAILELVECDGKVHVYSMHMFKGLIRHCIHVLKTLDLNRRARASHWKAVVDVREHNFRGWQMYIGRRWQLYNEYSCVSFGDGKLCVFNVFSRNGMVYDMRDGRQISVLVAPPGTEKGEKFSTLNCASFSLQPCFDNDPMSSTVEIIENKDAKSVVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKF5</accession>
    <name>A0A8T0GKF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear pore protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G109200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NUP186/NUP192/NUP205 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11894">
        <property type="entry name" value="Nup192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0559493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33921" checksum="1231CE29A12DDC46" modified="2022-10-12" version="1">MAYYVLDALLAVDHHQVFLSQLQSRGLLHSCLAEISSNSYQAILLPSAESMRRLYTLESELALLLRVGYHNRKRGAQTLYAMGALRHLSSCRAIDAHLTDDAKWEQVKIGVGMPSQHDRQHQLVSPVLRLVLCFTALIDTTEATDGGRDEVALEVLEFIKSHQGLLDRILRDDTPGVHLADLDELQLATAILSKVWPVEESPEFGYTQAMFNLAYVYFCPDAESRSRFVQHIREAEKLSESSGAARETIRKMELQVARVRCNLIAYLYALVTKHSLRLHIFKPDIGDSATMVEISVLSIAMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKF6</accession>
    <name>A0A8T0GKF6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DM2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G145400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKF6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd10567">
        <property type="entry name" value="SWIB-MDM2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.245.10">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019835">
        <property type="entry name" value="SWIB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036885">
        <property type="entry name" value="SWIB_MDM2_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003121">
        <property type="entry name" value="SWIB_MDM2_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13844">
        <property type="entry name" value="SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02201">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00151">
        <property type="entry name" value="SWIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47592">
        <property type="entry name" value="SWIB/MDM2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51925">
        <property type="entry name" value="SWIB_MDM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DM2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14315" checksum="2C5209EEE0378959" modified="2022-10-12" version="1">MATKAASALGNGLNRTIQVSPALQRFLGVGECSRPESMKRVWDYIKDHKLQNPQNKKEVFCDETLKPVLGGKDKVGFLEIAKLLSEHFPKAPKVPKTPKAPKIPKEPKLPKEPKSPKSPRTRKVAAAPAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM41</accession>
    <name>A0A8T0GM41_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G153200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM41"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035725941" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7670" checksum="665FAEFA6FF170DC" modified="2022-10-12" version="1">MFMSAGFFSLLAVLGIMKYIAVDDYWYNIAAEDYEVVIKIFESIVLGGMDICSTAIWSDMDGNEGLCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMK3</accession>
    <name>A0A8T0GMK3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G012100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd11660">
        <property type="entry name" value="SANT_TRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47122">
        <property type="entry name" value="MYB-LIKE DNA-BINDING DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47122:SF8">
        <property type="entry name" value="MYB-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH myb-type" evidence="3">
        <location>
            <begin position="630"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="630"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="723"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="726"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="746" mass="81934" checksum="39F449977AEE0663" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMM2</accession>
    <name>A0A8T0GMM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase</fullName>
            <ecNumber evidence="5">2.7.8.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">GlcNAc-1-P transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="16">N-acetylglucosamine-1-phosphate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_9G013600</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-linked oligosaccharides begins on the cytosolic side of the endoplasmic reticulum membrane and finishes in its lumen. The sequential addition of sugars to dolichol pyrophosphate produces dolichol-linked oligosaccharides containing fourteen sugars, including two GlcNAcs, nine mannoses and three glucoses. Once assembled, the oligosaccharide is transferred from the lipid to nascent proteins by oligosaccharyltransferases. Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis, transfering GlcNAc-1-P from cytosolic UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol embedded in the cytoplasmic leaflet of the endoplasmic reticulum membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>a di-trans,poly-cis-dolichyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-alpha-D-glucosaminyl-diphospho-di-trans,poly-cis-dolichol + UMP</text>
            <dbReference type="Rhea" id="RHEA:13289"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19507"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58427"/>
            <dbReference type="EC" id="2.7.8.15"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="18">
            <dbReference type="Rhea" id="RHEA:13290"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.15" evidence="5"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMM2"/>
    <dbReference type="OrthoDB" id="10262326at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003975">
        <property type="term" value="F:UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06855">
        <property type="entry name" value="GT_GPT_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033895">
        <property type="entry name" value="GPT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10571:SF0">
        <property type="entry name" value="UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="118"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="19">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00029567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00033238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00044717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00045078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0560791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="429" mass="47660" checksum="EBCC6A701329F3DF" modified="2022-10-12" version="1">MADAKVRRRGNKPTPPHQQDPAAGIDDDDGKNAPVLTIKWSKLAMLAVLALSPYLLLLWFLPIDAGLMNSILTNLVMSVAGFAGVILLIPVASKYVLRRNMFGYDINKRGSAGGKVKVPESLGLVTGIVFLVVTILFQHFIFSPENNISDRYPPENAWLTEYYAALACICFMLFLGFVDDVLDLPWRVKLFLPSIAALPLLMAYAGRTIIVIPKPLRSPLGFTELNLGWVYKLYMGLLAVFCTNSVNILAGVNGLEVGQTVIISCAVLVHNVMQISRSDETRQAHAFSLYLMQPLVATSLGLLAFNWYPSSVFVGDTYTYFAGMALAVVGILGHFSETLLLFFLPQILNFLYSIPQLFKIVPCPRHRLPSFDPHTGLLTGSNDMNLVNLFLRWFGRCSEQQLCIRLLAFQVLACGFCFGLRYLMAGWYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP50</accession>
    <name>A0A8T0GP50_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="22">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_9G059300</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048544">
        <property type="term" value="P:recognition of pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000858">
        <property type="entry name" value="S_locus_glycoprot_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024171">
        <property type="entry name" value="SRK-like_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47974">
        <property type="entry name" value="OS07G0415500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47974:SF9">
        <property type="entry name" value="RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01453">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00954">
        <property type="entry name" value="S_locus_glycop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000641">
        <property type="entry name" value="SRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 17" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035784401" description="Non-specific serine/threonine protein kinase" evidence="17">
        <location>
            <begin position="35"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="489"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="19">
        <location>
            <begin position="45"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="552"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="581"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0561366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="22">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="938" mass="103713" checksum="41ACEEEC003F66C6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQI9</accession>
    <name>A0A8T0GQI9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G092400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQI9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="12"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="167" mass="17926" checksum="2C72E191B1A7B8A6" modified="2022-10-12" version="1" fragment="single">TEKEFDDRSLQSAAARAVAGPGAAPADDEGGSEGVGDAVPASTLRAHGHAVAISAIGVVGDFVRVDVDVAVTIAQRRRSCVHAFDSVVDHVLCRRGVVPSRRRCCWLLLLRVHRWIHGGSPWHFHGRTAGCRTALQSDSPIAHSRACPNLRTPRFEAPKPQLLICSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR59</accession>
    <name>A0A8T0GR59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="3">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">10-formyletrahydrofolate synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Formyltetrahydrofolate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_10G159900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:195366"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="3"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR59"/>
    <dbReference type="OrthoDB" id="5126881at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009257">
        <property type="term" value="P:10-formyltetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046655">
        <property type="term" value="P:folic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006555">
        <property type="term" value="P:methionine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000245">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001123">
        <property type="entry name" value="C-1-tetrahydrofolate synthase, cytoplasmic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.770:FF:000001">
        <property type="entry name" value="Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.410.10:FF:000001">
        <property type="entry name" value="Putative formate--tetrahydrofolate ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.410.10">
        <property type="entry name" value="Formyltetrahydrofolate synthetase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00070564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00079657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00083647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0560178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="633" mass="67380" checksum="B88CCF751F89032E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRB5</accession>
    <name>A0A8T0GRB5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_9G067000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRB5"/>
    <dbReference type="OrthoDB" id="10267969at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF17">
        <property type="entry name" value="PROTEIN MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0561473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="227" mass="25477" checksum="DE8C0EB6F53A58B0" modified="2022-10-12" version="1">MAGMMGSLRGVWGWYQVRLAQQPVRTQMITSGILWATGDYAAQSISRGLERRRAASSPHEKSTKVEESTDWKRVALASSFGVGFVGPVGHVWYEGLERFVIHGLKLRVNSVPFIATKVACDCLLFGPVHLLAFFSYMGLMSGRPWEKVKRDVERDFIPTYMTEGLGWAVVQVANFRLVPVRHQLLFVNVFCLVDSAFLSWVKYQDDAPWKKYLTSLVTPAKPSASAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSE3</accession>
    <name>A0A8T0GSE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G101900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSE3"/>
    <dbReference type="OrthoDB" id="6049624at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="12">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="13">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0561900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="451" mass="49748" checksum="B27A9F95290E426F" modified="2022-10-12" version="1">MRECLSIHVGQAGIQVGNACWELFCLEHGIQPDGQMPSDKTVGGGDDAFNTFFSETGAGKHVPRCVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLALDRVRKLADMCTGLQGFMVYHAVGGGTGSGLGSLLLERLSVDYGKKAKLSMCIFPSPQVSGAVVEPYNSVLSCHGLLEHTEVGVMYDNEAIYDICRRNLDIERPTYTNLNRLITQVMSSLTASLRFDGALNMDLTNFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVSELSNSVFEPSSMMAKCDPRHGKYIACAMMYRGDVVPKDVNASVGTIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMIANSTAVAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGADSTEGDGEDEGEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTF7</accession>
    <name>A0A8T0GTF7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G096300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000183">
        <property type="entry name" value="ABC transporter ATP-binding protein yjjK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008775">
        <property type="entry name" value="PRK11819.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858:SF1">
        <property type="entry name" value="ABC TRANSPORTER-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="ENERGY-DEPENDENT TRANSLATIONAL THROTTLE PROTEIN ETTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="9" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="110"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="13">
        <location>
            <begin position="430"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0561837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="658" mass="72094" checksum="564DB10F3DD49168" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVC0</accession>
    <name>A0A8T0GVC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G080500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RETICULATA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021825">
        <property type="entry name" value="RETICULATA-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31620">
        <property type="entry name" value="PROTEIN RETICULATA-RELATED 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31620:SF15">
        <property type="entry name" value="PROTEIN RETICULATA-RELATED 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11891">
        <property type="entry name" value="RETICULATA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="38324" checksum="254FBA306D856477" modified="2022-10-12" version="1">MASAMAGLIAQPSLQGIPQASLSSLNSSSISRQRVSCSLEFTSTSGFGKNPFISGKPYVSQLRASASSVPLGGDESSLGLGGGGNGAGLNGGGKSGGGGGGDSYGEGESEGGSPGGIFGTFWKGWNDRVRADPQFPFKVLMEEVVGVGACVLGDMACRPNFGLNELDFVFCTLVVGCIVNFMLMYMLAPTSAAGAVATHLPGIFASCPSGHMFEPGTYSLVQRAGTFVYKGAQFAVVGFAAGLVGTAISNTLIAVRTKLDPDFVVQNEAPPTILNAATWALHMGLSSNSRYQSLNGLEFALASKMPPAVFKTGVLVVRALNNVLGGSSFVALARITGSQKTATPPIPPVIADAEEKLLESVDEIMDETFGKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVL4</accession>
    <name>A0A8T0GVL4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G059300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="630" mass="66403" checksum="2476B9C6422F0998" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWY8</accession>
    <name>A0A8T0GWY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SP-RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G002500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein sumoylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NSE2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061665">
        <property type="term" value="F:SUMO ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016925">
        <property type="term" value="P:protein sumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16651">
        <property type="entry name" value="SPL-RING_NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026846">
        <property type="entry name" value="Nse2(Mms21)"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004181">
        <property type="entry name" value="Znf_MIZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21330:SF1">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE NSE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11789">
        <property type="entry name" value="zf-Nse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SP-RING-type" evidence="10">
        <location>
            <begin position="148"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF11789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0563067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="30426" checksum="8D01F66204E71E13" modified="2022-10-12" version="1">MATPSVDRVRSTIRALQWNTQDLLQDFDRTVLYAKLVAEDLEKYNDSDSVHELQDATLDILTASHNLRNHSKALDSISASYQPSSEVTNFEQLLRDRVREVEEESPFDPETHELLKEFKEAVWEVHHAGEPMPGQEEEEIVVTGASQAIPNTACALSGKPVDQLENPVRSRACRHIYERDAVIDYVRKHEAETQMTRRHRPHPCRCAAAGCPGILVEDQLICDRSLKIQIQEYMLRQQSSNVDVVADCTHIDEDDVTPLKASGSRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H083</accession>
    <name>A0A8T0H083_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G092900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H083"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="43" mass="4655" checksum="B87320FB38911FEA" modified="2022-10-12" version="1">MADYDRLCKMLSSQFVEDTKTGVLQLGLYGMAGLGKTTISKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0E2</accession>
    <name>A0A8T0H0E2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G090200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0E2"/>
    <dbReference type="OrthoDB" id="1641903at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037981">
        <property type="entry name" value="NCS2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11119">
        <property type="entry name" value="XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0564185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="57362" checksum="0D27E835396DE93A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H629</accession>
    <name>A0A8T0H629_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G002500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H629"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035870361" evidence="2">
        <location>
            <begin position="28"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7703" checksum="2662C08FA12E3E71" modified="2022-10-12" version="1">MCALGLFPRIFLTSFFLVLLMFYMCLCRSCCSVFDELMIDNEEILLSRILVFCSLHATLYSFARGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H667</accession>
    <name>A0A8T0H667_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G045900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H667"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056555">
        <property type="entry name" value="NFD4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010658">
        <property type="entry name" value="Nodulin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF22">
        <property type="entry name" value="F25A4.25 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23262">
        <property type="entry name" value="NFD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06813">
        <property type="entry name" value="Nodulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="564"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="Nodulin-like" evidence="7">
        <location>
            <begin position="11"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="NFD4 C-terminal" evidence="8">
        <location>
            <begin position="352"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="619" mass="67692" checksum="54B5F8B0794AFC22" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAD5</accession>
    <name>A0A8T0HAD5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TBCC domain-containing protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G005200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle pole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TBCC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAD5"/>
    <dbReference type="OrthoDB" id="427777at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017901">
        <property type="entry name" value="C-CAP_CF_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036223">
        <property type="entry name" value="CAP_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006599">
        <property type="entry name" value="CARP_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039589">
        <property type="entry name" value="TBCC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012945">
        <property type="entry name" value="Tubulin-bd_cofactor_C_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16052:SF0">
        <property type="entry name" value="TBCC DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07986">
        <property type="entry name" value="TBCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00673">
        <property type="entry name" value="CARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69340">
        <property type="entry name" value="C-terminal domain of adenylylcyclase associated protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51329">
        <property type="entry name" value="C_CAP_COFACTOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-CAP/cofactor C-like" evidence="7">
        <location>
            <begin position="336"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0568240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="627" mass="68225" checksum="CE5C37F9CA4F8887" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB50</accession>
    <name>A0A8T0HB50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G170200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12461" checksum="B1E6AD13B94D94C7" modified="2022-10-12" version="1">MEKSSGAPTKKSRYQGPHWCKKCYASVSTAMSKVAQVISSEEVLDDVGQAMYICERTFIECANFGGPKICPYFAQVDAVLKELFCFVSMIIISLQPTPWFLTSTDGLAWFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCQ2</accession>
    <name>A0A8T0HCQ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-isopropylmalate dehydratase</fullName>
            <ecNumber evidence="4">4.2.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G099000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of the large LEUC/IIL1 subunit and the small LEUD (SSU1, SSU2 or SSU3) subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LeuD family. LeuD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="4"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCQ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019761">
        <property type="term" value="P:glucosinolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000007">
        <property type="entry name" value="Isopropylmalate/citramalate isomerase small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050075">
        <property type="entry name" value="LeuD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43345:SF2">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43345">
        <property type="entry name" value="3-ISOPROPYLMALATE DEHYDRATASE SMALL SUBUNIT 2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="8">
        <location>
            <begin position="186"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00063576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0569551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="303" mass="32422" checksum="B080B1590B2B0636" modified="2022-10-12" version="1">MKHKRSWGVRTFAVAFRARGILFAECGARVAIVALPAMAAAALQVRLVPATAATTSSSSSSCSNRASSRSVSVPCIRRDGASVFGSVARFETRQEVRRVVSRGGVRALAGEVQAEGKDGRGCRVIHGRCFVVGDNIDTDQIIPAEYLTLVPSKPEEYEKLGSYAMIGLPEEWGKFIEEGKMKTEYKVIIGGDNFGCGSSREHAPVALGAAGCRAVVAETYARIFFRNSVATGELYPVETLGKIWEENHTGDIVTLDMEKDVLVNHTTGKTYNLKPIGEAGPVIDAGGIFSYARSTGMIASPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCR0</accession>
    <name>A0A8T0HCR0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G102200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="11328" checksum="D622C9A919CAE4E1" modified="2022-10-12" version="1">MNYIIRSRFYDMLQRFWSVLILHRNQEPTEGPNFIGHRLTERKDYVWGEKCTLQNSKYIEPTSRIKSSPVKKFVHILSTSTCTGQSKDRPAAFYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDM1</accession>
    <name>A0A8T0HDM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (quinone)</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G121500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + NADPH + H(+) = a quinol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF3">
        <property type="entry name" value="NAD(P)H DEHYDROGENASE (QUINONE) FQR1-LIKE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="109"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="50"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0569861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="310" mass="33010" checksum="18254614985C5C47" modified="2022-10-12" version="1">MGNILCCTTKSKNFNSTLSLEREIIVDAPVMDDAKIADALVSDEEIKQAQAPLDEEQTVDAPQDEEKVADASPGEENGEAKIVDASVDGGKSVDNNSLDVASVDAKVKVFIIFYSAYGHVLAMAKKMKEGVDSVEGVEGFLYQVPETLPENVLSMMKAPPKDESIPTITAAQLSEADGFLFGFPTRFGVMAAQMKAFFDSTGALWKTQALAGKPAGLFVSTGSQGGGQETTALTSITQLVHHGMLYVPIGYTFGSGMFTFDEIRGGSPYGAGTYAGNGSRKPSELELAMAKHQGQYTANFAKMMAKNKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEG0</accession>
    <name>A0A8T0HEG0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G084000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the complex I NDUFA5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEG0"/>
    <dbReference type="OrthoDB" id="286811at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006806">
        <property type="entry name" value="NDUFA5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12653">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04716">
        <property type="entry name" value="ETC_C1_NDUFA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0569345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="135" mass="15374" checksum="8C2E6E6765AC2065" modified="2022-10-12" version="1">MFLRRFAGPLLASVKESTGIVGLDVVPNAREALITLYQQTLKAVQPIPESAQYRKSVEALTNHRLQICQEEEDWANIEKRIKCGQVEELIVQAKDELQLIPKMAEWKPWEVPEGYKVEVIEDSDDSVPSHVPIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGQ8</accession>
    <name>A0A8T0HGQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G120400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18919">
        <property type="entry name" value="bHLH_AtBPE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000002">
        <property type="entry name" value="Basic helix-loop-helix transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024097">
        <property type="entry name" value="bHLH_ZIP_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12565:SF184">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12565">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="207"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="83"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0569847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="415" mass="45772" checksum="ED09DF2752034A50" modified="2022-10-12" version="1">MDFSSIDLALQNPSIANGLAMHEANPSVSHHCLTQLSFESGLAERMTNFTDGWPMNNTRPKFVHDSGNQRVCHEVQGFEIPAKGTTLGFGNERDEGGHIQQDNSSTSEQTAAPLQNRTGNTSGKRKACKDLTNTSTNSVKSSKGDENTAKCPRTDNASKGFDEAKSTAERSTSEHSGNLSPNSLKESSKLQSEPPKDYIHVRARRGQATDSHSLAERVRREKISERMKFLQALVPGCSKVTGKAVMLDEIINYVQSLQRQIEILSLKLAAVDPRLDSNMENLLNKELAAQAARSPETILLGPDPLASYRDYQLHMQIQPQINDCNMDLRSIGTLCDAYLGRTTNAQVLPPLAYTDNFVGSIPQTLGGVCDGDLQSVVHMGNSQGRQEFFNPGLHGKPHDLSYNKFFYFKVFTHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGS0</accession>
    <name>A0A8T0HGS0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Hydroxyisourate hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G170700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+) = (S)-allantoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:26301"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15678"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="4.1.1.97"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-hydroxyisourate + H2O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23736"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18072"/>
            <dbReference type="ChEBI" id="CHEBI:58639"/>
            <dbReference type="EC" id="3.5.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; urate degradation; (S)-allantoin from urate: step 3/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051997">
        <property type="term" value="F:2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033971">
        <property type="term" value="F:hydroxyisourate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019628">
        <property type="term" value="P:urate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05822">
        <property type="entry name" value="TLP_HIUase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3330.10">
        <property type="entry name" value="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.180">
        <property type="entry name" value="Transthyretin/hydroxyisourate hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014306">
        <property type="entry name" value="Hydroxyisourate_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018020">
        <property type="entry name" value="OHCU_decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036778">
        <property type="entry name" value="OHCU_decarboxylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023418">
        <property type="entry name" value="Thyroxine_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023416">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036817">
        <property type="entry name" value="Transthyretin/HIU_hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023419">
        <property type="entry name" value="Transthyretin_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02962">
        <property type="entry name" value="hdxy_isourate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43466">
        <property type="entry name" value="2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43466:SF1">
        <property type="entry name" value="2-OXO-4-HYDROXY-4-CARBOXY-5-UREIDOIMIDAZOLINE DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09349">
        <property type="entry name" value="OHCU_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00576">
        <property type="entry name" value="Transthyretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49472">
        <property type="entry name" value="Transthyretin (synonym: prealbumin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158694">
        <property type="entry name" value="UraD-Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00768">
        <property type="entry name" value="TRANSTHYRETIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00769">
        <property type="entry name" value="TRANSTHYRETIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0659">Purine metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase" evidence="10">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Transthyretin/hydroxyisourate hydrolase" evidence="9">
        <location>
            <begin position="204"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="168"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0570560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="36978" checksum="50DF18A5ABA235B3" modified="2022-10-12" version="1">MQSFLRCCGSVRFAQEMARVAPFSSLDLAVEAAREIWWNKVDISGWLEAFAAHPRIGDVETLRSKYANERICSEEQAAALNSANEHLLQELVEWNRQYEAKFGFVFLICAQDKSGSDILAALKERYCNRPIDELNNAASEQEKITELRLATLMSPDSNPDSHEASRGQLPSNLPMTSSTSNDNEEIFATPKPSSAPVSSLRPPITTHVLDVALGRPGSGIDVALHWWSDTSHAGTLESDTVDHGCWAPVGRSVTNKDGRSGPLMPASNHLQPGKYRLTFNTGDYMLRVHGGDKHEVFYPFVMVVFEVKPPQTSEHFHIPLLLAPYSYSTYRGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLY4</accession>
    <name>A0A8T0HLY4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG050900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLY4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="258" mass="30154" checksum="E30C9AFA9C1FC5A9" modified="2022-10-12" version="1">MLSNAAHPTVERMKVDQLTLATFNVQGLGRDMDGVRKRREFKEFFLRSNPKPDILMIHEDKFTLRDCNKRLKQMDFLRGSSYWNEAIYSAEKDSFRAGTGILLSPRLTPLVKSHGIIMSRRAQYLTFQLAPDMVIGIINIYAHNFTNSRIRLWNAIREFELPEAEWILTVDFNMIEDLEDKRGGTDSTGQGHLEFQAWTAMLLQLQLLDVHYLDEFRQLTNIRYTWNNRRHGLESIIFRLDRFYVSPRIQAIGGHSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM14</accession>
    <name>A0A8T0HM14_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG049000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="198" mass="22303" checksum="CA1C12C9B754C912" modified="2022-10-12" version="1">MFREGEDRHDVGLYGGWRTAIFMRYQIGATVGHLQVPIFIGHLGDKVLSRHLALGLSLGNDMHICDILHDQPIQLELQLLHSGRQIGVLFLYCTETLAGRHFSNHLGIVKWPDSASLKPFPDVSFSHGLTERQRDPLCQYLLCCGLTFVGHRPHISVHSKRCFEWLENGDIKRLKCVRGVGGQGDHVKPHFLGLSHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM33</accession>
    <name>A0A8T0HM33_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">K+ potassium transporter integral membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG050500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM33"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053951">
        <property type="entry name" value="K_trans_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540:SF83">
        <property type="entry name" value="K+ POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="OSMOTIC STRESS POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="190"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter integral membrane" evidence="4">
        <location>
            <begin position="66"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="230" mass="25251" checksum="6604FF99CDFF71F4" modified="2022-10-12" version="1">MEPVEGVANADMPQTFDGDPGEGQVTMVENHVDRSGNIDRSGVSDGRLWPVMQYTDKVSIAVLLTLAYQSFGVVYGDLSVSPLYVFRSTFGGALRNSVEEYEIEAVLCFIFWTLTLIPVIKYGFIVLGAHDNGEGGTFALYALLCRHLKLSLILNQQAADEELSSYKLDHPSTESPRGVWFRRLLEKHKFLQNGLLIVVLLGTCMVVGDGALTPALSGNQSQCLLFKIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNF8</accession>
    <name>A0A8T0HNF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Poly [ADP-ribose] polymerase</fullName>
            <shortName evidence="1">PARP</shortName>
            <ecNumber evidence="1">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG090600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="1"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003950">
        <property type="term" value="F:NAD+ poly-ADP-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012317">
        <property type="entry name" value="Poly(ADP-ribose)pol_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044964">
        <property type="entry name" value="RCD1/SRO1-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004170">
        <property type="entry name" value="WWE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037197">
        <property type="entry name" value="WWE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057823">
        <property type="entry name" value="WWE_RCD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32263">
        <property type="entry name" value="INACTIVE POLY [ADP-RIBOSE] POLYMERASE SRO4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32263:SF12">
        <property type="entry name" value="INACTIVE POLY [ADP-RIBOSE] POLYMERASE SRO4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00644">
        <property type="entry name" value="PARP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23467">
        <property type="entry name" value="WWE_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56399">
        <property type="entry name" value="ADP-ribosylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117839">
        <property type="entry name" value="WWE domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51059">
        <property type="entry name" value="PARP_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50918">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="WWE" evidence="2">
        <location>
            <begin position="85"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PARP catalytic" evidence="3">
        <location>
            <begin position="270"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0572382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="500" mass="54996" checksum="12DDD58F10ECBE7E" modified="2022-10-12" version="1">MDVYENRLRTGGGDVVHSFRVVGESPKRREREGERECKPMWRLSKRVTRDGGHYGSCVHGRIVEAVVRSRGGEQGGCRIDAEVESYGGDGSVPVGWSVVKSWRLMYFERGGWVEYGEEANCVAWKRFRGVQLTAEVVVEGRVSVLSFAEMTQVNLATGYVRSIAWSRDGWEISLPANPIIGPGEENLVGARVNRLRTSWRDGATDSVSSFMLGSDGVQGAQACESEWNDADHESVSILYDGSGDCELTKLTLGNCRSDAKSAVFGSKEKHANLGNYSGFSLTLGQRFAKLDEGEKEFDDVKSKFLSGFGKLAEGATITGIHRDSSPVAMARQVAFERQKVFTEQARGNTNVRYGWLGTSKKGMAGIFLHGFGQPKTLKNGSAYGVGVYLALENQPFVSAVYADIDENGEQHVVLCQVVPGVSELVKPPSEQFHPSSQHYDTGVDDVIAPKWPIVWSTHISTHILPLFVVSFKLPSRWHRMMAELNGKQRSSSKLCPDVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQJ9</accession>
    <name>A0A8T0HQJ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG158500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="199" mass="21853" checksum="8AEAA9EFDF28C4CE" modified="2022-10-12" version="1">MKVRFKISVLSSSSELPLTKRVNLLDQRRLEEITRIVGTGVCSVQEESPRSHLQRNSQPMRLDPHVLPLTLANDTDKHEVSSDVTFEGPTAEQGTDQNCGTLVGNEQEISSLRGSEAEATYSFVGEDLDDEHTLAVVFPSPKPAEQEDDEDIYSEDAVEGRFTSEAGQVDFTGVQASNTAVDTVVVVFSNDEGEDDDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQN5</accession>
    <name>A0A8T0HQN5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG131200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQN5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13612" checksum="B273B5FE5B11383B" modified="2022-10-12" version="1">MEIDLKRDCKFEGDLNPWSSDASSHGSCSLVEEGFEAAFGEVVPCAVGEMAFPARISNRPIVEGRFGDRNPQTHEPSQVNTHRADEPTASNQRRTLSFPWGTSGWVPFAFWFHPGYGALELAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRB7</accession>
    <name>A0A8T0HRB7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG185600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRB7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="19292" checksum="395B8589D7A9C1A2" modified="2022-10-12" version="1">MRLRNWRGRKTPRPKQKAIPREPIPWPLVSECPVGQLRDSPQPHHAHHRRPTKLRCEHLPITLHQRRHTFTSSSHHASKILTLRRPQHQNLKDPKKDRISYFSYLRVLARYFSPCTASLSFGRIFGTKKLTKSRQKVDKVKKYDRIDKNTKNNVEVIILDISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUV2</accession>
    <name>A0A8T0HUV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG253400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06467">
        <property type="entry name" value="p23_NUDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037898">
        <property type="entry name" value="NudC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356">
        <property type="entry name" value="NUCLEAR MOVEMENT PROTEIN NUDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12356:SF18">
        <property type="entry name" value="NUDC DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04969">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CS" evidence="1">
        <location>
            <begin position="17"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="177" mass="20461" checksum="01624FB6F46A1FB9" modified="2022-10-12" version="1">MAAEKLAPTERHRFEQDGDLIYEWDQQLEEVNMYIPLPDRLPTKLLYCTIKPKHLELGIKGNPPFLDHDLAGHVKTDCSFWTIGETSYPPLHRKPGPRNARDATETGERPTLAFSHSGTCFPRPTEVRAREAATDAGEVSRRASRLRLLQCRVHRKRTRSKQIFRWYSTLIGSRPWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWF3</accession>
    <name>A0A8T0HWF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G004200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16473" checksum="6E59F9766CC04163" modified="2022-10-12" version="1">MEAPERNVYPRDASFIWNGKNNRHCCNECRCLFCTALRWVVLPHCNCKLPYLSMGLPLDARIRRKRITCRHLPRHKTTPLGYCPCVVSGTNSWNALLDTKECDIRMGNLTGDIPHEDKFIGARMFDKRTKSGCTVEVETEWAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZK3</accession>
    <name>A0A8T0HZK3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G027800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08241">
        <property type="entry name" value="QOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF4">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="22"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="37060" checksum="AA1598406FD3D051" modified="2022-10-12" version="1">MATGTMRAVVCRKLGDPTLPMSDTSPIYIDEKHPKPKISTPTSVIVRVVASSVNFATGLQIQGKYQEKTALPYVPGEDFSGTVLAVGDRVTTVKPGDAVCGVAVGGAYAEELMVDASDLYKVPNGCDLLQAGGLPIAFGTSHIGLVHRANLQAGQVLLVLGAAGGVGSSAVQIGKLLGAVVIGVARGQEKAELLRTLGADLVVDPTDGGLINTVKAFLKSRKLRGVDVLYDPVGGKLFKDSMKLLSWGAKILVIGFTSGEIPSIPANILLVKNLTVHGLYWGSYKTFNPKVMQDSMQGLLEMLTNGSLRVHISHTFSLNEANKAFAMVSQREVRGKVIILPGGTSESPKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0S7</accession>
    <name>A0A8T0I0S7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G088100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0S7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="47637" checksum="C653AE04501F5DF4" modified="2022-10-12" version="1">MERKVTDNASVREMLKSREGGAGRAIMGLEAQSKRADDGLVMDPAMWGTLPKELIRLVCAHLPLPELLTLRRAALEDNWDINLDDSGFRRLCGRIHVNLCAVMVPGTGSSNLVYNVGLHSSVVSTAWQKLKLGVGQSSNIMSSSDGGLVCFALPIRSPSPGDTLVIRVVNPLTEDCRELPEVHGMRPHHPTMMKLVVDRNTKCYQVILLARRLEFFGEVRAMVFDSGKQMWTNSKGCSGIFFGLEYSSFRGAWGERPWSFDCATGQLVYLHKFDGNPCAGKFSSNCAHVKDHLFVIEMGLEDDEMSFGDGDDGFPTQFSVSEHKIQVQNVGLSCTKVTDHHFGEIDHPGMNLHAYELATNSYRCQYLRLLACEGFLLALGKSKTEFAWLYDLSTGEGLDLLKQRDGHQIATQVMPRVMFCELQWDVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I131</accession>
    <name>A0A8T0I131_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G072900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I131"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010903">
        <property type="entry name" value="DUF1517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053023">
        <property type="entry name" value="FLAP_modulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975:SF2">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07466">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="44799" checksum="C9CCFD60D7A66874" modified="2022-10-12" version="1">MAQLGAMMATGCMHGSMVRPAGLGERHSSIFGTGVAFPRRRIAVGSSERREFSRCVKAVSGDGDEKEGVEKGGSWLERVGESMKRVSKPTMAVMLSLMLLESSPDMAALAASGGRVGGRVGGGSSFSSKSFSAPSRSYSAPSRPYSGPSMGGYGAPRQYIAPSPRFSYAVPYAAPSPFFGGGVYAAPAYGLGLGAGGVFFLLIVGFIVLQAFYGFLSERSGLRGSSVLSGTQPVSVLKLQVGLLGMGRSLQKDLDRIAGQADTTTVEGLHYILTETCLALMRHPDYCISGVTSNDINRSISVAEERFNSLSLEERGKFDEETLVNVNNLRKRMQMDARRAERFNNEYIVVTVLVAAEGEYKLPTINGNSDLKDALRKLGSIPADSIQAVEVLWTPQDENDTLSERELLRDYPLLRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1T7</accession>
    <name>A0A8T0I1T7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G154600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1T7"/>
    <dbReference type="OrthoDB" id="153872at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="316"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="418"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="441" mass="51714" checksum="453FC440800457C8" modified="2022-10-12" version="1">MDAFRKQLDALMGANRNGDVLEVKRNYWDRDVCRLYLTGLCPHDLFQLTKMDLGPCSKVHSLQLRKEYEEAKANGKDNYDRDLEDCLEKHIIECDRKIQRALKRLEDDDAGAATAIAVSEVTKSPEALEYTRQIKEKLKAAEYLDLEGRSDDKIRIMEVVHELQTKRADKQAMSLLEAFNKDRSLMPQPLGNPPPLAPLPTLVTLPPDARTQEMIKEKLKKAEELGELGMVDEAQKAMEEAEALKKLGARQEAVTDPAKLLAPEVRIADQKLRVCDICGAFLSIYDSDRRLADHFGGKLHLGYMQIREKLVDLRAERSSRKVELPNDEKPREPSKARSMSRDREKERDADRERTDREKEKEAERERERDRERERSRGREKERGRDYRGGSGRDRERERDRGRSDRDYDSRSRRRSRSRSRERSRDRDRSDRYRRHDRYDRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4R5</accession>
    <name>A0A8T0I4R5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G190200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="49968" checksum="4F98A3A857C0503E" modified="2022-10-12" version="1">MASRFSDSSLYCVAELVRWHLPARSLVRFKLVNKEWETWISQNLRELAKVRKQTPSDWYFPITAMSYGEGRAGAEAKPLAAIHHPSDEEHKLPDLDYLPNWRGGRSNPYSIKAVSGGLFLSYYNSSGLSTSDFYVVNPLTRKWRKLSRGNCCHELGWDFLHAQMVVDENEGAYTVIVLTDNCVNVYSSHFKHWVCNPVRYSTGIHDPFLHDPFLPLCARSRFPASACVDGYVYVCSRILKERPRSVVEIQMFPMQPVAGQHPTRSPTIVALGNFRAFDIYLGRVYLNLASPKLVECMGGIYIVVCNCEIVETSQNTVPGVLAVGVLAVVMRRVIHIFKFQEGSKICPLHVHYVSERKLLIGSRIFSVVWNRRDKFSCTAKSSVIWVAWDNHLLQYDVVSSVWKDGYHSTDLFSSEDHKLLNQDYDLLPSAYTPSFDLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5I8</accession>
    <name>A0A8T0I5I8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G011300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5I8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="15463" checksum="9123C1C94DB57A31" modified="2022-10-12" version="1">MLVLEVDFEYGSNLGESFKFWLCWKRERENAGSRTSVNREFCWVWWDLCLPSCARAQAHGQKKPGVLSFEALLSALEKENLNEKAEQVHSETDYRPCSFCSQGPVTVLQMLVGEGMLGFTWATICACHGRRSCFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I643</accession>
    <name>A0A8T0I643_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G061300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I643"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="2">
        <location>
            <begin position="7"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="179" mass="21644" checksum="DB8B1DC0B5A8F53E" modified="2022-10-12" version="1">MIMPKCDLIREALTHVKKQHQGVSLIQIRKHLEATYQEKMDSKKKKFIVNTFKTLIQEGKLLQKGSIYKSTKKKETIRDVPRRKYCPRRYYRKSYNRRRLQRRRQRIRRRCDRRGHHVRKYHKVCIQKAHRQIKGRRGEGLVENPDYTNSVPSVEVSNEKLVKEKSTSRRSKTSQRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7W2</accession>
    <name>A0A8T0I7W2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G048400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7W2"/>
    <dbReference type="OrthoDB" id="1887912at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33915:SF1">
        <property type="entry name" value="OS04G0644100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33915">
        <property type="entry name" value="OSJNBA0033G05.11 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="SAM" evidence="2">
        <location>
            <begin position="56"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="335" mass="38274" checksum="E7048B637F21F7E8" modified="2022-10-12" version="1">MQVFQISNTRQRCILVVVLLVLKLVVIWMVIFHRCSKAPLIEESGYSDTMTIEWFSWLAEVGMQKHGRLMVSNHLDEDDIEHFNHDLLRSIGVDNAKDRLLILNQKNKHIQRRSSNKNHLSSRQLAAEAQSAIIRRVQTLQVDEVKLVNWIRKTWPLCNRQILIDRGYLSATAPKPGSVAVMANYDRTHIGNELLNSAKDILWAALYGTFESNVLIHRVERELLVITIPGRKAFVFNFFQAVTEVGALGTWRDPANRCHDEDESNMLLQVEYGESANEVVGDAIMVSIHVINLLEVNEVVLYARSSNIEQSTLLTELYFEKHQLAAAMLHKPGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7X7</accession>
    <name>A0A8T0I7X7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">LIMR family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G079800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7X7"/>
    <dbReference type="OrthoDB" id="73273at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006876">
        <property type="entry name" value="LMBR1-like_membr_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31652:SF0">
        <property type="entry name" value="LIMR FAMILY PROTEIN DDB_G0283707-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04791">
        <property type="entry name" value="LMBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="482"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="263"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="57709" checksum="B51889E942DBA872" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7Z1</accession>
    <name>A0A8T0I7Z1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G031600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7Z1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="255" mass="29663" checksum="9B0F2465FE0551C9" modified="2022-10-12" version="1">MDHAENIRYQLDSFTLDPMSATSIALIIVQLIRKVSRLLQKNTMAQRRCKKECEELKELLTSIRPDVITTESAVRLCKEGGIEMTPEDSWLRRLEKELEETSGLLDKFSDNSGVLKYITGDGLPKKITTQMETLTKFANELPLLHVGLQNLLIHRAASQPYNFSSTRRLPSFKNHRYHDTEYSSVFDSFRPSSSIIRLPSFERHCYPDAEFFMRDGVYFTRIPVSHPHFCTQVSFSRLPVTNPHYFKQVESEYYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8V3</accession>
    <name>A0A8T0I8V3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SS18 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G095000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007726">
        <property type="entry name" value="SS18_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05030">
        <property type="entry name" value="SSXT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SS18 N-terminal" evidence="3">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="150"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="22978" checksum="E168B6666A70ABDA" modified="2022-10-12" version="1">MPNNNMPPHMPPYATTNVTTEVIQRYLDENKLLILAILDNQQTKPADRARYQAKLQQNLMYLGAIADAYPQPGHHVGQSSQAVYAPQPLATMPPSPSFIHQQQQMMMMNQGIAMRPSYLQQSQAQASQQQFYNRHSSMLMNNLNLGLGVHDRVLMPPPGHPDHGGQGGHGDGNPMPPNVQGDLQLGGSGREDATASYLKNSDGSGVSGAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I924</accession>
    <name>A0A8T0I924_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 4C</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G160000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I924"/>
    <dbReference type="OrthoDB" id="274995at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000131">
        <property type="entry name" value="Eukaryotic translation initiation factor 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018104">
        <property type="entry name" value="TIF_eIF-1A_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00523">
        <property type="entry name" value="eIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="EIF-1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01262">
        <property type="entry name" value="IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="9">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="119"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0580250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16443" checksum="117E5428FD45AFFA" modified="2022-10-12" version="1">MPKNKGKGGKNRKRGKNEAEDEKRELVFKEDGQEYAQVLRMLGNGRCEALCIDGTKRLCHIRGKMHKKVWIASGDIILVGLRDYQDDKADVILKYQPDEARLLKAYGELPENVRLNEGIAGGMDDEEEGGGDDYVEFEDEDIDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I939</accession>
    <name>A0A8T0I939_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G161900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I939"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050424">
        <property type="entry name" value="Gfo-Idh-MocA_inositol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43593:SF1">
        <property type="entry name" value="INOSITOL 2-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase C-terminal" evidence="2">
        <location>
            <begin position="153"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="40816" checksum="195D4A7AD582AAD6" modified="2022-10-12" version="1">MGSEGRVLKYGIIGVGMMGREHLYNLAALPGAMVVAVADPHPGSREAALAATAGLQSVTAPPPLKVFEDHGALLDSGMCDIVVIATPNMTHAQILLDVLAHPKAHHVLVEKPLCTTIEDCYKVLEAAKARPDVLVQVGLEYRYIPAVAELLTQVRQNAVGRVRMVAIREHRFPFLVKVDNWNRFNKNTGGTLVEKCCHFFDLMTLIANSNPVRVMASGAQNVNHLDERYNGKVPDILDNAYVTVEYENGSRGILDLCMFAEGSRNEQEICAVGDSGKVEAFVPDSIVRVGSRTSGRDGVQSFEVHDKRVRYEGLHHGSSYLEHMEFALAVHSHGKQPPAVGLEAGLMSVAVGVAAHKSIESGRFVTLEEILDRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB81</accession>
    <name>A0A8T0IB81_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G120800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the calycin superfamily. Lipocalin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022271">
        <property type="entry name" value="Lipocalin_ApoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036893">
        <property type="entry name" value="Lipocalin_ApoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035981229" description="Lipocalin/cytosolic fatty-acid binding domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="3">
        <location>
            <begin position="44"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR036893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="22620" checksum="6798F8574C119B2C" modified="2022-10-12" version="1">MARIEAHVTWLCVVVAMVVCLGGGVEAGRGLLQASCPSPVLPDVNLPAYLGVWYEIGSTALIKTRTESGLACITARYSLIQSGPNAQSIRVRNEGYNTTSGEYSTIIGIASVTGRSLRVSFPPGPDADYRIIYLKGDAEDRYDTAVVYSCDAGQSGGFQSLYILSRKPTLDSDESVAGIIEYARTQGITLEATNQFVYTDQDGITCGRNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID28</accession>
    <name>A0A8T0ID28_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytidyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G167900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000309">
        <property type="term" value="F:nicotinamide-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000180">
        <property type="entry name" value="Cytidyltransferase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31285:SF0">
        <property type="entry name" value="NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytidyltransferase-like" evidence="1">
        <location>
            <begin position="220"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="41997" checksum="2DE6ED3403DAB88C" modified="2022-10-12" version="1">MSKMDSVLRAVIEAIHSSPTQFVLCLSGGASQVLGWLLSVPGASRTVLEATIPYSRASMVQLLGKVPTQSVCRETADEIATAAYNRALKLSMPGTQVAGIGFTGALASVPPKRGDHRCHVSARTQTGLWRYDLVLAKGYRDRYGEDYLTSCVTIKTLADVCGVSEDVPLVLQEGTEELRQAKVVYSEEEQFEQLLSGQICMIKFSGDSNSTSGGTRRVILSGSFNPLHDGHIKLLDAACRLREGGLPCYEISAINADKPPLGLADIKARSKQFHSAGKPLVVTNQPYFYKKAELFPDSTFVVGVDTALRLVDPKYYGNSTDRMLEVMEGIKQLGCDFFVAGRTVGGTFQVLSDVQIPDKIQSMFQKIPEFRVDLSSTQLRQAAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID39</accession>
    <name>A0A8T0ID39_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small integral membrane protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G172000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID39"/>
    <dbReference type="OrthoDB" id="1880105at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026686">
        <property type="entry name" value="UPF0708"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14937">
        <property type="entry name" value="DUF4500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8382" checksum="F52F4988686D0305" modified="2022-10-12" version="1">MSGDKYDWLKRTTTFSRIVNPELHAKPNLTVGAIGTGVFVFVLGNLLYQRHVLLQKQTEAQTPKLELLIKENEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDS5</accession>
    <name>A0A8T0IDS5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G016700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family. CGFS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03028">
        <property type="entry name" value="GRX_PICOT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000005">
        <property type="entry name" value="Glutaredoxin 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033658">
        <property type="entry name" value="GRX_PICOT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004480">
        <property type="entry name" value="Monothiol_GRX-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00365">
        <property type="entry name" value="Grx4 family monothiol glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293">
        <property type="entry name" value="GLUTAREDOXIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10293:SF72">
        <property type="entry name" value="MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="7">
        <location>
            <begin position="91"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19520" checksum="A7B7E0982B9D4ACF" modified="2022-10-12" version="1">MATTMRSLQSSSLVGHATAVAEVSATQPASLRCVWKGVGFKAGGSSALIARRELRVKHVAPRSSMGPSGGGGALTPELKEALDKYLNENKVVLFMKGNKMFPQCGFSNTCVQILNSLEVPYETVNILEDDSLRQGMKEYSAWPTFPQLYIDGEFFGGCDITLESYSSGELKEVLERAMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEW3</accession>
    <name>A0A8T0IEW3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G248200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11268" checksum="321EB3280EE76CF1" modified="2022-10-12" version="1">MEMIAHSYISDSAPETMFDDVDGFPKDVPKKGRTSKGGRKSTRGRGFGGISKASTGGRHGGIGSRHGGIGRGHGRLGGGRHGGGRQKPRAKRQKITKGRGKRTTSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFR7</accession>
    <name>A0A8T0IFR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G070100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010158">
        <property type="term" value="P:abaxial cell fate specification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000002">
        <property type="entry name" value="Myb family transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044847">
        <property type="entry name" value="KAN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31496">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAN2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31496:SF3">
        <property type="entry name" value="TRANSCRIPTION REPRESSOR KAN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="3" id="KW-0221">Differentiation</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="306"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="358"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="453" mass="50670" checksum="6CAB4BD04056A856" modified="2022-10-12" version="1">MIMQECSPDKPMSVLSSTNNPPSGPDLALHISPPNSSSEDIRSKPSVPQHYASNQELPEHVHGFDLWKQPPKSLSSITDSESNVSSPVSQQRPTYDNVGASTVLCLANPPSDHPPQMAAREEVHDNRYMHNTALPHQFLVDRSSSPSERVLKDFPRMYSMYTNEIQDDFARRLGETTIDHLHSQQRVFPQAPHMSPIIPELSLGRLSEHPEALPLPRPDLPKLQNYHMVGRDPGLRYSGYYGFEDDVSRQVGKAMSGMQTSTLSGNLSSLLGDAYNAKHDGIYGNLAFRSRFPLKSPSRKSIRAPRMRWTTTLHAHFVQAVELLGGHERATPKSVLELMNVKDLTLAHVKSHLQMYRTVKTSDKSGPSPGPGDRSPDARTPIDTLPMTDKGRNTMHMSNAGVHNLELSDYHRMGDRQETTVAMQNRTWLQERQGPNYNPTERGGCWKFGTLSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH63</accession>
    <name>A0A8T0IH63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G044300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8358" checksum="C7DB86F6A7C907DD" modified="2022-10-12" version="1">MVPRDPSVARRCGLHARCQTVYAQQFSFNTSRLWQLREAVRLIRLQCAIRLRPFCDQDEGEVYCRGLSSAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II82</accession>
    <name>A0A8T0II82_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G142900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="20111" checksum="82CEEFF86E135260" modified="2022-10-12" version="1">MDRVHKEYLQHNDISPGNVLLHFPEDKVSEVYIGVCDWGLASRVYETTPSRYGYPTAEARTAAFKERGTFVAPELWYTYGKPNSETSYETLRRRHLYTQAADAYLVGVVANMIWKDEDDFDLFKDVAGKARFAVALKELTNPDPKNRSTLQLVHATLTAPPYNFQIPECCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ61</accession>
    <name>A0A8T0IJ61_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G096500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="218"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="269" mass="29447" checksum="F8B981CB647CD771" modified="2022-10-12" version="1">MLGALRDVAHGAQCMNQLKNLLIPHPRCDMPQLEIVVCRASGRCLAVETYKCEALALAETSRSQCQHSATASTISLAAAINTFYATPRLPSFSNHNLKNNHSSSREDSSDTAKNSLLGDDFRRCPNTHEFAVQANNCSALYLQSMSTTQINVLSNHHHHHHHHHHHHLRSITPSQHHRQRITITNSSSNLDLHSAPSITQTKSSHALLPAQITPSHFSQTSNKSPSSTSTHAPKPPPSPPPKLTPNGQPNSHAHEITHHKPSSTTSMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILC0</accession>
    <name>A0A8T0ILC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G180900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="41"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="303" mass="35265" checksum="C4C22ADDE5CE2D17" modified="2022-10-12" version="1">MKRRWEADDAAPDNPESSRRRDVNAEGRSNEGIGDDPILYSCHKIFLSHSGAQKDFVEQLCQDLEKRYHFPFFDKRPSSLPKGERFPELILKAARQCQMAVIVISEEYFMSKWPMIELHAFVQARLGSNSKLKILPLFYKLLVDEFRNEERRKQWFGVWKDWAKVDPRINVDEWKDSLKILASFNGIEHDGDLRAIEAYRENIVLNICNEVSSEIQWDDSHVRGRSNLCQELCYKFNQIWSSNESKVCLIGIYGVGGIGKTTLCKTLCNELSQKFNGRVRHIEFGHGSSEELLKEVLRELLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILC9</accession>
    <name>A0A8T0ILC9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G152600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="16"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="836" mass="92434" checksum="F07D9EB92D22A9F9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM35</accession>
    <name>A0A8T0IM35_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G143700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035883658" evidence="1">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="7604" checksum="72FF45F73B23953C" modified="2022-10-12" version="1">MRFIKHIKHIVSLCMVSVCMGHNTKCVVIETATDSTYASVQFAVDLLNVCPSVLSDVGVPGRLDSGSLIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM66</accession>
    <name>A0A8T0IM66_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G186200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14954" checksum="D0241B5A14C5AC85" modified="2022-10-12" version="1">MLGGTFIDTRKVTIYGLKFATACVKRLSKAMRFTGMRLLRRLTSRCLFLLHALQKLPLNLHHLILHLPKLPPPPGPIDTQTSEGHHVRGPHVRIRPRVLRRPLPLLLTPLQKPPRLHITPNLHALFPRHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INR2</accession>
    <name>A0A8T0INR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G224000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INR2"/>
    <dbReference type="OrthoDB" id="1433814at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37186">
        <property type="entry name" value="OS06G0524500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37186:SF1">
        <property type="entry name" value="OS06G0524500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="16787" checksum="DA52F5F376E89178" modified="2022-10-12" version="1">MAMAMETESFAVRSGLRSVRSALLPGFATLQRHSFPNSTSLEPVFASCYGCGTGMVGGVGGMRSFASSTNPPEVKGFKDYKLPPVNPPEKENPDAVTLRAQWDNAVRLYGRMYSHAWGTAIMAGVALFGIGWWVKGENPLNALSPTGEIKKEETAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQG2</accession>
    <name>A0A8T0IQG2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G000100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="16320" checksum="07D6B77A51121CC0" modified="2022-10-12" version="1">MDSQELDTMPVMSSQPTNSRRRSRDEEPPVPRRRRRIPSNRSLVIVFEVEPAFNGLPEGVFAGQFHNEDTEVHAWSEVEGVGHYRWLQGPMNHLPREQELEFIADVMRQIFIFLRWYRPAAKLLLGDLEARRGGDVTDIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS76</accession>
    <name>A0A8T0IS76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G018200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="17832" checksum="4465CAA4A265DB5D" modified="2022-10-12" version="1">MERSGRTGTLLAVKRGLYDTLVAENSRRNAGTMKTSMRGSKSPTKADHSMKHSTMPMSPDQMGRGSTMPLSYLNYRDTGTERYSHSGRGNSVNFLQKNRQACSRTGNSAAGLSPLRSKIGQAPMIGDALGTPSNRGSSSFMSAGHNGVRDPEFKVGFKKREHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISM4</accession>
    <name>A0A8T0ISM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="11">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G038000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = N(6)-[(R)-lipoyl]-L-lysyl-[protein] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="9 11">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="11"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISM4"/>
    <dbReference type="OrthoDB" id="361797at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006103">
        <property type="term" value="P:2-oxoglutarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.30:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000001">
        <property type="entry name" value="Dihydrolipoyl dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050151">
        <property type="entry name" value="Class-I_Pyr_Nuc-Dis_Oxidored"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912:SF223">
        <property type="entry name" value="DIHYDROLIPOYL DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22912">
        <property type="entry name" value="DISULFIDE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="2 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5 9 11" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="13">
        <location>
            <begin position="41"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="12">
        <location>
            <begin position="385"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="483"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="217"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="351"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="357"/>
            <end position="360"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="10">
        <location>
            <begin position="78"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0585776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="504" mass="53067" checksum="2DAA94599445F347" modified="2022-10-12" version="1">MAARSSTRKAVQQVTQRLYLYRVGGAQRGYAAAAAAEADQDVVVVGGGPGGYVAAIKAAQLGFKTTCIESRGSLGGTCLNVGCIPSKALLQSSHMYHDAQHNFKSHGVNVGSVSIDLPAMMQQKDKAVTGLTKGIEGLFKKNKVTYVKGYGKITSPNEVTVELLDGGSQTVKGKNIIIATGSAVKGLPGITIDEQKVVSSTGALALKEVPEKLVVIGGGYIGLEMGSVWGRLGSQVTVVEFGDAIVPSMDAEVRKSFQRSLEKQKMKFKLKTKVVKVEENANGGLTLHLEAAEGGSPSTLEANVVLVAAGRTPFTKGLGLEELGVKVDKFGRVEVDHSFKTSVPGVFAIGDVIPGPMLAHKAEEDGVACVELIAGKAGHVNYDTVPGVVYTHPEVASVGKTEEQVKAANIQYRVGKFPFMANSRARSIDDAEGMVKIIADKETDKILGVHIMGPSAGELIHEAVLAMEYGASSEDIARVCHGHPTLSEAVKEAAMATYDKPIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU97</accession>
    <name>A0A8T0IU97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G111700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035913846" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5990" checksum="BA23AB06C4B363D2" modified="2022-10-12" version="1">MLSKDHFLVKLFLVVSKACACGEKFRQFKMSLLNWSLEAGLESGLEFYSSNSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV51</accession>
    <name>A0A8T0IV51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G100000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant 'ANKYRIN-BTB/POZ' family. 'NOOT-BOP-COCH-like' (NBCL) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18310">
        <property type="entry name" value="BTB_POZ_NPR_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044284">
        <property type="entry name" value="NPR5/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46668">
        <property type="entry name" value="BTB/POZ DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN NH5.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46668:SF1">
        <property type="entry name" value="REGULATORY PROTEIN NPR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="27"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00044752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="555" mass="61181" checksum="47DE2360A247FD81" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVY9</accession>
    <name>A0A8T0IVY9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G198800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVY9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="160"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0587884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="695" mass="78544" checksum="E64C364E51DB418F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWF2</accession>
    <name>A0A8T0IWF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G212200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWF2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="160"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="55451" checksum="C0DB3A0565AF15B9" modified="2022-10-12" version="1">MECATTCCGKCNMAAPSCEESLRELMRVMRRGVKLVSDCLREDWWESVLIRSECSSFSTHIVLHLDDFISCVNTVKLSFAEATGDLEFSVPLKPDRTHLSALIEDATQENNAYLLGVVKRIVEVGGVTADKKLAIFFMQARSINSELSEVQSIGPCDVVFPPGENIRVGASGRVKIATWSDKTSVAVKFMADAEQVRSEVMLLEFLAHPNVVKLIGIGLPKDSDKGQYLVLELMRTSLRNLINTRSDGGRKPPFEIYTAIDIMLQIAEALRHVHEHGVLHCDVKADNVLINDDDLTALGNVQIKVTDFGLARKIESSKPLVSLEYAGTPGWMAPELFEIRRTQGVPYYTAASDVYAFAVTCFEILSGQVPFEDVHDSDTLRAKLVAGDRPSLPDIYPQYLRQCIRMCWATNPEDRPSFGHICEMLKFFRGFCIRYRPGSATALASVNEHDAWELSHFSIMMLRSVDDVACSYAASLYVVACGEKVCLSQRPIRFKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWI1</accession>
    <name>A0A8T0IWI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G147500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035820951" evidence="2">
        <location>
            <begin position="24"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="152"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="20564" checksum="54DC9B0A4B106F34" modified="2022-10-12" version="1">MRKQHCLGMVLLQLASVAILVFSVENDGSLSFGETRVPYKDSSPLKHEAEGLHLLPSVSLEHNHQELNDPGVSDHPSTSRRLLAQLGRRLDGRGGGGRGPGRGGGGFGGGHGGGGSGRGHGGGEFGGGHGRGGGDRGGDRGRWEGGGDDEGGGGGGGGGGGGDGICIGYCPGGGNGGGGGGGGGGSTPSATTQSTTTPSLTPSTSTSDSAATKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX60</accession>
    <name>A0A8T0IX60_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G190400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032299">
        <property type="term" value="C:ribonuclease H2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09271">
        <property type="entry name" value="RNase_H2-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013924">
        <property type="entry name" value="RNase_H2_suC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204">
        <property type="entry name" value="OS02G0168900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47204:SF1">
        <property type="entry name" value="RIBONUCLEASE H2 SUBUNIT C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08615">
        <property type="entry name" value="RNase_H2_suC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="196" mass="21582" checksum="152782269738C471" modified="2022-10-12" version="1">MGSVEGEKERAEKQGCIGVMNVGAGLEDKTMHMLPCGTNYTGPAAVDDYFKIRAAGTNEDGIVMKEAAFRGRKLMGSTLLLPDGFCGFVLKKDAGLNPENGKAKVKSSDKEAFDVWAADSRFGGFTYWNHDTLPSKADHIRSVMEWLPVSAALHEEVTTDEVAAMAEKVKTQSGLHITIKREYSRFFNFLWICAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0F6</accession>
    <name>A0A8T0J0F6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RWP-RK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G217600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0F6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003035">
        <property type="entry name" value="RWP-RK_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48316">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48316:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02042">
        <property type="entry name" value="RWP-RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51519">
        <property type="entry name" value="RWP_RK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RWP-RK" evidence="6">
        <location>
            <begin position="7"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="94"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="155"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="343" mass="36813" checksum="C7FD8AA8D2546718" modified="2022-10-12" version="1">MPSDVLTNRHMAKLGMAPQPVSWSDGPLTIQDVSKFFSVPIAEAAQKLSVCGSVLQRICKENGIARWPYRKVTSGKSAEEIIEEGIKELASNPSAYKVAEKQPPTTPENTSNISGTPVASIPISSPPTEPDSVMNVGQPDPKRPARQQEVALVQPSPSQKSTQRNASGAQAKTLAQGSTPPQRVNQQGTPSHLNSPASSHVRSTAALHPLTPQKQKPASILDDFKIGFPTKGLRRASTRWWGSLEKESAILPEPAGDRDAELMCPESSVKGLESVSEVSPPTASSLLVRTRRKASLRGRSAVAHAVTRGYGLHQLGAKDAATLKFVFGDYLPKHWTSSFPPMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J111</accession>
    <name>A0A8T0J111_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G260200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J111"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751303" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9157" checksum="9D2149C2CA4E60B3" modified="2022-10-12" version="1">MLYFFMHFIIPQAIHGMFCVQLVYVQTKAKSEEEFQCGPTCACLIFLSLMNHTFAVLSYSFLNCFKGSIPSPYPCQLICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1J8</accession>
    <name>A0A8T0J1J8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G049200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1J8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035845793" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7668" checksum="0720A1B09A6062FC" modified="2022-10-12" version="1">MNVWRGVLMLLFKTQVLEFAPWLAFRMCSFHDHDQRFMTLLVVVSLLQCRDHVCSGMAMMRSSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J263</accession>
    <name>A0A8T0J263_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G266500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J263"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12291" checksum="1BDDBF7BDF0E9459" modified="2022-10-12" version="1">MQLQVLCQKRAQSSIILPVDPRAQGSKIFTSKAAAVLLFNKSALCRQEITYKQSRRSTAICRCPQAERLQPTLLSFEVGAARPRNGIPATFVWNMSLPIRCWTLTSRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2E9</accession>
    <name>A0A8T0J2E9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G046400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2E9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8134" checksum="E614BC52966EA973" modified="2022-10-12" version="1">MTIRGSTFHPLAVITAINGLYLLVLASSVSGENLSLQYVNSMNCMVRLGFISVGGSLWYGKPLTQRMSGLNLELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J508</accession>
    <name>A0A8T0J508_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G074400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J508"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36389">
        <property type="entry name" value="OS05G0110100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36389:SF1">
        <property type="entry name" value="OS05G0110100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035858176" evidence="2">
        <location>
            <begin position="16"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="14861" checksum="9556C56344BFF16A" modified="2022-10-12" version="1">MASLLACQAVASVAALSKVSVSKNGCATSKSQLFAPLRLKECASRGPKVVCAVGDVSAEGTNYLIAGAVAIALVGTALPVLFSRKDLCPECDGAGFVRATGSTLNANAARKDQAQIVCRNCNGLGKINQTDKPEQAAPKAKAKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J748</accession>
    <name>A0A8T0J748_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase</fullName>
            <ecNumber evidence="5">3.5.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Peptide:N-glycanase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G197100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of an N(4)-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue.</text>
            <dbReference type="EC" id="3.5.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transglutaminase-like superfamily. PNGase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.52" evidence="5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J748"/>
    <dbReference type="OrthoDB" id="409136at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000224">
        <property type="term" value="F:peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000011">
        <property type="entry name" value="peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.620.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050883">
        <property type="entry name" value="PNGase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143">
        <property type="entry name" value="PEPTIDE N-GLYCANASE PNGASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12143:SF19">
        <property type="entry name" value="PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Transglutaminase-like" evidence="11">
        <location>
            <begin position="258"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0591730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="720" mass="81042" checksum="2D1C500AEB30CBD0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J870</accession>
    <name>A0A8T0J870_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G225000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J870"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="92"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0592100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="24622" checksum="38D21409CF87F335" modified="2022-10-12" version="1">MAGKIQLYSLATPNGQKVSVALEEMDLEYEPHTINIMKGDQFTPEFIAVNPNSKIPAIVDPNGPGGKEFNVFESGAILLYLAEKTGKFLSQDPSLKWETIQWVFFQMGGIGPMFGQFGHFFKYAKDKCLDPYPVERYTNEAKRLLGVVEKRLEGRDFLIDDGYSIADMAIFPWVQCLETGYNGSEKLGLKDFPKVMAWKNRCLERPKTAKGMKVCPFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8U7</accession>
    <name>A0A8T0J8U7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G162400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36020">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36020:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="676" mass="73483" checksum="74D68773CE655C9E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD45</accession>
    <name>A0A8T0JD45_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G325700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18919">
        <property type="entry name" value="bHLH_AtBPE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000002">
        <property type="entry name" value="Basic helix-loop-helix transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024097">
        <property type="entry name" value="bHLH_ZIP_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12565:SF184">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12565">
        <property type="entry name" value="STEROL REGULATORY ELEMENT-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="512"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="327"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="371"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="603"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="133"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="385"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="434"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="484"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="609"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0593385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="731" mass="75062" checksum="05D867E960D58329" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD53</accession>
    <name>A0A8T0JD53_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G292900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD53"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039301">
        <property type="entry name" value="Sip5/DA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31315:SF1">
        <property type="entry name" value="PROTEIN SIP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="555"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="316"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="474"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="65003" checksum="4C7FFF9DC64C1594" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDA6</accession>
    <name>A0A8T0JDA6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G286500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDA6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12140" checksum="A98A930AFAF10F64" modified="2022-10-12" version="1">MHTSCTALPPWSRTFGAEISRLSHIGILLHPVCLYKPMPTPEPPRQPRGCSRLSCPSGQVRRMSFNCACEALRLATSSGAWRVAGVGLWKASVSAALENIGLLYTYVIREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G455</accession>
    <name>A0A8T0G455_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G059700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G455"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5478" checksum="8D8940F7FB0027B7" modified="2022-10-12" version="1">MLQEGKRKCKVADEQFSILYGVAVSTSGDLTSVGELKCLKRSWPKMYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5W4</accession>
    <name>A0A8T0G5W4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NLGase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G042600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5W4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000006">
        <property type="entry name" value="Non-lysosomal glucosylceramidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006775">
        <property type="entry name" value="GH116_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024462">
        <property type="entry name" value="GH116_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052566">
        <property type="entry name" value="Non-lysos_glucosylceramidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12654">
        <property type="entry name" value="BILE ACID BETA-GLUCOSIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12654:SF0">
        <property type="entry name" value="NON-LYSOSOMAL GLUCOSYLCERAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04685">
        <property type="entry name" value="DUF608"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12215">
        <property type="entry name" value="Glyco_hydr_116N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl-hydrolase family 116 N-terminal" evidence="3">
        <location>
            <begin position="122"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl-hydrolase family 116 catalytic region" evidence="2">
        <location>
            <begin position="705"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="493"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1077"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0553834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1131" mass="124972" checksum="DE55A4B116345215" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G691</accession>
    <name>A0A8T0G691_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G085400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G691"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035760204" evidence="1">
        <location>
            <begin position="19"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6408" checksum="914A0D24B309D900" modified="2022-10-12" version="1">MFILSGFLMFITIQIHQAKSPISTHSFPCLDSAAARLVFSLIYRNQILPISSCFFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCC3</accession>
    <name>A0A8T0GCC3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G187900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ROH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008511">
        <property type="entry name" value="ROH1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31509">
        <property type="entry name" value="BPS1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05633">
        <property type="entry name" value="ROH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="324"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0555679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="413" mass="46468" checksum="309B272153828305" modified="2022-10-12" version="1">MATKGSTLPRANQKKPPAGPSSKTTSDRGVDKCEVFYGSLSDKLNALEQAVQPKWLTLEWVSLAVDFMRSTFSDMMILFEDVRALMPDVKVSDEFWIEEYMVESMKLLDVCNVLKPAVSRFEHFMMCVQLVVQTVQRCSGGSQEFASDKTLMVALQSCEAELNQLVHLPLALENSAQSSSTQSENELRPTESPLRHASIALGEKFSVESININSASAQPSPVSRNGSSKSGRGTVALTLVMRATRETTDFVASVLIWALKRDPSSHPASTVWQQNLEVFRGDETLWSPSFRRLQERLRKELFEILRDERSAARRQFRQFTFEELKLVEECTADLRAEVEELAERGKSSGAQPTSLQFLENLAQDLTNLLDKIQTRLEKVSSQVNQLFDELVQARKKLLDAAQRPGTIHRTLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDT0</accession>
    <name>A0A8T0GDT0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="17">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_11G108100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16 17">
            <text>2 5-aminolevulinate = porphobilinogen + 2 H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="17">Homooctamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 18">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="17"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDT0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04823">
        <property type="entry name" value="ALAD_PBGS_aspartate_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000101">
        <property type="entry name" value="Delta-aminolevulinic acid dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006762">
        <property type="entry name" value="PRK09283.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458:SF0">
        <property type="entry name" value="DELTA-AMINOLEVULINIC ACID DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="13 17" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="14 17" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00025628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0557183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="524" mass="56331" checksum="78EEA311504654FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF37</accession>
    <name>A0A8T0GF37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_11G172900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000415">
        <property type="entry name" value="receptor-like serine/threonine-protein kinase NCRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="384"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="446"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0558016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="740" mass="82945" checksum="6BC9CDAB32A63616" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH51</accession>
    <name>A0A8T0GH51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Bidirectional sugar transporter SWEET</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G045400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Mediates both low-affinity uptake and efflux of sugar across the membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cell membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000001">
        <property type="entry name" value="Bidirectional sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000002">
        <property type="entry name" value="Bidirectional sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF30">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 11" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="69"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="192"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00037238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU910715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0558671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="31395" checksum="4FEABDF9BD78BCF0" modified="2022-10-12" version="1">MVSSGRTDDVLTVLGILGNITAMGLFLAPMPTFYKICKAKSTGQYSALPYIATLLNCMLWTFYGSHAVAGLIFVLSINVAGLIIEGCYLTIHLLFGTHSTRKKTSILLAVISILYGAIVSVVLVEFPKKGDRTEIVGSACVIFGVLMYAAPLSVMKEVIRSQSVASMPFLLSFACFCNGFIWTAFGTIKKDIFIYIPNGLGTILSVMQLVLYCVYYKKGVRKSQSSTTSALNLSQHAVDVDKLAKQPSGRVQMDQLSADSNLNQYDLSKKPDLNQNDTALVALSRDARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHU7</accession>
    <name>A0A8T0GHU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fucosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G153500</name>
        <name evidence="8" type="ORF">KC19_11G173200</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">May be involved in cell wall biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus</location>
            <location evidence="6">Golgi stack membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyltransferase 37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008107">
        <property type="term" value="F:galactoside 2-alpha-L-fucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009969">
        <property type="term" value="P:xyloglucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004938">
        <property type="entry name" value="XG_FTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889:SF86">
        <property type="entry name" value="FUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31889">
        <property type="entry name" value="FUCOSYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03254">
        <property type="entry name" value="XG_FTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0557739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="581" mass="65832" checksum="8228462F54541B14" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI81</accession>
    <name>A0A8T0GI81_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G086100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI81"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46277:SF3">
        <property type="entry name" value="BINDING PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46277">
        <property type="entry name" value="OS03G0850700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="92"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="30826" checksum="0A1FECC3130B0DFC" modified="2022-10-12" version="1">MTGTNGVDIQNSAHQNGGNVVARKERTAKEAELLKQVREKIAVLDPQSQDIDDATLLRFLRARSMDVTKGSKLFADHQKWRREYFPLGHAQEEEIKDEIAGQKYFIQGHDKNGRPLSVFLGAKHLATGSKNLEQYKRGVTYFIDKLVASIPAGEEKFNVIADLKSVKFKNLDVRGWLASYDCLQAYYPERLGKVYVLHAPTIFWGAWKMMVPFLDPVTKAKIIFVDDDKLEETLLRDISKEELPTIYGGLKEMVPMEVAQPANWPQYKPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJB1</accession>
    <name>A0A8T0GJB1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Katanin p60 ATPase-containing subunit A1</fullName>
            <shortName evidence="8">Katanin p60 subunit A1</shortName>
            <ecNumber evidence="8">5.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">p60 katanin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">KATNA1</name>
        <name evidence="12" type="ORF">KC19_10G077400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="8"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJB1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051013">
        <property type="term" value="P:microtubule severing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21748">
        <property type="entry name" value="Kp60-NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000025">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000003">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03023">
        <property type="entry name" value="Katanin_p60_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028596">
        <property type="entry name" value="KATNA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048611">
        <property type="entry name" value="KATNA1_MIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF19">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21126">
        <property type="entry name" value="KATNA1_MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="308"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="104"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="170"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="316"/>
            <end position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="557" mass="61273" checksum="A513BD0D4AD8A493" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKZ4</accession>
    <name>A0A8T0GKZ4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhamnogalacturonan lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G089400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKZ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10316">
        <property type="entry name" value="RGL4_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10320">
        <property type="entry name" value="RGL4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1120">
        <property type="entry name" value="Carboxypeptidase-like, regulatory domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051850">
        <property type="entry name" value="Polysacch_Lyase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029413">
        <property type="entry name" value="RG-lyase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010325">
        <property type="entry name" value="Rhamnogal_lyase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32018:SF1">
        <property type="entry name" value="RHAMNOGALACTURONAN ENDOLYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32018">
        <property type="entry name" value="RHAMNOGALACTURONATE LYASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14686">
        <property type="entry name" value="fn3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06045">
        <property type="entry name" value="Rhamnogal_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhamnogalacturonan lyase" evidence="1">
        <location>
            <begin position="377"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="588" mass="65816" checksum="0A4FBE415F978AFD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GL14</accession>
    <name>A0A8T0GL14_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G090900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GL14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11765" checksum="CB74EF6437745152" modified="2022-10-12" version="1">MVSLSEVFEPKGAYTPFVIPTYSASEGGNMDLTYQLGMTVNATVQNPAKREMLVNYVKNTMGYDTCDIDSRNNTVRVYNLGGLNTSAILKFIKKTIDKNATVQRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLW2</accession>
    <name>A0A8T0GLW2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Red chlorophyll catabolite reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G146300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLW2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051743">
        <property type="term" value="F:red chlorophyll catabolite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009439">
        <property type="entry name" value="RCC_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685:SF2">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06405">
        <property type="entry name" value="RCC_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="35224" checksum="67FD8236371BA2E7" modified="2022-10-12" version="1">MASALTSPSACLRIIQRSDQRLPCQRNWSELGWAQGRRNRRGLKWTVKGSMSEPAMAKETSWVEFPKLSPAGKRLMETVAETMNRELGEMILPSQTAPDVRSFQGGNGAGSVTLRAGREGSKIDFVLGSWLNCALPFGELNIATLIAMLGPEADSPHLLFEFIQSGPGSLVVVLDLLPRKDLVLEPEYLARYYENSPLETIRQAFEKHPQTQPYLTSALYVRSVVSPTALLYKLSGEGVEGGLDGVIAELVQPAAVKVVETWVDCYKNVGQDLDGDAMATMLKRDELIKSKGVEVDLSANMPRLFGQEIADRVVAAFRKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPF9</accession>
    <name>A0A8T0GPF9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutaredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G183000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPF9"/>
    <dbReference type="OrthoDB" id="418495at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd03031">
        <property type="entry name" value="GRX_GRX_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45669:SF7">
        <property type="entry name" value="F1N19.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45669">
        <property type="entry name" value="GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN CG12206-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23733">
        <property type="entry name" value="GRXCR1-2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="2">
        <location>
            <begin position="729"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="227"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="870" mass="96357" checksum="286118589403D263" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRM1</accession>
    <name>A0A8T0GRM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U3 small nucleolar RNA-associated protein 11</fullName>
            <shortName evidence="5">U3 snoRNA-associated protein 11</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G118400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in nucleolar processing of pre-18S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the ribosomal small subunit (SSU) processome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
            <location evidence="1 5">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the UTP11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRM1"/>
    <dbReference type="OrthoDB" id="29058at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007144">
        <property type="entry name" value="SSU_processome_Utp11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12838:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03998">
        <property type="entry name" value="Utp11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015952">
        <property type="entry name" value="U3snoRNP11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="177"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR015952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0559612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="226" mass="25949" checksum="52C4F027EED55B23" modified="2022-10-12" version="1">MSSLRKASKAAAGGRAHKERSQPGFRSRFGLLEKHKDYVLRAKDFHKKEQNLQKLREKAANRNPDEFYFKMVNSQTVKGVHREGSGAKVYTEEELKLLRSQDVGYLVSKAQSELKKVERLRSAVLPVSANANKHVFFVEDGDEVEGTRERVVSRPAEPLQVPRVRKKVAKEMQERTEKAAKLKDMASAVDLQRQLSGKGRKRKVRPNELENPSDLPVYKWKIERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS17</accession>
    <name>A0A8T0GS17_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G061000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="13452" checksum="28EC0D8058EDBF5C" modified="2022-10-12" version="1">MKRFSLPFRLHSAPCTNEFSRVEFLRQFSFRARQKLKQSSNAADARKLPRNPYANKFPQNLPVIHVKLTPRQNHEKRHRSSPKKRPPITTTERNHKSETKSGKRNRIIPRQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT29</accession>
    <name>A0A8T0GT29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G073900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000056">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 72B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48045:SF31">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 76B1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="506" mass="56696" checksum="068D2A7EABB529B1" modified="2022-10-12" version="1">MGPHVVMMPIFPAGHVTSFLVFARRLVSAGVTVTIISTDVHIAELKLREQATEFLRFVELRDGFEHLSVELLEEWKTDAGKAKVNRLLVEAVRDMSSPNAQALRGVPTADFPVCVMHDMVACWAQDAAEELGVEKHMLYVSPVGTLSIGLQSERLVREGRAPVTPENQNIPITDIPGLPPLQPGDFHSMYQTVESFEWFKYHEHRNRKADVIVANSFYDLEKHVIDAIRNEVMGTPGVQTKYLLDVGPLRPESPTPTALEEKDPCILWLNTQKPASVLYVCFGSHSTHHAPQLLELASGLEASGQPFLWILRPPNSVPIDASALAAPILPMTQYLPPGFEERIKGRGMCYSSWAPQRRILEHVSTGGFLSHCGWNSTLDGVCAGVPMLTWPFWADQNFISRFLVDTAKIAIEVKREPIDPEQDLGEFDRIFRRVKKSEIERQVRKLMQEEEGRIVRENMQNMKRNVERAVALGGSSRTNFEKYVQLLRAKASAAAFNGVNKLDDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV36</accession>
    <name>A0A8T0GV36_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G044400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV36"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035855227" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7727" checksum="0640DB8AD0DD90C6" modified="2022-10-12" version="1">MIITMVSPILLITSAFVMLSSEEITRLIKLSSTKYGCTPRPECMKPLLKHKSAPQHLICRCIYTFTGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWM8</accession>
    <name>A0A8T0GWM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G185200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="416" mass="49260" checksum="B851895A13FC5B89" modified="2022-10-12" version="1">MAFNPTLWSQLPLEVIEQILSFLPMPDLCRYCTTCKTWNELINNPAFSVLHVRNRNKHSPFIAIHSITTSIQNGHEVYINGSNVLCFLDICSRKWYSMKPRDALEPSFQFDPRHFQIVAMDGGLVLLKALKRTSNLCHHESGCTQLCVWNPTKDMKIILPCVPNHGNDLNDLNDLLINLIVDDIAETFKVFVIMRGWKSRVVDIYDSVMKEWKASSKLEMINRRMYIVIHSIVFQNHLYILYFSYYMPPYFDLHALYELWRYNYVADIWEGLHFAEGCFVKPLEHYVYNHGVFEQFVVSGERLFVTYRRDIPQYEFEVNEIDIQRRSTKVLLKWTKRHIMRIFDIDVLYFPNIQVIGFNKSLMLVYNLSRNIVTFDVETKKTNLEWPQLPLRKLRLEEKYSLMGKQMDFLLPGTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZR0</accession>
    <name>A0A8T0GZR0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G103700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15208" checksum="54DBC98EE236181F" modified="2022-10-12" version="1">MTSLSAPVPPLMFQSVSPPDTHCARIPSSWIVRAVRAPAPAPARTHAHTFSGTHVCLPRLLPSPAPALAMFTLHRSPLPHLQCSPSIDRIPTSPRFARSTLPCGMFTSRDYFFTCGRFGDPGECDDRASNNGVLEYLMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H093</accession>
    <name>A0A8T0H093_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G057900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H093"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000307">
        <property type="entry name" value="pollen receptor-like kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000095">
        <property type="entry name" value="protein STRUBBELIG-RECEPTOR FAMILY 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050994">
        <property type="entry name" value="At_inactive_RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010:SF76">
        <property type="entry name" value="INACTIVE RECEPTOR KINASE RLK902-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48010">
        <property type="entry name" value="OS05G0588300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035747124" description="Protein kinase domain-containing protein" evidence="11">
        <location>
            <begin position="34"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="352"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="629"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="629"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0563774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="669" mass="72952" checksum="E633510064F6A7BD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2J8</accession>
    <name>A0A8T0H2J8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G152400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the REXO1/REXO3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2J8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06145">
        <property type="entry name" value="REX1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034922">
        <property type="entry name" value="REX1-like_exo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047021">
        <property type="entry name" value="REXO1/3/4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Ribonucl_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801:SF115">
        <property type="entry name" value="FI18136P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12801">
        <property type="entry name" value="RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="7">
        <location>
            <begin position="163"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0564955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="608" mass="68183" checksum="ECE0DEA74C1CEFE7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2N0</accession>
    <name>A0A8T0H2N0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G158400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2N0"/>
    <dbReference type="OrthoDB" id="73919at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08204">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04038">
        <property type="entry name" value="C2_ArfGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000009">
        <property type="entry name" value="stromal membrane-associated protein 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044518">
        <property type="entry name" value="ARF_GAP_AGD11/12/13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46220">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46220:SF1">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="8">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="7">
        <location>
            <begin position="198"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="83"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="181"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0565037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="41349" checksum="E3969B40AD73D16C" modified="2022-10-12" version="1">MERLKKLLQQPDNRVCADCGAADPKWASTSIGVFLCIKCCGVHRGLGVHISKVVSVTLDEWSDEQVDLMEAIGGNALANSVYENSIPPDTRKPPPNASVEERSDFIRRKYEDQEFLKPNLRMKATSRTRSSATTEEDSPPAPSNRASMNSNMDSTYSSRTSSYSSTRDSIHSNSSQRGTPPGSFSSYRSSSSFAPSRKSGASLSRTSSSPSTAGMVEFLGMLKVRIVRGINLAVRDLLSSDPYVVATLGGQSAKTKVVNRNLNPVWDEELMLSVPSPPQPLRLQVFDHDVFSADDSMGEASVDLNPLIMAAQMHQGMFEEFGCEQIGRWLASSDNSLVKDSNIEVIDGLIKQDVHLKLKSVERGEIEVSLEWVPLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3Z9</accession>
    <name>A0A8T0H3Z9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G194700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably involved in the defense reaction of plants against pathogens.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.33.10:FF:000004">
        <property type="entry name" value="CAP, cysteine-rich secretory protein, antigen 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018244">
        <property type="entry name" value="Allrgn_V5/Tpx1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01009">
        <property type="entry name" value="CRISP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01010">
        <property type="entry name" value="CRISP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0568">Pathogenesis-related protein</keyword>
    <keyword evidence="2" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035806279" description="SCP domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="4">
        <location>
            <begin position="29"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="17950" checksum="EF2AC1C765424675" modified="2022-10-12" version="1">MARSWSCAILFAVLFIATGAISVAQAQAPDQAEWLAAHNAVRSAEGVGLVPFTWSTAAYNYALAWAQDRAASASCFGHSSSDTYGENIAWSSSTTATPTWAVNYWASEKANYDYASNTCTGVCGHYTQIVWNTTTSVGCASAVCTGTEGKFFTCNYSPAGNMDNRRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H805</accession>
    <name>A0A8T0H805_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G060300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H805"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="24740" checksum="D94B58DF7B30EE06" modified="2022-10-12" version="1">MPLLLQFLSFTVKLQQTSVFVHFALHFVHRIAADNNLCSLRELLHFVHRSKVWVFCSLVPLAIISMTLSVFFPTWSQPVHRRFPFQRQHSYSFETQISERILCIEQSPELKVTKAQMSCEVHLVVWPKELIFTTYVIRCYRTTQCFNECDNGDSLLHCKPRNLKLSTSVCCSNAPPPCTLIVMQNSHWNLYTEKLNSQGRKLAQNQDCSITFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB47</accession>
    <name>A0A8T0HB47_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G188100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB47"/>
    <dbReference type="OrthoDB" id="1929172at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035767864" description="GOLD domain-containing protein" evidence="10">
        <location>
            <begin position="27"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="11">
        <location>
            <begin position="36"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0568125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="210" mass="23696" checksum="65B986F291A5D971" modified="2022-10-12" version="1">MDGMGRLRWCVAVMGLLLVWGSGAQAVQFEVSSRTTKCIAEEIQSHVVVVGDYKIVHSDEAHKVTVKVTSPYGNQLHYQENVQSGQFAFTTSESGNFMACFWILNAPPTAVINVALDWKTGVAAKDWASIAKKDKLDGMELELRKLEEAVDSIHSEMLYLREREAEMRDLNELTNSRVAWFGIMSLLVCLGVAGWQLWHLKTFFERKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCH4</accession>
    <name>A0A8T0HCH4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calponin-homology (CH) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G188400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Interacts with F-actin.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCH4"/>
    <dbReference type="OrthoDB" id="431378at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032432">
        <property type="term" value="C:actin filament bundle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051017">
        <property type="term" value="P:actin filament bundle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051639">
        <property type="term" value="P:actin filament network formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21293">
        <property type="entry name" value="CH_AtFIM_like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21299">
        <property type="entry name" value="CH_AtFIM_like_rpt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000042">
        <property type="entry name" value="Fimbrin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000031">
        <property type="entry name" value="Fimbrin-2 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.418.10:FF:000010">
        <property type="entry name" value="Plastin-3 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.10">
        <property type="entry name" value="Calponin-like domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001589">
        <property type="entry name" value="Actinin_actin-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001715">
        <property type="entry name" value="CH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036872">
        <property type="entry name" value="CH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039959">
        <property type="entry name" value="Fimbrin/Plastin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961:SF18">
        <property type="entry name" value="FI19014P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19961">
        <property type="entry name" value="FIMBRIN/PLASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00307">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00033">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47576">
        <property type="entry name" value="Calponin-homology domain, CH-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00020">
        <property type="entry name" value="ACTININ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50021">
        <property type="entry name" value="CH"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="134"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="279"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="406"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Calponin-homology (CH)" evidence="6">
        <location>
            <begin position="525"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0568128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="670" mass="75263" checksum="F1D1C306A8F790FE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDG0</accession>
    <name>A0A8T0HDG0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonylcarbamoyl-AMP synthase</fullName>
            <ecNumber evidence="5">2.7.7.87</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_6G013400</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs. May regulate the activity of some transporters.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Interacts with RSC1A1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="5"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.870.10:FF:000007">
        <property type="entry name" value="YrdC N6-threonylcarbamoyltransferase domain containing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.870.10">
        <property type="entry name" value="DHBP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="Sua5-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050156">
        <property type="entry name" value="TC-AMP_synthase_SUA5"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00057">
        <property type="entry name" value="L-threonylcarbamoyladenylate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17490:SF10">
        <property type="entry name" value="THREONYLCARBAMOYL-AMP SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="YrdC/RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="YrdC-like" evidence="16">
        <location>
            <begin position="142"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0568354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="348" mass="36115" checksum="CAF2D58045D35650" modified="2022-10-12" version="1">MAPPAFSPVTLQRLHPPPASAAALRTLSSSSSEAARCKLGAATSRISSGPCSKLEGAGLGFKVPDAREGNRAGTVSASELVRCDLGARGSGFGSGSCLRPEVRSVGVGFRVWDVVRGCLGRLDSSVGVEQDEAFGGVVPANEKIYSEAVRALGNSHVVAVPTDTLYGLACDASSGEAIRRVYEIKERKLSSPLAVCVADVDVVGAYGETAHLPAGLLDSLLPGAVTLLLPRRESGRLSASLNPGVESIGIRIPDSDFIRGLSRSFGGALALTSANTSSHASTVRVEEFEHLWPHCAFVFDAGTLPGGRAGSTIVDLTQEGLFKVVRPGSVLQKTKETLAKYGLRDSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEH0</accession>
    <name>A0A8T0HEH0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Golgin-84</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G084600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEH0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031985">
        <property type="term" value="C:Golgi cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000301">
        <property type="term" value="P:retrograde transport, vesicle recycling within Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019177">
        <property type="entry name" value="Golgin_subfamily_A_member_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13815:SF5">
        <property type="entry name" value="GOLGIN CANDIDATE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13815">
        <property type="entry name" value="GOLGIN-84"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09787">
        <property type="entry name" value="Golgin_A5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="752"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="30"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="370"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="438"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="573"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="58"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="178"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="391"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="808" mass="88770" checksum="F1446153204C2F30" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFI2</accession>
    <name>A0A8T0HFI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G060100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7793" checksum="27C9F18B0688D632" modified="2022-10-12" version="1">MRKHSGTGRVVVVSGTFDHNCPRSQAPIFVTVWLILLHVVRPVSLHIAMVGKCDVRRLCEGRTTLTKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHG1</accession>
    <name>A0A8T0HHG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G031800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="9">
        <location>
            <begin position="11"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="12">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="182"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="385"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="85"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="43"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0568592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="547" mass="58984" checksum="D4A2C51596A93A93" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHQ6</accession>
    <name>A0A8T0HHQ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Vacuolar protein 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G118800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the beta-catenin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043495">
        <property type="term" value="F:protein-membrane adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071562">
        <property type="term" value="P:nucleus-vacuole junction assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045156">
        <property type="entry name" value="Vac8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47249:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1317" mass="145600" checksum="D0A97BCF6323AF2A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ75</accession>
    <name>A0A8T0HJ75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G191600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ75"/>
    <dbReference type="OrthoDB" id="275457at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05271">
        <property type="entry name" value="NDUFA9_like_SDR_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000326">
        <property type="entry name" value="NADH-ubiquinone oxidoreductase 39 kD subunit, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF11">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="78"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="406" mass="43539" checksum="C92815E3698CB62C" modified="2022-10-12" version="1">MAGALVRKAGSQSASGGARAWAAAFQQQESLLLGDHGDLGFEKSGGVRYSSSLAVSGSHRPVKRGTGGRSSVSGVVATVFGATGFLGRYVVQQLARMGSQVMVPYRGVDEEWRHLKLMGDLGQIVPMKYDAKDEDSIKAVIANSNVIVNCIGREYETRNFSFEDVNYGISNRISKLAKEHGGILKYVQMSCLAAAPHSSSRLLRSKHAAEEAVLQNFPEATILRTAPMVGVEDRLLNRWAIQAKKLPVVPIPGDGLSKLQPVLVIDVAAAVIAAIRDEGFSMGKTFELGGPDVFTVNELIALMFEAIREYPRMVHLPMALCQLLAMPREMAMKRGIPIPFSPTFSKDYLDQLACDLIVSPDAMGLADLGVTSHKIGGLTIEHLNAYRTGGPSVGTTVGESIHGAGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKR1</accession>
    <name>A0A8T0HKR1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG002800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12226" checksum="B519990770E13966" modified="2022-10-12" version="1" fragment="single">MAPSISGIANRRTWGRYTNCTVKWLTESGTTILSRRRKESCRWNIFASRAVRFTLIISSTQIYLTRKLLTRQSHESIVEIGKNTAAFRFSAKLSHSFQILREYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNS8</accession>
    <name>A0A8T0HNS8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG096300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="18783" checksum="A66D8C79372793DB" modified="2022-10-12" version="1">MLFPAGSTWIWWASKNSAKVKPAAKPNNRISRPPGSESTYTTESANKRLKCGKSGSHILGSLARIALRRKKTCETQANKALFSASIATKTQLTLTTTNTESSNDSANTQETKARNNDRTQERFTLVQSCGTSHHPTLRETYSSSQLSKAPSSNDNKARHKHSYQHQYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPU1</accession>
    <name>A0A8T0HPU1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG126900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11659" checksum="D041ED812448E512" modified="2022-10-12" version="1">MMPQLQCTCTTFGFQNCLKIISMFRILNTNLQQELLPKCGSLHLPHCLHVLFTGILRPHSQYQHLLSPTSDEQIYPARPPGELLQYKTNSARSTGWSLVHTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPW3</accession>
    <name>A0A8T0HPW3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG128000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="397"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="492" mass="56176" checksum="6633DACC1E2BD967" modified="2022-10-12" version="1">MIRVICSALYCTGSRPPGESNGQEVPRQIHRNAQEGINVISRTLRNENDLLRYQLNDIIAREKNQRIELQRLRAHRDVEVASLVQAATQQLKGEVEQMKVLLQSTSAQLLQALTEKEKAVNDSQAAVRTVDELKHNAEVQESSIMEQLRGLETVFSKTCGTVTALANSVQGFQRHVLPTFKPTGTDLTKLAQDLSHKPGSTQLMVSELARLEAGITLLRVIVDAKNDTLVLIRGKLKQENEELKAELQLSSQREQIPNIIDEKTSNSTTNEKKNYSFEKSKLHEEIQSLQDMYNAEVKHLKAKLKYQDEEEVLEKKKNCEIRHECLLLQNKIDMLEASKVILETRLKDETSARSQLVSQIFNIRKDYEKITMELETLKLNQKFLIRQPRNGRIPVEKLDLMNTINQLLLEMNKLKNEKMALEEENKIQRRCQTHDQMKRILTSRDIAMAASNKVGDGELASKLVMRRINQLTQDKTSSPFNTEVVHLGNVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPZ1</accession>
    <name>A0A8T0HPZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG138000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="12280" checksum="896794BDDDCEFF8F" modified="2022-10-12" version="1">MMGIQVDDNRMDVVNHFPVFIHCSKPNHYAILQVIFDKDDLLLQIPREIIGLPSDTIVKIHVDVPMTHTETPCFDMFFELPQCPIRLLHFSDERYIRIGFNKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQK6</accession>
    <name>A0A8T0HQK6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG159400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQK6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16095" checksum="C9F4BBF66217A805" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSIPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSQ0</accession>
    <name>A0A8T0HSQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG207900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="13196" checksum="33B5B5C598D80580" modified="2022-10-12" version="1">MPEKGGGRGNFGRGFLDFGALFATMNSSFDGMVVLVWMLMSMTLGNCATYKSRASEVLDSMNGFYFVPLLWLIATRKNRVPRIFWVEPSQATHWDYVEPIVWRATKQMHYRKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUP4</accession>
    <name>A0A8T0HUP4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG283900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="27817" checksum="A2ABD2574F436A3C" modified="2022-10-12" version="1">MEGSEKFRAKSEQMKYANACRRSKGRTGPLGEVGIRERLRHRLNRSPAPEEVVAEMTRDKGYSGARKSIRHGRSSPSESEATDSSLPFLRTEPSCEPEHPPPLPTVQDGVQPAQPFESSPPSAEAAIDTIYESTTTPVSVALALNPVFALITKQIADVQNSAVGSTEDGRALIATPESQLSTLRQRKQTVSENVSSPVTESADLLVGPMPGPTLHADAVPEQDHTVPSSRKGAAKPVSQSIPARPLVATRKSLWAASHCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVP9</accession>
    <name>A0A8T0HVP9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG302500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="10170" checksum="A46E7D9320BEFDD5" modified="2022-10-12" version="1">MVGAKTSPKLDKNVTHVLTFHNPGQELRPDWLLRSLRGEKEQELVYYGHLCHPHGQYINVVYQDWLVESLAKGFILCEMQFMAFPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVX1</accession>
    <name>A0A8T0HVX1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Fused homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_VG328700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14002">
        <property type="entry name" value="STKc_STK36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000292">
        <property type="entry name" value="Serine/threonine-protein kinase 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000223">
        <property type="entry name" value="Serine/threonine-protein kinase TIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22983">
        <property type="entry name" value="PROTEIN KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22983:SF6">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="6"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="292"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1022"/>
            <end position="1042"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="14">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00075375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0575230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1363" mass="145149" checksum="EEA6C9F554DA389D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVZ3</accession>
    <name>A0A8T0HVZ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_VG281200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000161">
        <property type="entry name" value="Dual-specificity RNA methyltransferase RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="23S RRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544:SF9">
        <property type="entry name" value="RADICAL SAM SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01062">
        <property type="entry name" value="methyltransferase_(Class_A)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="152"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0574663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="413" mass="45839" checksum="97F5D0B0DD61C64C" modified="2022-10-12" version="1">MVALVGTVAGRLIASSAGRWRTRRLVSISASVQSVAVSIVETGSEFGGGHGRVSLKEMTYPELERWVESNGHKASRADMLWRHLYGSGKWVRSPSVIPRMNKEFVSLLEERAEFAPMMELREVYTAKDGTKKLVFFVEEYGASVETVVIPGPRGRVTVCVSSQIGCAMNCQFCFTAKMGLRGNLSTAQIVEQLVVAARLCNEELGQVTNVVFMGMGEPLHNLESVIRAAEIMVSEKGLHLSPRKVTISTSGLVPQIRRFVRTSKCALAVSLNATTDEVRDQIMPINRKYNIRMLLDCVREELITYRPGEAAFIEYVMLKDVNDTEEDAARLVELVKDVPCKINLITFNSHPGSAFEPTPLEEVLKFRDRVADAGFVVHIRNSRGDDEKMACGQLGSVVPKPPRRRKQEIQVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWH0</accession>
    <name>A0A8T0HWH0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG321200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWH0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.580">
        <property type="entry name" value="Acetamidase/Formamidase-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004304">
        <property type="entry name" value="FmdA_AmdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31891:SF1">
        <property type="entry name" value="FORMAMIDASE C869.04-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03069">
        <property type="entry name" value="FmdA_AmdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141130">
        <property type="entry name" value="Acetamidase/Formamidase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="15795" checksum="222185BA66E23C41" modified="2022-10-12" version="1">MAAICYAVEKGSKDWERIATEACPTNPGRENGGNCDIKNLSRGCMVYFPVFVEGANLSMDDMHFSEGDREVSYCGAIEMSGFLELKCSIMRGVMEQYFIPMGPGKLNGNPIFEIGPASPSGWCLRASRSAPWSHASPSGCCLPSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWV6</accession>
    <name>A0A8T0HWV6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ABC transporter B family member 28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G012700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18557">
        <property type="entry name" value="ABC_6TM_TAP_ABCB8_10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000403">
        <property type="entry name" value="ATP-binding cassette sub-family B member 8, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF7">
        <property type="entry name" value="ABC TRANSPORTER B FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="129"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="488"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0575564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="732" mass="78877" checksum="A72A43FBB5DC817F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZA9</accession>
    <name>A0A8T0HZA9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Programmed cell death protein 2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G046600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZA9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007320">
        <property type="entry name" value="PDCD2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47762:SF2">
        <property type="entry name" value="OS04G0640800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47762">
        <property type="entry name" value="OSJNBB0079B02.4 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04194">
        <property type="entry name" value="PDCD2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Programmed cell death protein 2 C-terminal" evidence="2">
        <location>
            <begin position="322"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="444" mass="48601" checksum="21285D51C63B2F4D" modified="2022-10-12" version="1">MGRPLPSELVDPDDKEVVLGLPGAWAEETNEPADHYTTKIGGQPDWPVPLQDVNDELLKCGVCGGYLGLVAQIYAPLTLYGAKLDERSLFILGCPSASCGVDRNSWRTIRFQKDVPSESTSQQDQTESAAGSSTASLSGPRSGLGEALSNQGWGEDASSSQPEPPQQDPDNWWDENSWDGYAGDDGNESEAMNLQELQSSLLEAGYAAAGSRNQHHHHHHHHHHNPGRGNQGDDGGSESGEATTSNRTISESSLPSLPCFYVYTQSEQSTPYESATTRSENPAEPDPNDPLNEIEDPYGIVEGVGELWEAEDYEPDQALSADRTYLKFKKKLDISPEQCFRYCFGGRPLWATDAHDEPGTCGACGGPRVYEMQLMPPVLYFLQQAYKDLPPSAYGPNDWEWSTLVVYSCAQSCLQRAPDRAMIAGERTDWSIIVEGTILQAEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0B8</accession>
    <name>A0A8T0I0B8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G074200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0B8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11078" checksum="722FD4AAE5EFC8E0" modified="2022-10-12" version="1">MMMVFLSSSSLGYDMAREWESLDWGCCGGVTPCEPGSTWMLELGGDVLLVCLCESAAIQSLPSAIALPSAQLGLSGGVQRRGGGVEAWVCSEVGDLGRRIYACGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0Y3</accession>
    <name>A0A8T0I0Y3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Vacuole membrane protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G132500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0Y3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="52090" checksum="A08EE04700E13ABB" modified="2022-10-12" version="1">MWAGREYISASMEFEEEPKVDSNMEGEVSEVVELEADPLLQANQSDEIVDDAESVERLPVVAELKRSHTMQRERLGLLRQPIETLRLAILSLLYQCRLLWIHVLSHHLRVVGAGVLTIAIIIGLAVVDGPHEYYVREAIAYFRFAVWWIGLGVASSIGLGSGLHTFVLYLGPHIAMFAVRASQCGRVDFKARGYDTPQWGFPPSWQHRECSELGEPMFPRLPTDGLESYVVPIFKVLLQVQLEAVLWGIGTAIGELPPYFVSRAARLSGEKVKELEDLVNLPEELDHPSLYDRLKVWGLKRFSQLGFFAILIFASVPNPLFDLAGLMCGHFLVPFWKFFLATLIGKAIIKTHIQTIVVILACNPHVLEALEAGFAWVISHLPFLNRLSPSIMALVGSVKDKVSGNAGAAVPVKSGYTLGSVWNIVVQLMMAGFVASIITATAQGYLLERQKHEVSTLVEDLKKKKKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I161</accession>
    <name>A0A8T0I161_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Coiled-coil domain-containing protein 39</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G091200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003341">
        <property type="term" value="P:cilium movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060285">
        <property type="term" value="P:cilium-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036159">
        <property type="term" value="P:inner dynein arm assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033290">
        <property type="entry name" value="CCDC39"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18962:SF0">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24161">
        <property type="entry name" value="CCDC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="247"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1269"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="428"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="691"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="881"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1115"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1327" mass="150396" checksum="CCAC31B6FD89E179" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2Y5</accession>
    <name>A0A8T0I2Y5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G183200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035919565" evidence="1">
        <location>
            <begin position="18"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="42" mass="5104" checksum="58693554A37AB136" modified="2022-10-12" version="1">MLETILYLLIVCKLQWGLHQHWVLKCTVCNQFLPFCYHILEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4J6</accession>
    <name>A0A8T0I4J6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Neprosin PEP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G156400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4J6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1320.10">
        <property type="entry name" value="Outer-capsid protein sigma 3, large lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053168">
        <property type="entry name" value="Glutamic_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004314">
        <property type="entry name" value="Neprosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025521">
        <property type="entry name" value="Neprosin_propep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31589:SF223">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF239)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31589">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF239)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03080">
        <property type="entry name" value="Neprosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14365">
        <property type="entry name" value="Neprosin_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52045">
        <property type="entry name" value="NEPROSIN_PEP_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035778610" description="Neprosin PEP catalytic domain-containing protein" evidence="2">
        <location>
            <begin position="37"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Neprosin PEP catalytic" evidence="3">
        <location>
            <begin position="162"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="103"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS52045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="440" mass="49498" checksum="6DCB7DA2CAE7E82D" modified="2022-10-12" version="1">MDSHLTSSLIPRNWKQWKFWIFVCVQLLLIVGSTQADRKLQQQSANQLRQLQAHTINNNTQHAPPVMSFSVSDGSWVDCIPIEGQIAAYHPALNGHKIHTEPSSSTRRSSRVQSSHLHPQLFAREQGGCPEGSIPLKRSDSSHKFLKKSTTNGTELIIPKGNKREIHEHVTVALQQSPHSYSGSHAVFSVNGPILESEEDFSLSQLWIFDGEWDDGTWSTIEVGWQTQPLMHPHDEPLAPHLFIFWTHDAYNNTGCYDLECPGFVQVDSKWVIGGAMPSYTTLAENKSLEFEVELEVLYDPAQSVWWLYVNNDPVGYWPASIFDGRLQGSASKLEWGGEICYFREANVDVRSKTAMGSGALPLHGYPIAAYLRNISYADADGHFFDAKPSVLRRHGGRQFPLCYDIAIQENGSRDWGAYFFFGGSGLNNPVKDLREILKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5M7</accession>
    <name>A0A8T0I5M7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G174800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5M7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="17732" checksum="FCA214186D760609" modified="2022-10-12" version="1">MAHAKAMSLSSGAKTMPCWRLQYLVTTDPTCRAVNQSQQITITTDHTRLWGGAETMNKGDNAGGQGGGVGNFGPGGVAGPTAAAAAQAAQWQRSLLQRADADIGSLLDNFSHLLKAARLFAPMLMPANVAGPCTNSNCIIREDGEIQYRSELRQSPTQLAILTPSVSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5S9</accession>
    <name>A0A8T0I5S9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G049800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TFB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5S9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000439">
        <property type="term" value="C:transcription factor TFIIH core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027079">
        <property type="entry name" value="Tfb1/GTF2H1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013876">
        <property type="entry name" value="TFIIH_BTF_p62_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12856">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIH-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08567">
        <property type="entry name" value="PH_TFIIH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BSD" evidence="9">
        <location>
            <begin position="201"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="417"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="531"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="615" mass="67586" checksum="24ACC434F10DF996" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I791</accession>
    <name>A0A8T0I791_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G011900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I791"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006820">
        <property type="term" value="P:monoatomic anion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016688">
        <property type="entry name" value="MscS-like_plants/fungi"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618:SF23">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31618">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0578293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="608" mass="67850" checksum="DB1AD64669982FB4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7N6</accession>
    <name>A0A8T0I7N6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G070200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7N6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.120">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040400">
        <property type="entry name" value="BAG5/6/7/8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036533">
        <property type="entry name" value="BAG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33322">
        <property type="entry name" value="BAG DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33322:SF4">
        <property type="entry name" value="BAG DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00264">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51035">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="154"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="285"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="631"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="653" mass="72599" checksum="2154AC8C01252252" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I947</accession>
    <name>A0A8T0I947_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G153700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I947"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6130" checksum="2E8854C6E33C8FA5" modified="2022-10-12" version="1">MTSETTHLETRVLFFAATVRSYTSQGRCKEQPKAKLQKIDTNQAEEPLSKEGPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAA3</accession>
    <name>A0A8T0IAA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transmembrane protein 234 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G129100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3730.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018908">
        <property type="entry name" value="TMEM234"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28668:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10639">
        <property type="entry name" value="TMEM234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="140" mass="14718" checksum="6843E2163372ED38" modified="2022-10-12" version="1">MAVVGWLLAIGTVWGITNALIKRGALIADEAKRTAAAKTENSERSMLGSFLGDWIQLLCVWQYSLPFLLNLSMSVLFVIKLGDSPITLAVPVTNATTFAVTAVAGAALGEKMRALETLVGVVLIVAGVTLCISPPIKGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBW8</accession>
    <name>A0A8T0IBW8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G234800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="26579" checksum="EED8EE0EA1A06BF0" modified="2022-10-12" version="1">MAEPQPDQFVCEIMGRSLENVRDWEGVANIDTVDESLLNAKNSVWIKQNSLYSEAHQNWEGLNKATGERLERREKRSEELTNQIYNLVGFFSVFQGVIFTAVTQLTQSTQPAPVGCPSRPPLCRKVWVPVVLSGLAAIVAAVGIWLKFSALHSIDKHIHIEFLDQREARRKLSKLQGEGHEFKFSKLKKPEKPKDTERSHWILKAILVILTVVAFTLIFIMSYFVILCDKFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBY7</accession>
    <name>A0A8T0IBY7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Annexin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G175100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="domain">
        <text evidence="7">A pair of annexin repeats may form one binding site for calcium and phospholipid.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the annexin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBY7"/>
    <dbReference type="OrthoDB" id="37886at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005544">
        <property type="term" value="F:calcium-dependent phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001786">
        <property type="term" value="F:phosphatidylserine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000001">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000002">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000003">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.10:FF:000005">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.10">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001464">
        <property type="entry name" value="Annexin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018502">
        <property type="entry name" value="Annexin_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018252">
        <property type="entry name" value="Annexin_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037104">
        <property type="entry name" value="Annexin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502">
        <property type="entry name" value="ANNEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10502:SF102">
        <property type="entry name" value="ANNEXIN B11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00191">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00196">
        <property type="entry name" value="ANNEXIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00335">
        <property type="entry name" value="ANX"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47874">
        <property type="entry name" value="Annexin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00223">
        <property type="entry name" value="ANNEXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51897">
        <property type="entry name" value="ANNEXIN_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0041">Annexin</keyword>
    <keyword evidence="4 7" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 7" id="KW-0111">Calcium/phospholipid-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0580457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="314" mass="35306" checksum="337A459DC40673D0" modified="2022-10-12" version="1">MSTITVPSYLSMSEDVHGLYRAFKGFGCDEKKVIQILAHRTQLQRLAIADAYHGQYGESIHKRLKSELHGKLERAMLLWMMGAAQRDAMLIYEATQGLGTKDSALIGIICTRTPSQIYEIKQAYHAMYHQALERQIDGDTSGDYRKLLLALVRGNRSETLAVDPNLALGDAMELYRAGEGRLGTDEEIIIHILTTRSPTQLNMALQYYRQNFGHDFEKAIKKEVSGRFENALLALVQGVCYPARYFAQELVDATKGLGTKEEGLIRVITTRAEIDMYYIKQEFLAMTRRTLEAVIASETSGDFQHFLLSLVGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICQ9</accession>
    <name>A0A8T0ICQ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GPI-anchored protein LLG1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G194500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058888">
        <property type="entry name" value="LLG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039307">
        <property type="entry name" value="LORELEI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31533:SF2">
        <property type="entry name" value="GPI-ANCHORED PROTEIN LLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31533">
        <property type="entry name" value="GPI-ANCHORED PROTEIN LLG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26578">
        <property type="entry name" value="LLG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035720999" description="GPI-anchored protein LLG1-like domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="GPI-anchored protein LLG1-like" evidence="3">
        <location>
            <begin position="55"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF26578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="17940" checksum="503A4077062B4895" modified="2022-10-12" version="1">MAATALRSVQLGLVGVVAFLSVVVSAAGNGDNEAGAMVAGIPTRHLLQTVQPCPVDFATQNYSVVTSVCNATNPNMPVCCQAFVEFACPFASYINDANTNCNVAMFTYLNMAGGYPEQMFTTCQGDANGLPCPVVPEPSPNPSSATMDMPWRLSSLVILLVTLVHLVRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICW9</accession>
    <name>A0A8T0ICW9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">30S ribosomal protein S9, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G202800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000034">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_uS9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035758436" description="30S ribosomal protein S9, chloroplastic" evidence="5">
        <location>
            <begin position="21"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0580825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="261" mass="28770" checksum="D10F9D22F5E8D5B9" modified="2022-10-12" version="1">MASLARLRSLLLPLRHNAAAAAAAANSSFLERPTLLPLLHRNMFSSRSFSGAGEHEPPPAPGTFGHLLAQSGLTEDALDSLIALKDFTGIEGLPPLELIEEMDPEGEKKAMRREIERRKQEEIDKTRVKTVDEFGRAYATGKRKESIARVWLAQGEGKFTINGKAFDNYFPDIANRIHMLEPLVQTNTLGAFDVRSTVKGGGTTGQSGAIRHGISKALQLFDPSLRPLLKSAGMMTRDARVVERKKPGKAKARKSYQWVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDU2</accession>
    <name>A0A8T0IDU2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G221100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="9068" checksum="CC917AE52F750A3B" modified="2022-10-12" version="1">MDGLWNPFISFRLDFRIYTRLPRRVVVGEDRHTNLEYLASRPATCDTHLTSTEEIVLDVHLHIIHVNTSTYQSPLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDY4</accession>
    <name>A0A8T0IDY4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G192900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDY4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042392">
        <property type="term" value="F:sphingosine-1-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969:SF13">
        <property type="entry name" value="AT30094P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14969">
        <property type="entry name" value="SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="3">
        <location>
            <begin position="115"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="303" mass="34669" checksum="911C377A35130D82" modified="2022-10-12" version="1">MRITRAAGTRRSPSRGRRGRLASRSRSKSRSRAKLKNTAISADDLPSCNRRGWVDRIVDYDTNFSYWIHEQGLQFFFYMVLRILEFSGEGLFLIPAAAAAYLLPKGKLNPEVRMFFFNLLGAFIVDLVIVTLIKNYVRRRGPMYCHVHHVTGEDRSFPSGHSTRALMVVTFFTMYLPMWRVQAANVWLPFLKRVLSNEVRILDEGVPMLESFLVSVVTWLVFSWAVATTSSRIILGRHFFFDVLVGCLVGTLESILYNNFLVIPHAVSEAVHSYISSFFGNIEEVLARFFGGASMYIQSWVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE53</accession>
    <name>A0A8T0IE53_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G270600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE53"/>
    <dbReference type="OrthoDB" id="508259at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33344">
        <property type="entry name" value="OS02G0761600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33344:SF1">
        <property type="entry name" value="OS06G0214100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="2">
        <location>
            <begin position="204"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="307" mass="34278" checksum="C730826A38B8E01D" modified="2022-10-12" version="1">MAHLLADFTGRFRGCSYKRATFVLCTGNVMMALFMLHAILAPICSDSSPPQRAHGVLSDGLTVAPTKEEWQRIEDSNRLRLKLLPTLLIERVNEIRLETEEEIERTEALNLEKLNVAAKLAERLRELKLGNSQSTLQALEEWKKRKVEKRNSVTAAARDDEQIAAYLGVSADDLQLGSQQNAGLEDDTIPGREIPPECHAEVHTDYGGAAVRWGLTHHVGSAADCCQACLDHAKNATAEEKKCNIWVYCPSEGGCHSPDKYTHENHECWLKQADEPVLNFKDHYSEEYRQQHPAAPSVVPWISGVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEF0</accession>
    <name>A0A8T0IEF0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G247200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEF0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035888943" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="81" mass="9131" checksum="A9D9098F4DF876F7" modified="2022-10-12" version="1">MMYVCVWTLDSVTRILCRLFVTNSWCVLGNPGASFSRFNQLRLSSICCFSYSHLKGCVVYCSGDVASWVIVFCILTSLTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEI6</accession>
    <name>A0A8T0IEI6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1279 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G036800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEI6"/>
    <dbReference type="OrthoDB" id="426386at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045866">
        <property type="entry name" value="FAM210A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009688">
        <property type="entry name" value="FAM210A/B-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21377:SF0">
        <property type="entry name" value="PROTEIN FAM210B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06916">
        <property type="entry name" value="FAM210A-B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1279" evidence="1">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="14631" checksum="9E3F93433C0C97DB" modified="2022-10-12" version="1">MAGALSLGRFKELVAKYGKVALGVHLSVSAVSVTCCYAAIKNNVDVGAVLQSVGLYSSSMEKEEAEDIQKYEAVALEGAQIPKEEDRKSAVHAAVSGGGALALAFLCNKALMPIRVPITVALTPPVARMLARRNLYKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEZ0</accession>
    <name>A0A8T0IEZ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G222300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035935500" description="Hydroxyproline O-arabinosyltransferase-like domain-containing protein" evidence="8">
        <location>
            <begin position="29"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="773"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="9">
        <location>
            <begin position="54"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="9">
        <location>
            <begin position="398"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0581068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="808" mass="92537" checksum="10F9760B6C8D852C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHS1</accession>
    <name>A0A8T0IHS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cysteine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G034800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000009">
        <property type="entry name" value="Cysteine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1910">
        <property type="entry name" value="Cysteine-tRNA ligase, C-terminal anti-codon recognition domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056411">
        <property type="entry name" value="CysS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890:SF25">
        <property type="entry name" value="CYSTEINE--TRNA LIGASE, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="CYSTEINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23493">
        <property type="entry name" value="CysS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA synthetases class I catalytic" evidence="12">
        <location>
            <begin position="97"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Cysteinyl-tRNA ligase anticodon binding" evidence="13">
        <location>
            <begin position="529"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF23493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0582108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="580" mass="64819" checksum="0E6E2A7599977E57" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHV8</accession>
    <name>A0A8T0IHV8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G065000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHV8"/>
    <dbReference type="OrthoDB" id="10256793at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000005">
        <property type="entry name" value="Chaperone protein dnaJ 1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000037">
        <property type="entry name" value="Chaperone protein dnaJ A6 chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.230.10:FF:000002">
        <property type="entry name" value="Molecular chaperone DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000009">
        <property type="entry name" value="Putative Mitochondrial DnaJ chaperone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.230.10">
        <property type="entry name" value="Heat shock protein DnaJ, cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008035">
        <property type="entry name" value="PRK10767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF22">
        <property type="entry name" value="MOLECULAR CHAPERONE HSP40_DNAJ FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="DnaJ/Hsp40 cysteine-rich domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="541"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="14">
        <location>
            <begin position="84"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="15">
        <location>
            <begin position="224"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="11">
        <location>
            <begin position="224"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="443"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="502"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0582501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="578" mass="61339" checksum="51A5B57BA8D78525" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIP2</accession>
    <name>A0A8T0IIP2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G086000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035735242" evidence="1">
        <location>
            <begin position="17"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="32" mass="3722" checksum="4293628F94EA0466" modified="2022-10-12" version="1">MFFLTLFAICFGEVELACCCDSVVDIYDLVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJV2</accession>
    <name>A0A8T0IJV2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G119600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11871" checksum="EDB0CF35F16E139E" modified="2022-10-12" version="1">MSCPVLSEGAVRLRCFLLLLVSCRKEGRKWVPKLPGAVQCSDLGFNRLRPAERHRKAPSCIQSGNYLALVLRDCLHFIYLVASALHCIALHSHEGILVRSPTHNPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL13</accession>
    <name>A0A8T0IL13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Isocitrate lyase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G112900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in storage lipid mobilization during the growth of higher plant seedling.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Glyoxysome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009514">
        <property type="term" value="C:glyoxysome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.850:FF:000001">
        <property type="entry name" value="Isocitrate lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018523">
        <property type="entry name" value="Isocitrate_lyase_ph_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01346">
        <property type="entry name" value="isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631:SF3">
        <property type="entry name" value="BIFUNCTIONAL GLYOXYLATE CYCLE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="ISOCITRATE LYASE/MALATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00161">
        <property type="entry name" value="ISOCITRATE_LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="7" id="KW-0330">Glyoxysome</keyword>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="106"/>
            <end position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="216"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="436"/>
            <end position="440"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0583143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="566" mass="62953" checksum="C929C5A93272532D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM16</accession>
    <name>A0A8T0IM16_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G172000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM16"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="272"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="425" mass="48309" checksum="E0FD96D93B0CCA98" modified="2022-10-12" version="1">MDSLPALHPIVLDHISSRPFKYSPKGLTFNGYPREDIADLKRDLFPKRKNAASLNKNKNKDWWVAQLRLYGINDVKASVKKEELIAALKRSLRGLSGPPEDLLQLEQKLARKFLLENAEAREKEYVTLSEEKRAEKYSDRYLREKFCNGTENETLVALAIGLSSSSVHHAATKLGLHCETTCGPEQRMWTIIGKKQSEVRKRTAAIGKEFQEWESEERDVKRRKVEIRRQGCEAGGAGCFKEVEGEWNIECPKMDEQWSDLGQRRMSIFFQKPSARRHMSDDEDGYPSSDFDDDDEAEAEEHDGASEVDDSPILCANFKMGIVNGMLRSKGDLPAQSSSFPVPKVPFTWRGAETGEGMIELDYQGNINVGSFSFVTKTQLNGVFKNDLGKWPFTGFKVAKTPADTEDTWEDYSEEAYERARVGRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMD3</accession>
    <name>A0A8T0IMD3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1499 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G188100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMD3"/>
    <dbReference type="OrthoDB" id="41501at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010865">
        <property type="entry name" value="DUF1499"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34801:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07386">
        <property type="entry name" value="DUF1499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="238" mass="26278" checksum="5B9E23DFB9BF7A88" modified="2022-10-12" version="1">MPSTLLVGSSFTGSKLQIQSVVEKVAAADVSNASPGRTVCQQKGSDRKAASGKMQSETLPTKVSRRETILRSSGSALMLAFLNFAGERPDYLGVQSNPPSLALCPPTPSCISTSEELNDPTHYIPPWTYNPQDGRGRKNPASKEKAMAELIDAINTTKPDNFSPRIVKQTDDYIYVEYSSPLVGFVDDVEFWFPPGNRSLVEYRSASRTNGIDFSFNRKRIKALRQALERYGWESIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INM7</accession>
    <name>A0A8T0INM7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G190900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053334">
        <property type="entry name" value="Chloroplast_Sensor_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48206">
        <property type="entry name" value="CHLOROPLAST SENSOR KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48206:SF1">
        <property type="entry name" value="CHLOROPLAST SENSOR KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035926585" evidence="2">
        <location>
            <begin position="19"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="357"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="590" mass="63558" checksum="26A982A6676A42DC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPG2</accession>
    <name>A0A8T0IPG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Large ribosomal subunit protein uL4 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G230600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1370.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025755">
        <property type="entry name" value="Ribos_uL4_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_uL4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_uL4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013000">
        <property type="entry name" value="Ribosomal_uL4_euk/arc_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_uL4_euk/arch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14374">
        <property type="entry name" value="Ribos_L4_asso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="Ribosomal protein L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00939">
        <property type="entry name" value="RIBOSOMAL_L1E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL4 C-terminal" evidence="5">
        <location>
            <begin position="383"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="454"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0584726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="508" mass="56163" checksum="8B19926229431FF0" modified="2022-10-12" version="1">MKNSSNIRVYHAHQTTWRRRRRQQPTGNKEYQRENRESERTARMELMGTRERGSDGGGGGWGQNPNGGRRGSGERARGGSGERDGLFRVHLEVAGLSERGAQRFAMAQPAARPLVTVQSTDGGEKGVQSTLPAVFLAPIRPDVVATVHTALAKNKRQAYAVSHKAGHQTSAESWGTGRAVSRIPRVPGGGTHRAGQGAFGNMCRGGRMFAPTQIWRRWHRKVNLNQKRYAIASALAASAVPSLVLARGHKIEEVPEVPLVLGDSAEAIEKTSAAVKLLKSLGAYADVEKVKASHAIRAGKGKMRNRRYVSRRGPLVVYGTEGAKLVKAFRNISGVEIVSVDRLNLLQLAPGGHLGRFIVWTKSAFEKLDAIFGTHEKKSLIKKDYILPRNIMGNPDLGRIINSDEIQSVVRPTKVAIKRRALKKNPLKNLGALLKLNPYAKTARRMELLSQERQAKAKAEKLQSKRSQLKPEEKELIKKQGASWYKTMVSDSEYTEFENFTKWLGVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQL5</accession>
    <name>A0A8T0IQL5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal RNA-processing protein 7 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G260700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RRP7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQL5"/>
    <dbReference type="OrthoDB" id="5390at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032545">
        <property type="term" value="C:CURI complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034456">
        <property type="term" value="C:UTP-C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12951">
        <property type="entry name" value="RRP7_Rrp7A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040446">
        <property type="entry name" value="RRP7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024326">
        <property type="entry name" value="RRP7_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13191:SF0">
        <property type="entry name" value="RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12923">
        <property type="entry name" value="RRP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 7 C-terminal" evidence="4">
        <location>
            <begin position="55"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="60"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="14"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0585126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="179" mass="20241" checksum="7141A2C557FC2017" modified="2022-10-12" version="1">MVAMKSRLKSPHGAAKPDAATNATDAATQLSERAPDSTTPEPLQGMKKWIANYKAKRPGVEVLQRQIDQWMADYDARELEAKRDRETAEAEDGWTVVVAKTGRKKTTDETGLSVGAVALEAAEDRGNKKRKKKADAALDFYRFQRHEARRNEVLELQERFQEDKKRIAALKAARKFRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR37</accession>
    <name>A0A8T0IR37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G238600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000057">
        <property type="entry name" value="Heat shock transcription factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF427">
        <property type="entry name" value="HEAT SHOCK FACTOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="11">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="352"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="153"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="352"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0584843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="515" mass="57789" checksum="2D3271B04CEF1BC1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISF3</accession>
    <name>A0A8T0ISF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G024100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="225" mass="25209" checksum="EE8A916C16277346" modified="2022-10-12" version="1">MSIPRQRFVGNLHSLMSNDLSIWQALLVVWLISVSIHKFSGAAVEILEQWFLNSFEEESSSQGEPAGLVAQTEAPSPLSDEVGEDSPGAADKPLGSLIPSLPDAVVREQVWPVLVSNPSVTQLLHFWHINSSWSRFVGSTLEWKTLIFVMLDFPEYLQHVRQQGLIFLSATLRLGLEIAHYRLLVRESMEEGDTCSRGDLRLWPRGIEGWGQGTRRSLGGQPHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISU7</accession>
    <name>A0A8T0ISU7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G043000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="6314" checksum="64B12DF641CEF4A2" modified="2022-10-12" version="1">MLNWWIQQVRCQMTLCVLSRLLNYYPSRTKLQARTSPDKQRPDTQSCLIQSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUM8</accession>
    <name>A0A8T0IUM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G062700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080043">
        <property type="term" value="F:quercetin 3-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080044">
        <property type="term" value="F:quercetin 7-O-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000056">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="486" mass="53030" checksum="6ADF1D857BAA0F23" modified="2022-10-12" version="1">MEIADGAAAPAPPHAVLFPFSTLGHVRPVLQLARRLAYVHGFKVTVVTTSYIYKRLGFAHVTSADDNLQHIDLGEGFPESYYTVDTMMRVLMVALTTLGPLVKELLGSILPITCVISDMSCNEAHKAALHYGIPSVALSCQSASASSSKYYGPRLVAEGLLPLPKDETARKETLSKLVTCVPGMYPMTLGEYHTGLLMEGFSKYLTGEHSASLHKRAWILQNTVHELEAEVIEAMEQDAGIRLLSVGPLAIAPMTLNGSIRADDDDNSTTSFWPEESKCMDWLASHSPVSVVYASFGSLASIVPSVLEDILLGLETSQVPFLFVMRADLTRSLAASLQGFQERTKDRGLIVAWAPQLRVLSHPAIAAFLTHCGWNSILESVSAGVPMLCYPCFVDQLMNNRFIVSVWKIGLELEKRADGSLDQVEVSTRVRAVAAKDSEMRVNANTWKDVTRRAIQPSGSSHNNMLTFVADMYKRAASNAATLITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWR7</accession>
    <name>A0A8T0IWR7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G181300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="20189" checksum="C7B961BFAC5883C6" modified="2022-10-12" version="1">MGVYEQGTSNGQTEPVMGHPVYPPPVAFTQPLPAQMQVPPVRAVVPEGCTGQWNASLCGCCSDCDMCCQTCWCPCVTFGQVAEVVDEGQGSCCVQATIYGLLCSVGIPCVYSFMWRQKLRQKFKLERGCCGDFCVHCCCAWCALCQEHRELRSRGLDPSLGWEVAQQTYFRPMAVPTPPGAMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXA9</accession>
    <name>A0A8T0IXA9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ArsA/GET3 Anion-transporting ATPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G155900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the arsA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXA9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043529">
        <property type="term" value="C:GET complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071816">
        <property type="term" value="P:tail-anchored membrane protein insertion into ER membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02035">
        <property type="entry name" value="ArsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000235">
        <property type="entry name" value="ATPase ASNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03112">
        <property type="entry name" value="Asna1_Get3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025723">
        <property type="entry name" value="ArsA/GET3_ATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016300">
        <property type="entry name" value="ATPase_ArsA/GET3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027542">
        <property type="entry name" value="ATPase_ArsA/GET3_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00345">
        <property type="entry name" value="GET3_arsA_TRC40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803">
        <property type="entry name" value="ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10803:SF3">
        <property type="entry name" value="ATPASE GET3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02374">
        <property type="entry name" value="ArsA_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ArsA/GET3 Anion-transporting ATPase-like" evidence="10">
        <location>
            <begin position="24"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="31"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0587321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="41279" checksum="C0583130B083F98E" modified="2022-10-12" version="1">MADLEELPMPEASVQNVLEQKELKWIFVGGKGGVGKTTCSCMLATLLAQVRESVLLISTDPAHNLSDAFCQKFTKAPTMVNGFSNLFAMEVDPTVESEDLEEQADGLGMGGFVSELANAIPGIDEAMSFAEMLKLVQTMDYSVIVFDTAPTGHTLRLLQFPSTLEKGLEKVMSLKSKFGGLIGQVSRMFGAGEEFGEDALLGKVDNIKAVIEQVNEQFRNPDMTTFICVCIPEFLSLYETERLVQELARFEIDTHNIIINQVLFQPDVSDSKLLQARVRMQQKYLDQFHELYEDFHITKLPLLPEEVRGVESLKSFSKNLTKPYIPEEGKEGVGAGRIRELEEEVASLRATMTSLQSELEKLRDGHKAPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXG5</accession>
    <name>A0A8T0IXG5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G161300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16042" checksum="1C92C808F0CD618D" modified="2022-10-12" version="1">MATHDSAASAAFPPPVGTLTPANPLPQTASTPLIGNVPPQAVEGLKAAAHQAASILPLEPTQVHTLFHLISPQPTHTWVHHFQLILKWNVYLVTGAPGTAGLDSNDTSDSPRRPSCRIHGGLSWESPSLSEGQHWEAKIVCSNRFRLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYK6</accession>
    <name>A0A8T0IYK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G233800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYK6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF8">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="237" mass="26881" checksum="AFAE7EEC2EFFFBD9" modified="2022-10-12" version="1">MALPICANIDLTKILLLKYSKTKVQWNCPVYAVKMLEEATHADITFEVAAGGSVKAHRDVLANVSPVFAAMFRHDMKEKLTTTVKISDMTIDGLKLFLILLYTTKDVNDAGIEALNDAVDKYFPEFHNAMKKYQVESTLGSLYICALERNLNRDNCWIYYQSFTKGSAIGSVTCYKYILEHYDEVIMSNNFLETMKQDPGWVCHVVRDASSEASCAWALKNFMAALKRRRTEATIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZL9</accession>
    <name>A0A8T0IZL9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 tensin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G241600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZL9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10409">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 tensin-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="10080" checksum="EA3F0C33068299E4" modified="2022-10-12" version="1">MQQKCICYDVQPTWVAGDVKVEFFERKFQRQLSLFYTWFNTIFVDSNQFALASKDKLDRPSSNLDTSFQVFLSCSTYSSMYLQCAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZS9</accession>
    <name>A0A8T0IZS9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G246300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02249">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050715">
        <property type="entry name" value="LRR-SigEffector_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752:SF195">
        <property type="entry name" value="LEUCINE-RICH REPEAT (LRR) FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0611">Plant defense</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="8">
        <location>
            <begin position="1342"/>
            <end position="1404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0588482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1414" mass="158973" checksum="F493B1CAB2CD1B05" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J097</accession>
    <name>A0A8T0J097_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G240800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J097"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035753843" evidence="1">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="91" mass="9802" checksum="E63BE709F3EDC674" modified="2022-10-12" version="1">MARIQVLVCVFVLAVLLVSPCSAARELRGDLHGRRLSPSVRRSLNTGDDGVPAVAKVAENQSKYNEWVHFQAEQLAADYPPAAANPSVPCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0S1</accession>
    <name>A0A8T0J0S1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G028900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035721003" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5346" checksum="ABA3EBE1CDE7E20D" modified="2022-10-12" version="1">MLMLVVVTVSLAVLASTAQAAHPNAQKLKLDFYKTRCPPLPSAESHKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1G9</accession>
    <name>A0A8T0J1G9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G288600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="7834" checksum="CBBD802AD65F4480" modified="2022-10-12" version="1">MAKTTSNSTPLELYNRSARFHLHKMLPFTSNCPQEPPLLECTTTQAPTIHIIIHQPCPSQSTTSPAATEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J365</accession>
    <name>A0A8T0J365_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G062600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J365"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10227" checksum="340F80CB3F3F1603" modified="2022-10-12" version="1">MHPLRGTVSLLSSLITFTSNLFSLQLSFYLLQTDQHEVLSHSQIYKLHFSSQELYGGRDHVLGSSEFDGGEELLFVLSISWFSVARFLLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J602</accession>
    <name>A0A8T0J602_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G139200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J602"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11963" checksum="539FAA6DF448BBB2" modified="2022-10-12" version="1">MVGSMYEQCFLFPGVCEVWDMVDIRSGCFRAVLDVKLAGVSWCWSLFLGVFEILGMNLIVWMGGCGGGIWWGRGFTESVWGQRSGYYHMISLHDSYGYIVGHKSCGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6U9</accession>
    <name>A0A8T0J6U9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G169700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6U9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035947755" description="Bulb-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="56"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="23213" checksum="105D1BDD34454373" modified="2022-10-12" version="1">MKSFLLLVGVLLQSFCFLTASGQPNFDNDYSLGNSTYTDIPIVPFGGYAGFNSILVSNLTYCALVTRNSDVSSGQGPICYLEVNSIELVNRTHYWTKPCPATPQQLAPGSASWCQFEFTQDGNLLLKSGLTNVSVANGTVLWSSNTSGLGATSLALLDSDPASGPGNLVLYNANKEILWSAIGNSSASEEYHCSYENYPTLAPAPAPSPSAGRKLLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J860</accession>
    <name>A0A8T0J860_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">High mobility group B protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G206900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J860"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16872">
        <property type="entry name" value="ARID_HMGB9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22009">
        <property type="entry name" value="HMG-box_AtHMGB9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045303">
        <property type="entry name" value="ARID_HMGB9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691">
        <property type="entry name" value="HIGH MOBILITY GROUP B PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="4">
        <location>
            <begin position="82"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="329"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="329"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="309"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="531" mass="58448" checksum="46760A3ADB3A3B0D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J876</accession>
    <name>A0A8T0J876_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G175000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RETICULATA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J876"/>
    <dbReference type="OrthoDB" id="497268at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021825">
        <property type="entry name" value="RETICULATA-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31620">
        <property type="entry name" value="PROTEIN RETICULATA-RELATED 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31620:SF15">
        <property type="entry name" value="PROTEIN RETICULATA-RELATED 2, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11891">
        <property type="entry name" value="RETICULATA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="73"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0591422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="387" mass="40412" checksum="5E55AF7421D869BF" modified="2022-10-12" version="1">MTTSMMTATLGSRAAPTLCSRPAIRRPNPARYGQQGATSVAVFSPSLRCTPASPSSHLEHGKRLYTSLSLLERKSQPSTPHVISRSSTSGSLELADGGGGNPGQGGGREGGGGGGGDDGKGDEYGDNNYEDAGKAGLLEAFRRGWRRRVRADPQFGFKVFSEVVIGVAACVLGDMASRPNFGLNELDFVFSTIVVGSILNFTLMYMLAPTAAVGQASQQLPLLFAACPPGHMFEAGNYSLLDRVGTFVYKGVQFAAVGFVAGLAGTALSNLLLAIRKKVDPKFEIQNKPPPTVLNALTWAGHMGLSSNARYQTLNGLEFALAGILHPTAFKSAVFVLRGVNNVCGGVTFVMLARKTGSQTAPAPSPAASDVATSDAKEGLLLAEQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAJ5</accession>
    <name>A0A8T0JAJ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G260700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12973" checksum="3783E6BCCA072EB8" modified="2022-10-12" version="1">MCSGPTFLEVGDHHLETVLRPFESFTCKTKHGLAPSRQITEISNTRLLHHTKEDQRQYWASALTVELHAASHLPHSFDDQGRRILRPDRSGPVLLTLAFFSSTDYAPSRFLETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC27</accession>
    <name>A0A8T0JC27_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G332000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF194">
        <property type="entry name" value="INVERSIN-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="14"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="47"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="113"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="146"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="179"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="212"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="278"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0593464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="334" mass="34991" checksum="5649F68D4E591A64" modified="2022-10-12" version="1">MAMAMAGTMRSHADGTTDMHKAARDGKWETLRELLEAFEDPNVRDKKSKTPIHEACAQGHEECVKLLLDYGALSSAHKTNGFTPLHYAAAGGHISIVHLLVSRGAAVDGGDHKGERAIDVAARSGFINVVQALLENGANANTQTNNGRSCMHTAALHGHIEVLRMLLDAGGNPCLKDNGGGQPIHEAAGGGHVECLELLCSRGADAAACDACGCTSLHRAASGGHVVAARWLIKNGVDVEAKDSKGSTALYWAASRGQADMVLFLIQEAKANPSAANVYRSPLHVAAGWGHVEICKLLLKAGADVNARDRDGLTAGDVARNSTQFPGLAEVFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCQ1</accession>
    <name>A0A8T0JCQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G272200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="18707" checksum="23023B513186301D" modified="2022-10-12" version="1">MHTAPWLLCCHGNSHVRLAWCVSAKERFSQFYWQKKVSYTCTAMGIVGPKTLLLGLVVAVLAVAAAQASVTVYNPAGLLVDILVDDKNVKVTSEMMTLNVTQGQQNIKFQVSEGEAMEVSVQDGDVLVLIPDPSNPLHAVLALKVQEGGVEFGSELLAPPLASPLPEVESTPALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD61</accession>
    <name>A0A8T0JD61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G295400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="177"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="211"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="381"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="415"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="574"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="603"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0592982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="863" mass="97384" checksum="6B13248441399E10" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G506</accession>
    <name>A0A8T0G506_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(A) RNA polymerase mitochondrial-like central palm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G085500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G506"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05402">
        <property type="entry name" value="NT_PAP_TUTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054708">
        <property type="entry name" value="MTPAP-like_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271:SF134">
        <property type="entry name" value="NUCLEOTIDYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12271">
        <property type="entry name" value="POLY A POLYMERASE CID PAP -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22600">
        <property type="entry name" value="MTPAP-like_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81631">
        <property type="entry name" value="PAP/OAS1 substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Poly(A) RNA polymerase mitochondrial-like central palm" evidence="2">
        <location>
            <begin position="92"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="624"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF22600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="660" mass="74318" checksum="97A12B23894ABF59" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5H1</accession>
    <name>A0A8T0G5H1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G097800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5H1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="224" mass="23910" checksum="842391BA46D3B782" modified="2022-10-12" version="1">MAHAHCDGSLQNQNQGSFHIKGQGSFFHAIWAWSGLHLSYFINICSGIKRGQILMTERLPPGEAIAGHLDTVLAPLVLLGAKGVTGLKLKPARHLQEHNSILLLICSLSFLIPGAHAELKSNEAASISICVCAPPRVWEISDHTLKVVAVTILAAITTIGVAVAGRSRFNLRSPVGQTIPHHGPEIQAISAALPIIPVVQGDDLDDVLARAPIPTRLNSPLSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5K1</accession>
    <name>A0A8T0G5K1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G083700</name>
        <name evidence="2" type="ORF">KC19_12G084200</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5K1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10264" checksum="570A4BE4054DA075" modified="2022-10-12" version="1">MTTRTLHPCFILEKSLKPSYIVAKMTLEHLQSQGDFCLYTALPTVADDGDEGSIVHIAKSLAGSSVKNTQRPPTVEWSYAQNIASQPLQLASIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7R7</accession>
    <name>A0A8T0G7R7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G059900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7R7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="12"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0554069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="191" mass="21352" checksum="14303F3A812A759D" modified="2022-10-12" version="1">MVTSTSHRHLRYTVHNPGSEWGLCTCVWAQRGNMCKHHVKVVLMMHPEIAEGTIARYCGRLAGNVNGGLRQLLTPQRVQPPSFAEAETPYSPVKPSPVRPVSQDLPEMLSQQVNSLAAEVAGDTVLMEHLLAEFNLTLGRIRRLKAEIKSGVVHPMEGTPVFVPVDDGQGFKLARRRDFLEKPHKHVVRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8R8</accession>
    <name>A0A8T0G8R8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G079800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8R8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47988">
        <property type="entry name" value="SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="442"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="450"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="492" mass="52464" checksum="5B05CB57D0C260D5" modified="2022-10-12" version="1">MAGTKGGTLKLERLNPIHRTCAVMCIIGMSCSIWSVTVVTSQLMAPASPTTNPVDLQVLHEMMYAMYYEYDWATQVPDPCVSSPQGIICEADPVTGVLFVTQMQFGFISPIANIIPCSANASIPASIANLTRLTSLAFYSCFTNQTTTLPPELFLLGPSLRLLSFTQNPALSGPLPAGIAHLTGLQRMVLSQNSLHGTIPSELTTLPSLAQLDLSHNQFSGAIPPTFGAMDSLINLDLRYNALDGEFPVSLAQEAHNLQRLALSHNNLSGALPDTFTGLQSLTFLDLSSNELTGALPPSLGTLTHLEDLFLNNNRFNSAIPESITELKSLVRLDLSSCAFDGLIPSSLNHLESLRFFSVSNNRLSGPIPSSLASLPVLFTLNLDGNELTGPVPFPASFVQKMGRNLQLKENAGLCYSPQLVIIKLLLPGLKQCPESVLVPVTTTAPPPTSKDSPSPGSSQLPNGAPPAHPSDSSPARIFVAASILCFLSMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9Y5</accession>
    <name>A0A8T0G9Y5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G031500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="7917" checksum="D970A86290A6B401" modified="2022-10-12" version="1">MATSFTPTCPITQFGITFDFACSYHCCNLVDTTLHTRPNTPLGFTTTMSKSCCFAKSQAAFSARVFDSTYHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA28</accession>
    <name>A0A8T0GA28_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dehydroascorbate reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_11G016400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-dehydroascorbate + 2 glutathione = glutathione disulfide + L-ascorbate</text>
            <dbReference type="Rhea" id="RHEA:24424"/>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58539"/>
            <dbReference type="EC" id="1.8.5.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GST superfamily. DHAR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045174">
        <property type="term" value="F:glutathione dehydrogenase (ascorbate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033355">
        <property type="term" value="P:ascorbate glutathione cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000102">
        <property type="entry name" value="Glutathione S-transferase DHAR3 chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000029">
        <property type="entry name" value="Glutathione S-transferase DHAR3, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044627">
        <property type="entry name" value="DHAR1/2/3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44420">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE DHAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44420:SF2">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE DHAR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0216">Detoxification</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="7">
        <location>
            <begin position="98"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="8">
        <location>
            <begin position="154"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="32048" checksum="7E0407539679EF77" modified="2022-10-12" version="1">MRALTALSVCHSPSLSLLSASPRRKSNLPTLTSLANLANSVVYSVPDSGCAGVARGLKLGTGRLEGVTRRGVVAMADAGAADAAPAAPAPVEVFVKAAVGHPDKLGDCPFSQRVLLTLEHKGVPYDAKLIDTSNKPQWFLDANPEGKVPVMKDDGKFVADSDVITQILEEKFPEPSLKTPEDKANVGGKVFPKFVAFLKSKDANDGTEGELLTELKALDEHLKSNKPFIAGEKVTAADLALAPKLYHLKIALSHYKKWSVPEELTNLRSYIEAVHSLESFKKTQAEEDFVVAGWAKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAI4</accession>
    <name>A0A8T0GAI4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G190200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAI4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="11968" checksum="4A7A45FB9FD57C93" modified="2022-10-12" version="1">MPRAHARSSQGAHAYRGINVVNPTPPPLGTSPSTHVPEQCHGRHATVHPTPSVPELAPPSAGPRATHHATPSDAFAVQEARSIRQEESMTRCHPSHRGPRCITSTTAPGADEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB42</accession>
    <name>A0A8T0GB42_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ataxin-10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G048500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051374">
        <property type="entry name" value="Ataxin-10/CTR86_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019156">
        <property type="entry name" value="Ataxin-10_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13255:SF0">
        <property type="entry name" value="ATAXIN-10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09759">
        <property type="entry name" value="Atx10homo_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ataxin-10" evidence="3">
        <location>
            <begin position="421"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="535" mass="57739" checksum="2CA9BE1E912DD054" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCH3</accession>
    <name>A0A8T0GCH3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G022000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33133:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33133">
        <property type="entry name" value="OS08G0107100 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="340" mass="37370" checksum="59A02012338EAEDF" modified="2022-10-12" version="1">MVEGIPYGLGGWGVPSIFREAGRLLGKYFTFIAPFIFAFVLPTAVIQLLEVFGLAWWASGQDPPFLQKHRHVLSKAIAGVDGSYPATPAWESEFFILLGVGILMWLLASLAIASICKTVQYIYSEEEDPSATKSIFMSLPQAILRLLVTSIWILFLTLVTIFTVSLPFYLLSVIFKEKHEALFETVNQIFIYIAVTILSFLFLLSQEVAVLEPNNYGLAALKRSSKLVQANILPALAVFAVSLVVGGSLSKLSSYIASLHGAGKVPQWAVYILAILFALLYLTYVAYIYLATVVLYFSSKVKHDAAEGTLPGFRHGGSGNPYAPLVVVSHPILQNYHNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCV1</accession>
    <name>A0A8T0GCV1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G112400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="86"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0557236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="29662" checksum="41BFCB2409141FDC" modified="2022-10-12" version="1">MGCCQAKPGGISKADRAARWRSTGIVALRDSKIKELPVDVVDIASSVRTLDATHNKLGVLPEEIGNFINLQRLILAENLLERLPSTVGKLRSLKVLTLDSNRLSLLPEEVGLLQRLERLSVSRNNLNSLPSTLGNLSNLIQLDVSQNRLETLPESIGNCKSLEELIANDNLLQELPDSVSSLSHLKTLILSNQKLKQLPPLLLRNCTALQSLMLHGTLITSEQLHQMDGFEGYEERRKRKHDKQLDANVIIDSRGFDEGVDLHLAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEM0</accession>
    <name>A0A8T0GEM0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G150500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEM0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15863" checksum="BD9F809186C34F12" modified="2022-10-12" version="1">MLMTTACFVYTAHCIKLMLLIDLNASTCLLNNTQQSTSSAMVLNIFSEKNSPALTTKASSMLDRIQLIPEFMNTAHALQFSQARENSDHKHRYRISINDELNIAHPRKWSENNVEIKWKPISNRLVKFLEKATILLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEV2</accession>
    <name>A0A8T0GEV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Saccharopine dehydrogenase NADP binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G110300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43796">
        <property type="entry name" value="CARBOXYNORSPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43796:SF2">
        <property type="entry name" value="CARBOXYNORSPERMIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Saccharopine dehydrogenase NADP binding" evidence="1">
        <location>
            <begin position="59"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="470" mass="51387" checksum="08D66C41266A93C7" modified="2022-10-12" version="1">MAMATQLTRWWLASGPSHFELENWSARSNRQCFRRAGIRLVCQAKGSETVDEDGRKKRVLVMGGTGRVGGSTLRALSKGGDLHLIVGGRNREKGEALARELGGSVEFLGFDMDDPSALRAAVDGVDLVVHAAGPFQRRPECAVLEAAIDTKTPYIDVCDDQDYSVRAKAYHDKAVAAQIPAITTAGIYPGVSNIMAAELVRLNGNPKRIRYSYYTAGSGGAGPTILATSFLLLGEEAIVYVDGKIQKLKPYSARRDVDFGKGIGTKPVYLLNLPEVKSTHEVLKVPNVSARFGTYPQIWNIAMSLVASLVPKDILQDQQKVQGLVQWSDVAVRAVDGFAGERVAMRVDLECEDGKKAIGIFSHKMLSVTVGFSVAAFARAVLEGATQPGVWFPEEEGGIAESARRKLLERATEGTLNFVMNKYVLSCFQQNFNILWSLLLTKNCISAFHWNGKNHGSLEYYLINFEFSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHY6</accession>
    <name>A0A8T0GHY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G071400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="427" mass="47950" checksum="D9303718F57AC486" modified="2022-10-12" version="1">MNLSDFFLPSSLESRLVWNEQQEQRKLPVLRMPPHSAAKDVISASEEALEVMAPTMTDHLHVSRSHHVSTTTQLERVHSRELKDRREVLPRPSDITFYVGRNRAPFTISAHTLKHSVYFASLLEKQRIPDPVVLDCDEATFQNMVLILRYGSFEALPKMSESEAFRLKMELECYGIDVPAESQKPSSPSTSSSQAARTHSTSKNVHHRRAVYHPTSVVDFPDLPEELKDPSKVFLVARMDDIEKGVRCECMGKDLHTFWALSFHYRHTFCTGCGRCPSSLSPRHLAEMFMAAAMYYSQENSANKQRWSVGCDSTCSLKLLNAKPSCVCPCAVTDNCSESESPTLPAWAVSTYYSHAFCTRCGQAADERTLIFILLTLRYGGVSKHSKPRRDHAAGASSEGAIPQDSRIFASSPGSEILRHYRGTRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK40</accession>
    <name>A0A8T0GK40_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G138000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="11795" checksum="CC1219307FCD12E8" modified="2022-10-12" version="1">MQSGKGDEYKYKCPKHTIVVVSDKFSSLLKVGSSRKPVASVLFFSFAGLEALKLLGSEFETATQDFSEDPCCSTFVNDDVVNDLSSLSSALLGLIVNPLLCLSASSPLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN03</accession>
    <name>A0A8T0GN03_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CTLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G142900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN03"/>
    <dbReference type="OrthoDB" id="1602884at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048367">
        <property type="term" value="P:shoot system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000558">
        <property type="entry name" value="Topless-related protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000479">
        <property type="entry name" value="Topless-related protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027728">
        <property type="entry name" value="Topless_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048419">
        <property type="entry name" value="Topless_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054532">
        <property type="entry name" value="TPL_SMU1_LisH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44083:SF45">
        <property type="entry name" value="TOPLESS-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44083">
        <property type="entry name" value="TOPLESS-RELATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17814">
        <property type="entry name" value="LisH_TPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21359">
        <property type="entry name" value="zf_topless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00668">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="5">
        <location>
            <begin position="34"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="453"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="941"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="275"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="688"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1121"/>
            <end position="1158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="737"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1137"/>
            <end position="1158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1158" mass="126794" checksum="AAD0091E8994955A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNT3</accession>
    <name>A0A8T0GNT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_10G046300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.630:FF:000003">
        <property type="entry name" value="Cyclic nucleotide-gated ion channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000024">
        <property type="entry name" value="Cyclic nucleotide-gated ion channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45651:SF12">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45651">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="369"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="396"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="500"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0558682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="729" mass="83923" checksum="CF9CC81A85F72AD9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVA7</accession>
    <name>A0A8T0GVA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G133300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056894">
        <property type="entry name" value="AtTam38"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25114">
        <property type="entry name" value="AtTam38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="370" mass="38703" checksum="45ED45BB427EC84A" modified="2022-10-12" version="1">MASSAHLLHLKRPGALGLGFTLASPTQCASRARVRVGPIAAGRSGVGARLRHGLTGGGRVRRGAGLGLGLGGVAVAAAGRGDGEAGEVEVVAEEVDPNENSSFPAEFRELLVDRGDPPNLFLYAAGFCVVVLMRDVILQEIASWGLNFARIALYIGEYITIGLGQLTNVAATPVALLMNVVSWAIMAADDIYTLIVDGAPVRSLLSSLFLSLAVLSIGDAATSKVKGSRSRLVGIATAIGLAGVLEFIPPEAVIPSLVVLTAFAKFIQKADLVTVLMPATVSLVTISEPIIQAAALGIFLAVSIYASWRSAQQPEGQQSEQTPSQMREIKASSGMRPSFVFLAITASICISLGARFLYLRSVKWLLLRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW13</accession>
    <name>A0A8T0GW13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Auxin response factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_9G152000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimers and heterodimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009734">
        <property type="term" value="P:auxin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1040:FF:000001">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.330.10:FF:000001">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000047">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010525">
        <property type="entry name" value="ARF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044835">
        <property type="entry name" value="ARF_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31384">
        <property type="entry name" value="AUXIN RESPONSE FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31384:SF115">
        <property type="entry name" value="AUXIN RESPONSE FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06507">
        <property type="entry name" value="ARF_AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0927">Auxin signaling pathway</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="10">
        <location>
            <begin position="133"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="11">
        <location>
            <begin position="736"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="510"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="594"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="822"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="518"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="594"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="822"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0562509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="859" mass="94617" checksum="F4610BA98DE08238" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWH5</accession>
    <name>A0A8T0GWH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pectate lyase</fullName>
            <ecNumber evidence="3 8">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G050400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion. Required for its activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="3 8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018082">
        <property type="entry name" value="AmbAllergen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF187">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00807">
        <property type="entry name" value="AMBALLERGEN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035967659" description="Pectate lyase" evidence="8">
        <location>
            <begin position="28"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="10">
        <location>
            <begin position="326"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="85"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="604" mass="65787" checksum="3E794DE3CFDABD08" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXE4</accession>
    <name>A0A8T0GXE4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dirigent protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G110600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
            <location evidence="4">Extracellular space</location>
            <location evidence="4">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the plant dirigent protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXE4"/>
    <dbReference type="OrthoDB" id="1864232at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009699">
        <property type="term" value="P:phenylpropanoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.480.10">
        <property type="entry name" value="Allene oxide cyclase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044859">
        <property type="entry name" value="Allene_oxi_cyc_Dirigent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004265">
        <property type="entry name" value="Dirigent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21495">
        <property type="entry name" value="NUCLEOPORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03018">
        <property type="entry name" value="Dirigent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0052">Apoplast</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035962329" description="Dirigent protein" evidence="4">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="19827" checksum="B14ACB440EBFB87B" modified="2022-10-12" version="1">MAVSMKYSLAAVLLVVMISASHTHARLNPKHKTHNVTFYAHEAIETGDDATARIVAGPGGNISALQFGALVVVNNIITETADPNSLALGKLQGLYTLDGSKKYRAEVTIIIDQPGDLVETTYEVVGQRAGFNVTNERELAVLAGTGNYLGQKGYAVVSTVSQTLVPGSIIGAQYNIQKWTLVVGKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXE8</accession>
    <name>A0A8T0GXE8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_9G075500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="202"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0561582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="242" mass="27051" checksum="A360E1915C04B96D" modified="2022-10-12" version="1">MHRDIKAKNILLDRNYEAKIADFGLALLFSDGQTHITTDHVAGTKGYLAPEYALLGQMSDKVDVFSFGVLCLEVVSSRRNMDERLRPDMVYLVKWAWKLHGQGRLLDLVCPTLSLQDDEKPQVQRLINTALLCIQHTGEQKPSIARVVSMLQGDADLEVVVNPGAEDQYHQMDSARLLDLGNSAVSRVNDVSEEGPFWKSIRRDEGRRSSRTSESRSHRASEATVEGISSNGMITVSEIRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYP6</accession>
    <name>A0A8T0GYP6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PRA1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G073400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="12707" checksum="101B9C655CBA3815" modified="2022-10-12" version="1" fragment="single">IHYRDTLQLYHFSVGSLLVAITFLLGLVHPVAILIAAFIIILARITACSALKYFASTGQAQNRTGGCFNSGKHLRRMVFVVVNSRLIVQCITRSLHGGRHHHQHYEEDRCCPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZI1</accession>
    <name>A0A8T0GZI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G097600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="15320" checksum="2E15FA4480B0B879" modified="2022-10-12" version="1" fragment="single">VHVKITFSYLLPACPCRHASHLLLDFAACCRLGSTMRRATPSHAADRSVLPPSSSSRLLSAGLHRPRRLLYMHPITFGVITGSRVHPGFVHGWYEYADILHRLQCSYFSGHPRPRFESSTGRVTQLASHDAEESKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZN2</accession>
    <name>A0A8T0GZN2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G042300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZN2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000039">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF16">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 1 SUBFAMILY A POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12 13" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="467"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0563574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="530" mass="59668" checksum="7BE07CC83DC0A8E8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H118</accession>
    <name>A0A8T0H118_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2-carboxy-D-arabinitol-1-phosphatase</fullName>
            <ecNumber evidence="8">3.1.3.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G156800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-carboxy-D-arabinitol 1-phosphate + H2O = 2-carboxy-D-arabinitol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17837"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58008"/>
            <dbReference type="ChEBI" id="CHEBI:58185"/>
            <dbReference type="EC" id="3.1.3.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.63" evidence="8"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H118"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047538">
        <property type="term" value="F:2-carboxy-D-arabinitol-1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000018">
        <property type="entry name" value="Phosphoglycerate mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF10">
        <property type="entry name" value="2-CARBOXY-D-ARABINITOL-1-PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="9">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="119"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00052441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00066640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0565020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="571" mass="62001" checksum="DE72CB7276A2A270" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2Y0</accession>
    <name>A0A8T0H2Y0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G067100</name>
        <name evidence="1" type="ORF">KC19_8G131700</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2Y0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="199" mass="21788" checksum="79B89C5884C0504B" modified="2022-10-12" version="1">MAGEHAPLSNGRVVTFVGNGSVDFVDVENNGGVDVVVDTGNRENIPHVYAHSEDNVFHGRVEVWTRGVFREWLNSNHYYPVLEVEDFDIDVLGAEVLPAFFGTVLSSRGISFNIHALTNLYNSFDRMLRTFQIDHAIGLNRGVVRDGDAVRDGDAVAGEDGTVGRDRGAVIFSIRSDIRFANTRAAFMNAISGFPSGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4A4</accession>
    <name>A0A8T0H4A4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G084800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4A4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05476">
        <property type="entry name" value="pepsin_A_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034161">
        <property type="entry name" value="Pepsin-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051708">
        <property type="entry name" value="Plant_Aspart_Prot_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47967">
        <property type="entry name" value="OS07G0603500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274487" description="Peptidase A1 domain-containing protein" evidence="6">
        <location>
            <begin position="23"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="7">
        <location>
            <begin position="143"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="54282" checksum="D9F16E5996291FE9" modified="2022-10-12" version="1">MARAASLFSLSLLLCLMPLVAGYSISTLLETTVPLAGDGHSNGGASNGRELYYFSLKHRDAPNSPFLQRYSSRHELLQTVLQRDEERAKSFLEHIVQRRARQATGMVTEKGFVAMDSGSPPDPRSQQTGDAGVLLPPAGAGEYYTELYVGTPRQLQVAMVDLGSDVVWLGEAPSRLQKRRIDGDAVNSHFYPSSSSSFTPIPARSEPCLTVDGIHVCGNAKSCRVLVGTEDHYTGALEFAYEDIRLNRTHHHKGSVMANIMITISKTPIPTGGVLGLGLGKTSFATQMGSNHIANKFAYCLSDTDEPSGSSLVFNAGEDDPHLEFTPLVTHPHITTFHFVNLIAITVNNIKLPIPSKVLQLHNQGEGGTIIDMSTRFSRFPKSAFDHIMKAFKSHIDLPTILVPGFHLCYSMANSDILRVPSLTLVFQNNARMRLPMENLFVSASEQGDVMCLAMVPTSPGTPTVIGSTQQQNFLMVVDRGRSRVGFAPRQCASLPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4T2</accession>
    <name>A0A8T0H4T2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CCAAT-binding factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G098200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4T2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030692">
        <property type="term" value="C:Noc4p-Nop14p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027193">
        <property type="entry name" value="Noc4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12455:SF0">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCAAT-binding factor" evidence="3">
        <location>
            <begin position="356"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="610"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="104"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="675" mass="74677" checksum="7702580EE9E518F7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5I0</accession>
    <name>A0A8T0H5I0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial import receptor subunit TOM40-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G187900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Tom40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5I0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07305">
        <property type="entry name" value="Porin3_Tom40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="entry name" value="Porin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027246">
        <property type="entry name" value="Porin_Euk/Tom40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037930">
        <property type="entry name" value="Tom40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10802">
        <property type="entry name" value="MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01459">
        <property type="entry name" value="Porin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0565408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="345" mass="38500" checksum="2AEE2C5DE63BFD4F" modified="2022-10-12" version="1">MMGARGERESLHQEKGRERVCSGSVTMGAAISYCSPQEVLNTAICGDDGNGPDYMHLPCPAKYNEITREAYMSLKPELFEGLRFDITRPLNNKFALSNSLFMGSVGLPGNRQSKAHFELGADLVDQKGKMDIVLVMGRVLSDARMSARVKYDVNERFSIKADAQLTNDPHFTVGMFNFDYKGNDYQAQLTMGNNAYYGVNYMQSVTRTLSLGGEGIWLGRERKSNMGLAARFKTDTVCHNNGMQIATGLMKSEGLISCTYVQKLSDKISVASDFVYNWENGEAITSVAYDYLIRQCRLRGRIDTNLCTAAYLEEKFSSGLTFLLSAELDHRRKDYKFGFGMTIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8F2</accession>
    <name>A0A8T0H8F2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein MOR1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Protein GEM1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Protein MICROTUBULE ORGANIZATION 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G108600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TOG/XMAP215 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061863">
        <property type="term" value="F:microtubule plus end polymerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051010">
        <property type="term" value="F:microtubule plus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030951">
        <property type="term" value="P:establishment or maintenance of microtubule cytoskeleton polarity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007051">
        <property type="term" value="P:spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000019">
        <property type="entry name" value="Cytoskeleton-associated protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000121">
        <property type="entry name" value="Protein MOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000137">
        <property type="entry name" value="Protein MOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000155">
        <property type="entry name" value="Protein MOR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024395">
        <property type="entry name" value="CLASP_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045110">
        <property type="entry name" value="XMAP215"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048491">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12609">
        <property type="entry name" value="MICROTUBULE ASSOCIATED PROTEIN XMAP215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12348">
        <property type="entry name" value="CLASP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21041">
        <property type="entry name" value="XMAP215_CLASP_TOG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="12">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="12">
        <location>
            <begin position="274"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="10">
        <location>
            <begin position="446"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="12">
        <location>
            <begin position="589"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="12">
        <location>
            <begin position="843"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="12">
        <location>
            <begin position="1173"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="548"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1074"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1424"/>
            <end position="1462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1863"/>
            <end position="1929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1948"/>
            <end position="1979"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1074"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1438"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1948"/>
            <end position="1975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00079374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00082866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0567085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2005" mass="218406" checksum="6BEB5889706B2540" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB73</accession>
    <name>A0A8T0HB73_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Legume lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G059800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB73"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035741528" description="Legume lectin domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8669" checksum="213FB98ACFBA4DDA" modified="2022-10-12" version="1">MFSILFVDSMIFFSILNSTLGLAGETIRSTWTLVFSKTNTIYNNDEGNVSSFKGIRHSEFSTTLLVQGNEGYFAWKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCH3</accession>
    <name>A0A8T0HCH3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G097000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035929909" evidence="1">
        <location>
            <begin position="19"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6513" checksum="49485C2B589C236E" modified="2022-10-12" version="1">MPFLQFMVMKLQTILVLSIDVSFTGSNALCGYAVRSPPISHFFHGDPLQKLFNRLIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCM4</accession>
    <name>A0A8T0HCM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Vesicle-fusing ATPase</fullName>
            <ecNumber evidence="6">3.6.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G091200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.6" evidence="6"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043001">
        <property type="term" value="P:Golgi to plasma membrane protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035494">
        <property type="term" value="P:SNARE complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000115">
        <property type="entry name" value="N-ethylmaleimide-sensitive fusion protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000166">
        <property type="entry name" value="vesicle-fusing ATPase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000187">
        <property type="entry name" value="Vesicular-fusion ATPase SEC18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039812">
        <property type="entry name" value="Vesicle-fus_ATPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078:SF3">
        <property type="entry name" value="VESICLE-FUSING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23078">
        <property type="entry name" value="VESICULAR-FUSION PROTEIN NSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="228"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="7">
        <location>
            <begin position="507"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="731" mass="80858" checksum="E97E6603BFC71D5D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDI0</accession>
    <name>A0A8T0HDI0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G120300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="24618" checksum="90DA107BC249F1F9" modified="2022-10-12" version="1">MHHSFSFLTNYFLKVSPKTEQNHINRNYSHIIRTYTKGTWLKNKNHTLRLQTSQTRNKSSLQVQLQFQLHLPHSTWRWNSTQWDGISECLIRCMRSYRECEDLMEIASMVRIGVRRNETDERKLRPYMCEFLYEKARMYCMLPDGIMRHEEKRCDDRVQLHERRNVVIVGPTVHIQAASQHQQQQELNKQQPTALCYVMLCYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEA5</accession>
    <name>A0A8T0HEA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G045000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12450">
        <property type="entry name" value="RRM1_NUCLs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12451">
        <property type="entry name" value="RRM2_NUCLs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034349">
        <property type="entry name" value="NUCL_RRM1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034350">
        <property type="entry name" value="NUCL_RRM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23236:SF119">
        <property type="entry name" value="NUCLEAR RNA-BINDING PROTEIN SART-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="147"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="245"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="222"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="308"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="9"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="350"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="402" mass="41684" checksum="235E9CE1253A1699" modified="2022-10-12" version="1">MGKSKKKSQAVAAVVPAAVPEEKKTAKRAVEAAAGVPPTKKSKGQKKVVPPPKKVESSEEESEEEAAEEESSDEEMLPAAKAVNGKAANGKGANGAAADSDEDEEDDSEEDEPVKKTGAKPAESDEESEEEVQVKTPAKQASEGGSKTIFIKNLAWAADQDVVSEFFSDCGTVTDVRIAQDENGRSRGFGHVEFESEEAAKKAVEKSGQNLEGRDIFCDLARERGAGPGGATPNGATPGRTGSDKTAYVRGFDKYQDEDSIRSGLTEFFGECGEVLNVRIPTDRESGEIKGFAYVEFASKDELTKATEMDGSDFNGRSLVVNEASSGGTPGGRGGGRGGFGGRGGDRGGRGGGRGFGGRGGRGGDRGRGGRGGGRGRGDFGGRGGRGGRSSAPAGKKMRFDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF44</accession>
    <name>A0A8T0HF44_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G100900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043489">
        <property type="term" value="P:RNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838">
        <property type="entry name" value="NUCLEOLAR PROTEIN OF 40 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838:SF3">
        <property type="entry name" value="PROTEIN PIGMENT DEFECTIVE 338, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="357"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="441"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="584" mass="63941" checksum="EB476995CCEBD1A5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFC0</accession>
    <name>A0A8T0HFC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G052800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="15793" checksum="4F12FB75E9DF4D1C" modified="2022-10-12" version="1">MSNNESQYLSNKYRDEWKDRDQITEDQIEHFIQQYLGELKDGTWKSGGWQHMYTGYSNTKVALNAYTSVLAREVGPETEKVYVNCFNPGFTKTNLNDYQGHNTLEEAAMTGIWLALHPPGGPHGKYLEQQNWGITAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGA3</accession>
    <name>A0A8T0HGA3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G131800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035767427" evidence="1">
        <location>
            <begin position="16"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6574" checksum="0D091C1824FB2CE0" modified="2022-10-12" version="1">MALASIYINLHIILARIFSTCCHMYKSPSNRPHSIASTIAHLHAHINVDHHKFNIAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGZ8</accession>
    <name>A0A8T0HGZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SAYSvFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G129500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039159">
        <property type="entry name" value="SAYSD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019387">
        <property type="entry name" value="SAYSvFN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13527">
        <property type="entry name" value="SAYSVFN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13527:SF0">
        <property type="entry name" value="SAYSVFN DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10260">
        <property type="entry name" value="SAYSvFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="SAYSvFN" evidence="2">
        <location>
            <begin position="95"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="166" mass="19290" checksum="A70876D1A0880C06" modified="2022-10-12" version="1">MVLQRFKLPESATPLQRQVATFLRSKLKVPGIAANRLYVHTVNQHCMFLNMIRYWQFGYLYFASTFFLTNLMSSMGADVALIVLFSISLRTWLLTILWFVLLPLARRWDLGPLYIITTIFLVIFMNLGKRQPGEASAYSIFNEDFRELPGTLNAERLDRDIRAGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIL3</accession>
    <name>A0A8T0HIL3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G173100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8723" checksum="6E4A3360244CE303" modified="2022-10-12" version="1">MHRVSNIGPQSGFVDDRLVEDDEYQLKVGRAGRIFPGEEKFLILLEPRRFIIYERTPTSDCFNGVYNGNVLLYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKL7</accession>
    <name>A0A8T0HKL7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG004800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="10201" checksum="DE2577419928F1C7" modified="2022-10-12" version="1">MDTLMLRRRIRNRRFTQDCLREKLYHLVDTTEIISSTISSPEVKTCNCCPRIKTFTSTATQEIQAWKEVNYHTLLQMLMTLFSRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLR3</accession>
    <name>A0A8T0HLR3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG037000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="9677" checksum="54122A8CF6E2359F" modified="2022-10-12" version="1">MYTRILCPRSARCWFECNPRTYLNSQWYPPPCRSILVVEYDNAPHLTCGRFLRCHDLQPYPPLQHCQFPKSLLHFFSTTDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN28</accession>
    <name>A0A8T0HN28_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG077200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="10889" checksum="E5F62C143D93CAD3" modified="2022-10-12" version="1">MGFSSEGYVASSSYGRFTAGSVLKIWWISTVEDHGYSFSDDISNIYGSKARCYSNGWLSDMLASMACTILASMACSILASMACSIKYGPYVLSQSSTLLGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN45</accession>
    <name>A0A8T0HN45_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG079000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035932663" description="Secreted protein" evidence="1">
        <location>
            <begin position="16"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9616" checksum="0E773E7C21E11BE4" modified="2022-10-12" version="1">MFFVLLASETMLIRAGLTYGLMRSESVALRTGCSLELSMHVVCTPHRSVEAFFHTRNMEFFGEVDTLPSQIRNQSTVYSFYDQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNM2</accession>
    <name>A0A8T0HNM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG091800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46880:SF5">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46880">
        <property type="entry name" value="RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035794321" evidence="1">
        <location>
            <begin position="25"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="253" mass="29115" checksum="8E3706CA628D48B7" modified="2022-10-12" version="1">MYQHLLMCIALHIDALAAIDATEASPELRVLDDFSNFAKKWVGRSSLRRTELNQLMVEFAIDPLVVLHIHGVRWLSRGQVMQRVLDCMPLFLELFREEEEMWYHKLTSFQFQFLLRLLVDILIELNKLNKLFQNDHVDITQIGGHLNICINILSRRFLPARGAAFGRGSKALWPFLETCSTSMEIEYPIADGGMRTYPMHLESVTGRAGTIEECKLIRAEYVQRVVDALNNRFPDLGISKLRLALQPQSLSCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQM7</accession>
    <name>A0A8T0HQM7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG130700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16546" checksum="527AAF7689005031" modified="2022-10-12" version="1">MPDHDKVKVLDYEGWPSSWNRKALIQFQTVAHGTGIMHPPQEERARPSVAKNQSVLRPVLALPTLPKINTNVPIMRLVLAVPALHKIDLNGPVRAKCGRNAEFGQSTSAFAIQSPQLPRPPPMELVDLSDSSEKTCHEDSPSEGSVSIKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSD3</accession>
    <name>A0A8T0HSD3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG180000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035734068" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9079" checksum="CFCE5550C4C12337" modified="2022-10-12" version="1">MAVLLSSLLRILVGKMFVIHMKSIYHTLCEVKVFLTRIQARRRGVRSIGSNSVLFPFNVGVVRALICRSFLDLVYIPSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTM4</accession>
    <name>A0A8T0HTM4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG259200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16847" checksum="B97E0CDB707055E9" modified="2022-10-12" version="1">MDPGWQTKVVFGKDIVRCTISLPSVTFRYHVGRSVLYSNFKYGRERLAQDGVTWELIDQVREEDMVVLPCFFQGLPVARFEVGRGWPLSHIRREVAITLGDVAPEDLRFVLKRVGYPDVKVNRRHEGSNTVSQVLPPWTFEIVALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUF5</accession>
    <name>A0A8T0HUF5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG239600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15217" checksum="905BDB21DE77C8C3" modified="2022-10-12" version="1">MDGRNSSVRRTSGRGSSLYSTPGGYGVPPANTPEFTKTLRLSHTSPHYSAKLVSHPLSKSFPKLLVCTELTPNIHATGAPSASSLLETLAPVYVIHRNSHRGQPFCYFTHGWALFRDENFFKVGYTLVSPVHFQVIQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVE8</accession>
    <name>A0A8T0HVE8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator of RNA polymerase II transcription subunit 31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_VG282800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the Mediator complex subunit 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1340:FF:000001">
        <property type="entry name" value="Mediator of RNA polymerase II transcription subunit 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1340">
        <property type="entry name" value="Mediator of RNA polymerase II, submodule Med31 (Soh1)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038089">
        <property type="entry name" value="Med31_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008831">
        <property type="entry name" value="Mediator_Med31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13186">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05669">
        <property type="entry name" value="Med31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0010">Activator</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="141"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0574681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="21660" checksum="950B11AEA961B894" modified="2022-10-12" version="1">MVGNGDAGGGYESQPLLGHQPSSPPWHQKFQDPDDGRQRFLLELEFVQLLANPTYIHHLAQNRYFDDEAFVGYLKYLLYWKQPEYAKYIMYPHAFFFLDMLQSANFRAAMAHPANKEIAHRQQYYFWKHYRNNRLKQILPRPLPEPEVPAPPAPPPAPVPVVAVAPTKPEGSTRAGAGERRKRKYANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWK0</accession>
    <name>A0A8T0HWK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG315500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="207" mass="22607" checksum="5BE6AAD34935100E" modified="2022-10-12" version="1" fragment="single">VVGYRNLPYAGQDTNAAIEGYHGFLKDFAVSAIVKARLIPDSDVSLNQSPGNCALNPGEEWTGCSCAWAARGNICKHMVKDLLMIRPDVAEGTIARFCGRQVGNVQGGMRHVLDPTTLKDVANTLRQLVVYLSQDVAGDPVLMDHLVAELNQVVGRIRSLKAEIRTGTVHPLVDSPVLRTVNDGRGFSLVRDMDFLERGGKRVSRRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWS4</accession>
    <name>A0A8T0HWS4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG323800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWS4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="7946" checksum="65C5A2EB175DC564" modified="2022-10-12" version="1" fragment="single">SDEPSHYSGRFNAQVHIVACTGGRALEPFGPVNTTWSNVKMLSSSAADAHLSCFTCDHRAQAPWTLQDEHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXB1</accession>
    <name>A0A8T0HXB1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HhH-GPD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G029100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkylbase DNA glycosidase AlkA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXB1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032993">
        <property type="term" value="C:protein-DNA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032131">
        <property type="term" value="F:alkylated DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006285">
        <property type="term" value="P:base-excision repair, AP site formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.340.30:FF:000004">
        <property type="entry name" value="DNA-3-methyladenine glycosylase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.340.30">
        <property type="entry name" value="Hypothetical protein, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051912">
        <property type="entry name" value="Alkylbase_DNA_Glycosylase/TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43003:SF5">
        <property type="entry name" value="DNA-3-METHYLADENINE GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="DNA-glycosylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH-GPD" evidence="5">
        <location>
            <begin position="189"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="50"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="54"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0575762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="350" mass="36902" checksum="22B576EC0CD53425" modified="2022-10-12" version="1">MAGLEAMKVSGAMLNGEVVGRVLRSRSAKVVQANVAKLVDSKITFKAKKGAKAAVEKEKPSGKREAGAATSVAGSGGAGAVEQGKKPRKSSEKTIVVTETISTEVATEGADQGVGASGEGSSVVGKVTVSSSTTESWGISLSTAGAVAEATKHLIAADTKLAKIIGSHGSSPVWEQTGSCFTALTRSIVYQQLAGKAAAAIYGRLIALCGGPESLTPARITALTDEELRAVGISGRKATYLHDLAEKFTSGFLADEKLMVMNEDDLVTALTAVKGIGVWSAHMFMIFYLHKPDVLPVGDLAIRKGFQKLFDLKQQPTPAEMQELALSWRPYRTLASWYLWRMADIKMPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXP0</accession>
    <name>A0A8T0HXP0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G038200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="13726" checksum="685A9FB0A17CB03B" modified="2022-10-12" version="1">MSYQCSYSWNYILAFGNCVSFCMLYEILHQLEFSWKFVGMMAGMWPSNQSTRSSSAIAVLKNNVEYLREELQRCLRYSFFNLREDNPRIGENFPELWYSTFSNVVERLFYLRNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY35</accession>
    <name>A0A8T0HY35_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G049800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030332">
        <property type="term" value="F:cyclin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000082">
        <property type="term" value="P:G1/S transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010389">
        <property type="term" value="P:regulation of G2/M transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000281">
        <property type="entry name" value="Cyclin-dependent kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000231">
        <property type="entry name" value="Cyclin-dependent kinase B2,2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF254">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="8"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0576034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="307" mass="34935" checksum="53709611981BCC6E" modified="2022-10-12" version="1">MFSGMDNYEKLEKVGEGTYGKVYKARDKRSGQLVALKKTRLEMEEEGVPSTALREVSLLQMLSHSMYIVRLLCVEHVEKNKKPMLYLVFEYMDTDLKKYIDLHGRGPSGKPLPVKVVQSFMYQLCTGLAHCHGHGVMHRDLKPQNLLVDKQTRRLKIADLGLGRAFTVPMKSYTHEIVTLWYRAPEVLLGATHYSLPVDMWSVGCIFAELVRKMPLFTGDSELQQLLHIFRLLGTPNETIWPGVSQHRDWHEFPQWRPQDLSLAVPGLSAVGLDLLAKMLVFEPSKRISAKAALSHPYFADLDKTAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYK7</accession>
    <name>A0A8T0HYK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">16S rRNA (cytosine(967)-C(5))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.176</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">16S rRNA m5C967 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">rRNA (cytosine-C(5)-)-methyltransferase RsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_5G043500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>cytidine(967) in 16S rRNA + S-adenosyl-L-methionine = 5-methylcytidine(967) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:42748"/>
            <dbReference type="Rhea" id="RHEA-COMP:10219"/>
            <dbReference type="Rhea" id="RHEA-COMP:10220"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74483"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.176"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.176" evidence="3"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000022">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="entry name" value="NusB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049560">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB-F_NOP2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023268">
        <property type="entry name" value="RCMT_RsmB-rel_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004573">
        <property type="entry name" value="rRNA_ssu_MeTfrase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054728">
        <property type="entry name" value="RsmB-like_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011494">
        <property type="entry name" value="PRK14902.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00563">
        <property type="entry name" value="rsmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807:SF61">
        <property type="entry name" value="NOL1_NOP2_SUN FAMILY PROTEIN _ ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22458">
        <property type="entry name" value="RsmF-B_ferredox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02009">
        <property type="entry name" value="RCMTFMUVIRPL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="NusB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="8 13" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM-dependent MTase RsmB/NOP-type" evidence="15">
        <location>
            <begin position="316"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="13">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="408"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0575956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="600" mass="65728" checksum="38382F0E0F34782D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ02</accession>
    <name>A0A8T0HZ02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GDSL esterase/lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G021500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01837">
        <property type="entry name" value="SGNH_plant_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035669">
        <property type="entry name" value="SGNH_plant_lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22835:SF648">
        <property type="entry name" value="GDSL-LIKE LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22835">
        <property type="entry name" value="ZINC FINGER FYVE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035893785" description="GDSL esterase/lipase" evidence="4">
        <location>
            <begin position="34"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0575663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="403" mass="44231" checksum="4C1F84299917B394" modified="2022-10-12" version="1">MAFGGMAVGMAVSGVGAAAVLLLVLGSVGLSAAELQNCSFSALYSFGDSLTDNGNAIAALPEQFIDSEENPNGVNFPHHAADRYCDGRLLVDYISFGVRLKPNYAILRSIAADFAYGANFAFAGATARNNTEWRQMSGFNSPFSLNIQVSWLERYKVRLEFYYEQIAVNQTLPAVDSLNTSLYFVNAGFQDYFFPLYYKEITAKEALELVDSVVGAIITAVKRIFAFGARTFMIVNLPPLGCLPALLTLYPEVDSARYDTYGCLDVFNNISKTHNALLLSRVEDLRSTYTNATFYLADYYNVYRDVLKSPADYGISGTLTACCGYGGSYNFNQSLFCTHSGVVNGSDIELIYPCLNSTAYLNWDGIHPTAQMNWIAATAFFNGTHITPIGGFNCSADYSNWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I169</accession>
    <name>A0A8T0I169_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G114100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I169"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="19729" checksum="6B026FC1284919FA" modified="2022-10-12" version="1">MAAYLPEVYMPPEPLMVINDRRRLIGRPLDPYYGPTTQDFGPYTRSRLVPDVTMRAPIFTLGDIARIKDALALEGVYNVICDIPEQTVIVSTRLSPTSIVSLVRQVMGDATLISVVDPYPVSSAAVMPRTRYAYDDMYSYPSSSGYGYGYDPYNGRSYDNEFRPSRYYTGYSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1I3</accession>
    <name>A0A8T0I1I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Raptor N-terminal CASPase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G145800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat RAPTOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030674">
        <property type="term" value="F:protein-macromolecule adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071230">
        <property type="term" value="P:cellular response to amino acid stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030307">
        <property type="term" value="P:positive regulation of cell growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000145">
        <property type="entry name" value="Regulatory-associated protein of TOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004083">
        <property type="entry name" value="Raptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029347">
        <property type="entry name" value="Raptor_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12848:SF16">
        <property type="entry name" value="REGULATORY-ASSOCIATED PROTEIN OF MTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14538">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01547">
        <property type="entry name" value="YEAST176DUF"/>
    </dbReference>
    <dbReference type="SMART" id="SM01302">
        <property type="entry name" value="Raptor_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Raptor N-terminal CASPase-like" evidence="5">
        <location>
            <begin position="88"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="749"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="873"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="913"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="766"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="782"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1394" mass="151590" checksum="1223A2301D03ED6D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1K4</accession>
    <name>A0A8T0I1K4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G101100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1K4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF82">
        <property type="entry name" value="OS08G0230500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="381"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="603"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="449"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="678" mass="75167" checksum="694A55E5E6743EA3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1S8</accession>
    <name>A0A8T0I1S8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G153400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WEB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1S8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008545">
        <property type="entry name" value="Web"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32054">
        <property type="entry name" value="HEAVY CHAIN, PUTATIVE, EXPRESSED-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32054:SF31">
        <property type="entry name" value="PROTEIN WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05701">
        <property type="entry name" value="WEMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="102"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="192"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="309"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="362"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="505"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="889"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1025"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1112"/>
            <end position="1129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1174" mass="128545" checksum="FC3A07BD3A602B21" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I358</accession>
    <name>A0A8T0I358_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G157600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I358"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000042">
        <property type="entry name" value="probable strigolactone esterase DAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43039">
        <property type="entry name" value="ESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="29969" checksum="D57690E61AD2E9D1" modified="2022-10-12" version="1">MAELPTLLELHNVRVIGMGEEIVVLAHGFGTDQSVWQHFIPHLLDDYRMILFDNMGAGTTDPEYFSFSRYSTLHGYADDLLSILEELEVQSCIYVGHSVAGMVGCLASLERPELFTKIITISASPKYLNDMDYFGGFEQEDLNQLFAAMQSNYKAWVSGFAPLAVGADIESQAVQEFSRTLFNVRPDIAFSVAKTIFQSDLRSMLPNVTVPCHILQSNKDLAVPVVVADYLHHTLGGPTIVEVLQTEGHLPQLSSPDVVIPVLKRHIAGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3D8</accession>
    <name>A0A8T0I3D8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G196800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3D8"/>
    <dbReference type="OrthoDB" id="437960at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.110.10:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 4-phosphate 5-kinase 8"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.110.10">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003409">
        <property type="entry name" value="MORN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084:SF179">
        <property type="entry name" value="OS10G0565000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23084">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02493">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00698">
        <property type="entry name" value="MORN"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82185">
        <property type="entry name" value="Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="455" mass="50622" checksum="C546AF48B5B8D8C1" modified="2022-10-12" version="1">MELSKLSKSPSLLRSPTIKSGINSLTSLDELERSHEQAIKTRGCCWPQTSGSRDGRTSGDGYAYLRERLQLLVPPSIIVSVPFVWWCVKAGPSYGVQWLSLDIVPWYWFNVSALLVLFVAVIVSVHLAGPHLFGRALVSPAWVVVRDTCGQSWNFVHSSCLLPLGAILQQLSDKKENEWKVRAQSQGTRSPGKLTKPKKNQAYGEGVQTFSNGDVYEGEFYRGKFSGSGVYYFYKSGRYEGDWVDGKYDGHGVETWARGSRYRGQYRQGMREGYGIYRFYTGDVYSGHWSNGQSNGCGMQTCGDGSCYVGEFKWGVKHGFGHYQFRNGDTYAGEYFADKMHGYGVYKFANGHRYEGSWHDGRKQGLGIYTFRNGDTHAGHWHLGTLESRSTQVPNASAPVAVSHSKVLNAVQEAKKAAQRGMDVERVDDRVKKAVALANQAANAGRVAAVKALHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4H7</accession>
    <name>A0A8T0I4H7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G020000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4H7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="18267" checksum="83479BDF89EA45FD" modified="2022-10-12" version="1">MPATHSKLTFRNETEEDIVFIHIFKNVQGNTFTVRSRGGLHVENVTVCQTHERFCLLGSDGKKITGKEFDTDDLPDFTGVVVTKVGDEYILTKVRRTTWWTWLQSQIHRIPKLFSQDETLPTRWKVQQAPFVVKLACVFAGRPALEDGLCRKSIYSPRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I525</accession>
    <name>A0A8T0I525_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G165000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I525"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035924309" evidence="1">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="7692" checksum="FB83DF3A96994418" modified="2022-10-12" version="1">MLRVTLAKLLFLIQKSLPCTNCKNLLQRSTQWKNKTTRINRIKHLSYTLQAIVKASLFCCYFTKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5E3</accession>
    <name>A0A8T0I5E3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_4G042100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11 14">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 14">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="11 14">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="14"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5E3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31388:SF5">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31388">
        <property type="entry name" value="PEROXIDASE 72-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="7 11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="56"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="83"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="136"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0578682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="345" mass="37045" checksum="E55B56B06048A726" modified="2022-10-12" version="1">MSGVNTWNVQVVDRTYLIVPLSMAKTSSRRSLYGILWSTLTVDDGRRSVSQDPALYMKQEVQTAVANERRMAASLVRLHFHDCFVNGCDGSVLLDNSTDFETEKDAAANINSARGFEVIDTIKAAVEAACPNTVSCADILAITSRDCAVEVGLTSNYAVLLGRRDSLTASKAQANISLPAPNLNFSGLVQNFAAVGLDETDLVALSGAHTIGRANCSLLLLFALNNVDINPDFNSTVFQECLANTSSLQNLDLTTPDDFDNNYYGNLLNSEGLLISDQTLFSTPGAASVAVVQNFASNQDAFFSQFALSTINMGNIKPLTGDQGEIRTNCRVVNSASPAQLIAYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6G2</accession>
    <name>A0A8T0I6G2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G034300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6G2"/>
    <dbReference type="OrthoDB" id="10264062at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000025">
        <property type="entry name" value="TBC1 domain family member 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF689">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 15-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="1">
        <location>
            <begin position="56"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="429" mass="48999" checksum="6C8BE417A4F24237" modified="2022-10-12" version="1">MGDDPYALRPDCTDSAPPRFRIKAGKTLSPRAWYAAFNDQGQLKLDRVLKRIRRGGVDPSIRAEVWEFLLGCFVPSSTAQERDAIRASRREQYAKLKSECRGMDDLIGSGQIATAPRVNEDGSPVEEYHGGEISGADDIRQHQNGYTNGVHPVTSKPPFIKQDEKAIQWRLNLHQIGLDVVRTDRMLQFYASQQHMSKLWDILAVYCWLDPAIGYCQGMSDFCSPLALMFSDEADAFWCFERIMSRVRDNFSCTDKEVGVQKQLGVLATLLKVLDPKLHQHIDSIGGGNYIFAFRMIMVLFRREFSFVDTLYLWEMMWSLEYAPQSIQEVSATRSWSLRRKYKGRGKYEAQNEKYGASRIPCGNAPLSLFCAVAIFEMQRSRLLKETQGLDEVLKLLNDITGKVDPKQACKAALKLHSKYLRRVRRATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7P1</accession>
    <name>A0A8T0I7P1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G073600</name>
        <name evidence="3" type="ORF">KC19_4G087000</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7P1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13121" checksum="F3AED0F135B75DF0" modified="2022-10-12" version="1">MYLEGQWLQTLVRMTEEQFLKLSRGEQIKMLTAFRIKGTFWLTPMAILNGFEEDMDTSNFSSLDMPTSSAGRPLSCTQDSVPGIDMEGDGGTPCTQRYKRKLDNDNVGASSNKVKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7V7</accession>
    <name>A0A8T0I7V7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G078200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7V7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805569" evidence="2">
        <location>
            <begin position="20"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10861" checksum="7E17F22B9091D552" modified="2022-10-12" version="1">MLCFFYLFILVALVCVMLCEEDRDGSVVTPGCGSSSCVSAVDVLLMWPGFMGLHELLYGFMGVVLSGASKGARLVSMKLEVENMIPLMNKGVLNYVCIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I981</accession>
    <name>A0A8T0I981_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system transcriptional repressor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G089200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I981"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050990">
        <property type="entry name" value="UPF0237/GcvR_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34875">
        <property type="entry name" value="UPF0237 PROTEIN MJ1558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34875:SF6">
        <property type="entry name" value="UPF0237 PROTEIN MJ1558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13740">
        <property type="entry name" value="ACT_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="231" mass="25019" checksum="C081156A76ECEF7F" modified="2022-10-12" version="1">MMQRAGAKLPELWRCGSSSLLRHLPLCTLPDPQEETHSGVQGLVVTALGPDRPGIVAGLSKRVLDCGGNFEISRMSRLAGEFSISLLVTFDVTTTRKAEQLCSSLQQIEGLQVNTRWISDDRLKQTRPLQKYGKILLRGVDNPGLVYNLSEYLSSHGINIESLETHTQEAPSGSGTLFMMEGVIAMPVGLSTATFLHNLNTLQATLGAEISISDLPSPVQKFAPSCPQESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAN1</accession>
    <name>A0A8T0IAN1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Presenilin</fullName>
            <ecNumber evidence="10">3.4.23.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_4G199500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer. Probable component of the gamma-secretase complex, a complex composed of a presenilin homodimer, nicastrin, APH1 and PEN2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Golgi apparatus membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="10">The PAL motif is required for normal active site conformation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase A22A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.-" evidence="10"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070765">
        <property type="term" value="C:gamma-secretase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005798">
        <property type="term" value="C:Golgi-associated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006509">
        <property type="term" value="P:membrane protein ectodomain proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016485">
        <property type="term" value="P:protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.100:FF:000002">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.100">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001108">
        <property type="entry name" value="Peptidase_A22A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042524">
        <property type="entry name" value="Presenilin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202">
        <property type="entry name" value="PRESENILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10202:SF13">
        <property type="entry name" value="PRESENILIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01080">
        <property type="entry name" value="Presenilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01072">
        <property type="entry name" value="PRESENILIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="10" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="439"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="227"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="339"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="251"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0580790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="472" mass="51199" checksum="C56F6187118FA3AF" modified="2022-10-12" version="1">MEKGILDVVGGEIISLVTPVSICMFLVVSMVHILDPHGEDKPISSIAMMAYNEQASDSFSEKLGGALLNAIVFVLIVTVVTFMLVALFYYRCTRCLKVYMGMSAFTVLAWMGGIVAVQFIRLYSIPVDVVTFLICTINFASVGVAAVFFTRMPILVTQGYLVVIGALVAFWFTKLPEWTTWILLLAMAGYDVVAVLTPRGPLNLLVEMAIERDEEIPALIYEARPNYPSGVQMPPPSSDAQTTRVRRWRRNSQASNARPDTELGESSRSASNAHPETTLISSEGDSQILVPAVPEVGILGSRLISPVGEAGSLNAVSTVMHENQVSDSHLDDDTAPLVQRHAQSSASTGISDRVEAEADDRSRRLHGTSQPAEEDNEEPGIGTSGGLKLGLGDFVFYSVLVGRAAMYDLMTVYACYLAIVAGLGATLILLAVWQRALPALPISISFGVLFYFLARLFLDPFVLDMSTSLVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB48</accession>
    <name>A0A8T0IB48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G153000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB48"/>
    <dbReference type="OrthoDB" id="1518325at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008889">
        <property type="entry name" value="VQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039607">
        <property type="entry name" value="VQ_8/17/18/20/21/25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33143">
        <property type="entry name" value="F16F4.1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33143:SF6">
        <property type="entry name" value="OS08G0102900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05678">
        <property type="entry name" value="VQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VQ" evidence="2">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="15707" checksum="0AB0BEC59D2470B9" modified="2022-10-12" version="1">MGAIEAHVNASKPTPLKSTGLQLNKSGPVITKPRVIHTYSPRVYKIQPEEFLELVQKLTGKTVAQPKRLTTIQFFETDSFKTGSKSGNSRSQETPVASSNVGDFANSGEALASPYTRNLLGALPSPRLVTLNFLPLLTTPRAQTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC71</accession>
    <name>A0A8T0IC71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G244000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11851" checksum="78DFC9E74CF7DC69" modified="2022-10-12" version="1">MILRLLFQNLSSFVKHKEMQPKDEPPTKFPELLPKYNVELLMPTLLQHMKHTALNETHLVCRVADPHITSPHCKFLYHLLIPTLIQHGKHQAVNPMGLHMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFG5</accession>
    <name>A0A8T0IFG5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G238300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Vesicle trafficking protein that functions in the secretory pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus</location>
            <location evidence="8">trans-Golgi network membrane</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Prevacuolar compartment membrane</location>
            <topology evidence="10">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031090">
        <property type="term" value="C:organelle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000030">
        <property type="entry name" value="syntaxin-51 isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF285">
        <property type="entry name" value="SYNTAXIN-51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="199"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="13">
        <location>
            <begin position="127"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00054128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00060376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0581268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="220" mass="24729" checksum="8319227280D6D78E" modified="2022-10-12" version="1">MADSWTREFQEAARLAEDVEGRIAEKDGLPPHSSESIQIVSVSRRKLAMLNNKVDRLESLLQSGLNEKELSRRQNMLVDIRYKSKQMSAALSSAQANRASLMERGIAPVEISQTQGLDNSGLVNLQMQIMKEQDQDLEDLEHTVLSTRHIALAVNDELDLHTRLLDDMGQSADVTNNKLLAAQRRLGFLNKNPGQGWSLLRMIFLMVVVVILVLVLFKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG25</accession>
    <name>A0A8T0IG25_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">dihydropyrimidinase</fullName>
            <ecNumber evidence="8">3.5.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G014200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16121"/>
            <dbReference type="ChEBI" id="CHEBI:11892"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15901"/>
            <dbReference type="EC" id="3.5.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Carbamylation allows a single lysine to coordinate two divalent metal cations.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.2" evidence="8"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004157">
        <property type="term" value="F:dihydropyrimidinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006208">
        <property type="term" value="P:pyrimidine nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000001">
        <property type="entry name" value="Dihydropyrimidinase like 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="entry name" value="Urease, subunit C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050378">
        <property type="entry name" value="Metallo-dep_Hydrolases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647:SF1">
        <property type="entry name" value="COLLAPSIN RESPONSE MEDIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11647">
        <property type="entry name" value="HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="Composite domain of metallo-dependent hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274574" description="dihydropyrimidinase" evidence="10">
        <location>
            <begin position="34"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydrolase-related" evidence="11">
        <location>
            <begin position="100"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="9">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00036696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00039113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR611778-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0581849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="533" mass="57876" checksum="D6E3BED2E1444A0F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHZ1</accession>
    <name>A0A8T0IHZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G064500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14062" checksum="C0B9D2581D7A74C0" modified="2022-10-12" version="1">MSLDATQCDALTSPRACKFTKTVLQEVQPALPRQSSATTTLLLEKRETKTTTLQKTQSSQIPNFYPLQTIIKQTLPLLLRQSLDVYTKAMHTNSLSRHYSSSTAPVVLLPSSSTNTQPPSSRLITNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IID2</accession>
    <name>A0A8T0IID2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G051400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IID2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035720332" description="Secreted protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13119" checksum="5584347B30B011AB" modified="2022-10-12" version="1">MQPNTTFFLLPRLSLHALVLSPMAAHKGTPSPWPISLIQISATAPVIRSSACRVVLCTHLLVSSHSSSTSQSTPNCHLTHSISPLHQDSPSTSVDSRSRVSRISTRNVDSITEDCFTGTLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIZ2</accession>
    <name>A0A8T0IIZ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G122500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="183"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="207" mass="22558" checksum="DBD2AE107826C0DD" modified="2022-10-12" version="1">MAHVRGRESRCECTLPCSLHLTVFILGGTGLSLSILVTVAAFLSDDRYRAHSQAEKYSAIWLLLTTIVVCVSGLQGLLVRPDSCCFNCHSVLAVISLANLGVIGVSSLFVGNVFWIIYLVLVFVFELWVTVLRTCCKRQVGEVGMTGMELPIASPARHQEVVTAMPASVQHVVGIPAPSQPYKVDRRPEAAGSANSHLGYERFDEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJC4</accession>
    <name>A0A8T0IJC4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G102200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="19793" checksum="DD2C1549B38BA993" modified="2022-10-12" version="1">MLPAVPEQLIPALVIPASPEEEFVPAVPGEVIPDVCRAEDKVYPGDDEEDDPDNIFIPQSGNFPECEDGTNNDDAEDNNNDSNQKSAGPVRNTSRFRELDEKELKNTSMGGERRSLHSEIWARNAFDEWRRFRGISTEKTIGELSEEKDIRGFVELLHDFALQVTKQDGSLYDPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKW9</accession>
    <name>A0A8T0IKW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G209000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="14854" checksum="0F1463630337C91A" modified="2022-10-12" version="1">MARGSERGRGDLRPLPTIPRVQGHSTTIALDAGPRGYEPPSPGLGPVTHFHYSILSLPSPGTPGRVITRRRYEPSSPGLEPVTRFHYSMLPPPSPGPCPQSPREQGHAAPPSPRGWAASLHGVVANHHHRAIPVGDDRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM09</accession>
    <name>A0A8T0IM09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G200100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM09"/>
    <dbReference type="OrthoDB" id="689350at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22814">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22814:SF336">
        <property type="entry name" value="HEAVY METAL-ASSOCIATED ISOPRENYLATED PLANT PROTEIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="198"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="43072" checksum="A252E417CC330A0E" modified="2022-10-12" version="1">MPINLMSMEDLFYGPPETTYIIPTPEEAPPRRYIEREIREREIIEPPRRLYQPEPPRPVARYIEPPSPPAADREIRPIERLARVHTVPEPVAIRAPHEEIRKVVEVPVPVVDREIRPIERLARIHTVPEPVPVRAPHEEIRKVVEVPVPVPVEVPVRVEAPPRIIERVVHVPAPAPPTPVVEVVKRSITPPIQRPVVYHPIELKVPMCCEKCAKKVKDRLLDLEGVENVVTDQYNQKVTVYGHVDPARVLNRVKLVKKRSAFWDMTVDYSKEYRRFREAQAEAARADAARVEAAKAKAHAKAVETHAKAMVASSSPVTVVVNLPQEHHGPKVTAILPGTKERAMPYAVSSRTHSHRYVSPPRAYRQEFYNGRHADSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMK0</accession>
    <name>A0A8T0IMK0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G196000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="10057" checksum="297D8F3EFE8B0D5F" modified="2022-10-12" version="1">MQCQCALLNSHSRLCRFVFRVSVQRSVRHRHRHRHCHRWSTIVVESPCARLRPRQFLSRLTYGASSPVGEEQGVNCISHETPLAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQJ2</accession>
    <name>A0A8T0IQJ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G241900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000298">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000162">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989:SF37">
        <property type="entry name" value="INACTIVE PROTEIN KINASE SELMODRAFT_444075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989">
        <property type="entry name" value="OS01G0750732 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="566"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="287"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="342"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="895"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="292"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="902"/>
            <end position="912"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="946" mass="105199" checksum="4D339C66D4CCF2BE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRE7</accession>
    <name>A0A8T0IRE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G024200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endomembrane system</location>
            <topology evidence="10">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05476">
        <property type="entry name" value="pepsin_A_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034161">
        <property type="entry name" value="Pepsin-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683">
        <property type="entry name" value="ASPARTYL PROTEASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683:SF375">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 12" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 13" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035875856" description="Peptidase A1 domain-containing protein" evidence="13">
        <location>
            <begin position="24"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="80"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00046288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0585599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="450" mass="47174" checksum="A8CBBA1D82B4A58E" modified="2022-10-12" version="1">MEGNMEIIALLVILMTLTLTIEAQQFSLVHKYAHLEGSPANTQGQGVSPEYSALLKAHDRRRLDAFFPLGGSADLPIGLYYTEITLGTPPQNYHVDVDTGSDVLWLNCAPCSNCPLTTTIPGITLRHYDPTLSSTDTALGCTDANCAVASYGNPGQCTVSPPGACAYSIGYGDGSTTEGYIINDIITFHDSATTTAGANIYFGCGTKQTGNLLESTSAVDGLIGFGKAAISVPTQLANQGLVSHVFAHCLQGDTVGGGNIVIGNITEPGITYTPMVPGTHYNVALQNIGVNGVNVTDPTSFEITASNEGVIMDSGATLAYLIEPAYDQFVAAIESGAPVPSERISDGNGGYDLCWSYSGDIATTFPSVQLFFDGGAVMNLAPTNYLYLQAPTSGASAYCMGWKASTGTVSAPGYTLFGDIVLKDQLVVYDNTNQILGWKPFNCSQPIPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU46</accession>
    <name>A0A8T0IU46_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G107700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="3816" checksum="EB9B33E22BB82965" modified="2022-10-12" version="1">MYSGSGCESVECSSVVECVGFGSERCMTQDFVTLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVW5</accession>
    <name>A0A8T0IVW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G196900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34574">
        <property type="entry name" value="CALCIUM-BINDING EF-HAND FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34574:SF13">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="354" mass="38247" checksum="26BFB6C5F9312C3E" modified="2022-10-12" version="1">MADTLMDGKSLKQFVENDQLWAKFVDERFAKLDKGHTGKLTHTDLEPAISGVGKALGLPPMGNDPETDHIYSEMFSEFGPGGEGITKETFSIVMRDILLGLGDGLEREPVAISPLNGSELERWVRSPQFDIEAAAAYGALDTDSSGQVKANSIIKAMRRLSVDQGMPPPTDVSVSKNIDRAMQEAGINAEQNLGQLEFADAYRKVALAVAKYMREKPMTVAHTEKVFDGTSISNLLKDKHALDLALDLAWEIMPKTGNGSAPKSYLRIGLDTLAPYAGLPPVGAVPEMDNIVNDSFKLIDDDAAGRVDKPAFDKCMLEVLGGVMLQLEGKNIGVRSSAVIPPGRENSINTGMPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWY8</accession>
    <name>A0A8T0IWY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G164700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37758">
        <property type="entry name" value="OS03G0334300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37758:SF1">
        <property type="entry name" value="OS03G0334300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="30234" checksum="1E6885427D987BC5" modified="2022-10-12" version="1">MAVCKMEMLAVGSRVVVGRELGSELGGVCGRRDAVGLRSVKGQGRVVLLRADEGRRSSGRVRVVVQASGRVEFRCKAASGDGKSSKGYDVSEVVEKVVHDEKNQLPEEDKKTPEPLPEGEPSPFSPAIETDETEAEAFQGEGVSKDSMIEPPRGLQEGAASASIGKGLGASEESALTADIGGSPVSGPGGHGRDWRAQSSRESSKGGLSKARVEKAVGTEVHPGQQKQMFGPSEASCDDGSSFMAEAVILETDGGKSVDDYKMRAQIFSESAVFFSALKKRESHHVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXV7</accession>
    <name>A0A8T0IXV7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G175500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5981" checksum="D5AFBA56AF3C364B" modified="2022-10-12" version="1">MAKNYRPRGEENVFSVGNKNNVIYRRSIRRPYRTISLRASSSSGCSILYKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZS1</accession>
    <name>A0A8T0IZS1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G229300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="38" mass="4476" checksum="C6BF27F825EBF756" modified="2022-10-12" version="1">MQRALQISNVFTLGLNFHQYTNSITFRHSMTVLNILCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0C8</accession>
    <name>A0A8T0J0C8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G254100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0C8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="14046" checksum="04FDA46E614F87CC" modified="2022-10-12" version="1">MATPLAQPPKTNIPTSTNDEVSRNCSNSLLKTHTAISWSTLLHRSTALPTTSPSPTERSSQFHHPNMNHTWNAPHGDNNRIVRYQKADIMSDGLKSSSDIRNQASCLMDSTVWHHSRDGFLEMRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0H6</accession>
    <name>A0A8T0J0H6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G257400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0H6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="126"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="50554" checksum="11E27FF79AF0790D" modified="2022-10-12" version="1">MGNTNSRVRHLPDVFCVCMGRSSEARDVAGSAAEDAASSPLPHLANRSASNYLVGEVSSESVEQQIEQSMLHWSQLTDFDSACIDEEDVEADNMKVFLALQSDPSTRDFFQTFGYDTEEWESVGSLEMGHKFAEGGQAELFHAYVTWSGSNLEMKEWDREHGREWVLKVFKKGTRLRHLQSQWPHGMLKYHDERVANWESPTPIKHPRFFCHVDCGTLLGDGRFAFLMKKEHLDLRRLIDDKMKVISTNNYGPFSKEVGEELMFEVALGMSWLHSRGIVHRDFKASNVLVEVHVNGHFQCFVADYECSIGVVGTGLFRAPEILEACKERSVGKRPELFTMASDAYSYGMTCYEIMTGKLPFDGQSRIDIMDVATGGKRPEVPEYVDEWVHKLLCDCWEHDPAKRPSFGEIVNLIYSNSSRIRRSVKNRTYDFGRMDWIKLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1B2</accession>
    <name>A0A8T0J1B2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G042200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1B2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8173" checksum="264FC5628E76A970" modified="2022-10-12" version="1">MTIRGSTFHPLAVILAINGLYLLVLASNVSGENLSLQYVNSMNCMVRLGFISVGGSLWYGKPLTQRMSGLNLELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J538</accession>
    <name>A0A8T0J538_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G077000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J538"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37174">
        <property type="entry name" value="FORKHEAD-ASSOCIATED DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37174:SF2">
        <property type="entry name" value="FORKHEAD-ASSOCIATED DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="55"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="126"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="224" mass="25141" checksum="9669703CE1DB9D7C" modified="2022-10-12" version="1">MSMVMVHFTPTILANPLHCTLICTPRLKQQLAHNPFCSVFVKLAEFESRTRGKRIATWRVNAQAVNEELHSAEELRAQLEALRQEAERVRNRASSARMRFMRLTHVVEQLRQRAAVDVRMGKEDSARTLLSEKQKVMKALEAARQRAELLEQLAGKLNIAISIKETRLIATLSSAPLSIRPEPGADTGSVHHVSPRTTTTEGLNEGTSQSDGDDEDDMTFRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J686</accession>
    <name>A0A8T0J686_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UspA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G089000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J686"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23659">
        <property type="entry name" value="USP_At3g01520-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47583">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47583:SF1">
        <property type="entry name" value="ADENINE NUCLEOTIDE ALPHA HYDROLASES-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035940437" description="UspA domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="UspA" evidence="2">
        <location>
            <begin position="116"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="23279" checksum="81F70492C5E3C23F" modified="2022-10-12" version="1">MAKTADALLNGLLRIWCAWLTRFTLCMSCRPTVSLHNSSISFCLGGSEESNTWLRFPAVEAVVESLDWHRLLFESNCSVSLFVWVSRAITKKCRLKMYAGVAVHHGRSEESSAVLQATEVLFDKLQKEAYEVAMVKTERRIMEGEPGKVICHESARLEPVAVVMGCRGRGVVKSVLLGSVSEYCTRHCLCPVIIVPHKDDRLHELDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7X0</accession>
    <name>A0A8T0J7X0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="30">Acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="28" type="ORF">KC19_1G138400</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="28" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="28">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="21">
            <text>N(6)-biotinyl-L-lysyl-[protein] + hydrogencarbonate + ATP = N(6)-carboxybiotinyl-L-lysyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>hydrogencarbonate + acetyl-CoA + ATP = malonyl-CoA + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11308"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06850">
        <property type="entry name" value="biotinyl_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000005">
        <property type="entry name" value="Acetyl-CoA carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000043">
        <property type="entry name" value="acetyl-CoA carboxylase 1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1490.20:FF:000003">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.20:FF:000005">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000010">
        <property type="entry name" value="acetyl-CoA carboxylase isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.460.10">
        <property type="entry name" value="Biotin dependent carboxylase carboxyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1770.10">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049076">
        <property type="entry name" value="ACCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049074">
        <property type="entry name" value="ACCA_BT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013537">
        <property type="entry name" value="AcCoA_COase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CPAse_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728:SF3">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45728">
        <property type="entry name" value="ACETYL-COA CARBOXYLASE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08326">
        <property type="entry name" value="ACC_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21385">
        <property type="entry name" value="ACCA_BT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="13 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="18" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="17" id="KW-0464">Manganese</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="25">
        <location>
            <begin position="43"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="24">
        <location>
            <begin position="196"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="23">
        <location>
            <begin position="676"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="26">
        <location>
            <begin position="1510"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="27">
        <location>
            <begin position="1854"/>
            <end position="2167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00048600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="KAG0590948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="30">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2274" mass="250616" checksum="4D24AF2E44BA2903" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8Q2</accession>
    <name>A0A8T0J8Q2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G189500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8Q2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="9008" checksum="4386250F7CAEA83D" modified="2022-10-12" version="1">MPTTTIEFKHQQLHPIQKRTQQMQTLENQRSPTHPPQNRKLTHTITDPSQPRQGHEATYKRLKRTYSCMGPAFERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J955</accession>
    <name>A0A8T0J955_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G202700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J955"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="14837" checksum="D8F07EC005A0BFD5" modified="2022-10-12" version="1">MEYYDQSRPAGFAGPSVAPFNPEDEKKQVWAKLQALRNGYMEDMMELYGMLTSQSYQSVLRNRGSVDPLKDVVLPFCINVAGSVISPGLIFLCAFLFKLMMEWLRSHGRTSDADSGGQPLPQADAAHDVEMGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAQ3</accession>
    <name>A0A8T0JAQ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Receptor-like serine/threonine-protein kinase</fullName>
            <ecNumber evidence="21">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="29" type="ORF">KC19_1G219500</name>
    </gene>
    <organism evidence="29 30">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="29" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20 21">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19 21">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="21">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="21"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAQ3"/>
    <dbReference type="OrthoDB" id="643280at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048544">
        <property type="term" value="P:recognition of pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.90.10.10:FF:000016">
        <property type="entry name" value="G-type lectin S-receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000248">
        <property type="entry name" value="S-receptor-like kinase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000059">
        <property type="entry name" value="S-receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000858">
        <property type="entry name" value="S_locus_glycoprot_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024171">
        <property type="entry name" value="SRK-like_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47974">
        <property type="entry name" value="OS07G0415500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47974:SF19">
        <property type="entry name" value="RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01453">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08276">
        <property type="entry name" value="PAN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00954">
        <property type="entry name" value="S_locus_glycop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000641">
        <property type="entry name" value="SRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 21 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="18" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0430">Lectin</keyword>
    <keyword evidence="15 24" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 21 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-0675">Receptor</keyword>
    <keyword evidence="30" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 21" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8 25" id="KW-0732">Signal</keyword>
    <keyword evidence="6 21" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 24" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 24" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="25">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035860830" description="Receptor-like serine/threonine-protein kinase" evidence="25">
        <location>
            <begin position="27"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="24">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="27">
        <location>
            <begin position="32"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="28">
        <location>
            <begin position="343"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="26">
        <location>
            <begin position="511"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="794"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="539"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRNR" id="PIRNR000641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAG0592033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="837" mass="92389" checksum="3F125661E3E1B756" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDB0</accession>
    <name>A0A8T0JDB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G297300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="6020" checksum="AD0FC7D8EF21B4EE" modified="2022-10-12" version="1">MCCGVEAGVGMTMVPLLIVEVSRLSPQRTTVFFWRLERLRIDLQGSRLRSACH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G232</accession>
    <name>A0A8T0G232_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G002300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G232"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044240">
        <property type="entry name" value="STR4-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47377">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47377:SF1">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="140"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="22"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="35123" checksum="6828C605E51C4236" modified="2022-10-12" version="1">MELRLSGVSSSSACSTPQAECSSSGSGSSTAPSSSAPTSFSLRPSAFVAALVASSSSLVASVPPSLALKYDDFVRKADSVKSAASTSSADGSSFVDFVSANPVAVVAGVAAVAVPLIAFRASAGQSFGSVSAAAAFAKLSEQNAQLLDIRAPEDIKADGRPDLKLLRKKALQIAYVAEDKSMFLNRVVAKCRNAETTTLFVLDRLDGNSLAVAKLLASNGFQRVYAVKGGVEGTNGWQKSELPWVLPRKGFSLNLDGLKNLLAGSQSLAGLQSNANLGPTLGAAAAAGIGVAVFTEAETVLQLLGSAAFIQIFAKKFMFADVSLALYSWKKYYCLWNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G313</accession>
    <name>A0A8T0G313_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G001400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G313"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035923774" evidence="1">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5964" checksum="1503B1E5C69CB59E" modified="2022-10-12" version="1">MFMSALFVLLGRRGCQGCWSECLTHYRIYMARPSVLFATEAPMWKLVDTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3P9</accession>
    <name>A0A8T0G3P9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BRO1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G018500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3P9"/>
    <dbReference type="OrthoDB" id="64867at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043328">
        <property type="term" value="P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09246">
        <property type="entry name" value="BRO1_Alix_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09238">
        <property type="entry name" value="V_Alix_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.560">
        <property type="entry name" value="alix/aip1 in complex with the ypdl late domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.50">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.280">
        <property type="entry name" value="alix/aip1 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025304">
        <property type="entry name" value="ALIX_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004328">
        <property type="entry name" value="BRO1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038499">
        <property type="entry name" value="BRO1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030">
        <property type="entry name" value="PCD6 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23030:SF30">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13949">
        <property type="entry name" value="ALIX_LYPXL_bnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03097">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01041">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51180">
        <property type="entry name" value="BRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRO1" evidence="7">
        <location>
            <begin position="10"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="726"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="446"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="727"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="787"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="839"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0553535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="865" mass="96023" checksum="4CBF88764354E07B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5J3</accession>
    <name>A0A8T0G5J3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G032100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5J3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="314"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0553697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="670" mass="75981" checksum="84A4D9F0B7C5FAC5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA27</accession>
    <name>A0A8T0GA27_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G021000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF68">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4 HOMOLOG 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="57"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="422" mass="47232" checksum="CBFA3051279A47D5" modified="2022-10-12" version="1">MLQHRFAGVRTPFCRIVQKTYGTMTAAVPKWSPTFIPIQSPEQPEVSSSSPLVRIVSYNILAQSYVKSISFPHSPSPCLRWKNRSKAVLERLLSFDADVLCLQELDEYESYYRSRLTREGYSSVYIQRSGRKRDGCGIFFKRNRMELVEEQAIDFNDLVPPPTEVDTPELSSEDDPQTPDVSAPVKDSRPERSKSRSRSSSPTKAGPEVRGDPNDPRVRLKRDCVAILAAFRMLEAPNKCLILGNTHLYWDPEWADVKLAQARYLLLQTVRFQNNLSAKLDSNPLVFVCGDYNSTPGDQVYRYITSGSQESGAQQNGTLKGIVDESLESKFTELGLEEPSPERAPLHLTSLYEKALGEHPNTNVTPGFTGTLDYVFFRPSDSLRIVNLLALPDQGSPELEGGLPNHSHPSDHLPIGADFAVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBM9</accession>
    <name>A0A8T0GBM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G064600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22814">
        <property type="entry name" value="COPPER TRANSPORT PROTEIN ATOX1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22814:SF336">
        <property type="entry name" value="HEAVY METAL-ASSOCIATED ISOPRENYLATED PLANT PROTEIN 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="3">
        <location>
            <begin position="416"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="239"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="269"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="300"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="330"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="493" mass="54060" checksum="47602C55D4F23730" modified="2022-10-12" version="1">MAGQYFYDPRPFYGQNGSNGLMPMDELFYGPYEQVPYWMDQRMAPVSAFDDYYPGHKQMAMGRPPLPQLQQYAYKRPESRDDIGVDMYRRSPYNFQGVAAPMSYGGQQLRQAQDDTWVHAMTPNGYGQQHGNMTRNGNGKDQFQVPVGYNMPNGNMNGSRGMEMPMNNGHMNNKGNNMSNMGNMGNMGNNGNNGNNGSLGNKQMSVSSNQFAGNKSNGFGNGGNGGNAYGNGNKGYNGYENAKSSSQGGKSMNSMQGGNTKQRYSQDDSSSDDSDDEYGNSNKNGVKWATKNSVKHGNGHHNSSQKTGSKGNNYGYDSISSKHMSSKKSGGYGGKSGGSHGSTQSKISKLLGFGGDSSSSDSEDERYGLSRKSSKGGSKMSSHGSHGSYGNHGSFQNHSHGQQLGKQTLYTYSGQSKGVELKVPICCDNCEKKVKECFEYMDGVENVLCDQWNRKVTVYGNVKPENVLRRVRRVKKTAELWQQAKLQQQLRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC19</accession>
    <name>A0A8T0GC19_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G165500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC19"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="16818" checksum="4679D9DB84D99CFC" modified="2022-10-12" version="1">MLFGAGDGHFKPSHCHCHRHRHRHRHRHCHRFCVCVAVALGLPLPLPLLLFFSFLHLLCLTLLYSAPRAPGTFLTLPAFLSFFLSFFSLLSRQVHRLHFSRNAISWLRGHAKLPRTRSAIAGRQRDRDSQRDTHTERERQIDRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE59</accession>
    <name>A0A8T0GE59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Neprosin PEP catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G092200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1320.10">
        <property type="entry name" value="Outer-capsid protein sigma 3, large lobe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053168">
        <property type="entry name" value="Glutamic_endopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004314">
        <property type="entry name" value="Neprosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025521">
        <property type="entry name" value="Neprosin_propep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31589:SF223">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF239)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31589">
        <property type="entry name" value="PROTEIN, PUTATIVE (DUF239)-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03080">
        <property type="entry name" value="Neprosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14365">
        <property type="entry name" value="Neprosin_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52045">
        <property type="entry name" value="NEPROSIN_PEP_CD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035823242" description="Neprosin PEP catalytic domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Neprosin PEP catalytic" evidence="2">
        <location>
            <begin position="153"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS52045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="46320" checksum="E02BCE436BD811D6" modified="2022-10-12" version="1">MGSSKLYFALLCFQLIIGSTLAGRKLPSLENPKAIRLQAYTGCNGTHPQHAPPVKSFLVSDGTWVDCVPIEGQIAAHHPALKDHVIQMVPPKPARASSPKSIHPQLFAREHGGCPEGSIPVLRDDPMRKVRHPRAYKASTGGGYAAASVTDPATPTKPHEYAITGLPNISHAYSGAYSVFSVNAPTLGDESEMSLSQIWVTDGSYDLPGSLSTVETGWQTQPVLHPNDLPDAPHLFVFWTNDEYNKTGCYNLACPGFVQASNTWVIGGAMPKYTTLAQNAAAEFEVSYEVVYVPSDTNWWLYLDGVGIGYWPSSIYANGYLQGTANQVQWGGEVAIIRDSSVTTHSTTAMGSGAFPKAGYPKAAYQRNISYADATGSFFIPNPTGLDKRRRFNNPLCYDIQVQQGNFTNWGSYFFFGGSGGANPGCTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEB2</accession>
    <name>A0A8T0GEB2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G082800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="95" mass="10999" checksum="C5B92C24C6C9B68F" modified="2022-10-12" version="1" fragment="single">MGNKRNVHRRNEISVRRELRLEGDQRREQEALEAEEQERQRELRVAQKREHRRTWRTRARPSGGIPLGSSASDEGNSQPNSGEEPAVDLNDAENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGT3</accession>
    <name>A0A8T0GGT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acylphosphatase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G043300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268:SF4">
        <property type="entry name" value="ACYLPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="Acylphosphatase/BLUF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="4">
        <location>
            <begin position="75"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="162"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="167"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="196" mass="21501" checksum="6271A0E692042111" modified="2022-10-12" version="1">MNVETSEAGDSTKATAGGSTPENAMCSGMCTHFHVSTRKNEEYIKHLEEEQKIHSFERDGVATAIRSPHGNPVESVHVIITGKVQGVHFLPWAREQAKHMTINGWIRYVKDGSIEAVFSGKPASVDRMLDRCKTGPGYAKVTEIVADACDPPPGAGFQQLALFDPSKGPDKEKIKKPTAARRETSKFKLKKDEPNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIJ0</accession>
    <name>A0A8T0GIJ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G091400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIJ0"/>
    <dbReference type="OrthoDB" id="10265628at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000005">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF35">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="18"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0559261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="52902" checksum="B0A0DE82CCE3293A" modified="2022-10-12" version="1">MGSEATEYSVAEWGNQSLEVADEEIYNLIEHEKVRQCRGIELIASENFTSQAVIEALGSALTNKYSEGLPGARYYGGNEFIDQIENLCKARALKAFHLESDKWGVNVQPYSGSPANFAVYTALLNPHDRIMGLDLPSGGHLTHGYYTSNGKKISATSIFFESLPYKVNYETGFIDYEKLEEKAMDFRPKMIISGGSAYPRDWDYARLRTIADKVGALLMCDMAHFSGLVAAQEVNQPFEYCDVVTTTTHKSLRGPRAGMIFYRKGPKPAKKGQPEGAVYDYEDKINFSVFPSLQGGPHNHQIAALAVALKQVDTPLFKAYAKQVKANAKAIGDALMKKGYKMVTDGTENHLVLWDLRPLGLTGNKVEKVCELAHITLNKNAVFGDSSALAPGGVRVGAPAMTSRGLKEKDFEKIADFLERAVNITLKVQKERGKLLKEFNKGLENNEELATLKADVEKFSMSFDMPGFDVNNLKYGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJD3</accession>
    <name>A0A8T0GJD3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G044100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12237" checksum="9F5091BDC8B81264" modified="2022-10-12" version="1">MMSFATKQNNPWQHGITHSRTNLCGVSSGKAWWWWYCLGLGCAGEEVAIGVGLTEQEAFWQCFALIEVVPGEVSATFHRSQVDSQQLRKCTHVEWLGMMSGIIVLMRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK77</accession>
    <name>A0A8T0GK77_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G134800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006516">
        <property type="term" value="P:glycoprotein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000363">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007397">
        <property type="entry name" value="F-box-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039752">
        <property type="entry name" value="F-box_only"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12125:SF5">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12125">
        <property type="entry name" value="F-BOX ONLY PROTEIN 6-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04300">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01198">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51114">
        <property type="entry name" value="FBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="FBA" evidence="2">
        <location>
            <begin position="106"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34933" checksum="F8C65EB9DD42A682" modified="2022-10-12" version="1">MGGGRGVATCESVPDAVFAKIFALLPSAQIASSCALVCRAWRDYTQDATLWSELCEGSGLRAIDAMRCLGGWRGLFGSVYGLNLVASPHFERVHFYEADRLKHQSLRPWEPKHRLIIDRICSDNESDEETHSYGYWATEGGSVFQRGGGDGVLRECPALDCSPCPVAEREPVLATSWDWGKVQQYIGLQTFSNKFLDCSPPMMFSIWYAGKKGAPSVFKAQVVLRDELKNIIFVWESGELETTENVWKQEKHLIQNYPPGMRSIVVKAAGMSIQHKSGFHGAKFTAVKLQFVPVNEVPLHIEQPILGKKFSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKK3</accession>
    <name>A0A8T0GKK3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G048500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11514" checksum="DE19BAF0C1B5AE2D" modified="2022-10-12" version="1">MNSGTSSQFTTSRSHYSPVRRLSFCHNNVSPPTIIPNFLKIFLIPIMPKRSKLEHVSFSMFSLKHVLGSRFFSSHLSGSFTVFILSFYIEDLTYKYHYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKL9</accession>
    <name>A0A8T0GKL9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G078100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKL9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13469" checksum="9F57AED6AF6BFA63" modified="2022-10-12" version="1">MDHHDRNPASFPCLSPQFVATISVLVTTFSRTVCFSSPLDPSYPWTQKLLILLQNITERKIRLECVSNDKILTVILSLVGFQSGCVECLDQVCSWGVELASDEKKPPREEDSDSGEQLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLP8</accession>
    <name>A0A8T0GLP8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G138400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLP8"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="1">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11779" checksum="A75078B68AD90BF1" modified="2022-10-12" version="1">MEQKLYERSPINHLNKLTCPLILFQGLEDKVVPPDQARLIYNAVKEKGTPVALVEYEGEQHGFLKAENIRNTLEQEMVFYARLIGGFQVADDITAIKVDNFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM85</accession>
    <name>A0A8T0GM85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G097600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_bL35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_bL35-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_bL35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36400:SF1">
        <property type="entry name" value="RIBOSOMAL PROTEIN L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="L35p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0559334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="19406" checksum="DCB3882B3F37A1EB" modified="2022-10-12" version="1">MSGRQLLPRLLQRASRLASANSTQHIVHRPASCSLSTRASWLHGDGVATPASWLGSRSLCTRSVVPSSASMLPLGFRNGVNLAAREVGFTTAGVTYVQVQQRRMLSKLKKTKVKAYSSYKKRFRGMANGEYKRWRSGKRHNAHSKTNKQKRQLRRPSIAPLALAKVMKKLNFMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMD5</accession>
    <name>A0A8T0GMD5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G011300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMD5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035771288" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9482" checksum="65D3F51736D33174" modified="2022-10-12" version="1">MLPGGAHIRSLVVNLSLLYFWGSWIVHPCRERASNPALGYSSALQASPVLLRSHLLSLVSLCPGQGLFWCSAWQAAFRYTFYPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMR3</accession>
    <name>A0A8T0GMR3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G130300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015179">
        <property type="term" value="F:L-amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950">
        <property type="entry name" value="AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22950:SF685">
        <property type="entry name" value="AMINO ACID TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="12"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="205" mass="22012" checksum="84958BB995682847" modified="2022-10-12" version="1">MITRSSTVTRDAVIIGSTVIMLPAIWIRTFSRLTSISVSGVLSSLLLTTVVVISYAVDPNREAVHDTSSAIHENVNWTHLPIAAGILVASLSGHAGLPSMRRSMKNPQNFEHCLNVAFFSMFLLYATMGSISYFYFGGATQVLVTANLNDASGVTGFVLLRLGKLRITINEVVTVLVAMSAYSTIPALTYVIAELIVDTISRSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNE7</accession>
    <name>A0A8T0GNE7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G127400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the abscisic acid and water stress-induced protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNE7"/>
    <dbReference type="OrthoDB" id="10632357at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003496">
        <property type="entry name" value="ABA_WDS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33801">
        <property type="entry name" value="ABSCISIC STRESS-RIPENING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33801:SF24">
        <property type="entry name" value="ABSCISIC STRESS-RIPENING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02496">
        <property type="entry name" value="ABA_WDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="145"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="20162" checksum="2618AEBB163F68BC" modified="2022-10-12" version="1">MAHHGHHRREEREEEREEEREERYERRQEYGEEQQQGYGRRTDTQYEIDGGGYGRRTDEYEVQPGGYARHTVTEAEERLDGIQQARKHETTYQRTEYLGEAGAALGAGFAMYERHEEKVDPTNARRHKIEEEVAEGLAVGGAGTAFYGHHKKENSEEQLEELETGHKKHGWFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNT6</accession>
    <name>A0A8T0GNT6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G191700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Thylakoid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNT6"/>
    <dbReference type="OrthoDB" id="419533at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010207">
        <property type="term" value="P:photosystem II assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.810:FF:000001">
        <property type="entry name" value="Photosystem II lipoprotein Psb27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.810">
        <property type="entry name" value="Photosystem II Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01481">
        <property type="entry name" value="PSII_Psb27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025585">
        <property type="entry name" value="PSII_Psb27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038450">
        <property type="entry name" value="PSII_Psb27_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34041">
        <property type="entry name" value="PHOTOSYSTEM II REPAIR PROTEIN PSB27-H1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34041:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REPAIR PROTEIN PSB27-H1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13326">
        <property type="entry name" value="PSII_Pbs27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0793">Thylakoid</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00060385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0560593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="194" mass="20575" checksum="4AAFFE2D85C29F18" modified="2022-10-12" version="1">MASTMHLSSVFHSPCALTPHSLLPNSSTLSRTAVGAPCPPRQALPAVSCSASSSSSQSDIAPASVSRRQLSIATLLVSTFGGVGVALADADEDYKRETGDVIEQVRTTLALEKTDPNKAAAVAKLRQAGNEWVAKYRKSKKVAGKPSFSNMYSVINAISGHYVSFGATYPIPAKRKDRILDEVKDAEKALSRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ78</accession>
    <name>A0A8T0GQ78_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G000700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12221" checksum="1768F9CCD70AAD0F" modified="2022-10-12" version="1" fragment="single">MAWKRKRSIEAENPMGREPGPKLREGEGGGGGGVSETKTTTTTSDCQSRRAVQCQRSASASGPKQKERAKKSVHRRCQRAPAISTPSESVVERRLPSFLFLGKFGLAKGPLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSR2</accession>
    <name>A0A8T0GSR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G166200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025757">
        <property type="entry name" value="MIP1_Leuzipper"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23054:SF18">
        <property type="entry name" value="TERNARY COMPLEX FACTOR MIP1, LEUCINE-ZIPPER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23054">
        <property type="entry name" value="TERNARY COMPLEX FACTOR MIP1, LEUCINE-ZIPPER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14389">
        <property type="entry name" value="Lzipper-MIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ternary complex factor MIP1 leucine-zipper" evidence="4">
        <location>
            <begin position="106"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="3">
        <location>
            <begin position="495"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="232"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="102"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="394"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="718" mass="80448" checksum="B1F13B4B384CF83C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTM9</accession>
    <name>A0A8T0GTM9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G132500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13585" checksum="7A4E02F5FB79AE98" modified="2022-10-12" version="1">MHGTNYQTTKTPAARIQSLPQKIMREVLILCRRRRYVSFHLLSFSNFADSERLVMFPNLDRCYNPSPHVAESHQYPAHNISPCDMRCVSGNLSLLLLLLSLLITILCCSLSIISSGVVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTQ2</accession>
    <name>A0A8T0GTQ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_9G032500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTQ2"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="100"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="426"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0561038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="49092" checksum="0F60379349142595" modified="2022-10-12" version="1">MDEIFLHMRPRRALLQAVPAAESTAKNLVWVYIVVSIVGVIVLLVACCCAWRCYKVKRTQRPKGKPVPFREDTVSEVLAGGQTAVKVLPHETISQATNDFDLRQKIGDGRFGPVFQGEMPDGTEVAVRRLPLNSRQGKREFVKGVKNMTEAQHRNVVRLIGCSYTQSRLLVYEYLSNGNLAQILFDRRKTLDWNTRFDILLGVANGLAYLHEEPDSVFAHGDLKAGNIMLDKIMKPKIADWGLAALFRNDQGEVKPRNMVSVGYMAPELALEGQLSAKSDVFSYGILCLEILSGRQNTDINLLGTEMQSLLGWAWKLQDRRRQMEMLDNRLRDNCDEGQVLKVMGIALLSTQDSVPARPSMSHIVAMLRDEEALPKLPAKPEAIKSLGLSDQNVSGTFTSSFVTPKFVTPSKKWNSKKHRAGTSKAHADPSDREGLYRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW05</accession>
    <name>A0A8T0GW05_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G037300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052575">
        <property type="entry name" value="SSU_processome_comp_20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17695:SF11">
        <property type="entry name" value="SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="22946" checksum="8B996B90A50C4BC3" modified="2022-10-12" version="1">MSYFEPLSGLHEDGTQNDPKRQKRSNDLSKGREMNQASKLIQQLLSIEAAPLVLENCRQSNLGVTHIKVDVSAGRIPEAYVVPLVHAMIGVLRNRFSVLWDPAMDCLPALVDTVGATSWDVVIAYLQSSQEDCLSEPVLISRKREDAADDGLTIPQDVEGRLVSQLLEETESTDTTTLLTLVLRTLQKLPKFAEAKSRHSFHFLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWI1</accession>
    <name>A0A8T0GWI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_9G180800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005310">
        <property type="term" value="F:dicarboxylic acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006839">
        <property type="term" value="P:mitochondrial transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000030">
        <property type="entry name" value="Mitochondrial uncoupling protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050391">
        <property type="entry name" value="Mito_Metabolite_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45618">
        <property type="entry name" value="MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="118"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="11">
        <location>
            <begin position="218"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0562897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="32863" checksum="541E72F719A42AAA" modified="2022-10-12" version="1">MEWKGFAEGGLASMIAGFATHPLDLIKVRMQLQGEAVASPALAFALDGGRHGARSLPVSQPGPFGVGLNVARSEGVQALYSGVSATLLRQALYSSTRMGLYEYLKRQWRDDTQEGSGLPLYKKVTAALVAGASGAIVGNPADLAMVRMQADGRLPMNERRNYTGVGNALLRMVNQDGVLSLWTGSAPTVTRAMLVTAAQLATYDQIKDAITANHMVPEGLATQVVASCGAGILASVASNPIDVVKTRVMNMKVADGEAAPYRGALDCAVKTVRAEGPMALYKGFIPTVTRQGPFAIVLFLSLEQIKRVIEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWM2</accession>
    <name>A0A8T0GWM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">leucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_9G055200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Leu) + L-leucine + ATP = L-leucyl-tRNA(Leu) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWM2"/>
    <dbReference type="OrthoDB" id="15954at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07958">
        <property type="entry name" value="Anticodon_Ia_Leu_BEm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00812">
        <property type="entry name" value="LeuRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000012">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000056">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000077">
        <property type="entry name" value="Leucine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000011">
        <property type="entry name" value="Leucine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740:SF2">
        <property type="entry name" value="LEUCINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="LEUCYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="ValRS/IleRS/LeuRS editing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methionyl/Leucyl tRNA synthetase" evidence="14">
        <location>
            <begin position="169"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Leucyl-tRNA synthetase editing" evidence="15">
        <location>
            <begin position="350"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="Aminoacyl-tRNA synthetase class Ia" evidence="12">
        <location>
            <begin position="771"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="domain" description="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase anticodon-binding" evidence="13">
        <location>
            <begin position="858"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="599"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0561322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1008" mass="113106" checksum="B951E0B73B69FC61" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX82</accession>
    <name>A0A8T0GX82_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_9G139400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17971">
        <property type="entry name" value="DEXHc_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21691">
        <property type="entry name" value="GH2-like_DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05684">
        <property type="entry name" value="S1_DHX8_helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000061">
        <property type="entry name" value="ATP-dependent RNA helicase DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000101">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000191">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044762">
        <property type="entry name" value="DHX8/Prp22_DEXHc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049588">
        <property type="entry name" value="DHX8_GH2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049621">
        <property type="entry name" value="S1_DHX8_helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF85">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="12">
        <location>
            <begin position="265"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="576"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="757"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="132"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="132"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0562348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1219" mass="138604" checksum="2F200D889908F95F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXP7</accession>
    <name>A0A8T0GXP7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thylakoid lumenal protein TL20.3, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G050000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.80">
        <property type="entry name" value="E3 ubiquitin-protein ligase SopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053285">
        <property type="entry name" value="Thylakoid_lumenal_pentapeptide"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47121">
        <property type="entry name" value="THYLAKOID LUMENAL PROTEIN TL20.3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47121:SF2">
        <property type="entry name" value="THYLAKOID LUMENAL PROTEIN TL20.3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141571">
        <property type="entry name" value="Pentapeptide repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="29720" checksum="C9E55EC576FDF90C" modified="2022-10-12" version="1">MALNVATVGSAVPGTVGVGAFSASRASASQLYQAQGVQLRKSQRDGACVCEVSESKEAVTSDVSSVPSEKRGGLRQAMAAALAAAVLGTSMDALADLNSFEANTRGEFGIGSAVQFGSADLKKTQHANENFRRGNFTSADMKEADFSGSTFNGAYLEKAVAYKTNFSGADLSDTLMDRMVLNEANLTNALLVRAVLTRSDLGSAIIDGADFSDAVLDLAQKQALCKYASGTNPVTGMSTRKSLGCGNARRNAYGTPSAPELSAPPPILLDKNGFCDKASGKCDGTGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYQ3</accession>
    <name>A0A8T0GYQ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G052300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYQ3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF277">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HT1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="175"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="441" mass="49626" checksum="5EE697ACAB4A14DA" modified="2022-10-12" version="1">MARHKEKLTITEPVHHGKLHIGGFHPRLPFFAGHHKPEHKTKTIPLGVHFTGPRKSHDDQAAQAEKAAQKTKSRSLESSPEKSTSPVRTKIDGSSSAGGSYAWLTKQKSANDSLPRVNSMESQQPMSKHHKKIKFPDMKKSASWAHFVEVASPQVEAPHLEMEVPEAYVCDMSSLFLGQKFASGNHTRLYQGVYKDQDVAVKLLRLDSCEDTAVAAKLERQFMQEVHCLSQLHHPNIVKFMAASWKPPVCCLIMEYVPGGSLRAFLHRNESGSLPMKTILSMALDVANGMEYLHSQGVVHRDLKSENLVLTEDLHLKLTDFGVGCLETECDLRSADTGTYRWMAPEMISHKHYSKKVDVYSFGIVLWELVTGLLPFEDMTPVQVAYAVVNKNLRPTIPDDCPAALRHLMEHCWIANPERRPNFYQIVQTLEDLDNPLSEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ13</accession>
    <name>A0A8T0GZ13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G187600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="7">
        <location>
            <begin position="107"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0562988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="312" mass="35554" checksum="4F779FFD456061C1" modified="2022-10-12" version="1">MGSWWSSAGGNTSKSTLPFGITKISNSVYSFNLNSRRPEMEIVFIHGLPISDNKEEFWKTWTAEEKDGDGNEVIWPVKWLREEFPRTRIWSLRYDSSTLKINPAGKIDGFTVGENLVQEMVNIAKVGQQSNQCPIVFVCHSLGGLVVKEMVIQAQKKCGRNKKYANLLQNIRGFHFYATPHDGSKLADLASHLPDMEEMVKKLKVINDDLGRLNGEFERIGKEQYDNKWQFAVIAETMKTESHGFNAKVVEKASAQHGYNRFSAVKADHFGVCKPENRTSKSYKTFREFILDIGMEAQTLTWVNPPENRLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZA7</accession>
    <name>A0A8T0GZA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G154400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13553" checksum="F750793AB3AC791A" modified="2022-10-12" version="1">MKHSVSQINGDRSTSTCHSGSRRAETSRTRYYMRVKVHKENASKPRNGNKQACCKKHTSRKHKKQTNKPIKLTKHKHDKHEPHHKLTNMKRKHKTTSDRKPQDTTKLANKHEGKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0G9</accession>
    <name>A0A8T0H0G9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RIN4 pathogenic type III effector avirulence factor Avr cleavage site domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G162000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040387">
        <property type="entry name" value="RIN4/NOI4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008700">
        <property type="entry name" value="TypeIII_avirulence_cleave"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33159:SF101">
        <property type="entry name" value="OS04G0379600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33159">
        <property type="entry name" value="RPM1-INTERACTING PROTEIN 4 (RIN4) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05627">
        <property type="entry name" value="AvrRpt-cleavage"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIN4 pathogenic type III effector avirulence factor Avr cleavage site" evidence="2">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="237" mass="25596" checksum="A39B2AFB4B225BB3" modified="2022-10-12" version="1">MAPEASFVLKRGEGLHNTNMIKHKVVYIETPRTSSVGSTPKMIPLVGSDSTRPVKSSYVSPMQRAREERKRREAGQSKDWDETSSSPSSEMSTISNGGTPPSKPARVIPHSGGLIPKSGGLIPKSGNLIPSSGNLIPSSGYIAKPRDSVSEEDGASRRLPKFGVWDNQNDASGPCYTLLFESVAQEKRIGGPIRVHANRPSSPAQSEDLYNYNPGAIKTRKSKLQLHHSLLCCFVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1Y6</accession>
    <name>A0A8T0H1Y6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G184400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1Y6"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF144">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035960215" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="24"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="291"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="394"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="516"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="552"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0565350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="591" mass="68248" checksum="88FAE4FDD3E85BFC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H267</accession>
    <name>A0A8T0H267_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G190100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="237"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0565430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1397" mass="154657" checksum="BE3346CA494427A7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2X8</accession>
    <name>A0A8T0H2X8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">HSF-type DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G111800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the HSF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2X8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000037">
        <property type="entry name" value="Heat stress transcription factor B-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000232">
        <property type="entry name" value="HSF_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015">
        <property type="entry name" value="HEAT SHOCK TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10015:SF304">
        <property type="entry name" value="HEAT STRESS TRANSCRIPTION FACTOR B-4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00447">
        <property type="entry name" value="HSF_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00056">
        <property type="entry name" value="HSFDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00415">
        <property type="entry name" value="HSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00434">
        <property type="entry name" value="HSF_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HSF-type DNA-binding" evidence="10">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0564458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="420" mass="47209" checksum="0287E5CBA91B9DB1" modified="2022-10-12" version="1">MSLSFDNSEAGCMLFYDCHRSVPAPFLTKTYHLVNDPSTNEIVSWGEDDTTFVVWRPPEFARDLLPNYFKHNNFSSFVRQLNTYGFRKVVPDRWEFANDFFRRGERHLLCEIHRRKALQPASGTSGSAQLSRSLSPSTSVEDQAWASPISSPLPSPIPVHIVPTHHSPPITTPLSISDENERLRKDNNLLLSEVSRLRRLYEDTINMIQYQFKGSSPDFTTPSRIGPGGQPLDRAMSTVTALSGESAMHHWDRLGPVPARREENRELSVHVSNPTSNHEVYFCKNVPPSPHLIVPQQQHQQVEIGDSKLSFYSENSPSSPTLSSKAEVAEGAGKVPVKLFGVPLHSQGNLDPVPWTPALAGTKRQQPETWDVSEQPHDRVFLRPPPRKCLRTSEMASELSSTVQAPWLQICATRDEGVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H370</accession>
    <name>A0A8T0H370_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G174900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H370"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035853300" description="Secreted protein" evidence="2">
        <location>
            <begin position="33"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8413" checksum="28EE8A1A32C02B38" modified="2022-10-12" version="1">MAISFPYLFRIPFRRLCRALLLQLLCIRSRHSASFPFSFASSAFLPTLYTSTLTSPLPGALPRAPLGTRAPPAPYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3W5</accession>
    <name>A0A8T0H3W5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G157600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="268"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="775"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1504"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1504" mass="169601" checksum="82AD0F5856F772CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5L5</accession>
    <name>A0A8T0H5L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TraB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G036600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5L5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF15">
        <property type="entry name" value="TRAB FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="63391" checksum="5C7FDBAADAE14DA8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N2</accession>
    <name>A0A8T0H5N2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TNase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G078300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035437">
        <property type="entry name" value="SNase_OB-fold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016071">
        <property type="entry name" value="Staphylococal_nuclease_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302">
        <property type="entry name" value="EBNA2 BINDING PROTEIN P100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12302:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00565">
        <property type="entry name" value="SNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00318">
        <property type="entry name" value="SNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50199">
        <property type="entry name" value="Staphylococcal nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50830">
        <property type="entry name" value="TNASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TNase-like" evidence="5">
        <location>
            <begin position="197"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="383" mass="41738" checksum="1333B2CD15BA42AD" modified="2022-10-12" version="1">MGNIIRRCCGEFSTSDGYGANGQYPGQYPGQYPPGRYPGQYPGQYPGQYGPQGGASGYPGAYPGGGASDTAGFTALARDLFEFETTNKVPDALSQFVTATKATQVAWYRKLLAAWKSARPPPASAEEASALLLRTLQGHHNVHVQGLLRFYGLPGSKTDVPGGGAPHQPPVAFVAGGVWPQGVQYEIHTLPVDDRAVTDGDTIAVFVDVHKDAREAANVPVGIMDAVNRRQAARAQHNYVTADALQKQIQQAGYRVIDGKNGGTHCLAKKYRVRLKGVDAPESSQPHGQQSKAFLNSLVEGHPLLIHVYTVDQYGRLVGDVHCNGIFIQEALLKRGCVWHYTAYDKRPTFAKWEADAKAARVGLWAVANPEKPWEYRKDRRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6M0</accession>
    <name>A0A8T0H6M0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G102400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6M0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="13853" checksum="8F5B924BED8A83E0" modified="2022-10-12" version="1">MAVKCKNRFDVFVQRGMQVDTDYSVSKNYVPTYAKQTSMSITLFSSGDDAPRYTEGENVCKEEITFVVRWPDQDLDRERQVRMTMYFGRSTVELKAHGVNFGENKVHEMLCMRLNGDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB82</accession>
    <name>A0A8T0HB82_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inner centromere protein ARK-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G065200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytoskeleton</location>
            <location evidence="2">Spindle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the INCENP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005819">
        <property type="term" value="C:spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005635">
        <property type="entry name" value="Inner_centromere_prot_ARK-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13142:SF1">
        <property type="entry name" value="INNER CENTROMERE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03941">
        <property type="entry name" value="INCENP_ARK-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inner centromere protein ARK-binding" evidence="9">
        <location>
            <begin position="1916"/>
            <end position="1970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="117"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="214"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="294"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="443"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1291"/>
            <end position="1328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1481"/>
            <end position="1563"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1575"/>
            <end position="1664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1717"/>
            <end position="1740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1804"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1895"/>
            <end position="1936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="225"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1481"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1554"/>
            <end position="1563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2011" mass="218934" checksum="333D96C809E47499" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBH8</accession>
    <name>A0A8T0HBH8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G007500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBH8"/>
    <dbReference type="OrthoDB" id="10261749at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052765">
        <property type="entry name" value="PGM-Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46192">
        <property type="entry name" value="BROAD-RANGE ACID PHOSPHATASE DET1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="38280" checksum="56D1CC5D1167F21F" modified="2022-10-12" version="1">MAEDGRTRRPTRIILVRHGESEGNVDQKKYCHIADPKIRLTEAGANQAQKCGQKIRNIIERGSPKDDWLVHFYVSPYTRTLCTLKEIGRAFEKEQIVGVREEPRIREQDFGNFQNKNQMKMVKEIRQRFGRFFYRFPEGESAADVFDRVTSFLESLWRDIDMNRLNKHTNQKEVNLVIVSHGVTMRVFLMRWFKWTTQQFEMLNNPTNCEVRVMQLGEGGEYSLLVHHTEEELKHWGLSQEMINDQKWRKTTRRGQWSDHWPWSGTQFFDNYKEDICSPREIEAAEELTEENYCLVNNNGICHDVEPDLSQTPLEMVDLTSSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBI8</accession>
    <name>A0A8T0HBI8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Prefoldin subunit 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G008500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBI8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990113">
        <property type="term" value="P:RNA polymerase I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990114">
        <property type="term" value="P:RNA polymerase II core complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990115">
        <property type="term" value="P:RNA polymerase III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23157">
        <property type="entry name" value="Prefoldin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00293">
        <property type="entry name" value="prefoldin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674:SF2">
        <property type="entry name" value="PREFOLDIN SUBUNIT 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="153" mass="16810" checksum="08C742FA938C4199" modified="2022-10-12" version="1">MATPEAMVEEISKLSVDQLRQVKEQVDGEVSVLQDSLTNIRTAANRFEMANKALKMLSQQPPGKKMLVPLTASLYASGTLANTDNVLVDVGTGYFIEKSLPDGKDYCERKITFLKENHQKLVEVANGKQNAAEQINMVLQAKMRAAGAQAQRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD45</accession>
    <name>A0A8T0HD45_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G030500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10995" checksum="76EC4F920A8747EC" modified="2022-10-12" version="1">MAASMARRTGYAPGTRSADRAQKKTDCAAPLPLPLRKLFTNASSAQMLRNSNRERRCSQSVLRAFPAPATRFTRSPRRACAGFLTIIGALSYTIVTELACC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HES9</accession>
    <name>A0A8T0HES9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TauD/TfdA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G140400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TfdA dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HES9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016706">
        <property type="term" value="F:2-oxoglutarate-dependent dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.130.10:FF:000002">
        <property type="entry name" value="Alpha-ketoglutarate-dependent taurine dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.130.10">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051323">
        <property type="entry name" value="AtsK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042098">
        <property type="entry name" value="TauD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003819">
        <property type="entry name" value="TauD/TfdA-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007104">
        <property type="entry name" value="PRK09553.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30468:SF1">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT SULFONATE DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02668">
        <property type="entry name" value="TauD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TauD/TfdA-like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="280" mass="31422" checksum="6B51B3EAAB81DF10" modified="2022-10-12" version="1">MTLKITPLTATIGALVEGISLAEPLQSEQQAAINSALLQYQVLFFRNQPITPHQQHAFAKSFGDLHVHPIYPNLAPELEEIMLLDNDGDHPPDNAKWHTDVTFIDTPPTGTILSGKLIPPVGGDTLFATGIAAFEALSKPLQQFLLGLKAEHNFLKSFAQPRYHYKGQGDKKALWEAAVKKNPPVIHPLVRTHPESGRKALFLSQSHLTRIVDLHQAESDALLGFLFAHATKPEFTLRWKWQPDDLAFWDNRVTQHYGVADYLPNRRIMHRATILGDKPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGG4</accession>
    <name>A0A8T0HGG4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RIN4 pathogenic type III effector avirulence factor Avr cleavage site domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G111900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGG4"/>
    <dbReference type="OrthoDB" id="1109067at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040387">
        <property type="entry name" value="RIN4/NOI4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008700">
        <property type="entry name" value="TypeIII_avirulence_cleave"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33159:SF101">
        <property type="entry name" value="OS04G0379600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33159">
        <property type="entry name" value="RPM1-INTERACTING PROTEIN 4 (RIN4) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05627">
        <property type="entry name" value="AvrRpt-cleavage"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIN4 pathogenic type III effector avirulence factor Avr cleavage site" evidence="2">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="RIN4 pathogenic type III effector avirulence factor Avr cleavage site" evidence="2">
        <location>
            <begin position="206"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="30800" checksum="29790B6A2B9EBAA4" modified="2022-10-12" version="1">MARPHVPKFGTWDANGGNGSAYTAVFDHARAGKGQKMINPNDPSENPDLAAQIGGPAPAQRNNERPPPRYRTAPNDSDENRPRQEMRSSREDMDVRRSSDPPGRQAPSHDQPPPRRAPGGGRGGAEPPHRRTQADRDSEGSGPNPERSPAHPQANRMREAGRGAASPAWDRRGRHPSGGDEGSVLGSGAPKTRLRPQGGREEPPAKGGALPKFGAWDVKDPNAGDGFTMIFQKLSNEKKEGGPVHIPRLNSDQTPSNEGSYGQQSQSGGPRKMQNKPTKQPACCIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIX9</accession>
    <name>A0A8T0HIX9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G150800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000255">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="79"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0570282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="521" mass="56881" checksum="F09828322496CB81" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK10</accession>
    <name>A0A8T0HK10_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plant heme peroxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G213700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK10"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1620:FF:000001">
        <property type="entry name" value="Thylakoid lumenal 29 kDa protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF34">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="3">
        <location>
            <begin position="108"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="355" mass="38208" checksum="CEDD5E6F92063BDD" modified="2022-10-12" version="1">MAAVATTHALSAPALASRGAAASSSFLGGSAVVSVSPRTAAPSNGTKVGVRCQASEKDEVTVTRRDVFVGLTASVVAAGVWTSTPGGQEAQAADIIQRQQRGIFLNSLKDKLRVEIAAKPEIIPDLLRLAINDAMTYEKETKTGGANGSVRLELNRPENKGLEKAISFLEPIKQSIDEAAVTKGGPISWADLIQIAAQSAVKRTFIQAAVRKCGGDQKKGENLYTAYGSTGQWGQFDKLLGRSDASEADPEGRVFDWETASTTDIKERFAKLSIKPRQIVVLSAFLGRDQAATEAKFAADPEMAPWVKKYQESRETVSQTDYEVDLITIFTRLSVIGQSINYEAYSFKPKGSIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HND5</accession>
    <name>A0A8T0HND5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG088900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HND5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="199" mass="21818" checksum="79AA391F666517BB" modified="2022-10-12" version="1">MAGEHAPLSNGRVVTFVGNGSVDFVDVENNGGVDVVVDTGNRENIPHVYAHSEDNVFHGRVEVWTRGVFREWLNSNHYYPVLEVEDFDIDVLGAEVLPAFFGTVLSSRGISFNIHALMNLYNSFDRMLRTFQIDHAIGLNRGVVRDGDAVRDGDAVAGEDGTVGRDRGAVIFSIRSDIRFANTRAAFMNAISGFPSGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNN0</accession>
    <name>A0A8T0HNN0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG092400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033579">
        <property type="entry name" value="TMEM128"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20479">
        <property type="entry name" value="TMEM128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="183" mass="20182" checksum="EE82E2D05068DB28" modified="2022-10-12" version="1">MSAERGRLLATVRQRYSFSPDYGGELGVGLSPSSPAPSSPAPLRRTAENLLWLAAAVFAIYYGDSRHHLFHALFYDPRIRSLFATHPQIRGQMGVDCTCRNPDCYPSGTDIIPAIFNRPLANLGLLDSPTAVHFVHGVCCDFTVSSTLWTRELSTLRLTIRVLLISNTLPVDRCKIRTSACCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQQ8</accession>
    <name>A0A8T0HQQ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG132300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11981" checksum="7D957C5D75DD5E2B" modified="2022-10-12" version="1">MFDGNEYNHLKEEKEEKRRLRDHKKLQLQILNEKDFLFGSKPSPSKNVINSRRAGTGSRASSFGGSQQSVPNGRLSFGNAIMQSGTPEYTRNANSDPMGPSAVKLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQT3</accession>
    <name>A0A8T0HQT3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG157900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7619" checksum="46FE72B168E0F034" modified="2022-10-12" version="1">MAGELQAGHCENCTGTKSKSWQGFSFQVKIAHSLSVQCTDQSRNHGRQLPCKVCCSHATLNHDQRAISCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRD7</accession>
    <name>A0A8T0HRD7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG166100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRD7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035882814" evidence="1">
        <location>
            <begin position="22"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6871" checksum="70F0922E303891B8" modified="2022-10-12" version="1">MLYRCDWFLIVVLLTLEFASFRKLNFDRCCVVLRNIIMNDDLLEGHHYSERTGFTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSR6</accession>
    <name>A0A8T0HSR6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG190200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSR6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="19999" checksum="A3AACD696A335C95" modified="2022-10-12" version="1">MDRVHKGYLQHNDISPGNVLLHFPEDKVSEVYIGVCDWGLASRVCETTPSRYGYPSDEARTEAFKERGSFVAPELWYTYGKPNSETSYETVRRRHLYTQAADAYSVGVVANMIWKDEDDFDLFKDTAGKARFAVALKELTNPDPKSRSTLRLVHATLTAPPYNFQIPESCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU18</accession>
    <name>A0A8T0HU18_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG250800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF128">
        <property type="entry name" value="UBIB DOMAIN CONTAINING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="292"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="732"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="740"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0574287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="831" mass="92901" checksum="50FE263EF89706E3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUI6</accession>
    <name>A0A8T0HUI6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG284700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7564" checksum="7A40086A9C9A5CED" modified="2022-10-12" version="1">MIQGYLGLQTNFLCVGCRSIPVTRWTLADRDKGRILILDRRCSLTLQPVLRQHSAMIRMPSHNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUK7</accession>
    <name>A0A8T0HUK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Signal peptide peptidase-like 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG268800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF22">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0574526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32712" checksum="F514D4667C60A932" modified="2022-10-12" version="1">MFYLFSSVSMIIMAFTLVSSVLSLGFTLAPYVTALNARLGDVVVISRSWFGPITRSQAALALFCVGVVTSWMVTGHWFLNNVLGISLCIAFVSHVRLPNIKVCALLLACLFVYDIFWVFFSEQLFGSNVMVTVATRQTSNPVHTVANSLNMQRISEVVVKKLDLPLKLIFPRTFWDVSSGNFRSQYLMIGLGDMAIPGMLLSLVLCFDHRKFREHDNEGTFSRGNKYIQFDGCGYALGMIAALAAGLLSQAAQPALLYLVPSTLGSILCAAWARGELAELWSGPRPIVTEKTSFLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUL1</accession>
    <name>A0A8T0HUL1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG261200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="20841" checksum="2F647521460BE19D" modified="2022-10-12" version="1">MAGQQTLVKSLISMRSSVMSSGNGFQSHQPKIFAACVYHRYRQRSSTPKSPRQFHLLGRGCERSMVTSSSCTARETPASLTPCQTNQLFNSPTKETRLADFADFASPMYAPSSPDHAVKIEPADSLNRMQHFQYSYAAKEPTCTKFTLHLPPSPPNSSTVQRGCHRCNNCLRTTTLARHSLGMALKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVE3</accession>
    <name>A0A8T0HVE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldehyde dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG313700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVE3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:L-glutamate gamma-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07126">
        <property type="entry name" value="ALDH_F12_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000023">
        <property type="entry name" value="Aldehyde dehydrogenase 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000019">
        <property type="entry name" value="probable aldehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521:SF7">
        <property type="entry name" value="DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 12A1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="4">
        <location>
            <begin position="80"/>
            <end position="515"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0575052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="573" mass="63424" checksum="7CF58257E79D8E7D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVM9</accession>
    <name>A0A8T0HVM9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG288700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="11687" checksum="1166E2092FA997FE" modified="2022-10-12" version="1">MLPPLLTRVAGRGGDSSRLGVEWASPTIGGVGSRTRSKSKSSDSGGLFQNPGLDGALTFTGGLGGFSGGTGLSSATTSRIRSTMLYASKTISFISILGSRSLCLREFEVALACAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWA7</accession>
    <name>A0A8T0HWA7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG309700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035815105" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="13326" checksum="F0DF46BEDB24CAD1" modified="2022-10-12" version="1" fragment="single">GPLWAHRWSSLRLFLLFYSGLHPQISSSGTESSFFWQWHCHFLIYNILVPARLSHEMGSMVPYLLYCKLNHSNNLGKLEQQNSKIHQGNRLSAHQRSLVRSCTNSIDFLSHRFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWS6</accession>
    <name>A0A8T0HWS6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG297600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8232" checksum="F3AA443DA024E411" modified="2022-10-12" version="1">MFGVGVFSLPSFCVKSTVPSLAKMLSNSLTFAQSAIVYLNLCDYLGCKGTQVEDSVVEELRLPEACRKKSAPRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXU7</accession>
    <name>A0A8T0HXU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG326200</name>
        <name evidence="7" type="ORF">KC19_VG326400</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="57"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0575198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0575201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12141" checksum="5FA8205CEB3EFD00" modified="2022-10-12" version="1">MLSFLTLARTYVYEYVPNVLHSTYLGVMEDVPTAFWRSHGEDNLDGVNYTLTGPLASWVVKSSTYTSRKQTLCCFTKGWAGFVAANSVKIGDTLTFTKVGALEFRVTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZP1</accession>
    <name>A0A8T0HZP1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G057400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="12228" checksum="956F9ECB6AFE31BE" modified="2022-10-12" version="1">MMSRQRNFTTFRAFTDRESLVLIVVNIASFDHRDVLRWLLEYLDHNLLEHQYRQQQRAPRHSHCSEDRNTTRTCSTNSKHLSLVRNPEFYPEKYCNRYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0W1</accession>
    <name>A0A8T0I0W1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G087700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0W1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044837">
        <property type="entry name" value="REM16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391:SF4">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS03G0184500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS11G0197600-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0576535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="16114" checksum="21D011EB33C254E4" modified="2022-10-12" version="1">MAHAGILTEHYFVYTMSETHVYRDFHLVLLDHFVAGMSLPPSPTRLKFLDCAGHSWDVYSKRNVYNQFALHRTYWALFSLHHLLEEGDVCVFALKEIEPVRSVLVHIFRVVPVTSTDSTSVHSHYKTHEINATKTCTPNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I219</accession>
    <name>A0A8T0I219_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G112200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I219"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="166" mass="18491" checksum="31F044542900664A" modified="2022-10-12" version="1">MPPSSERVEAQKPKLITYITPPCLPSSLPPPSHDHPSTHTPTRTPPRNELLIPHYKSPPSCHRSSTLIKQYTRISSPRISMSQPLLDHHLTLRSGIEHHQLPPQFNTTSHNITQHLATPPNSTQHHTTPHNAMEFTSSPSKPTQLAPQSLTHIVLPTESSPSHDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2D3</accession>
    <name>A0A8T0I2D3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G137300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2D3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="42"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="447" mass="50993" checksum="EFF32B0097F25295" modified="2022-10-12" version="1">MRQLALHSGECSSTAVSCCDCYQTVGIAEGEAEKMSGFGTAGIAWSELPKDVQHKVLMNLGIQDLCRMRCVCREWRDVIHRRDFRGMYDVANSSQEPHPVICYLESSYPLRLQCTAYDYEGRMWKKMNSFPSVPQRSLTALNTCAHDEFGPLSNVGLYSVGGLLCLHHWSDHRRREYPRGVSSWTVWNPFRNRWKRLPLWYENSGQLIVGNSFVHAFVSDERTKAYKILMAHEVAVYPNNSEASARKLATKIYDSRTGMWTDGAEHTLGVELIYSTSSVRGVLCNGLVYFVAETRDFLNIGPTRPSVVLAYDISEDEWIEQPLNSYFVLFEWDGHLMTVDVDNAVLGWEEDFLEWEPVSRMWKETGIKMPGKIGKVFLSDLGGFSIVASGNHLAVTGHTRNDEFRIAVYKRAENYWRLPPNGKFSDKLMSFLVNGLVLHTPSLDWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I534</accession>
    <name>A0A8T0I534_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G171400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I534"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13399" checksum="F11E4047C63A416C" modified="2022-10-12" version="1">MISLRFGVLTSDVETGVHIYSLYRIRTSLSVSWFRDLGTRACLFGLHIGGSATAALKLISCISQFQGPHFGIWVHIRVCFPKWQFWLVIQMLCSFIESNIWIGIWNICFIARFQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5Z8</accession>
    <name>A0A8T0I5Z8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">thioredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Thioredoxin-dependent peroxiredoxin Q</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_5G193900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>a hydroperoxide + [thioredoxin]-dithiol = an alcohol + [thioredoxin]-disulfide + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peroxiredoxin family. BCP/PrxQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5Z8"/>
    <dbReference type="OrthoDB" id="338622at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03017">
        <property type="entry name" value="PRX_BCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000122">
        <property type="entry name" value="Peroxiredoxin Q chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050924">
        <property type="entry name" value="Peroxiredoxin_BCP/PrxQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801:SF4">
        <property type="entry name" value="AHPC_TSA FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42801">
        <property type="entry name" value="THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035840568" description="thioredoxin-dependent peroxiredoxin" evidence="16">
        <location>
            <begin position="17"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="17">
        <location>
            <begin position="67"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00038489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00042163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0577948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="22973" checksum="E1B2801C86F332E5" modified="2022-10-12" version="1">MAVSTSLSAALVPALAACSPSGREFATSSSVQVNSFARGEILGSRLNVSLAAARPVTSSRPLTTCKVSRGDKLPPLALKDQDGRDVKLSKFIGKPLVLYFYPANETPSCTKQACSFRDSYDDFRKLGATVVGVSGDSPESHKAFKKKYNLPYTLLSDEGNEVRKAFGVPADFFGALAGRQTYVTNRQGVVTLIYNNQFQPEKHVDETLKVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA13</accession>
    <name>A0A8T0IA13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G121100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47186">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47186:SF3">
        <property type="entry name" value="OS09G0267800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="119"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="516" mass="57965" checksum="52B81E5D930C85E0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAV3</accession>
    <name>A0A8T0IAV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G205900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAV3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37031">
        <property type="entry name" value="METALLOPHOSPHATASE BINDING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37031:SF2">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE METALLOPHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="188"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="614" mass="69010" checksum="C5E7A3345E1D5942" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB54</accession>
    <name>A0A8T0IB54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G154100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WEB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009904">
        <property type="term" value="P:chloroplast accumulation movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009903">
        <property type="term" value="P:chloroplast avoidance movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008545">
        <property type="entry name" value="Web"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32054">
        <property type="entry name" value="HEAVY CHAIN, PUTATIVE, EXPRESSED-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32054:SF31">
        <property type="entry name" value="PROTEIN WEAK CHLOROPLAST MOVEMENT UNDER BLUE LIGHT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05701">
        <property type="entry name" value="WEMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="196"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="658" mass="74127" checksum="883A616484464072" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBB6</accession>
    <name>A0A8T0IBB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PLAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G147600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010417">
        <property type="entry name" value="Embryo-specific_ATS3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31718:SF60">
        <property type="entry name" value="LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31718">
        <property type="entry name" value="PLAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06232">
        <property type="entry name" value="ATS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLAT" evidence="3">
        <location>
            <begin position="285"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="231"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="43893" checksum="96A37DBF9AC7D60B" modified="2022-10-12" version="1">MGFARARLSRAILTRVLYFLSSAGWFSNWKDTRKIVRKHGNLPRLSIVSSERFSNIHRCASNGTPRFFTKTLQDYTQFFTSVFGFCWVLSPSTSTPAFPYKSASSVHRRVHPPPSNASSPPPSLHPPSHPPPMRVHRFPPPPSSPPPPPPDEERSKLTSGKHSHNRRRLFSSEHVADPNSSSGREHSERNTFLTKADASPGKCTDADTGAPPAVTPLVPYGGGYIPVGAPFPYGDPGVPSPEPGPSPTSGVDGPSDNQPALPPVSGDNSTLAHTTMVSAMKLNQCTYTIITCTGNIEGAGTQADVNVEFFDKYGDSVLFVNLKSQNRNFNRGATDTFTVVGDCVQNICRMHLSHDDSGPNPGWFVNTVTVSLMYQTHVFNVFEWLAKDEPPYSLSRTVSSCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFU7</accession>
    <name>A0A8T0IFU7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G016300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="10657" checksum="9729D3B8FD178299" modified="2022-10-12" version="1" fragment="single">MKEGGLIISPSNQLVFGQDCQGYRVIIVKDISFQFVNAIVEAMNDAVDKIKWKDTEPDDLTSEFLSTVIMGVSSAISARTKSSDTVRSELLKACRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGG8</accession>
    <name>A0A8T0IGG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G024900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04216">
        <property type="entry name" value="Phytocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000034">
        <property type="entry name" value="Cupredoxin superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039391">
        <property type="entry name" value="Phytocyanin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003245">
        <property type="entry name" value="Phytocyanin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021">
        <property type="entry name" value="BLUE COPPER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021:SF193">
        <property type="entry name" value="OS06G0218600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02298">
        <property type="entry name" value="Cu_bind_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51485">
        <property type="entry name" value="PHYTOCYANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035759675" description="Phytocyanin domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Phytocyanin" evidence="4">
        <location>
            <begin position="23"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14200" checksum="BEBFB8F8F5514C76" modified="2022-10-12" version="1">MAMAGKKLVLVALLAMVAMCAAKEYQVEWKLPAAENTYSAFQQKPFNVGDTLKFTYMQEMHNVVEVGSEEDYNQCTMTKPLSPEFADGNTSMKLSKAGVHYYICSIPTHCADRIKLKVQAVDHQHHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGK7</accession>
    <name>A0A8T0IGK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TFA2 Winged helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G264700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005673">
        <property type="term" value="C:transcription factor TFIIE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001097">
        <property type="term" value="F:TFIIH-class transcription factor complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation at RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016656">
        <property type="entry name" value="TFIIE-bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716:SF8">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12716">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="14275" checksum="63C2C7BC88D47EA7" modified="2022-10-12" version="1">MPSDLLVLCTDLQDLKATGKVWVLMNSDSQEEILYPNDPKIVITVDEDLKQLIRGIDTPREFMDVERELQKAGMKPATNSARREAMAGVPRSQIPKPQKKKRRESKRTKYTNAHLPELLQFSVPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHU8</accession>
    <name>A0A8T0IHU8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G127800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009627">
        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039265">
        <property type="entry name" value="DIR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122:SF13">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_LIPID-TRANSFER PROTEIN_SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122">
        <property type="entry name" value="LIPID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035735016" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="11993" checksum="2F78F586026A4F70" modified="2022-10-12" version="1">MAMFKNGAGAAVALLVLLAMVFQSQAQTCPSATSMVSCQAAVTTVNTMPTQACCNKVKSVLDLGSVGPKCLCDAMTSPTAVAFKVIKSQAVLLPSKCAKLMGLQYIKGYNCAGAIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMS1</accession>
    <name>A0A8T0IMS1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G197300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="12866" checksum="79DB6948B7EABB5F" modified="2022-10-12" version="1">MGFGSPNTTENRSQLISNFTPNSNSSESAHRTILDMAKKKKTTFYPTFTWESHRRDLRNVGNSATTPVVDSSLDGFRSGQKERAEGEEKPLKAPRRDEDKSNGSDSASLLFDVVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMS7</accession>
    <name>A0A8T0IMS7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G254500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMS7"/>
    <dbReference type="OrthoDB" id="70250at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007720">
        <property type="entry name" value="PigQ/GPI1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47555">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL TRANSFERASE COMPONENT FAMILY PROTEIN / GPI1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47555:SF2">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL TRANSFERASE COMPONENT FAMILY PROTEIN _ GPI1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05024">
        <property type="entry name" value="Gpi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="523"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="553"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="721" mass="79882" checksum="4E7FDFF75C2F42F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPT1</accession>
    <name>A0A8T0IPT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DSBA-like thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G223000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPT1"/>
    <dbReference type="OrthoDB" id="37297at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875:SF2">
        <property type="entry name" value="ACR183CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33875">
        <property type="entry name" value="OS09G0542200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035793930" description="DSBA-like thioredoxin domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="DSBA-like thioredoxin" evidence="2">
        <location>
            <begin position="56"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="25208" checksum="64C6C0D2E1E87DF1" modified="2022-10-12" version="1">MGMGKSACSVERVIALGVLLTLVSGCWAQFTIPERYDGFVYNAKPEKGRGPVMWEVFVDPLCIDCKMGWPVVKQVAERYGSSVVVIVHPFPAPFHHNAYFAARALHVAQMANSSLVYPLMELIFANQESFLNPSTNHETPAHVVSRMISLASDLGIPSNTFEAGFNDSVTDQATRISFKYGCSRGVVGTPTYLVNGVNVVGADESWSADEWAKIFDPMVKATGFGMIYPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRC1</accession>
    <name>A0A8T0IRC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G032000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="345" mass="38609" checksum="962FFB6C495A6902" modified="2022-10-12" version="1">MFVFAIVTICGGFVMLFTWSLQMSGTFTGRNRRSAVRRRSGLGRQPDMEGLEEIGHSSEVANVIPSSTQGDIDLGDYLSAGDLPIDFTSVQRLKNICSERYERLVDETTTMAIEYLVFRKVTKDDLVKIDRSHRDLRIRIFYDFSMELLIVKLMVGKAHEWVSTLFAEHLREKVRGRCGDFYALCDMGAFRCTSAMGRVKEPDVALVPMNRENEADWPSCVIEVGVPESLAALKNDAHFWILHSGGLTRVVILIAVDPQTRTLTIERWGDEPPAYPSHVTGQVIRPRMAQCVTIDINGVIGAPLDVPSGLIFDVGHVPTGVLASDFSFDANELSALYTRFWGMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISQ7</accession>
    <name>A0A8T0ISQ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G059800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016621">
        <property type="entry name" value="UCP014543"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35732">
        <property type="entry name" value="OS10G0545100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35732:SF1">
        <property type="entry name" value="OS10G0545100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12646">
        <property type="entry name" value="DUF3783"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="25514" checksum="DBFE1B496F677E98" modified="2022-10-12" version="1">MSACKAFTVAVPVVSTGSSSVRGSCVRQRIGIPGQAGFPSFHYMSSRSGNSCVTKQWWKQCAPKASRMTRIMVSQEGVPQEILEDSKFVPINEDDPRFGPPAMMLLGFGDNDVATALEMIKDMGGDFMQVLVCTDEMMNGTLNEALNTTQPDLSQVKAATGMPPICFLSGLSGEELMMVVRAFPEAGLIGTAFAAHVPKNSNKPLRELTEEIMGDHERLVGCLRQTLARSMASDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWI2</accession>
    <name>A0A8T0IWI2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G214800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056511">
        <property type="entry name" value="IDM1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032308">
        <property type="entry name" value="TDBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025:SF2">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23209">
        <property type="entry name" value="IDM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16135">
        <property type="entry name" value="TDBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="356"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="9">
        <location>
            <begin position="741"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="54"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="132"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="197"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="78"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="96"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="199"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0588084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="906" mass="97891" checksum="9911660C24EA890A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXV9</accession>
    <name>A0A8T0IXV9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G213900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874:SF4">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874">
        <property type="entry name" value="RING FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="246" mass="27028" checksum="786DC504145E4A33" modified="2022-10-12" version="1">MVGIMGVVGAMAQTIQGALNWKTPKETDDAQRMENERLRMMIRLYEQAFQECHDQKAESGGVSVDRSMVVYEQLKQRVASPAFLEQLKPSQDLSDGASGLMLLRAEDGSYVKADMGDPSSWMFSKGSGSNGKMMKEVEDGLGSDGYVVVNVEDIVESIAGYVARYISSVPQAKNLTPTQLQEVMTEAFSNAERKGWLRSLYSTGRFLYTAGSWGVAALSIDKNPVVVRAASMAVWTSCWLILKLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZK9</accession>
    <name>A0A8T0IZK9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G260800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZK9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="122"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="438" mass="49990" checksum="A1C5013305902896" modified="2022-10-12" version="1">MGNTNSRVRHLPDVFCVCMGRSSKAGDVAGSAAEDAASSSSPHLPARNLVGEVGTESVEQQIKQSMLHWSQLTQFDSDCIDEEDVKADNMKVFLALQLDPSTRDFFNTFNYDTELWESVGSLEIGHKFAEGGQAELFHANVTWWKSEDNELDREHGREWVLKVFKKGTRLRHLQSQWPHGMLKFQEERVANWMSPTPKTYPRYFCNVQCGTLLGDGRFAFLMKKEHLDLRRLIDDKMKLISTNNCGPFSKEVAEKLMFDVGLGMSWLHSRGIVHRDLKASNVLVEVRDSGNIWCFVADYECSMGVVGTGPFRAPEILKACREKSVSKRPELFTMASDVYSYGMTCYEILTGRLPFDGHLGIDIMDAIITGKRPEVPEYVEEWVHKVLSDCWQHDPTKRPSFGEIMNLIFSNSVRIRGLVERGVTYHMDRMDWIKLEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J115</accession>
    <name>A0A8T0J115_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Essential protein Yae1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G276200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J115"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019191">
        <property type="entry name" value="Essential_protein_Yae1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028925">
        <property type="entry name" value="RRM_DME"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038881">
        <property type="entry name" value="Yae1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18829:SF0">
        <property type="entry name" value="PROTEIN YAE1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15628">
        <property type="entry name" value="RRM_DME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09811">
        <property type="entry name" value="Yae1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Essential protein Yae1 N-terminal" evidence="6">
        <location>
            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Demeter RRM-fold" evidence="7">
        <location>
            <begin position="253"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="188"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="202"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF09811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0588892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="337" mass="36520" checksum="F00380972BD37A40" modified="2022-10-12" version="1">MLDDDVWGSDSEVEGGRHVSSELEHEWQARQNQFHTLGYRDGVEAGKNSSVQEGFNLGYAEATVAGFNWGVARGVTSAFAALPAAVKERLVGAGEARGRLEALEASIRSYSSTDSLRSFYRDLGQTPEQGSQSFEEVRAHGLAALTEGPLDSGDEPGVVSMAGLNRLPESHSGGVWEAGHREEIEQATGLGRSAVEAGRGTVESTGSRQEQHVQQPGESSGEDRTAPLSSETPPAAGKSELEELEKRVRTELEVFADHASSIVPIDVRTLLWDLRRRFVYFGTSVTSIFKGYVCVRAFDQSTRQPKLLAARLHQSRAKIVAGRTLAKRGRRLGPSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J294</accession>
    <name>A0A8T0J294_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G003200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J294"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21491" checksum="05F8EFA476A1E578" modified="2022-10-12" version="1">MDSHHHRHPKRESVMKRKRRDSKRSKHRYESSSDAAAPSSSASSSSSSESSDSDSGSSQSGSNSDDHRSRRSSKRNHHHPNDHHPRRCEFFQIFLGLCFAITSAGEVLALVCHLVYSSWLFSFGFRGMRAQATVTLMTPNGLGNTDGKILRRRGRRQETFHSTAMGAQCWSSSPDCGDLQRCSRGLCNELHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J334</accession>
    <name>A0A8T0J334_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G060100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J334"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035734600" evidence="2">
        <location>
            <begin position="22"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="309" mass="33285" checksum="2BD4594387F038EA" modified="2022-10-12" version="1">MAIGAKHVLVVAIATLLLTYAAYQGKAASHGDGVSLAGRKGLSEPQRSETTPVVVEDSVTESDAAEDTTVQTFEGDTVKETSDEATEKTSEESTEETSVESLEETSEQTSEEPTEQTTEYSTEQNSEEPTEQTTEDSTEQALEDFKEEVSEFVSEEVPVEVSDEPVVEETEMTTEESTTVDGLWSSEDVQTQENVDFSAEMSEEASFDGKQMREMEESMSPQGALAPDMSPLPAPAVDLTPQAAPAPDISTATGPSTIIQNPDSSNYPKPLANPSVYLNEIAQDNYQAQRNEGWIQSCIAADNCGTPDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3M9</accession>
    <name>A0A8T0J3M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G107000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3M9"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044615">
        <property type="entry name" value="STR9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45508">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 9, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45508:SF1">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 9, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="85"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="28486" checksum="A3352F14D6DCCEA3" modified="2022-10-12" version="1">MATAMAACSSMAATATTFTASPAAPACQLRSRPCMLKAASYRWSGVHLKSFQRHLGTRSSLSEASQVTRAGVQYVDPEEAQKMVSEDGYQIIDIRDASQYDRAHITKSTHVPLFIANEDMDPGTLIKKFAHNSFAGAFYGLAFTKENDAFLPTIRKQFKKDDKILMVCQEGLRSGAAAEKLEEAGYENVAYLINGLQKVKPGTFEKEGPKDLCDAGKAGLVTIQQPFSVVLGTILIIALLFLQFFPDQSSQILKQFMTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4Q0</accession>
    <name>A0A8T0J4Q0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PSI-K</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G073100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4Q0"/>
    <dbReference type="OrthoDB" id="1904255at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.40">
        <property type="entry name" value="Chlorophyll a-b binding protein like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023618">
        <property type="entry name" value="PSI_PsaG/PsaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016370">
        <property type="entry name" value="PSI_PsaG/PsaK_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017493">
        <property type="entry name" value="PSI_PsaK_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03050">
        <property type="entry name" value="PS_I_psaK_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195:SF2">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT PSAK, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="194" mass="20327" checksum="2CB23E3FFF891BC6" modified="2022-10-12" version="1">MVHSGRVHGDWRSDSISRSLSHHRLGLSPTRASVSTSFYVCVALRLLHPRPNCVCWWRIITMAAMAATMSVTSASVRQFEGLKATTSFTKPVPSLAMRKTAGKGALGARCDYIGSSTNLIMVASTTLMLFAGRFGLAPSANRKATAGLKLVDRDSGLQTGDPAGFTATDTLACGAMGHVIGVGIVLGLKATGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J582</accession>
    <name>A0A8T0J582_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G061300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J582"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12404" checksum="B23C352978FCC2E2" modified="2022-10-12" version="1">MHPSFIVVVILLHRHIHQELKLNIVQQLGVKNKSATLITHIHCKMPTWGFLGHHFTLLGSLEQTHLHCLICLQQQISRGNVSRQLQWNHFLKEWFTGTVLPMEQNSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5A8</accession>
    <name>A0A8T0J5A8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G063900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="223" mass="24748" checksum="B28695298F5734C3" modified="2022-10-12" version="1">MDQRYQLAVELVMYPGHEVFQVAPDRNLETKVMDNVGNSSWCDENYMNFMKDICFSAANGLEMNSASSSKETFPFQPSALAGDDQSTEQLLPGCQEMVFPERLTLEQRYQEAKIPVMDVFSFDHLNPLDESRGGRTKGGFRPIICNRDEAEDSNSNAMSPLHTYLSSVSPEADLFVDFQVLEELPFGRFSGPAKFCTRPAGPGGITGSPFSEFSQKPLDSQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5Y4</accession>
    <name>A0A8T0J5Y4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G138100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5Y4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035836118" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="77" mass="8641" checksum="6D64528C3908C8DD" modified="2022-10-12" version="1">MRKVSAVRGAWCMMSFLLALLMHFSCVSLSVSVSIILCNLVYFCNLIFSAAEEDCKYLNMCVCILPSLNLMEIPILI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6Q6</accession>
    <name>A0A8T0J6Q6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="6">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G166300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6Q6"/>
    <dbReference type="OrthoDB" id="1911748at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043323">
        <property type="entry name" value="PIN4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45995">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="8">
        <location>
            <begin position="50"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="152" mass="15817" checksum="5B74716DCE66FFB6" modified="2022-10-12" version="1">MGKDSTANKGKAKDAGGKAKDAGGKGKGGGGEEKGGKGKGKAGKDDLGTCTYVKARHILCEKQGKINEAYKKLQDGWLDSGDKVPPAEFAKLAAEYSECPSGKKGGDLGWFPRGKMAGPFQEVAFNTPPGVCSGPFKSTHGYHIILSEGRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7L8</accession>
    <name>A0A8T0J7L8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G181200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7L8"/>
    <dbReference type="OrthoDB" id="1046782at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08619">
        <property type="entry name" value="PI-PLCXDc_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051057">
        <property type="entry name" value="PI-PLC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13593:SF113">
        <property type="entry name" value="SI:DKEY-266F7.9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="1">
        <location>
            <begin position="60"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="322" mass="36518" checksum="2396FC29883228D9" modified="2022-10-12" version="1">MGAQVSREKLVKGEKAQLKQKVAIPTEVAFPGCDFHHPNPKEWMGSLPLQNLRVRDVVWPGTHDSATNKIGLVGISRPFAQCQKLSVYDQLCIGVRCLDIRVQEERKVCHGPLKSYLVDVVINDLKKFLSETKSEFVILEIRTEFGYKDPPAFDKFLIEQLGEYLIPQDASFFGRPLSELLPKRVFCIWRPRQDPAPSPGSPLWSSAYLKDNWIDTDLPLTKFSGNITNLQNQPPNDQRTYFYRVENTATPQVTSAVLCVYPVTTRIRGYARLFLAEVFKKGIDNRLQIFSEDFVEPDFVDACIGVTMARNKLELIQPAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7X4</accession>
    <name>A0A8T0J7X4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">X8 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G217600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7X4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000008">
        <property type="entry name" value="Glucan endo-1,3-beta-glucosidase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044965">
        <property type="entry name" value="Glyco_hydro_17_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012946">
        <property type="entry name" value="X8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32227">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00768">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00587">
        <property type="entry name" value="GLYCOSYL_HYDROL_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035810824" description="X8 domain-containing protein" evidence="8">
        <location>
            <begin position="20"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="X8" evidence="9">
        <location>
            <begin position="368"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0592004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="53238" checksum="26C7767E86D60DA9" modified="2022-10-12" version="1">MARVVALVALVILLMVASAEIHVSALGVNWGNHAFNPLPPKDVVKLMQINGIKKAKIFDADYDMIRSMAGSGIEVMVAAPNNMLYSLANDPNAATAWVKQNVTQFLFQGGVDIKWVAVGNEPFLTAYNNSYLNTTYPALRNIQTALDQAGHSEVRAIIPFNADVLTDSPKPSGSRFKPEYISQIQPMLEIFNRTGAPFSVNLYPYISKYQNPDFPLDYAFFSGTTSPNVDGTIVYQNALDASLDGLITALGAAGYPNMAVMLGEIGWPTDGAPFATVELAGRYMQDMITHLQSGVGTPLRPNSFTEFYLFGLLDENWKSILPGPFERSWGVFYYDGIPKYPLNLNSGLTNLAATTLKALDYPPYMKAQFCVLNDAAVDKTNLTQNVQYACERSDCTALNPGSTCSMLTENASYAFNSYYQSQNQDMNACDFQGFAKVVTTNPSQGLCRFPLSLVPTAKSTSGASTLRLDSGVLALTLAASLVSALWTMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J802</accession>
    <name>A0A8T0J802_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G150200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J802"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8787" checksum="B44ABB73B4AFF388" modified="2022-10-12" version="1">MISPPDSRQDQTAIKPETAPASGKLCSHTYALHTTRHKLHHRETPAPMINKPKQKRERETTDRRNGGMSKMQEGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDZ7</accession>
    <name>A0A8T0JDZ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G303200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SURF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDZ7"/>
    <dbReference type="OrthoDB" id="444809at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029190">
        <property type="entry name" value="Rrp14/SURF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029188">
        <property type="entry name" value="Rrp14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007019">
        <property type="entry name" value="SURF6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14369:SF0">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15459">
        <property type="entry name" value="RRP14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04935">
        <property type="entry name" value="SURF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal RNA-processing protein 14 N-terminal" evidence="6">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA-processing protein 14/surfeit locus protein 6 C-terminal" evidence="5">
        <location>
            <begin position="147"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="140"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="152"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="244"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="268"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF15459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0593068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="355" mass="39876" checksum="171F4FEC2CD77A61" modified="2022-10-12" version="1">MAMAMAMDFSMDASSAHDAALQDAIHQHAVFFDRLVEMIPANIYVAKENPTDQWVHGMSKKARAESKRKTKLNLKKAKRARLDPENARTTLEVIQQQEKTKDTPTGSSVAAGGGADKPRTVTYEELRDRLHKRIEMLRAKRHADQAASTAKVAKEWQNQKKNDSLKRNRKSKALDPDASTDGETTAPAAKRPKLDAKQAPSGIVEDGLEFGRVKMGIGADLGHSKKKKPSKEKLLEQAKTLQEQMHDPEKGQEVASKHAWSAAVSRAAGEKVLDDPKLLKKSIKREEGIRNKSAKKWQERKEMEKKGQQKKQDTRKEHIQQRATEKKERSIAKREKKLARPGFEGRKQGFINKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G2G8</accession>
    <name>A0A8T0G2G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G002700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G2G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008889">
        <property type="entry name" value="VQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039607">
        <property type="entry name" value="VQ_8/17/18/20/21/25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33143">
        <property type="entry name" value="F16F4.1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33143:SF6">
        <property type="entry name" value="OS08G0102900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05678">
        <property type="entry name" value="VQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VQ" evidence="2">
        <location>
            <begin position="80"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="303" mass="33022" checksum="68E873E23CAEE62A" modified="2022-10-12" version="1">MSPTSPVYYPKVEEDLQNGGHSSGLKLPSTFPFGIRTKPPKHPEKISVSALKVCNDSHRIRKPPRPLPQVQYRAPLIIHTYSPKVIHTDPDDFMSLVQQLTGSSDTRLRLKRKPSKKSSKRASSPKPPPVPEPKQPQGEDLNCGSPSSSQDSGVFASTSGSVDPKTGKQSNSPRGPLSNFEFDNTFTEVKSEPAQFDNSFNFYTGLKPLPKPASVETGYSLYHGIDINSPLPSPGFISPGWLPELSPGTAAWSQAFLDCLNGSPRLAEQPPLQRQKAYSSGHSPKPSEGTMVALESIQAFMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6M2</accession>
    <name>A0A8T0G6M2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G110100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6M2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000174">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="180"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="562"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="868"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="595"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="627"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="868"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="900"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="265"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="983" mass="108975" checksum="B80A31DBF9B3C8C0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8I9</accession>
    <name>A0A8T0G8I9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G146400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8I9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000019">
        <property type="entry name" value="PQ-loop repeat family protein / transmembrane family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000012">
        <property type="entry name" value="Vacuolar membrane PQ loop repeat protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051415">
        <property type="entry name" value="LAAT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006603">
        <property type="entry name" value="PQ-loop_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201:SF44">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16201">
        <property type="entry name" value="SEVEN TRANSMEMBRANE PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04193">
        <property type="entry name" value="PQ-loop"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00679">
        <property type="entry name" value="CTNS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="345"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="143"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="162"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0555125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="427" mass="46823" checksum="25CD1965451A90DA" modified="2022-10-12" version="1">MEGVFGPLPQCPAEKPCLKWVQIYLLDCVCSTRDRFSLALGLMSVLSWGVAEVPQILTNFREKSTEGVSLLFLMTWVVGDVFNLLGCYLEPATLPTQFYMATLYTLTTIILVLQTIYYDHIVRWWANDRVEVEDLFPEVQKTDMEAQKPISIPESANGGPESISPQSSQPTSIRVPHHQHIHGSSPGSRDHLYIQSARSLASSYAQPIGSYNVPGSRGSTGGHHNSYLLTREDSEPPPLVGSRPRRLSTSSLSTSAIRTVASGVLLVGSLGISLYTSPRIASGGSTVGTTNAGRDNLRLGDPFLGEEPSPLGEVFGWIMACIYMGGRLPQIWLNIKRGTVEGLNPLMFVFALLGNLTYVGSILVRSMEWAQLKPNLAWLVDAGVCVILDIFVSFQKLFIFVSSCHVFQTLLFISKNHISTLSLTGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA26</accession>
    <name>A0A8T0GA26_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G161200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA26"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="24479" checksum="16A5D193A328519B" modified="2022-10-12" version="1" fragment="single">IHTFSALSRDGEAHLRIRCARPPGRGGGRRRRWSHQRLLRGGPEERPPLQWLGLQGPVDGDVRRLRLHGLPRCGRHQQPAGHRHHPRVRWRELPGAEHAGPVPGQVQLRQGRSGATPHAPQGVGGDHGAEGRGARRVRGHGREAVRGEAEDGRLLPVPGGSGALPAERGQRARGDGVGAERAEPRSAADGVGAVRREPGDQGRGAVEGVRDQGRHDEDDQEGVHAGDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCR0</accession>
    <name>A0A8T0GCR0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribosomal protein L37</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G041600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.30:FF:000001">
        <property type="entry name" value="Ribosomal protein L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_eL37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_eL37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_eL37/eL43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_eL37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10768:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN L37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 9" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0556297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="10663" checksum="6936E38501729CB6" modified="2022-10-12" version="1">MTKGTGSFGKRRNKSHTLCRRCGRRSFHIQKSRCSACAYPAARVRSYNWSVKAIRRKTTGTGRMRHLRHLPRRFSNNFREGTQAAPRKTAAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDZ4</accession>
    <name>A0A8T0GDZ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G113800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDZ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15497" checksum="B59951D029CF7B8A" modified="2022-10-12" version="1">MITGNVDEDLRICCKVQFGSLMALFFSGGSLSCFLGVTLVALSYNTLRKLKGLLFTCSYCEHVALVSLYWLPHLRFCVLMGHLWTVQVNPLWHLSAQWQLRVRKSISIREHSIVSFLNTSILKIFERLQNVSFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE50</accession>
    <name>A0A8T0GE50_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Squalene monooxygenase</fullName>
            <ecNumber evidence="5 12">1.14.14.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_11G050100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>squalene + reduced [NADPH--hemoprotein reductase] + O2 = (S)-2,3-epoxysqualene + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25282"/>
            <dbReference type="Rhea" id="RHEA-COMP:11964"/>
            <dbReference type="Rhea" id="RHEA-COMP:11965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:15441"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="1.14.14.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Membrane</location>
            <topology evidence="2 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the squalene monooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.17" evidence="5 12"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004506">
        <property type="term" value="F:squalene monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009725">
        <property type="term" value="P:response to hormone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000074">
        <property type="entry name" value="Squalene monooxygenase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013698">
        <property type="entry name" value="Squalene_epoxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040125">
        <property type="entry name" value="Squalene_monox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10835:SF0">
        <property type="entry name" value="SQUALENE MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08491">
        <property type="entry name" value="SE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0274">FAD</keyword>
    <keyword evidence="6 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Squalene epoxidase" evidence="13">
        <location>
            <begin position="216"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0556389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="57320" checksum="67D3B98A21955BEB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFZ3</accession>
    <name>A0A8T0GFZ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G101300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1300.10:FF:000004">
        <property type="entry name" value="Outer envelope protein 64, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006169">
        <property type="entry name" value="PRK08310.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="4">
        <location>
            <begin position="59"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="475"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="543"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="592" mass="64171" checksum="0E4BF156308FB593" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJF6</accession>
    <name>A0A8T0GJF6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G081500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJF6"/>
    <dbReference type="OrthoDB" id="1045822at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="234" mass="25626" checksum="151A70F93F7EE2FB" modified="2022-10-12" version="1">MASGLRSGDQSSSSPPGSSTSPAPLRHASSSGSKSVRSSQGRASNSEKTPLLPRIAKAPERVTGTQERGNYGAMQDGGKAKLPDYEIPIWQNQPMWSTGLFDCCADVPMCCFTIFFPCFAFGRNAEALDGTKNSCWTTAAVWWALQHTIALGCLYSASYRGKLRSKYNIPEGPVPDSVIHCLCWPCAFCQEHREIHYRSFGPESWGQTITVAPVQQEFQSSHTKSSKKAKPLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJK7</accession>
    <name>A0A8T0GJK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7748 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G118400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056650">
        <property type="entry name" value="DUF7748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468:SF1">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24928">
        <property type="entry name" value="DUF7748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7748" evidence="1">
        <location>
            <begin position="6"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="11778" checksum="7E21C18DCF6C2CA8" modified="2022-10-12" version="1">MAATIQTKVFNGTDKALELKEGNGGNYRYLDTIPKNESSKIDCDVNATYREYWVGTAAGIAEVVITSDDCAECSDIRIVPAGVGRSKLEKTLRSPAATQAESTSGRTCVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK76</accession>
    <name>A0A8T0GK76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G102500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6562" checksum="042D16D5106CE9E5" modified="2022-10-12" version="1">MLWTSMLMSTGPAMAVGKQARSFIQERDFCFRVLRLNEEEGEFNCQGFVTGQKGDVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GL47</accession>
    <name>A0A8T0GL47_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G068100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GL47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="840" mass="94815" checksum="CF4BDBD465C066D8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLX6</accession>
    <name>A0A8T0GLX6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aconitate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G189300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLX6"/>
    <dbReference type="OrthoDB" id="2224430at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006101">
        <property type="term" value="P:citrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01586">
        <property type="entry name" value="AcnA_IRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.19.10:FF:000001">
        <property type="entry name" value="Aconitate hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000002">
        <property type="entry name" value="Aconitate hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.499.10:FF:000005">
        <property type="entry name" value="cytoplasmic aconitate hydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="entry name" value="Aconitase, domain 3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="entry name" value="Aconitase, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006757">
        <property type="entry name" value="PRK09277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009520">
        <property type="entry name" value="PRK12881.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="Aconitase iron-sulfur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52016">
        <property type="entry name" value="LeuD/IlvD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha" evidence="10">
        <location>
            <begin position="170"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase A/isopropylmalate dehydratase small subunit swivel" evidence="11">
        <location>
            <begin position="802"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0560551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1002" mass="108992" checksum="204B7B0BE231A6C4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM30</accession>
    <name>A0A8T0GM30_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF962 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G093400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM30"/>
    <dbReference type="OrthoDB" id="5511466at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009305">
        <property type="entry name" value="Mpo1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34205:SF2">
        <property type="entry name" value="DUF962 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34205">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06127">
        <property type="entry name" value="Mpo1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="117" mass="14095" checksum="3F803BF52084BBF6" modified="2022-10-12" version="1">MSVDKMHFRNFEEFWPFYVNQHTKASTRRWHFCATGFATLFFIAAIAIKWWLLFFAPLFGYGFAWYSHFFVEGNRPASFGHPIWSFICDYKMFILMLTGRMDREIKRLGKRPMLQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNX5</accession>
    <name>A0A8T0GNX5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G048700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11948" checksum="39B238386BBA64F6" modified="2022-10-12" version="1">MQSHHLKQHSVSRYSTLHLIIDAIVSATGRWNIHRQDCRNNHRGEFKSERANIFLVYGTLLENWRLNNIPEEKDVIPIILKVNPKSQQKLETETYQRTLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPY2</accession>
    <name>A0A8T0GPY2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G172800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPY2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="14093" checksum="2CEF3D13BC6DCC33" modified="2022-10-12" version="1">MLSIFSELKYSKLLPLSRPRSALSTFPRIYSHLPEIQTSEEITDRRHGQLKISYHKLELQIEYQGFQKGLSDGRLDRIKISQSLLPPQHRVDLRRSAMQDIVDKRTREKTRSLNFTRCAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQL0</accession>
    <name>A0A8T0GQL0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">C2 NT-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G145100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQL0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019448">
        <property type="entry name" value="NT-C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021827">
        <property type="entry name" value="Nup186/Nup192/Nup205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31344:SF11">
        <property type="entry name" value="NUCLEOLAR PROTEIN GAR2-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10358">
        <property type="entry name" value="NT-C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51840">
        <property type="entry name" value="C2_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2 NT-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1116"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="407"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="478"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1164" mass="126337" checksum="249186665307C330" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS97</accession>
    <name>A0A8T0GS97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G047100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11798" checksum="9613C687984D5D3B" modified="2022-10-12" version="1">MKGRAVSRGWGMQWMPGRVKTIMLRCAGRGGAEGRVFLYDRASALILVLYITIGITLEGKGASVSMLENDLFSDVAAASCNLWQPLVGCNIISYLMQTWVLLQCHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUZ9</accession>
    <name>A0A8T0GUZ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G010300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11207" checksum="F322431513C1B851" modified="2022-10-12" version="1">MKIICGSPVCCLNLETPNGINSTFEKAPVPNHVISRFPPFGKRSRTSKEIKACETRAQLHSNRTYNLSSNPEACRTKSLSFTAEMPSNYNIVHIIHTEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXA5</accession>
    <name>A0A8T0GXA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G071900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039218">
        <property type="entry name" value="REM_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM-LIKE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674:SF25">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR VRN1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0561542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="23976" checksum="438DCABFCC184825" modified="2022-10-12" version="1">MEAFEDALTPYVESGVTYFSTLITGSLSFDVLEIPAHFTAKTRWPGGRNCTIVTSIAGQREWPLKVLRGEGGDARSIGTEWREFLEDQGIGVGHFIIFEAVDERTLVADVHHPPGLQPAFVKIIRPSHLRIHKLDIPTKFWRRLGSGNFDGFKYKLFGDKSTVRVSSAVTANAAQTQCHFTVGWREFCKENKVKCGDKMTFTQVDTYSFRVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY11</accession>
    <name>A0A8T0GY11_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G032100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY11"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052370">
        <property type="entry name" value="Meta-cleavage_hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43139:SF62">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43139">
        <property type="entry name" value="SI:DKEY-122A22.2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="66"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="318" mass="35651" checksum="2247E7E09DB82396" modified="2022-10-12" version="1">MGKGTSCFGLSMVAMKMSYVKQQQFRAHGLRSELVKVDDGATVIRCWVPWQQPEGGVWSAGVADKPAVLFLHDFVADGTVNWEKQIGAFTKEFNVYVPDLVFFGGSETRKEERTEAFQAHCMVKMLHALEVYNEVTVVGAGYGGAVAFWMAHLYPKLIERVVFVATGMHMTPTSQKPLLAEFEYDHISELLLPTTAKGLRNFASVATYKRVHRLPKFMCTDILDVFFDEHRYEKVELLSKMVTGSRGEPPLPLLTQEKSLIIWGAEDQITSLDLGLKLKLHLGNSTNLVVMNKCGHFPQIENPGSFNRILSNFLKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYQ4</accession>
    <name>A0A8T0GYQ4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G151400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYQ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19501">
        <property type="entry name" value="RecA-like_FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000083">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000352">
        <property type="entry name" value="ATP-dependent zinc metalloprotease FTSH 7, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF111">
        <property type="entry name" value="INACTIVE ATP-DEPENDENT ZINC METALLOPROTEASE FTSHI 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="315"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="12">
        <location>
            <begin position="494"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="966"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0564941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1002" mass="110136" checksum="BC3982E17E63D419" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYU6</accession>
    <name>A0A8T0GYU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G046300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="9113" checksum="EE032A29F4BE67EC" modified="2022-10-12" version="1">MLLRCCAQGMCWIHVNGITASFGWAEELLAGTGYRVSQIFFWELSYCDCDLCGSFSWFHFKEIQNLSAWQLISTCMIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ16</accession>
    <name>A0A8T0GZ16_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G052100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ16"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004462">
        <property type="term" value="F:lactoylglutathione lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="entry name" value="2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018146">
        <property type="entry name" value="Glyoxalase_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC_core"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46036">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46036:SF5">
        <property type="entry name" value="LACTOYLGLUTATHIONE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00934">
        <property type="entry name" value="GLYOXALASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035946978" description="VOC domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="3">
        <location>
            <begin position="99"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16755" checksum="91C4ED2E86856F47" modified="2022-10-12" version="1">MPEAMVMTMAMAKILIVPVASAASISTRAAAPRLTLRLPRPGLLCPALPPLSRRHIPVLPRLTQVQQSRGPAIMASAASAETATNEENILEFVKNDTRRMLHVVYRVGDLDKTIKFYTECLGMKLLRRRDIPEEKYTNAFWVMVLKIPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZK5</accession>
    <name>A0A8T0GZK5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G073800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZK5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05282">
        <property type="entry name" value="ETR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF2">
        <property type="entry name" value="ZN2+-BINDING DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="15"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="331" mass="35215" checksum="9299DBB14E47D560" modified="2022-10-12" version="1">MANVAIVQDGYDAKDPLSTLKLVTKPIPKPAPGQVVVHIILRPVNPTDLITLRTGAIANGGVAGSEGYGIVYEVGEGVTKLHKGQRVIPFTAEGSQSGTGSFQKYVCIDAHFVWPVPDYISDEVAAQFVINPWTSYSLLKDLQVPKGQYMIQSAAGSVLGRQVISLAKHWGIKSINVVRRSEQKAELKALGADEVIVSSEEDIVARAKEITGGKGVYGALDPVCGTTTGTLASCVRNGGQIFVYGVLSGFSATVSVVDLFRDVSVTGWGLYTKATNDPKKCLALATEVAPLVRDGIIPVAEVEKYDLTDFKKAMVKADEPARSVRVLLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H092</accession>
    <name>A0A8T0H092_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G093800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H092"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="4307" checksum="7039BD6FF12E99F1" modified="2022-10-12" version="1">MANCMHFALCHFLCNFHILYICSDHQRQTSRSDFES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2M5</accession>
    <name>A0A8T0H2M5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L18a-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G154300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2M5"/>
    <dbReference type="OrthoDB" id="1916999at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044804">
        <property type="entry name" value="Ribosomal_eL20z-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46631">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46631:SF4">
        <property type="entry name" value="OS06G0359400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="154" mass="17041" checksum="3B8E25C6BE7AF633" modified="2022-10-12" version="1">MGFEKGGSYGTFEGQQGFPQPSAPPLAGTYSNGGQQYPIVPGYPVLENYPGSHRGSGSYQAAQYPGPQAQTCYHECHEVTYHPRRLPFCGLGFGWFLFIMGFFIAVFPWYIGAGIFLFVRHDYRERTGLMACTIAALVLLFVGGVGFHVHMLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3U5</accession>
    <name>A0A8T0H3U5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SAM-dependent methyltransferase TRM5/TYW2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G028800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36635"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="Rhea" id="RHEA-COMP:10379"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73543"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.1.1.282"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>4-demethylwyosine(37) in tRNA(Phe) + S-adenosyl-L-methionine = 4-demethyl-7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + S-methyl-5'-thioadenosine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36355"/>
            <dbReference type="Rhea" id="RHEA-COMP:10164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10378"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64315"/>
            <dbReference type="ChEBI" id="CHEBI:73550"/>
            <dbReference type="EC" id="2.5.1.114"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; wybutosine-tRNA(Phe) biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3U5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102522">
        <property type="term" value="F:tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031591">
        <property type="term" value="P:wybutosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000131">
        <property type="entry name" value="tRNA wybutosine-synthesizing protein 2/3/4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.110">
        <property type="entry name" value="Met-10+ protein-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1960.10">
        <property type="entry name" value="tRNA wybutosine-synthesizing-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056743">
        <property type="entry name" value="TRM5-TYW2-like_MTfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056744">
        <property type="entry name" value="TRM5/TYW2-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003827">
        <property type="entry name" value="tRNA_yW-synthesising"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036602">
        <property type="entry name" value="tRNA_yW-synthesising-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245">
        <property type="entry name" value="TRNA METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23245:SF25">
        <property type="entry name" value="TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="TRM5-TYW2_MTfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25133">
        <property type="entry name" value="TYW2_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02676">
        <property type="entry name" value="TYW3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111278">
        <property type="entry name" value="SSo0622-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase TRM5/TYW2-type" evidence="9">
        <location>
            <begin position="855"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="306"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="335"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0565980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1113" mass="121713" checksum="3194FF4044A089E7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4M0</accession>
    <name>A0A8T0H4M0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G178400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GEM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4M0"/>
    <dbReference type="OrthoDB" id="732558at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd13222">
        <property type="entry name" value="PH-GRAM_GEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037848">
        <property type="entry name" value="GEM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31969">
        <property type="entry name" value="GEM-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRAM" evidence="3">
        <location>
            <begin position="239"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="34"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="409"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0565279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="421" mass="43887" checksum="EED630423FABDBC0" modified="2022-10-12" version="1">MNQGNYNQGPVPTYDATHNDDEPLFTSPPEERQPSMSRPPQQQSTPSTFGAPPMGEPSVPSAHPDNLTAATYTAGGSPGASGAPVQMGGPQLGSPGGTSLGRSQSSSVGAFEKPMGGGLRRQSSGAYDASTATKTDKGFFGGATQHTAEQQAAPQPGVAGPTPVGVKPGSPYVQTQEVPSSGTSPMNQIVGNFNKYMAKAELLAGNIWSHMNTGASPLDAARGRVSQGIKLVQEGGFEGLYKASFGPMADGEQLRKTYACYLSTSTGPVAGTLYITNLKFAFCSDRPLAYAPAANQTAWSYYKMVVPLEKVKEVIPSFNETKPAEKYIQALTNDGHDFWFMGFVNYDKAVNNMQLALKNIGVVDPNGGLKAPWAGMKVPGLKRTGSGVAPQSTTSVPAGHVPTAGGPSPNYPPSQAPPPTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5D1</accession>
    <name>A0A8T0H5D1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G028300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5D1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035887257" evidence="1">
        <location>
            <begin position="18"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5562" checksum="4B8E58303E69CB9E" modified="2022-10-12" version="1">MIRELLRLAWRVRHLFASCLCDVRTDCEACSAWVVNGLGGLREKGDGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6C2</accession>
    <name>A0A8T0H6C2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G024600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6C2"/>
    <dbReference type="OrthoDB" id="654824at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004864">
        <property type="entry name" value="LEA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044839">
        <property type="entry name" value="NDR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234:SF2">
        <property type="entry name" value="OS05G0199100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03168">
        <property type="entry name" value="LEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Late embryogenesis abundant protein LEA-2 subgroup" evidence="5">
        <location>
            <begin position="136"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="30125" checksum="6CF4BB57F87C4F5F" modified="2022-10-12" version="1">MSSSGRNRKEIFLHGDEDTNRKKIVIEDDGKPKKIVFEENGKVTKTIFEGDSDDENPRQTIIIREGGGDKPKGWGVVKMALAAIPWVAGAGFLVYQNRPQDPILDIKNITLSGFDLHLSKESMLLAVLDVDLTLFVRIVNPNIAPITFDTTILDIYYKGSILGQAKLYPGDQAARSEQMLELPCKLNGLEATHHLQDLLGDVAKRVMVLHARATINGNIAVLRYRHHFEVYLQSEIKVDPIFLDVIDQRHRADLYIEGVEVPKLMDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6D9</accession>
    <name>A0A8T0H6D9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G055800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6D9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8713" checksum="82E378A256ED2A6D" modified="2022-10-12" version="1">MGASGGPPGMMHNGWCWPVGYGDLFSESSMLAVGVCWIQVARVAFSMQLWEIFILVLRPLRGDFTSLVFTKEEEVGGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7W5</accession>
    <name>A0A8T0H7W5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">rRNA biogenesis protein RRP36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G065200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Associates with 90S and pre-40S pre-ribosomal particles.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the RRP36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7W5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030686">
        <property type="term" value="C:90S preribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009292">
        <property type="entry name" value="RRP36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21738:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06102">
        <property type="entry name" value="RRP36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="65"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="355" mass="41062" checksum="573358B3F6BF46A9" modified="2022-10-12" version="1">MGRKKEEEESEHEESDEEQASSDMDESGSGSEDDESESGSGSGTDSEEEELQGQVADVPFEVLQQARSSGQVTSFSRAKKELETKRANKNRPMEITSKKPVPRFREVIQAPKREVRDPRFESLCGKFDESRFKKSYSFIYDEELPAERQRLKKELAKGSGDTEEAKKRLEWIDRELREEQQRRKRAEAAAQHGSKEREAVKQGKKPFYPKKSEQKKEELVEKYQELKVLLYPISFSKIVAESLNCAYCCRQTCGLMVEGVLSCRRVESSTNLWKSGGKRIPPRIIDLYHIDGHKCNIPLAFNNGLPEVLWIFVILKKLGFTRNEGSCWHAEWTAREAENDLRFYMKMPFRETRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H849</accession>
    <name>A0A8T0H849_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G063100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H849"/>
    <dbReference type="OrthoDB" id="1930404at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34564">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34564:SF3">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274475" evidence="3">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="95"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="27"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17527" checksum="C6F675F4DD397458" modified="2022-10-12" version="1">MSRPMALGLVLLVLILTSQSDWKQDTRTELEENASTVTKQEDALTNRDTVKQEIILMQEKEIHHLKLHVKSLEEKLKLCQCEVPDNSTIKVPVSEQADTQLSSKELVDPVSEKATKLRGSVRPSRGLDLSERPSELPVLDDALDLADDDEEKIGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H861</accession>
    <name>A0A8T0H861_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G146400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H861"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="167" mass="19392" checksum="0CFF0B43FF4F1985" modified="2022-10-12" version="1">MAAGEGRNMGTKRKASEALPCIVIRQVKAARPIKVAEGKGVVLSKEDQEITERFEENLMELYDPVFSEAYSGGLEQFQHFDVQQKMPLYCEAESLVMCDEYTEDTEDHDEYFDEDSDFDTIINVLLEEIPARWRSGEITDEEAFEYYRELGNLMSNEDDRESFSFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA04</accession>
    <name>A0A8T0HA04_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G145000</name>
        <name evidence="2" type="ORF">KC19_7G117100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11316" checksum="2A4E84447C38222E" modified="2022-10-12" version="1">MVVNNRISVMFYPMKTITWNSLRTCRSETHQLITSLLTGISLPYCRNNVGSMRFHFHALARGLGSYSTTSSLSFPAELCRGNVGLQHCQPRVTNLSRQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB27</accession>
    <name>A0A8T0HB27_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G130900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14365" checksum="4DA6A336710CDFA2" modified="2022-10-12" version="1">MPFKVLTKLSTLDAAGSLRKELQVHLHLSELEKALDPDSRFSKCIGESGSRYKGLYLVSTPETPGSTKNCIKTWFPGTFPNPRGEEVYMFMGRNYSIQKSTMPKKLKALASCCKETLDSGSPLFDPSVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB96</accession>
    <name>A0A8T0HB96_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G151800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044841">
        <property type="entry name" value="LUX/BOA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442:SF29">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="281"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="226"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="412"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="103"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="128"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0567658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="463" mass="49160" checksum="EA9F3FD034F70679" modified="2022-10-12" version="1">MHACERPRIGMTMKDDDRGLEWKHSLPTSEDLTPLSKSFLSPAFQSVFNIKPEPPKAAGDVSRESRASFLELRSQRSAVSSFDPFPLFKERKDTGGYGQPVEARGDAEAREGDSRGRAFSDFVGEGRGGARAEVRRESREAEEPEVGLGLGIGSGGGGAGGGGGGGSERGGVAEKQGHGGQVASLFRVGSDPTGYNASEGRSEQSPGGLPFMMNGLGYGSFERRAESSSYSGRGDEKVGGSAKNARKLADSDFEDTDSAGGPVNSNEEPNARTLKRPRLVWTPQLHKRFVDAVGHLGIKNAVPKTIMQLMNVEGLTRENVASHLQKYRLYLKRLQGLPADGAAAAAAGDQLFASTPLPPNLGLHYMGSQRDDVGPQSFPSGGVAMPFGGMGGRGPLGPAHFSAYEPIPYGGMNRAFMQRPSMKDRTEESSESESQNHQQQSGSGNQASSPPKRLLSLFPTSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCM5</accession>
    <name>A0A8T0HCM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histidine kinase/HSP90-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G170400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCM5"/>
    <dbReference type="OrthoDB" id="28737at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000012">
        <property type="entry name" value="Heat shock cognate protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.790:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.80:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11260:FF:000001">
        <property type="entry name" value="Heat shock protein 90 alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="entry name" value="Heat shock protein 90, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003555">
        <property type="entry name" value="PRK05218.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="HSP90 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase/HSP90-like ATPase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="220"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="678"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="236"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="678"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="108"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="128"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR002583-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0567899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="706" mass="81136" checksum="11374BC077619265" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD30</accession>
    <name>A0A8T0HD30_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Small ribosomal subunit protein uS2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G110800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 7">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD30"/>
    <dbReference type="OrthoDB" id="414863at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000028">
        <property type="term" value="P:ribosomal small subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000017">
        <property type="entry name" value="40S ribosomal protein SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03015">
        <property type="entry name" value="Ribosomal_S2_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_uS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_uS2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027498">
        <property type="entry name" value="Ribosomal_uS2_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_uS2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_uS2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN SA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="Ribosomal protein S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0569716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="300" mass="32375" checksum="4AB2BBF495B19ACA" modified="2022-10-12" version="1">MKESDVQMMLAADVHLGTKNCDFQMERYVWKRRNDGIFIINVGKTYEKLELAARVIAAIENPQDIIVQSARPYGQRAVLKFAQYTGCQAIAGRHTPGTFTNQLQNTFCEPRLLILTDPRTDHQPIMEAALGNIPVIAFCDTDSPMRYVDIAIPANNKGKHSIGALFWLLARMVLQMRGTISAAQPWDVMVDLFFYREPEESKERDEEEGAAPEFAAVEYAAPALGLGGEQWGPEAAEAGQWEQPEAAAAAGVPAAAPAAGWDVGAAPAVPAGWDTAAAAAAPAGWEGTAPPAAQWEPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE51</accession>
    <name>A0A8T0HE51_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G041000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035909808" evidence="2">
        <location>
            <begin position="27"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11142" checksum="C7FE29F6C62E0334" modified="2022-10-12" version="1">MAGSGRRMAWFCCVVLLLVVVDGAVAFERRVDWDQARVVGSTQELYLRGNTVTTPESVSTEAVKSYDTFDEFQRRELEDSGYSTNPADPNCDNDPTLCDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEW0</accession>
    <name>A0A8T0HEW0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G143200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021319">
        <property type="entry name" value="DUF2921"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33389">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE (DUF2921)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33389:SF18">
        <property type="entry name" value="OS01G0677900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11145">
        <property type="entry name" value="DUF2921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035868734" description="RING-type E3 ubiquitin transferase" evidence="11">
        <location>
            <begin position="18"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="SWEET-like" evidence="12">
        <location>
            <begin position="358"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF11145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0570163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="715" mass="81078" checksum="7A9CBA4DA9774ABB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFD6</accession>
    <name>A0A8T0HFD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein FAM91A1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G130800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM91 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFD6"/>
    <dbReference type="OrthoDB" id="275996at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039199">
        <property type="entry name" value="FAM91"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028097">
        <property type="entry name" value="FAM91_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028091">
        <property type="entry name" value="FAM91_N_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28441">
        <property type="entry name" value="PROTEIN FAM91A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28441:SF2">
        <property type="entry name" value="PROTEIN FAM91A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14648">
        <property type="entry name" value="FAM91_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14647">
        <property type="entry name" value="FAM91_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM91 N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="FAM91 C-terminal" evidence="3">
        <location>
            <begin position="362"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="FAM91 C-terminal" evidence="3">
        <location>
            <begin position="529"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="909" mass="100410" checksum="D426C566A60FC2AD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFT0</accession>
    <name>A0A8T0HFT0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G165900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant LTP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFT0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043325">
        <property type="entry name" value="LTSS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000528">
        <property type="entry name" value="Plant_nsLTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33044">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR/LIPID-TRANSFER PROTEIN/SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00382">
        <property type="entry name" value="LIPIDTRNSFER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00499">
        <property type="entry name" value="AAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274500" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="17491" checksum="2DB4095B12502036" modified="2022-10-12" version="1">MARSSSVAVAIVMLAMLVAGAASAPSPPNCDSAANALMPCYSYVTGPEAKPPTECCGGLRDLNTNSPACLCQLISQLNSGAASQPSLNITKAYNLPEDCAIALKTSDCPALANLPLAPPSGATTPSTAVPTTASQGPAAAGPETSLVPGNDVPRILPTGTWVMVVAAAVLGVQALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJU1</accession>
    <name>A0A8T0HJU1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G209200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15385" checksum="A4F59F86C5668E3E" modified="2022-10-12" version="1">MWSAVSVTECSFVDGIRRGLQHNDSGDGFFFSFVLLCFVLKTSKELVVQITRWSKGWSMWECETMKSMGEMAYAIAVKCGVRGEASLQVSDDKAGVAGNPFLRITPFLGGHRLQSTLNVSRSKQQRLTPELLRAQCTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMZ7</accession>
    <name>A0A8T0HMZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG076000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10315" checksum="121EA11D88E60AE9" modified="2022-10-12" version="1" fragment="single">MCDNRMIFHNGRGVFLPLRGEADVLFLCAECTDRVFSENRTLTHVPSYLDATFYYLAPLLFVNPKVVICWSSCKIDYRRIVHEITSPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN91</accession>
    <name>A0A8T0HN91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG082900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="16277" checksum="36A2A3CCF41F9E6B" modified="2022-10-12" version="1">MSRHPEHILLHIFTHISSGMCAVEASGPMDGPLCSPTIPRENKILEVNIHGIHTSRCVLGLRCGELQCFFLHPLRELCNYSPDHFVIPHLLNIFLRQAPPRPRHGSLCLVWRYCRRLLFLWLPRLTLLRLPILLLAELAPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNY5</accession>
    <name>A0A8T0HNY5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG084500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12891" checksum="1E8302961CD2FF6E" modified="2022-10-12" version="1">MSESTNSSSVVLANSLKVTFENHCEFSDILEMACFYWLGFVVCRAHVAPVDLRRYLRSCEILRCNRQIWNDLNILVFLVYVYHARIHPVSPPHSLLLLMDTLKNPRRPSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS84</accession>
    <name>A0A8T0HS84_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG195200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS84"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15996" checksum="5BE69A467E694915" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSGARKSAESHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT00</accession>
    <name>A0A8T0HT00_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG215400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT00"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="10339" checksum="81BF37DECF968957" modified="2022-10-12" version="1">MIALRALGPQKTNSNGSEGPTSTTAPSLQGGTIRSSSSLPSGSTGMGDSFLPTSSGTRQASTRGSAPEDGEGLRSAPECHTAVRLSYAFLIWNNVLVLNGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTW7</accession>
    <name>A0A8T0HTW7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG246600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTW7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035762221" evidence="1">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9551" checksum="DDA4560E4ACA62F9" modified="2022-10-12" version="1">MLRMVGHWSRGLLMLLGGVPFWSFDDREVSLLAAWIRRGFWVTKEGRKQIRIHLLQDGDVLGVDWATSSIEHTFSVQLKDGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUE1</accession>
    <name>A0A8T0HUE1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG256500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="6495" checksum="4E53B9F1C20CD8B5" modified="2022-10-12" version="1">MGNSTSQDAGKPSVVSVLGAKRVIPTVRVFCCLTPILTSKEGGRSRVRAHGLVMTSGTNHDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUU7</accession>
    <name>A0A8T0HUU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG289000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF203">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0574764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6742" checksum="EE99D691C02FB488" modified="2022-10-12" version="1">MYLAGKLGVFDRQGHSWKLFLVVLPILGATFVGITRVDDYWHHWTDVCAGAAIGELTVAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYV7</accession>
    <name>A0A8T0HYV7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G072800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12662" checksum="9D3EAD1D3193E3CA" modified="2022-10-12" version="1">MIFHPHYNFELATINYGITFFTKCFKKYTRNSMARADLPTQVYLLTLNIIITANNQVSGLTSSQSQRRQPRQHTQCCPDFVLLRILACNILMKSYGNKASIQLLVDKCVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYY0</accession>
    <name>A0A8T0HYY0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G076400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYY0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5516" checksum="0D88553F7C9DDC4A" modified="2022-10-12" version="1">MFSYCFMFAGNLVIPDTDIDLQLVQNFCVASLERTDGPLMVFGPPSNTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0I3</accession>
    <name>A0A8T0I0I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G051000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0I3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="61"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="508"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="807" mass="92868" checksum="FA32C9EBDF8769E6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0K2</accession>
    <name>A0A8T0I0K2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mediator of RNA polymerase II transcription subunit 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G122900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mediator complex subunit 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0K2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005667">
        <property type="term" value="C:transcription regulator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021419">
        <property type="entry name" value="Mediator_Med25_VWA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12433">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12433:SF11">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11265">
        <property type="entry name" value="Med25_VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator of RNA polymerase II transcription subunit 25 von Willebrand factor type A" evidence="4">
        <location>
            <begin position="4"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="524"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="671"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="821"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="530"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="679"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="821"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="857" mass="88786" checksum="7BA30D4E332272E5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I173</accession>
    <name>A0A8T0I173_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G137900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I173"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15199" checksum="CA50A375F589E4E2" modified="2022-10-12" version="1">MYSSLNSISESKLFSLLRYSQAVNPDPPSHSRNSFPHTQHKPTRKQAEPKPKWNLKKNSPNQRIHNKDSPLGCSTTTQTLQLCTDLALNTLNTLELQTLSLDISDLESVPIQLIAGLFSQLLHSLQADRSTSRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5T7</accession>
    <name>A0A8T0I5T7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bifunctional lysine-specific demethylase and histidyl-hydroxylase</fullName>
            <ecNumber evidence="12">1.14.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G181500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="12">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ROX family. NO66 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.-" evidence="12"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5T7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051864">
        <property type="term" value="F:histone H3K36 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032453">
        <property type="term" value="F:histone H3K4 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.1500:FF:000001">
        <property type="entry name" value="ribosomal oxygenase 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1500">
        <property type="entry name" value="JmjC domain-containing ribosomal oxygenase (ROX), dimer domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039994">
        <property type="entry name" value="NO66-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049043">
        <property type="entry name" value="WHD_RIOX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096">
        <property type="entry name" value="MINA53 MYC INDUCED NUCLEAR ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13096:SF8">
        <property type="entry name" value="RIBOSOMAL OXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08007">
        <property type="entry name" value="JmjC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21233">
        <property type="entry name" value="WHD_RIOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6 12" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0678">Repressor</keyword>
    <keyword evidence="10 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="9 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="14">
        <location>
            <begin position="187"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0577783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="524" mass="58890" checksum="FA2E7D9475081951" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5X0</accession>
    <name>A0A8T0I5X0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G053800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5X0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12360" checksum="7B858D73D44F73EA" modified="2022-10-12" version="1">MRTAKYSLEGTPQQSLRSRKTSLTHQMEINLTLPIYPTTTITCRSPTPEFPNINSMYGATRAETTTSCILFFVNSYFGIGRSSFAEYKLNFPTVHWHLKFWRLSKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6Z6</accession>
    <name>A0A8T0I6Z6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G099800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6Z6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11231" checksum="4F132EB2EA6DC3B2" modified="2022-10-12" version="1">MSRIHSDENSATNMDHGSSDPPDSTRNGLLHFIVDDQITLVAPHRTEGDNHGGDDHTAFLITFEGGGLGIHPEAIVDDMLAVLPAPARHHILPDCCGEDFHFAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I727</accession>
    <name>A0A8T0I727_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G058000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I727"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="14062" checksum="F634ABF05325AE81" modified="2022-10-12" version="1">MHINTSPSDVLNLLDLLFKNIKLRNIIGCFNLHVGIFYIFTTLARWPDWCKPNARPSSVLTKVLYWLNLLISDPPVIYIFQSSGAHMIYPIRLDSRYLLLLPVCWSSSWSTSQATHGWKVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9I5</accession>
    <name>A0A8T0I9I5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G115900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9I5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035718564" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="46" mass="4843" checksum="F28DA8F8841A5DE0" modified="2022-10-12" version="1">MMNLLITGSIVPLILEAICNCRNPGLDQSCALGIFATIDTCQGNFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDE9</accession>
    <name>A0A8T0IDE9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">KC19_4G210400</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDE9"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000015">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000024">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000016">
        <property type="entry name" value="Somatic embryogenesis receptor-like kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47988">
        <property type="entry name" value="SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 22" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035718565" description="non-specific serine/threonine protein kinase" evidence="22">
        <location>
            <begin position="25"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="243"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="306"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="206"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="20">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="20">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0580916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="641" mass="71034" checksum="BCE964C6E19CBAB8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH48</accession>
    <name>A0A8T0IH48_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G045800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="240"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="312" mass="33892" checksum="3380E6CF4893AC76" modified="2022-10-12" version="1">MGQSKCDLSYAMPAANWDGAPRRPVAEVSGRALEGFPVTHLRPPPGAKPANLADLPFDNFEPPPELLKPSRNNLGGKILKLLKLRKKSSSAAPAVNLPMEDFHQPSLRVLHFQDLISHSTQFPSPVQVGFQVDDVTKRYNYDSDEHSGNYASDTQTSSSSMISSSSRNSNSSELESNRSSGTPRSPCLYSGQLTNSQLMANILISIMDEEDNASGSASDEHGSSEDDIPTMASLNGPHESAWHQPRDEMFNADSPTVRGRQSTSMKHLSSSGHHTPKAGTRTSVAVNGLTSPGPSRRFGKLDLSRIEVHKFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH54</accession>
    <name>A0A8T0IH54_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G043300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02028">
        <property type="entry name" value="UMPK_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.320.10">
        <property type="entry name" value="Hypothetical Protein Pfu-838710-001"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="CYTH-like phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="935"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="45"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="2">
        <location>
            <begin position="526"/>
            <end position="678"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="962" mass="106575" checksum="25DE4ED8839BE9BE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHC2</accession>
    <name>A0A8T0IHC2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NOT2/NOT3/NOT5 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G043500</name>
        <name evidence="7" type="ORF">KC19_3G043800</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CNOT2/3/5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030015">
        <property type="term" value="C:CCR4-NOT core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1020">
        <property type="entry name" value="CCR4-NOT complex subunit 2/3/5, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038635">
        <property type="entry name" value="CCR4-NOT_su2/3/5_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040168">
        <property type="entry name" value="Not2/3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007282">
        <property type="entry name" value="NOT2/3/5_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23326">
        <property type="entry name" value="CCR4 NOT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04153">
        <property type="entry name" value="NOT2_3_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NOT2/NOT3/NOT5 C-terminal" evidence="5">
        <location>
            <begin position="548"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="28"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="333"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="384"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="153"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="164"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="175"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="441"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0582217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="681" mass="70891" checksum="9EF57DFC9263F78F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHE2</accession>
    <name>A0A8T0IHE2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G052300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="13856" checksum="8886F6BB9470D449" modified="2022-10-12" version="1">MRRTHVTTSDAQLTSNSSPTQLTSDSPLPLPRNQNPAKPEHNHPSQQPGQLLLRSQLQSLVKRKASHDSSWSPDFNLQHPPLTPLVLYTGKHPPSLAPRLQKVIFTATLASSHHSSTHLNAPRME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II51</accession>
    <name>A0A8T0II51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-mannosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G070800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054593">
        <property type="entry name" value="Beta-mannosidase-like_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043534">
        <property type="entry name" value="EBDG/EBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Ig-like_GH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041351">
        <property type="entry name" value="Ig_GlcNase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041447">
        <property type="entry name" value="Mannosidase_ig"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43536:SF1">
        <property type="entry name" value="MANNOSYLGLYCOPROTEIN ENDO-BETA-MANNOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22666">
        <property type="entry name" value="Glyco_hydro_2_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18368">
        <property type="entry name" value="Ig_GlcNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17786">
        <property type="entry name" value="Mannosidase_ig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="beta-Galactosidase/glucuronidase domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-mannosidase-like galactose-binding" evidence="8">
        <location>
            <begin position="33"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 immunoglobulin-like beta-sandwich" evidence="4">
        <location>
            <begin position="207"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 2 catalytic" evidence="5">
        <location>
            <begin position="340"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="Mannosidase Ig/CBM-like" evidence="6">
        <location>
            <begin position="681"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="domain" description="Exo-beta-D-glucosaminidase Ig-fold" evidence="7">
        <location>
            <begin position="800"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF22666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="886" mass="99644" checksum="8FA2924F962C87C4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIM0</accession>
    <name>A0A8T0IIM0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G050900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIM0"/>
    <dbReference type="OrthoDB" id="2008962at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="226" mass="25343" checksum="B839AE9BDE7D2FE2" modified="2022-10-12" version="1">MASSDERNGFICCIIFAFFGFWTFFSIVGAIHYSVWYPHFELSDMRIRNFNVTPAAELNFDMDIVIEARHFSSIRRIEQYSYEIRTSHVGLDIGASSVPGFHPIHNKTMEIVSKQAATQLPMGSVLGELVRKDLNATGRVALRVYIEGQIYTSLFLAQKQRNGMICDLIVSPGKPLGSQIYEKKCCGELRCMSWCGSGESRSCCRQAQNCCLLPPSDLRSTISICG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJI4</accession>
    <name>A0A8T0IJI4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Peroxidase</fullName>
            <ecNumber evidence="12">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G171900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="9 12">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 12">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="9 12">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="12"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJI4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000023">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 12" id="KW-0349">Heme</keyword>
    <keyword evidence="12" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="4 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 12" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035966817" description="Peroxidase" evidence="12">
        <location>
            <begin position="32"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="13">
        <location>
            <begin position="37"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="47"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="80"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="129"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0583920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="327" mass="35287" checksum="EBF51086F4B9B509" modified="2022-10-12" version="1">MGFSRAMRGSLFAMLCMTAVILSLIFAPVAATRAHNGLENGFYRSSCPNVESIIFDSMRASYKADKTVAPGVLRLAYHDCFVRGCDASLLLDGSNVEKSSTINAGLHGFDAIDAAKEAVEKQCPNVVSCSDVLQFAVRDTVVLTGGKSWTVPAGRRDGKVSLESEVAANLMRPNNTVPVLLKAFQKKGLTASQMVTLAGAHTIGKAPCVQFDNRLYPNVDPSLPSKFASELKSKCPMAGITSTLVELDRDSSTKFDAQYFKNVVNKMGLLTSDQSMLEDSRTAGQVRENTDKSTFNDNFGKAMVALSKIGVLTGQSGEIRRQCRFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJQ9</accession>
    <name>A0A8T0IJQ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G112800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000018">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF4">
        <property type="entry name" value="INACTIVE GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="7">
        <location>
            <begin position="116"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0583141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="416" mass="47252" checksum="48FD2CDA537D7EA5" modified="2022-10-12" version="1">METFLQSVYYESGGYSTCDGMSKLDSRLQELEGFGEANRIFYLSVPHEIVPDVSKCLSRDAQSKSGWTRLIVEKPFGSDTDSSAKLADCLLDHLDESQIYRIDHHLGKELIENLTVLRFSNLVFEPLWTRTYIKSVQVILAEDWGMEGRGGYFDQHGIIRDIVQSHLMQTIALFAMEPPVSLDGEDIRNEKVKVLRSMRQPCLQDFCLGQYKASISKDGKSRIRGYLEEPGVNPNSLTPTFVAGVLYIDNARWDGVPILVKAGYGLIKHKVEIRIQFHNVPGNLYREQIGYNMDMASNELIIAVQPEEAIYLKINNKVPGLGTQLDSSELNLLYRQKYDEEVIPDSYERLILDVITGDNHLFIRSDELKATWELLTPLLQEIEEQKVAPEMYTYGGRGPVGAYYLGAKHGVRWADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJZ2</accession>
    <name>A0A8T0IJZ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoglycerate mutase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G119100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050275">
        <property type="entry name" value="PGM_Phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100">
        <property type="entry name" value="BROAD-SPECIFICITY PHOSPHATASE YOR283W-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48100:SF44">
        <property type="entry name" value="PHOSPHATASE C1620.13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00038362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24390" checksum="45B5B4A82BF6D7F1" modified="2022-10-12" version="1">MAVPSNVAELLVVRHGETDWNALGRLQGHAESDLNEAGKKQAQAVAEKLASLGLEFAAIYSSDLQRALDTAQAIAEKCQFRSKITVRENLRERCLGDLEGFTRTEARTAAPEALKVFMKNDDSLPIPGGGESMEQLCVRVQDAFEQIASENLGKRVVVVTHGGVLRTSHIIARGLPCIGKVVNASINTFRISDEKEWEICSWGDVGHLQDIGFLNTGFGGDKLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK40</accession>
    <name>A0A8T0IK40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mediator of RNA polymerase II transcription subunit 6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Mediator complex subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">MED6</name>
        <name evidence="8" type="ORF">KC19_3G095000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the Mediator complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the Mediator complex subunit 6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK40"/>
    <dbReference type="OrthoDB" id="344220at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.580">
        <property type="entry name" value="Mediator complex, subunit Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007018">
        <property type="entry name" value="Mediator_Med6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038566">
        <property type="entry name" value="Mediator_Med6_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13104">
        <property type="entry name" value="MED-6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04934">
        <property type="entry name" value="Med6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0010">Activator</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="195"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="197"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27546" checksum="B451491C43A2CF23" modified="2022-10-12" version="1">MAMVTPAEAVPGTEMTSISFRDQLWLSAYPLDRNLVFDYFALSPFYDRTCNNEQLRMESIHPLDMNHLSKKTGMEYILQDAQEPHLFVIRKQKREGPEKVSAQAAYYVLDGSIYQAPHLYNVIGSRVVRSLYHITNAFAQASTKLEKIGAGTETENGKPVSEVDADVQLKKSTAKVVDVKEVLRVDSILAGIMRKLPPAPPPPAPLVPVTNTVPGTEITQAPAASDVKQEQASTGGKPEQGSAKRLKVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL34</accession>
    <name>A0A8T0IL34_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G121600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="514"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="537"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="558" mass="59875" checksum="5121F7936DCFAA77" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILA2</accession>
    <name>A0A8T0ILA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA/rRNA methyltransferase SpoU type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G179200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILA2"/>
    <dbReference type="OrthoDB" id="5580682at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002130">
        <property type="term" value="P:wobble position ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1280.10:FF:000002">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="TrmL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971:SF1">
        <property type="entry name" value="TRNA (CYTIDINE(34)-2'-O)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="alpha/beta knot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA/rRNA methyltransferase SpoU type" evidence="6">
        <location>
            <begin position="87"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0584022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="29953" checksum="003223670ACF7849" modified="2022-10-12" version="1">MQEMAMLSQAHKCLASSFFHSSCTRLSYLRANAVGSWRRELGFATALPAGRPHSFRRGCGRLLVTASEGKKTSWGEVAQNDQQQRLLQVVLVSPQIPGNTGCIARTCAATCVGLHLVEPMGFKIEDSKLKRAGLDYWPYVVVKVHKSWNDFFTYFQEQEGEKRLLAFTKKGRNVHTDVKYKAGDWLLFGSEVDGLPAAALEQCSSGEYAGGTVRLPMNETYVRSLNLSVSAGIGVYEALRQLDSHTNYSTLDVTPTQPMETVLIGHNDGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMY6</accession>
    <name>A0A8T0IMY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA/RNA-binding protein Alba-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G203400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone-like Alba family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMY6"/>
    <dbReference type="OrthoDB" id="424402at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.110.20:FF:000003">
        <property type="entry name" value="DNA/RNA-binding protein Alba 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="entry name" value="Alba-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051958">
        <property type="entry name" value="Alba-like_NAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002775">
        <property type="entry name" value="DNA/RNA-bd_Alba-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516:SF4">
        <property type="entry name" value="FI09323P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13516">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01918">
        <property type="entry name" value="Alba"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82704">
        <property type="entry name" value="AlbA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA/RNA-binding protein Alba-like" evidence="5">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="139"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="150"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="183"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0584329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="265" mass="28881" checksum="7D4DCC17435520DE" modified="2022-10-12" version="1">MDRYQRVEKPRPETPISENEIRITTQGKMRNYITYATTLLQDKGASEIVLKAMGRAINKTVTIAEIIKRRIAGLHQNTSIGSTDITDLWEPLEEGLLPLETTRHVSMITITLSTKELEKTSTGYQPPLPADQVKPLAEFEYDGDGSPRGGRGRGRGRGRGRGRGGNEVANPEYNGLDGGWGRGRGRGRGRGRGRGGYRGRGREQDAGGYDEPSADVPPRGQGNEFPRDMSYSGRSRGRGGRSRGQGRGPGTGIVIRTEDTSGICI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN08</accession>
    <name>A0A8T0IN08_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Large ribosomal subunit protein eL40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G222400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IN08"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL40" evidence="2">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7131" checksum="B608B28F91054AAD" modified="2022-10-12" version="1">MLKIFTEPFILIKSWMICRRIYQHLHMTSAPCKSHRCGQTSGGAEKGRLKSSTLKPGAEDQEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPX2</accession>
    <name>A0A8T0IPX2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glycosyl transferase 64 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G239300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPX2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000058">
        <property type="entry name" value="Exostosin-like glycosyltransferase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053318">
        <property type="entry name" value="GT64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015338">
        <property type="entry name" value="GT64_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48410">
        <property type="entry name" value="GLYCOSYLINOSITOL PHOSPHORYLCERAMIDE MANNOSYL TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48410:SF1">
        <property type="entry name" value="GLYCOSYLINOSITOL PHOSPHORYLCERAMIDE MANNOSYL TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09258">
        <property type="entry name" value="Glyco_transf_64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 64" evidence="14">
        <location>
            <begin position="89"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0584851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="40529" checksum="5592BC4F68F05FBE" modified="2022-10-12" version="1">MESFSGGHDPCFQYSSSVKEKATMKSYRDRSYARWRTYGHSCFSGFYRIRLLIVFSFVFAATLLLTRASSLMGWSRDHQTPQVPFRSRYTVVINTWKRNDLLKRSISHYSACQGVDAIRIVWSEPNVPTERLRTSVENLVSVASRKKDEFISVQFDIHVNDDLNNRFKPLDDLRTDAILSIDDDVLVPCSTLETAFSVWTSAPHSMVGFVPRMHWVKAKNPSFGSYEYSYGGWWSVWWMGTYSMVLSKAAFIHKKYLDLYTNELPASIRQYVKDERNCEDIAMSFLVANETGAPPIWIKTRIYEIGSTGISSLQGHSEHRTDCINHFVTLFGSMPLVASNVKVADARHLWFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ44</accession>
    <name>A0A8T0IQ44_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G246800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6786" checksum="5A400FE38FCBC94F" modified="2022-10-12" version="1">MLRWLCKAQSFAKMRLLILVPDHLTISNGLLTKTHTQQVSINRLLRGKNISVDVETVHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQY2</accession>
    <name>A0A8T0IQY2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Saposin B-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G012700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQY2"/>
    <dbReference type="OrthoDB" id="69496at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007856">
        <property type="entry name" value="SapB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008138">
        <property type="entry name" value="SapB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051428">
        <property type="entry name" value="Sphingo_Act-Surfact_Prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11480:SF3">
        <property type="entry name" value="BCDNA.GH08312"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11480">
        <property type="entry name" value="SAPOSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05184">
        <property type="entry name" value="SapB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03489">
        <property type="entry name" value="SapB_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00741">
        <property type="entry name" value="SapB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035785372" description="Saposin B-type domain-containing protein" evidence="5">
        <location>
            <begin position="25"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="6">
        <location>
            <begin position="47"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="6">
        <location>
            <begin position="136"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="6">
        <location>
            <begin position="219"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="36827" checksum="001C6D24D95464C0" modified="2022-10-12" version="1">MAIRSVLWGVALVALVCIGSVAEGSHVNLGTVSRLAKFTRNEARVARINLCDTCLQLSQEAQMVLANPDTPKEVINVADQLVCSPLQPGLKKKCERMVDQYVPQAILELEALLGPDKLCFESGLCTAPALSAFEDERKSCMVCQDLATDALTYLENNKTRVEIVIALHLACAQLKELSKQCDLLVDMYTPRMMEQLENITPQEFCQMTKMCKPPKRVLASNDCATCQFVILELKIKLQDPQTQEKVLDVLMNGCNRVVNHVDECKALVVQYGPFVLANLDKILDSQAVCCKAGFCKSSICPQKAKLWTEMMTELLQKDSSLIELPQEGLVSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRC8</accession>
    <name>A0A8T0IRC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G245500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9105" checksum="0B5E728080D1E84D" modified="2022-10-12" version="1">MVVGDGGGGDGESRGGSCGIFGGGPRTAGWLAVSERCGRAYVVPAVPGRLKLAISGKRRFTRLLRFPAVGFASPRLNYQSILRLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRH1</accession>
    <name>A0A8T0IRH1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G082600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12781" checksum="0003F61AC86A8BD8" modified="2022-10-12" version="1">MDRRVVRQHDNYFVTHDSSISAPTTVPFCHPRQFHFRSTPRQCQDQHHDSSNIVPSNRVFCVPTFLIADHCVRYSTCVTVEEGAGLIHRGSVFWCAIVVGYVVLIHASAGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRH5</accession>
    <name>A0A8T0IRH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Inactive purple acid phosphatase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G249300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ESV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043036">
        <property type="term" value="C:starch grain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005982">
        <property type="term" value="P:starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052495">
        <property type="entry name" value="Alpha-glucan_binding_chloro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34113">
        <property type="entry name" value="INACTIVE PURPLE ACID PHOSPHATASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34113:SF3">
        <property type="entry name" value="PROTEIN EARLY STARVATION 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="449"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0584993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57318" checksum="843D9B67386896B0" modified="2022-10-12" version="1">MAVKLSGSVTALFQSLRSGANGRREGSEQHEGSQSKGRGVWARLNCARKLCVAVSIAGDRQHFFGRIAGLAVGTLPKCNELSRKPRVSCALSSFELDDVDLRRETGDGWSSSTTKQAPKAVHHRTTCNFQKSNGTSLRVPTPAQTFASARPRKPGEQDESLSRQTQRRCMPQPRDTPPKRDTGIASEKDWGINLNKEIKSESGVNEDGSSWYSDSGEDLGENGYRCRWTVMGGRSADGSSEWKEAWWEKSDWTGYKELGAEKSGKNAQGDTWWETWQEVLKVDELSNLARIEKSAQKQAKSGTGSAGWFEKWWEKYNAKGWTEKGAHKYGRLNDQGWWEKWEEQYDGRGAVLKWTDKWAESDTGTKWGDKWEEKFDHGVGTRQGETWHNDDKGWSRTWGEEHFGNGKVHKYGKSTSGENWDNIVEEGTYYQAEPHYGWADAIGNSVQLLSIEPRERPPGTFPSVEPTPRDQQQNQEPVMKDDSREEEEQQPKQEPGSDMDEGQPRQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITR2</accession>
    <name>A0A8T0ITR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G097700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12416" checksum="99E24C5FA5F66DF5" modified="2022-10-12" version="1">MGLQKQGFVGFRQALNFTSSGWVPELFADHKLFRFFTFILLMVYLAPRWPLGKRYSLHIQRRRSRNHEGMAVDAWSLNRLLLGGLLGIDQAIVCLSLQHKGCKLQGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITT5</accession>
    <name>A0A8T0ITT5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G038700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="26125" checksum="C5D6EF24042FE23B" modified="2022-10-12" version="1">MANQQQPPDPPHDYGQPADRRREIEKDPILRLFLQDWDDEKKQMLLSVESYRGRCNAAKAELYQLMGFYSVFQGVVFTAVSTASKLTCETSFFPAVLSGLASIATIVSVHYKLDYYTIEKVKFLKAQHQSGNIIKKVRKLRGNGASFNFASLGDPEVQKAELQEKVNDEKKRRRWIWWIVMLFLALFTLVILSSCIIVPCWDLDQHKLKGCTFHGLCWWDKGNATTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW24</accession>
    <name>A0A8T0IW24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G143400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="247" mass="28332" checksum="6A5BD3B28BC9AB9F" modified="2022-10-12" version="1">MELDDIQQELYKSTYKDNLQRYDVKNVAINKFLEAMSKQQRNLTDSETPIESSIINETTPMNINATMDETTSMNINATMDETTSMNINVIPTEDIGKQIITNTLITIHDHCQSREQGISNLLHDDDQVNGWNFRRGLQERLLLKEVTNVEKRNAEIATEVNGTNNESNLQLTRPVIWGTCKYRDLWVRASTIEEDVHMDNASPILLEEEEEICSPKDYDKTEVSFPTTPQSYSHRTIPTDKVMDEGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW85</accession>
    <name>A0A8T0IW85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G140400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47262">
        <property type="entry name" value="OS02G0132600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47262:SF1">
        <property type="entry name" value="OS02G0132600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="397"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="469"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="504"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="539"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="574"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="699"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="768"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0587096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="890" mass="99547" checksum="76CA5A3D6BDA8B3C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWM4</accession>
    <name>A0A8T0IWM4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G178200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="282" mass="34916" checksum="28C8E9BEA393F7A2" modified="2022-10-12" version="1" fragment="single">LPLLYLSFLSFNSLSFSFLFHFILSFILFFLSFYFLVPFIFSFILFSLSFFFLFHFIFSFILFSLSFSCLLHYNLSFILFSFSFYFLFHFILSFILFSLSFYCLIHFFFSFVLFSLSFYSLFHFLVSFIIISLSFYFPFHFIFSFILFCLSFYSLFHFIVSFILFSHSFYFLIHFIFLFILFSLSFYFVFHFILSFILLSHSFYFLSHFIFSFILFSQSFYFLIHFIFSFILFCLSFYFLFHFIFSFILFCLSFYFLFHFLSRLHIIFNLNIYFCFFSFLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY97</accession>
    <name>A0A8T0IY97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G195900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032707">
        <property type="entry name" value="MYCBPAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48421">
        <property type="entry name" value="MYCBP-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48421:SF1">
        <property type="entry name" value="MYCBP-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="340" mass="40039" checksum="53A20F51915AB8D2" modified="2022-10-12" version="1">MYRRTLYTKLPPQCNMLELVPPRRSKMFLKWQDLRKKDPPPGLKPKPKERLHIWQKVERDKEENVLEDYYWFYEEWDRINKMFIRRFYKTFPELLMERIHHYRIKVENAILLAGCILTLAEDDDSNDPSKWEESLRKYPWFPSPGVPLKPPWDDGSNDKPKPVARPEDIAPDRVGRADRDNPKFEYFKDRWAHLKKGEDDWGAWEKFCFKMAAAIARAEPHYPDFVNPPEFGGLLILGKRLKRPVPEPPPPKCPPIPIIPPVKKAIQYVPGPAAMISLTYHFFVNQVGEQSIKSVLLENVGETVLFYTWERRPMEALITTPKAHLGLCSLPFCRPIWIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2P2</accession>
    <name>A0A8T0J2P2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G282000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2P2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="232" mass="24833" checksum="CA47C5DF8934AB57" modified="2022-10-12" version="1">MSMGNCHQDVAVPEIVCHGCCGDSPRFCVANPAPLGLCGFALTTFVHSCYNAGIFGTSGTTSPPNVVTGLSVFSGGLVGLLAGMWEFETGNTFAATTFSSYGAYRLSYAATLIPWFGVYEAYEGHEEDLLAANAVLLLGWTVFTFMMWVVTLTIRANVALRTVFAFLTITFALLTISEFMAGSPAAQLLKRAGGFFGVFTAIIAWYMALAGILTPENSYFILPVGNLRDHQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J315</accession>
    <name>A0A8T0J315_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G088800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J315"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035862848" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="5908" checksum="4402A92B4D4A1D1E" modified="2022-10-12" version="1">MRHDSGWGRKSVPWFLGSFVLLFVGPGTHQNLSCVGSAGVCRGRRPTVLLGVVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5P4</accession>
    <name>A0A8T0J5P4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G104000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5P4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="400" mass="45689" checksum="092EC8A7E863362C" modified="2022-10-12" version="1">MDLSTALWSDLPSEMVDQVLSYLPLPDLCRYRTVCKRWDRLMCDPKFGSLCAQNASKREASLIAMRYMTCNTFFTGWCFLDVNARRWYVFKEDGKQIRSSFPHGDVRMDGGLVCQYWGPDGIIVYNPVSQTYRKLPCTPKHFSEKTYFSELTLVVDNISQSFKIFLFTIPENKSRILNIVPLKLVYDSVTNEWKTSTSPVCIGSGSKLNGSGVIFQGYLYTIRRRIYFEKSIRDFRDEYTVGRYNLVKDAWEDLDVPIIIEISSACLVVSANRLFLVAWSKGHGSGFPYGRPSWSFQLSELKIPDMTREVLFEMSEADVVEGFETIEDGTTNYSLPGMSAFSFGNSILFMSTSTGISAAFDVVTRSWDRNFPPNPLEYLPNLNCSWAGEQMNLLLPCTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7P2</accession>
    <name>A0A8T0J7P2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G182800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7P2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="408" mass="44664" checksum="941552F8539E0C59" modified="2022-10-12" version="1">MKFFGWGRKKDPPPIEPAYQEFKDSDAATSINSPGSAVCGSVQLVGQDDQPKISTYQRVAIPPQSQDFFGEAVVDMDSETWEVRLQETIRFVFRHEQEGLLAIGTFALDQLAGMTHIDGRRKSPAATEHRVNPRRNSFSSVEVVIREVRSSDDDNESHHSMRSPIPGCKRKESYPVFGDHDASSGVHCRGLSVGGTKSVTDKNQYPPCISYASANMTTQEAVSKPRGETRGHADSSTTLDHDHSDSEGFYSPGICGLFRSRSRRTQKDSGKEKRKKPPEKQKTISYSCEQLNEADSTKGSLGAQLGRLWRSACTGSSDSAKVSPEKKPIPCPPQESTPEPVQAQGPPCIANVEEVDGAGAPAVPKPSQSSEVGEQRKRRGHSFGKGWASCAHNGNWIRTDSEFVVLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J880</accession>
    <name>A0A8T0J880_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G177400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid/choline transporter (ACT) (TC 2.A.3.4) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J880"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015185">
        <property type="term" value="F:gamma-aminobutyric acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015180">
        <property type="term" value="F:L-alanine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000026">
        <property type="entry name" value="Amino-acid permease BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF30">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="478"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="521"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="597" mass="65097" checksum="6A3F8315548DED0B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9C8</accession>
    <name>A0A8T0J9C8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G243000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9C8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04873">
        <property type="entry name" value="ACT_UUR-ACR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009902">
        <property type="entry name" value="DUF1442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33593:SF30">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33593">
        <property type="entry name" value="DUF1442 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07279">
        <property type="entry name" value="DUF1442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="445"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="524" mass="58199" checksum="66570A1BAEC8F395" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA68</accession>
    <name>A0A8T0JA68_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G249700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00657">
        <property type="entry name" value="Ferritin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007402">
        <property type="entry name" value="DUF455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782:SF4">
        <property type="entry name" value="DUF455 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42782">
        <property type="entry name" value="SI:CH73-314G15.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04305">
        <property type="entry name" value="DUF455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="125"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="482" mass="53103" checksum="B47CBDEF49BCA796" modified="2022-10-12" version="1">MASALSMASLSVEVQLAKAAIRGRILRDSEARGESTGTIGYGHQLSRMHAFRTPSLRSSSSQTRPCVSARALTPAQEWVGLPHWRTKPMNELRVWGKRDVPTSARNEWEDIAAVATTDLNAHYKLQLHQEKLHSLEERIVKLKLEREIASLAEWGAIVLNTADPVEKAVLTHQAYRLWCRGDLPLGVAYAPDSPARPAKPELVHPRKIPPVGTILPPSAHALHNLAHIELNAIDLAWDTIVRFSSASGELNPQFFTDFAHVADDESRHCLWCLQRVAELGYSYGDMPAHNLLMIDCQKSSGSVMERLAIIPMIQEARGLDAGPRLFERLVGNGDTRSASMTKRIAEEEVGHVAVGVAWFVDVCKRLGVDPADRFQGLMIEGDLELRGPFNHPARLLAGLPRDWYDSSYDPASPDAEDSSDSHDESAYSTVVRRSSVQAVTDLKVGPSNDGHENGVLKTSSRLSEVYDRLATVVAMEQDNADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC18</accession>
    <name>A0A8T0JC18_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G331000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16700" checksum="40A0F44B5A5C72B5" modified="2022-10-12" version="1">MQGRSLLLPFPGKCSVDYKKPAPPLVAVDSRCCCLPLANLTQLQCPRNPAHSAEEPLHEATEEPTSKPNINLCMLCSAALRHRLTAISSATVSDQPLHSRYQATLYCTTRHAIVQLPYIARVAFIIDEAISFQLRRHECRVVPLLKRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCP3</accession>
    <name>A0A8T0JCP3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-ketoacyl-CoA synthase</fullName>
            <ecNumber evidence="10">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G255600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:32727"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:90725"/>
            <dbReference type="ChEBI" id="CHEBI:90736"/>
            <dbReference type="EC" id="2.3.1.199"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCP3"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009922">
        <property type="term" value="F:fatty acid elongase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000028">
        <property type="entry name" value="3-ketoacyl-CoA synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012392">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013601">
        <property type="entry name" value="FAE1_typ3_polyketide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31561">
        <property type="entry name" value="3-KETOACYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08392">
        <property type="entry name" value="FAE1_CUT1_RppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036417">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FAE" evidence="12">
        <location>
            <begin position="110"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-terminal" evidence="13">
        <location>
            <begin position="417"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR036417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0592481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="540" mass="60346" checksum="4A6A3CE8AC1EA0C2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD43</accession>
    <name>A0A8T0JD43_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Pectinesterase</fullName>
            <ecNumber evidence="5 12">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_1G277900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="5 12"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD43"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000008">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF136">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036511327" description="Pectinesterase" evidence="12">
        <location>
            <begin position="28"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="14">
        <location>
            <begin position="93"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="48"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0592748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="45139" checksum="07207324871A68AE" modified="2022-10-12" version="1">MGLLCRKPLLLILLAVVCCTAFIAVAGEEDDSMTNWLKFMAETSGSDADPEYDSPYDNSYVAQPDSHPDGPKSGASAGMFVKFPKPQGKSKKITVSKSGKDDFTTINAALDSIAEHTKHRTIIHIREGVYEEKIFINASKPYISFLGDGQEKTIIQWGDKAGDFDDDDQLLKTYKSATVGVNSQYFIAENIQFRNTAPQPPPGSVLKQAVALRITGDRAAFYNCSFYGFQDTLYDHKGRHYFENCYIHGSIDFVFGNGRSLYKNCHLHSVAKTFGSVTAQKRNESHMNTGFSFVDASLTGSGPIYLGRAWGNYSRTVYSYTWMDNIVYPPGWSDFGYSDRQTKVFYAQYNCKGPGAITNERVAWVRELTAEEAKPFLTVHFINGKTWLKKYIGKKIKTKKPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4K1</accession>
    <name>A0A8T0G4K1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">protein-S-isoprenylcysteine alpha-carbonyl methylesterase</fullName>
            <ecNumber evidence="10">3.1.1.n2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G073600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + H2O = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + methanol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48520"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="3.1.1.n2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the AB hydrolase superfamily. Isoprenylcysteine methylesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.n2" evidence="10"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4K1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000084">
        <property type="entry name" value="Isoprenylcysteine alpha-carbonyl methylesterase ICME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049492">
        <property type="entry name" value="BD-FAE-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050300">
        <property type="entry name" value="GDXG_lipolytic_enzyme"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081">
        <property type="entry name" value="AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48081:SF33">
        <property type="entry name" value="KYNURENINE FORMAMIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20434">
        <property type="entry name" value="BD-FAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="BD-FAE-like" evidence="13">
        <location>
            <begin position="324"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00038928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0554216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="610" mass="68209" checksum="7C0E4A98AE00444D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8I2</accession>
    <name>A0A8T0G8I2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Partial AB-hydrolase lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G163800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8I2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000091">
        <property type="entry name" value="Gastric triacylglycerol lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="2">
        <location>
            <begin position="293"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="753"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="887" mass="99220" checksum="42EA785F26512B3C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8V4</accession>
    <name>A0A8T0G8V4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDP-D-glucose phosphorylase 1</fullName>
            <ecNumber evidence="5">2.7.7.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_12G091900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GDP-alpha-D-glucose + phosphate = alpha-D-glucose 1-phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:30387"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:62230"/>
            <dbReference type="EC" id="2.7.7.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GDPGP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.78" evidence="5"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8V4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080048">
        <property type="term" value="F:GDP-D-glucose phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026506">
        <property type="entry name" value="GDPGP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058865">
        <property type="entry name" value="GDPGP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058866">
        <property type="entry name" value="GDPGP1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20884:SF8">
        <property type="entry name" value="GDP-D-GLUCOSE PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26216">
        <property type="entry name" value="GDPGP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26217">
        <property type="entry name" value="GDPGP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GDPGP1-like N-terminal" evidence="15">
        <location>
            <begin position="86"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="GDPGP1-like C-terminal" evidence="14">
        <location>
            <begin position="263"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="52"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="446"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF26216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF26217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0554439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="472" mass="52787" checksum="01051CF4B5D8358F" modified="2022-10-12" version="1">MLTIKRVETVVSINQQLDQAPGCGRDCLGNCCIPGAKLPLYTFGVKRTSGFNKRAHSGSDDHCVPEDTGDSDDYGNSDSQQDNYFLDELLLAQWEDRMVRGLFRYDVTACETKMLPGEHGFIAQLNEGRHLQKRPTEFRVDQVLQTFDPKKFNFTKVGQEEVLFQFGPSEDDISEYYEKAPVLASPNVVAINVSPIEYGHVLLVPRVLDRLPQRIDQDSFLLALHFAAEANNPYFRLGYNSLGAFATINHLHFQAYYLAAPFPIERAPTTRVAYGRKKGGVKVYELTKFPVRGLVFEICNSMEDLSEAVSNACIYLQNENIPYNVLITDRGSRVFLLPQCFAERQARGEVDQEILDTQVNPAVWEISGHIVLKRRTDFELATEEYAWKLLAEVSLSHERFEEVKAACLKAAFEQNSEVVLADTDGFSTVLSNGGTYNCVERANPTLKGSQKTNSSMDAVVPGNHGEGLSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA83</accession>
    <name>A0A8T0GA83_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G127900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA83"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47770">
        <property type="entry name" value="PLANT UBX DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47770:SF1">
        <property type="entry name" value="PLANT UBX DOMAIN-CONTAINING PROTEIN 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035913839" description="UBX domain-containing protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="3">
        <location>
            <begin position="306"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="183"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0554889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="56505" checksum="FD708EF95AA321CE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAQ8</accession>
    <name>A0A8T0GAQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G039200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035790707" description="NADH dehydrogenase subunit 4" evidence="2">
        <location>
            <begin position="24"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8877" checksum="C8795782633096E4" modified="2022-10-12" version="1">MAFCHGSLSSLLCLLVPWLSVFALLSFAPPCHNTRLQYSTIFLLLVHTWFFLSLFTWFGWSFFLAPWFLCLGNLVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC21</accession>
    <name>A0A8T0GC21_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_12G176900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:68748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:68752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58392"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC21"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004615">
        <property type="term" value="F:phosphomannomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03089">
        <property type="entry name" value="PMM_PGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000014">
        <property type="entry name" value="Phosphomannomutase/phosphoglucomutase isoform B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000010">
        <property type="entry name" value="phosphomannomutase/phosphoglucomutase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.120.10:FF:000022">
        <property type="entry name" value="phosphomannomutase/phosphoglucomutase isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.120.10">
        <property type="entry name" value="Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.50">
        <property type="entry name" value="Alpha-D-phosphohexomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050060">
        <property type="entry name" value="Phosphoglucosamine_mutase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42946:SF1">
        <property type="entry name" value="PHOSPHOGLUCOMUTASE (ALPHA-D-GLUCOSE-1,6-BISPHOSPHATE-DEPENDENT)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42946">
        <property type="entry name" value="PHOSPHOHEXOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="Phosphoglucomutase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="Phosphoglucomutase, first 3 domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="12">
        <location>
            <begin position="96"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="13">
        <location>
            <begin position="290"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-D-phosphohexomutase alpha/beta/alpha" evidence="14">
        <location>
            <begin position="380"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0555549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="615" mass="65933" checksum="9257B4D2182E3973" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCH6</accession>
    <name>A0A8T0GCH6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G176400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="16326" checksum="330C864BADF59D71" modified="2022-10-12" version="1">MHSHLLLLLLLFLLLLLLLLRLLPSHIAFHKSVAHVLSNHATLLPTPPMRHLRKFIPKLALKLGHSSKPEKPTSSNQSLSIPQLQTSHHIHFLAKWSLHQLPLSLSLCKLPSIHESSQHHVSYHFIQTNSTSSKNKKKSTQILT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD89</accession>
    <name>A0A8T0GD89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_11G057300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="4"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000002">
        <property type="entry name" value="Prolyl 4-hydroxylase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF123">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE 10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="16">
        <location>
            <begin position="156"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0556487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="285" mass="31726" checksum="D4F1B76040973832" modified="2022-10-12" version="1">MARLSRGQRTGAGTVALMVLALLSLVLMTMLVLGLVAVPSVSRSATEDGAVVELKLPSHRHGDEIPNPLTPWVEVLSWEPRAFLYHHFLTQEECNHLIDLARPNLVKSSVVDSETGKSKDSRVRTSSGTFLMRGQDDVIKRIEKRIADFTFIPVEQGEGLQVLQYKESEKYDAHYDYFHDAYNTKNGGQRIATVLMYLSNVEQGGETVFPASKVNKSEVPDWDNLSECAQRGKSVRPRMGDALLFWSMKPDASLDPTSLHGGCPVINGTKWSATKWLHVGNYLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE97</accession>
    <name>A0A8T0GE97_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G070100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035771464" description="Secreted protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="8639" checksum="DCFB7A8AFA811571" modified="2022-10-12" version="1">MAPDRCDAGRARRNRCAKFCAMVCVLAASVSAAWIGSCETGVCSASVLLECQRGRRRQPPRHSPPLTGCCRSTVGGLAGVCAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEB9</accession>
    <name>A0A8T0GEB9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G097600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEB9"/>
    <dbReference type="OrthoDB" id="276721at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044877">
        <property type="term" value="F:protein-containing complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000349">
        <property type="entry name" value="Uncharacterized protein At1g32220, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051207">
        <property type="entry name" value="ComplexI_NDUFA9_subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126:SF16">
        <property type="entry name" value="MIOREX COMPLEX COMPONENT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12126">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="2">
        <location>
            <begin position="58"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="279" mass="29660" checksum="D8A53F90E1ED0C79" modified="2022-10-12" version="1">MAGRGGKQALQHLHHLRDGAVGASRAHYSVSTASRGSTAEAEVMEPKSGERKKVLVLGGNGYVGTHICKEALSKGVPVVSLSRSGRPKVAEPWSNDVEWVKGDLFQPSNWRNTLDDVSAVISCVGGFGSNEQMQKINGVANVQAIRAAAEAGVKRFVYISAHDFGLPSFVLRGYYAGKRAAEDELLSKFPYSGVILRPGFIHGVRQVGRVKLPLNAIGSPLELVLKNVKPLSQLPLVGNLLVPPVKVVAVAKAAVRSATDNAVPPGIMDVWGIMRLSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEZ3</accession>
    <name>A0A8T0GEZ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_11G050900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family. BCS1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19510">
        <property type="entry name" value="RecA-like_BCS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025753">
        <property type="entry name" value="AAA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058017">
        <property type="entry name" value="At3g28540-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14363">
        <property type="entry name" value="AAA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25568">
        <property type="entry name" value="AAA_lid_At3g28540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035794418" description="AAA+ ATPase domain-containing protein" evidence="7">
        <location>
            <begin position="19"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="221"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="428"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="492"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="514"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0556398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="525" mass="59658" checksum="1A83B7590D45C3FB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFE5</accession>
    <name>A0A8T0GFE5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G007800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFE5"/>
    <dbReference type="OrthoDB" id="1919527at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="261" mass="28955" checksum="5AC663E71EA66758" modified="2022-10-12" version="1">MVLTDHIAQQGGSTFIQAKDGSLLGFQGQQPSTALVSTWNLFRLALVSACMLFAILVSTIYSLHRAGGAPSTRGGWLETKQSPLHHILLRDQTLSDELKNTDCGLLQRINEKATLELETLVIAETVVPYKDRVMLSKYVKHQLDASNVISNQQKSAVMTMVDMAPVEGSVNKEDRGEGGSLRNSAVIAMFKIHQNNIHFMLIGVRVEPRLGIWRRISAKERNDWNDVLSRVLYNKVRGEAKTFLAYGTPTRLLNPISATPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFE7</accession>
    <name>A0A8T0GFE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_11G125500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="29"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0557385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="474" mass="53792" checksum="E57886CA1567E5A9" modified="2022-10-12" version="1">MRFSTLEVSDGHANGGGDPDETDQRVKRKSNMYFAAAYNITAIIGVGVLGLPQAMVFLEWGGGLVVLFGTFFFTYFTMTHLVKLHEFEIVNMNKRHDTYHSLGIRALGRKWSRLVIVPLQMVVEVSLDILFTVAAGEAMNRIHDINHCHEPIHIFVWFVTFAAIQIVLSVVVQNFQSIRWIVVMAAIMSICYTTIAWTTILAVGNNEKVHYRLPMYLTVDNDAPAQELSDPDLALRVFNSIGVIAFAYAAHNVVLEIQNAIPSTPEKTSETEMMRAVWITYVVVALCYFPVAIVVYTKHGNKISQNVLSFLQYHVKAPSGVVVTANVMLILHLIGSYQVFAQPVFKLLEDRRQLGRHDYFKKFVIRFIYIGFSTVIAMIFPHFSPLLGFFGGFAIAPTTYILPCIIWLKINNPQRRWRSLDWYLNSAFIILGFLLMLVASVGGLSILIKESKDSRLLWTPHWRQSVFYNCPPQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFW1</accession>
    <name>A0A8T0GFW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ubiquitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G010300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="91"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="174"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="269"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="491"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="593" mass="67541" checksum="5CC144592A95B7E4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG47</accession>
    <name>A0A8T0GG47_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-tyrosine-phosphatase IBR5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G015000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033549">
        <property type="term" value="F:MAP kinase phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009738">
        <property type="term" value="P:abscisic acid-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009734">
        <property type="term" value="P:auxin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18534">
        <property type="entry name" value="DSP_plant_IBR5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000079">
        <property type="entry name" value="Protein-tyrosine-phosphatase IBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044212">
        <property type="entry name" value="IBR5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47244">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE IBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47244:SF1">
        <property type="entry name" value="PROTEIN-TYROSINE-PHOSPHATASE IBR5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="3">
        <location>
            <begin position="45"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="4">
        <location>
            <begin position="102"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="263" mass="28938" checksum="D03D44404E8F1E45" modified="2022-10-12" version="1">MRKRERENPCFVCGHYHKFEDGEVCGICGHRLQEAAEKGPQQSAFSSEILPQFLYLGSYDNASRAELLKAQNISRILNTVPTCQNLYKNSFTYHSLKEDKSLPFTECLEFIEQARADKARVLVHCMSGQSRSPAVVIAYLMKYKQWRLPQAYQWVKDRRPSINLTEAVAQQLQHFESEIFGNSVPSTPIINTAAGGVTFGFGYSAPAAEAAVPTFMPHPMAHSAGQGALFGSGGVAMIPAPGFVFGAAKHDPRAAMDQSMDSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGP8</accession>
    <name>A0A8T0GGP8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G121600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGP8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42697">
        <property type="entry name" value="ENDONUCLEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42697:SF1">
        <property type="entry name" value="ENDONUCLEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="91" mass="9664" checksum="0D3A4C93A5893F17" modified="2022-10-12" version="1">MGSAGGRLELHWFFVDCFTVPASYDGNGRNFTATSPTGRFADGAAAIDGLFVSHIEVQGKNIFYVSCSEEFCLGLSSLLMISFASGWGLGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGR1</accession>
    <name>A0A8T0GGR1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Factor of DNA methylation 1-5/IDN2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G041700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080188">
        <property type="term" value="P:gene silencing by siRNA-directed DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045177">
        <property type="entry name" value="FDM1-5/IDN2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005379">
        <property type="entry name" value="FDM1-5/IDN2_XH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21596:SF3">
        <property type="entry name" value="FACTOR OF DNA METHYLATION 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21596">
        <property type="entry name" value="RIBONUCLEASE P SUBUNIT P38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03469">
        <property type="entry name" value="XH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Factor of DNA methylation 1-5/IDN2" evidence="2">
        <location>
            <begin position="247"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="404" mass="45749" checksum="24A3B6D42E246F58" modified="2022-10-12" version="1">MRPGPVNRQRVVQVKYLHQHHAIEITYDDVYQAIGCLAQVENPKAHLWHEKVRYLRFYVLPCSKSMKYEYFASIFDAKPEDPCPLLANSKTYSHFSHRICEDCFKGLVSSGRLDCYCVGLDGQPESNHTKKQKGKQLKQIVGGKREKAGAKEVEVEVATAKVGRKVVEPATVDLSQEDFNENGYIKRICELEDQLRDSEEDVDAGRDLVSQLTVSHRQAKDEIEDARAKLLASRMLHRYGTAEIGIKVLGQINTDGWWEECKDRFLGNQEKFGAWQSRVDQLLRNQTFNPIKVVPDGKGGFQNVVDDDDEELTTLRKTYGPLVANAVGVAALELADWNPSGRYNVSMPWDFNANQKASMSQVFQLFADVLQEKEKEIKEKDKQLKALAPAKTSGSASKRRRGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GL34</accession>
    <name>A0A8T0GL34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_10G165100</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GL34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000385">
        <property type="entry name" value="Leucine-rich repeat family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000417">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000260">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase RPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051716">
        <property type="entry name" value="Plant_RL_S/T_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053">
        <property type="entry name" value="LEUCINE RICH REPEAT FAMILY PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48053:SF113">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="13 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15 20" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 20" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 20" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="20">
        <location>
            <begin position="730"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="800"/>
            <end position="1087"/>
        </location>
    </feature>
    <feature type="binding site" evidence="19">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0560241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1102" mass="119515" checksum="4D5B6834F99182AF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLQ8</accession>
    <name>A0A8T0GLQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">KNOX1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G045100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005540">
        <property type="entry name" value="KNOX1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03790">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01255">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KNOX1" evidence="4">
        <location>
            <begin position="384"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="56393" checksum="42817A5995496E1D" modified="2022-10-12" version="1">MVVIRQGSDRLGVYSPGSPGSQSEEESQARCRRSSSRAGCASEGDFIERLWETEGVCAAERAFNEKERKRKREAGESAAHGLDQFHLRHDGHFAAGPARLKLKGHDLKKEALHQGEQQEAEPQRAWCGDSVAKETSIAVTDADVDGDGGGDLQEEYCGLQCFESKEGATVARSHAPGQGSPPQQTECFNSSFDLLKIEPRKLRTEYTSGGSCKDVQPVAGRIPSPCLSVESMHSSCGPVSPPCAQKPLAYDHVGRIVYDNDSCPVGSSYDCTPADFSPPDTPWGCHVKKPEEPISNHVPSCVTYADADRLSPRQYGLYEMANVGQLRDSSERVTRRFRNMGIGNGFSDSSCVRSGARAVTEALIDAHQETLQKARNPGTATRLDKMKASILCHGFYPRLIEAYMSRRMVGASPTLKMRLRAIQAQVQDWRPSDNDNEAVNKFHSMITTYEKDLERPFQKSMSFCDGLERELESMELTTTRAASVANRSIPQEHTRSIYDTYSSRGYPYGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLR4</accession>
    <name>A0A8T0GLR4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G140300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035936218" evidence="1">
        <location>
            <begin position="24"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="6155" checksum="B054B6AC3F610E81" modified="2022-10-12" version="1">MSSIFMLCTGIVCLLCNLHDSLLKEIRVVKTPCSCEIRDKSFFEETNLRLCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPD4</accession>
    <name>A0A8T0GPD4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G152700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPD4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="17019" checksum="5C6F834353AC0736" modified="2022-10-12" version="1">MVRRFLGAGRNWKKPCCSWRWHLENGRGGCNGVMVRSYDIIIGILGGVHFWNMFIRSFPSLYFSGRKAILGIRVLGGKFSLLFEFFNWVFCLVYFFFFCKGRVLDFRHSATGGAICVSIYCRNVYLACVNFGWYGAFSKKCGWESHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPR7</accession>
    <name>A0A8T0GPR7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G030300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="13032" checksum="F866311FCB2BBC21" modified="2022-10-12" version="1">MVNDYKLKQQPITRKLHPCFPVSDPYLACKTIQYDPQPDLYYDGELRCKAPKSTDKYVRIRELHTSMDSTGLIRIRTTQLRSSEWIAPYICITLSLCDKRTELGAIPPELRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQS2</accession>
    <name>A0A8T0GQS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G107500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15896" checksum="687D1255F8295D1B" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKAARLRSTTTGSGARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRG4</accession>
    <name>A0A8T0GRG4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G129900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRG4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035853299" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5960" checksum="AF838D9F8A417E2C" modified="2022-10-12" version="1">MLFLQIGLLFFSVGDIVARFQGVSQILRLLQELRSRKFFLLSFRPYSSASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRS1</accession>
    <name>A0A8T0GRS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G031200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="479"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="238"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="9">
        <location>
            <begin position="339"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="647" mass="73156" checksum="83B987B5E18F9405" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS28</accession>
    <name>A0A8T0GS28_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">pectinesterase</fullName>
            <ecNumber evidence="5">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_9G149500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="5"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000008">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF112">
        <property type="entry name" value="PECTINESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035845640" description="pectinesterase" evidence="10">
        <location>
            <begin position="23"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="11">
        <location>
            <begin position="73"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0562476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="366" mass="40668" checksum="EF04B8A3E75FE74C" modified="2022-10-12" version="1">MDFWIVFLALILVVVSLVVVEGTHEGEGGGGDGFMKWVGRVGERHELKRKGGVVADMTWLDWKSKQVTSKSYIVVDQNGGGDFRTITEAVDSIQRDMFRPYRITVQINSGFYREKVIIPKNKPMITLLGVGGPIVDWNDTAFVTQNSTLDSATVGISGNNFMARNITFQNSAPGPPVGAVRRQAVALRVTSDIAAFYECAFLGYQDTLYDHRGRHYFKNCFIQGNIDFIFGDGLSIYKECTINVVSDGSGSVTAQKRQRTDENTGFSFVQCSVVGSGHVYLGRAWGPYSRVVFSFTYMADVVDTRGWMDWGIPERQQTVYYGEYRCTGPGSVSYGRVPWSRELTDADAAPFVSLSFIDGESWVPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTJ3</accession>
    <name>A0A8T0GTJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G099900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTJ3"/>
    <dbReference type="OrthoDB" id="206354at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019369">
        <property type="entry name" value="Efm5/EEF1AKMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200:SF0">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="198" mass="22936" checksum="6C2025B720CAE95B" modified="2022-10-12" version="1">MAMVASTEKPGSSSSNVRHMFNDGFVERHDLEQYFWTTTTVSNLRRALSCDPNLCCLATPSLAHAFHVEEPKQEVRLLDIDTRFSYLPGFRFWDIRRPEPLGESETFRVVVFDPPFFYIPMAELYRAVLEVCKGDTKTKLLIGFLVREQASLLEVFKEFGLVRTKFVLEYAAVKSNKWRNYALYSNVDLPGIKRIRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTW1</accession>
    <name>A0A8T0GTW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Carbamoyl phosphate synthase small chain, chloroplastic</fullName>
            <ecNumber evidence="4">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Carbamoyl phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_9G037900</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Small subunit of the arginine-specific carbamoyl phosphate synthase (CPSase). CPSase catalyzes the formation of carbamoyl phosphate from the ammonia moiety of glutamine, carbonate, and phosphate donated by ATP, the first step of the arginine biosynthetic pathway. The small subunit (glutamine amidotransferase) binds and cleaves glutamine to supply the large subunit with the substrate ammonia.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-glutamine + H2O = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterodimer composed of 2 chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005951">
        <property type="term" value="C:carbamoyl-phosphate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.20:FF:000001">
        <property type="entry name" value="Carbamoyl-phosphate synthase small chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000034">
        <property type="entry name" value="carbamoyl-phosphate synthase small chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="entry name" value="Carbamoyl-phosphate synthase small subunit, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009475">
        <property type="entry name" value="PRK12838.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF4">
        <property type="entry name" value="CARBAMOYL-PHOSPHATE SYNTHASE ARGININE-SPECIFIC SMALL CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405">
        <property type="entry name" value="CARBAMOYLTRANSFERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="Carbamoyl phosphate synthetase, small subunit N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carbamoyl-phosphate synthase small subunit N-terminal" evidence="18">
        <location>
            <begin position="86"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="433"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00044031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00074572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00083899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0561108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="51234" checksum="B557C53D9D63F916" modified="2022-10-12" version="1">MAMAMGMQVGVGLAPPALVQGVAAQRGESVSSLHFAGSSICGRLQAAPVAVVSVRAERASSVQVSCGGAAVVDGSAVTAARPWKTSDCRLVLEDGSVWRGKSFGATGTQVGEVVFNTSLTGYQEILTDPSYAGQFVLMTQPHIGNTGINLDDEESGQCFTGALIIRSLSNMVSNWRSSETLPEYLAKRNVMGISDIDTRAITRRLREDGSLIGVLTTDKSKTDDELIEMSKNWKIVGKDLITDSSCKEPYEWKDKTGGEWEFSTTIPNGDAEKFHVVAYDFGIKQNILRRLTSYGCKITVVPSTHPSSEVLKLNPDGVLFSNGPGDPSAVPYAVKSVQDLVGKIPVFGICMGHQLLGQALGGTTFKMKFGHHGGNHPVRHLPTGRVEISAQNHNYAVDPATLPEGVEVTHVNLNDGTCAGLTFPAMKAMSIQYHPEASPGPHDSDQGTSHSQSFKLGSSTTYFCFGDDHGYVSFYHRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVN3</accession>
    <name>A0A8T0GVN3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G142400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035824928" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7917" checksum="7A5750ECB090664B" modified="2022-10-12" version="1">MLCLGMHWFLCQALVCACSVVLLYPSVLEASRFYVWRLRTDASSFLFSNFHFAVFETDSCRRGYHGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVU3</accession>
    <name>A0A8T0GVU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G066100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04051">
        <property type="entry name" value="C2_SRC2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044750">
        <property type="entry name" value="C2_SRC2/BAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246:SF173">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32246">
        <property type="entry name" value="INGRESSION PROTEIN FIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="24898" checksum="7D6D2872294987FE" modified="2022-10-12" version="1">MAHRELQVTVISAQDLKNVRLSGRAMSPYAEVWIRSSGVSKVQTGVDSGGGINPSWNSVVKVPCEEELFRSDGAVTIALRHRGSICDKLIGTVTVPLSDLSLQCRAADSNASRESTLMTYQVRMRSGKPHGVLNISVLVGSLVKQASYDKPSVAHPSETAPPVTAYPTSTTGYRQAAVTPPNVTQYYPPQQVYPPQQSAYPLQHNLHPPQYQPQYAQPAGYNYQQVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW67</accession>
    <name>A0A8T0GW67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">60S acidic ribosomal protein P0</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G140900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Ribosomal protein P0 is the functional equivalent of E.coli protein L10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW67"/>
    <dbReference type="OrthoDB" id="10259902at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05795">
        <property type="entry name" value="Ribosomal_P0_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.105.20:FF:000001">
        <property type="entry name" value="60S acidic ribosomal protein P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050323">
        <property type="entry name" value="Ribosomal_protein_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_uL10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="Ribosomal_uL10-like_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="Ribosomal_uL10-like_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_uL10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030670">
        <property type="entry name" value="uL10_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699">
        <property type="entry name" value="60S ACIDIC RIBOSOMAL PROTEIN P0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45699:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00428">
        <property type="entry name" value="Ribosomal_60s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039087">
        <property type="entry name" value="L10E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="Ribosomal protein L10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL10-like insertion" evidence="7">
        <location>
            <begin position="114"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="284"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="284"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR039087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0562374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="34407" checksum="5F350A539A5570C9" modified="2022-10-12" version="1">MGFKGTKAEKKILYDKKLVELLDEYTQVLICAADNVGSKQLQGIRQGLRPDSVVLMGKNTMMKRSIRIHAEKTGNKDYENLLPALVGNVGLIFTKGDLKEVREEISKYKVGAPARVGLVAPIDVVVPPGNTGLDPSQTSFFQVLNIPTKINKGTVEIIAPVELVHKGDKVGSSEAALLAKLGIRPFSYGLIVVNIYDNGSVFAPQVLDMTEDDLLEKFAAGVSTVAAISLALNYPTLAAVPHSFVNAYKNLLAIAVETEYSFPLAEKTKEYLKDPSKFAVAAAPASSTESAAAPEAAKVEEKVEEKEESDDDMGFSLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXP2</accession>
    <name>A0A8T0GXP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyrrolo-quinoline quinone repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G179500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyrroloquinoline quinone</name>
            <dbReference type="ChEBI" id="CHEBI:58442"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial PQQ dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.140.10.10">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_b-propeller_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_rpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32303:SF10">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN ASSEMBLY FACTOR BAMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32303">
        <property type="entry name" value="QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770954" description="Pyrrolo-quinoline quinone repeat domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Pyrrolo-quinoline quinone repeat" evidence="5">
        <location>
            <begin position="59"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0562884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="42911" checksum="0C0399CA771C90E0" modified="2022-10-12" version="1">MAANGALACLLLTTLYWTSCLAFESFAQAKWPNHGGGIENLRVARPGGNLSPSTVANLKTKWRVKTTGDVTATPAIANGMVYFPTWDGELFAVKEKDGSILWRKNLTEVVGGSKTIITSRATPVVENKYLLVGFYGPALLIALHIQTGKLLWSTFLDANPYAVITMSGTVYESEYYVGISSISEAVVDEPCCTFQGSMVKVDIKTGKIKWRTKMVPDNGNKIGLYSGAAIWGSSPPIDCKRRMIYIATGNLYSTPPDVTECEAKQENKTVRDIPDPCISPDDHSESILALNLDSGRVVWAHQLGGYDTWVLSCFNTNGPQPNCPPIVGPDYDFAEAPMMLTTLIQTNMVAVGLMLSLLDKRVALFGLSSVIMELLCGIRYLDREVQQEDQCGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYG3</accession>
    <name>A0A8T0GYG3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G008500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYG3"/>
    <dbReference type="OrthoDB" id="998354at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6277" checksum="C466C7876BA5DD08" modified="2022-10-12" version="1">MQVCERLGPSLYDFLRKNNYRPFSADFVRDVGRQLLESLACESFSCMSLDELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYK2</accession>
    <name>A0A8T0GYK2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G048200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYK2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd16272">
        <property type="entry name" value="RNaseZ_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46504:SF2">
        <property type="entry name" value="TRNASE Z TRZ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="1">
        <location>
            <begin position="169"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="43958" checksum="CA08D16B1074EEDD" modified="2022-10-12" version="1">MHSALHFRNGTSALAQRFFTAHNGSHFKGSVSTLITTRGPGQSSFISMSSDSTATGTWCRFPVSSGRRFEAMASDVVAEVENAGDEGVELGVCESSPFLLAPEERPVCKKIEPGNGYGQTKLGRPTTGALDVDGFSIEGVSVGGQETCVMLPAMKIAFDIGRCPKRAIDQDFLFITHAHMDHIGGLTMYVACRAILKRKVPTVIVPACVKATVEKLFAVQRELDNSPLPVNLIGMDVGDEFDLGRGFIVKAFKTYHVVPSQGYVIYSVKQKLKQEYVGLPGTEIKTLRASGVQITESVRTPEAAFTGDTTSDFFLDEANMDILNAKLLIMESTFLDSNVSPANANEYGHMHLSEIVAHAEKFKNKSIVLIHFSARYTHENIFDAMKKLPPPLQGRVFPLTEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0P1</accession>
    <name>A0A8T0H0P1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ERCC4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G192500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the XPF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0P1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000110">
        <property type="term" value="C:nucleotide-excision repair factor 1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901255">
        <property type="term" value="P:nucleotide-excision repair involved in interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd20078">
        <property type="entry name" value="XPF_nuclease_XPF_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000038">
        <property type="entry name" value="DNA repair endonuclease UVH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10130:FF:000002">
        <property type="entry name" value="DNA repair endonuclease XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047520">
        <property type="entry name" value="XPF_nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10150:SF0">
        <property type="entry name" value="DNA REPAIR ENDONUCLEASE XPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="Restriction endonuclease-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="RuvA domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="11">
        <location>
            <begin position="798"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="338"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="575"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="358"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="582"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="615"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0565466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1029" mass="114678" checksum="187577284B6A1E56" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H148</accession>
    <name>A0A8T0H148_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G002200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H148"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770210" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="102" mass="10940" checksum="82F146C46018D09E" modified="2022-10-12" version="1">MMPVPLLVVVGLTSGSGRAGAEVKLRLCCTCAGGGCRGRKLTKDLRVTRPTTCVGLSGDKEVIERCKEEKSKPAGLRRRVGSNRKCVKVLDPATRLLCERVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1R5</accession>
    <name>A0A8T0H1R5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G076400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="369" mass="40029" checksum="DB4BD0DA01FA754E" modified="2022-10-12" version="1">MAMSLGLEKLSFVCFEARGDGRLVSVCKERFGAGVLVGGIGQNRRCFGEFVGGRVSREGVVLKSLGGVGGRASRVGRLVSESLPVADEHREVEGEVGGLNPKGEDSGDGDEEPTASPAPWMSEEEAKAVVSEVILNGDDLRVIEYPAKEDVQPEDTHPLNSLADSFLNKINGDGDGRGFSLTDVGGVWKTGEDAGELEVPELSISGFDVKEGVSPLAQWTSTELTMQHTQLARIVTDVYYMQFAFAFFGGVRVVEALLSVYSTSPPDFGKFKELLNALDPFTISWLANNVREPLSTLMEADPMDLEKVVSLKSNVWTAVHAFYERQWKVMATLALARSLSLIASHEPTAKAVTDKVQWLWNALMALPVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2P6</accession>
    <name>A0A8T0H2P6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dof-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G042600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2P6"/>
    <dbReference type="OrthoDB" id="10501653at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045174">
        <property type="entry name" value="Dof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003851">
        <property type="entry name" value="Znf_Dof"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089">
        <property type="entry name" value="CYCLIC DOF FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089:SF22">
        <property type="entry name" value="CYCLIC DOF FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02701">
        <property type="entry name" value="Zn_ribbon_Dof"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01361">
        <property type="entry name" value="ZF_DOF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50884">
        <property type="entry name" value="ZF_DOF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Dof-type" evidence="9">
        <location>
            <begin position="68"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="109"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="298"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="350"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="388"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0566156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="414" mass="44914" checksum="A2FCFE98C7B65F45" modified="2022-10-12" version="1">MHLPLAHQARLAGQFEDENEEIHAQLHANSVSHSHDDDGSQSQGSKGSGGGVGADGNDGSLTKPPKDLPCPRCQSMNTKFCYYNNYSVNQPRHFCRNCQRYWTVGGTLRNVPVGGGSRKKTRTRSRSDPYYRPGNVNSPAQDHSSDAETEAPMHPAMAMESMEAMAAMAAMMGMAGPEMAGLDGALGGFEDAMPDFPFHPSQLSAMLQLTLMQNAGMYSQFMDRPPFPVGAPEEAAEFQALYEAQSANSGFLSSAAAMMFMPQLEPAHLDLMHKATLWAEAQRLQAVARRQSQAQAASAWASSAEERECKPQQASTHMPHRQHAAMEELLQRQQASAGRHHRPGFWETALMHSRPSKRVPGWSEPKPSSTTHGSASTVEEEAGNPANGSYSHGGYDDSSSWGSGMPGASDLYYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3S4</accession>
    <name>A0A8T0H3S4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G154800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3S4"/>
    <dbReference type="OrthoDB" id="1700726at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF33">
        <property type="entry name" value="AMP-BINDING DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="114"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0564989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="706" mass="77454" checksum="A559729354AD441A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3Y1</accession>
    <name>A0A8T0H3Y1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pectinesterase inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G059400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3Y1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004857">
        <property type="term" value="F:enzyme inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15798">
        <property type="entry name" value="PMEI-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.40">
        <property type="entry name" value="Invertase/pectin methylesterase inhibitor family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035513">
        <property type="entry name" value="Invertase/methylesterase_inhib"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006501">
        <property type="entry name" value="Pectinesterase_inhib_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051955">
        <property type="entry name" value="PME_Inhibitor"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01614">
        <property type="entry name" value="PME_inhib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31080:SF296">
        <property type="entry name" value="OS05G0360900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31080">
        <property type="entry name" value="PECTINESTERASE INHIBITOR-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04043">
        <property type="entry name" value="PMEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00856">
        <property type="entry name" value="PMEI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101148">
        <property type="entry name" value="Plant invertase/pectin methylesterase inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase inhibitor" evidence="4">
        <location>
            <begin position="154"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="66"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0563792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="340" mass="36320" checksum="628F316569B85288" modified="2022-10-12" version="1">MMRLDDSREAGLLNRSTEYSSLEMQMSEFDVPMSRRPKGRARCYGVSACIVIIAVVAIVSVAVAGGKSSGSGDDSTEAEMRKQHANYAPAPSPEESSFPGGGWASSPPAPPLSGSTEPIASPLSPLEASPSMEAPPSLESPIPAFAPGPYSSGYHLMRYETICTKTIDPAVCLKLFASNLNSNKVDLQQWTIMTMEASQKALNESYNLAMGLTDKNPDNVALKQCIDVFGMAMEEVESSMFIVADIDVHNPGPAASDVAVSLTAAATDHDTCQEGIDEVGPFDGSDTITGDRAQHVDTLLSIALTFVDNLAIGDSNHHRRLLNIESSQRLVRLFPGKRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5E1</accession>
    <name>A0A8T0H5E1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G029200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5E1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="219"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="283"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="345"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="48568" checksum="B23A5E6AF14DF586" modified="2022-10-12" version="1">MMARSDDLGKGETSPKRPGSMENSVKSDRAEKKPRLSKLNSKSSRKRAWSEVEETDIGLEESEDPSTSRKIIRVGSTKKNDGEGDKLVERYGSRESKESESNIEESGSKLGKMKPQLSLRKWKRMSRCADTGGLEHDDGSSARSSRVDEEKIGKQKEIREHEVVRKVLQTVHLEESCGAGDNETVADREDDSIGLEKDSDGTVSSLKQSGRDKKRRGSGKADAKQPEKKLRIDDAVAEPSSRGAEQGVGVGIDNIGTWRRLKGQKPKPRPAASEDMGVSVSEAWKRLREEKDTGTSGSSVNGRSDSDLSMHSSDSELELEERAKKARYDLPLPPQGKKWTRKSREKKESSSSKRLREGGLESSGSSGSDISYSSYYHNRKWKRPRFEYMMSMQGRSWRKQARDVDDARVSCRENDRKRVQVDASEKPAKRQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5M5</accession>
    <name>A0A8T0H5M5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rab escort protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G191800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the Rab GDI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5M5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005092">
        <property type="term" value="F:GDP-dissociation inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007264">
        <property type="term" value="P:small GTPase-mediated signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.405.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.519.10">
        <property type="entry name" value="Guanine Nucleotide Dissociation Inhibitor, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018203">
        <property type="entry name" value="GDP_dissociation_inhibitor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001738">
        <property type="entry name" value="Rab_escort"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054420">
        <property type="entry name" value="RAE1_2_domI_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787:SF4">
        <property type="entry name" value="CHM, RAB ESCORT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11787">
        <property type="entry name" value="RAB GDP-DISSOCIATION INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00996">
        <property type="entry name" value="GDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22603">
        <property type="entry name" value="RAE1_2_domI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016550">
        <property type="entry name" value="Rab_ger_ger_transf_A_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00891">
        <property type="entry name" value="RABGDIREP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RAE1/2" evidence="7">
        <location>
            <begin position="392"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="348"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="350"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0565458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="563" mass="60978" checksum="5C3C161EA1F57E12" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5Z7</accession>
    <name>A0A8T0H5Z7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G045000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5Z7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14079" checksum="5D40CD4C51C6295C" modified="2022-10-12" version="1">MCACGRINQPRPPPHNIPPKEVPVQLTTVVSSQTMEQGIIPHRYHSSTEFHRYPPISVGCSTPRLDQLHEVTMPWPLRSSQQRHTVGTRPAPASACLPQLLAPRTHSSQMRTFKYACLGVSPLPIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6J7</accession>
    <name>A0A8T0H6J7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G100100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6J7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="12172" checksum="E22142F60A0E4F27" modified="2022-10-12" version="1">MQEAEPLPWFYTCSAILLPRLTRLLMCLHSLLYRGYSCASFARPRLPINLFRRLHMYTRCRFSSCLRTDTFPETCSSLILSLPDHIHPPRLDNYEARPHCERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6Y5</accession>
    <name>A0A8T0H6Y5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G071600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10446" checksum="BDB6264A3374523A" modified="2022-10-12" version="1">MLQMPRGWSNNVLDMLAQHYDQSSVPESLVISYAPKIRAHYLQYNKSNCFTRTSSSPSQHPASHNHRKNPSLFKNTPPQRYHKFVSHLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9T0</accession>
    <name>A0A8T0H9T0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRELI/MSF1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G035600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9T0"/>
    <dbReference type="OrthoDB" id="407630at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005758">
        <property type="term" value="C:mitochondrial intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006797">
        <property type="entry name" value="PRELI/MSF1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037365">
        <property type="entry name" value="Slowmo/Ups"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11158">
        <property type="entry name" value="MSF1/PX19 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04707">
        <property type="entry name" value="PRELI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50904">
        <property type="entry name" value="PRELI_MSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRELI/MSF1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="25226" checksum="7A50A026B1B95DBE" modified="2022-10-12" version="1">MVAGYVQEHIYRHPWERVTAANWKKYADPEHRPLLSHVVDVNIVNRSVDQEGGQLLTTRSIIVNAPGPWWLQRLMGTNVCQCLEESIVDNGKRTLEMVTRNVTLKDFVDVEEKCSYLPHPENSEWTLFRQETNITCASMPALKSMAAKIEQKCAEKFQQNSVRGREVLEFVCKSLERAETAAAPPAKPQLVVNTQQSSNIHSHSYSKWRTFERAEFVGATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBB9</accession>
    <name>A0A8T0HBB9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G068400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035852318" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5519" checksum="CDF2CB54B23C18EB" modified="2022-10-12" version="1">MGLGFCSLRITLSSLLGFVFRLELDFLLIPCAHHSIDRIIMNLGSPRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBN2</accession>
    <name>A0A8T0HBN2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G, chloroplastic</fullName>
            <shortName evidence="6">cEF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G185500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Chloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Plastid</location>
            <location evidence="6">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBN2"/>
    <dbReference type="OrthoDB" id="198619at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032790">
        <property type="term" value="P:ribosome disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01886">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04088">
        <property type="entry name" value="EFG_mtEFG_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000006">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000003">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000001">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000029">
        <property type="entry name" value="Elongation factor G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03063">
        <property type="entry name" value="EF_G_plantC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030848">
        <property type="entry name" value="EF_G_plantC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047872">
        <property type="entry name" value="EFG_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009381">
        <property type="entry name" value="PRK12740.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261:SF1">
        <property type="entry name" value="RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43261">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR G-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="97"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="170"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="224"/>
            <end position="227"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0568087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="786" mass="86103" checksum="44AD65C7E0139AB3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCJ3</accession>
    <name>A0A8T0HCJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G034700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="18930" checksum="E64536E6DE812680" modified="2022-10-12" version="1">MIIIPAAEQAPSAHATRHCRTCRSKGASQGVELLGVELRFTHQLHCSAAALGPGCSLLCRAVTSFSKVPTRLDSSTGVRHHSDRLHSMIHSSPGSLTLRDEFSSHCQHGFCTAASSLITQGTKLSPSSKCATVAVASERLETGYVTVVCELRVVSFELEVFPKLENRTELKLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCQ1</accession>
    <name>A0A8T0HCQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_6G079000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCQ1"/>
    <dbReference type="OrthoDB" id="415460at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF10">
        <property type="entry name" value="SLOWPOKE 2, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01449">
        <property type="entry name" value="BKCHANNELA"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00169">
        <property type="entry name" value="KCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="250"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="13">
        <location>
            <begin position="132"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="363"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="14">
        <location>
            <begin position="505"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="820"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0569273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1117" mass="125360" checksum="9FA2AAAFBF6A67FF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD06</accession>
    <name>A0A8T0HD06_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NIF system FeS cluster assembly NifU C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G104800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer; disulfide-linked.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD06"/>
    <dbReference type="OrthoDB" id="565552at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.130:FF:000003">
        <property type="entry name" value="NifU-like protein 3, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="entry name" value="Fe-S cluster assembly (FSCA)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178">
        <property type="entry name" value="IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11178:SF25">
        <property type="entry name" value="NIFU-LIKE PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="Fe-S cluster assembly (FSCA) domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035888421" description="NIF system FeS cluster assembly NifU C-terminal domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="4">
        <location>
            <begin position="101"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="NIF system FeS cluster assembly NifU C-terminal" evidence="4">
        <location>
            <begin position="182"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="246" mass="26027" checksum="1047A050FE99CEC2" modified="2022-10-12" version="1">MASALLMQAHAVAVLGARAGHGEASCSYQDVPVLTRRGGGRGSEGVNLRGDRFGLRRGSVAAAFGLRSSGGSRQAGFRGRVEAVATEDVLTEGLELTEENVELVLDEVRPYLISDGGNVALHEIDGLVVKLKLQGACGSCPSSTMTMRMGIERRLIERIPEIQAVEQIMDEETGLALTEENVDAVLSEIRPYLVGTGGGELELVKIDGPVVKVRLGGPAASVMTVRVAVTQKLREKIPMIAAVQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDS8</accession>
    <name>A0A8T0HDS8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">KC19_6G031400</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="24 25" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="24 25">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551849at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033612">
        <property type="term" value="F:receptor serine/threonine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000784">
        <property type="entry name" value="leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000129">
        <property type="entry name" value="Leucine-rich repeat receptor-like kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000221">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase PXL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000233">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase TDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000526">
        <property type="entry name" value="serine/threonine-protein kinase BRI1-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000150">
        <property type="entry name" value="serine/threonine-protein kinase BRI1-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF58">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR PROTEIN KINASE MSP1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="18"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="15 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9 22" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035881787" description="non-specific serine/threonine protein kinase" evidence="22">
        <location>
            <begin position="23"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="972"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="1063"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="1092"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0568588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1344" mass="145480" checksum="38E9F07F795A5B18" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEX9</accession>
    <name>A0A8T0HEX9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LRAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G045200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEX9"/>
    <dbReference type="OrthoDB" id="421951at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.10">
        <property type="entry name" value="endopeptidase domain like (from Nostoc punctiforme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007053">
        <property type="entry name" value="LRAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46137">
        <property type="entry name" value="OS05G0310600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46137:SF4">
        <property type="entry name" value="PROTEIN LEAD-SENSITIVE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04970">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51934">
        <property type="entry name" value="LRAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LRAT" evidence="1">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="20059" checksum="86D80144660A6BA0" modified="2022-10-12" version="1">MGLLGFHTMKIKEEELLAGDHIYTDRNQHTYYHHGIFIGDDRVIHFTKVSSDYPAVPEEKCDHHSNTTRDTESGVRMSCVLKCFLQPGHSLYRFVYDEGLLAIVRSTRSARHCTRVESVLRRANEELEEDTFGGSSLILKNCETFAYFCKTGVKFHLSKQVLRSLGFLVLAAAIMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFT7</accession>
    <name>A0A8T0HFT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G084300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFT7"/>
    <dbReference type="OrthoDB" id="10264121at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00498">
        <property type="entry name" value="Hsp33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.30.10">
        <property type="entry name" value="Hsp33 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1280.10">
        <property type="entry name" value="HSP33 redox switch-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000397">
        <property type="entry name" value="Heat_shock_Hsp33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016154">
        <property type="entry name" value="Heat_shock_Hsp33_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016153">
        <property type="entry name" value="Heat_shock_Hsp33_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111">
        <property type="entry name" value="33 KDA CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30111:SF1">
        <property type="entry name" value="33 KDA CHAPERONIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01430">
        <property type="entry name" value="HSP33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64397">
        <property type="entry name" value="Hsp33 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118352">
        <property type="entry name" value="HSP33 redox switch-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035772051" evidence="6">
        <location>
            <begin position="23"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0569348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="41440" checksum="89C1E83622B90667" modified="2022-10-12" version="1">MTTAVLSHRLAAFATVLSCARGEELRGVLSGGSLLCRSFAVRGVRGGFSRLGRSECRIAGRIAPVLVSKQRRLISKDAVRARALENGSDAELDPREGGDKLVRVISKDAEVSVLSLVATEVVREAQQRHSTSPIAIAALGRTLMGTLLLGALKGDAETVQVVFLGDGPLGQMTAISSDGGYVKGFVGNPLCDALYKENGKLSVGLAVGSGVLSVVRNNRKWKQPYTGTIPIYSGEVAEDIAHYLADSEQMNTALGLGVGFDKEVGIKFAGGFLVQILPFCSDETLAKLEENILKMKPLAEAPSDCKASDIVEAILDGIGVGDYNNGIIPRYGPCGVELLKPRMMRAVASLGPVEVQQILDEQGSVEVRCEYCGDVAQFSEADLQQVLQSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGD0</accession>
    <name>A0A8T0HGD0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G135200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000005">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002229">
        <property type="entry name" value="RhesusRHD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00342">
        <property type="entry name" value="RHESUSRHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="35"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0570045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="500" mass="54124" checksum="EF2E40A5DC1BB2D8" modified="2022-10-12" version="1">MAFALPPTLPGSVPSAYINDGFGANPEWLNKGDNAWQLAAATLVGIQSMPGLVILYGSIVKKKWAVNSAFMALYAFAATWLCWVLWAYEMSFGEQLVPIWGKAGSALGYKFLLSQATLPATAHYHRNGTLETPALDAHFGMADMVLFQFFFAALTLIMLAGSVLGRMSFRAWMLFVPLWLTFSYTVGAFSMWGGGFMWQWGVLDYAGGYVIHVSSGVAGFVAAYWVGPRLPKDRERFPPNNMLLVLTGAGLLWLGWSGFNGGAAFSAHVVAGLAVLNTHVCAATSLLTWTTLDVFFFGKPSVIGAVQGMMTGLVVITPAAGLVPGWTAMIMGVLAGSIPWWTMMVLHKRWWVLQKVDDTLGVIHTHGVGGVLGGICVGLFAEPTLCNYLDVPVKNSNGVFYGGNGGVQLVKQIVGALYIAGWNLVITTLILFVIGLITPLRMSEEHLLVGDDAEHGEEAYALWGDGEKFDITRHPTTTIAGDIEQRNPTSYADRQMTLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH05</accession>
    <name>A0A8T0HH05_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G157300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant LTP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043325">
        <property type="entry name" value="LTSS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000528">
        <property type="entry name" value="Plant_nsLTP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33044">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR/LIPID-TRANSFER PROTEIN/SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00382">
        <property type="entry name" value="LIPIDTRNSFER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00499">
        <property type="entry name" value="AAI"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274504" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="245"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="309" mass="30834" checksum="4BBA712E39BE5E02" modified="2022-10-12" version="1">MAARRAMAGAVLAMAVALLAMGANAEVDCSTQLNAMQPCIEYVNSNTSAPPSKPCCTAFNTTQVTMPVCLCQLQQAFSDPATAPGNVTRANEIPSLCAVAVDPSRCPALLGLAPAVAPAVAPAVAPVASPRISPIATPTVAPVGPSPAGADVDCSAEFASLSDCITYVSSNTSTTPPATCCSALLSVHTNKPVCLCQLLQLANDPAQTPAGLNVTKALELPTSCKVNGADVDNCPALLGQPVASPVESPLTAPVPESSPTPEAGAPGVDAGTPAPEATPAVSEPTGNNAATTAASMLLGFTALTLHFFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL59</accession>
    <name>A0A8T0HL59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG011900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000062">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A regulatory subunit A alpha isoform"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054573">
        <property type="entry name" value="PP2A/SF3B1-like_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051023">
        <property type="entry name" value="PP2A_Regulatory_Subunit_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648:SF4">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10648">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22646">
        <property type="entry name" value="PPP2R1A-like_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="10"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="203"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="242"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like HEAT repeat" evidence="4">
        <location>
            <begin position="274"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="281"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="320"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="359"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="476"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="515"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="3">
        <location>
            <begin position="554"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="586" mass="65157" checksum="0F73E50131AA4FD4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNJ2</accession>
    <name>A0A8T0HNJ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG089600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="128"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="31914" checksum="90A1E0DB39ABA3F0" modified="2022-10-12" version="1">MSDSSLSPVSSPSGEDAGNIAQGDPAADEGRSEANADATLDNNREEIIASAHGSRHAEDISNQNVISTGFTANKVDCCVCVKGAGEGKGRRPVPSWSALKFHAETMNRMLLTRHRYAVLRAGQDVIDLTNDNGPDNVTTDSSAKNNEASDGLQELAPAGSSEALCNESNTVPKRPREIPMFPDFRSVPVPRFTPLQKWEFLNGLPVDGVEDVEKWAVDVGLLEEDPDSSDPKKKRKTMAGLEPPKYGTSSRTFEIEACLEEETNANDAEEKKDDEVHASTSSRKGKEKEDNLNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNW5</accession>
    <name>A0A8T0HNW5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG082500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="7091" checksum="AC07FD71B2EE540E" modified="2022-10-12" version="1">MSSKSLLAVTFICLTYREPGHLFQAWLWVFLKLVERLTWTIHMTCCFSTWFSLSELLASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPI4</accession>
    <name>A0A8T0HPI4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG115100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPI4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032378">
        <property type="entry name" value="ZC3H15/TMA46_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681:SF0">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12681">
        <property type="entry name" value="ZINC FINGER-CONTAINING PROTEIN P48ZNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16543">
        <property type="entry name" value="DFRP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="6">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="106"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="176"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0572665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="374" mass="42281" checksum="7A9B076587829607" modified="2022-10-12" version="1">MPPKAAPKAAPKAGGKEKTKADLAKKQKLVEDKTFGLKNKNKSKNVQKYVQSLHQSVQNAGPKRGSAEDVKAQAKKKKEEEAARDKELNELFKVAISQPKVPLGVDPKSVVCEFFRHGQCAKGFKCKYSHDLSVERKGEKIDIYSDQRDDETMDEWDQETLEKAVAAKANEYNNNKPTEIVCKHFLDAVERKQYGWFWTCPNGGKDCHYRHALPPGYVLKSQMKALLEEEGEKLTIEEEIENQRHMTKTTTPMTAELFADWKRKKAEAREADLSAKRAERARTDRMSGRELFLSNASLFVDDAEAYDIYIREEEPDAVEASGSAQKVEEKASTSERAGISEQDEKLFADDDDELDLSELDELDSSIHKTSLDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPK3</accession>
    <name>A0A8T0HPK3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG127400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="9478" checksum="A29F715C0B47BD4A" modified="2022-10-12" version="1">MEAIDMVLCLWHQSSTAHSDSVSTGGFQQCDLYVSCEPCIMCASALSLLGFREVYYGCGNDRFGGCGSVLDIRTDGCAPCGSRYSLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS03</accession>
    <name>A0A8T0HS03_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG187400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035745899" evidence="1">
        <location>
            <begin position="23"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7062" checksum="28DA93D3D6A3BB1E" modified="2022-10-12" version="1">MSSKNSRSLALVFVVLIEKALQVFVLDKQSPPYPPQSFEAEILINCVTHNNQLSHPKLVSELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSS0</accession>
    <name>A0A8T0HSS0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG210200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48258">
        <property type="entry name" value="DUF4218 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="240" mass="27763" checksum="50FCB1FDD6D23ABD" modified="2022-10-12" version="1">MEERALLRGQNPRRLLSFADWIEDRVRLMGFNGENPSADLVTMSRLPSPLVKHHNLMWSFGYHFRTDEEDGRQHVSFDSGVAAIITQTYRLSRLDLNLIEVDLQYVGIIKDIMQVNYGHLKFNVLKCSWIKPDLEGEPTIREDKDGFWLVKHGARQSLDVEPYLMAAHARQKVVRYKEPRSCRVTDGIREATLSAPGRNSATHLRTATKVEVEMPPPAREPVQYPEEKIRDFVLCARKMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTG1</accession>
    <name>A0A8T0HTG1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG230800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10979" checksum="EE055764C1233558" modified="2022-10-12" version="1" fragment="single">FHTAKDLPHAPTASLNLTPAPRTPPELQCTSRAEAHSTPPRQHSSAENGLAGIHPFTRTQAPMEPARGSVRAARTREMRQGAGTNRRDARPRGRSSKRCPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV88</accession>
    <name>A0A8T0HV88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG284200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="290" mass="31717" checksum="0DA8EC4BF9585A75" modified="2022-10-12" version="1">MLHTEGARIQPTGDETNLVQGAIRVFDEHINAVVTIKKTISYCSYNLHQPLAAHRRSQSSCPTTTAKQQHERANCSVQHHRSSSLNIDTEAETEVSAAGAAREMVAIEAVDVGSAREVDFQASVAIRPANYTCYHRNQQATPNGGTTLKPLATRQQEIHYKVSILILLLKGKCPPTATLDEGGSRRKSTSAMGEELSITLATSVELFIPMTKVERLSTKDELLLAKADLSKKEEDLLKTRAELLRKTAENTPSILTERGASTEVQAHCGAVCSKWLGKTNRPQTRKGKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX22</accession>
    <name>A0A8T0HX22_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG333000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15202" checksum="8A852AC9A32E6407" modified="2022-10-12" version="1">MTETLLILTSIASGGLLLLQRRSPNSIFNNLRVSTLSLPPRTKTFLNEILKMVVMHALKLSSVSLPIIHITHSHSADLNFDIEILESTLDNSEELTERTTDDSTIFQIGRRDIHLQCRLLLQNYETYPLSLSADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1A5</accession>
    <name>A0A8T0I1A5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutaredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3 9">1.11.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G116800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62624"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:10730"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.25" evidence="3 9"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1A5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF8">
        <property type="entry name" value="PEROXIREDOXIN-2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="126"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0576906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="290" mass="32109" checksum="0DEAC65F2BBAB72F" modified="2022-10-12" version="1">MVENRKAQAPCVGDAASGSNSKIMPCPDTRPPQFKPLTCDTDDEKNFPFVEVLGPDKTAKRFALGTRASFAVERFNKKLVDAVRPVVCVQAYKEGEDPVEFGPDAPLISKCTWDLRVVQEAPFEPIGVGDKIPNGELSYLDDDGKLQAHCIHDLVREKRVVIFGIPGAFTPTCSVKHVPGFLQRAEEIMDRGVKEIICVTVNDPFVVKEWEKTFPNNKHIKFLCDGSATWTKKIGLELDLIDRGMGIRSRRYCLLVDDTVVKIANIEEAGGLEVSTADRIMQDLETSKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I513</accession>
    <name>A0A8T0I513_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G003100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I513"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056158">
        <property type="entry name" value="Beta-prop_IFT121_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056157">
        <property type="entry name" value="TPR_IFT80_172_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057361">
        <property type="entry name" value="TPR_WDR35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF5">
        <property type="entry name" value="LD29485P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23390">
        <property type="entry name" value="Beta-prop_WDR35_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23387">
        <property type="entry name" value="TPR_IFT80_172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25170">
        <property type="entry name" value="TPR_WDR35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT121 second beta-propeller" evidence="5">
        <location>
            <begin position="1"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="IFT80/172/WDR35 TPR" evidence="4">
        <location>
            <begin position="271"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0578167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="555" mass="62876" checksum="A1783841ACFA335F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I633</accession>
    <name>A0A8T0I633_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G025200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I633"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000783">
        <property type="term" value="C:nuclear telomere cap complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098505">
        <property type="term" value="F:G-rich strand telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032210">
        <property type="term" value="P:regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04497">
        <property type="entry name" value="hPOT1_OB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057620">
        <property type="entry name" value="POT1A/B-like_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25507">
        <property type="entry name" value="OB_POT1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00976">
        <property type="entry name" value="Telo_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="5">
        <location>
            <begin position="11"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0578465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="55276" checksum="90AF79180256292C" modified="2022-10-12" version="1">MANREPEKYNYTPLADAVMCLEQKVNFYGVVAEYEQPKPTRGRDYLCTMTVIDMSYNSPGLRVLYFAPDVDMMPRVKDLGDVIRFHRVQMKSHADAPQAIGNPKKGSSFVLLRGCEGDDYVPYHKSHSNFTMEASDRNIVGLLRMWASSHPIDTLAGTNKYMKQIKDVNVDSYFDLCCKILFVNDQSAEHSVIIYVWDGTDASPACLNPLEQSENGDPGQDLWSSKELAVPVDVMRGFPALGTVLPLVPFGMPEDDFGPQLPLAGDWVKLRNIGCRVRKGLYEGVTYHGSKIGILSPSAQAVQNCERAYEERLTSEALRLPHWCPKPPQSMLVTGYDHCKLSTLREVLTYPQVTYKFRCMVRVMATWPSDVLDFCVPHDGSAAQPKDHLEQGDFVYVVRLTLEDPTARLHAFLYGQDAVEFFVGYPAANLRRQGDTVGALKRKVDRLLGVSEHGPPNPPWVTCCLKSYYLDKEHPQETRRYRVFGTRFPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6U7</accession>
    <name>A0A8T0I6U7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CAAX prenyl protease 2/Lysostaphin resistance protein A-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G081200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004175">
        <property type="term" value="F:endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080120">
        <property type="term" value="P:CAAX-box protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1/LyrA-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43592:SF4">
        <property type="entry name" value="CAAX AMINO TERMINAL PROTEASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 2/Lysostaphin resistance protein A-like" evidence="2">
        <location>
            <begin position="245"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="36887" checksum="5B5E0F97A92A340B" modified="2022-10-12" version="1">MVSRMPSMMLTAGRGCLLAGNHHGIISQRRLGMWRRQQVGFSFVSDGKASRRVCGKESHLCWCQRVDDEDHEEVDVSDVGLPAQDVPSGVGSSSQVEAFSRLPSTVPWGTGVVASTMVIFWAGFHIPLGLGGLDIVAKVIPEQFVDPQTQAVSLVFVQLLELAGTMWLIQSTLQPFGPLPDCFNFRFDEVWRNRGWLPASASGLLVLLVAVAATASVTQDVSSSEISNGSSALTTLLSSTPLARLAIYVAYCGLTPFLEEYVYRGFLLTFLGTRMRWPFAVMISALVFSISHLSPPGFLSLFWVGCCLGTAYTWNGNLATSVVIHSLYNAIVLTKALLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8P5</accession>
    <name>A0A8T0I8P5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exocyst complex component Sec8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G094800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8P5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039682">
        <property type="entry name" value="Sec8/EXOC4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14146:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="22608" checksum="FF5315DF2CF24CFB" modified="2022-10-12" version="1">MNSALTSGLGILAEKYRLLSSECLRTLRVEMQLVSIFHLQSMGGRDYLREQDAEEPEDFIVALTSQIQRIAEEMAAYMPSLKRSYIFGGICSVSAAAFIKAVTNMEAINMLGVRQVNRNCIALQQALASLVASSGEFLEERLDRVRTYYDLLTIPFEALIALVPDNDAIFSLSEYTALLKVNIPGREIPTNAVQQIAMILAPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA68</accession>
    <name>A0A8T0IA68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G116500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035828535" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9334" checksum="805165DDDD375DFB" modified="2022-10-12" version="1">MAHSSFCLGLLFRFCDVRVSCCCFGGGVRICISRLVVFRMCFVIMDPCLFHELRVFWKMVEDLGCSESSIQGLLLPGFMKLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA90</accession>
    <name>A0A8T0IA90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G130000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000383">
        <property type="entry name" value="Leucine-rich repeat receptor protein kinase EMS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48065:SF75">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING N-TERMINAL PLANT-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48065">
        <property type="entry name" value="OS10G0469600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035891658" description="Leucine-rich repeat-containing N-terminal plant-type domain-containing protein" evidence="7">
        <location>
            <begin position="30"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="767"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="8">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="9">
        <location>
            <begin position="235"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0579869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="813" mass="88325" checksum="FBD16A16B515C323" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAT3</accession>
    <name>A0A8T0IAT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G144700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAT3"/>
    <dbReference type="OrthoDB" id="376357at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055572">
        <property type="entry name" value="DUF7148"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ C76, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45295:SF4">
        <property type="entry name" value="OS06G0474800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23650">
        <property type="entry name" value="DUF7148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="87"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="499" mass="54554" checksum="860D96E6E24D0218" modified="2022-10-12" version="1">MDAVVRHTVGIVLPALSPPPVAQLLGASPPSGQRLVPGKSSALGLCGGAHVAGKHGFRRGDLLVRCATGNQSRSNTMNGSSSGEMLDYYDVLGVSVNSSPAEIRKAYRMLQKKHHPDVAGEKGHAMTLLLNEAYATLMDDSLRGTYNEAHSHKAAMRAAGHTMFSGSPFSQWVGPDRPQGIFVDENVCIGCRECVYAACKTFSMDDAEGTARVTRQWGDPEPTIKQAIELCPVNCIHYVEREDLAVLEYLIRPQQKQGNGVYGGGWERPKNVFMAARTFKRQMEDKKTRATGSVMKETPAQKQARMEAEFKMKAGAFWRFWSWSAQPMPWEKGTTSSSQEYREDFEWPWKGLFGRSSTAELLTIPVPATDVSKVVSLVQDWATTFASSSEVPLPMPFRTDPLPNGIRLTLITTANGMLASAGVLVATVEEKIDTTNMESAALGEPFVTEVDAKYVLVVRREGVTGTAALPGEGRILKLMKEVVKGRDSSYSAYSIPRNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICH8</accession>
    <name>A0A8T0ICH8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G189200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICH8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46880:SF5">
        <property type="entry name" value="DUF4371 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46880">
        <property type="entry name" value="RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="924" mass="103831" checksum="6CF951D635D13872" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE12</accession>
    <name>A0A8T0IE12_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G225700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053303">
        <property type="entry name" value="Chloroplast_PPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47935">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN MRL1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47935:SF1">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN MRL1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="324"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="358"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="393"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="428"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="500"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="4">
        <location>
            <begin position="504"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="570"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="605"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="640"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="68"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="185"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="984"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="141"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="998"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1010" mass="109944" checksum="FAB938B1B3DE86F0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IET3</accession>
    <name>A0A8T0IET3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G247600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IET3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="21229" checksum="4E0AB8F0B82F023A" modified="2022-10-12" version="1">MIGPSLVLRSPQCSTGSLIASAKFKPPTYFNSGRSTSFVERHYRPRGLFLSSSVLTWSSFVAGPPSSSLLFFFSFTGLQLCSQKKFENYSCSPNSYSKVWRIVCIGISLLWLKTVGSSTKLLKLSNIFRIFYHTDCKVMHYYSQELPPQKNYTILPQNLTFSNKIITHVYMNYGREINLEFLVSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFP6</accession>
    <name>A0A8T0IFP6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G068500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8444" checksum="67FEB491C1876BE5" modified="2022-10-12" version="1">MPRGGRRGKGAAGSSFEGRDWQWRWQGECGMEARREGFGDRDGARVRGFNAAGGRERVRERRIMNACQCATRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGC3</accession>
    <name>A0A8T0IGC3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G057100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="512"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="792"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="867"/>
            <end position="1097"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="800"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="873"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="891"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1060"/>
            <end position="1076"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0582402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1415" mass="156639" checksum="F5BC0DDD6D952248" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPM5</accession>
    <name>A0A8T0IPM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutathione S-transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G217700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the GST superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd03048">
        <property type="entry name" value="GST_N_Ure2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051:SF8">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE GSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44051">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01151">
        <property type="entry name" value="Main.2:_Nu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="3">
        <location>
            <begin position="114"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="4">
        <location>
            <begin position="204"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="327" mass="37093" checksum="CA8BA5984DB1DCAE" modified="2022-10-12" version="1">MPCIWEILYRPNTGREREIKIDWSYSGFRWVIGSAIERIWFIGGYVVVMAGRVVMAGVQCLERVVVSQVGWRKLDGAMLGGRLQIREPHLGLNPGVFKGYKLNHSATRQTATMASKIQLYSMATPNGQKIGVALEEMGLKYEAHTINITKNETFTPEFIKINPNSKIPAIIDPDGPDGQPITIFESGAILLYLASKSGKFVSKNPRLKWETIQWIMWQMAGVGPMLGQFGHFYRFAKDKCKDPYPTERYANESKRLLGVLEERLKGRDFIIDDGYSIADMATFPWIRAAREHYAEKLEFDKFPLVNAWVDRCYARPASAKGTTVCKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITY0</accession>
    <name>A0A8T0ITY0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G076200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITY0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="30"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="916" mass="105164" checksum="5037992EC4078FDA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU24</accession>
    <name>A0A8T0IU24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G149300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="14046" checksum="42D2306049928AA0" modified="2022-10-12" version="1">MLSLSGSGLSESRTMRGRLTGTIYKQDSRDLMPHIVRKTKITTTLFIYYFERPVLLVYSDTLCFHKASVSIFYLFSYIALSTGLVSSSCQVILTQMLEMLLSHGFLHVNHFLRLQSRSGLCLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVE3</accession>
    <name>A0A8T0IVE3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G117100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVE3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="9128" checksum="12F996FE8BBBA230" modified="2022-10-12" version="1" fragment="single">IRNQGPHQRLYLLHPQQGFLTKNKLFKDGVGAQCFTNPAYTFSVGGIICSIYPQLLEFLVETKCVCQLYNFIIVYSRHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXM9</accession>
    <name>A0A8T0IXM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G203800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032588">
        <property type="term" value="C:trans-Golgi network membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035091">
        <property type="term" value="F:phosphatidylinositol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03572">
        <property type="entry name" value="ENTH_like_Tepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035802">
        <property type="entry name" value="ENTH/VHS_tepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008942">
        <property type="entry name" value="ENTH_VHS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039273">
        <property type="entry name" value="TEPSIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002014">
        <property type="entry name" value="VHS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21514:SF0">
        <property type="entry name" value="AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00288">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50179">
        <property type="entry name" value="VHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VHS" evidence="6">
        <location>
            <begin position="35"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="139"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="370"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="708"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="216"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="416"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="717"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0587947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="733" mass="77204" checksum="5EB42571E944FD38" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J010</accession>
    <name>A0A8T0J010_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_2G234000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J010"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000097">
        <property type="entry name" value="Cytochrome P-450 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF4">
        <property type="entry name" value="OS09G0441700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="8 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0588318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="518" mass="58915" checksum="819D0C1E86122C00" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J047</accession>
    <name>A0A8T0J047_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G254700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J047"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015630">
        <property type="term" value="C:microtubule cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF23">
        <property type="entry name" value="KINESIN MOTOR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="4">
        <location>
            <begin position="151"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="552"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="674"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="562"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="228"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0588592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="765" mass="84435" checksum="284213DA9F192AC0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0B5</accession>
    <name>A0A8T0J0B5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL5c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L5, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G287600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0B5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1440.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_uL5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_uL5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_uL5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_uL5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020929">
        <property type="entry name" value="Ribosomal_uL5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_uL5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_uL5_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000585">
        <property type="entry name" value="PRK00010.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="RL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00358">
        <property type="entry name" value="RIBOSOMAL_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035775257" description="Large ribosomal subunit protein uL5c" evidence="7">
        <location>
            <begin position="22"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 N-terminal" evidence="8">
        <location>
            <begin position="93"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL5 C-terminal" evidence="9">
        <location>
            <begin position="153"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0589045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="272" mass="29178" checksum="5D4185EE6FF14259" modified="2022-10-12" version="1">MAAMACTAAAATASLVASTSACTSSTSSALMGSRVAVAPVGARRLACRGAVAVSASAAVAVEDQTEERTVQRLLGIYQEKVVPAMQEEFKYGNKFEIPHVKKIIVNCGVGEASQNAKALEGTIRDIALVTGQKSVVTRSRKAIAGFKLREGVPVGVTLTLRGDMMYSFLDRLLNLALPRTRDFQGVNPYSFDGRGNYTLGLPEISVFPEIKFENIDKQRGMDICIVTTAKNDSEGLKLLELMGMPFKEMGGGRMSASAAKKATRTTFRGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0G2</accession>
    <name>A0A8T0J0G2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G291000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0G2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035856073" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="6942" checksum="DEF60D73E08BD778" modified="2022-10-12" version="1">MLVLEAIAIAIAIATVKALGEIPISIPSSSPILGRSVAWPAMAPESIAPSVLCVCVCVCSLPPSVTPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0L4</accession>
    <name>A0A8T0J0L4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G243100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0L4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032454">
        <property type="term" value="F:histone H3K9 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045109">
        <property type="entry name" value="LSDs-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014977">
        <property type="entry name" value="WRC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018866">
        <property type="entry name" value="Znf-4CXXC_R1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549:SF38">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLASE 2, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12549">
        <property type="entry name" value="JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08879">
        <property type="entry name" value="WRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10497">
        <property type="entry name" value="zf-4CXXC_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51667">
        <property type="entry name" value="WRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WRC" evidence="11">
        <location>
            <begin position="19"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="250"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="JmjC" evidence="10">
        <location>
            <begin position="867"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="422"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="524"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="142"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="186"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="431"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="461"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="533"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="566"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0588441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1223" mass="137297" checksum="2EB8AB6A97243A3B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1Z4</accession>
    <name>A0A8T0J1Z4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G277000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1Z4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8644" checksum="6B43000E320875D9" modified="2022-10-12" version="1" fragment="single">ILIAAHNYFSILANASFSWQQEFGGTAWGGLDLKQRNSLALLSRKKALILVHVDTVAVHQILQKKKLVIMKGLNWTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2A8</accession>
    <name>A0A8T0J2A8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase C14 caspase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G066400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C14B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050452">
        <property type="entry name" value="Metacaspase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011600">
        <property type="entry name" value="Pept_C14_caspase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104:SF30">
        <property type="entry name" value="METACASPASE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48104">
        <property type="entry name" value="METACASPASE-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00656">
        <property type="entry name" value="Peptidase_C14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="Caspase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase C14 caspase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35821" checksum="49640CED451E3437" modified="2022-10-12" version="1">MGTKKALLVGINYRGASGINELNGCCNDARRLSNVLMNFYGFEGTDIDILVDEPADGERDLPTHANIHKYLKKLIDGAQSGDTLVFSFSGHGGRVKIGSLGEDHSQDTDYDNTGYNEMICPYDHTNVLTDDDLREIVSGIPAGVNFTVISDSCNSGGLIDEMVEQVGGAELKYEEELRVSEGSGGSKRLTEDMLISSLNNDDRISDPVDDSNIGRVLYDLYKDDSSLTFKCRFNQDAYSRAGSKSDDVGILLSACESWEFSTDTADGGVFTVALESVLEELRSAGESSPTYRQLIMAVRGKIEEVSESQHPCLYCSDTNADALFVGEFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2W3</accession>
    <name>A0A8T0J2W3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G054700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2W3"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46863">
        <property type="entry name" value="OS09G0572100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46863:SF1">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="96"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="48566" checksum="AF4B26133AB3D413" modified="2022-10-12" version="1">MCLFRLRWPKQAQSRASSQVGTPKPRPFRKSPEDTSLELSTSYTISQSLSKESKGESRGSQTSTGSAISLASLKGMLSDGAQIFTHRDIIKATDNFSLGRKLGAGTFRGTMGGKNVTVVVEKRVSMDVDFVAEVKSICNLHHSSLARLIGACISGDQLYLVYEYIAGANLRHCLRSVIAPGFTTLKSWTVRLRVALDIAKGLEYLHEHASPPFVHKYIKSTSIILDNELHPRIANVGVARIRGETAVDPGASLYSASGKEVKTLDPNSSSRHQQQQQGVHLGRALGRSLGRSRSVKITGTHGYMAPEYTLSGLITPKLDVYAFGVVFLEILSGQEAVKLQQNPGEMEMRKTVLPDVIAAIFSDPEPRPKVRAWIDPLLRDAFPLDCACRAALVARKCVEANPDDRPPMRNVALSLEQIYMASKQWEDSMLASNDLMTNTLTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J387</accession>
    <name>A0A8T0J387_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-carotene isomerase D27-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G063300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J387"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038938">
        <property type="entry name" value="D27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025114">
        <property type="entry name" value="D27-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591">
        <property type="entry name" value="BETA-CAROTENE ISOMERASE D27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591:SF4">
        <property type="entry name" value="OS08G0114100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13225">
        <property type="entry name" value="D27-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-carotene isomerase D27-like C-terminal" evidence="1">
        <location>
            <begin position="149"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="273" mass="30092" checksum="7DFB160BFD9AFF12" modified="2022-10-12" version="1">MHSVAVRTPWEGACTSLRSSRNHESRVATNSRPCVVRCGVAEPDGKPVPFGQLTRYNDNLLDKAFMALFRRKMEQFTGKSTPLQGYEGFVDVSKKIMQGRTAVEQRAVVRNVLLSLLPPGAPAQFRKLFPPTKWSAEVNAAITVPFFQWLVGPAELMEIEVNGVKQMSGVKITKCRYLENSGCVGMCVNMCKIPTQDFFTNEFGLPLTMTPNFEDMSCEMFYGQAPPPIAEDPAIQQPCFASMCSIAPPKSTACPKLQVAQDLSPSEVSLSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4V3</accession>
    <name>A0A8T0J4V3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G085500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7954" checksum="981290DEDF4F65F6" modified="2022-10-12" version="1">MSTSAHIGTDVGTWNTVNIGMSSEPGLCNLASHLTLKNKHDKGSRKIWYKDKTRRFWIQKEHVKTQRDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5Q7</accession>
    <name>A0A8T0J5Q7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G093300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5Q7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035859857" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="7161" checksum="5C83FD1C46D75361" modified="2022-10-12" version="1">MWAVLVLFVVVGRPLGLCFRLARSIEPPLVVGIFCRFEFNCRMFVHFVVDTVVMDRSNEGASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J806</accession>
    <name>A0A8T0J806_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G191100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J806"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31718:SF60">
        <property type="entry name" value="LIPOXYGENASE HOMOLOGY DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31718">
        <property type="entry name" value="PLAT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01477">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035931230" description="PLAT domain-containing protein" evidence="3">
        <location>
            <begin position="32"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="PLAT" evidence="4">
        <location>
            <begin position="260"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="172"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="40355" checksum="5C319837ED7B3550" modified="2022-10-12" version="1">MRTTSNGSFQGEGKLLVAVLVLAVMCSPVMGSRFMKPTTSAHVDHSREPSPPPPPALRWWQHPPPPPLIIQWPPPIRHYPRHYPPSPPPPPRSPPPPRSPPPPSPPLSPPPSPPPPPLSSPPPPPPSPPPPPSLSPPSSPAPPPDQVKPSLKHSENGRRLLSSEAGPDSEQNHFLVTDSSPGKCTTYPAMSPSTSPDAPPLDPYGGYIAPVGAPYPSSDPGALSPVPAPAPMSGADSPESGDNGPMAHTTMVSAMKYNQCTYTIITSTGNIEGAGTQADVNVEFFDKYGDSVLFVNLRSQNRNFDRGSTDTFTVVGDCVPNICRMHLSHDDSGPNPGWFVNTVTVSLQYQTHVFNVFEWLSKTEPPYSLSRTISSCPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9Y8</accession>
    <name>A0A8T0J9Y8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G276400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9Y8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10166" checksum="DAB4D78E954DC7F8" modified="2022-10-12" version="1">MPSSSGANSQRCQEGVTEFSGRPSDRFGITSAVTQLLGIRCRAWRAPYACFLRRRGLTARKTGIGKLAVYAGTLFQGSLWFRSCFTFCLLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAC1</accession>
    <name>A0A8T0JAC1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G273800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAC1"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7992" checksum="A47DCD0BDDA2612D" modified="2022-10-12" version="1">MMSGVVTTRFWRAPKILPLKVREGIAEAKKFMTHAIDVYSFAMTSYEVITGLIDLEGHRLFMSMVVEGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBT8</accession>
    <name>A0A8T0JBT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G258500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBT8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35737">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35737:SF1">
        <property type="entry name" value="CRYPTIC LOCI REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="189" mass="20868" checksum="4148DFC247E36689" modified="2022-10-12" version="1">MAASEFETVEDGGFVFKVRKKRLEEIQAAPVAVEGGAVREAPVPVAEESFEVEKKKKKLLTLKAMYEAELKAWEKLEAAATAPVLEELPSNSENSVPEEDPQTDMLKELKIEVENVEEYIKRLQDHIIHAKSTYKVMMKELREDADFRPAAEIVLALTGQGDTTSDNDVIATQGSLGSSGSLNKFADID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCK8</accession>
    <name>A0A8T0JCK8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G251700</name>
        <name evidence="3" type="ORF">KC19_1G252000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCK8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274587" evidence="1">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6310" checksum="58D3193853C7C8FD" modified="2022-10-12" version="1">MNMHLFWLLFTTVLRDCRSPGLFFLNTAFKFILCMVEAGAGANDSQLQVHFLMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4B7</accession>
    <name>A0A8T0G4B7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G048100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4B7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="8214" checksum="3071291E6EA92C90" modified="2022-10-12" version="1">MERMHVTVKFQTIVHMLVHQLFMSSSVVHQFMLDRQVSNDCSYDSKHKHMAAALLSTETLEMNQYMVCHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G753</accession>
    <name>A0A8T0G753_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G077100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G753"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12854">
        <property type="entry name" value="PPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="261"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="366"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="401"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="436"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="506"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="541"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="576"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="611"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="646"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="115"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="140"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0554254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="744" mass="82647" checksum="D0B11CF633D32DDC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9Y4</accession>
    <name>A0A8T0G9Y4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G061800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9Y4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="13280" checksum="4CEE36F089912656" modified="2022-10-12" version="1">MWQITNPRLGWRARRFGVHLTCLRSGSVELPFSRALDVSSYSMTLYEVRTGHIPFEYGCGHSSDSVSASQLTTQCPCPATCCTMCQTRLLATGYWQRKSVPHGSKPEVTAWTFLGDTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2023-09-13" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAZ5</accession>
    <name>A0A8T0GAZ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-terminal of Roc (COR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G045000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF1">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035936671" description="C-terminal of Roc (COR) domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="1361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1361" mass="154420" checksum="022797B4FDA0FD92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCN9</accession>
    <name>A0A8T0GCN9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G003900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46020:SF4">
        <property type="entry name" value="OS04G0650200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46020">
        <property type="entry name" value="OSJNBB0059K02.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52266">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0555799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="332" mass="37182" checksum="7DAFAA60A2B7EAD5" modified="2022-10-12" version="1">MIFCLAAESTSNNVKAIYAFGDSYVDTGNVNHENGSLTWDKPYGITWPGYADGRFSDGQIETDYIAHYFNLPSPVPFNQILNYNTYNGINFAVGSSGVTYANKKPTLNVQVNQFEECLENGIIKKQDLQNSIAFIGTGVNDYTSYKGLNETIPALLDNVVDGLAWNVLRLFKMGIHNILVSNLAPMSCFPQYTAIYNYTHCLDNTTLTYKTQELHNIKLENAMTSLDKNVEGLKILLLDQSKAFQYLVDSASILGFEDSVIPCCKGAMDNDVLKCGKDDQYGHPLYSLCKDPTKALFWDGWHLTETAYEAIIQLYTFKTGFTKLADNLKSWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE88</accession>
    <name>A0A8T0GE88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fibronectin type-III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G029800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050617">
        <property type="entry name" value="E3_ligase_FN3/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24099:SF11">
        <property type="entry name" value="FIBRONECTIN TYPE III DOMAIN-CONTAINING 3BA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00014">
        <property type="entry name" value="FNTYPEIII"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="Fibronectin type III"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="260"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="374"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="481"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="576"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="671"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="886"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="985"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="1112"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="572"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="891"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1282" mass="136460" checksum="FA3EB0C367968EFF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEP4</accession>
    <name>A0A8T0GEP4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine synthase</fullName>
            <ecNumber evidence="9">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G079400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="9"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000006">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000130">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="10">
        <location>
            <begin position="87"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0556794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="400" mass="41744" checksum="2DB0258D7A99606A" modified="2022-10-12" version="1">MAALRQASNVAVGCMAPAAAAQGVRDAGASRRVKVSSLDSAMAGVHLKAVRAGANAVDSSRRMRGVVSQAVSVGTEKELEMNIADDVTQLIGKTPMVYLNTVVEGCVANIAAKLEIMEPCCSVKDRIGFSMISDAESKGAITPGKSILVEPTSGNTGIGLAFIAAAKGYKLVLTMPASMSMERRILLRAFGAELVLTDPAKGMKGAVQKAEEIVKKTPNSYMLQQFENPANPKVHFETTGPEIWEDTAGKIDILVSGIGTGGTVTGTGRYLKSKNPDVKIIGVEPTESSVLSGGKPGPHKIQGIGAGFIPGILDVEILDEIIQITSNDAVEMAKQLALKEGLLVGISSGAATAAAIQVAKRPENKGKLIAVILPSFGERYLSSVLFQSIRDEAEAMTPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF27</accession>
    <name>A0A8T0GF27_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G145600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10036" checksum="6E97FD0FD1B6E05D" modified="2022-10-12" version="1">MSYQFGFLSLPANDADTLDVPVSSKRDKHPAERGASGGEDDKLPGGYRQKLLHEIVRRPGVDDELGGCSSVMASSTGHTSFASTYTLAMSQSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH08</accession>
    <name>A0A8T0GH08_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G131200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DVL/RTFL small polypeptides family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH08"/>
    <dbReference type="OrthoDB" id="602011at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008285">
        <property type="term" value="P:negative regulation of cell population proliferation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048367">
        <property type="term" value="P:shoot system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012552">
        <property type="entry name" value="DVL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08137">
        <property type="entry name" value="DVL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="7852" checksum="1E06B3A0E55209BC" modified="2022-10-12" version="1">MCFGRDGAGGDESDSWKSGGGKRGSEDGGFYSLHHNNCLSNAAKNTISFVKHQRGKLYIVRRCVTMLLWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHX9</accession>
    <name>A0A8T0GHX9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G077000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035841396" evidence="2">
        <location>
            <begin position="27"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="41501" checksum="7A815F92E1283192" modified="2022-10-12" version="1">MRQSTSSMKLAWLSLGLAIQLHFVVGSGPESLPGLPVYAFSMSNCSQFRNEMVLRPKFGVWPEDIKGVPFQYCCEYQPNGALSTFELSKYAYGSEGGVLQPAPYFDLGIVDNERLQYYWKNWRYNSLPEKQVSSVRTLYCDVTDLRRLYNYRFWNKSIVKGATAWAVVIAPLVLLVSILVLLGSKFNMGTYKTRKDTKRRSLDKEEAFADACHILLLALVGSSLMEGIAHAPLRTWRSQLMYKGGVTYVYLTLGALISTFIRHCVALDLRIWRLGKGQEASWLWQKVFLQFVALFMVGTYLELVEDVTEHSLDAVSSLALGTCTAASVWSAGVELVVLVRFSYLKIIRHNLRMDRSNSAVHAHSDFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI65</accession>
    <name>A0A8T0GI65_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G083300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="80"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1320" mass="149472" checksum="3361331F587130D2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ23</accession>
    <name>A0A8T0GJ23_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box associated beta-propeller type 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G106800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ23"/>
    <dbReference type="OrthoDB" id="1913441at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017451">
        <property type="entry name" value="F-box-assoc_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01640">
        <property type="entry name" value="F_box_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box associated beta-propeller type 1" evidence="1">
        <location>
            <begin position="176"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="49464" checksum="DD736F043033A260" modified="2022-10-12" version="1">MIQVIIRQTSGVTLGMNLIEASPMGHDDSKEAERTVLSQDGSISERAMLGLPPDLEDLVLARAPISVLYKARPVCKRWYSLLTHPPFLSLRSEILGPQEASFFPIVFWNDGKATLRISRTGSKLESIADLEPIYPTAPDPATVDPGHAENERATWSWLGYDSSRRRWQTLKPFTTPIDVKNVITGSKGLLCLRSESSFLVLNPMTGAQREVPLKENVVQFVVDTEQKSFKIICAASRKRTKIYDSKTGLWSKRGRPTPNLALEKHIGAYHDGVLYCVAREERSGRWGVVQYHVEGARTWSNVVFFPQRAGESVLKAKVFQFGGEIFALIENEISEDDIGPRTKSLTLWKLETASLQWRLAGLMPTASREYLVNLDDLDCVPLNNRLCILNKSTFKAVACFISGGVVTAWQEFPLHSYFSADTLLVERCIVQFAFEPSLLVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ36</accession>
    <name>A0A8T0GJ36_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G072300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ36"/>
    <dbReference type="OrthoDB" id="359154at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_uL24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_uL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057264">
        <property type="entry name" value="Ribosomal_uL24_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0559023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="181" mass="20089" checksum="5FC28D254360F313" modified="2022-10-12" version="1">MAMAVQSPLHIDSLSNGFLGMGLNTGRPTSQASPKVNTSIRMAIKRWERKEVKENSLPVVKKLHVKIGDTVKVIAGHDKGKISTVTQLYTHNSKIMLKDVNLKTKHVKGKAEGETGQIVQVEAPIHSSNVMLYSKTAKVASRVGHKTLEDGSRVRYLLKTGEVIDSAEEWKKVHKKEEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJE5</accession>
    <name>A0A8T0GJE5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoenolpyruvate carboxylase</fullName>
            <ecNumber evidence="5">4.1.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_10G117500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>oxaloacetate + phosphate = phosphoenolpyruvate + hydrogencarbonate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PEPCase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.31" evidence="5"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJE5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1440.90:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.90">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00595">
        <property type="entry name" value="PEPcase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022805">
        <property type="entry name" value="PEP_COase_bac/pln-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018129">
        <property type="entry name" value="PEP_COase_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523:SF6">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00781">
        <property type="entry name" value="PEPCASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="395"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0559601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1081" mass="121197" checksum="469D71C8B72A0F6C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK25</accession>
    <name>A0A8T0GK25_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G133100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18918">
        <property type="entry name" value="bHLH_AtMYC1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045895">
        <property type="entry name" value="bHLH91-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045896">
        <property type="entry name" value="MYC1-like_bHLH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46834:SF1">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46834">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="5">
        <location>
            <begin position="408"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="380"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="475"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="499"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="622" mass="67851" checksum="0FF2756A7AED832B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKN8</accession>
    <name>A0A8T0GKN8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G055300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016926">
        <property type="term" value="P:protein desumoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46915">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="domain" description="Myb-like" evidence="6">
        <location>
            <begin position="67"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="7">
        <location>
            <begin position="404"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="636" mass="72099" checksum="EFE2C611D6E5E3EA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMS1</accession>
    <name>A0A8T0GMS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G131300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMS1"/>
    <dbReference type="OrthoDB" id="1864231at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873:SF3">
        <property type="entry name" value="PPIASE CYCLOPHILIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="75"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="235" mass="26542" checksum="5C9F43BA4E115312" modified="2022-10-12" version="1">MECGRRLTSCFEHHKILDILMLSLVVIVTMLANFASGLSRDSAFLGYSERPLVIPQYHGYPLRPKERLVFATKYGDITVELKREMAFKTVQYVKSLVSRGLFNGCGFYRAEPPGPTMDDGRNDTRKGYALLQGGLYSCGRQENKDLPLETKLDNSKGTVALITGTSEFFFSLEDHHEWNGSFSVFGTVVGEPSWRALERLVALPTRQELHPSGTVMRILLKPVIFKVSVEQHFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMX5</accession>
    <name>A0A8T0GMX5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL29c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">50S ribosomal protein L29, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G140000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00427">
        <property type="entry name" value="Ribosomal_L29_HIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_uL29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050063">
        <property type="entry name" value="Ribosomal_protein_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_uL29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_uL29_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_uL29_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10916">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L35/50S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10916:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL29C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="Ribosomal protein L29 (L29p)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="18934" checksum="57194A663608B048" modified="2022-10-12" version="1">MATMADVSRAAVLCASVPSVSGSVVAKPRVSVAASPFFNQGVKSLSATVSSVRSSVVNGSPLVVNMAKREEELVGIRKMSDEDINQTVVDLKGELFILRSKQATRQEFKSSEFRRIRKNIARMMTVKREREIERGVGIRESRKLDREWKRNIVIRPPPSYAASLAEQEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNN0</accession>
    <name>A0A8T0GNN0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G133900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621">
        <property type="entry name" value="ASPARTIC/GLUTAMIC ACID-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621:SF2">
        <property type="entry name" value="RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="359" mass="39042" checksum="5E67989BB8A99F30" modified="2022-10-12" version="1">MSYHELTRKELQALCKQNGLPANKSNVVMASSLESFFSEQQTLTQAYAQFGTPCTVTKSVKARAVPKLERLETSLASLILGSVQPSAKGGQDSLLKKCKEPGAISAFLVSSPADNGDSILLPKTTPLRRRRKKSDAVKALPICAEDAISRDVAQVPADSTENLRLLPEETSVHTNTSQIVVKKISTPEPQLAPHFNADVLVTDTQGSPRTRGLEHQEDVASTTGVELVVKREVLSPSGSEPVASSSAHDQDYQNMFNAGCSQPVLMSPLLRITANVDTLILRATGMLEKFEQWKTGSPNKDFVHCSGQKHLSFDKENLHQQSPCKNSKLRSLQGCMGTNAAQQDRKENILKDIVPNAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNQ4</accession>
    <name>A0A8T0GNQ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G099400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNQ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11949" checksum="7440AABD0D3BFFDD" modified="2022-10-12" version="1">MCIIRLSFLHVRQNLFPRLCRHLESRIPLVTLVLQQLYLRLHHEVGVVPSLRLVFEELIPVRTCITPHAWNLPVVSTAYEHSVFGPCTTPPICKRGIVVVHGPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVB6</accession>
    <name>A0A8T0GVB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G051800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12413">
        <property type="entry name" value="RRM1_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12415">
        <property type="entry name" value="RRM3_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="298"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="570"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="724"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="384"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="523"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="837"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="393"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="525"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="849"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="886"/>
            <end position="896"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="896" mass="98336" checksum="59EAC90B3EBA5A1C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXY8</accession>
    <name>A0A8T0GXY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G067500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="3">
        <location>
            <begin position="50"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="254" mass="27727" checksum="A8AF8E459B28E39B" modified="2022-10-12" version="1">MEGAEKSAGAVAERHKDEVDMTMNASAFSIYQNLESLPNKNLCVQGLNVLVSIISVLPRLDTNIKAPQVLIVCASKEDAAHIQKVITHCTEGQGKITARLATPSAPERPSKRAMVEDQVVVGTSGTMKSYITSKWLNTTSMKIVLVDEADGMFDQHETGRLHDTKKMLKIINPSGGNCQVILLSETSSERVKRSAMKEFREVGSWSSVVLEKPSHDLNCQYQIAQSCPETLSKISALKKDVDAAGMCKGGWVQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY13</accession>
    <name>A0A8T0GY13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_8G122200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SINA (Seven in absentia) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16571">
        <property type="entry name" value="RING-HC_SIAHs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052088">
        <property type="entry name" value="E3_ubiquitin-ligase_SINA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049548">
        <property type="entry name" value="Sina-like_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315">
        <property type="entry name" value="E3 UBIQUITIN PROTEIN LIGASE SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10315:SF83">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21362">
        <property type="entry name" value="Sina_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21361">
        <property type="entry name" value="Sina_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="44"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="SIAH-type" evidence="13">
        <location>
            <begin position="98"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="296"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0564576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="37645" checksum="96D76124B89B69AE" modified="2022-10-12" version="1">MTSSTGAHTGQEAGSSSHKRKRAGSDVEEVVDRKYGLDIDILDCPICLEPFVRPVYQCKNGHTICLSCCKKLAPKRCPTCSAVTGKIRCIAIEKILESLLVSCKNAEHGCKKMLNRTDMIEHENHDCLYEPFPCPVENCVCTFCSDVGFIAHMTEVHQVPTVHGTGYEVIGIRMISWNQFVLVDVKGGGKNEKSHLFFLVHRQVHSDLGDIFFCSSFQGRSNKRNRYKLQAEVSFDRSVYSIDRAVALDLRHRGFTNYRKQHFLLVPFRQPRPTYDNYRLAEVEFSVCQNDEDECLLPDTEDDEVEDNDTQNDDSEDADPEDDNYELAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY26</accession>
    <name>A0A8T0GY26_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U3 small nucleolar RNA-associated protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G023100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY26"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006709">
        <property type="entry name" value="SSU_processome_Utp14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14150:SF12">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 HOMOLOG A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04615">
        <property type="entry name" value="Utp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="498"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="582"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="788"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="861"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="969"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="148"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="237"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="500"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="586"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="643"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="670"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="688"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="724"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="791"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="877"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="972"/>
            <end position="989"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0563345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1002" mass="111048" checksum="237E4F8AF5166EF9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0W3</accession>
    <name>A0A8T0H0W3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G152600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0W3"/>
    <dbReference type="OrthoDB" id="551907at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000002">
        <property type="entry name" value="Myb family transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025756">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499:SF43">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR APL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14379">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="47"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="111"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="250"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="298"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0564960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="494" mass="53005" checksum="A3F1C7FBEA01DE6B" modified="2022-10-12" version="1">MFQMKKYMSPGTFQQRPQPGSVYMPDKLQSPYASAMNGGDMVPLSPADPKPRLRWTPELHERFVDAVTQLGGADKATPKSVMRIMGVKGLTLYHLKSHLQKYRLGKQLNRDSHLHGSNKDGGSPDGQRSNSLSDGVSTQKSQNPQDGLQMTEAIQLQLEVQQRLQDQLEVQRHLQMRIEAQGKYLQSILEKAKETLAGHTSDSPGLEAAHAELTELASKVTTVGMIPSGFSNLGMPPMTQPDPLMALHQLPRQPSRNSDSSSQKSFLTNLTGNAEDSGGVSGSGDPHGAAEDEDGVGQESSTVQFQEEMSANRLRPQGSGNARGSQARLAAHAAAASGALPPGVTLSSVASPHHSASFWPPSGSSFQTMNTVLSDHQVDQLGGHNDNNASHLATSMALERQLQQQPAWTMGGGQLGSLQGVPNAGSFTSLQELYGQELGRSGAVGMHGSSAHVKAEIGHMDQQNHGHGNINSFIQCREGQQVDRSELSFTYSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2C1</accession>
    <name>A0A8T0H2C1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mitochondrial import inner membrane translocase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G181800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small Tim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2C1"/>
    <dbReference type="OrthoDB" id="344165at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.810">
        <property type="entry name" value="Mitochondrial import inner membrane translocase subunit tim13 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004217">
        <property type="entry name" value="Tim10-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035427">
        <property type="entry name" value="Tim10-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02953">
        <property type="entry name" value="zf-Tim10_DDP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144122">
        <property type="entry name" value="Tim10-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="1" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0811">Translocation</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Tim10-like" evidence="2">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8517" checksum="AEB50FAFA92587A5" modified="2022-10-12" version="1">MDSGNSFQMQQFLQQEKQKAALNELVGKLTDACWDKCITSTPGSKFSSSESSCLTNCAQRFLETSTLILRRFQSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H452</accession>
    <name>A0A8T0H452_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G148900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H452"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="12212" checksum="C282B60440FB2325" modified="2022-10-12" version="1">MSGVQTMPPESSEECGKELVIINGNSPLIHTTTSAHPPPDPSLPKGLLSGSLVNAHTCILSHPITKSCIPSPSVTALQFIPVVGLVGDNQEKKKKKKKTVVGLHQVVISITLVEGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H498</accession>
    <name>A0A8T0H498_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TNFR-Cys domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G070600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H498"/>
    <dbReference type="OrthoDB" id="2013942at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035795470" description="TNFR-Cys domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="534"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="534" mass="57971" checksum="B56E8A781AD4DEF0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H528</accession>
    <name>A0A8T0H528_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G195600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H528"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14340" checksum="94C2AC89E39D1A36" modified="2022-10-12" version="1">MGVDRPRRGYASSSKPRMAATTDQGEAKVGTVAVTSNFQEANPKGSDDIWEQVPEEERARFQKEKEFRRNLHRRCLQKAAADVESRKRLLQRGELDNLQSSVRPVIWGSALYRGLWAKAAKIKEPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5J2</accession>
    <name>A0A8T0H5J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Casein kinase substrate phosphoprotein PP28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G004600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5J2"/>
    <dbReference type="OrthoDB" id="21120at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019380">
        <property type="entry name" value="Casein_kinase_sb_PP28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039876">
        <property type="entry name" value="HAP28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22055">
        <property type="entry name" value="28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10252">
        <property type="entry name" value="PP28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Casein kinase substrate phosphoprotein PP28" evidence="2">
        <location>
            <begin position="76"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="18821" checksum="6BD4DAABA6DE1C5E" modified="2022-10-12" version="1">MGGGAGRGKFKGKPTGRRHFSTPEEMAAGTSTKPRSFKRNPEEEEEESEEEESEEESEEEESSKKKGTQGVIQIENPNLVKAKNVKAKDVDMDRPAELSRREREELEKQKAHERYLKLQEQGKTEQSKKDLERLALIRQQRLEAAKKREEEKAAKDAKKVEARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N6</accession>
    <name>A0A8T0H5N6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G001100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046964">
        <property type="term" value="F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF13">
        <property type="entry name" value="ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0565609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="381" mass="42558" checksum="AE2C4531678780D1" modified="2022-10-12" version="1">MASGFNLIMELFASTTLWFHKEPVKLALASLAIAFLKVSITTFTPILAAFQSYGEKHVNFTAFGAFSKLCGSLATCATAGALLLARGKKHFTVRAPLYAYAVIATAAAVAIGVENQLNHGVGEEWNLSWQCLIIFIVMALQMLMLRREFSRWDWIASGLFVCSCVVSALPWLSMKEANNTNPWYLALGGISVAFAYLVMEGINQTYQDKLFCDIDTTITEQVFFISVFATLIRIIGFLWEFRCLEAIMFHTRHPLSFTSVLLLSFMGAAMTFLMSYMLQLCGALICVMIHQIMVNILAGKSQELNLADIALKWVGIIFMLGMLGRTMSKMQHNHHKVGKLELTDEELEELGVSESDNERDNERLLFGVQSVDNLVQLRETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8I5</accession>
    <name>A0A8T0H8I5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RSE1/DDB1/CPSF1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G155900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DDB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8I5"/>
    <dbReference type="OrthoDB" id="433457at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.910:FF:000003">
        <property type="entry name" value="DNA damage-binding protein 1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="4">
        <location>
            <begin position="6"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0567723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13066" checksum="4576977DFAEC900A" modified="2022-10-12" version="1">MRLPDSEASQIPTVIFGTVNGVIGVIASLPQEQFLFLQKLQQALVKVIKGVGGLSHEQWRSFSNERKTVDARNFLDGDLIESFLDLSRNKMEEIASPLDISVEELCKRVEELTRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9M1</accession>
    <name>A0A8T0H9M1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G028000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">ATP-dependent specificity component of the mitochondrial Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9M1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19497">
        <property type="entry name" value="RecA-like_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000002">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000560">
        <property type="entry name" value="CLP protease regulatory subunit CLPX3 mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050052">
        <property type="entry name" value="ATP-dep_Clp_protease_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003745">
        <property type="entry name" value="PRK05342.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102:SF7">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48102">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="306"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Clp ATPase C-terminal" evidence="11">
        <location>
            <begin position="517"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="169"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="631"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="188"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="646"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00055633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0568551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="664" mass="71143" checksum="85FD2BBC3B9C99D3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA35</accession>
    <name>A0A8T0HA35_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G119100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056813">
        <property type="entry name" value="GIL1_IRKI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989">
        <property type="entry name" value="OS01G0750732 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989:SF62">
        <property type="entry name" value="OS05G0423500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24994">
        <property type="entry name" value="GIL1_IRKI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="541"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="385"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="481"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="439"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="489"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="569"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0567214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="875" mass="97117" checksum="0691957DC9CAA71F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDF8</accession>
    <name>A0A8T0HDF8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G039000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="6967" checksum="EB15F6C033A5CD62" modified="2022-10-12" version="1">MDGDSFPSVSAFGWHGLISFADLEGFVETRLPRLLQRFEVAPSSGIWRARQTSPLSIGFRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEK6</accession>
    <name>A0A8T0HEK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_6G111200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 16">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEK6"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000004">
        <property type="entry name" value="Probable protein phosphatase 2C 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13832:SF790">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="13">
        <location>
            <begin position="109"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="68"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0569720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="413" mass="44343" checksum="3EA6415A02DC7F51" modified="2022-10-12" version="1">MAVGTEVAHPVNILDGVSKVPVAVSSKERGAAGDNTVEVAAETEANMVAAITTSCNVTEAGLGGSLSSISEGCTDETQPVTSPSTSVEKVDEKNDEEPVNVPDYVPEYRSGGCAERGIRRSMEDAHLCVDDLEESLGSPGAFYGVFDGHDGEAAAGYVKEHLLPYILGDASFPTAVEEAVKNAYLELDKKFSEACRLDDSLSSGTTVLTALVQGRNLLVANAGDCRAVLCRKGVAVPMSRDHDPSSAWEKSRIESVGGYVVDGYVNGQVTVARAIGDWHMQGLKEEGGQGPLSAMPEIQSMVLSEEDEFLLMGCDGLWDVFTNEGAISFARKQLQRHNDPEQCSRELVVEALRRNSQDNVTVIVICFRADAPPPLVVLERRTTIRNFCLKKMLSVQKDIDIAQASASERRCVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF51</accession>
    <name>A0A8T0HF51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G049600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050500">
        <property type="entry name" value="Phos_Acetyltrans/Butyryltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004167">
        <property type="entry name" value="PRK05632.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007233">
        <property type="entry name" value="PRK09653.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43356:SF3">
        <property type="entry name" value="PHOSPHATE ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13500">
        <property type="entry name" value="AAA_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="HprK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="8">
        <location>
            <begin position="276"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphate acetyl/butaryl transferase" evidence="7">
        <location>
            <begin position="445"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0568854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="788" mass="85491" checksum="AC16491FD8AFE198" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGH9</accession>
    <name>A0A8T0HGH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G161700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="15554" checksum="293B2B409A8B807B" modified="2022-10-12" version="1">MAKVPHEAPTSISQIITHTYILTLQQKHNNATTLKSSKSFLPQLNHESDMQAGSARSSTELFSRLSHVTNVYTNAATSEILKTTEILHPSTASSVPKSGQYSVMICSMSVSLQALSNESLGHARSLPKDNAWSNSSASTLICVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHE3</accession>
    <name>A0A8T0HHE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha,alpha-trehalose-phosphate synthase (UDP-forming)</fullName>
            <ecNumber evidence="3">2.4.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G144100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHE3"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000010">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1020:FF:000001">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000046">
        <property type="entry name" value="alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011071">
        <property type="entry name" value="PRK14501.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF106">
        <property type="entry name" value="BCDNA.GH08860"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0570207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="919" mass="103324" checksum="12EFA1B260511A15" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHP2</accession>
    <name>A0A8T0HHP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial Rho GTPase</fullName>
            <ecNumber evidence="14">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_6G117800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion outer membrane</location>
            <topology evidence="1 14">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the mitochondrial Rho GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="14"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000011">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000553">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000935">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013566">
        <property type="entry name" value="EF_hand_assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013567">
        <property type="entry name" value="EF_hand_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021181">
        <property type="entry name" value="Miro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052266">
        <property type="entry name" value="Miro-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020860">
        <property type="entry name" value="MIRO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08355">
        <property type="entry name" value="EF_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08356">
        <property type="entry name" value="EF_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037488">
        <property type="entry name" value="Mt_Rho_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51423">
        <property type="entry name" value="MIRO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 14" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="615"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="16">
        <location>
            <begin position="10"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="16">
        <location>
            <begin position="421"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR037488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0569809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="644" mass="72313" checksum="CCEA1E709488F005" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK14</accession>
    <name>A0A8T0HK14_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phenylalanine ammonia-lyase</fullName>
            <ecNumber evidence="8">4.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G213600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-phenylalanine = (E)-cinnamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21384"/>
            <dbReference type="ChEBI" id="CHEBI:15669"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="EC" id="4.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.24" evidence="8"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK14"/>
    <dbReference type="OrthoDB" id="10051290at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045548">
        <property type="term" value="F:phenylalanine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009698">
        <property type="term" value="P:phenylpropanoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000009">
        <property type="entry name" value="Phenylalanine ammonia-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0587">Phenylpropanoid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0571137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="742" mass="80984" checksum="6278B35250872E9B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNR3</accession>
    <name>A0A8T0HNR3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_VG095100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 14">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009738">
        <property type="term" value="P:abscisic acid-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14665">
        <property type="entry name" value="STKc_SnRK2-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000085">
        <property type="entry name" value="Serine/threonine-protein kinase SRK2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000045">
        <property type="entry name" value="Serine/threonine-protein kinase SRK2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343">
        <property type="entry name" value="SERINE/THREONINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24343:SF509">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE SRK2E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="15"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0572439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="39693" checksum="C1D7282C9B686FB7" modified="2022-10-12" version="1">MDHVDIPSMHDHDRYELVKDIGSGNFGVARLMRDKLTRECVAVKYIERGEKIDENVQREIINHRSLRHPNIVRFKEVMLTPSHLAIVMEYAAGGELFERICNAGRFSEDEARFFFQQLISGVSYCHSMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSQPKSTVGTPAYIAPEVLSKKEYDGKIADVWSCGVTLYVMLVGAYPFEDPEDPRNFRKTIGRILSVQYSIPDYVHISVECRHLLSRIFVANPAKRINIQEIKNHEWFLKNVPADLVDLADRSYHFEDPNHPPQSIEEIMRIISEAKIAGTGTGNYFGDPIDDMDINDDVDVDPDVDSSGEFVCAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPW9</accession>
    <name>A0A8T0HPW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG112800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13345" checksum="9D48B474F7D6B8A7" modified="2022-10-12" version="1">MDSEEVNTTLAVLSQPSGSRRRPRDEEPTEPIRHRRIPSSRSFVLVLEVEPAGEGRPEGVFAGRFHNEATEVQAWSQVKGAGHYQWLQGPMSHLPRARQLEYIAETMRQLFDFLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQA1</accession>
    <name>A0A8T0HQA1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">phosphoethanolamine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG149000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N,N-dimethylethanolamine phosphate + S-adenosyl-L-methionine = phosphocholine + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25325"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:295975"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:25326"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:25321"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57781"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58641"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.103"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:25322"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Phospholipid metabolism; phosphatidylcholine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.103" evidence="5"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000234">
        <property type="term" value="F:phosphoethanolamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44307:SF2">
        <property type="entry name" value="PHOSPHOETHANOLAMINE METHYLTRANSFERASE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0573102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13508" checksum="C43B752D3F33DB39" modified="2022-10-12" version="1">MKWLKPGGYIFCRESCFHQSGDHKRKNNPTHYRQPSGYTKIFEQTHVEEADGSFYEFELVGCKCVGTSAIEFENHKLVSIDTRQEFIKVDLTTSFSNLKLTQNESKLCDSKAPDESY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQD0</accession>
    <name>A0A8T0HQD0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG145000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19263" checksum="EE08A07BDB1F8D05" modified="2022-10-12" version="1">MKTDLRMDQQERTEDEGVDFAFWVGEAPRASRTGSTSKSRGSNAEMLSACFCARFANCSSNVEINAILSSVLAMGKCRMSSSCFWMSSRTGFACFAPEKGAAGVGDATSDTASTLPHATRYEDPGRPPGMTAGKSAKTGFDCKGGDAPRDGRTDSAALDDLDKETLGFWLLDIPEYPLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRV3</accession>
    <name>A0A8T0HRV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glyceraldehyde 3-phosphate dehydrogenase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG183400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRV3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF132">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase catalytic" evidence="3">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0573499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8089" checksum="F2409C331405FD46" modified="2022-10-12" version="1">MKGILGYTELDCASTDFIGDSRSSILDVKAGLALDNGFLKFVAWFDNEWGYSHKVVDLIVHMASLQHSPFYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRX6</accession>
    <name>A0A8T0HRX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG187200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="209" mass="22486" checksum="D9B5C750D4CD587D" modified="2022-10-12" version="1">MTPTNLIAFSVSTKTPKPYFVGITHLRSTVVGIAPNSPVDICFFLAVVEVELYLVVHIASCCSTAPHAPTSPRRRLVSCLPRQTLVKAALVISVGITSLLAVLCRSASIDTSGCPAAWSVRSMVVVALLLIRTAIPPYSTASPTATLSCHRSLLSRPWHTSVNPFLVILKYAFPSPVRSRRLPADIPRPRAAMESCANLQPDQGKISTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HST9</accession>
    <name>A0A8T0HST9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG211000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HST9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12602" checksum="9B906EF8954109B4" modified="2022-10-12" version="1">MWSAFFTTSSKHAIKNLIHASTKNITQDNFVKASKSNTPTRSTSCSCLLKCLLPNLVICGSFLIVLQNLICLYLLKLLLFLCISFVHVWMPLLCQLILSRFYFFWTSSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTQ2</accession>
    <name>A0A8T0HTQ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG245500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTQ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="316" mass="34636" checksum="BB0B89B0E9FC7B0B" modified="2022-10-12" version="1">MYNPVNEGTVPYTTPPTHLPPEMMPRTSLPDTSAEHIIRSETMVTGMQNPRSSPSVVECDAASEPPPTVQRCASVARIHLNELSTPSWASGETVPVTPSRLLQNFTNKMPIGTAVSTDVFASMGTTSDEKSPRLSPFTRPRSSVCLDALTECPSTSSQQCPNTNTVTDPAPNGETTRGMSIVAKKTTKIRPPRMRFELTLSPRMTSHALAANSLCYILHPTCGKTIVAEGRARGSWKCPSGKYGVLCAEGQQMVQVHKIIVPNLPLMHIEERHNLKTLDQALVKPLGSNVYVKWDTRLLWRRNKIPRAPPSASEKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV37</accession>
    <name>A0A8T0HV37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG273600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="CDD" id="cd13971">
        <property type="entry name" value="ADCK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044095">
        <property type="entry name" value="ADCK2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052402">
        <property type="entry name" value="ADCK_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 2 (PREDICTED)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45890:SF20">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="280"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0574581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="641" mass="72461" checksum="A9A10BD5A85E1E36" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVI0</accession>
    <name>A0A8T0HVI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Casein kinase II subunit beta</fullName>
            <shortName evidence="5">CK II beta</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG284000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Plays a complex role in regulating the basal catalytic activity of the alpha subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the casein kinase 2 subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1820.10:FF:000002">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.20:FF:000003">
        <property type="entry name" value="Casein kinase II subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1820.10">
        <property type="entry name" value="protein kinase ck2 holoenzyme, chain C, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016149">
        <property type="entry name" value="Casein_kin_II_reg-sub_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035991">
        <property type="entry name" value="Casein_kinase_II_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000704">
        <property type="entry name" value="Casein_kinase_II_reg-sub"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11740:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01214">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00472">
        <property type="entry name" value="CASNKINASEII"/>
    </dbReference>
    <dbReference type="SMART" id="SM01085">
        <property type="entry name" value="CK_II_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57798">
        <property type="entry name" value="Casein kinase II beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01101">
        <property type="entry name" value="CK2_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="41"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0574705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="300" mass="33770" checksum="D2040F0BC8DC6917" modified="2022-10-12" version="1">MFKERSSSLAAEVRGANVRGGESLYRDITDNKKQLEDGIEKSSPSTSKGGFSSEKDRIAAAVTMKQTRRNSGHEDRPALEKAKYPDDVVAEDSESESEDSDVSGSDGEDTSWISWFCGLRGNEFFCEVDDEYIQDDFNLSGLINQVPYYDYALDLILDVESPSDDILTEEQNDLVESAAEMLYGLIHVRYILTSKGINAMLEKCKNVDFGRCPRVFCSGQPCLPMGQSDVPRTSTVKIFCPKCEDIYYPRSKYQGNIDGAYFGTTFPHLFLMTYPYIKPLKPTQSYTPRIFGFKLHKSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVS0</accession>
    <name>A0A8T0HVS0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG320900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37646" checksum="27810FC590DF6249" modified="2022-10-12" version="1">MRHCNHKFHITCIAKAALINKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTASNAELDDLSWMTHDYEVEMRAREIPDAKEREFFCRNFGGHWSIHGNRFFRFPKPEVVVDADGKRREVERDYGQLDEYKMYDRTPVGRALVLAKLEEAIQHRRTFTEESFKYLDLDYWVIIKKSDDALQKIVCDKRRALRAEDNSSRWSRTRIEKIVQETVAKIEKAKELWDGKNSKKRNRDGPFEDDPEWGEDNRREVVAVEEEYRLGGTITRPSQRRFTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYR1</accession>
    <name>A0A8T0HYR1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G029400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035944717" evidence="1">
        <location>
            <begin position="26"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="9340" checksum="85CF73832ADD1817" modified="2022-10-12" version="1">MVEHLGWSRFLVARARLAWVARFLGWSMVVDEVQWGGSYSHKRWAFRWPWRQLMVRQMRASVLHNLSPELNDTLKSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZB3</accession>
    <name>A0A8T0HZB3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 16">Arginine decarboxylase</fullName>
            <ecNumber evidence="6 16">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_5G044300</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the biosynthesis of agmatine from arginine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 16">
            <text>L-arginine + H(+) = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="6 16"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZB3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:L-arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.37.10:FF:000062">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040634">
        <property type="entry name" value="Arg_decarb_HB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041128">
        <property type="entry name" value="Arg_decarbox_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003763">
        <property type="entry name" value="PRK05354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="ARGININE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295:SF9">
        <property type="entry name" value="BIOSYNTHETIC ARGININE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17810">
        <property type="entry name" value="Arg_decarb_HB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17944">
        <property type="entry name" value="Arg_decarbox_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 16" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="13 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="10 15 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 16" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="17">
        <location>
            <begin position="182"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Arginine decarboxylase helical bundle" evidence="18">
        <location>
            <begin position="478"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Arginine decarboxylase C-terminal helical" evidence="19">
        <location>
            <begin position="683"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="600"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="15">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU003740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF17810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF17944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0575965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="759" mass="82891" checksum="2EB3004008B5B646" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3D5</accession>
    <name>A0A8T0I3D5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G195600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3D5"/>
    <dbReference type="OrthoDB" id="1932331at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8298" checksum="889358CAF11B0A2B" modified="2022-10-12" version="1">MPEWLSGMTRNHVGFARAGSNPAEHRRRRECSDHDEAQGQHQTPAPLRPQHQLLDHEPEDQLAKPHYQRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4L5</accession>
    <name>A0A8T0I4L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 12">Mitogen-activated protein kinase</fullName>
            <ecNumber evidence="2 12">2.7.11.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G157900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Activated by threonine and tyrosine phosphorylation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.24" evidence="2 12"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4L5"/>
    <dbReference type="OrthoDB" id="192887at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004707">
        <property type="term" value="F:MAP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07852">
        <property type="entry name" value="STKc_MAPK15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000238">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000166">
        <property type="entry name" value="Mitogen-activated protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003527">
        <property type="entry name" value="MAP_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01351">
        <property type="entry name" value="MAPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="13"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0577463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="44564" checksum="08FC91392724025E" modified="2022-10-12" version="1">MCEDIDKHVLRKYHVGQKLGKGAYGIVWKAVDRRTNEVVALKKIFDAFQNSTDAQRTFREVMFLQEMNDHENIIKLFNVLKAENDRDLYLVFEFMETDLHAVIRANILEEIHKQFIMYQLFKALKFMHSGELLHRDIKPSNLLLDSECQVKLADFGLARSVAQLKEDAGNAQVLTDYVATRWYRAPEILLGSTQYTFGVDMWSSGCILGELLNGKPVFPGTSTMNQIEKILEVIGRPAPEDIAALQSPFAATMLENMPINTKPFHNVFPKASSEALDLLKKLLHFNPYKRMTAEEALRHPYLAQFHNPSDEPICNRIVRIPIDDNTKFTINEYRERLYAEIVRRKKEIRRKNRENERLGREMSRAQRRPSKLHSSGSASESRDCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5D6</accession>
    <name>A0A8T0I5D6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SURF1-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G180200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Probably involved in the biogenesis of the COX complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Mitochondrion inner membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SURF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5D6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd06662">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002994">
        <property type="entry name" value="Surf1/Shy1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045214">
        <property type="entry name" value="Surf1/Surf4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23427:SF2">
        <property type="entry name" value="SURFEIT LOCUS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02104">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50895">
        <property type="entry name" value="SURF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="358" mass="39853" checksum="133F1FEC7D1EB816" modified="2022-10-12" version="1">MAARLMWRSGGGRGAVRTLQLQRVLGFSTSSAAVGPAGEISAAASSLHSQEAGKKWGLSVLVLILPCAATFGLGSWQLVRREKKIELLDFRRARFEEDPIALEEALAIKRQSVDNAQSDVLQYRKVYCEGVLDESKSLFVGPRSRTLYGAAEKGYYIVTPLICKSSSDTRVQLPVLVNRGWVPSSMRNEAMAQEQAVHEQPAHAVVKDVEEANIKETKQSSWWSRWGKPQVADQEEVTVAEPERPIVRVAGVIRDGEQPNMFVPNNQPEIGQWFYVDVPAMARVMGLPEDVTYMEAVATSSPDREGRKKFPLPKESDSFLKSSVMPQDHLNYALTWYTLSAATSFMAVKRLQNLKRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8E2</accession>
    <name>A0A8T0I8E2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G042800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8E2"/>
    <dbReference type="OrthoDB" id="25818at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF50">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="249" mass="26544" checksum="163021DEE7ED2EB1" modified="2022-10-12" version="1">MAARALYTVGFWIRETGQALDRAGCRLQGNYIFREEVARHKPLMNLFDKKPSVAEDAFVAPSASLVGDVQVGSKSSIWYGCVLRGDANSIRIGSETNIQDHSLVTVGGSRFSGGNAPTIIGNKVTIGHSAVIHACTVEDGAFVGMGATLLDGVVVEKGAFVAAGALVTEKTRIPAGQIWAGNPAKFLRNLKDDEGAFIPKSAENYSEVAAAHADANAKRFHELTTVQEVKTEEVKTEEKCPELTPQASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC56</accession>
    <name>A0A8T0IC56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G144900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046349">
        <property type="entry name" value="C1-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004146">
        <property type="entry name" value="DC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31479">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31479:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03107">
        <property type="entry name" value="C1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57889">
        <property type="entry name" value="Cysteine-rich domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="DC1" evidence="4">
        <location>
            <begin position="521"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="DC1" evidence="4">
        <location>
            <begin position="580"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="424"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="444"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0580073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="637" mass="72335" checksum="0DC4270CDA426810" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDA2</accession>
    <name>A0A8T0IDA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G004500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDA2"/>
    <dbReference type="OrthoDB" id="1937997at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19502">
        <property type="entry name" value="RecA-like_PAN_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000005">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000037">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048723">
        <property type="entry name" value="OB_PRS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21236">
        <property type="entry name" value="OB_PRS7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="200"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0581734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="425" mass="47566" checksum="D803666DB5766389" modified="2022-10-12" version="1">MADIADDLLKEKNPPPLDEDDIALLKTYGLGPYANLIRKTEKDIKDMAKKVNDLCGIKESDTGLAVPSQWDLVSDKQMMQEEQPLQVARCTKIINANTDDSKYVINVKQIAKFVVGLGEKVSPTDIEEGMRVGVDRNKYQIQIPLPPKIDPSVTMMTVEEKPDVTYNDIGGCKEQIEKMREVVELPMLHPEKFVKLGIDPPKGVLCYGPPGTGKTLLARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFQMARSKKACIVFFDEVDAIGGARFDDGSGGDNEVQRTMLEIVNQLDGFDARGNIKVLMATNRPDTLDPALLRPGRLDRKVEFGLPDLESRTQIFKIHTRTMNIERDIRFELLARLCPNSTGADIRSVCTEAGMYAIRARRKTVTEKDFLEAVNKVIKGYQKFSATPKYMVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFY3</accession>
    <name>A0A8T0IFY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Sulfite exporter TauE/SafE family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G252700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255">
        <property type="entry name" value="CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255:SF3">
        <property type="entry name" value="SULFITE EXPORTER TAUE_SAFE FAMILY PROTEIN 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="426"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="495"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0581448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="566" mass="61928" checksum="6C794558BA09F518" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHJ6</accession>
    <name>A0A8T0IHJ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b6-f complex subunit V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G119000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009512">
        <property type="term" value="C:cytochrome b6f complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00432">
        <property type="entry name" value="Cytb6_f_PetG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003683">
        <property type="entry name" value="Cyt_6/f_cplx_su5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036099">
        <property type="entry name" value="Cyt_6/f_cplx_su5_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02529">
        <property type="entry name" value="PetG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000034">
        <property type="entry name" value="Cyt_b6-f_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103446">
        <property type="entry name" value="PetG subunit of the cytochrome b6f complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0583220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="40" mass="4289" checksum="0E3F3E50EF70F65D" modified="2022-10-12" version="1">MVEALLSGTIGIVLGVIPITLVGLFVAAYLQYRRGDQLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILB1</accession>
    <name>A0A8T0ILB1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Snurportin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G180100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the snurportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILB1"/>
    <dbReference type="OrthoDB" id="10003593at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061015">
        <property type="term" value="P:snRNA import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09232">
        <property type="entry name" value="Snurportin-1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017336">
        <property type="entry name" value="Snurportin-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047857">
        <property type="entry name" value="Snurportin1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13403:SF6">
        <property type="entry name" value="SNURPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13403">
        <property type="entry name" value="SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21974">
        <property type="entry name" value="SPN1_m3Gcap_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Snurportin-1 m3G cap-binding" evidence="11">
        <location>
            <begin position="117"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF21974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0584032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="434" mass="48343" checksum="4123A6701D50350A" modified="2022-10-12" version="1">MAGTTLVPPGRHHKRTVSDQQKRRELALQRQKQGRRDLQHHARQLALNAPNEEQPVDLAEVNSAGSASEDAVFDYSERDEAEIGMEDAESSPESKRAALLEGARLKGLRAREFFSRQLMLPEWMVDIPPYLKKDWFIMPRPEGQRCLVISANGVTLSRQRNGRILHSFPSALPNGARTKEVAAGSHVYCILDCIFHAPDKTYYVIDMMCWRGYSLFDCTAEFRFFWMTTKLAETGALCDPSAHHHYRFSVVPVYECNVSGLQAVYSGPVPFVRDGILFYNRHALYELGVTPLVLVWKDAQCSQYLLDTDSHGNVPAYQQVVLELNSDGSVVTSDDPPVTLGALAPDFLEQNALHVRPGMLLRFAIGDQGLSLVEGKPVVADIHFQGVANKNRARRADTCTKILFQYAARHGALTVNDLLAAIEASDEEGDTSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILY7</accession>
    <name>A0A8T0ILY7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G169300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILY7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035828538" evidence="1">
        <location>
            <begin position="32"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="34334" checksum="0EEAEDCC6FD904F0" modified="2022-10-12" version="1">MATSAGYRDAFAALLLVALVVLAAGTQSASATRSYGRHEPRSMRAKVRNHMKKETCVMNGVAVPPGATREVEVTRVKLTITVKVVVKGKSRPVYTMPVSRDSWAAGRDFLLEINDCSACRNCAGCSAGLLCLRVTIKGRERARVCPIRIGAPGGATPPPPPPPVVLPPVVLPPVVPPVAAPPVTLPPVTLPPVALPPVAVPPVAVPPVAVPPVALPPVVVPPLGPILAPIVDPLVPIVAPITAPLGPILAPIVDPLVPIVAPITAPIAPILAPVVNPLAPIVAPITAPLGPILAPILAPAVTPIVAPIVAPLAPILSPILTPITSPILPPLIGIPGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM92</accession>
    <name>A0A8T0IM92_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G243400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM92"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004713">
        <property type="term" value="F:protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000103">
        <property type="entry name" value="PTI1-like tyrosine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052101">
        <property type="entry name" value="Plant_StressResp_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47983:SF3">
        <property type="entry name" value="OS05G0135800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47983">
        <property type="entry name" value="PTO-INTERACTING PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="73"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="42"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0584894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="366" mass="40144" checksum="9959DFC0E5C68B24" modified="2022-10-12" version="1">MGWCCCSAEEEDFNKVSNDAHNQFSGHNGNPGHQGNQRPQGDQPQRAGQAQRLQPIAAPQLSIDEIRECTDNFGPKSLIGEGSYGRVYYAQLQDRVAAIKKLDASAQPDSEFLSQVSLVSRLKHENVVELIGYCLDGQLRVLAYEYATMGSLHDILHGRKGVKGAQPGPVLDWMQRVKIAVGAARGLEYLHEKAQPSIIHRDIKSSNVLLFDSYVAKIADFNLSNQAPDMAARLHSTRVLGTFGYHAPEYAMTGQLTQKSDVYSFGVVLLELLTGRKPVDPTMPRGQQSLVTWATPRLSEDKVKQCVDPKLRSEYPAKAVAKMAAVAALCVQYEADFRPNMSIVVKALQPLLTARPAPQAGGFQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMC5</accession>
    <name>A0A8T0IMC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G184200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12866" checksum="1476DA2CE7D6D70B" modified="2022-10-12" version="1">MTGCKNLQKLPTSIGNLKGLRRFMLRDCGSVEAMGALTTLQGLPMWGTTSVTELPASLGLVSTLLAYGDSLQYYEREYTGFVGTSQVLEEDESGFLKAYHDESSGVTILVRGIHEIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMU6</accession>
    <name>A0A8T0IMU6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Polymorphic outer membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G204600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003368">
        <property type="entry name" value="POMP_repeat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01376">
        <property type="entry name" value="POMP_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02415">
        <property type="entry name" value="Chlam_PMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0584345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="476" mass="50673" checksum="0E258FFE2E217525" modified="2022-10-12" version="1">MCKAHRDAGLVRKMGERRAPAVLAAAVLVVVFTLLGQVSSGVISWDSVGQLEEKFMRRHKLRESRRLKALNERMNVSSYGLYPQLTQQIRCQQVIDQARDQEISPSSQTCSDDACLVEAMYMKTPLLTIDRDIDISNSLPLPTITTKMTISGKCHDHPCIIDAFGLGQIFVVGIGGHLTLQNLEIKSGYYSEGGAAVTVMGSSGSSAHPSGKLLALNVLFFNNSASGNGGAVLVKKGGALHVQNSVFDSNEASMGGAVYVQSSDDMDADCSLSSSCANFIGTAFMGNWADLGGAIYVNNAANSCIQPGKFECTTCSFNNNLALDDGGAIYMAGKHRGAMGNVKFSNFYNNTVEVASQLTGGAVAIEAGEPGGFGVEFNSFDSIYSQSFDNEISISVKAFANATLVYSKFLTNNTVACYGACNFCPTLSKSLYLANCSTLLPTPNPTSPKICPQLPPRICDWIPLKCNLPTSAPTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN15</accession>
    <name>A0A8T0IN15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G262100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IN15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001080">
        <property type="entry name" value="3Fe4S_ferredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44579">
        <property type="entry name" value="OS01G0730500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44579:SF2">
        <property type="entry name" value="OS01G0730500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13370">
        <property type="entry name" value="Fer4_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00352">
        <property type="entry name" value="3FE4SFRDOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="82"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="290"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="305"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="349"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="363" mass="40517" checksum="848DA5C19BE1FD59" modified="2022-10-12" version="1">MAACQATLPLTSASRIPTQTPEVTLIGNSRACSARLRPQSIRNLFRIKEAPACKKTISCFAARARLGGDGDVDLNGDPVAEDFYSVLGLTPDATPEEIKKAYYSCMKTCHPDLSGNSQDATDFCMFINEVYEVLSDPEQRMVYDEINGYALTSVNPFLNPRGQERDHAFVDEFTCIGCKNCANTAPDTFEIEDEFGRARVFCQLGDVRSAQEAIDTCPVDCIHWVTAAQLTLLEDEMRRVERVNVGMMLAGMGGQSPDVFAQASWRWEKRQAKALDRARIRMMKEKGNDAPGSWWQGWATPGGDENYRPDDMGARERAAKTAAATRRWREYSRQTSNRKSAFSLPSQSRSEDESESKKETVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INF2</accession>
    <name>A0A8T0INF2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G000800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INF2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="14104" checksum="015DFDA9B84B3869" modified="2022-10-12" version="1">MSLRVLHEVSHQLNFPDILKLQEQLSILLVHLISLLISKKSILYTRLGQTRPMSSSRAHYSHQSYALRIQLQRQTNGLNEILTVKCIRTWNLSCNASSKRYQDHCTSPEQSEREPPRHAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INJ7</accession>
    <name>A0A8T0INJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G217800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035862512" evidence="1">
        <location>
            <begin position="19"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="14368" checksum="6D446C30869D64D5" modified="2022-10-12" version="1" fragment="single">MATRLITGEALLWSSSLSLSLVQDPEANVLRAQIHQKLTQLHLHHKRLPFNRNASRTRREYALMRVNIHKHAELPGYVKRSPTRPGSKQNKLRRNLDKILLHNSDLGYKWLQTTVVMPSYAPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPY6</accession>
    <name>A0A8T0IPY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Chloride channel protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_3G227400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the chloride channel (TC 2.A.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034707">
        <property type="term" value="C:chloride channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00400">
        <property type="entry name" value="Voltage_gated_ClC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3080.10:FF:000008">
        <property type="entry name" value="Chloride channel protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3080.10">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="ClC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050368">
        <property type="entry name" value="ClC-type_chloride_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43427:SF3">
        <property type="entry name" value="CHLORIDE CHANNEL PROTEIN CLC-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="Clc chloride channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0129">CBS domain</keyword>
    <keyword evidence="12 15" id="KW-0868">Chloride</keyword>
    <keyword evidence="11" id="KW-0869">Chloride channel</keyword>
    <keyword evidence="13" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8 15" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="388"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="470"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="512"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="582"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="616"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="17">
        <location>
            <begin position="737"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="17">
        <location>
            <begin position="823"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="179"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="110"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU361221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0584678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="910" mass="97326" checksum="7825FF58378FC160" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQZ7</accession>
    <name>A0A8T0IQZ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G024500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase zinc-binding" evidence="1">
        <location>
            <begin position="43"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="29746" checksum="6C139080BBE8BEF0" modified="2022-10-12" version="1">MIHQKHTCEKFTALKGRKLLSPRTCLTRPINLKWAGQVPLNFQPDWKAVWSSSRPRKEAAFLWSLIHKAVAVNEWRHRAIPAISALCDGCTSGTPETILHCFYACEPAARAWHFAATVLHLSARSPWSPSPRPLPTWDQCILGVDLPNELQESQVLWSLIRGATLWVIWIQRNQRVFHNNLWPVTVLEQQLWDAFLDLAHVAWNKISWCEENQPQGITRATEEFRTTWLPVGLFFTLTERGPRWNYQRPPTDLFLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR78</accession>
    <name>A0A8T0IR78_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G020500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR78"/>
    <dbReference type="OrthoDB" id="550575at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057207">
        <property type="entry name" value="FBXL15_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926:SF5">
        <property type="entry name" value="F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38926">
        <property type="entry name" value="F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25372">
        <property type="entry name" value="DUF7885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="F-box/LRR-repeat protein 15-like leucin rich repeat" evidence="3">
        <location>
            <begin position="431"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="581" mass="65260" checksum="1F8F1960DA71BDA5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS88</accession>
    <name>A0A8T0IS88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G048500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689">
        <property type="entry name" value="HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43689:SF14">
        <property type="entry name" value="LYSOPHOSPHOLIPASE BODYGUARD 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="234"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="513" mass="57959" checksum="9B29F7521C7ADFEC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVB8</accession>
    <name>A0A8T0IVB8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G104700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVB8"/>
    <dbReference type="OrthoDB" id="525163at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34687">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34687:SF1">
        <property type="entry name" value="CHAPERONE PROTEIN DNAJ-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="10181" checksum="C017042283DC9152" modified="2022-10-12" version="1">MSPGVVTVVQGLSALAGAWVIKSILDAEQEKPMGGFSQCPTCNGSRRVPCMCTRWSDNDVGCSTCEGSGRMRCNSCGGSGTGKPIPVQVRASNPSRNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWK5</accession>
    <name>A0A8T0IWK5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent helicase ATRX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_2G155700</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Telomere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000781">
        <property type="term" value="C:chromosome, telomeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11726">
        <property type="entry name" value="ADDz_ATRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.850">
        <property type="entry name" value="SWI2/SNF2 ATPases, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025766">
        <property type="entry name" value="ADD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041430">
        <property type="entry name" value="ADD_ATRX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044574">
        <property type="entry name" value="ARIP4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797:SF1">
        <property type="entry name" value="HELICASE ARIP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45797">
        <property type="entry name" value="RAD54-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17981">
        <property type="entry name" value="ADD_ATRX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51533">
        <property type="entry name" value="ADD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0779">Telomere</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="20">
        <location>
            <begin position="674"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="942"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="1355"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="99"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="505"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="17">
        <location>
            <begin position="120"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="519"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00031106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0587319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1728" mass="193482" checksum="5B63F81B1777A7EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX65</accession>
    <name>A0A8T0IX65_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G129600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX65"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="180"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="313" mass="34401" checksum="95DCCB58774BC04C" modified="2022-10-12" version="1">MDVVNGEIVSASTEWSIAEAWSALQPSLGRTMESSMSGSFDYLLAGNGSDWNVASPASFCSIERPFSAWGGCGVAPGHDPRPNSLALEPRAARWPSSRPLVEKHHHVGAFREFGGMQPRPNVEHHRQGWGTGVKRHFHFSPKLPLLQPDSATDLDQMLEMYESQTTQLVPGRLTSCASASSALGQADQSPTLPSSVGNSRELSLQRSGSLQEREAQSYPNSTLVSFVKRKRMRTSFSDKADVQLDCSWSHPLNLLLQKGLSSTDVGDLGRIIIPKASYMSREFGQEWETSNVSWGFGSNFMQCLLCHCKNDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXQ0</accession>
    <name>A0A8T0IXQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G192500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Centromere</location>
            <location evidence="1">Kinetochore</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mis12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000444">
        <property type="term" value="C:MIS12/MIND type complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051382">
        <property type="term" value="P:kinetochore assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000070">
        <property type="term" value="P:mitotic sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008685">
        <property type="entry name" value="Centromere_Mis12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14527:SF2">
        <property type="entry name" value="PROTEIN MIS12 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05859">
        <property type="entry name" value="Mis12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="9" id="KW-0137">Centromere</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0995">Kinetochore</keyword>
    <keyword evidence="5" id="KW-0498">Mitosis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="124"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0587802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="219" mass="24396" checksum="E0B4C7190C85736F" modified="2022-10-12" version="1">MKRPTTSSPLTPSTSSISTRTPSPPRSSMPCVHFVAFQVIEISMNRFTEMETYATRMLKITSKESQEALQQGLSTVFEKFLSKFVEEDLGPWETYCKEACLKVPAGLVLPEKFDASSNLCEDEDVKLDAELNSLRERKAAAEKETAELRRDIKALEAHVEAKASFMDAFDQLQNLPLIDDLGTAVRDLRKSVEEANALRAQRYQKLLFPANPSASGDSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXS7</accession>
    <name>A0A8T0IXS7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Subtilisin-like protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_2G169100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXS7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02120">
        <property type="entry name" value="PA_subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000006">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041469">
        <property type="entry name" value="Subtilisin-like_FN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17766">
        <property type="entry name" value="fn3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035749813" description="Subtilisin-like protease" evidence="9">
        <location>
            <begin position="30"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="11">
        <location>
            <begin position="35"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="142"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease fibronectin type-III" evidence="12">
        <location>
            <begin position="678"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0587501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="780" mass="83215" checksum="F7D419E913A5D139" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXY6</accession>
    <name>A0A8T0IXY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G196200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050913">
        <property type="entry name" value="AP2/ERF_ERF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194:SF192">
        <property type="entry name" value="OS02G0797100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31194">
        <property type="entry name" value="SHN SHINE , DNA BINDING / TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="91"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="203"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0587852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="222" mass="24580" checksum="208241429D76AC4F" modified="2022-10-12" version="1">MGRPQRYRGVRQRHWGSWVSEIRHPLLKTRVWLGTFETAEDAAHAYDEAARLMCGVRARTNFPYDPNAPKGPNSQMLSATLSAKLHRWYLQSQQQEGQPGSNKASSKDNARSIQTQSLTCLCLDAEQSNLGIWQKKTGRQANDSANWVRKVQFGDSAASLFEPQPQPANSSESCMSEEDKFAAEMIEELLGHSPGQFFDFSSPAMSDSSCSSPCSGITATSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYA4</accession>
    <name>A0A8T0IYA4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G206000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYA4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11873" checksum="88828D11E52FD42B" modified="2022-10-12" version="1">MPGYRQVMNDIMIRILVWMCVRSSAGYSVRLGLGYGRVWRRLLGPVRRISVGQFQGSMALFTVYLCESSNICCRSMWMTLFMRFDKQEDVHECAEVYFPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYY2</accession>
    <name>A0A8T0IYY2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G216500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYY2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035762224" evidence="2">
        <location>
            <begin position="30"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="13028" checksum="91F066CD33863A90" modified="2022-10-12" version="1">MATITSSGAISLVLLGFLLSHSLLQPVTASLPLSENDNSPVHEASGIRAVISRKLVAFQKWYGGGGCDSCGNGGYNNGPGYGYGPGYGYGNGPGYGNGPYHRGRGGGGGGGGGGGGGGGGGGGGGGGGGGRRKLLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZB5</accession>
    <name>A0A8T0IZB5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G234300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="11886" checksum="DBECC7FBC9D714CA" modified="2022-10-12" version="1">MPPPCLPLGIVLLSCRDGYQGHPGHPQDGGSFSGSVHQGHGSLPPEHGAVAQPSPCIQGAQHCERAGSLPLPRRERPCFHASTANQWLEGQLNGWRSAECIRRTLIQAPAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZM3</accession>
    <name>A0A8T0IZM3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G236000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZM3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07425">
        <property type="entry name" value="MPP_Shelphs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041787">
        <property type="entry name" value="MPP_Shelphs"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47680">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47680:SF2">
        <property type="entry name" value="SHEWANELLA-LIKE PROTEIN PHOSPHATASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="82"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="413" mass="44458" checksum="C107553B9DED632B" modified="2022-10-12" version="1">MPAMAEALHKEPALCGQVPSLFSSFVDSFVDYAVAGQVLGKPAVPPSVETNALDAAFTKLDVAPPVVGHGDGLRTWLPAAKRLIAIGDIHGDLAKARAALQVAQVIDEHDRWVGGETVLVQVGDLFDRGGDEIKILYLLEKLRGEAQKAGGDVHVMNGNHEIMNIEGDFRYATRAGLEEFRGWAHWFSLGNILKSKCAGLGQQVDIFHGIPDSYPPGLRARMAAMRPGGPLASRFLSKHPVVLVVGSSVFVHGGLLPEHVNYGLDRINDEVSDWMLGTKGWKGPGYLHGADALVWTRKYSDVTESRCDCELLTRCLRSIDGVKRMVVGHTIQQPVGLNGACDNKVIRVDVGLSKGCADGMPQVLEIRGDKELRVLSSRLPPSLIDAGAENGGFALKEKSGLASLLVQAPQRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZS4</accession>
    <name>A0A8T0IZS4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G005300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZS4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12533" checksum="879EB8AE57733AA7" modified="2022-10-12" version="1">MGFLFSAILESQVALRRSMSQWDRRFSLVARPNNTCVRTIEPTRENDSWSKCLQCKDPQCIPITRASPQRLSLFKMPLRELPNFQPQSTSSLNDEKLAKRPKPQILQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J253</accession>
    <name>A0A8T0J253_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G038900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J253"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5927" checksum="FA6871C243753546" modified="2022-10-12" version="1">MQSILAMGAYHFCAALLYICTNSLVPECSKTRLERGETLKICTAQKVWFASEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3H3</accession>
    <name>A0A8T0J3H3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G039300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3H3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010326">
        <property type="entry name" value="EXOC3/Sec6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06046">
        <property type="entry name" value="Sec6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11292" checksum="43DE18176D31BE7C" modified="2022-10-12" version="1">MMRNFEGFMNCMLVQRMCSNILDADKVNPPKRAESGRLWTPAGVDLFRLLNEQVKVVQETSTDVMLFHVAVAINQVWSFDVSWKSKVDGSVLGFGTWYC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4Q8</accession>
    <name>A0A8T0J4Q8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcription initiation factor TFIID subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G133500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004402">
        <property type="term" value="F:histone acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17064">
        <property type="entry name" value="Ubl_TAFs_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000223">
        <property type="entry name" value="Transcription initiation factor TFIID subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.10">
        <property type="entry name" value="Bromodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1100.10">
        <property type="entry name" value="TAFII-230 TBP-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001487">
        <property type="entry name" value="Bromodomain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036427">
        <property type="entry name" value="Bromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018359">
        <property type="entry name" value="Bromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040240">
        <property type="entry name" value="TAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022591">
        <property type="entry name" value="TAF1_HAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009067">
        <property type="entry name" value="TAF_II_230-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036741">
        <property type="entry name" value="TAFII-230_TBP-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041670">
        <property type="entry name" value="Znf-CCHC_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13900:SF0">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00439">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12157">
        <property type="entry name" value="DUF3591"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09247">
        <property type="entry name" value="TBP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15288">
        <property type="entry name" value="zf-CCHC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00503">
        <property type="entry name" value="BROMODOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00297">
        <property type="entry name" value="BROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47370">
        <property type="entry name" value="Bromodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47055">
        <property type="entry name" value="TAF(II)230 TBP-binding fragment"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00633">
        <property type="entry name" value="BROMODOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50014">
        <property type="entry name" value="BROMODOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0103">Bromodomain</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="736"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Bromo" evidence="10">
        <location>
            <begin position="1967"/>
            <end position="2037"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="97"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="155"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1279"/>
            <end position="1438"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1456"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1608"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1714"/>
            <end position="1737"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1771"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1864"/>
            <end position="1942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="195"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="250"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1282"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1295"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1305"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1339"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1351"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1394"/>
            <end position="1404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1415"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1667"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1714"/>
            <end position="1733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1864"/>
            <end position="1889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1914"/>
            <end position="1927"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0590894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2089" mass="236560" checksum="26E64E730E2EDBF0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J696</accession>
    <name>A0A8T0J696_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G105600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J696"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13432" checksum="8CB8A319FF9B66B8" modified="2022-10-12" version="1">MPDRNTHRKRHPLNHSPAATTFPAQHNHSQRVILQHQFQKPHRKNSSITSRTKTPPAFKQQPLHSPHPTISRTQKSPKGSPQHATQSRFHSHTETARKKTIRSCKESTACSISKERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7C6</accession>
    <name>A0A8T0J7C6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 6">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G203100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7C6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035961712" description="Carbonic anhydrase" evidence="6">
        <location>
            <begin position="27"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="7">
        <location>
            <begin position="78"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="36170" checksum="332F5BB2BEB019E6" modified="2022-10-12" version="1">MKKATAIHLAYAIAATHFVCTAVAMAQHHQFYAAAGPRVIIPERPLPLIPGPGGSWSPSSQPYENLLVSTPQEQASSVLFDYTDGPNGPDHWGELNADWSLCKSGAQQSPLAITPTLMITDSTLGDLKANYTSKPVNATISHDGLNLKVDVPSSAGELKIYNVTYRPASFHFHRPSEHRILNYSFPLELHLVHKSEDDRMAVIAWLFVPGSTNNSFLAQFLDELPSHKKPYANLEISPINLPTLEPNYGRYRGSLTTPPCSETVIWTVMLWNFPSVSDYQLKQLKSAMPRKNARPSFPSRGRKFRINHTPNWTLMKQAFKDNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7G4</accession>
    <name>A0A8T0J7G4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 and DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G155900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 2 heme b groups non-covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017214">
        <property type="entry name" value="UCP037471"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF171">
        <property type="entry name" value="OS01G0895300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037471">
        <property type="entry name" value="UCP037471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="11">
        <location>
            <begin position="65"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="12">
        <location>
            <begin position="185"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037471-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0591176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="404" mass="43643" checksum="AD78F073EEBD8D5E" modified="2022-10-12" version="1">MGGCGCGGSRVAVLGVVCAVITILSLALPTFGAATNPGCSADLSNKVTKFQTGSLKCKSYGFPTSNPYVIWALQDNVTQVATMVVSMPLSPNKWAGIGFSTDGQMVGSTALVTTLSSNGAPIIKVYSLNDRSQQGVVEDASKLTFVGGPPEGHYDQGRTVYISFQVDFTKSTAKANWFLMAFGSLYTDGSIDYHEQRNYFKASIVPGTVVGESAASKLEKKSKIHGSLQILGWGLLLPVGAMVARYARGFDPAWFYVHVTFQILGFACIIAGVATGIQLAKDFQPEHLQAHRGLGLFLFVLAILQVLAVAWRPKKDAKIRKYWNWYHGGVGRLALFLAVVNIFLGLSIGKAENDFKLGYIIILAIELLAFAILEVLLWLRWNRQPRGERSADQGVPGFQFGGSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J872</accession>
    <name>A0A8T0J872_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G176500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J872"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035783888" evidence="2">
        <location>
            <begin position="30"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="12149" checksum="D319F60391BBCA48" modified="2022-10-12" version="1">MAKFSHQSVAVLLAMVVFCVSMMAAPSSAQGPAESWPAPAPYMRGSPSSAPGYAPEFSPSYAPAWAPEYAPAWAPEYAPIGAPEGSPISAPIVASPAYSPSSGPSSFESPAYAPGPMSGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8L5</accession>
    <name>A0A8T0J8L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G236700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8L5"/>
    <dbReference type="OrthoDB" id="449052at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF101">
        <property type="entry name" value="SNF1-RELATED PROTEIN KINASE REGULATORY SUBUNIT GAMMA-LIKE PV42A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="308"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0592250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="372" mass="40547" checksum="591A1DDC8E1972F2" modified="2022-10-12" version="1">MAQVGEKVGVLRGTTVQQIVEHKHRLVEIPYMATVNDALTTLLAKNILAVPVAAPPGQWIGAGGSMILESDKVTGVVRKQYIGMVSVLDILIHIAEAEKEEDVDSRLKAPVSSIIGHSMEGLSLWSISPQTSVFEAMEPMSKGIHRALIPVESKMDHTIGVELMEASPGYHIFTQTDMVEFLYMHSKELDFMTNLSVLELGAVHPEVYAAPSCMKVMDVVKCMRKTSLQAVAIVESTGDLDNELALVRGNGRKLVGTFSASDLLGCTSEMLRAWATLPILSFFSKAGIAQRFGMGAAVNAGPFECRGFQKSPVTCHLQTPLAEVMSKALTSHVHRVWVVDNDGNLNGVVSFSDMIRVVHDFFSKHNPQADYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8R5</accession>
    <name>A0A8T0J8R5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhoD-like phosphatase metallophosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G186500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="entry name" value="PhoD-like phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37031">
        <property type="entry name" value="METALLOPHOSPHATASE BINDING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37031:SF2">
        <property type="entry name" value="PHOD-LIKE PHOSPHATASE METALLOPHOSPHATASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD-like phosphatase metallophosphatase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="614" mass="69006" checksum="2F9CFFB83912C8CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9S5</accession>
    <name>A0A8T0J9S5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G271300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9S5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6221" checksum="B34D8331D6E0E741" modified="2022-10-12" version="1">MGGASEFTPGSSGDGIFSGIRIWGRIFGQISGSHIHNGTILLPEYFNPKITTQSLSPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9X9</accession>
    <name>A0A8T0J9X9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Magnesium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G276100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Magnesium transporter that may mediate the influx of magnesium.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9X9"/>
    <dbReference type="OrthoDB" id="10251508at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12823">
        <property type="entry name" value="Mrs2_Mfm1p-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039204">
        <property type="entry name" value="MRS2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890:SF42">
        <property type="entry name" value="MAGNESIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13890">
        <property type="entry name" value="RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22099">
        <property type="entry name" value="MRS2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="507"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="543" mass="61766" checksum="266A57C12701BB4F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA18</accession>
    <name>A0A8T0JA18_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G185500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA18"/>
    <dbReference type="OrthoDB" id="2017571at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11454">
        <property type="entry name" value="bHLH_AtIND_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000053">
        <property type="entry name" value="BHLH transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045843">
        <property type="entry name" value="IND-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914:SF12">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914">
        <property type="entry name" value="TRANSCRIPTION FACTOR HEC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="304"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="78"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="48395" checksum="5ADAFB043318C5E2" modified="2022-10-12" version="1">MTLSLQRPDDRGGLRSMEKWSNSGWGNQHPILEPSMSPLFFPHQGLQSQSMFPQLVGSAEQQALVQAFVQQANAEHSMLDSTRAQRPRGTGSIDTLLKSSNSSSMVDSTSDDECTAPENLQMNCISSLGGGPMSPVLQANLLDRTASTGTSLMNAKDFFRMESPGGPLSPNALPRGESEDSLAGAEAVATFKRRLLEEDESEWLDQIHGARAKMAKVGVETFPLQQEPVDMAPFSDVPALTTIASVMPASSPFLQEAVGGAGNPSVDMDKLASMRAILFRHASQPVPSLEEIASTRPKRRNVRISKDPQSVAARLRRERISDRIRVLQRLVPGGTKMDTASMLDEAIHYVKFLKLQLQTLEQIGNNSNNDDPRGLVQQQPPSQLSSLVRPFDLNCTQAWPAPPTSMVNNLHHSQASLRQGLSTLWPSDANNAFSDAMQEQFCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB20</accession>
    <name>A0A8T0JB20_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G293300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB20"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="580"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="629"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="785"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="520"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="637"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="662"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="673"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="691"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="707"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="834"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="871" mass="96576" checksum="77C8773DCDCC17C0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBM4</accession>
    <name>A0A8T0JBM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G241200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044839">
        <property type="entry name" value="NDR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234:SF2">
        <property type="entry name" value="OS05G0199100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0592309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34745" checksum="0AA279FD877F74E3" modified="2022-10-12" version="1">MSSSGVSFFRKGESIAKRMWDARKPEVPLSSREHNTTEDSRQETLPLNAPSPETKLDHSHIIVESKPQPRLLRSSTHTNLLSTSINRLSTYTDYFTAHCCFICIWRTLFLAITATITLYLCVALGYRQPYTNLQSVTLRNFNLSQTLNSSWQLSSNLVITFQAGNPSNLPGFTTRFLHTEVNASYHTTPLGNSSIPYFSQGRHSKRNVTTEIMKTSIDELDQSSALALQAEIQSNSDVVGVRIDVNAYTKQSYLVAWTLNKWFNLTCLVDVTMPSASEPGHLVRQSCDLRISEPMLEGSVCELVPCTPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBU9</accession>
    <name>A0A8T0JBU9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G326200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="250"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="437"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="515" mass="58109" checksum="0B27719174CA180D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G645</accession>
    <name>A0A8T0G645_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Replication protein A subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_12G081700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Heterotrimer of RPA1, RPA2 and RPA3 (canonical replication protein A complex).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the replication factor A protein 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G645"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005662">
        <property type="term" value="C:DNA replication factor A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043047">
        <property type="term" value="F:single-stranded telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007140">
        <property type="term" value="P:male meiotic nuclear division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007004">
        <property type="term" value="P:telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04474">
        <property type="entry name" value="RPA1_DBD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04475">
        <property type="entry name" value="RPA1_DBD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04477">
        <property type="entry name" value="RPA1N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000041">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000064">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000090">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000117">
        <property type="entry name" value="Replication protein A subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047192">
        <property type="entry name" value="Euk_RPA1_DBD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007199">
        <property type="entry name" value="Rep_factor-A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031657">
        <property type="entry name" value="REPA_OB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004591">
        <property type="entry name" value="Rfa1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00617">
        <property type="entry name" value="rpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23273">
        <property type="entry name" value="REPLICATION FACTOR A 1, RFA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23273:SF4">
        <property type="entry name" value="REPLICATION PROTEIN A OB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04057">
        <property type="entry name" value="Rep-A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16900">
        <property type="entry name" value="REPA_OB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="786"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="15">
        <location>
            <begin position="864"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="110"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="217"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0554315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="920" mass="95759" checksum="CDBFB534E4006BD8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G659</accession>
    <name>A0A8T0G659_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rab-GAP TBC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G049400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G659"/>
    <dbReference type="OrthoDB" id="10263206at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.80:FF:000009">
        <property type="entry name" value="TBC1 domain family member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.270:FF:000024">
        <property type="entry name" value="TBC1 domain family member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.270">
        <property type="entry name" value="putative rabgap domain of human tbc1 domain family member 14 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.80">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000195">
        <property type="entry name" value="Rab-GAP-TBC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035969">
        <property type="entry name" value="Rab-GAP_TBC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957:SF27">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22957">
        <property type="entry name" value="TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00566">
        <property type="entry name" value="RabGAP-TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00164">
        <property type="entry name" value="TBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47923">
        <property type="entry name" value="Ypt/Rab-GAP domain of gyp1p"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50086">
        <property type="entry name" value="TBC_RABGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rab-GAP TBC" evidence="2">
        <location>
            <begin position="144"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="465" mass="52843" checksum="4857F6164E592954" modified="2022-10-12" version="1">MMSTGNGSNMNPKPVPAWLNSAAWASKPRSPVRASYSFGDRSSSASLVESTARPGGDLDDPLSNRAKPQETVASQEESDASALAEQAAQAQISDNSEHSSDSDENKVAKSPSSFDYRVSLFNTELSRRRIHLAELQRLSAQGIPDAGGIRATTWKVLLGFLPKNRDEWATELKKKRATYAVFREEMIINPSEVTRKKEEMEALKAAELDALEGPLQRHEISQDDHPLSLGSKSVWHQFFQDTELAEQINRDVKRTHPDMQFFCGDNDFARENQEALKRILFIFAKLNPGIRYVQGMNEVLAPLYYVFKTDVDETNANHAEEDSFFCFVELLSDFRDHFCQQLDNSAVGIRSTISQMTQLLRRHDEELWRHLEITSKVNPQFYAFRWITLLLTQEFNFADSLRLWDSLLSNPDGPLEILLRVCCAMLLCLRSRLLAGDFTTNLKLLQHYPAIDFNYLLKVADDLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G681</accession>
    <name>A0A8T0G681_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G100400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G681"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF58">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="229"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="269"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="302" mass="34582" checksum="3AD78E4BD0948E06" modified="2022-10-12" version="1">MALVVRELQCVGRCVEVNRYPVSIDRRRRGGSVRLESSLRGGGRVFLLGPSWGGGFRGEKWPKRRVAVCYAAQESLYEILGVAPTATEKELKRAYRGLALKYHPDVNKQPGAQDKFLEIKNAYQTLVDSKSRSKYDASRRTRSNDWDPFQWGSTSGSSRKSSQEEEFYGVSELWKDLQGSFDEFFRDVQADLKRRSATRREKPKSLWEELADIGEEFVEFLEKELNISDDEDGRSNSNYKSSSRSRNRDTRERSSRSKSKSNGNGNKPPRQEDSSADKAKKVENELAEIEDMLAQLKREMGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G714</accession>
    <name>A0A8T0G714_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G141500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G714"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12236" checksum="AA88EA1EB85ED651" modified="2022-10-12" version="1">MQYHFQKKNLNLNMGFTWPRRPLKLIATALPIERYNMPVISMHSSSTYAWQQGPQALGHLPCSLAPAFPEMHRIYSVHECPGLAQVQLRKAAQVMLRSSRREYLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G756</accession>
    <name>A0A8T0G756_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Uroporphyrinogen decarboxylase</fullName>
            <ecNumber evidence="6 12">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_12G125800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>uroporphyrinogen III + 4 H(+) = coproporphyrinogen III + 4 CO2</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="6 12"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G756"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.210:FF:000006">
        <property type="entry name" value="Uroporphyrinogen decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091">
        <property type="entry name" value="METHYLTETRAHYDROFOLATE:HOMOCYSTEINE METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21091:SF169">
        <property type="entry name" value="UROPORPHYRINOGEN DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="UROD/MetE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00907">
        <property type="entry name" value="UROD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="7 12" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="10 12" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="14">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Uroporphyrinogen decarboxylase (URO-D)" evidence="15">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0554860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="411" mass="44385" checksum="88B37D7A1F06CBC7" modified="2022-10-12" version="1">MACSTAALTAATSSAAVLGSNRSLKLSSVGAGSSWSSVKLVGVKSRAKCVAQAVAAETKESAANVDTSADPLLLRAVRGEEVDRPPVWIMRQAGRYMKVYQDLCEKHPTFRERSENVDLAVEVSLQPWRAFKPDGVILFSDILTPFTGMNIPFDILKTKGPIIHNPIRTAADVAQVRELVPAEAVPYVGQALTALRSEVGNASAVLGFVGAPFTLASYIVEGGSSKHFTIIKRMAFESPEILHSLLQKLAESIIIYVRYQADCGAQAVQIFDSWATHLSPVDFEVFSLPYIKQIVSAVKSTHPDLPLILYASGSGGLLERMASTGVDVVSVDWTVDMAEARQRIGTQLAVQGNMDPAALFGSKEFITNRIHDTVAKAGRHKHILNLGHGVLVGTPEENVAHFFEISKSVRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7I6</accession>
    <name>A0A8T0G7I6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G091700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7I6"/>
    <dbReference type="OrthoDB" id="550424at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10747">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000002">
        <property type="entry name" value="Dnaj homolog subfamily b member"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.20:FF:000006">
        <property type="entry name" value="DnaJ subfamily B member 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.20">
        <property type="entry name" value="Urease metallochaperone UreE, N-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051339">
        <property type="entry name" value="DnaJ_subfamily_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078:SF553">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24078">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="HSP40/DnaJ peptide-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="11"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="38980" checksum="264B2790ACA67169" modified="2022-10-12" version="1">MDKKKKDKDKDYYGVLKVGKHCTMDDLKKSYKRLAMKWHPFKNPLNPEKAMKKFRRINEAYEVLGDTHKRAIFDNYGESGLKGPVPEVGTGTQGFSMGGNTNMFKFVPRSAEEVFVEFWGGTSPFAGMAGNLNPRGHKCFRPIVPKPPPKNTCAVVVPIEVPKKPAPIVNQLQCTLEELTLGCIKKIKVARTTLDEEGQHIPTEDVLTIDVKPGWKKGTKITFPEKGNQQPGQIPADLVFLIDEKPHPTFVRDGDDLISIQKINLSDALVGLTVTLTAPDYRILNIPCYGMIRPGFEKTIKKEGMPIYREPGKKGNLILRFEIKFPIKNLTNDQKTAVKKCLPESIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G836</accession>
    <name>A0A8T0G836_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G105300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G836"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11606" checksum="6114A3DC026208F4" modified="2022-10-12" version="1">MAAQKKIYDPRQNGPPRNQPPSFELPNRKIEVEVQLGKHINSVLPCLQNDLQQHNMDNVSPDPAKNRVTVSGYPPVNGFDEHTVLAIVKRRDPQATLLASRFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA22</accession>
    <name>A0A8T0GA22_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G121800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="212" mass="23404" checksum="00615CE5839EF1F5" modified="2022-10-12" version="1">MEAATHMAGSLPGLLHTTRIYSYSQCMPGSRDCAAQRPSRVHLQCARGNRPLASSRTSRVRCQASTAVHFTDNFDSTQQEQWQVSRKLVEDLGFSPEEANDILAKSFGWSYSDYWGEEKQATVPEPETVSASLTVMKDIPGVDLSALVKKFPEVMGLTEKEIKYSLGTLDGTWGIAGKALKNVLMRNPQVLGYNIDCGGDCAGECTRCWVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBF5</accession>
    <name>A0A8T0GBF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Laccase</fullName>
            <ecNumber evidence="4 12">1.10.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Benzenediol:oxygen oxidoreductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Diphenol oxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Urishiol oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_11G004700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Lignin degradation and detoxification of lignin-derived products.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>4 hydroquinone + O2 = 4 benzosemiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11276"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17594"/>
            <dbReference type="ChEBI" id="CHEBI:17977"/>
            <dbReference type="EC" id="1.10.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="12">Binds 4 Cu cations per monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 12">Secreted</location>
            <location evidence="2 12">Extracellular space</location>
            <location evidence="2 12">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.2" evidence="4 12"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052716">
        <property type="term" value="F:hydroquinone:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046274">
        <property type="term" value="P:lignin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13849">
        <property type="entry name" value="CuRO_1_LCC_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13875">
        <property type="entry name" value="CuRO_2_LCC_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034288">
        <property type="entry name" value="CuRO_1_LCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034285">
        <property type="entry name" value="CuRO_2_LCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017761">
        <property type="entry name" value="Laccase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03389">
        <property type="entry name" value="laccase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF417">
        <property type="entry name" value="LACCASE-17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0052">Apoplast</keyword>
    <keyword evidence="10 12" id="KW-0186">Copper</keyword>
    <keyword evidence="11 12" id="KW-0439">Lignin degradation</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036511309" description="Laccase" evidence="12">
        <location>
            <begin position="29"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="15">
        <location>
            <begin position="38"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="13">
        <location>
            <begin position="165"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="14">
        <location>
            <begin position="427"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU361119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0555807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="572" mass="63259" checksum="D5007ED90465D7D8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBH7</accession>
    <name>A0A8T0GBH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G051300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="6024" checksum="4583EA2B7744D570" modified="2022-10-12" version="1">MGWEFQLKRRGRLLVSVYSLLYLDLSDPNSLCLRWKYGGQTLECFPNVPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBJ3</accession>
    <name>A0A8T0GBJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G061300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="12160" checksum="76FAA30CF55E2907" modified="2022-10-12" version="1">MWEDWVLRALVLFSVVVTSVGVIQRLVFGWQCCVSLSRGWLGLAWLFRLPRSCIGFRQLQSWPFLFFQWRSRGFCLLIAWFREWGSWIWSLSGMLKWRLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC09</accession>
    <name>A0A8T0GC09_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G038800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7520" checksum="ECFDCA755D69CE7C" modified="2022-10-12" version="1">MRVWGVAWFVGALGDRGRGCNGGDLVLLRLRLWSLELGGVFCQLFGSVWSLLLRVWILVVSTQLLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCT1</accession>
    <name>A0A8T0GCT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G111000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WIP C2H2-type zinc-finger protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.60:FF:003609">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043584">
        <property type="entry name" value="WIP1/2/3/4/5/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45878:SF44">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45878">
        <property type="entry name" value="ZINC FINGER PROTEIN WIP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00096">
        <property type="entry name" value="zf-C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="248"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="380"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="383"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="548" mass="59812" checksum="05D6833A41B24E8E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDP5</accession>
    <name>A0A8T0GDP5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_11G035800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Na(+)(in) + H(+)(out) = Na(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDP5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF86">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="213"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="407"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="14">
        <location>
            <begin position="733"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1003"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1126"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1003"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0556219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1160" mass="129453" checksum="27BD3487C084E0FE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGJ3</accession>
    <name>A0A8T0GGJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G007300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="9592" checksum="C34C65A2107E9C5F" modified="2022-10-12" version="1">MARLTMAKSLMGMVAVGCMTSLPSQRSVTTRIHTNNNPANNHAAHSGSGSQMRDIAKEPLPDSERSSVIAMDHEVGQRHGCHGSHRESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHP9</accession>
    <name>A0A8T0GHP9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxynucleoside kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G061600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050566">
        <property type="entry name" value="Deoxyribonucleoside_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10513:SF47">
        <property type="entry name" value="DEOXYNUCLEOSIDE KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Deoxynucleoside kinase" evidence="1">
        <location>
            <begin position="108"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="361" mass="40729" checksum="5BE8C8700E3E8C0D" modified="2022-10-12" version="1">MEALARKFPASWFSSLNLMAVPLKRYMETASSKTQLPSGEPQLLSAPVADAQTQVHDEAAFQQPEDEVDTIEQYLEHFPTKKTRAGIIDREGNESENFLLKASKPARISFEGNIGVGKSTILKLLHSHPRLKQVTEILQEPIWEWQNVKGTGLNMLEAFYKNPQRYAYLFQSFVFTTRFLQQNAAASQSKAALLLMERSVLTDRCVFVKTAREQGYFNTLEVAAYDAWYNGVITTLPNVVPDAFVYLRADPNVCYERLKARARSEEAEVSLEYLQSLHSKHEKWFIESAFDDAGNWGGKSQAGHFSSSSKVPAVIRGRPIFVVDCSKTLEFDKPSKEVDRVIEEIVGFLLAPPSESLCKFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKD4</accession>
    <name>A0A8T0GKD4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G071100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKD4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0558997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="25761" checksum="5A76CADA9D384199" modified="2022-10-12" version="1" fragment="single">TIHCYDHFYSNFFPICSISFLRLVFGLTRHGTRRLVKSCEGSGIKCRIRVRVRVRVSSGAFLVWRPRQGRSSFAISLALASSLAGVAVANTATMVKFLKPNKVVVLLQGRYAGRKAVIVKNFDDGTKERPYGHAIVTGIAKYPRKVIKKASQKTIAKRSRLKAFTKVVNYNHIMPTRYTLDVDLKSTVTAEKLESTASRVEARKGAKAVLEERFKTGKNRWFFSKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKX5</accession>
    <name>A0A8T0GKX5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G121500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="240"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="448" mass="49022" checksum="9005CB2200018C4F" modified="2022-10-12" version="1">MISNGTGDGVGPTSSHYASISNPSQMICVELNHELGHDSDENYWRKQLNINPFSPPRQCDGLAFLNWHSIGESSESMSLRSSDAANCVDRHPIQQPAPRSNGDPQGIDGNHGAAMTSNLDHAPLVSSIPDITAPGHFSAAEPLCQPLNGKACPEKLSMVELSARKDKSFTFHESYDEGSSKGKQPQHNGKDHEVARSGRPGPGILHTVRKTCAKPPRRTPRKSAPTGGKKQCVQIDADKTARIRKINWTLMETAILLFIKLFFLMTPGESWSERASEFLISKGFDRTPSECQQRWDTMKKNYDKPSRIDEGNVPAGFLGGQSLLYDLMRMIMGGHVEQQGPSRDTQSSEQLEGALAQSSAIHTDTIEFSNADGPSLPPDVPTFLSDDAYDSGQKTNSSSYASLYASVGRLWQEVGRLSQDVKTMKDRDAEILVGSYLDLTNDGSFPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP84</accession>
    <name>A0A8T0GP84_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Uridine kinase</fullName>
            <ecNumber evidence="10">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_10G178100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the UPRTase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="10"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP84"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000015">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000339">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="12">
        <location>
            <begin position="79"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="13">
        <location>
            <begin position="295"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0560397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="57636" checksum="5E853BADD4E191A6" modified="2022-10-12" version="1">MRDLNGDGDRRMPQASPDMISDTWDLTPDRYNPIVSDKESKPEKLDPAMEPTADGHFTGLHFDEYPVTKHLGANKVPFVIGVAGGTASGKTTVCDMIIQQLHDHRVVLVNQDSFYRGLTPEESAKVGEYNFDHPDAFDSEALLECLEQLKANQPIKIPEYDFKSHQRCSEKFRKVNASDVIIVEGILIFHDARLREYMNMKIFVDTDADVRLARRIRRDTLERGRDVNGVIEQYGRFVKPAFDDFVLPTKKYADVILPRGGDNHVAIDLIVQHIRTKLGQHDLRKIYPNVFVIQSTFQVRGMHTLIRDQQTTKHDFVFYSDRLIRLIVEHGLGHLPFTEKQVITPTGSIYVGVDFCKQLCGVSIIRSGESMENALRACCKGIKIGKILIHREGDNGKQLIYEKLPYDIADRHVLLMDPILGTGNSAIQAILLLIQKGVPESHIIFLNLISAPEGIHAVCKKFPLLKIVTSEIDAGLNSEYRVVPGMGEFGDRYFGTDDDGPELLHKVPIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPN1</accession>
    <name>A0A8T0GPN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G073100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035840125" evidence="1">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6458" checksum="04D5AEF30DD5DE41" modified="2022-10-12" version="1">MLVPFLQLGFSFHHASSLWMCVSSATYRVVEQKTSKVIYEVHKIILLESRNGLGFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ52</accession>
    <name>A0A8T0GQ52_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G007300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ52"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="407" mass="44878" checksum="1D43966CFA13A303" modified="2022-10-12" version="1">MDFNSNEEYVKAFPPNFSPKIERPHKEQLFDLNAHGLPPKENQENVETKPAEVPEPLCLDDELECVEVQEPIQVGAVKADDHVGDVLLEEQEEILILGDDLAPEIDEPMPQMADMALLREEEMVVDDGDGGTLETMLSMEAIEGSALDNEPLGEVEAVMEDEIFEECNPKEFITSTGDFTELERPFTDVADKVEGNAMETEAQQPAIEIQVIESTVITAETPDQIEFVESAIRALEEASENADAVGHIQIKEPVTLEVTEKTTIRTTPLTETKEKADLDAGTEETTTALEIVEKTTIKAKAICQDEEEDPRFTVKFTESTSTTITGFDEELDPCSEADVDRIVDSIMNDIAGIEANMKKEGEDAGLEANIESNRQHQKVTLTYEKPSGIEGEDLTCQDHVGPSKGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRI0</accession>
    <name>A0A8T0GRI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted peptide</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G044300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035801061" description="Secreted peptide" evidence="1">
        <location>
            <begin position="20"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8175" checksum="294379AC15E2DA7D" modified="2022-10-12" version="1">MVFVLFSLWTFLLRIPVCAYGGGIWSSVLSYCLATVFCMSTIMIAYRCKLSVPGRNSIHRNRIVFSLSFCNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSR9</accession>
    <name>A0A8T0GSR9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G176900</name>
        <name evidence="1" type="ORF">KC19_9G111700</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSR9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="44" mass="4862" checksum="37FE40E63975DD74" modified="2022-10-12" version="1">MERYGFGSCGEVEASSRLGSSEFTTFRETGQLIVERTVVCVTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSX9</accession>
    <name>A0A8T0GSX9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G011800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13447" checksum="6A2CF82DA82DEA8E" modified="2022-10-12" version="1">MRYLETAFNLAEIRIQDMLISGCWYKVDGTLVTLEHVHIGEVKTVQLEPKQQAAVDVLNESSGLIARTFRFSKSLSGNEKPHSGEACRDLFMASMDTLDSGEVFFALKQPQFSNGIQYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTC3</accession>
    <name>A0A8T0GTC3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G183500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="387" mass="44565" checksum="4BA0699B8E7D1865" modified="2022-10-12" version="1">MDMSAALWSDLPLEMLEQVLSYLPVPDLYRYRTVCKRWDRLMWDPKFGSLCAQNAVKREASLIVMPYGIRGMGHLGWCFLDVNARRWYVFKDDGQSNPRNFARNSPVRMDGGLVCQYDLWSDRIIVYNPMSQTHREVPTVPRKCLAPSHFEELIFVVDNISQSFKIFLFYTSHPHSLKNALKLVYDSVTNEWKTSTSPLCISSGSKLLGHRVLFEGYLYTYLYYGEHTLWRYNLVKDAWEKLDVPLGDEFTGARLLVTANRLFLVAWSKGRGLGFDDGGPSWSFQLSELKITDMTREVLFEMSEADVKERFETGIENRSTGLPGITAFSFGNSLLFMSESTGVTAAFDVVTRSWDRNFPPNPLEYLPDEDCMWDGDQMNLLLPCTVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTX2</accession>
    <name>A0A8T0GTX2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G178600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTX2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033699">
        <property type="term" value="F:DNA 5'-adenosine monophosphate hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990165">
        <property type="term" value="F:single-strand break-containing DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000012">
        <property type="term" value="P:single strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.428.10:FF:000004">
        <property type="entry name" value="aprataxin isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002337">
        <property type="entry name" value="Transcription factor bHLH140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019406">
        <property type="entry name" value="APLF_PBZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032566">
        <property type="entry name" value="Znf-C2HE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486:SF4">
        <property type="entry name" value="APRATAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12486">
        <property type="entry name" value="APRATAXIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11969">
        <property type="entry name" value="DcpS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16278">
        <property type="entry name" value="zf-C2HE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10283">
        <property type="entry name" value="zf-CCHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="2">
        <location>
            <begin position="339"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="535"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="796" mass="87520" checksum="99DF44CB4BD63EB9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWM6</accession>
    <name>A0A8T0GWM6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G154100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="199" mass="22592" checksum="D822ECD0985FC08A" modified="2022-10-12" version="1">MYVYQCLCTWPAMCMSVFPFTLNPPTPCRCAVIVLCTSFCDMNSLRDSSNPWNLNHSTTKHHQSYPPYTEVQFTPQYTVQLYYRTTQRIPNLHHSNARTRHKSHGHRDIDPDLMRRCRSLFARQHDDTARQCPIAVKHISTSPIFTENLGLGVNGIPRPVTSLAETLVSIHASTPVIHVCSTSEGKANSQRRGSFCSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H019</accession>
    <name>A0A8T0H019_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methenyltetrahydrofolate synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G190700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H019"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10420:FF:000004">
        <property type="entry name" value="5-formyltetrahydrofolate cyclo-ligase-like protein COG0212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13017">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13017:SF0">
        <property type="entry name" value="METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="382"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="351"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="473" mass="51174" checksum="BF273D47AF3EDBB0" modified="2022-10-12" version="1">MAMVSLLAGRLPLQSSGKLALSAFTPSPAMADACSCKFTGLSMKRRSLVSSCVQASTQEGSAAVAGVESEEQRLELDAEARSAMAAVAEAQAGRDGQGAAPGAWKWAIRKRVWDLLESENLAQLPRPVHHRIPNFVGAGAAAMKLASLPAFETARCVKVNPDTPQKQVRFLTLNGNKILMTPQPRLRTGFFSILESSSIPYLPDACTSAGVAKFGKPISLDDKLKVDLIVIGSVAVDPKTGARLGKGEGFAELEYGILRWMGAIDDSTLVVTTVHDQQLVDDIPLEKLLIHDVPVDIICTPTQIIHTNTKIPKPKGIYWEKLSRQKLGQIRVLQDLKKRIEKETGKTLPCAPDEVLPPLAVRQRPPPKGSGRTRNSVTAHKQTIFMWNLSPSTTKRELEDHVAQLGGDFFLTVRTSLKPGNNRQLAWVTLKDGADAGKIVKALDQSTLGEMVVRAKVDEPTSAGKSHSQPQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0E9</accession>
    <name>A0A8T0H0E9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Origin recognition complex subunit 3 winged helix C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G140500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0E9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031261">
        <property type="term" value="C:DNA replication preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005656">
        <property type="term" value="C:nuclear pre-replicative complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020795">
        <property type="entry name" value="ORC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040855">
        <property type="entry name" value="ORC_WH_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12748:SF0">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18137">
        <property type="entry name" value="WHD_ORC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Origin recognition complex subunit 3 winged helix C-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8315" checksum="C1F591E20FBE3F4E" modified="2022-10-12" version="1">MSSINVHDWYQSLSSICCPVKVSSAKKGKGGKSEGTAGDPVIIQARFTRAATELQIAGLLRMPKKGRPDFAHRVCLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0S9</accession>
    <name>A0A8T0H0S9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G048900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0S9"/>
    <dbReference type="OrthoDB" id="1372046at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11043">
        <property type="entry name" value="CYP90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000022">
        <property type="entry name" value="Taxadiene 5-alpha hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286">
        <property type="entry name" value="CYTOCHROME P450 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24286:SF384">
        <property type="entry name" value="P450, PUTATIVE (EUROFUNG)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0563658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="507" mass="57104" checksum="0A8B399B84F60023" modified="2022-10-12" version="1">MKMEGIIGQVEQLAGKTEWAAVGVALVAVVVGLVLWKCSSGLKRVTPPVPPGSLGWPVLGETLELLSAKRANIADQFYKARVAKYGEVFKTHLFLDPVVSVGGADGNKFLFSNENKLVQNSWPPSMIKILGKDTIINQVGERHRKLRRIFTSNFFNPEGIALYVSRMDAITRDHIAKHWEGKDSILGVPTVREFTYSVAADIFMSLRETDPRYRALSQTMEDVIQGVLQVPINLPGTVYHKGWVGRGNMNAILDTLISERKQELEQGKASSKKDLLTMMLTTPNEDGIMLNDDQMKDNVNNMLFAGHETSSSTMAVALKYLYLNPECLKKVLQEQREIAKDKNGAPLDYSDTRKMKYTWQVVQETLRLQPPVQQAFRTALQNFQYAGYTILKGWKVSWASDRSHLDPKYFPNPEKFDPSRFEGSGPPPYVYIPFGGGPHICLGNEFARTVIMVFLHHIVLNFEWKLVDPDETICIDPLPIFSKSLALQIQKRPQVPNSYGRHLLIDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1M8</accession>
    <name>A0A8T0H1M8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Geranylgeranyl transferase type II subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Type II protein geranyl-geranyltransferase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G099200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1M8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005968">
        <property type="term" value="C:Rab-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004663">
        <property type="term" value="F:Rab geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045089">
        <property type="entry name" value="PGGT1B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001330">
        <property type="entry name" value="Prenyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11774:SF11">
        <property type="entry name" value="GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00432">
        <property type="entry name" value="Prenyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="Terpenoid cyclases/Protein prenyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prenyltransferase alpha-alpha toroid" evidence="10">
        <location>
            <begin position="27"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0564289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16434" checksum="6E625BE1A7421EE4" modified="2022-10-12" version="1">MGFTTRNATKTTVEIFAPGNKVKSDFDAVAMEHLRMSGAYWGLTALDIMGRLGDMNADEIVAWILKCQDECGGFGGNYQHYPHILYTLSAVQILCLFDRLDAVDGDKIARRLMRCWYDRLHGQEFSLHQLGSQLICLSRHLTTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1N6</accession>
    <name>A0A8T0H1N6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G159600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1N6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13597" checksum="3259D045A14A98CA" modified="2022-10-12" version="1">MYKPTFCIYNVIVTPCFCVYHPWCVSMHTWIYNHCANSNCQEKFPDSWLKSFGLHGIEEPYKGSVKTESSVKKQFYLNLDIGGLNYIPKRKFAMTNYLVQLLKSPLYVLLRMTLDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1N8</accession>
    <name>A0A8T0H1N8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G073900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1N8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05282">
        <property type="entry name" value="ETR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106">
        <property type="entry name" value="QUINONE OXIDOREDUCTASE PIG3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48106:SF2">
        <property type="entry name" value="ZN2+-BINDING DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="3">
        <location>
            <begin position="92"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="409" mass="44025" checksum="A61369420B48F2FB" modified="2022-10-12" version="1">MSSRLSYLSSLSYTLAVIHCNAMFSSHASSVTHRRLKRAFLFPCIQGLQSADVNLGTAIAAAGNRSDAGTYCPYTRNMSNVAIVQDGFNQDDPLSTLKVVNKPIPKPAPGQVVVQIKLRPINPTDFITLRLGGIAQGGICGSEGFGIVHEIGEGVKSVHKGQRVIPFTAYPSLSGHGSYQKYVCLEEDFVWPVPDYISDEVAALFVVNPWASYSIVKDLQVPKGEYLLQSAAGSSLGKQVITLAKHWGIKTINIVRRKEAVAELKALGADEVIVSTEEDVVARVKEITGGKGAYGALDAICGTMTKTIAASVRDDGQVFLYGVLAGYDATVSAIDLVFRRVDVKGWVLYTKAMNQSDRCQAIAPEVAPLLRDGIIPVPKTVKYDLTDFKKAMAKAEEPGFAGKVLLVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1Q6</accession>
    <name>A0A8T0H1Q6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glutamate--cysteine ligase</fullName>
            <ecNumber evidence="13">6.3.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G133600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-cysteine + L-glutamate + ATP = gamma-L-glutamyl-L-cysteine + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer or monomer when oxidized or reduced, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Plastid</location>
            <location evidence="1 13">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="13"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1Q6"/>
    <dbReference type="OrthoDB" id="10362117at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006750">
        <property type="term" value="P:glutathione biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035434">
        <property type="entry name" value="GCL_bact_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011556">
        <property type="entry name" value="Glut_cys_lig_pln_type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01436">
        <property type="entry name" value="glu_cys_lig_pln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34378:SF1">
        <property type="entry name" value="GLUTAMATE--CYSTEINE LIGASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017901">
        <property type="entry name" value="GCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0317">Glutathione biosynthesis</keyword>
    <keyword evidence="6 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR017901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0564717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="493" mass="55764" checksum="D216C736B932A535" modified="2022-10-12" version="1">MAGMNGATMAENAPVRTASNGEYDRFGTKVQQANGSNRTWPIKPAFRSNSMKSTEKPLTKEDLVAYLVSGCKPKANWRVGVENEKFGFQLDTLKPMTLDNIHELLEGMASHFGHKRIIEDGTIAGLQKDGQSVTLEPGGQFELSGAPLEDIHAVKRELDIHLEEVNTIGKELGLGFAGMGYEPKWPIPERPYYNKAGRFDIVHDYVRDIGAPESLKVMHQTCTGQVNLDFDSEQDMINKLRVGLSFQPIATALFATSPFSEGKPTGYLSYRSITWTEFDDKRTGVLPFVFDDDFGFEKYAEYALNVPMLMIYRNQHWHYTKGASFKDFMAGKLQGFEGERPSIEDWMNHLGNLYPEVRLKKYLEMRGADCGPRPFLLALPAFWVGLLYDEQSLQGALEIIRDWTNDEREMLRNEAPRLGLQVPFRGGLLKDVAQDIVKLAKEGLIRRGLNEEGYLAPIEEVASSGVTLAERLLKLYYDKWDKKVDPIFDELRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H294</accession>
    <name>A0A8T0H294_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G014200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H294"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="11386" checksum="7ED3DAE523E411CE" modified="2022-10-12" version="1">MEILNYSHNFKPQETKTFYAIHGKYVISLLINYICINQHVVKMSYLSFKITNITKNMTCFLIMNFFILKNIIVYWNQHILHTRWLNNDGCYNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7H1</accession>
    <name>A0A8T0H7H1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G169300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 16">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 16">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="4"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7H1"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.40.10:FF:000010">
        <property type="entry name" value="Probable protein phosphatase 2C 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="13">
        <location>
            <begin position="68"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0567886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="34580" checksum="3477514291255060" modified="2022-10-12" version="1">MRQSVSERERANAETKTGMPREDDHVEEAGTVRVNIASHQAVTRGDGAASTTSLREASYGGGESQRLVWGYCLLQGLAGRVMEDLHVAEVRSVNGEEVAFFAVFDSHNGDDVAKYLQKNLFENILNEGGVWSDPTGATRDAYLRTDRDILDSDVEKGGSTAVTAMVCGNGSHVIVANLGDSRAVLCKNGKAVQFSVDHDPGRPTERAIVEARGGHVTHLPGDQWRVDGQLALARAFGDKGLKEHMSAKPDVSDIVIDSSCDFLVLGSNGLFSMFDNQEVVDRVKGSDDPVKAAHHLVLEARRRLSEDDISCIVIMFQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9B7</accession>
    <name>A0A8T0H9B7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G005200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9B7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11453">
        <property type="entry name" value="bHLH_AtBIM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044295">
        <property type="entry name" value="BIM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46412">
        <property type="entry name" value="BES1-INTERACTING MYC-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46412:SF3">
        <property type="entry name" value="TRANSCRIPTION FACTOR BIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="4">
        <location>
            <begin position="327"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="265"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="450"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="527"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="720"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="456"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="615"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="721"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="754"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="763" mass="82592" checksum="A93968BD538F404D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAN6</accession>
    <name>A0A8T0HAN6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G048100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAN6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11372" checksum="025DA42B4C9AB605" modified="2022-10-12" version="1">MWPSSKTQSTTAGESLHQNPNLNSQKPTLQLTPIPNLTDHNPTLSKNARPKHNQSSPAPKPFAQFSPSPSHNPPQSTQRLDLTTLTAISNITQPKHNSIPLLQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAX0</accession>
    <name>A0A8T0HAX0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G139100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005684">
        <property type="term" value="C:U2-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034247">
        <property type="term" value="P:snoRNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16539">
        <property type="entry name" value="RING-HC_RNF113A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000045">
        <property type="entry name" value="RING finger protein 113A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000014">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039971">
        <property type="entry name" value="CWC24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930:SF0">
        <property type="entry name" value="RING FINGER PROTEIN 113B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12930">
        <property type="entry name" value="ZINC FINGER PROTEIN 183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="7">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="299"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="4">
        <location>
            <begin position="223"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0567494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="366" mass="40540" checksum="854664A870C2B894" modified="2022-10-12" version="1">MAESSSKFCIQGDNLVSRIFARAIPAMAGDTEPLEAGVEPVAPVDPPAGTFFKKIRNKSNMRKRTQDEAEEDEGSGQASAVASKAKLAKKADGRLGFSSGGPKLDTAVAESVPVVDELKRNAFFYESTRQVQTLDDSRATAVSEIETAFDRDNRAIRERVLKQASEALKSGETSGSKVYKGIHGYTDHKAGFRQEHTISREKAGGAHGPLRASAHIRMTVRFDYQPDICKDYKETGYCGYGDSCKFMHDRGDYKSGWQMEREWDQEEKERKARLARGEAETEEGAGDDSDDEDEIPFACFICREPFTDPVVTQCKHYFCEHCALKHHSRNKLCFVCNKATNGVFNTAHEIVRKQKEAKAAAEAAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBN7</accession>
    <name>A0A8T0HBN7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RIC1 C-terminal alpha solenoid region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G038300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBN7"/>
    <dbReference type="OrthoDB" id="67540at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034066">
        <property type="term" value="C:Ric1-Rgp1 guanyl-nucleotide exchange factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040096">
        <property type="entry name" value="Ric1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009771">
        <property type="entry name" value="RIC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746:SF10">
        <property type="entry name" value="GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22746">
        <property type="entry name" value="RAB6A-GEF COMPLEX PARTNER PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25440">
        <property type="entry name" value="Beta-prop_RIC1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07064">
        <property type="entry name" value="RIC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69322">
        <property type="entry name" value="Tricorn protease domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RIC1 C-terminal alpha solenoid region" evidence="3">
        <location>
            <begin position="788"/>
            <end position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1139" mass="127344" checksum="A50E7925C2D5C75A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCH1</accession>
    <name>A0A8T0HCH1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G033500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16983" checksum="D18FBF6E680BB844" modified="2022-10-12" version="1">MEVHSLHSSNIPPLMLLNRHYCNYIKPYANLITKDCDPRDQKSQRLIKFGPVLKIVFHLTQFQHTKHKLHPHTHQRPPSSYYRNSINLLQIKRLTLDSKESSTNALELIQRLKEEFFGAQSASLDAEGVLAAGAATGLAKARVSVASPWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCL7</accession>
    <name>A0A8T0HCL7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G075700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035762652" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9525" checksum="F8EF60C9D20AC67F" modified="2022-10-12" version="1">MTRKHERRCLLLLISNLTTTVEQFGAQENGNRGSFREDQNQLLCMNSSSTRRRYTSSNFTMPKMITNTSSSVDTETKTPASLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE10</accession>
    <name>A0A8T0HE10_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G015900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6289" checksum="EAF9D205C4743CEB" modified="2022-10-12" version="1">MMILFTFWGNIITTIIQMLHAVFVGNHCKRLNEYKGVKSVIITMHQVFQDCDMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF24</accession>
    <name>A0A8T0HF24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G157200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF24"/>
    <dbReference type="OrthoDB" id="2012870at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33644:SF2">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33644">
        <property type="entry name" value="U-BOX DOMAIN-CONTAINING PROTEIN 62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="611" mass="66763" checksum="9510DD97DFF4416A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFS3</accession>
    <name>A0A8T0HFS3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dirigent protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G165100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Secreted</location>
            <location evidence="4">Extracellular space</location>
            <location evidence="4">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the plant dirigent protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFS3"/>
    <dbReference type="OrthoDB" id="1928589at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009699">
        <property type="term" value="P:phenylpropanoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.480.10">
        <property type="entry name" value="Allene oxide cyclase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044859">
        <property type="entry name" value="Allene_oxi_cyc_Dirigent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004265">
        <property type="entry name" value="Dirigent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21495">
        <property type="entry name" value="NUCLEOPORIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03018">
        <property type="entry name" value="Dirigent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0052">Apoplast</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035958415" description="Dirigent protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0570473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="20272" checksum="C413DFD8C4B0B8DD" modified="2022-10-12" version="1">MAKLAGATWHFVVMLGLILCLGACNGVSARLNPRHKTHNVTFYVQEAINTGDDATAFIVGGPDGNTSALQLGAVIVVDNAIFATADPKSKQLGKFQGLYVVDGGHKYRAEITVTIDQPGDLIECTYEILGQRPSFNTTSDRQLAVVGGTGLFLGQKGYAIAHTVSQTLLHEGTLPDAQYNVQKWTLVVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG48</accession>
    <name>A0A8T0HG48_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G174400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12423" checksum="6B582122B1182C02" modified="2022-10-12" version="1">MSTNAMIFADWVVLLYKEKVDPMARSPIHTHVQVCAHTHMTRNVDPTFPRILKNPSNIFNQGVALGRTEMGLIILDFAEHCIWYGHILDTVCKTSFLVMLSLRSKVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGE5</accession>
    <name>A0A8T0HGE5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G109900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGE5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="82" mass="9306" checksum="76F68A87AEB76499" modified="2022-10-12" version="1" fragment="single">HSESRFLAAPRCSVHLFSSSCAWLCRSQCRSYFYLVLLEWGAIAFHFVTEAACCSYDAAKLFFFDFPSARKQNGPRLNGNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGY2</accession>
    <name>A0A8T0HGY2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G155300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGY2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051:SF0">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23051">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35, MEMBER F5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="41708" checksum="376C15E461D50993" modified="2022-10-12" version="1">MEKTWRWMLGMLYVVLVAVIWIIASFVVQSVVDAGVSPFLISYICNSLFVVYLPIVEGGNLVRRWLAGGLEGRSGAEKETVRLLEEPLGGGESSGGNPNSVVEADGGLDSNREVVNRVWSRREIAQVSLLICPFWFLAQFTFNLSLRYTSVTSNTILSSASSLFTFLFSLALLNEKFKWTKLLSVFLCMIGTIIVTLADSTGSEGVYKKAWWGDILCLFSALVYALYSTLLRKRLPDEEAGEGKASTALFFGYLGLFNAILLGPVALILHFTGLETFRRLTLSQVGLIVGKGLLDNVLSDYLWAKAVLLTTPTAATTGLTIQVPIAGVVDSLRGNIPSPLNILGAVAILLGFFGINEPATGCFGSSTEDVDDFDNVKESADVSTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIM3</accession>
    <name>A0A8T0HIM3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phytol kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G099500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the polyprenol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIM3"/>
    <dbReference type="OrthoDB" id="5673at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523:SF7">
        <property type="entry name" value="FARNESOL KINASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PHYTOL KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="188"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="288"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="362" mass="38328" checksum="728C77317FE8DE6C" modified="2022-10-12" version="1">MALSMHCSLMGRGFAVTNPFSVGQKVRSKDLRRRCGVGGDRELGGRAERFKAWCGVAEGGEGGGRVDVQGFRMAGFVESWRLSSGGGGCGGSLSSGGLWRRFSAALLCSCAVVTPGMASPVGAVESVAVSDYVAALVTLAGALGILQFFDELAKRELLEKKLSRKLCHILSGLVFMLFWPFFSSAPLAKYMAAFAPFANGVRMIGLGLGFWRNEALVKAISREGGQRELLHGPLYYAITITIATLCFWRNSPVGACAVATLCAGDGFADIVGRKYGTRKLPYNSSKSIIGSVAFFVFASLACMGYVAYFSAFGFFTATAQMYLATMGVALASAIAESLPLPVDDNFTVPFTAIGAGMLLLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIY3</accession>
    <name>A0A8T0HIY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G154100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the thioredoxin family. Plant H-type subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016671">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000104">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050620">
        <property type="entry name" value="Thioredoxin_H-type-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10438:SF463">
        <property type="entry name" value="THIOREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin" evidence="6">
        <location>
            <begin position="24"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="15382" checksum="C67BEC878A0907DA" modified="2022-10-12" version="1">MMESFISWLNGVASGPSEMAGDESKAASKIHIISNAAAWDSKLEEAKSSGKIVVVDFTATWCGPCRLMAPVFAAASMKFDNLMFLKVDVDEVQDVTSQYEVRAMPTFLFIKDGKQVDKIVGANKDELEKKCNHWASVVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ19</accession>
    <name>A0A8T0HJ19_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G180200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ19"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044575">
        <property type="entry name" value="RAY1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47483">
        <property type="entry name" value="BETA-ARABINOFURANOSYLTRANSFERASE RAY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47483:SF1">
        <property type="entry name" value="BETA-ARABINOFURANOSYLTRANSFERASE RAY1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="1">
        <location>
            <begin position="462"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="704" mass="79221" checksum="769F1E34304CAB23" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM65</accession>
    <name>A0A8T0HM65_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG051100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM65"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="11903" checksum="35704958B1B3A9B4" modified="2022-10-12" version="1">MSSPALRLLMTFCRRSSKMSSSGTANEDVDGVSERRITGSGAFVVRPEIMSSGSGTVLTGGSSNTSSIWSCIGDGGVYLLMLTGDHSPPFFLVSFSSPQFLPWQSQTVIQSSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR13</accession>
    <name>A0A8T0HR13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RRM Nup35-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_VG171900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nup35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044613">
        <property type="term" value="C:nuclear pore central transport channel"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044615">
        <property type="term" value="C:nuclear pore nuclear basket"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005543">
        <property type="term" value="F:phospholipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006607">
        <property type="term" value="P:NLS-bearing protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006999">
        <property type="term" value="P:nuclear pore organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12441">
        <property type="entry name" value="RRM_Nup53_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000095">
        <property type="entry name" value="Putative Nucleoporin NUP53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007846">
        <property type="entry name" value="RRM_NUP35_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21527">
        <property type="entry name" value="NUCLEOPORIN NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21527:SF6">
        <property type="entry name" value="NUCLEOPORIN NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05172">
        <property type="entry name" value="RRM_Nup35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51472">
        <property type="entry name" value="RRM_NUP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7 9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RRM Nup35-type" evidence="11">
        <location>
            <begin position="260"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="35"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="125"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0573364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="46936" checksum="EACB98E3AE86631D" modified="2022-10-12" version="1">MSVNESVKRLEWECVGGVLILEFFHERGRGGTGLRVWRPSRPTAGFNQGAMNTPGMQPRSASRGGRSQSLFYRDLSASPVTRAPSSRRELGTPGQAAAAAALWRENTGGFNPPPPPMFTLEDRVERSVDDTSGADQTYRNPDSAKYTDGRSSNRTPLSNGQVGYNYSYSDPIMEPSTLSASPRTPSQNQSASSPIWWSGSRDRNAHEGISGRGGDNDGVSPVSGVVQPQKQQPRGLLALEPPRDVVRPEVQRSGGAPDVVEGDEWVTVFGFGAEETNTVMRELEKCGPLVDYVSGPGGANWVHIQYQNRLDAKKALLKDGMMLNGSLIVGVKSLDPSQRQVLTDRRKQPASMTMARRTTGWGAANTSGQASQRPYYVQRTENGPRSAGVLATPAKSTVSKFVDFVFGWSHIAARHGRLSKHCYERLRDDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS57</accession>
    <name>A0A8T0HS57_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG192300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="397" mass="44507" checksum="D2EB407C107335A6" modified="2022-10-12" version="1">MATGRQAELIRKGIQDVDSTRRRRGRTHSQIPIARAASGRLSVSQRDGGASASRGVGGASGLRRDEGVFTSRRDGGGSTSRRDGGESISRADRGRGQKEALIADAQANAAHYRAALNASEKMELEELRKEVKRLKAKLGRITRLHVLECERNRPPPRFCEIKNVEKAQRQVVNYLLLGMDPATATLFPEQSQLYKAIKAFFKIDEEEEGIEFERAYSDGSELMSKVFEYVRIRRSRILQDAKKEMWRILGCPHLPPNATDEEKAARKERLEAARRGERWRIGYGNDGHADPFGSDAVHRALAKTFYGAAYSADVAVTITLEQAGFFLHGLGLAMKDDTMHPHDTTKNREEIRKCMGIVSGFMGDMRRIEVVEHEASEQNIEGREYREISNHASNARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSL2</accession>
    <name>A0A8T0HSL2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG227600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="RIBONUCLEASE III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207:SF34">
        <property type="entry name" value="RIBONUCLEASE III DOMAIN-CONTAINING PROTEIN RNC1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNase III" evidence="3">
        <location>
            <begin position="159"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0574010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="544" mass="62345" checksum="B87C42F8544555E6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWW9</accession>
    <name>A0A8T0HWW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G017800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWW9"/>
    <dbReference type="OrthoDB" id="1858881at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33872">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33872:SF2">
        <property type="entry name" value="DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="14185" checksum="43E7808A84F327A6" modified="2022-10-12" version="1">MGSLMAGWDKNPWNEERVITRSKTSLTKEEIEEYWRKRQLSMEEHMKEASAQGVASQSETGAGTPTIDIPQIIAEELEIPVAMSPDWWTRSNSAFLNSPPEKDVLIKHSKYTAQYEVATKAKQTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYT0</accession>
    <name>A0A8T0HYT0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Centromere protein O</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G015000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
            <location evidence="2">Centromere</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CENP-O/MCM21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYT0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031511">
        <property type="term" value="C:Mis6-Sim4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd23836">
        <property type="entry name" value="DRWD-C_CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23835">
        <property type="entry name" value="DRWD-N_CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018464">
        <property type="entry name" value="CENP-O"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582:SF1">
        <property type="entry name" value="CENTROMERE PROTEIN O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14582">
        <property type="entry name" value="INNER KINETOCHORE SUBUNIT MAL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09496">
        <property type="entry name" value="CENP-O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0137">Centromere</keyword>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="387"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="60"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0575593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46144" checksum="9F7E51604E27289A" modified="2022-10-12" version="1">MGEEKEKRKVGERRSAQRIKRVLADTTPKHLEQLTKQARALAGDDGEGDGEDSSMDAVRRKLGHLHKRHASLREKLTHPSPPQKSLVLRMQEEFEKGIEGRRLEGEEWNDSVIKELQERLYSGDAAGSAQDDQEANGEPQIGDRQGGEEKMTVLVNRKVIRGVKGGHIVIRFDTAFGAKNFESYYCVLKSNSSMDKLYVVEHSIPFFLPVRELEKQHLSNSPKRFIDHMGDVLQAYVSRREQVIELKKLKGDLIGELYHSLSYTLIEIMLKEPQCQVGLSLAYHNSDSELPTQSTITAWPLSTDLITQTAAKRPGRAILKNSTAFRLPKAEAFLRTMPLPRGFEEFLGDLRDTLGLSSPQVVVAAPQVAIEAPHPATEAAKPVMEAPKPTIETQPLPNEAQPMEIEASVEAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZD8</accession>
    <name>A0A8T0HZD8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G088200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02079">
        <property type="entry name" value="P-type_ATPase_HM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22249">
        <property type="entry name" value="UDM1_RNF168_RNF169-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000022">
        <property type="entry name" value="Putative cadmium/zinc-transporting ATPase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051014">
        <property type="entry name" value="Cation_Transport_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085">
        <property type="entry name" value="CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085:SF5">
        <property type="entry name" value="CADMIUM_ZINC-TRANSPORTING ATPASE HMA4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01229">
        <property type="entry name" value="COF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="418"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="609"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="933"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="13">
        <location>
            <begin position="282"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="210"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1359"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1444"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="1398"/>
            <end position="1430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="1451"/>
            <end position="1466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="1479"/>
            <end position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0576540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1501" mass="162826" checksum="690CD5EE48312072" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I034</accession>
    <name>A0A8T0I034_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G085000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I034"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="361" mass="40115" checksum="F718DE4E21E3659D" modified="2022-10-12" version="1">MLSFLHLGNRHLSQGNSFRKMAVAMAMTMAGARPSLFEQHPFVRLLELPATTSSPPLPVLQTSRGPSFETINGVVTPDLPIKASLIEYFHSLELKHILPNLRQKSLKEEISSFDSSLDSQTSSFETLRGFNCWQVRTVAAQTRSLPELQERMIKSSHEIEASGCGGSLLLLSGGHPLRRVWFANQLLPANSFVMLKAAHQLRKIGLLSPGLQLWCVENPLVNSIERLEQKINAGAEAVVVQPPLLPERFAEWWSKADQRGLTKATPVIVGLPLLTSSRNYSFWLELTGASGKEADAMKARWKRVESEHAGDSVAFARFCYKESVQLIESIRSLPGVAGIHVMPVTRAGWRQYQKLVSEGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0L7</accession>
    <name>A0A8T0I0L7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G080100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ARG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0L7"/>
    <dbReference type="OrthoDB" id="1864078at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009733">
        <property type="term" value="P:response to auxin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003676">
        <property type="entry name" value="SAUR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31374">
        <property type="entry name" value="AUXIN-INDUCED PROTEIN-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31374:SF419">
        <property type="entry name" value="SAUR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02519">
        <property type="entry name" value="Auxin_inducible"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="18142" checksum="450065D313B3DB3F" modified="2022-10-12" version="1">MPNKGVSGKMHKAFQKLQKSISNSNLHYQSIHHNDATSPPKMGGSVRNGCVFGRSGRFAGSDHDFDSDSDDSAPYDVPEGFLVVYVGGERRRFVIKAKYLTHPVFKALLNKSAEEFGYEHKGGLEIACEVNFFEHLLWLIESKNPSLSSMEFEELVGFYAYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I109</accession>
    <name>A0A8T0I109_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phytochrome</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G102500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">Contains one covalently linked phytochromobilin chromophore.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the phytochrome family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I109"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009584">
        <property type="term" value="P:detection of visible light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017006">
        <property type="term" value="P:protein-tetrapyrrole linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009585">
        <property type="term" value="P:red, far-red light phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16932">
        <property type="entry name" value="HATPase_Phy-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000034">
        <property type="entry name" value="Phytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000039">
        <property type="entry name" value="Phytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.270:FF:000001">
        <property type="entry name" value="Phytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013654">
        <property type="entry name" value="PAS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044767">
        <property type="entry name" value="Phy_HATPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016132">
        <property type="entry name" value="Phyto_chromo_attachment"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013516">
        <property type="entry name" value="Phyto_chromo_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001294">
        <property type="entry name" value="Phytochrome"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012129">
        <property type="entry name" value="Phytochrome_A-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013515">
        <property type="entry name" value="Phytochrome_cen-reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043150">
        <property type="entry name" value="Phytochrome_PHY_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47876">
        <property type="entry name" value="OS08G0260000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47876:SF3">
        <property type="entry name" value="PHYTOCHROME 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08446">
        <property type="entry name" value="PAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00360">
        <property type="entry name" value="PHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000084">
        <property type="entry name" value="Phytochrome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01033">
        <property type="entry name" value="PHYTOCHROME"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00245">
        <property type="entry name" value="PHYTOCHROME_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50046">
        <property type="entry name" value="PHYTOCHROME_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 9" id="KW-0157">Chromophore</keyword>
    <keyword evidence="2 8" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="7 8" id="KW-0675">Receptor</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Phytochrome chromophore attachment site" evidence="10">
        <location>
            <begin position="214"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="608"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="12">
        <location>
            <begin position="742"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="11">
        <location>
            <begin position="893"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="9">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>phytochromobilin</name>
            <dbReference type="ChEBI" id="CHEBI:189064"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000084-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0576717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1121" mass="124054" checksum="A34D23EC6E2A8527" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2F4</accession>
    <name>A0A8T0I2F4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G123000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2F4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035864751" evidence="2">
        <location>
            <begin position="25"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="42313" checksum="E1C8316CEA62F6E3" modified="2022-10-12" version="1">MNFFRVVAVLALIFLFCLDLVTLAAGSGPDTLARPPVWNFTMAQCSLFRNEAVLRPFFYMWPESIKDVPFRYCCEYQPSGNLSPTSFNLSLYSNGPGNDSNTLIPAPYYDLGIIDKNISVYILPHFGWAGLPFRLRAPYRPPLYCEASDLYRLYKHRLGKASFQALIIAAVLVVILLVCYLLSRVASLICARRTFDGKIPWGELFLDSCHVVLLAFVGTFLIEAIGHSDIREWRSQLMYNSGIVYWLLTVLAVSSSAVRHGFHTAKLDKKKKMVELQAKKLFAQFAALFMMCTYLSLVEDVTGRRLDSVAGLTLGVVLGAAGFSVMEYEWYAYLHTILRIRDKEYLECRICGAPKCEICCHEAAAALGAGRAGLGQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2I1</accession>
    <name>A0A8T0I2I1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G148200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the amino acid-polyamine-organocation (APC) superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2I1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015203">
        <property type="term" value="F:polyamine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044566">
        <property type="entry name" value="RMV1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826:SF25">
        <property type="entry name" value="AMINO ACID PERMEASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45826">
        <property type="entry name" value="POLYAMINE TRANSPORTER PUT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="476"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="525"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0577326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="559" mass="63121" checksum="56C6ED0E07F031D7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5N6</accession>
    <name>A0A8T0I5N6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G176700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5N6"/>
    <dbReference type="OrthoDB" id="10556999at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051032">
        <property type="entry name" value="AP2/ERF_TF_ERF_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31985:SF273">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31985">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF042-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="9">
        <location>
            <begin position="56"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="152"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0577723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="326" mass="35817" checksum="3099367800AF6516" modified="2022-10-12" version="1">MVDKQRIRTSSAGCRRGSELLKPRRKKKQKQVMSSKKMVNEAGSSSADKEAATASKYRGVRMRAWGKWVSEIREPNKRTRIWLGSFPTAEMAARAYDAAVVCLRGTKATLNFPDSPPSSLPLCPSSREIQAAAAAAAAATPVAPSTDAVSVSLRAESPQNHSTVDSTVEQHDGVEQHSQSLSEAEPKPQNDNLAAFLSEQTKMEQSELTGDWTSGPAAGAQNTDDHCRECCIECRNMAQLDNERPNLHHETLLAAAESCPQQVTMKTEDMAQLLDSHQEDEDVHGLLHGLKESYLPMSPYTEDVIIPATVTNSDLWELDNLWNFAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I897</accession>
    <name>A0A8T0I897_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">STICHEL DnaA-N-like alpha-beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G080000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I897"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054506">
        <property type="entry name" value="DnaA_N-like_STI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23007">
        <property type="entry name" value="DnaA_N-like_STI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STICHEL DnaA-N-like alpha-beta" evidence="2">
        <location>
            <begin position="815"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="693"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="935"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="693"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="944"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="974"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1149" mass="127645" checksum="C6D751132EF5B61F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8D2</accession>
    <name>A0A8T0I8D2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G125300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8D2"/>
    <dbReference type="OrthoDB" id="641593at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36806">
        <property type="entry name" value="ADENINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="220" mass="23399" checksum="D834AC922B1F57BB" modified="2022-10-12" version="1">MGANAGPDTMPPPASGPAGAVGAGPAWAAPAAVIATLSSLSLALQSLFNRLASTRLSRGDAAGAERARNIANQVGNGLQWWTGLGTLSWDYVTNYVFQQSMSRGMGVSEALGHLTALSSIVGEVTNLRSDSERLQWIARNYSRAFTVAKSVMGNLLSVFDHDGAIRNCVLAIQRELLEGDLLRDVLRLGPNDLEGIVKMSKDLLQRIFVPAQPGQREGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I912</accession>
    <name>A0A8T0I912_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein 6, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G081100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I912"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020526">
        <property type="entry name" value="Ribosomal_cL38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36798">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36798:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN CL38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17257">
        <property type="entry name" value="DUF5323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770904" description="50S ribosomal protein 6, chloroplastic" evidence="2">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="92"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11224" checksum="ADF6AD1BE429C9DF" modified="2022-10-12" version="1">MAALMSSLASLTITPLSSAVPSRSTARSNGVSLLRIECSSHPQKKATAHHNKSRPKKRNPYDKNRHGPTVYKRLPKPPPIWGFDTSDLEQTEGASGATEASATAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I998</accession>
    <name>A0A8T0I998_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G068500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I998"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd06472">
        <property type="entry name" value="ACD_ScHsp26_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031107">
        <property type="entry name" value="Small_HSP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11527">
        <property type="entry name" value="HEAT-SHOCK PROTEIN 20 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="HSP20-like chaperones"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="5">
        <location>
            <begin position="39"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="20219" checksum="898E95AE0F009A52" modified="2022-10-12" version="1">MALSSFFGRRNNMWDAVADPLEAMVTLFDNAPATSFARDARAVASTSVDWKETPSEHVFKADLPGLRKEDVRVQIEDGRTLSISGQRQKEEVQKTDTWHRVERSSGSFMRKFRLPESADLDHITAKVDSGVLTVVVPKVEKKKKLEARRIEIGGGASSQPAAIAHEEKGEQNGAASTTPAHAPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAC8</accession>
    <name>A0A8T0IAC8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="12">EF-Ts</shortName>
            <shortName evidence="12">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">EFTS</name>
        <name evidence="16" type="ORF">KC19_4G168400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 12 13">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Associates transiently with chloroplast polysomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Component of the chloroplast ribosome 30S and 70S subunits, as well as polysomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the chloroplast ribosome 70S subunit, and at low levels, present in polysomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 13">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14275">
        <property type="entry name" value="UBA_EF-Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.20:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000051">
        <property type="entry name" value="RNA-binding transcriptional accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF10">
        <property type="entry name" value="POLYPROTEIN OF EF-TS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 12 13" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="7 12 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="S1 motif" evidence="15">
        <location>
            <begin position="146"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="15">
        <location>
            <begin position="275"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="87"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="211"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="382"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="543"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="491"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="579"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="616"/>
            <end position="629"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00063456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00065253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00065880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0580372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1086" mass="114473" checksum="18C6355F6788CB5A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC61</accession>
    <name>A0A8T0IC61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G176800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047126">
        <property type="entry name" value="RNF141-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109">
        <property type="entry name" value="RING FINGER PROTEIN 141-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="812"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="870" mass="98214" checksum="5515EFE2FE22150A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICF3</accession>
    <name>A0A8T0ICF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G153600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="157"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="33172" checksum="DD61501520E3108D" modified="2022-10-12" version="1">MGVDVNWAEFAFTQTHTHERHCPLPRLLQKFECLVEPLAPLNKVIPIENFKDPVHSMTTMVELGPTLHSLPVHPASGIPPKRNEPSPSTPIEDTKTFFMNLIQPLPSVGSMDNKEAFPSMEDAALSALKALKGPVQIIVDGEQMSLRTARHEAYGPVANISQHLEEEKELLKHVNKKLTENKDSFNRAVEEYEKSRSFLTIARGDPLSLLPSDGSDRVKENHNIFESLVVSCSKIVEIARKQVGVWEFQSQRQFMIVEKLALDLSTAEAKYGEVCLEIDSKVDKLRALLIFLNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID15</accession>
    <name>A0A8T0ID15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G200300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="14423" checksum="BBFD91C59F406FA0" modified="2022-10-12" version="1">MTTIHGNAHVNGAWLDLSQYSCSKVSLILKITQSFQIRCLKWQLGVPAGSASHGNSDVLPLGRDHSLKLTTSPLSLLPCSLPQHRYGDNERGTVAHDRGAGAASEVGKPRSSLRPSSAAGVSDLGLCVHHTIFMGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGG2</accession>
    <name>A0A8T0IGG2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G087800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="38651" checksum="A85F72198B5A999D" modified="2022-10-12" version="1">MLDTKVWVKHRTSWRHGRHMSSSLSSGIMSAVGPPVFMCTLLATFVTIFNQLVKENQLWPWIPALEVPSLPFYLTSAVLLLLLVFRASSSYNRYDEASKLWMLNASRARDITRQALAWIRSPNDTSKLFCLLRHVKAYAFCLQDHLTEETHLNSKLKEIMEPQELDAIMSAKHRPSHVLHMISNLVQQCNISEWEKMAMDDNISIFNTNLGECERILNTPIPLAYTLLTSRFLIMWHLALPFALSGECGWLTIPAAFLVATSLFYIEEVGVLIDEPFWILSLGPVTDGIVIEVDELLQYHEARSSLPYHMQDRSEIDDEEITIEASGFDGFDRQGLFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGH6</accession>
    <name>A0A8T0IGH6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UTP--glucose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G027000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="2.7.7.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDPGP type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.9" evidence="2"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003983">
        <property type="term" value="F:UTP:glucose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006011">
        <property type="term" value="P:UDP-alpha-D-glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.10:FF:000001">
        <property type="entry name" value="UTP--glucose-1-phosphate uridylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016267">
        <property type="entry name" value="UDPGP_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43511">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0582019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="580" mass="65104" checksum="012137F46C7084EC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGJ3</accession>
    <name>A0A8T0IGJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G263700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="242" mass="27476" checksum="B57B5D8158EA750F" modified="2022-10-12" version="1">MKGDTKLTSHFRVRISHRPEFFPLVRILPVARSCQDHTSKKEELTEAITSPDKLIAGRWLHGSISQVNDTGGQGCFLRRPHNRCQLPSTVSKWRQLYTCNSKGRDTESIAQRICKELETSLMTRECNSRESCRQSRCSEQRILRSLLTTVRVPLLLSQSQPNNSTCARAFKSAPTTTNEYICGASAAKLDLLHPVNKQQHPLALRFVFENLNISNKLGTWRRRVGKCFKSSPTLLYSKSQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH75</accession>
    <name>A0A8T0IH75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RHOMBOID-like protein</fullName>
            <ecNumber evidence="10">3.4.21.105</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G046700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serine protease involved in intramembrane proteolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.</text>
            <dbReference type="EC" id="3.4.21.105"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Membrane</location>
            <topology evidence="2 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="10"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002610">
        <property type="entry name" value="Peptidase_S54_rhomboid-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936:SF69">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22936">
        <property type="entry name" value="RHOMBOID-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="260"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="12">
        <location>
            <begin position="141"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0582261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="40813" checksum="F77CC39395448AD7" modified="2022-10-12" version="1">MDKSAPGFTRSTTPPKDGASARAVDSPDPKGEFRVRVHDHDDHIFEPSPAVPTKPQPFNPKKHRYLPIAVPVIMVGNIVVFILMMYYNNCPNNITAGRKCVGDWLKPLSFQPWDENPMLGPRSAAILKWGGLESNLVTKHGEGWRLASTIALNGGVLQLCFNLIVLLIVGTRMEFTFWFSKVSLVYIISGFGGSVLSALFIQNQVFAGAGGAICGLIGAGLADMFMNWPVTERKIFKLIDLILFLLISLGFGLMPQVDNFANVGGLATGFLLGLVLLKRPQKGFKDTRHLSQLEAFIVNNEDPDLPPVKMYKVSQRVVSWIAFIVVLGLLTAGTVILLLDKFRVNKGCSWCHYAACVPNLKWECPGIYANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II24</accession>
    <name>A0A8T0II24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G136200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13563">
        <property type="entry name" value="2_5_RNA_ligase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="196" mass="22171" checksum="DBBFD6409337A21E" modified="2022-10-12" version="1">MVLFARVVAARGVHFSASMATTVAPIVLTLELDSKSQQFFDTLRQQHFPKERSFLSAHLTLFHHLPGGSYDDIRTQVAAAAAAEAQLPIAVTGVRFLGRGVAYTLENQRLRALHKRFQKQWHEELTSQDRQKLNPHITVQNKVDEAVARELHRELAEQFQPFEATGTGLQLWAYRGGPWEPLEMFPFLKGGQNVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIU0</accession>
    <name>A0A8T0IIU0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G086600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035889591" evidence="1">
        <location>
            <begin position="17"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="40" mass="4383" checksum="0950144F54B92637" modified="2022-10-12" version="1">MSLCAAMLLCLPNTCCWKQTAKLTLLLQMSMQGCTRTSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKH1</accession>
    <name>A0A8T0IKH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G136700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="93"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="252"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="310"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="718" mass="78539" checksum="2F69794D739F8D86" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL83</accession>
    <name>A0A8T0IL83_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G119200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL83"/>
    <dbReference type="OrthoDB" id="2017365at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001510">
        <property type="entry name" value="Znf_PARP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00645">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01336">
        <property type="entry name" value="zf-PARP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00347">
        <property type="entry name" value="ZF_PARP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50064">
        <property type="entry name" value="ZF_PARP_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="12"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PARP-type" evidence="7">
        <location>
            <begin position="124"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="218"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="245"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="262"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0583223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="278" mass="30956" checksum="6E8CC05BB76297F4" modified="2022-10-12" version="1">MATETKAAHKPWKVEYAKSSRSSCRACGKPIAKDAFRLAKIQPAHQFDGLMPQWHHASCVFHKEDEITSLDEVDGLEDLRTADLQNLRKYIEGTLKASDREVDKGKSVAPVASAGGSGDNSGEYEIENAKSSRSVCKSCNEKIEKGHVRVATMVDNPRFRGKQPAWRHVKCFLELGWWTSPMAAMAGWDNLSVKDQGEVQELVKHSPGVKEAKFVEKVESHEVGSKRKKDASKSPSPKKSPRLSRIKEKIADAMSHKETSPVKHHTHVVKKRSPKKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPU3</accession>
    <name>A0A8T0IPU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cytochrome c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_3G238900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </cofactor>
        <text evidence="14">Binds 1 heme c group covalently per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.760.10:FF:000002">
        <property type="entry name" value="Cytochrome c1, heme protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="entry name" value="Cytochrome c-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.100">
        <property type="entry name" value="Cytochrome c1, transmembrane anchor, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002326">
        <property type="entry name" value="Cyt_c1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021157">
        <property type="entry name" value="Cyt_c1_TM_anchor_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266">
        <property type="entry name" value="CYTOCHROME C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10266:SF3">
        <property type="entry name" value="CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02167">
        <property type="entry name" value="Cytochrom_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00603">
        <property type="entry name" value="CYTOCHROMEC1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="Cytochrome c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81496">
        <property type="entry name" value="Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Cytochrome c" evidence="17">
        <location>
            <begin position="115"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="164"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="14">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>heme c</name>
            <dbReference type="ChEBI" id="CHEBI:61717"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR602326-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0584846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="332" mass="36305" checksum="FC008F543ED9B529" modified="2022-10-12" version="1">MAGRRVFGGINCEGGMLLARRFGVWKERRDGTCFVQKCGLPTNLLPNRSHGFYQSSGKRNTWKSKGSNIVTFAGAGAMGLLGMAGSAYADEAEHGLAAPSYPWANDGWFASYDHAAIRRGHQVYKEVCAACHAMSLIAYRDLIGVAYTELEVKALAAEIEVEDGPNDDGEMFGRPGKPADHLQPPYANEQAARSANGGAYPPDLSLICKARHNGPNYVFALLTGYRDAPAGISVRQGLYYNPYFPGGAIAMPRVINDGGVEFEDGTPATSSQMAKDVTHYLAWAAEPEHDERKLIGAKWICGALLCLYAMGYYKRWKWGPLKSRRIIWDVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ90</accession>
    <name>A0A8T0IQ90_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G047700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="15458" checksum="DA6B58E464D7582E" modified="2022-10-12" version="1">MLCCSSMLTVSRSTPPSSPSAGSHGLVSSSTVSMCNSDASFVGSDGLLSNVTNSCRSFVHVVKQVLESTYLRIPLPRLSAGFLDGKKERIASLLSAAAKLSLCASVGKTVLEPRCSRIPLGLSAGIMDGDTGSGKLLTVRRGDVDSECF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRC9</accession>
    <name>A0A8T0IRC9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G078900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11175" checksum="DC8CD28735137778" modified="2022-10-12" version="1">MCERHHVSFVSGSFCLRNRWLCRLLSRSSYISASESLSLGGHPSMIHPTPPRATPRTSSRGTQSRTCSAPLRQFHTQPSTFTLNNHIPNEGNPIPIPLQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS52</accession>
    <name>A0A8T0IS52_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">DNA polymerase delta catalytic subunit</fullName>
            <ecNumber evidence="3">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_2G045400</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>DNA(n) + a 2'-deoxyribonucleoside 5'-triphosphate = DNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA polymerase type-B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS52"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008296">
        <property type="term" value="F:3'-5'-DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006287">
        <property type="term" value="P:base-excision repair, gap-filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045004">
        <property type="term" value="P:DNA replication proofreading"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="entry name" value="DNA polymerase family B, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.342.10">
        <property type="entry name" value="DNA Polymerase, chain B, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.690">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="entry name" value="Ribonuclease H-like superfamily/Ribonuclease H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006172">
        <property type="entry name" value="DNA-dir_DNA_pol_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006133">
        <property type="entry name" value="DNA-dir_DNA_pol_B_exonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050240">
        <property type="entry name" value="DNA_pol_type-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025687">
        <property type="entry name" value="Znf-C4pol"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322">
        <property type="entry name" value="DNA POLYMERASE CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10322:SF35">
        <property type="entry name" value="DNA-DIRECTED DNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03104">
        <property type="entry name" value="DNA_pol_B_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14260">
        <property type="entry name" value="zf-C4pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00106">
        <property type="entry name" value="DNAPOLB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00486">
        <property type="entry name" value="POLBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="DNA/RNA polymerases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="Ribonuclease H-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DNA-directed DNA polymerase family B exonuclease" evidence="20">
        <location>
            <begin position="419"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed DNA polymerase family B multifunctional" evidence="19">
        <location>
            <begin position="644"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="domain" description="C4-type zinc-finger of DNA polymerase delta" evidence="21">
        <location>
            <begin position="1135"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="344"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="346"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="18">
        <location>
            <begin position="360"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00049244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF03104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF14260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0585865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1230" mass="135511" checksum="EAAEBCAFF1EF3BA7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITZ0</accession>
    <name>A0A8T0ITZ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G072300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.80.10:FF:000015">
        <property type="entry name" value="Heme-binding protein soul2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF71">
        <property type="entry name" value="SOUL HEME-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035909545" evidence="2">
        <location>
            <begin position="21"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="227" mass="25015" checksum="A8826E3358E62E29" modified="2022-10-12" version="1">MGCGDYLVVLVLLVVYSCVAFTVVESAVVPLPESVLRWFGIAGEEAGSCGPQLEIATPACKVVETRKEYELRKYNTEIWVETLVGNSTFESATSTGFYRCFDFISGKNSEGMKIEMTSPIHITPAPHTNGYKVAFFVPSRFKAVKDLPTPQDSEVHIYQSKGAVKAVIGPFGGFPSDKDYEAKAAELKKALDKDGLKYDETTVLYAGYSSPFQFRNRKQEVHVNVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUW8</accession>
    <name>A0A8T0IUW8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Transcription-repair coupling factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G128500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17991">
        <property type="entry name" value="DEXHc_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="entry name" value="Transcription-repair-coupling factor, D7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_RID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_RID_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047112">
        <property type="entry name" value="RecG/Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47964">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47964:SF1">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_TRCF_RID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="CarD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="TRCF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="462"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="644"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="132"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="141"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="266"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0586932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1000" mass="110587" checksum="0043DA98A41DFBAE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWX9</accession>
    <name>A0A8T0IWX9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_2G182600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="5"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000044">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000073">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="16">
        <location>
            <begin position="129"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0587675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="438" mass="49087" checksum="49B3FDACDA83DD17" modified="2022-10-12" version="1">MMSSSLNHRRVEVLPGNEKYTPKAQKQWSLAKSVEYVLREQRFMFVLIGVAITTLFFMFLQPELRFAGRYSEASSSSSLGGVRVFERESVGGVGGSGDVPYRRQQVAAVVGSGGKIPLGLQRKALRIVVTGGAGFVGSHLVDRLIERGDSVIVVDNFFTGRKENVMHHFGNPRFELIRHDVVEPLLLEVDQIYHLACPASPVHYKFNPIKTIKTNVVGTLNMLGLAKRIGARFLLTSTSEVYGDPLEHPQKETYWGNVNPIGVRSCYDEGKRTAETLAMDYHRGAEVQVRIARIFNTYGPRMCIDDGRVVSNFVAQALRKEPMTVYGDGKQTRSFQYVSDLVEGLMRLMEGEHVGPFNLGNPGEFTMLELAEVVKEVIDPSATIEYKENTSDDPHKRKPDISKAKELLGWEPKVALRQGLPLMVEDFRKRIFGDHKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYF0</accession>
    <name>A0A8T0IYF0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G190700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYF0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7668" checksum="4B1BE6984AEBA1E0" modified="2022-10-12" version="1">MEFSRTQGKYGTVTYGRSRGIEVCRPLCSLCKHLLSSTTSRTPPALHLELTSNSEIAHSKRNSKCRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYJ2</accession>
    <name>A0A8T0IYJ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G238400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6408" checksum="78E6D46769FB66B2" modified="2022-10-12" version="1">MREGRRAAFYIKCVLSCINVMLISAKGLDPQRKQELVKRKRNIGGDVSRSWRWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZT5</accession>
    <name>A0A8T0IZT5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G197900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747:SF2">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="100"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="587"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="911"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1150"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1184"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1234"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1253"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1281" mass="144752" checksum="5E992F1BBE0CFC0B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J148</accession>
    <name>A0A8T0J148_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G261800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J148"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="126"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="50379" checksum="ABEF8774CEDFA0C8" modified="2022-10-12" version="1">MGNANSRVRHLPDVFCVCMGRSSEARDVAGSAAEDAASSPSPQLPACSASNYVVGEVGSESVEQQIEQSMSHWSHLTQIDSDCIDEEDVEADNMEVFLALQSDPSTKEFFRTFGYDSELWKSSGSLEIGHKFAEGGQAELFHANVTWSNLKGNKRDREHGREWVLKVFKKGTRLRHLQSQWPHGMLKFHEEQVANWRSPTPKTIPRFFCEVFRGTLLEDGRFAFLMKKEHLDLRRLIDDKMKLIAPNNRGPFSKEVAEELMFEIALGMSWLHSRDIVHRDLKASNVLIQVHDDDDFQCFVADYECSIGVVGTGLFRAPEILEACKEKSVSKRLELFTMASDVYSYGMTCYEILTGKFPFNGQSGNDIMDVVIGGKRPEVPEYVDEWVHKLLSDCWQHDPTKRPSFGEIVNFIYSNSLRIRGLIKRGVTYRMDRMDWIKLEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4E9</accession>
    <name>A0A8T0J4E9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G047600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4E9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd11449">
        <property type="entry name" value="bHLH_AtAIB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045084">
        <property type="entry name" value="AIB/MYC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054502">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025610">
        <property type="entry name" value="MYC/MYB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11514">
        <property type="entry name" value="MYC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11514:SF43">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14215">
        <property type="entry name" value="bHLH-MYC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22754">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="533"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="273"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="370"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="456"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="618"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="579"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="396"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="633"/>
            <end position="647"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0589778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="751" mass="82654" checksum="5581EBABAF911A11" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5B4</accession>
    <name>A0A8T0J5B4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G126500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5B4"/>
    <dbReference type="OrthoDB" id="2161780at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051151">
        <property type="entry name" value="Group_II_Decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002748">
        <property type="entry name" value="PRK02769.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46101">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46101:SF2">
        <property type="entry name" value="SERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0590787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="496" mass="55550" checksum="0153FFDDDCA860E3" modified="2022-10-12" version="1">MGGSVEAVTVGAENGFSKKRALSPVAAEELPEEIPFDSLKTVLPALVGEAKEDVVVEQTKNFVLGKNVHGTCLEITEPGLDDEETGDRDAYMAGILSRYRKTLVEKTKYHLGYPYNLDFDYGALSQLQHFSINNLGDPFIESNYGVHSRQFEVGVLDWFARLWEIEKEDYWGYITNCGTEGNLHGILVGREVFPDGILYASKDSHYSVFKAARMYRMESVKIDTLLSGEIDCADFERKLSERKDKPAILNVNIGTTVKGAVDDLDLVLKTLEKVGYTEDRFYIHVDGALFGLMMPFVKKAPKVTFKKAIGSVSVSGHKFVGCPMPCGIQITRMRHINCLSQNVEYLASRDATIMGSRNGHAPLFLWYTLNRKGYRGFQKEVQRCLRNAHYLKERLREANIGVLLNELSSTVVFERPLDEAFILKWQLACQGKIAHAIVMPSVTVEKLDDFVEELIAVRKRAFPDGNVVVPCIVEEVGPENCACSVHRDTVSSPKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5G8</accession>
    <name>A0A8T0J5G8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G125600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5G8"/>
    <dbReference type="OrthoDB" id="1937973at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="18681" checksum="CCAB5C3B551C4D9E" modified="2022-10-12" version="1">MAMAACQAQCVQQSLNYLAQGTSSLEVRNRPATVSFTRTATKNVQGLSQRGKARLVICAAEGSGSCCGGSEGSSSGKQSCSSHGSKAPPPGVAGVGAEFENMVSRSTMQEFEKEYDTGEMQGTITRDVVADVMNEIPEILNASNEEKFVDVDAVLSEAMRLANEDFVFDEFEGTMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5I3</accession>
    <name>A0A8T0J5I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G071100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5I3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050983">
        <property type="entry name" value="GST_Omega/HSP26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43968:SF14">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51354">
        <property type="entry name" value="GLUTAREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="175"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="538" mass="60018" checksum="23A5F9FC317A5D7A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5Y1</accession>
    <name>A0A8T0J5Y1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G082300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5Y1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33115">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33115:SF50">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="626"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0590221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="927" mass="103209" checksum="BEC2C75D89948BF3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8U5</accession>
    <name>A0A8T0J8U5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor MYC/MYB N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G192100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8U5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025610">
        <property type="entry name" value="MYC/MYB_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46633:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE WNK (WITH NO LYSINE)-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46633">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYC/MYB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14215">
        <property type="entry name" value="bHLH-MYC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor MYC/MYB N-terminal" evidence="4">
        <location>
            <begin position="18"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="228"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="315"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="481" mass="52821" checksum="FAF53A80CA285947" modified="2022-10-12" version="1">MDSRQAGGMLPAMNPMLLQHTLRGLCTDSQWVYAVFWRILPRNYPPPQWDTDGGIMDRSKGNKRNWILVWEDGFCDFSACASGTGNESTRAASSSFLATRQLRPNVDDEPEAMNPELFFKMSHEVYNYGEGLMGKVAVDNSHKWVYKEPLENEISFLSPWHASLDPHPRTWEAQFKSGIQTIAVVAVQEGVLQLGSTKRVMEDLSFVLYMQRKFNFLHSIPGVFVPHSTSGSGTKRPSPPTGLPLPSPFDASQSHSQLTLRSIDQFLSPRMGAPDLWRPMSNIPSTGVTGMKRPPEPTSQSLNLKEYAYFNGFECRPESSPSPPKALNTGHTSPQGATSPTLPTLLPSMSSLQALLSKLPSVTHSLDAESTIHGLPSSGIPCTGFTSNRPPISRSVSKAPKEEICNGKRMLKGEVMDSGSTSDVGDVDTVDDPQPSCNMADHAHESTTFLESFENLNEYGIPEALENGDSSYSSFLNEICS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J984</accession>
    <name>A0A8T0J984_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G239000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J984"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46862">
        <property type="entry name" value="OS07G0661900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46862:SF3">
        <property type="entry name" value="OS07G0661900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="217"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="287"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="322"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="392"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="56684" checksum="D3CCD25CD75D9F18" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9Y5</accession>
    <name>A0A8T0J9Y5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G212900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.330:FF:000079">
        <property type="entry name" value="Protein SRG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050295">
        <property type="entry name" value="Plant_2OG-oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47991">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="5">
        <location>
            <begin position="232"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0591932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="43717" checksum="AF74C5E5670BD19E" modified="2022-10-12" version="1">MAEATALREVITTSDFEQHNATEQKGAELAVSVDTSEMVQYMVEKGLKEVPPEYVLPHKHRPSATKTKNLPGNLRIPVIDMGDFHHKDGAERVIGEIGRACEEWGFFQVINHGLPAALMQEAMEMCREFFALPMEEKELYSMKTSSGIGYGRRFAVKEGARVDWVDRLGFWSASEEHRMRQPLHIKRPVAFNETMAQYGDEILKLAHLILTALSRHADLPSEYLLERLGEAKAAGVRTGMNYYPPCPQPDLVMGIGSHADGSVLTIVQQDGTPGLEVLKDGLWVPIPAMSDAFVINIGDQIQMISNDRYKSVVHRVTAGAGRKSISNFFLPGWETTISPAPRFCSSSDPPRYRPVKFSEYITEFMKVPLGEGRFVDNFRVPRSLSGDSMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD48</accession>
    <name>A0A8T0JD48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G268700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="2">
        <location>
            <begin position="812"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="870" mass="98095" checksum="EAB29D952358A86F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G660</accession>
    <name>A0A8T0G660_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase assembly factor 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G098900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G660"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9788" checksum="F568D5CBAD29EA32" modified="2022-10-12" version="1">MMADGDGKPQVHKSCRALALSLVKCLDESACMQGEKRSYKDCALDENMAASPACRDIRDTYMKCKHEQVGLVVRERIFNNPELLRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7V9</accession>
    <name>A0A8T0G7V9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WLM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G146000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7V9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd10463">
        <property type="entry name" value="PUB_WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013536">
        <property type="entry name" value="WLM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47796:SF1">
        <property type="entry name" value="OS08G0500800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47796">
        <property type="entry name" value="ZINC METALLOPROTEINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08325">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51397">
        <property type="entry name" value="WLM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WLM" evidence="2">
        <location>
            <begin position="131"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="324"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="634" mass="69180" checksum="B61B9775396BD95A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8D3</accession>
    <name>A0A8T0G8D3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G067900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8D3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="12028" checksum="D0B5F5D08D82CE5F" modified="2022-10-12" version="1">MLGNGLSQLNSSQQILQSVKLTVWVPKWRPKRTDILKEDQFYSQWLIIATLEGARVCRQHSDPSFRDPPLKTAVKPIGSGVIIRLVICMQFILTRSNRYFARDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBE3</accession>
    <name>A0A8T0GBE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G148300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the Hakai family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBE3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030155">
        <property type="term" value="P:regulation of cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040383">
        <property type="entry name" value="HAKAI/CBLL2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13480:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HAKAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13480">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035747121" description="C2H2-type domain-containing protein" evidence="6">
        <location>
            <begin position="31"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="7">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="146"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="229"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0555158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="455" mass="50360" checksum="9D7DB0323131BF4D" modified="2022-10-12" version="1">MFVHCNRLCWGHARLTACVCIFCIWLQIPCEHVFCLTCAKLDPTCFLCEERVTRIQKMDVLEGIFICGAPGCLRSFLARPDFDNHISDAHSQLLQLEQGRLSPERNISAGNPVPEAQAQSHQGGQQYADLAPPMRQSSGTLQVLLPKKEEQPQRRPPKSVRQDPQGVLARPVPELRLPDQFPRHRGGDQHSNQSNYDIGNDMERHEPRRDRKPRRHSEWDTQVPQGQGENEREYMHEGEPQRERRGDGSSGRTKERDGDKGSHPSSIPAPKDPSQQLASLPPPPPYPPPNFSTAYPPQQEGNATFPSRFDASRAFHPGMPLPSRPEGFNQNGPPRPPLDGYGQSGGPPRPMNGQAAQDQFGHNRSLRPHFYPEYGPGPVMGMPPMGAPRYHEGHLPPPPPGPPPKRAKFNGPQGSGEPMMEPYSWGPGNPANFGGPPGGHANYGGPQNWMPPANS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCJ5</accession>
    <name>A0A8T0GCJ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G036500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46601:SF1">
        <property type="entry name" value="ADF-H DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46601">
        <property type="entry name" value="ULP_PROTEASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="752"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="774" mass="88646" checksum="0FAB8E5C9F742E45" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDG2</accession>
    <name>A0A8T0GDG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_11G062500</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000019">
        <property type="entry name" value="Sodium/calcium exchanger NCL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF36">
        <property type="entry name" value="SODIUM_CALCIUM EXCHANGER MEMBRANE REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0050">Antiport</keyword>
    <keyword evidence="10" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="16" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="12" id="KW-0346">Stress response</keyword>
    <keyword evidence="7 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="203"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="233"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="330"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="571"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="643"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="671"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="698"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="428"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="18">
        <location>
            <begin position="469"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0556557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="724" mass="78497" checksum="3349BC37578EDE7F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEY9</accession>
    <name>A0A8T0GEY9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G113200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEY9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035881780" evidence="1">
        <location>
            <begin position="19"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8468" checksum="EF0561B711C4D9BB" modified="2022-10-12" version="1">MCLYFCSICLLLKRPLAGRAPSLLIEDLNDITVSMFTSSRLFSLELGYCVKEMFVLQYPIGLRSLTSSNLPGVCKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH17</accession>
    <name>A0A8T0GH17_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G165100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051063">
        <property type="entry name" value="PDI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672:SF11">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45672">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="144"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="288" mass="32978" checksum="72FCAE2116C62899" modified="2022-10-12" version="1">MSMWDYNEEGDPYPPNDSRQYRNPYASHSDSSDYHGGYAGHQSHSGHNHSHDGHHGHDHVEHDNPYSYHGQRSEGSSSRQNYGSRHESYAGHGDHQGHRHASHGNYGHDHGHESYVSPSHSSNNIQSSITQSTHHGRGQQNYDMSVGYEIRQEHQPPPPISSGHGHEVGNRDLFTSDSVVNLTLDEIDALARTHRSRSWLVVLYAPWCRFCQAMEPNFERVAHHLEQSNVYVGRFRADGDYKEYAKRYLQLEHFPTVLFFPKNSSNIVKYQSENREVDALLGFVHAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK51</accession>
    <name>A0A8T0GK51_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G139000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="13713" checksum="1C094627B9F16FE9" modified="2022-10-12" version="1">MHKDGTSLGLGSSVLSPRKHIQTSRHRHSPCPCCADLILNALATPPRYRLLLLRLLWLLGYRGSTTGITGVGARLARSGLEVHGTMRAIIQWNERLIISQLVRVGCCGGYNSDVIVTEGRDPVGLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKG7</accession>
    <name>A0A8T0GKG7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G046200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010301">
        <property type="entry name" value="RRP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026">
        <property type="entry name" value="NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13026:SF0">
        <property type="entry name" value="RIBOSOMAL RNA PROCESSING 1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05997">
        <property type="entry name" value="Nop52"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="421"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="514"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="448"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="514"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="551"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0558679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="642" mass="70091" checksum="2088877151385C30" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMW6</accession>
    <name>A0A8T0GMW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G022000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMW6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="167"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="601" mass="68116" checksum="945ACA88FC890530" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNI9</accession>
    <name>A0A8T0GNI9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">O-methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G129700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNI9"/>
    <dbReference type="OrthoDB" id="1606438at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11746">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005739">
        <property type="entry name" value="O-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="6">
        <location>
            <begin position="45"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="5">
        <location>
            <begin position="166"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR005739-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0559799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="400" mass="43387" checksum="83527768A3CFDB7D" modified="2022-10-12" version="1">MAVSENGASKLQMAQHGSIDDGARDIDAVGRNRLALSQIGIAWTESAALRTVVELDVPRILAKHAAPPDHAMSAQQLLQCMPRASNPNAGALQHLMQLLACKGLFTEHLEYHNSSGVAGDHLGGSVVRTYALNSISRQLVGDNPSDSMANFALQMTMGPHVAATLQHLGEAILTSADPFQLAHGVNYFEFLAKHPEYLNVFQNAMAERSQAETGPLLLTRYKGFNSVKGLMDVGGGTGAILAQIVRHYPHITHAVNFDLPEVVALSPAHPGVEHVGGDMFESIPVGCDAIFMKKLLHDWDDEACIKILKKCYEALPESGGKVILVEGVLSPKETPGNTNAKSNTMEDEFVLRSSVIMFVHCVGGKERSEHDFHRLVTAAGFRNFQLLCKLDVSYVMEAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNX8</accession>
    <name>A0A8T0GNX8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G142200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNX8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12638" checksum="9D275FE7C0AB9000" modified="2022-10-12" version="1">MTAQVLALALLVHDAPPPNNIIPSLPSFLPSLHCIALHCIACSPLHPSAHSLSPSPPHSTNNQSPNPYLPASHTTTALFLISQLTYNSLLFTQFHLLNPKPSVWISYGGRASAFSHNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP98</accession>
    <name>A0A8T0GP98_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_9G010400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP98"/>
    <dbReference type="OrthoDB" id="10254671at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005956">
        <property type="term" value="C:protein kinase CK2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14132">
        <property type="entry name" value="STKc_CK2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000059">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000088">
        <property type="entry name" value="Casein kinase II subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045216">
        <property type="entry name" value="CK2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24054:SF0">
        <property type="entry name" value="CASEIN KINASE II SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="140"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0560753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="50622" checksum="AA8D526CCEFBEB6C" modified="2022-10-12" version="1">MLLGRLPNWGAGAGLGGASIWAGACRRIVVNASLGAVASAQRRSVGGAVCERDQAFFDSLPKAFRELLRKRPSPEQARQQDEVLAHPPPFANLAQKIGKSVRRPGVMSKARVYTDVNVQRPKEYWDYEALTVQWGDQDDYEVVRKVGRGKYSEVFEGINTVNNERCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQQSKTPSLVFEYVNNTDFKVLYPTLTDYDIRYYIHELLKALDYCHSQGIMHRDVKPHNVMIDHEQRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYALDMWSLGCMFAGMIFRKEPFFYGHDNYDQLVKIAKVLGTDELNAYLTKYRLELDPHLEALVGRHSRKPWSKFINADNQHLVAPEAVDFLDKLLRYDHQDRLTAREAMAHPYFYPVRSMEASNRRSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQA1</accession>
    <name>A0A8T0GQA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G182200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="14068" checksum="29C3D58DB7AF8D45" modified="2022-10-12" version="1">MILCETSILNISASRPPQITSLLPHWNQNRSKPTATTLSYNPQHGQVKHNERSPRYQLVTHRSCSTLVEQRIALNSIMILLQAHRMQSKLKTRQTSSRTSPQRWNESLQLLLLTRFSTHANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQJ4</accession>
    <name>A0A8T0GQJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G018500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="248" mass="28317" checksum="C056965D7C562424" modified="2022-10-12" version="1">MLVPLVAFSATLFSALDSTGIFKYQDHPAFVWCAVALTGVVALITLCFSFMTFLTAPGSKLRHILHSATVMLAAHESDRVLAFYRRNGLTYGHYSNPITNRLEREVVSEFMSLVERKGLKDVPFEDQERPHEDVNPHRQLYSFQYENFTWVNALIDPVHKEAQFTVSQRGKKQCYLTCPFEQYRFGHLLGVLRWLQSNQKQGIWETVKFVGSKRIARCLSFESIFVAAMDGDGFDLVPLKVPQTMILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVF9</accession>
    <name>A0A8T0GVF9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G083500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="492"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="523"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="7">
        <location>
            <begin position="284"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="10">
        <location>
            <begin position="384"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="602"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="602"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="659" mass="73707" checksum="DCC2C13DE4CD73E7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVJ1</accession>
    <name>A0A8T0GVJ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G182400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVJ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="15118" checksum="31441CD6DF983273" modified="2022-10-12" version="1" fragment="single">MLMNYLELHQAQTPELRATCTTLIEHASSNQPSDNNARLIPTQTPTTEKLRRKDKVQTPTCLASSSRPDNSRDLWNLQPSLRVPVTHPSYLDWSCRYPPGRASSASNLAACVAILELGHSLCSLPGRLVLPFVLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX12</accession>
    <name>A0A8T0GX12_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="14">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_8G031900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = (2R)-3-phospho-glyceroyl phosphate + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="14"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX12"/>
    <dbReference type="OrthoDB" id="1152826at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd18126">
        <property type="entry name" value="GAPDH_I_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05214">
        <property type="entry name" value="GAPDH_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000001">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000020">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000636">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase 2, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836:SF112">
        <property type="entry name" value="GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE GAPC1, CYTOSOLIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyceraldehyde 3-phosphate dehydrogenase NAD(P) binding" evidence="15">
        <location>
            <begin position="11"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="20"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="159"/>
            <end position="161"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="219"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="12">
        <location>
            <position position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0563443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="346" mass="37264" checksum="6578791600380486" modified="2022-10-12" version="1">MTVGAEGKAKIKVGINGFGRIGRLVARVALERDDIELVAINDPFISPEYMTYMFKYDSTHGQWKKSDVKLHSENQLTFGGNPVTIYGCRDPSEIPWGKHGADFVVESTGVFTDKDKAAAHLKGGAKKVVISAPSKDAPMFVMGVNEDKYTNEDIVSNASCTTNCLAPLAKVINDKFGILEGLMTTVHATTATQKTVDGPSNKDWRGGRSASTNIIPSATGAAKAVGKVLPELNGKLTGMAFRVPTTDVSVVDLTVRLEKPASYETIKAAIKEASEGKMKGILGYTEDDVVSSDFITDSRSSIFDAKAGIALSDTFVKLVSWYDNEWGYSNRVVDLIAHIAKQGNSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXP1</accession>
    <name>A0A8T0GXP1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G119000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="15930" checksum="D533BD3E51DED56F" modified="2022-10-12" version="1">MITGLVEIEASYGGCCPPLYMDCDNNATNGCETNIVGDVKNCGSCGTLCHPMPPSFHAHVYCTNGICEYICEYDAGDCDYDIVSNGCETNLSGIDPNNCGECASHCADYTSELPDGQADSPYYYVDISAGNRIRTAKIFQFRLMLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY61</accession>
    <name>A0A8T0GY61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G126300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="28"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8759" checksum="84A4B2D0C94CC32B" modified="2022-10-12" version="1">MDDQALELWRPPKRRRGQCSSSFAATDVDYDVFLNHRGPDVKAGFVAHLDEALRAAGLNPFLDKASLRKGDPAFTSMPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2Z3</accession>
    <name>A0A8T0H2Z3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G065000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2Z3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000010">
        <property type="entry name" value="Transcriptional activator Myb isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF285">
        <property type="entry name" value="TRANSCRIPTION FACTOR MYB98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="630"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="634"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="682"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="682"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="230"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="427"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="482"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="496"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="508"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="841" mass="91833" checksum="8CB66E01162A8D69" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3K6</accession>
    <name>A0A8T0H3K6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G150900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3K6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035825981" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="122" mass="13515" checksum="1A40E9B0851ECE3B" modified="2022-10-12" version="1">MGVILLLLPFLGFRNHASNLDSGALNFVALFCVPMFSSTSRNGTVGDHCNHQNESLSNQCIVCCSSLQFVQLSEGWGGKCVAVMCNSFHFRVGYVIVYLHEMGCRLGYGKIYFLRIWVLAPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H454</accession>
    <name>A0A8T0H454_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Protein disulfide-isomerase</fullName>
            <ecNumber evidence="4 13">5.3.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_7G081300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>Catalyzes the rearrangement of -S-S- bonds in proteins.</text>
            <dbReference type="EC" id="5.3.4.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.4.1" evidence="4 13"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H454"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02995">
        <property type="entry name" value="PDI_a_PDI_a'_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02982">
        <property type="entry name" value="PDI_b'_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02981">
        <property type="entry name" value="PDI_b_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000152">
        <property type="entry name" value="Protein disulfide-isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005788">
        <property type="entry name" value="PDI_thioredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005792">
        <property type="entry name" value="Prot_disulphide_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01130">
        <property type="entry name" value="ER_PDI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01126">
        <property type="entry name" value="pdi_dom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF132">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10 11" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035969982" description="Protein disulfide-isomerase" evidence="13">
        <location>
            <begin position="22"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="5"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="14">
        <location>
            <begin position="335"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="55"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="401"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605792-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU361130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0566686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="55089" checksum="533DC92F32D9EF1C" modified="2022-10-12" version="1">MAVQSWIGLLVVLLVVPWVGASVSEEDVLVLNVDSFDETIKAHPFILVEFYAPWCGHCKKLTPEYAKAATELKSHDPPIVLAKVDVNDEKNKPLASKYGITGFPTLKIFKKGGSIISDYKGPREAAGIVAHLKQLVGPPSSEITSAEQAEEIVKKSQLTVVGVFKSLDDKEYSDFVSVADELRGDYQFVHTLDTSFVPDKGVALVAPAVRLYKRFDEGFNDAEDLSLEGLKKFLEEKSVPLVTEMNKDPASHSFLLKFFNAVATKAYLLLDLKADTADSYRTTYAEMAKTYQSKGIRFLIADSTENDNAVKFFGIKDSGLPALVVQAKDDNEKYVANNIKASDMSAWLEDFQDGKLEAYLKSDEIPEKNDEPVKVVVRKSFNQMVLDSGKNVLVEFYAPWCGHCKKLIPTLNALAVEFKDDDDVVIAKMDATTNDVPQGLFNVKGFPTLYLHTATGENIRYEGNRSQSDLSEFIKKHRSSVPKSAGSADEVVDAKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H526</accession>
    <name>A0A8T0H526_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G190000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H526"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="59"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0565429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1201" mass="133279" checksum="8B24131F7595B494" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8F3</accession>
    <name>A0A8T0H8F3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Nucleoside diphosphate kinase</fullName>
            <ecNumber evidence="17">2.7.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_7G099500</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Shows the highest specificity towards GDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast thylakoid lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15 16">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="17"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8F3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04413">
        <property type="entry name" value="NDPk_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.141:FF:000005">
        <property type="entry name" value="Nucleoside diphosphate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="entry name" value="Nucleoside diphosphate kinase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001908">
        <property type="entry name" value="PRK00668.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11349">
        <property type="entry name" value="NUCLEOSIDE DIPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="Nucleoside diphosphate kinase, NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51374">
        <property type="entry name" value="NDPK_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="9 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleoside diphosphate kinase-like" evidence="18">
        <location>
            <begin position="85"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="15">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00058621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0566957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25039" checksum="6C81379F427578CD" modified="2022-10-12" version="1">MVRARLASGLARAARAATQAPRQALFSEGRAALATSAARNSGAAATAVRASAGTNGGYSRWFPAAAFLPAAAYMALDQTVEAAELERTFIAIKPDGVQRGLISEIVGRFERKGYKLVAIKLIVPTKEFAAQHYDDLSSRPFFDGLCDFLSSGPVVAMVWEGQGVIKYGRKLIGATSPQASEPGTIRGDLCVQVSRNIIHGSDGPETAVNEIGLWFKPEELVSYTKNDEKWLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9C8</accession>
    <name>A0A8T0H9C8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exocyst component Exo84 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G006800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO84 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9C8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1210:FF:000002">
        <property type="entry name" value="Exocyst complex component EXO84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1220:FF:000001">
        <property type="entry name" value="Exocyst complex component EXO84B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1220">
        <property type="entry name" value="Exo84p, C-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1210">
        <property type="entry name" value="Exo84p, N-terminal helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033961">
        <property type="entry name" value="Exo84"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032403">
        <property type="entry name" value="Exo84_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042561">
        <property type="entry name" value="Exo84_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042560">
        <property type="entry name" value="Exo84_C_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21426:SF12">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16528">
        <property type="entry name" value="Exo84_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08700">
        <property type="entry name" value="VPS51_Exo84_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst component Exo84 C-terminal" evidence="6">
        <location>
            <begin position="169"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="787"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="18"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="809" mass="88366" checksum="5DC87233454015F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCP8</accession>
    <name>A0A8T0HCP8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G171600</name>
        <name evidence="3" type="ORF">KC19_7G171900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCP8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274488" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="7439" checksum="99C321982050D727" modified="2022-10-12" version="1">MSNDMLLVLLLVLPMTRPALQTNLQARYFYCCKWFHKHYQKPRPWTLPWNASSLLVLFDLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD88</accession>
    <name>A0A8T0HD88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Arp2/3 complex 34 kDa subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G008400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the Arp2/3 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell projection</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 10">Cytoplasm</location>
            <location evidence="1 10">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the ARPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005885">
        <property type="term" value="C:Arp2/3 protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042995">
        <property type="term" value="C:cell projection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1460.20:FF:000006">
        <property type="entry name" value="Arp2/3 complex 34 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1460.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007188">
        <property type="entry name" value="ARPC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034666">
        <property type="entry name" value="ARPC2/4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058:SF0">
        <property type="entry name" value="ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12058">
        <property type="entry name" value="ARP2/3 COMPLEX 34 KDA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04045">
        <property type="entry name" value="P34-Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69645">
        <property type="entry name" value="Arp2/3 complex subunits"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 10" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0568274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="386" mass="43107" checksum="188BAAABD872FDD2" modified="2022-10-12" version="1">MILLEGPSRVLQQIFQNRLKNMEKPAEVDFHLIEFDDIRFHIQASAKDPQHILLSIAVPPPPPETVFDRGLPFGALEAVKAAYGSLIQVIEPPESGFHLTIQIDVTKLAANEAERVQQMTKLASLRTVVLGAPLRVILKHLGNRTVAPDADNLVALMHRPKQSYFLIPQPEKVTVVFPMRYKDSNDVVLATSFLQEFMEARRSAGLSTAPPCLWAPTPPLELKGAPAHALDANSGFVSFVIFPRHVEGEKLDRIVWNLSTFYAYVSYHIKVRISNNFCRSLFGCKSFSCGDTQTLARAYLIMRSYNSLAIAYVITHSCEASLIRYSLSFLEVVPEVLLWSFCSSLRRSMKFNHFALCAVFKSVHAHSNEKTSEHTYSGTGESEAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEJ6</accession>
    <name>A0A8T0HEJ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BURP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G110100</name>
        <name evidence="4" type="ORF">KC19_6G110200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044816">
        <property type="entry name" value="BURP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004873">
        <property type="entry name" value="BURP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31236">
        <property type="entry name" value="BURP DOMAIN PROTEIN USPL1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31236:SF45">
        <property type="entry name" value="BURP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03181">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01045">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51277">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274491" description="BURP domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="BURP" evidence="2">
        <location>
            <begin position="98"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="323" mass="34293" checksum="95462F2D7D613A19" modified="2022-10-12" version="1">MFHCSHSMSTYNILRMLLAFLFFSALSTVGALATGRPEVTASSPDQLIREVCSPQSRLMCNNYDHNVEAISVAADEGAKAASMRDGSIVTINDLQEDFFLESSLVEGRTLTVHNNLADPAPSRVFLSAAAATTLPSLSSYNALDVMRFFGVARDSNMATSIATAAYLCGSAALPGEARSCAASTDALAAFVAAQLGNNVKVYATKGAPTSTSTSNMKAPVTIMKVAKGSVEEGRKIVVCHHLAFPSALYYCHAVTGTKVVQATLKTEGRNQPAAYIKAMAVCHLNTALWLSRHPAFKALNIAQGEEACHFLVGNDMVFTRVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG99</accession>
    <name>A0A8T0HG99_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G105400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11485" checksum="AE4D5F3B1304E33D" modified="2022-10-12" version="1">MAHSSATAHETMFPTQFLCYGLNKENKISKAKACQRGSDLKSKRKQTRISHFFKEWNSVHPQKENSAVSSTKVGTGSLSTFKTHQRAIPYDHVGCYRLPSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGI9</accession>
    <name>A0A8T0HGI9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arsenate reductase (glutathione/glutaredoxin)</fullName>
            <ecNumber evidence="2">1.20.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G185900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[glutaredoxin]-dithiol + arsenate + glutathione + H(+) = glutathionyl-S-S-[glutaredoxin] + arsenite + H2O</text>
            <dbReference type="Rhea" id="RHEA:22016"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:17668"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29242"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:48597"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:146199"/>
            <dbReference type="EC" id="1.20.4.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGI9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000037">
        <property type="entry name" value="Dual-specificity phosphatase CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828:SF38">
        <property type="entry name" value="ARSENICAL-RESISTANCE PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10828">
        <property type="entry name" value="M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="39"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00051619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0570763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="16700" checksum="2AD3BC6E226A3688" modified="2022-10-12" version="1">MESGDETRSHIQLRARAAAMAGYYSSVSYVSGQQLAGLQGSKVAVVDVRDEERAYDGHIAGSMHFSSDSFEVKLPKLIEEVKNKDTVVFHCSFSQVRGPKCARKLNEHLKNAVSEGKLEKVPSIVVLERGFNGWAASGRPVCTCQDLVCTHTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHJ8</accession>
    <name>A0A8T0HHJ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G181200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038920">
        <property type="entry name" value="At3g05675-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31060:SF37">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31060">
        <property type="entry name" value="OSJNBA0011J08.25 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="474" mass="54196" checksum="99314491B505D52A" modified="2022-10-12" version="1">MPVVQAFNTSEGKMGAGEMEVEVEEGVGVSECVTVLLVSMSTMDQGNAAKRRRLGNGCERPADEPAELLLGSIHADSSKLRECSKYFATCMSGRWANHATPREFRLEAHTEVRFYEECFGRMYFPYKAIENVGECIELLKVASQIGFAQVLDIGVKYLAAVTWSIEEEKQIRSFCDSGQISLGSKSDLRKRLHFGSNAREREEIHLKRTHRVLNGYLQLSLRPYHSHRETESRRMFEEAFQATISGLGPGKCGKILPMVLTLVTKESEKLLRSFKEVLKLREFDIFTIQITNFCWLFNTVRSSNAGQVILKQILKYKDIAPPLQKQIRKDSARLRNTPIWQFEWNSMICTIFEDILEGRLLLTTSQRLAFFKHWNGFFKIGNKPDCPLETMLVYRFILTLPHEDQEKIYHHWVSLRDDQEKKAAQYDLTEAHSLWIKHLVSQPEILAEAPECSSTGWRSEPANGESSGCETALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHW7</accession>
    <name>A0A8T0HHW7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Calmodulin-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G128900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant ACBP60 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHW7"/>
    <dbReference type="OrthoDB" id="512636at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080142">
        <property type="term" value="P:regulation of salicylic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046829">
        <property type="entry name" value="Calmod_bind_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046830">
        <property type="entry name" value="Calmod_bind_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046831">
        <property type="entry name" value="Calmodulin_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012416">
        <property type="entry name" value="CBP60"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31713">
        <property type="entry name" value="OS02G0177800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31713:SF96">
        <property type="entry name" value="OS02G0562300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20452">
        <property type="entry name" value="Calmod_bind_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20451">
        <property type="entry name" value="Calmod_bind_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07887">
        <property type="entry name" value="Calmodulin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Calmodulin binding protein-like N-terminal" evidence="9">
        <location>
            <begin position="87"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Calmodulin binding protein central" evidence="10">
        <location>
            <begin position="246"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Calmodulin binding protein C-terminal" evidence="11">
        <location>
            <begin position="317"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="394"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="647" mass="71716" checksum="BE39AFAA0F577003" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJP6</accession>
    <name>A0A8T0HJP6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G205400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="468" mass="53202" checksum="2B17AD060833F642" modified="2022-10-12" version="1">MDCALDDSDAKALGDLGAFVNVREHNSVPCFYSCEINTPSFRTARELLYFNVSIVRRRNLAIESECHNLDECTIFLVEAVNILKAIRILVACPTLTDARFSHYRWGAFSLEINVLPEFEDLMSEVFSLLKSSPSLSCFQFCNSLADASLYCKHLRTLVCENPRLETLWVSASGPNFVVLAKAIAVCLSRNTVLKSFMLPIPTLFSELNREALEILLRPLTSSSPSEANAHLKELALYLQHPGGYGVDVIANLLCRNTTLKKLDLRFSKSRSGFEDGKSSWREFCRALEVNQTLEELSCPCEVAALGDLLVPFVPDRYGRQPNTTLSTLRVFVSNKVHGRRVEVLVYNVVDVLRDLASALQRNTTLKHVQCINECITDEDFKWLYIKWYDTKCIINKNLWQGEFQIQEILRTMIDNELRINTSLESFAVGHWTLLRVGTEWQTSYRGPCLREQTRVCLAEYNVKVKMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKH6</accession>
    <name>A0A8T0HKH6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG000200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="301" mass="34435" checksum="78FD7BEC4C0A1F77" modified="2022-10-12" version="1">MQFLERVGLMFLKFGSHRGLSGVTKTTTSLVCRNLVLCLEAAEGVLEEYGESRTYCWTEGQPCASAGSTSKWRYDLGQLWGYCSCCSGILSSSCLHRRVSILYIVLARGSTPDLFLCDEPVNDDKGRPKTAITQCEKVLDLRIPEARCTLFKIREHLNHLHYYQRCRYQLRFLRSLSPFTHRWGKRGSPYEDAINLCFAETFCGGQRIRSLRPAGFTAASSSGLWSERDGCQDKRFHSRLNPEDVSSPCISRLHYIKILCHRPKVHKFTALRIANHFKGGLPKQRWLQGCCGERRINSRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNY3</accession>
    <name>A0A8T0HNY3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG100500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16295" checksum="08A69FD6DD294FE2" modified="2022-10-12" version="1">MNWYVITVNKTKTGTLAQSSLSETADQVQTTLLKESCMTPCELVVQGIALCSILLRPFPCRVLKRPITYSKKKHGQVPSVYIRYSKDTTVPPRAQEHIVKNYGPFKEIIEIDGGHFNYRPKVDDFTKLVTDLAEKYIKGAGSLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP38</accession>
    <name>A0A8T0HP38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG089300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14711" checksum="0E0E7C05FBB82A50" modified="2022-10-12" version="1">MHDEIDQSKRARMLEEVRVEYQVEMAPQGGYPSGKDPLQSSNFPPIRGNHFNAYHTLWTTQDDHDLPRISTVKLADTKDAFIQRNGGTNTEESSFISTSTEHQDSDTQSEEDDSFINFPPQHRTTQPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR46</accession>
    <name>A0A8T0HR46_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG161700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8048" checksum="53A7FFB373574DF0" modified="2022-10-12" version="1">MGGLILHVSFTVPSAQALHHIVTAKGGFKNLRRSLKILLCLDRLRRLFRPPQLQTALHMDHTSSSRGFSSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRF6</accession>
    <name>A0A8T0HRF6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG167800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRF6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36338">
        <property type="entry name" value="OS02G0495900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36338:SF1">
        <property type="entry name" value="OS02G0495900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="110"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="15685" checksum="3EE8E832583F5678" modified="2022-10-12" version="1">MSFLWEKSGTWRWAVTKGKQSKGFFLAFTSICLVSSWALGVAVMQTTNLPQPQLDEEIRKRNRADPMMMGAVNKERLGQYLGDLQRKENSEDRHSVSLPGAQERGGAGTSLSAAPSSSPSQTEKVVVSLQTGPGATESKVAVPTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRM0</accession>
    <name>A0A8T0HRM0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG178400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRM0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11718" checksum="0CDDF4FA98EC5D4D" modified="2022-10-12" version="1">MASGRKSRRTPQTWASCQKKASKSDKWCSIPMGSRSEDLGDVVADTKRTGHSSEAALTRTQDAQIRPPPCDASDEVLEEYMTSVRRKNATVTPVSTASDHPPLTNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRT6</accession>
    <name>A0A8T0HRT6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG164900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10747" checksum="76E3847FEFB06A45" modified="2022-10-12" version="1">MEWGNDGSAGAQGVGRGLAARGSPHTALGKTAEAGAPGGSSRKARPQSGKSIRDCTRRRSTKEARRWLRQKAWRWARHWKGERTSSTKSTTFSTTMSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS37</accession>
    <name>A0A8T0HS37_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG194000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9736" checksum="A13C06552CD46213" modified="2022-10-12" version="1">MIWWCGAVVARRWNHVQVFINLTIEKRCFNVEVVDVPPVMASKCDNTPERVPLDYRLHSGAPARVLKSSVDALRERDRGRFEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTD4</accession>
    <name>A0A8T0HTD4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG244300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTD4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="11"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13806" checksum="FFCE5F9DA426A294" modified="2022-10-12" version="1">MGRVLLPAKRRRRGPRFQSRVHPVPTKATRNSSSLSTPARSVVAMDDVHFERMNICRPCTAIPVSVELILFCLKFRILEFKIQFNIRGYSGNRPYRAKGTLPFCRAVLGLQLLVVVLAVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTE6</accession>
    <name>A0A8T0HTE6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG231600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751302" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="6750" checksum="598F8B756268996F" modified="2022-10-12" version="1">MFSNFSCLLHSVQFFCSTASQWLDYSKAKGGAVVTYRAPFNCHVMVGSGVFELQCSIMFVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUQ0</accession>
    <name>A0A8T0HUQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG284800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5894" checksum="D60DE0ED816E311C" modified="2022-10-12" version="1">MVYSSGGHELRISDIGAGIHRCEFPIPLYPSIPSFEVCFFKYTIICNTIRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVK0</accession>
    <name>A0A8T0HVK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="4 10">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_VG313900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="4 10"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000018">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000031">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000048">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="7 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0575054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="572" mass="63451" checksum="AF288A126D7F6D60" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVP8</accession>
    <name>A0A8T0HVP8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG324600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVP8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="172" mass="18494" checksum="36ACCE8066778306" modified="2022-10-12" version="1">MDVEAISTQTTQDEGAVTTTETIEHVDAAEDMAHDGHKEGATTEDMGPQQDVEAVELETDDDGHFRARDLHDSSDGVSAPSAEKVSSLEADEQEVVDTIATLAIEKPASDESGFAKRMAVELLSSAHDNPFTILVGCGVLHKMSGESVHCLRIEDDKFSVQVTTSLKDDHDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX47</accession>
    <name>A0A8T0HX47_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G023700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="9882" checksum="04BFE56A5AA00B8F" modified="2022-10-12" version="1">MVKIYSQQRLSQERNGIDAGSDHRPNGIVSQRVLSAKNGADAALENIILLFPPGDSVATRAVISVIIGGWLATSYVHTGAFATLSCRLQIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXK8</accession>
    <name>A0A8T0HXK8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="15">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="15">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_5G035700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14 15">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>tRNA(Ala) + L-alanine + ATP = L-alanyl-tRNA(Ala) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="15">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="15">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="15"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXK8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070143">
        <property type="term" value="P:mitochondrial alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00673">
        <property type="entry name" value="AlaRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.130:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000003">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000011">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.980.10:FF:000004">
        <property type="entry name" value="Alanine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.980.10">
        <property type="entry name" value="Threonyl-trna Synthetase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059090">
        <property type="entry name" value="ALA1_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26023">
        <property type="entry name" value="ALA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="ThrRS/AlaRS common domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 15" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 15" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 15" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="7 15" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Alanyl-transfer RNA synthetases family profile" evidence="18">
        <location>
            <begin position="98"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="885"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="683"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="802"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="806"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00055137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0575860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1041" mass="113087" checksum="9881F18D718AEB4F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY17</accession>
    <name>A0A8T0HY17_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G012400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035772057" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5840" checksum="5287E9C4A1C95AFC" modified="2022-10-12" version="1">MGPNARLGLSLWTTWKCLIRSSVVLTSVASCRCITSFVCKAECIILASRQSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I068</accession>
    <name>A0A8T0I068_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="8">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G111000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Extracellular space</location>
            <location evidence="8">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="8"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I068"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02176">
        <property type="entry name" value="GH16_XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000025">
        <property type="entry name" value="Xyloglucan endotransglucosylase/hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008263">
        <property type="entry name" value="GH16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01034">
        <property type="entry name" value="GH16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0052">Apoplast</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GH16" evidence="9">
        <location>
            <begin position="29"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="7">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0576830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="296" mass="33160" checksum="4E9517B8A309AD44" modified="2022-10-12" version="1">MGFVGLQAGVQLATVAALSLAMVGMVYSATFTEQFTAFSHDGIHVQVAPDGQEAKIVLDEYAASGFGSKNQYLFGNITMMIKLVPGDSAGTVTAYYLSSAQPNHDELDFEFLGNTSGQPYILQTNVFANGIGRREQRINLWFDPTTDFHNYGVLWNRNQIIFTVDNKPIRVFKNNEDLGIAYPKNKPMGLYASLWNGDSWATQGGMVKTNWTHAPFIVSFKDFTTLDGCVVANNDISPCTATTTHWWEASAYQTIDRKQAEQILWVKNNYEVYDYCTDRKRFPVAPLECERNIPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I124</accession>
    <name>A0A8T0I124_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G090300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I124"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8724" checksum="9045B1EE6ADE1959" modified="2022-10-12" version="1">MLGLKSKKVVGSAPCTCQCNLLLKLPSRQLILIILVESPVAILTTRSSELHAPPATQYTRVDSGLPQQNMYRRFKDTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1M8</accession>
    <name>A0A8T0I1M8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G118700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1M8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11898" checksum="C32FCE6E98EC4F77" modified="2022-10-12" version="1">MAYCMPIFWPNSIYTVSEFKYIYHGKELAIREARWPLPTRVPSRLSACFVLQLCVQCPTSCALESMFKLPSFRITVFEEDQVAVPPAVVRVTGWYRFELLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5U1</accession>
    <name>A0A8T0I5U1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Glycosyltransferases</fullName>
            <ecNumber evidence="15">2.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_4G018600</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Golgi apparatus membrane</location>
            <topology evidence="1 15">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the glycosyltransferase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="15"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5U1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015018">
        <property type="term" value="F:galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042285">
        <property type="term" value="F:xylosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010417">
        <property type="term" value="P:glucuronoxylan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009834">
        <property type="term" value="P:plant-type secondary cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00218">
        <property type="entry name" value="GlcAT-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000064">
        <property type="entry name" value="Glycosyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005027">
        <property type="entry name" value="Glyco_trans_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10896:SF65">
        <property type="entry name" value="GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10896">
        <property type="entry name" value="GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03360">
        <property type="entry name" value="Glyco_transf_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 15" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="9 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="12">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with galactose moiety of substrate glycoprotein" evidence="14">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605027-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR605027-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR605027-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU363127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0578379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="422" mass="47710" checksum="53D5E82B07DD256A" modified="2022-10-12" version="1">MASLRRSLSPQIRDCRASSSGKSEHNPFQQLNASVPASLGARALSQAQSLLLWPLRVFAMAESFGRGATKMSSWKKLLIQFGVCFVIGLFLGWFTPPKWQLFVPDSLAVEGKTAEADLFGSSRVANALTETKTASSLGSQAREVISVDEVSGFRASLEVPLEPRKLLIVVTPTYTRPFKAYYLTRLAHTLKLVPPPLLWIVVEMHAQSLETAALLRETGIMYRHLVCDKNLTNVKDRGTYQRNTAMAHIEEHQLDGIVYFADDDNMYTLELFEQMRTIKRFGTWLVGMLAPGKSRPILEGPVCKDEKVVGWHTNEKSKRLRRFHVDMSGFAFNSTILWDPRRWKRPTLEPIRQLDTIKEGFQETTFIEQLVPDESVMEGRPPGCLKVMVWHLHLEAPKGFAYPAGWTLTTPLQANIPLRRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I699</accession>
    <name>A0A8T0I699_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G006700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I699"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12663" checksum="D51FF43B52511EC5" modified="2022-10-12" version="1">MCERVWIQSELRTHTSVSIFMCVLPAPVIFRSFSFCNENLQPSTVQTFKITFLEIMSRLYITICLDFFYLSPWLETCSVAAMICSTLCLADLFVISFHLGLHFIIHVER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6L2</accession>
    <name>A0A8T0I6L2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G037200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6L2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12492" checksum="98226A42554B4367" modified="2022-10-12" version="1">MITSSLWLEPSPSPERPQHGTSRMDLKLHHKLSMSLQTWTANQHAQVASFASRRSDEQIISRARGRREAHGLQLLPSSAPHEKREPASISPQSWAAPAGRAVNIHLHLPRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I728</accession>
    <name>A0A8T0I728_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ZZ-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G089800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Autophagosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I728"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005776">
        <property type="term" value="C:autophagosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031410">
        <property type="term" value="C:cytoplasmic vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14319">
        <property type="entry name" value="UBA_NBR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000199">
        <property type="entry name" value="next to BRCA1 gene 1 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="Nbr1_FW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056893">
        <property type="entry name" value="UBA_Nbr1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930">
        <property type="entry name" value="OVARIAN CARCINOMA ANTIGEN CA125-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20930:SF0">
        <property type="entry name" value="PROTEIN ILRUN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24932">
        <property type="entry name" value="UBA_NBR1_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PB1" evidence="10">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="9">
        <location>
            <begin position="285"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="8">
        <location>
            <begin position="685"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="91"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0579314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="782" mass="85662" checksum="2ABA7DD036F625F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7B4</accession>
    <name>A0A8T0I7B4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G019100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7B4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="92"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="481" mass="55618" checksum="7271701C3A770D22" modified="2022-10-12" version="1">MVVGSSKIVLPLPIIQVPHSLKDVLDEFLGDTVEAPGLRSVTEFAAHQDENDCTPCDGEHHVGAERRQGSTAVETQLICKRSCPEHKEVMSPALWGALPKDLLQIVFAHLPLADSSRLRCLSEEWRDSIETPHSEFIQVCKAVISTHTNSFALISTDKDDMYGVFWVRVFDMKANRWHEFEFDSEKKYCVALVACDGGLVCLLSVVPDVEEEENEDEYDLPKPLLLTVWNPLTGEKYELPCLDHLDGLCPTMLQLVVDPQTMHYKVMVATKDIYEPKIDQQGAYIYDSQSDRWSQAEKSSRVMFGKYYSWPNTNMWSTETVVTRPCVFDFATSRLHTVKVKRQVEPWGRQNLLRPYAITAQDRLFVLDKFITDESFVEVFRILEYHADVNQSGRTNWLFKRVHSCGPFESAPRYSQDRVRLFALKEFLLVCVDSSFRHRKPRLWLYNVCTLEWRELPSLVKYKDIGQDDIMCELRPWYLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7D7</accession>
    <name>A0A8T0I7D7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G096600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7D7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="549" mass="60728" checksum="43FC5EF417A42923" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8V1</accession>
    <name>A0A8T0I8V1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Vacuolar cation/proton exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G142700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Vacuolar cation/proton exchanger (CAX). Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8V1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009705">
        <property type="term" value="C:plant-type vacuole membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015369">
        <property type="term" value="F:calcium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006874">
        <property type="term" value="P:intracellular calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000008">
        <property type="entry name" value="Vacuolar cation/proton exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1420.30:FF:000012">
        <property type="entry name" value="Vacuolar cation/proton exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="entry name" value="NCX, central ion-binding region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004713">
        <property type="entry name" value="CaH_exchang"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004798">
        <property type="entry name" value="CAX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00846">
        <property type="entry name" value="caca2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00378">
        <property type="entry name" value="cax"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31503:SF22">
        <property type="entry name" value="VACUOLAR CALCIUM ION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 12" id="KW-0050">Antiport</keyword>
    <keyword evidence="8 12" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 12" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="10 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 12" id="KW-0813">Transport</keyword>
    <keyword evidence="5 12" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="331"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="13">
        <location>
            <begin position="84"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Sodium/calcium exchanger membrane region" evidence="13">
        <location>
            <begin position="267"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0580034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="423" mass="45820" checksum="E9844D3BF3438915" modified="2022-10-12" version="1">MYTHSRLIGGVVCCTTLTSMKNGECYDKTMANLAPSLPTLCLPNVWERFVVSAKQVLFGTVLNVLLVAVPMALLSNYLHIGNSWVFILSLIGIVPLAERLGFITEQLAYFTGPTVGGLLNATFGNATEMIICVFALQNNMVRVVQLSLLGSILSNMLLVLGCAFLSGGIANSMKEQKFDKAGAHLNSSLLLMAVMCVLFPAALHATRTEIHLGESELMLSRVISGIMLVAYAGYIYFQLCNPPLREEDIEAVENGESEECQVDAWSAIFWLAVLTVFISILSKYIVDAIEGASEAWQIPVAFISVIILPIVGNAAEHTSAIIFAVKDNLDLSLAVAIGSSTQISMLVIPVGVLLGWPMGVNMDLNFELFETAVLFISTIVVAFMLLEGTANYFKGVMLVLCYFVVGASFFAHVDPPVHHVHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9X2</accession>
    <name>A0A8T0I9X2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G119200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9X2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="336"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="473" mass="53317" checksum="83E016D75CE17518" modified="2022-10-12" version="1">MASKRRREVGEEGEQEEVESLEEELRRERRKSWEVLGKRKVVGEAGDAVDVRPVGIFLRGTSTELVSYSKPMPFDKVLEELSIIRDCKSGVIFKRGSNRSMAGEVVLPFGEYDFLPSSLSLCDNARCLPMEGSTSSPPNLTNVNNLEKSPQCGPQPIPAWNRGVYPFVGNMPMLPMLGWGRGPSMPPLPHQANLPKFSMEHQSNPPKFTVEHQVNLPKFTLDHQAKPPKQTVEHPPNPPKQTAELQLNLQKQTAELQPNLSNHTVEHQLNPAVQMVDHQPKLTVETDEGMYARLLRNEGSPLLSKYEPRQTRKRKQKISLEDLTPDQIQEVKQGGHWKDHWVVHLIRIRGELANVFAAPPKQGVDNWGRLHRALITNCPDFNKDSEACRKKWAAIYKDYKHDKAANSTSGSVRSDKCKWYVLVDQYFFDRVNVGAQDDSAHESEGIPPTSTVSEVTLEVSPKSSKGVFLEMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAG7</accession>
    <name>A0A8T0IAG7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G101000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14540" checksum="7ABCEA3E095844F8" modified="2022-10-12" version="1">MLNPGLLRTNCSERGPPIQTTAPLLLNLKPRARTTTTSSNSSKNTRAHIQSHYRAPNSQPQRQGTSQSQFQEDRQLQTHKTPPHQHAFRQHSTHLAEHPTAFPKHHTKLQTHGNITATKHSRKQRLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB26</accession>
    <name>A0A8T0IB26_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G118100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB26"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="2"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="444" mass="51097" checksum="62367B9F8DE09C02" modified="2022-10-12" version="1">MEAVWRRLPEQLVDCVLSFLPVPALFRCRSVCRRWNRLLRKPSFLELCDRNARNKMYLFVMHHVNMAGFMGNLLNGTYRKWTCVLDLEEGRWYKIPVNGSVVTPSRNIPRRLAMNDGLICELSQLPDSPVKYSLVVFDPVANMRWPLPVRSRQEDSDFPIVVLGVDGDCRLRRAFNVFVMDQNSIFMNKPSGFFVYESFTNAWRALKNPPLELGYGVGESTGRRLEESAVFFQGNLYMTFWYYNVRYPRIVILSYNLEKDLWSEVYAVKSKNPGNPQLIVDGTRLFLSAWVDALRPEGLGFPQSMFNYSELQVTEILVQRNSSRTVMNVTKDEVKQICGKSQTGLLRGLPLLCNNDISFAFPPIPNEDRFLVMVSDSTGAVIFYDMLDDTVKKFPAHPSHSLHQRFFKREKAQILQDGVVEEEDISSSFSAKLITLSMRSILSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICG0</accession>
    <name>A0A8T0ICG0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G250900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11995" checksum="084B0B1FC3BF713E" modified="2022-10-12" version="1">MARKKERRERARKMMSQPTSACTEDLHTCRNIRDWIGETSIRQSSADWLGERAMERERAFWQGDQTRTMRRFAAGSVGTDVDDFARNITEIARAAASLFGSCYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID33</accession>
    <name>A0A8T0ID33_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G202900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID33"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.100:FF:000001">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="entry name" value="Ribosomal RNA adenine dimethylase-like, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF27">
        <property type="entry name" value="RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="8">
        <location>
            <begin position="71"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="36547" checksum="F9F854A5797CCBCA" modified="2022-10-12" version="1">MALCVGICSPAHVSAGAFSYRGGGCQASRLRVLCAVQSREENVRSTMKALKSQNHRPKKWLGQHYMVNEQVNIDMVKAAEIQPGDLVLEIGPGTGSLTNALVDAGANIIAVEKDPGMAVLVGERFGHTGQVEVIKEDFVKWPVVSYMQQALEKRSGASDPPRRAKVIANLPFNITTQVVKQLLPLGSTFSHIILLLQDEAAIRLVDASPDCEEYRPISLLINFFSVPEYKFRVERDNFFPQPNVDAGVVSFALKQESEYPRVSSTKSFFTLVNSAFNGKRKMLRKSLQHLHTPATTQAALTSIGLLGTARPEELTLDQFVALHNALTQQTTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFH9</accession>
    <name>A0A8T0IFH9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Post-GPI attachment to proteins factor 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G006300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the lipid remodeling steps of GPI-anchor maturation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Golgi apparatus membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PGAP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFH9"/>
    <dbReference type="OrthoDB" id="419770at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007217">
        <property type="entry name" value="Per1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148">
        <property type="entry name" value="PER1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13148:SF0">
        <property type="entry name" value="POST-GPI ATTACHMENT TO PROTEINS FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04080">
        <property type="entry name" value="Per1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="2 7" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036511320" description="Post-GPI attachment to proteins factor 3" evidence="7">
        <location>
            <begin position="23"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="365" mass="42085" checksum="0EBF7FD2663C30A6" modified="2022-10-12" version="1">MRLRRSLLLVVLVSSLVFVCEGSEGDERPRYRACVQGCEQTGCVDGQCYNSCHFPVNVDLEGNILPKKALNSPHEKFLEEPLYLRWKKWDCISECRYQCMLREEVAREAGPEDPVKYHGKWPFIRIYSLQEPASVAFSVLNLLVHFQGFSSFLVLMYYKLPSRAKGPYYEYVGLWTIFGLLSMNSWIWSTVFHSRDMTFTEMLDYSSAIALIGFSLMLAIIRTGNLRAEAPRVMVAAPIIAFISTHILYLNLYKFDYGLNMIVCVVIGVAQLLIWATWGFVTKHPARFKLWSVVFGTAFAMLLEVFDFPPVWGIFDAHAIWHASTLPITYLWWSFIKDDATYRTEMLVKKSKASDFQSEDTRKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHJ7</accession>
    <name>A0A8T0IHJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G048600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10290" checksum="AD01D0C007C97DFE" modified="2022-10-12" version="1">MPVKRMQMFHTNDSPSLHLHPSTPSPRDVHIKPRRPSPQNLHRAGASLVPTNFSASVRDSIVTSTNIRGKLLEMHTPYSKDQKSISPAMPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHL4</accession>
    <name>A0A8T0IHL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G120200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="138" mass="15872" checksum="D8C3AD864E35B877" modified="2022-10-12" version="1">MDLLRLRFLDIAALDLANCTCLPSMQVRSVLVVWSFVFLSWMGSPGVVCRGFGVLEWFRDWRNGVWCWFERGRGFLVADWSGFSGWLAREGLRGRTVCCSDLEGQRCGVGELVCFGRVRWSILFLAALFVWFGFFNLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHL7</accession>
    <name>A0A8T0IHL7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G029700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="35"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="45101" checksum="722E94B5750CA392" modified="2022-10-12" version="1">MWKVLPTHLPLYSKQCTLLPTKAVTPLWEADVMDPEIWSELPDHIIYKILALLPLRDFLRLRWACRRWSRLIESPVFLDEFSQAKVERPWFAIVAEARKVYVYQPHSEKWYNMPASFLQPNSIFLATSKGLILSRFSRRASGLHDLLVVSNPFTGSQRILPRQILVGCGYAMVVDEATKAYTVYHFGQLEPFLDGLVANPHDHTLEAFSSTTNSWQVLCRINHDIFAGLPSYAFDDTKLLVWDDYIICRLRGYFGVFAYSLTRRDWLQIPWAVRPSICAFQQLLCSRDSLVMVVGIKKNMAADSGCESIHVHQLPRGTLDWSEVAVVPEYMNVMRYNFDSYGLGDFIFMLFAAKLLVFDTTYGTWSFAPHCDHICKNLQEFCFEPRLNTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHQ9</accession>
    <name>A0A8T0IHQ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Staygreen protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G060800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the staygreen family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHQ9"/>
    <dbReference type="OrthoDB" id="1931912at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024438">
        <property type="entry name" value="Staygreen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750:SF4">
        <property type="entry name" value="LP06106P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750">
        <property type="entry name" value="PROTEIN STAY-GREEN 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12638">
        <property type="entry name" value="Staygreen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Staygreen protein" evidence="6">
        <location>
            <begin position="87"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="281" mass="31213" checksum="7AC205250D749E20" modified="2022-10-12" version="1">MAVSISQCGVRVALISSALRRGDSCVATVASCQGCRELSLNVVDCAGLQQRRGKAVTSGRESAPRCRKQQQLKRFAVVARLFNPGDFDPSKLTVRFEDNANDIKVKSVEDLLPRNYTLTHSDVTGELLLTIGPSFNRQQLTEWYTRLMRDEIVAEWRGSEQVSLHVHCHVSGGHVLLAPAALRNSIFEREMPLVLEAIRYGDKDFLAEYPELHASTVWVHFHSSDPAYNRADCWGPLFYAASPIRRVTGKSVPSCISEPFTPLTLVKVQKDPAEVCSVMSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIU9</accession>
    <name>A0A8T0IIU9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Condensin complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G096800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the CND2 (condensin subunit 2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022816">
        <property type="entry name" value="Condensin_barren_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13108:SF9">
        <property type="entry name" value="CONDENSIN COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05786">
        <property type="entry name" value="Cnd2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017126">
        <property type="entry name" value="Condensin_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0226">DNA condensation</keyword>
    <keyword evidence="8 11" id="KW-0498">Mitosis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="153"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="431"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="431"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR017126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0582945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="690" mass="76085" checksum="7BCC3BB1B736221C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJI1</accession>
    <name>A0A8T0IJI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G137000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0583452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="7109" checksum="0DF33A326E256453" modified="2022-10-12" version="1">MCACGTPVAAVYVDHAPGNIRLSECAQCGYAADEYVECEMMTVKLLQNQIIAWLRSLAGQVESNDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILT2</accession>
    <name>A0A8T0ILT2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">26S proteasome non-ATPase regulatory subunit 1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G144900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the proteasome subunit S1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILT2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034515">
        <property type="term" value="C:proteasome storage granule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042176">
        <property type="term" value="P:regulation of protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000048">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016642">
        <property type="entry name" value="26S_Psome_Rpn2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002015">
        <property type="entry name" value="Proteasome/cyclosome_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048570">
        <property type="entry name" value="PSMD1_RPN2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040623">
        <property type="entry name" value="RPN2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10943:SF2">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13646">
        <property type="entry name" value="HEAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01851">
        <property type="entry name" value="PC_rep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18004">
        <property type="entry name" value="RPN2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21505">
        <property type="entry name" value="RPN2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015947">
        <property type="entry name" value="26S_Psome_Rpn2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="2" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0832">Ubl conjugation</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="800"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome non-ATPase regulatory subunit 1/RPN2 N-terminal" evidence="14">
        <location>
            <begin position="6"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="26S proteasome regulatory subunit RPN2 C-terminal" evidence="13">
        <location>
            <begin position="816"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="868"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="993"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="911"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1008"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1028"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00057191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR015947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0583538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1038" mass="111694" checksum="939CABB7C3AC9197" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILZ3</accession>
    <name>A0A8T0ILZ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G173300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILZ3"/>
    <dbReference type="OrthoDB" id="551907at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314:SF188">
        <property type="entry name" value="TRANSCRIPTION FACTOR KAN2 ISOFORM X1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="71"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="131"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="164"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0583939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="377" mass="42004" checksum="69D7C8E59C9360E4" modified="2022-10-12" version="1">MQGENENEAGRGCTPGEGSSPDRRCTLSADGMPGCSTVLFDSPNKSTATCRSAPPSLGARSGDGKTRRYLRSSEPRLKWTEELHQCFMRATAKLGGPEKATPKAILQEMNVRWLKIAHVKSHLQMYRNPKSGKSYNPRSDFSFQQAEESSEVWNSHAMDKDYQVSNSTQMQQPGSRHLMQESDSLEASWRSSQTRGSAVQHPIVTNVDVTTTAREHVYLASPAQINQIGQFGNVISQTSDHGDESRVGADFFKMAEVLLESRTNKSRDFETSDDVDIDRRQFLSDQILAGDADTARLYDSAEALAHNLLMAMRERKLLESRITQSSIGPHETHYDLAIIPEVPLDLTMSVGVPDRNPNVRSEILTLDLTEQLNRPHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INJ8</accession>
    <name>A0A8T0INJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein BYPASS-related</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G218500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ROH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INJ8"/>
    <dbReference type="OrthoDB" id="1878996at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008511">
        <property type="entry name" value="ROH1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31509">
        <property type="entry name" value="BPS1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05633">
        <property type="entry name" value="ROH1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035716641" description="Protein BYPASS-related" evidence="7">
        <location>
            <begin position="19"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="146"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0584567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="40667" checksum="58A46E0190FB3D80" modified="2022-10-12" version="1">MAQHGGASLLASLGAVLNLHFSLHRGGNTNNVASKRHPVLQEFETRLRDRLETLKVAGEEKSFLSIDWLLQAMSIVLATHANVEALIPESQLSLSMHRDDKWVDEYLDDSAKLLDVCNILKEGISEVEHYQMLVQFALHNLDNREISGAELKYSRARNALAECKEAIKRKDTEYRQGFPKSKLENCSSMLRTMGDKLVTPKGEEAMKGNGFLNAIYGAKVTTIFLCGLLVTALACKPKRPLTNLSVASHYKWSPALVSLQQRVKEETDKRKTKGSIALLRELDSVDASVQRLHEILDRHLTEKAFPLAREQATELKMEVEALRKHSADLGYGLQPLEVQVNELFRMLIASRLALLDIISSART</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRU9</accession>
    <name>A0A8T0IRU9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G040000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10011" checksum="88B09B768A77F25A" modified="2022-10-12" version="1">MRCIVVPHVLQMHMVVVLMGNVLFIGSGSRVFGSSNLRDGGMRASDTGFRGTHLFTGSAFHMEDGGNVWDFAVVCAGLADGEDVVKERPADSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITE8</accession>
    <name>A0A8T0ITE8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G090200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015377">
        <property type="term" value="F:chloride:monoatomic cation symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1740.10:FF:000091">
        <property type="entry name" value="Amino acid permease family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004841">
        <property type="entry name" value="AA-permease/SLC12A_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018491">
        <property type="entry name" value="SLC12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004842">
        <property type="entry name" value="SLC12A_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827:SF72">
        <property type="entry name" value="GH08340P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11827">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00324">
        <property type="entry name" value="AA_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03522">
        <property type="entry name" value="SLC12"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="431"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid permease/ SLC12A" evidence="7">
        <location>
            <begin position="82"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="8">
        <location>
            <begin position="568"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="SLC12A transporter C-terminal" evidence="8">
        <location>
            <begin position="692"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="844"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="885"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="847"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="920"/>
            <end position="936"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0586432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1044" mass="114523" checksum="84FB78553B944627" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITV8</accession>
    <name>A0A8T0ITV8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G102400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043377">
        <property type="entry name" value="GSTT1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44750">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE T1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44750:SF1">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE T1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="8"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="96"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="28420" checksum="B7B1E25D40492242" modified="2022-10-12" version="1">MANHEDSSGLKLYVHQGSQPARAITIFCRANHIEAEEIKVDILQLESRTAEYKKKINPMGLIPCIDDNGFKLYESHAILRYLATTRNVADHWYPKDPKQRALVDAALDWHHLNLRRYAAQLVISRVLWKLPGHAGFFPDTDHDALSAESVKMLPRVFDQLEFMLQHGKFLQNANELSIADLSLACELAHLQLLGKEGQESLLGCRERINKWLADVEEAASPYFKDVHEEVIVPYAKHVEEIRAQGHLGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITY6</accession>
    <name>A0A8T0ITY6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G146000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11340" checksum="CCB97173950B5C8D" modified="2022-10-12" version="1">METAIPDSPLNQDSHQRCEHYLTTSDKFDRHSNGINRHLTALPPISQTALKPTQTKLHISNFIKDLAQTFQFLQLGTVSEVTSRIMLGRFRLAGVTPKPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUC4</accession>
    <name>A0A8T0IUC4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein arginine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G157100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.150:FF:000016">
        <property type="entry name" value="Protein arginine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000003">
        <property type="entry name" value="Protein arginine N-methyltransferase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000029">
        <property type="entry name" value="Protein arginine N-methyltransferase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.150">
        <property type="entry name" value="Divalent-metal-dependent TIM barrel enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007857">
        <property type="entry name" value="Arg_MeTrfase_PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035075">
        <property type="entry name" value="PRMT5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035248">
        <property type="entry name" value="PRMT5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035247">
        <property type="entry name" value="PRMT5_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10738:SF0">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05185">
        <property type="entry name" value="PRMT5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17286">
        <property type="entry name" value="PRMT5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17285">
        <property type="entry name" value="PRMT5_TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015894">
        <property type="entry name" value="Skb1_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRMT5 TIM barrel" evidence="13">
        <location>
            <begin position="38"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 arginine-N-methyltransferase" evidence="12">
        <location>
            <begin position="320"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="PRMT5 oligomerisation" evidence="14">
        <location>
            <begin position="489"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="280"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="466"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="357"/>
            <end position="358"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="441"/>
            <end position="442"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for specifying symmetric addition of methyl groups" evidence="9">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR015894-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF17286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0587334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="658" mass="73226" checksum="F3652026AA3986E8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV75</accession>
    <name>A0A8T0IV75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HMG box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G102300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22005">
        <property type="entry name" value="HMG-box_AtHMGB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47658">
        <property type="entry name" value="HIGH MOBILITY GROUP B PROTEIN 12-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47658:SF1">
        <property type="entry name" value="MEIOSIS INITIATOR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="223"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="223"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="172"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="291"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0586591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="35003" checksum="D05EF16A4BBCD037" modified="2022-10-12" version="1">MSGAHVWEGRLWAGSPSRPAQLCQRGFPRPRLDEFEAERVSKVRALPPVSPCFGPQSLLSSLTCLSSCWFSLPLSLSCAVPIFAFFVLETLKEASLVIRVVKMAKAAAITQANPQNALKRVSVDPSDLKRSASGSGFTRCGKCDTDIAVARVESHDCEQERKTKALISKMTKQAVKKNDDSAKMAKHAVKKGDDSTKGTKRKTDPKAAVKKTKKAKGKDPNAPKRPASGFFVFMETFRKEYKDANPNAKGVAVVGKAGGEKWKQMSEEEKAVYNKEAESRKATYDQAMIDYKNKDSKDDGEVSEDAAEDDDEEADVEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVF6</accession>
    <name>A0A8T0IVF6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G129200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="8">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVF6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112:SF44">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="51"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0586939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="15227" checksum="8A7839E8DBCE593D" modified="2022-10-12" version="1">MAASALGVISVPSSGVASSLLSNTKPSSKLVLTRSFRTRAGRARTAITAAYQVTLITPEGDKVVHVSKDECILDAAEKQGVVLPHNCRSGACSSCVGLLKSGTVNQDDQTFLDEAQLEAGFALMCTAYPTSDCVIETHKEDQFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVU4</accession>
    <name>A0A8T0IVU4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Peroxidase</fullName>
            <ecNumber evidence="20">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_2G195000</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="17 20">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="17 20">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 20">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="20"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31235">
        <property type="entry name" value="PEROXIDASE 25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17 20" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 20" id="KW-0349">Heme</keyword>
    <keyword evidence="20" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="12 17 20" id="KW-0408">Iron</keyword>
    <keyword evidence="8 17 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 20" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035960822" description="Peroxidase" evidence="20">
        <location>
            <begin position="27"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="21">
        <location>
            <begin position="29"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="18">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="39"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="76"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="125"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="204"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
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    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0587834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35728" checksum="D002B66232F93956" modified="2022-10-12" version="1">MVNARVSFCFVALVVVAVLSCHGVESAVPLQVGYYSNSCPDAETIVLQTLQTLIDADPEEGPGIPATLLRLHFHDCFVRGCDASVLLDVPKSEKTAPPNARLLGFEAVDAIKSALEEKCPGVVSCADILAFAARDSVSITLGPNYAVPAGRRDGNVSMADDASKFLPDAQSNVTQLVANFANQGLSKEEMVILSGAHTIGDAACHHVDSRIYNYPSKDGVDPNIPADYAKKLKKKCRDRGLKTRTFDLDFTTDLQFDTEYYNNLAVKKGMLVSDQALYTDASTRVMVEKYRKTAAFFDAFAKAMVKMGNIRVLTDTDGQIRTNCRAVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW53</accession>
    <name>A0A8T0IW53_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G126500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW53"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="31" mass="3502" checksum="5DA2ED2702485118" modified="2022-10-12" version="1">MVLVPCSWFKCAGIRAQGTKTGKQMTESEWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX14</accession>
    <name>A0A8T0IX14_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G230800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12003" checksum="E338B07BE095655F" modified="2022-10-12" version="1">MRFLLIVANTPGPPVYTTLEQFGFRVFIFDGFSTSYCVTFSSGLHSFVSNIFNMSVNLRRHEQFLCDSYRPCLVRYMLLPAPSCEGELFSLGFGVGWAPRGAAQKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J081</accession>
    <name>A0A8T0J081_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G232300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J081"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13231" checksum="30412ACDECBF2ABB" modified="2022-10-12" version="1">MARTSLRLEFERAAHFDICSSLWIVGLLECFVLDLCAGIWSLLASLFCRCSSLFYIFSPLPIFCCFHFLSSSSLSSSHYLIPSLHSLTSAFSLLLSPSFISALLLPLFFCGLTPFTNGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1C0</accession>
    <name>A0A8T0J1C0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Superkiller viralicidic activity 2-like 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G284600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1C0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13154">
        <property type="entry name" value="KOW_Mtr4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000006">
        <property type="entry name" value="DExH-box ATP-dependent RNA helicase DExH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000001">
        <property type="entry name" value="Mtr4 exosome RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF7">
        <property type="entry name" value="EXOSOME RNA HELICASE MTR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="95"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="344"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="304"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1021" mass="113926" checksum="20A8F813C4C2474B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1F4</accession>
    <name>A0A8T0J1F4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_1G047200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1F4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07991">
        <property type="entry name" value="LPLAT_LPCAT1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045252">
        <property type="entry name" value="LPCAT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063:SF56">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23063">
        <property type="entry name" value="PHOSPHOLIPID ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00450">
        <property type="entry name" value="RECOVERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="387"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="424"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="15">
        <location>
            <begin position="460"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0589774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="517" mass="58405" checksum="5B2F820DB73EBD21" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2B9</accession>
    <name>A0A8T0J2B9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G009500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2B9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035745901" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="67" mass="7803" checksum="A8E8F4524F4096D7" modified="2022-10-12" version="1">MRAHCCLKFLLQCCLCCLVEWDSRSFGRSWEVRVRNSDGDAWGEVFVIFGCCRYFQLVNLEGGSESW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4T1</accession>
    <name>A0A8T0J4T1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G135800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant rapid alkalinization factor (RALF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4T1"/>
    <dbReference type="OrthoDB" id="1613518at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005179">
        <property type="term" value="F:hormone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008801">
        <property type="entry name" value="RALF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33136:SF6">
        <property type="entry name" value="PROTEIN RALF-LIKE 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33136">
        <property type="entry name" value="RAPID ALKALINIZATION FACTOR-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05498">
        <property type="entry name" value="RALF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0372">Hormone</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0590920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11297" checksum="E8123770015F3EA1" modified="2022-10-12" version="1">MATSSIRTAVVMMVVLFMGMLVVSTQGQIAMAPAPTPEAFFPGMAPFESPTFNPTGAPTFISYAALSANRAPCPSGTGRSYYTPGCTAQPSATPYSRGCYQITRCARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6X5</accession>
    <name>A0A8T0J6X5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G122200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6X5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042793">
        <property type="term" value="P:plastid transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045893">
        <property type="term" value="P:positive regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090228">
        <property type="term" value="P:positive regulation of red or far-red light signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034581">
        <property type="entry name" value="PTAC12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35720">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35720:SF1">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 12, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="131"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="161"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="592" mass="67181" checksum="C4AD07C9900FA1C5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J778</accession>
    <name>A0A8T0J778_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G146700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J778"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="261"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="726"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="726"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="751" mass="82807" checksum="729A8DD4B91D171D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7J6</accession>
    <name>A0A8T0J7J6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G189600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7J6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="353" mass="40016" checksum="6980D915F66B5FD1" modified="2022-10-12" version="1">MYKQMPKCDEFLIWILMVSISPIAIIVLIVLALLNMLQFFFKAALLFSIVSIHTPFAVLNIMSSLLFYKLVNLYDPSTDTAARMGMDDPRSSVGIEIQVLVSDFFKVIAAELLLVLSTGVITFYTAPRQVFYASMAVGVAAILMKWLNTHSLSKTAFSCLCDGYGLNPLMFFFSFIGLFDIGCHPVAKCSFVASKAFLFTNENPKLFNGEVTESENMSIKFDQWDAFEEGLFELGLFELYPRIDFITRNIRNHRKYILKSSMVLKSFGVDICDYPVERLELPEDYGKRNELLNFLLTLAEDDGFVTDKMRGRYENSLTLLEIVGGVGQHNGYRTVQPEESQFVVAGSTNHKYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8W7</accession>
    <name>A0A8T0J8W7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G245800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8W7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015123">
        <property type="term" value="F:acetate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051633">
        <property type="entry name" value="AceTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047622">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31123:SF1">
        <property type="entry name" value="ACCUMULATION OF DYADS PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01114">
        <property type="entry name" value="GPR1_FUN34_YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0592364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="230" mass="24845" checksum="FA49CE3A07FC72AB" modified="2022-10-12" version="1">MAVEHGYNGDGHHLEDGPMKPPPHVAAPAVVRIANPAPLGLCGFALTTFVLSCYNAAIFGISVSTPPNVVVGLALFYGGTAQLLAGMWEFKTGNTFGATAFSSYGAFWLSWAVIQLPGFGVKAAYTSTGYQHDFINAIAIYLLAWTIFTFMMWLATLRSNIALSTLFAFLTVTFLLLTISDFRNSHGFKRAGGFMGIFTAIIAWYIALAGILTHENSYFVLPVGNLAKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9H5</accession>
    <name>A0A8T0J9H5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G187800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AP2/ERF transcription factor family. AP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9H5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000004">
        <property type="entry name" value="AP2-like ethylene-responsive transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF81">
        <property type="entry name" value="OS06G0145700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="69"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="171"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="63"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00037973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="389" mass="43752" checksum="C3A05D3A4A2D67F1" modified="2022-10-12" version="1">MKSSSSEDGLQTHGNATSLFGNTIPVGRRTPMKRTPRCPPKPSLSSKTSEQRDAMEAAASSSVRKKSSKYKGVTKHRVTQRYEAHLWDKSAYNAKQKKKGRQVYLGAYDEEKAAARAYDLAALKYWGPSTVINFKLEHYIQELKEMEQISKEEYLTTLRRKSNGFSRGISKYRGVARHHHNGRWEARIGRVEGNKYLYLGTFGTQEEAAEAYDRAAIHYRKAAAVTNFELSRYPDLCDLYQNVPAKKGPKNKIIIKNCPKDNQTAEGVGSSSEMKVVENENQTADGGGQISITFTNLSDGGMNLTCPQDSLRFPSDFEMAVVELPKHVPSPTLEARGLNNNVPKKVKQEDFSSVPKNISQPHYFEDLGAEYDDILTCFNVFNDMSYTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA60</accession>
    <name>A0A8T0JA60_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G269300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA60"/>
    <dbReference type="OrthoDB" id="4233498at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035878843" evidence="1">
        <location>
            <begin position="30"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="13571" checksum="97B679992A0ED5AF" modified="2022-10-12" version="1">METVRNMILSGAVAMVLLLLLGPTPGTNALTSPVCETSAASGLTSDCTNVGFFLKSLGDTPCGNGNGVASKCTNMKTIGTCTAAICGDVASQPCSTVADYVNTLSTNCASTINGNSHSGGTQIMNENGGLKVEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAK5</accession>
    <name>A0A8T0JAK5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hexosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G215400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAK5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02537">
        <property type="entry name" value="GT8_Glycogenin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050587">
        <property type="entry name" value="GNT1/Glycosyltrans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11183">
        <property type="entry name" value="GLYCOGENIN SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58104">
        <property type="entry name" value="Methyl-accepting chemotaxis protein (MCP) signaling domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="185"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0591973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1069" mass="119879" checksum="C82421B4B4517D6E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBV9</accession>
    <name>A0A8T0JBV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">EngB-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G233500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649:SF13">
        <property type="entry name" value="ENGB-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11649">
        <property type="entry name" value="MSS1/TRME-RELATED GTP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0717">Septation</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035868175" description="EngB-type G domain-containing protein" evidence="10">
        <location>
            <begin position="20"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="EngB-type G" evidence="11">
        <location>
            <begin position="150"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0592201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="37140" checksum="5177C268F581C327" modified="2022-10-12" version="1">MALLHHRLLLLPQCSMALSRTLSHAHATSSAPVLSMVASARLNSRFRVSSLCSRGLGFEEFLQRGFASRRFARVERSRAVLAEVGYTEEADVDLTDQSAQPGDGADKGLKSMPGSNIVLTAGADVGRLAIVKSAEFIKSSSKESECPAAGFPEFALVGRSNVGKSSLINSLVRRKELAQTSKKPGKTQLINHFLINNKWYLVDLPGYGFAKAPTAIRTDWNEFTKDYFLKRETLVCVFLLVDSSIEPQQIDLDCIDWLGRKKIPITVVFTKCDRKKKKKNGGRKPEENIKDFLDRLKPMFADTPPWIMTSSETNQGREELLRHIAQLRILWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JF60</accession>
    <name>A0A8T0JF60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Squalene synthase</fullName>
            <ecNumber evidence="3 5">2.5.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G336500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2 (2E,6E)-farnesyl diphosphate + NADH + H(+) = squalene + 2 diphosphate + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:32299"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2 (2E,6E)-farnesyl diphosphate + NADPH + H(+) = squalene + 2 diphosphate + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:32295"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15440"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the phytoene/squalene synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.21" evidence="3 5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JF60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055056">
        <property type="term" value="F:D-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051996">
        <property type="term" value="F:squalene synthase [NAD(P)H] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045338">
        <property type="term" value="P:farnesyl diphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.600.10:FF:000012">
        <property type="entry name" value="Squalene synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="entry name" value="Farnesyl Diphosphate Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006449">
        <property type="entry name" value="Squal_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044844">
        <property type="entry name" value="Trans_IPPS_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01559">
        <property type="entry name" value="squal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626">
        <property type="entry name" value="FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11626:SF2">
        <property type="entry name" value="SQUALENE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00005">
        <property type="entry name" value="Isoprenoid_Synthase_Type_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01018">
        <property type="entry name" value="Squalene/Phytoene_Synthase_Lik"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="Terpenoid synthases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU368088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0593529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="407" mass="47017" checksum="E6992C50B5CAE24E" modified="2022-10-12" version="1">MGMLGTLMRHPDEIPPLLKLKIAAMQAQRAIPNDPNLAFCYRMLTRVSRSFSIVIQQLRPELRDAICVFYLVLRGLDTIEDDMAIPIEIKVPILKTFHKHIYDPSWKFICGEKNYKELMNKFELVSNAFLNLEEGYQSVIAEMTDRMGNGMAKFIESEVITVDDYDEYCHYVAGLVGLGLSRLFHASGLEEFQPDDLSNSMGLFLQKTNIIRDYLEDINEIPAPRMFWPHEIWGKFGTKLEDFKHEDNSENAVKCLNAMITNALAHAIDCLRYMEAIEDEDNLRFCAIPQIMAIATLAECYNNINVFRGVVKIRRGITAKIMQMRSMDDVHGAFFDFSKKIARKIDDKDPSARATRKHIENIMEHCELHFPEPRVFSIEQETGMDFLLILVVLMLVGLMMYMLYNNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G713</accession>
    <name>A0A8T0G713_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G143300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025886">
        <property type="entry name" value="PP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31960">
        <property type="entry name" value="F-BOX PROTEIN PP2-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31960:SF2">
        <property type="entry name" value="F-BOX PROTEIN PP2-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14299">
        <property type="entry name" value="PP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="1772"/>
            <end position="1955"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="2053"/>
            <end position="2151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1959"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1961"/>
            <end position="1972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1985"/>
            <end position="1997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2255" mass="256640" checksum="4831BDC4DAB14A9C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7L5</accession>
    <name>A0A8T0G7L5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G155200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7L5"/>
    <dbReference type="OrthoDB" id="1865221at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46996">
        <property type="entry name" value="OS05G0488500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46996:SF6">
        <property type="entry name" value="OS05G0488500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="23060" checksum="DE2CB991B7976A10" modified="2022-10-12" version="1">MANTLTLTDPYQYRPNKQRMRKGSSNGSSNSSSNPLTYCDELSSSAAIDIVILILVLGACGFLFTPYFTFIAAEAAEVVPAALVLIGEVVLQAPVAYASATVFTFVAVLASFEIYQYVNRKCDNPNCRGLRKAMELDIQLETEDCVKLSSGRELPWNGGVELGHEQKELEAELRRMAPPNGRAVLIFRNPCGCPAARFEASGSKKARRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7Z9</accession>
    <name>A0A8T0G7Z9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 15">Non-structural maintenance of chromosomes element 1 homolog</fullName>
            <ecNumber evidence="4 15">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_12G148400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Component of the Smc5-Smc6 complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 15">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the NSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4 15"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030915">
        <property type="term" value="C:Smc5-Smc6 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16493">
        <property type="entry name" value="RING-CH-C4HC3_NSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011513">
        <property type="entry name" value="Nse1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014857">
        <property type="entry name" value="Nse1_RING_C4HC3-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973">
        <property type="entry name" value="NON-SMC ELEMENT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20973:SF0">
        <property type="entry name" value="NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07574">
        <property type="entry name" value="SMC_Nse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08746">
        <property type="entry name" value="zf-RING-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12 15" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="13 15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14 15" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="10 15" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11 15" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 15" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Non-structural maintenance of chromosomes element 1 RING C4HC3-type" evidence="17">
        <location>
            <begin position="196"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="250"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="16">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU368018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF08746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0555160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="363" mass="40965" checksum="E70AF283BC616C17" modified="2022-10-12" version="1">MVALDERHHTFLQALMRRGPLSEGESKKMFRELFSSSDDQFFDFLSTVNKELDYVQMEVRGSRDQYSNGGTLYYGVVNKLANEEAKLGTRLTHAQLSFFKAILEAILSDTSASGSILSMQALNLRLDTQNETQTQVEASTSQAAPLKLTLAAKEETLATLVSENWLGRTENGKVILGTKSFLELRSLFKNFEVPFCDVCNEAAIKAQPCQNEDCTVRMHLYCVPRKFSRRQVPRVCPGCRTAWRMLSADDDAANTSDQDPDHEVDDEDDVSRVRAPATTVTRRATRASQGRLKAKLEESTDGENGSSIHKQAKRPCCQRPWCRANNHDIWPGIGELNVLKEQVDQFVRELIVWKVSLREPWSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9L8</accession>
    <name>A0A8T0G9L8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">(6-4)DNA photolyase</fullName>
            <ecNumber evidence="6">4.1.99.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_11G003100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA).</text>
            <dbReference type="EC" id="4.1.99.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.13" evidence="6"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9L8"/>
    <dbReference type="OrthoDB" id="435881at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003904">
        <property type="term" value="F:deoxyribodipyrimidine photo-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003914">
        <property type="term" value="F:DNA (6-4) photolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032922">
        <property type="term" value="P:circadian regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043153">
        <property type="term" value="P:entrainment of circadian clock by photoperiod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.579.10:FF:000004">
        <property type="entry name" value="Cryptochrome-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.579.10">
        <property type="entry name" value="DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="CRYPTOCHROME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455:SF9">
        <property type="entry name" value="CRYPTOCHROME CIRCADIAN CLOCK 5 ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="Cryptochrome/photolyase FAD-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="Cryptochrome/photolyase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="11">
        <location>
            <begin position="48"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="564"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="580"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="591"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="296"/>
            <end position="300"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="337"/>
            <end position="344"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="435"/>
            <end position="437"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="9">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="9">
        <location>
            <position position="422"/>
        </location>
    </feature>
    <feature type="site" description="Electron transfer via tryptophanyl radical" evidence="9">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00066798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00067640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602081-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0555791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="614" mass="69981" checksum="73EB0130EFE9981F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAV3</accession>
    <name>A0A8T0GAV3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G034300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050715">
        <property type="entry name" value="LRR-SigEffector_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752:SF195">
        <property type="entry name" value="LEUCINE-RICH REPEAT (LRR) FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035789156" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="domain" description="DUF676" evidence="5">
        <location>
            <begin position="123"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="4">
        <location>
            <begin position="328"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="847"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="997"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="1188"/>
            <end position="1282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1494" mass="166841" checksum="1B55FA0F20418E1E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBJ6</accession>
    <name>A0A8T0GBJ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G000200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GCN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019887">
        <property type="term" value="F:protein kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034198">
        <property type="term" value="P:cellular response to amino acid starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000090">
        <property type="entry name" value="eIF-2-alpha kinase activator GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000096">
        <property type="entry name" value="eIF-2-alpha kinase activator gcn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000162">
        <property type="entry name" value="GCN1, eIF2 alpha kinase activator homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056810">
        <property type="entry name" value="GNC1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057546">
        <property type="entry name" value="HEAT_GCN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346:SF7">
        <property type="entry name" value="STALLED RIBOSOME SENSOR GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23346">
        <property type="entry name" value="TRANSLATIONAL ACTIVATOR GCN1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24993">
        <property type="entry name" value="GNC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23271">
        <property type="entry name" value="HEAT_GCN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25786">
        <property type="entry name" value="HEAT_GCN1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="1327"/>
            <end position="1560"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1501"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1621"/>
            <end position="1659"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="1646"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="1739"/>
            <end position="1774"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="1995"/>
            <end position="2216"/>
        </location>
    </feature>
    <feature type="domain" description="TOG" evidence="6">
        <location>
            <begin position="2223"/>
            <end position="2458"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="2393"/>
            <end position="2431"/>
        </location>
    </feature>
    <feature type="repeat" description="HEAT" evidence="4">
        <location>
            <begin position="2518"/>
            <end position="2555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="817"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0555734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2627" mass="283816" checksum="55CE9962A2AFC269" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBT8</accession>
    <name>A0A8T0GBT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G171500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBT8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14394" checksum="003805EFC8E56861" modified="2022-10-12" version="1">MSWSQRPVKNNAMNILSLILVSKWMDSPSLSIAQYCKRVQKSQQLFELLDYTGIVRSQCAWNLARLRLGMNLGSCELGDERSPRTARMIGPLQQWAVTSPQFCMLPFVVLSSSLHPFSTAVSADCSVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBX6</accession>
    <name>A0A8T0GBX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G087900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035803050" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6980" checksum="B66CC55E19F368F0" modified="2022-10-12" version="1">MNERPRFTGFLLVVLLLELQQGEGYVDERMLEERNELPLHMHSTYAGSNGSRPSSIFNWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE56</accession>
    <name>A0A8T0GE56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G172900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="302"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="190"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="450" mass="49113" checksum="B09C1D8D8DE460A6" modified="2022-10-12" version="1">MFANWSSISNSRHSPDSPLSTSALTSLPHHYTTPSTTTRRRCPHALHRISKPCAAPWKHATSSSLPSPHTHARSLFAARPKPRTRCRTRSHNQRHSSTDDAHHPTALPSRSLLRRAGAATTPSAGAQIHRPSGPSPPTPLPRPRPRPRVLGHWGRRSLRRSLAPPQSPQEPALVSSRLVSSQPAPAPAFRTKRSPRAKPRLNITPSEARRYAIWARGESPAADSAQPARGRAVLSNDRHAPALPLDMQARDSGIVTAAAHGFMAASWLHSCFMYRLHGASHGLMLRHTMLACSHARTHCIPALRRPGSGPQRRSRRNPPPAPRRSIAHPLPAARRSLRQSRIHSLMLRLPPWPRRADRHRRRPRLPVCLFAPLCTLPVHSLPACLATTASALSTSAPRCLPSALGAGFRCARPPLPLQCSAVQCSAPAIPRYLPGGSISRCRALSAESSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEU8</accession>
    <name>A0A8T0GEU8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G098800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035788400" evidence="1">
        <location>
            <begin position="16"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6966" checksum="E8FC26EDE600CE4D" modified="2022-10-12" version="1">MTLMWSLVTSKPALCISVLGMQPQCFRGRSTKFLYNRFECFRLNFCSSHSWNILCRVLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF04</accession>
    <name>A0A8T0GF04_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G075300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035822546" evidence="1">
        <location>
            <begin position="23"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="19272" checksum="D9AC48545256EA98" modified="2022-10-12" version="1">MAASRTSLFLLGLVVLATVCAAVEATAPAECKCGSGGAVDLVDVKLKLDVNLKKCEPALRVLVDGVVKVADRAKALRVCAGRKVTSLAPLAVHLKVNGVVNVNVEVLGKDGKPALKAVVKLDLAKLAVKVVDGVHHLVLDVVHDAKKAQLVFSCLGKQVHAIDIRAHLDVLGLVNVGVGVGVGIGRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF67</accession>
    <name>A0A8T0GF67_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G079100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF67"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="57782" checksum="0539D4D22D3E7479" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH30</accession>
    <name>A0A8T0GH30_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G101900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH30"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37663" checksum="0920DC003031AFFA" modified="2022-10-12" version="1">MGNCNHKFHITCIVKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYEWGKSLAWNPETMTHQLSTANDAGMDDLSWMTHDYEVEMRAREIPDAKDREFFCRNFGGHWSIHGNRFFRFPKPEVVVDADGKRREVERDYGQLDEYKMYDRTPVGRALVLAKLEEAIQHRRTFTEESFKYSDLDYWVIIKKSDDALQKIVNDWRRALRAEDNSSRWSRNRIEKIVQETVAKIEKAKELWNGKNSKKRNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHG2</accession>
    <name>A0A8T0GHG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">enoyl-[acyl-carrier-protein] reductase (NADH)</fullName>
            <ecNumber evidence="5">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_10G030000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the NAD-dependent reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Catalyzes the last reduction step in the de novo synthesis cycle of fatty acids. Involved in the elongation cycle of fatty acids which are used in lipid metabolism. Required for normal plant growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="5"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.400:FF:000001">
        <property type="entry name" value="Enoyl-[acyl-carrier-protein] reductase [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000192">
        <property type="entry name" value="Enoyl-[acyl-carrier-protein] reductase [NADH]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.400">
        <property type="entry name" value="Enoyl acyl carrier protein reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004957">
        <property type="entry name" value="PRK06300.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00053870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0558460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="392" mass="40682" checksum="4921F5AD71ED913F" modified="2022-10-12" version="1">MATMCSRAVAVAATISSPAASTNAHRRGARAMVSSFQGVRTLGAGAAIAPLRCVEQAMRKKVLVGGVRAMASANGASAPSGLPIDLRGKRAFIAGVADDQGFGWAIAKALAAAGAEILVGTWVPALNIFETSLRRGKFDESRKLPNGGLLEIAKVYPLDAVFDTPEEVPEDIKNNKRYAGSSAWTVQECAEAVKADYGTIDILVHSLANGPEVTKPLMETTRKGYLAAISASTYSYVSLLKYFAPVMNPGGSSLSLTYLASEKIIPGYGGGMSSAKAALESDTRVLAFEVGRKYGIRVNTISAGPLRSRAAKAIGFIDDMINYSTANAPLQKELEADDVGHTAAFLSSPLASAVTGTLIYVDNGLHAMGLAVDSPSVAKAAAPAPEKTNVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHG6</accession>
    <name>A0A8T0GHG6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G170900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004128">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000001">
        <property type="entry name" value="Cytochrome b5 reductase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051872">
        <property type="entry name" value="Cytochrome_b5/Flavoprotein_Rdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237:SF1">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46237">
        <property type="entry name" value="CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="6">
        <location>
            <begin position="106"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="22"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0557987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="20276" checksum="5D97B0340C9A6C6E" modified="2022-10-12" version="1">MTLNLQPPSSSPPSSSPHRDSSSSSSSSEAASALTSLSLSEPPNDLHQDGTASAIAIAIAVPQVMPPPKPTPRAKVPLEKGYSQMVWLRLLQTEPDLAGLKGQSPKRLITMQEVKQHKTEEDAWTVLRGRVYNISPYIRFHPGGKDMLMKGAGRDCTALFNKYHAWVNAEFLMEKCMVGILDVPPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHX4</accession>
    <name>A0A8T0GHX4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G155100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHX4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="17386" checksum="446C172CEBADD68D" modified="2022-10-12" version="1">MDLHSSKFSSTVTGSLSMSRVCLVGGLLCENVSFVVGYNLLGLASPSKQSSNKMFTKNQALNHQQAGTNQTCEASWHQKLRMCIHLILQRCLAKLYKTSSPRNSTSNAPPLKSPPPNSYSTRTTPETWSSNHRKDELMAPSPTVLGLLQKEISFSQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIF7</accession>
    <name>A0A8T0GIF7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G088400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="138"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="47661" checksum="A79A415C9B532B89" modified="2022-10-12" version="1">MASSSHETRVCSDDQTIQEPWSLFSFLIGLFRSPSSSASWYHSARIQRMIEKSGEFRTEVESESEAAVQYEIESSKVHWSEVNPALSETPHMGYSNRGWFKLLKRRQYYVYGKDQIVFKQYDEEQVWNLFRDSLGHDLVVGKKLAEGGQAEIYEANIGDGDSCVVKVFKAGCILHEILEKQIPPALLHSSYVRELGWISHATLLKDERFLDRFAFVMGKAWGDLRKLIDEQMIQSGNQCPPFPPNQVWGLMREIARGMSALHCQNPPILHNDLKAANVLVQLNHDTGKPAMDKRGMYLVYVADFECSVGVLGTAFWRAPEILQQYREKVSKVVFTKKCDVYSFGMTCYELISGCLPFEDHPSNDYDMVLNGSRPELPSDLNPLFKDIITSCWSADPLERPTFDDIIDKLYENANSYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK90</accession>
    <name>A0A8T0GK90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyclin-dependent kinase inhibitor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G103600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK90"/>
    <dbReference type="OrthoDB" id="6373236at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008541">
        <property type="term" value="C:proteasome regulatory particle, lid subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004861">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051726">
        <property type="term" value="P:regulation of cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.365.10">
        <property type="entry name" value="p27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003175">
        <property type="entry name" value="CDI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044898">
        <property type="entry name" value="CDI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054559">
        <property type="entry name" value="PSMD12-CSN4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040134">
        <property type="entry name" value="PSMD12/CSN4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855:SF1">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10855">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02234">
        <property type="entry name" value="CDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22241">
        <property type="entry name" value="PSMD12-CSN4_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0649">Protein kinase inhibitor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSMD12/CSN4-like N-terminal" evidence="5">
        <location>
            <begin position="45"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-dependent kinase inhibitor" evidence="4">
        <location>
            <begin position="242"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="178"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="281"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="319" mass="36395" checksum="F7AF3054FFCBA8D0" modified="2022-10-12" version="1">MTMAIRSKKDMEAVAVKEGVEDEKLEKLIREQRVVALQEKRLDAALEELLKLEKEARSTGDAPRIQRVAVAIVQLCYDARAWKTLIKQILFLSQRPDQLNQAIVAMVQQAVSYLNDIPDLDTRNELAEALNNVSSSKGLQSLCWYLLLTPHESLSGQSKTQMADLDLSGIDLSCESQEERAERQFQESTQQQVLSPDFESRPTTPPQQRMRVKDMSPSVCRAPLKKKPYIIRKPMGPVRRRLFSQATPSDVEEFLSELEQSNHQRFIDRYNFDPVKEKPLPGRFEWSPQRLPRPELTRATSVDSSTEVRKSELASTLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GL72</accession>
    <name>A0A8T0GL72_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G095900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GL72"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13008" checksum="F7784839FAEFB94F" modified="2022-10-12" version="1">MPLKLCGPRGSHSPATLCTYLAGKFRRRLHSLLWRWVLGRFQVEFSGLGFGVGWAPRGAIQKLGYAGVCTQRTVFFSKRRKNSSLCAEHPAVYPSLADAPVLLLQSGAVSRHRVWVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQN3</accession>
    <name>A0A8T0GQN3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G048400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="13064" checksum="EB693D053103C75A" modified="2022-10-12" version="1">MNPHSNQSPDGSSTPANLITPRPTSPSTRKPLSNLSNNSATRFTNCNKRYTQPSFPSLIQIQPTLPPSDKHPPVTALPDSPKIILTLTLNASNDTSITPARTTSNTQAMTRAIAKLQHISH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR49</accession>
    <name>A0A8T0GR49_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G005000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035267">
        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012423">
        <property type="entry name" value="Eaf7/MRGBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581">
        <property type="entry name" value="MRG-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13581:SF5">
        <property type="entry name" value="MRG_MORF4L-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07904">
        <property type="entry name" value="Eaf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="23"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0560684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16471" checksum="1E887C44595C7141" modified="2022-10-12" version="1">MGDNVQHRPPPADGTTSLSSHRSTPAYTPPSSASSPFKKGMQQVELELRLLEAFAIYRPSMLVGMHRHFILFGLMDHLERRSVTRWCRLNQRFSPDEVLQLLDRFFNMDLLKPGDEELDLVNHEEDFSLPPSMFEEIKKKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSV4</accession>
    <name>A0A8T0GSV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G110500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="19919" checksum="0A8ACB1D0C31E331" modified="2022-10-12" version="1">MDRVHKGYLQHNDISPGNVLLHFPEDKVSEVYIGVCDWGLASRVCETTPSRYGYPSDEARTAAFKERGSFVAPELWYTYGKPNSETSYETLRRRHLYTQAANAYSVGVVANKIWDNEDDIDLFKDTAGKARFAVALKELTNPDPKSRSTLRLVHATLTAPPYNFQIPECCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT86</accession>
    <name>A0A8T0GT86_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G091200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT86"/>
    <dbReference type="OrthoDB" id="294702at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763:SF51">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45763">
        <property type="entry name" value="HYDROLASE, ALPHA/BETA FOLD FAMILY PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="68"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="38511" checksum="FF2A1F971CC30B33" modified="2022-10-12" version="1">MGSPGVWCNVLVVLIIGVVGILVKVVTPPPGSTTLDGSQLTAPRVQMRDGRFLAYKQVGVPLETAKHVIVHVHGYGGSRHLTYPISQEVTEEDGVCMISFDRAGYGQSDANPNRSIKSEADDVVDLADGLGLGRRFYVTTVSIGGYTGWGLLKYHPDRLAGMAMQAPATNFWWSGLPASAVKAGWAQLALGDKMAFCVWHYFPVLTYWHMTQTWLPTSSVAPHAGLQNFSPGDQELMKLSGSRLAKTTPEHSKEAAQRGPIESTFRDLTVMFSSWDFSPLEIRQPSGSVSVHIWQGTEDYLVPVQLQRAVANAHPWVQYHELPNHGHFLNGVPGIPDRVVRTLLGTRTTTAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU45</accession>
    <name>A0A8T0GU45_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G083000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19093">
        <property type="entry name" value="AKR_AtPLR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF5">
        <property type="entry name" value="PYRIDOXAL REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="376" mass="40795" checksum="7838AFE844859896" modified="2022-10-12" version="1">MAMAMGMAVVVVQPTALCGPSVRAELSSSLSKLSPLPLLRSLGIGKSWDNVKVGPLTVSPMGLGTWAWGNQLLWGYEEEMDAELQEVFNLAVSKGINLFDTADSYGTGKLNGRSELLLGKFIREYPGKEQVAKNVNIATKFAAYPWRLTPSQIVSACKGSLKRLEMEQLALGQLHWSAANYAPFQEQALWDGLVAVYEQGLVKAVGVSNYGPKQLRRIHKYLDRKGVPLSSVQVQFSLLSKGTDQMEVKAVCDELGIQLIAYSPLGLGMLTGKYSPTNVPSGPRGLIFKQVLPGLGPLQDTLKQIAKRRGKTVSQVAINWCICKGAIPIPGVKSLKQAEENLGAIGWRLNREEVASLESAADQAPRGMIQNIFQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVQ5</accession>
    <name>A0A8T0GVQ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G162300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07042">
        <property type="entry name" value="STAS_SulP_like_sulfate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.750.24:FF:000002">
        <property type="entry name" value="Sulfate transporter 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="entry name" value="STAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00815">
        <property type="entry name" value="sulP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="SULFATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SpoIIaa-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="400"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="7">
        <location>
            <begin position="518"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0562647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="654" mass="70728" checksum="C136BA40B5C80711" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW35</accession>
    <name>A0A8T0GW35_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G040200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11513" checksum="FD69891414FEEB9F" modified="2022-10-12" version="1">MRRIGVIVLLVIYFLSCVVVYGMQLKVSYSTLDSASVQNTAVRGRYRLTLRSYYIRYHLEQIRGQQAQGPERPRHHFQATGQIVDAAILGSLNSAVICENAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWP2</accession>
    <name>A0A8T0GWP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SPX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G057100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14479">
        <property type="entry name" value="SPX-MFS_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051068">
        <property type="entry name" value="MFS_Domain-Containing_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045264">
        <property type="entry name" value="SPXM_SPX_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23510:SF64">
        <property type="entry name" value="INNER MEMBRANE TRANSPORT PROTEIN YAJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="396"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="561"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="597"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="625"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="8">
        <location>
            <begin position="2"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="518"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="518"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="528"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="749" mass="83493" checksum="EC1EE946A8D68B62" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYE7</accession>
    <name>A0A8T0GYE7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G103500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12560" checksum="D22E5286F3C139E9" modified="2022-10-12" version="1">MAGRVVRRHDNYFVTRDSSISSPTTVPFRLLRQFHFRSTPRQFQDQNHDSSNIVPGNRVPCVPTLLIADHCVRYSTCVAVEEGAGVIYRGSVVWCATVVGYVVVIHASAGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYQ8</accession>
    <name>A0A8T0GYQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PSII 6.1 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_8G017100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the psbW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009806">
        <property type="entry name" value="PSII_PsbW_class2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07123">
        <property type="entry name" value="PsbW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0563264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="24287" checksum="6E7751D7670F2D7B" modified="2022-10-12" version="1">MLMRTDEHMEPSKRTPRQTQESAPIGRGPAADDALSRGGWHPHSHHPHLAATPAPLPPCKLPPSPSSTLQSILRQALDLTPNKGRRHPPPSPAMAAVASTSAVASPCFLQRPLATPAALRASARPVSGLPALRMPKIVCSAEKKESAKTEEVNGLPQLAAAVTSAATMAYAHPVFALVDERLSGEGTGLGLGVSNPKLTWILVGVTALVWALFFTYSSKLPEGDDDSGLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYW0</accession>
    <name>A0A8T0GYW0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="4 8">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G118400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="4 8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00948">
        <property type="entry name" value="FBP_aldolase_I_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000140">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029768">
        <property type="entry name" value="Aldolase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00158">
        <property type="entry name" value="ALDOLASE_CLASS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0562102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="40439" checksum="8E9C4ECF48E475B5" modified="2022-10-12" version="1">MSAYWGKYAASNPQSKGAHQKHACWKCDELIRTAKYIGTPGKGILAADESTSTIGARLTGINVENTEANRQALREMLFTAPGTHQFFSGVLMFEETLYQKTLAGKPFVKLLEEGGVMTGIKVDTGVVQLAGTNGETTTQGHDGLGARCKKYYDAGARFAKWRAVLKIGHTEPSELGIQQNAQGLARYAILCQENGLVPIVEPEVISDGSHDIRKCAEVTERVLAACYKALNDQHVLLEGTLLKPNMVTPGADAPKVSCEIIAKFTVRALQRTVPPAVPAVTFLSGGQSEEEATVNLNAMNSLQTLKPWTLTFSYGRALQASVLKTWGGEKKNWVAAQRVLYNRAKANSEAVFGKYKGDSGGDSGNLFVKDYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZW3</accession>
    <name>A0A8T0GZW3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G073600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12692" checksum="F1C165FCE087A357" modified="2022-10-12" version="1">MYLHAKTSNHLRQTQTRLRTPPTKDHLFLSNQPKDMKHNLSATTTTTPPAINRHKHRNNNSTSSQTRSTLTEIAREDEHMNISSKLQASGYQFGHLHIMPTCLDRTTSGAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H069</accession>
    <name>A0A8T0H069_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Solute carrier family 35 member F1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G057000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC35F solute transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H069"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009262">
        <property type="entry name" value="SLC35_F1/F2/F6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052221">
        <property type="entry name" value="SLC35F_Transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233">
        <property type="entry name" value="DUF914-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14233:SF4">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06027">
        <property type="entry name" value="SLC35F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="363" mass="39566" checksum="583C588D8CC4181B" modified="2022-10-12" version="1">MENWKGWIVEKAKGNGTGLKAIAVGQTLSLLVTCTGLTSSVLARNGIDAPTTQSLLNYVLLGLVYGSVMLYRGKEIQISWYWYLLLAFFDVEANYLAVKAYQYTSITSVMLLDCWTIPCVLLLTWLVLKTRYGSHHFVGVAICVGGLIMVIFSDVHAQDRSSSGSNVLLGDALVLGASMLYAVSNVSEEFVVKKVDQVEFLAHVGFFGAIISLCQLVALELDELQAIHWSVSSIAPFIGFALSCFGFSSMVPWLLQMNGATMLNLSLLTSDMWAVAVRALGFHESVDSLYFVAFALVAVGLIVYAFAGEPSPSPEGILAAPGEKYKQIDQVEKPVDQLTPEEELSCLDIHVDMQPEKLTSIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H094</accession>
    <name>A0A8T0H094_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G156600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H094"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6621" checksum="0B29F0C99FD9C739" modified="2022-10-12" version="1">MKIQAPSTRCHAMYLNLILEMHLCIVVPCSVIAYQVPLNFNGHVPQQLYVETGNCVCIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0M5</accession>
    <name>A0A8T0H0M5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G104000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0M5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="238"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="740" mass="83679" checksum="A5BA558E87AF2E28" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2G8</accession>
    <name>A0A8T0H2G8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G197700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13923" checksum="7DC22644E7EC3360" modified="2022-10-12" version="1">MEILVSEVLLFVSSLEGCIVMLAPLSNMTVYLGFDNDFSSCPYRDRTGFRIVCSESRFLSVLFCDMKYLFDLYVTIFSVHFSFCFLLIWHHNVAPTMNVRSMSPLDHMIKLCDCLENIMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4W1</accession>
    <name>A0A8T0H4W1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G100400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 12">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4W1"/>
    <dbReference type="OrthoDB" id="282152at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006386">
        <property type="term" value="P:termination of RNA polymerase III transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10509">
        <property type="entry name" value="Zn-ribbon_RPC11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034014">
        <property type="entry name" value="Zn_ribbon_RPC11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239:SF12">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02150">
        <property type="entry name" value="Zn_ribbon_RPB9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="Zn_ribbon_TFIIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57783">
        <property type="entry name" value="Zinc beta-ribbon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 12" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="13">
        <location>
            <begin position="66"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="4"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR005586-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0566966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12737" checksum="2E9C60F8AA80A14E" modified="2022-10-12" version="1">MDFCPTCANLLLVENPSMGRPLRYFCPTCPYVYIIDRKVSKKLKLKKKEVDDVLGGEDAWKNVDRTSVTCPNCAYGQAYFMQIQIRSADEPMTTFYKCCNIDCNSRWKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5E3</accession>
    <name>A0A8T0H5E3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G066100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5E3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043489">
        <property type="term" value="P:RNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838">
        <property type="entry name" value="NUCLEOLAR PROTEIN OF 40 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15838:SF1">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="196"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="424"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="54009" checksum="4DDE49A9598B07E1" modified="2022-10-12" version="1">MTTQRTSMVYQTKDWSIKSNEEDKFNARNGQIENHYNTKKRSYEMIKESTTRSRNENVSKIKEHCDISKHIHSIQRIKNDRNQYLDSRMNVNFDNYEKSNMNGVTSREEDNNSSQIFDRGYYGSIHDHRNRNRFGTQYGCYKFGITNPEAGLCQDNNEEKELIDSRNVKTFDSDERHNSLPRLASKKVLTSTSTLYSIQKAVVHSIRPFGIFVQMEGYQDHGLVHISEVSNHEICTREDSEEAKMKALSTIANEGKVVWIKVISVRSENGKTRIGCSMKHVDQEDGSDLDPNNIQLEQQSSQPAPSQVEHYKMKPESATVMEEDDAVAMVQSHRKGKAMMMPRELSSGQMLPPCGIPKHLLATGSVGRGRAMVQPAWMKHGIGIGGPVAAASLMVEEEKQRSDVTERSMPAMVEDGTAVIARLKEEKRRRKVERRRRKERRQGRSCRGERHKRRRNGEERHGHRKKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA91</accession>
    <name>A0A8T0HA91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G001100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037490">
        <property type="entry name" value="WAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33883">
        <property type="entry name" value="WPP DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33883:SF10">
        <property type="entry name" value="WPP DOMAIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="772"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="965"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="385"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="663"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="719"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="893"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="965"/>
            <end position="977"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1133" mass="130553" checksum="C927AF8AD6C303AC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAG5</accession>
    <name>A0A8T0HAG5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G017700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.340:FF:000029">
        <property type="entry name" value="Coiled-coil domain-containing protein 90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024461">
        <property type="entry name" value="CCDC90-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14360:SF1">
        <property type="entry name" value="PROTEIN FMP32, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07798">
        <property type="entry name" value="CCDC90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="262"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0568413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="285" mass="31325" checksum="00ADAAB24537CA67" modified="2022-10-12" version="1">MAAAAARRAVAGNAAVSLQQQLAVVVRGGGVAAELVGADVRVKGLGLGLGSGLVPRAHDWQFLQDRRPCVLYSDGLSPLKAWNYAAVRGYYMRNISQLVAPANNKRAFLVDTLALVRRLEAQGLTPKQAEAITAVITEVLNDSLENVAQSFTSKTEMTRSEMMAEAALSKFKGEVQSSQEHHFATLQRETERLRTDIDKMRSELRYEIDKVTAGQRLDLNLERGRIREELATQSSETSNLTNKLDREIHTLKTQLEAAKYDVIKYCIGTIVSVTAVGLGLLRILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBM2</accession>
    <name>A0A8T0HBM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G070800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034474">
        <property type="term" value="P:U2 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038902">
        <property type="entry name" value="INTS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053966">
        <property type="entry name" value="INTS1_INTS2-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053965">
        <property type="entry name" value="INTS1_R4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022145">
        <property type="entry name" value="INTS1_RPB2-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21224">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21224:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22929">
        <property type="entry name" value="INTS1_INTS2-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22928">
        <property type="entry name" value="INTS1_R4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12432">
        <property type="entry name" value="INTS1_RP2B-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrator complex subunit 1 RPB2-binding" evidence="2">
        <location>
            <begin position="393"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 1 INTS2-binding" evidence="4">
        <location>
            <begin position="1155"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="domain" description="Integrator complex subunit 1 R4" evidence="3">
        <location>
            <begin position="2318"/>
            <end position="2409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF22929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2447" mass="272198" checksum="517766A46DDBA3BF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEA7</accession>
    <name>A0A8T0HEA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G080000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9764" checksum="98A69112E0DC203D" modified="2022-10-12" version="1">MITIFRIKHTSLIMLERGSGSGFIPLLKIDTWLCVYLSVFGETRVLGDIIHNCQVPLGGVSATSDRLSDVCVFKTSSSGSDLTINIITGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGC0</accession>
    <name>A0A8T0HGC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein phosphatase 1 regulatory subunit 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G179500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1130"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1133"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1153"/>
            <end position="1162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0570673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1306" mass="147285" checksum="E59BD6D1B5B806F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI56</accession>
    <name>A0A8T0HI56_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rad60/SUMO-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G062900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47813">
        <property type="entry name" value="UBIQUITIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47813:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad60/SUMO-like" evidence="2">
        <location>
            <begin position="186"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="259" mass="29061" checksum="565BE03AB5E0F244" modified="2022-10-12" version="1">MAARAEDVIALKRLSIDPMEDDDDDEFEPLYNYSRTVVPVPTFLSDDSDDEDLVTASAPKRRPEIAPAKEPSTRAPQKAPVKKIVLDDDDDDDSWLMSSSPQLPKIPQPAFSTGNLALRQLRERRKELMMLQQLASPGAIKNIEELARIQAQQRPEVEPLPKVLESDVEPPKSEVGASEEKEKVLIKVQDKSGNSQSIRIYATDKFEKLFAQYAKMVKASLPNLSFRFDGDQLASNSTPKEHDMEDEDIIEVYDKSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLM5</accession>
    <name>A0A8T0HLM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">V-type proton ATPase subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG036900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3240:FF:000003">
        <property type="entry name" value="V-type proton ATPase subunit D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="V-TYPE ATP SYNTHASE SUBUNIT D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="249" mass="28036" checksum="B3926E6A5C21BD17" modified="2022-10-12" version="1">MSGSTQRLNVAPTITMMGVVKARLVGATKGHQLLKKKSDALTMQFRQILKRIVETKESMGDTMKASAFSLTEAKYAAGDNIKYVIFENVDKATVKVRARHENVAGVKLPRFENFTDTGGSKNDFTGLGRGGQQIQLSRSAFLKSIEILVELASLQTSFLTLDEAIKTTNRRVNALENVVKPKLENTISYIRGELDELEREEFFRLKKVQAYKKKEVDKQLAMNKAYMEQGLKRPISDEANTHKDEDLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HND7</accession>
    <name>A0A8T0HND7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG083800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HND7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035771466" evidence="1">
        <location>
            <begin position="24"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10997" checksum="B83D8AE4DDFB93A4" modified="2022-10-12" version="1">MIHSHMWFTVEILASSTVPSCSSFGLGKQGSSEEQLLLLRKEMASWQCAIRDGVLSQLLRQVTTPPDSWDSAYMSLPGPLPRQQGTIQDVENARHVCSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNI7</accession>
    <name>A0A8T0HNI7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG098600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="13416" checksum="4495202E9FFE1A55" modified="2022-10-12" version="1">MHWSPDLGGPRRAHISLYPVDSIQPLPTSRQHLSSIRAASTSNKVLDIPNQRQNQSRFADDTLRCYPEESNKQRQVQQDYSKLYLAKMANAHAKGCSPTIHVPTTTTGKPIGLRSAWHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRP7</accession>
    <name>A0A8T0HRP7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat shock factor binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG175700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSBP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070370">
        <property type="term" value="P:cellular heat acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.430:FF:000003">
        <property type="entry name" value="Heat shock factor binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009643">
        <property type="entry name" value="HS1-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19424:SF0">
        <property type="entry name" value="HEAT SHOCK FACTOR BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06825">
        <property type="entry name" value="HSBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="10485" checksum="73D8C17BC7CAD262" modified="2022-10-12" version="1">MDSGGHGGANISQHEGVDATTQKTADLTAFVQNLLQQMQTRFQTMSESIITKIDEMGSRIDDLERSIGELVKETGHVDVMPASPSNSSLRGGSGMESM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRV9</accession>
    <name>A0A8T0HRV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG202200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_bS21"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0573702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18642" checksum="1B01F94298CD459C" modified="2022-10-12" version="1">MNQSGSSSEYGIKSILCLATHSLGVSQGLWGQRAGLVSQYGSMLGAGNQQVRNVMVEVTNDNLERAIRKMKRRLKDDNGIKLLRERQYFRKPSELKVLARKERDKRIAEKAFRAKLKWITARQAKLIREALLHHTSSYLSRSLYISTIAECLRTLSLPAPTQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRZ0</accession>
    <name>A0A8T0HRZ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG207400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12981" checksum="322DC5CF6357C65D" modified="2022-10-12" version="1">MELGAAVPREEMDALKSKCGNTSTQGITSQERAEKQLQHQAAYNSSSQQTLCRPCARRKQHHQTNRDRQVNMKQRRNGHHNRGFEVHLNRRPPHMQANALRSHPNRPPTRLGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTP6</accession>
    <name>A0A8T0HTP6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG234500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DESIGUAL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009606">
        <property type="entry name" value="DEAL/Modifying_wall_lignin1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052222">
        <property type="entry name" value="DESIGUAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31769">
        <property type="entry name" value="OS07G0462200 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06749">
        <property type="entry name" value="DUF1218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0574105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="22379" checksum="5F237C37240699B8" modified="2022-10-12" version="1">MARVSKPLVGIAFFCDILAFGLACGAVARRSRAAPYYAEPGYLTCGYTSDASTGLAATAFVFLLFGQVLITAATSCVCCGKTHYTPGFGRICSILLLLISWVSFAIAEIHLLTGSVVNNIKTQGQVDIGVTTQDEVNCAQAKKFIFAVGAAFTFLTTAFSLVYYFMQAGAESKDQQWNSYRGEADGYYRQSDPYTAHDGPHVGMTAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU63</accession>
    <name>A0A8T0HU63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG250000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="8767" checksum="6E776DFA01EE6445" modified="2022-10-12" version="1">MLIWLNKLSWNFSKDVTVGLGSMLLSMAFSNTLSSLVGSTSSQSSIVGSVIIEESSLFEPHCDRPPPLLLAQATVRVQTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV47</accession>
    <name>A0A8T0HV47_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG274600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="9229" checksum="282F5E8CED754866" modified="2022-10-12" version="1">MLKWIMYCDVSLHVAAGNDRKMFQSACKYTFQCIIDLLSIDISVKEALIDLLIPNLFVPQENCRHSVLSHWRIDYVRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVJ9</accession>
    <name>A0A8T0HVJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Dynein axonemal heavy chain 2/5/8 coiled-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG317400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056759">
        <property type="entry name" value="DYH2-5-8_CC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703">
        <property type="entry name" value="DYNEIN HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45703:SF32">
        <property type="entry name" value="DYNEINS HEAVY CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25007">
        <property type="entry name" value="DYH2-5-8_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein axonemal heavy chain 2/5/8 coiled-coil" evidence="2">
        <location>
            <begin position="4"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12966" checksum="42A36689A1F7344D" modified="2022-10-12" version="1">MPKKRNEEDCNKPPQNLGELTQTAQLWRTICDECTQTETRFGPLHEKYRILNKFEVPLHEEEVFLLERLPNAWEEFKIMLAEVELKLENAKNNFRDTLEEMVGDFVVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVP3</accession>
    <name>A0A8T0HVP3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG291400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="43" mass="5076" checksum="27608F63611990FE" modified="2022-10-12" version="1">MRWSWAALEYIIRRALHFSSHDSAWCSPRDIKCTSPQRGIDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW79</accession>
    <name>A0A8T0HW79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG306700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11843" checksum="4B573D1737733DE0" modified="2022-10-12" version="1">MSSSVPMTHLSTVILMEWIQENYGGVENEDDDELIVFWILSQTCSWARQYSRNFPRMIGNAHMNYLFSLEDCRLYYNPAMYDYENDEVNFAAFWSRVQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXE0</accession>
    <name>A0A8T0HXE0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EamA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG337900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXE0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="20451" checksum="83DA599D7EE33988" modified="2022-10-12" version="1">MVSARWIDRAGPHAALIFGAAGFGGYFVLTKASLSGGVDPFVFGTYRDGIGFLTLFLYASCFERQHWPKVLLEVAGLVFAMAVVGQWFFVKWKEQKTHCLINCTARSASAHPTERIQDLLQEDVEVKRRREKVKRQASVLSRLTRQLSMNEARASAATGESRESGKTPDFTQGSLHFGIFVSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ92</accession>
    <name>A0A8T0HZ92_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G044600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ92"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="255" mass="27514" checksum="69EB123465DD7E52" modified="2022-10-12" version="1">MVSICISISFLPVGGGRILGGRRGCDLLGRGGGVRREWVLDLGRMDRRIMVVVMVMVMVMAAVEVMVPVAALAATPPSIQPITCRLPSTSMISTIFCNSSDEQGMETQTKSCQGFLTMAEDSPSADCCRGLNRVAYNRTACICKLTFYPPASHNTSRQLDLPRLCGVPTNLCAQCPAFLTSISNSNGTNTHLQSPAKFSAPGCGCARHRSHPYHEKFASILVTNSCINSFHKLFASILLTNSSNYLPLTNFTSDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZM1</accession>
    <name>A0A8T0HZM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G054400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1017" mass="112483" checksum="104535CF41E8A5C9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1I9</accession>
    <name>A0A8T0I1I9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G081700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1I9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="11442" checksum="EFCE83FC83A1337C" modified="2022-10-12" version="1">MNCTKASVRWPTLQPCEETFDGREAEAATVVCVCSSTWSAMRVLYLPYWATLMKRRLSLYQTLMMLSFALTLGKTKEEEDRVMDMDMRMYDFQQTMTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1W4</accession>
    <name>A0A8T0I1W4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G107900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1W4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035797249" evidence="1">
        <location>
            <begin position="17"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6446" checksum="8F789D885AB6EDB5" modified="2022-10-12" version="1">MYILILKLKLLAHILANSITETEIAGLSCVQLGLVWECFCLYQCLLWRFYTCRMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I246</accession>
    <name>A0A8T0I246_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G124000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I246"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="49"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="326"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="639" mass="73797" checksum="BE78A5B0BF763476" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2S1</accession>
    <name>A0A8T0I2S1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LIM zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G177700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09396">
        <property type="entry name" value="LIM_DA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.110.10:FF:000167">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.110.10">
        <property type="entry name" value="Cysteine Rich Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045218">
        <property type="entry name" value="DA1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022087">
        <property type="entry name" value="DA1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001781">
        <property type="entry name" value="Znf_LIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24209">
        <property type="entry name" value="PROTEIN DA1-RELATED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24209:SF7">
        <property type="entry name" value="PROTEIN DA1-RELATED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12315">
        <property type="entry name" value="DA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00412">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00132">
        <property type="entry name" value="LIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00478">
        <property type="entry name" value="LIM_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50023">
        <property type="entry name" value="LIM_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0440">LIM domain</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="LIM zinc-binding" evidence="5">
        <location>
            <begin position="157"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="513" mass="58386" checksum="ADD2D97BC8BE6F12" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2V4</accession>
    <name>A0A8T0I2V4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G123200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2V4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16057" checksum="1A84D06F136C6FCC" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLHVLSPKRLSSTPTKRALYNNVEDMPSPPPAKIPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4C5</accession>
    <name>A0A8T0I4C5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G181700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cytochrome c oxidase subunit 6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4C5"/>
    <dbReference type="OrthoDB" id="5947505at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.95.10:FF:000002">
        <property type="entry name" value="Cytochrome c oxidase subunit Via"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.95.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001349">
        <property type="entry name" value="Cyt_c_oxidase_su6a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036418">
        <property type="entry name" value="Cyt_c_oxidase_su6a_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504">
        <property type="entry name" value="CYTOCHROME C OXIDASE POLYPEPTIDE VIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11504:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02046">
        <property type="entry name" value="COX6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81411">
        <property type="entry name" value="Mitochondrial cytochrome c oxidase subunit VIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="2" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12484" checksum="A250367E1AC6C8B4" modified="2022-10-12" version="1">MANALRQRLGALLSRPPAPASLHTTGAAVTKRFFASKAHAHDDAEETAKWRSITIAAYVLCIGMGAYILTHEEHGQIERTEYSYLHIRNKEFPWGPDGLFEYKHEDHEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4R3</accession>
    <name>A0A8T0I4R3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G164400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4R3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035825987" evidence="1">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6453" checksum="36DE07DEC98D6377" modified="2022-10-12" version="1">MRPVCILSIGMLFLLWSGVRKMPPFAQCGQVIVKWNCTCCVQTIKYYFLTTEPACY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4Z9</accession>
    <name>A0A8T0I4Z9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">50S ribosomal protein L12, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G033200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1390.10:FF:000001">
        <property type="entry name" value="50S ribosomal protein L7/L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_bL12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_bL12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_bL12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_bL12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_bL12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="39S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987:SF26">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN BL12CX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="Ribosomal protein L7/12, oligomerisation (N-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Large ribosomal subunit protein bL12 oligomerization" evidence="9">
        <location>
            <begin position="60"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL12 C-terminal" evidence="8">
        <location>
            <begin position="117"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="18992" checksum="4370F2D1E829286E" modified="2022-10-12" version="1">MAAMAQASLVSAPGSLGAVSSVARGGEFQSAARVQFGGVRVQLKRRALGVRAAVADMEKLDRLVTEVEGLTLEECRVFTDKLQERLGVTAAAFAPAAGAPAGAAAEAAPAVEEKTEFDLVLEDVPASARIAVIKAVRSLTALGLKEAKDMIEGLPKKVKEGVSKEDAEEAMKSLEAAGAKCSIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I538</accession>
    <name>A0A8T0I538_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G202200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I538"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02970">
        <property type="entry name" value="PRX_like2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000166">
        <property type="entry name" value="Thioredoxin-like protein AAED1, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032801">
        <property type="entry name" value="PXL2A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28630:SF23">
        <property type="entry name" value="THIOREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13911">
        <property type="entry name" value="AhpC-TSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="29443" checksum="262C0C2C18C0D59A" modified="2022-10-12" version="1">MDGMLLRTSVNSFFCHPQAGQQQGKNSDFNNHLASCSSFTPNTISHSLTSRPASSAIISKSKSSQMKRAAGVAYAAVQTGEIVDMSAFESITIYTTDGAPVKFSELWDQKNGKAVVAFLRHFGCPFCWEFAAALREAKPKFDAAGFKLITIGVGPSSKAEVLAERLPFPAECLYADPDRKAYDALGLYHGVARTWLNPASMQIFTRLDKVAEAVKGWNLDVMPDNTSATLQQGGVYVFEGSRVLYARKDESTGDHSKIDDILNSCCSTVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5C6</accession>
    <name>A0A8T0I5C6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G004800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5C6"/>
    <dbReference type="OrthoDB" id="1919377at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008390">
        <property type="entry name" value="AWPM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294:SF5">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05512">
        <property type="entry name" value="AWPM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="18037" checksum="A7C13651EC6BC6C0" modified="2022-10-12" version="1">MAFGISKAMVIPLLVLNFCLYFIAAALAGSILNRNLDANIGADGNNVPIGNVVTPVFIPVTLIACMVGLASCLAGLHHIRTWRMESLAAAAATALIAWLLTLLAMGLAAKEIHTRYGRSKRMKTVEAFMIITALTELLYLLSLYAGKVTREGYATTPANPKYGTPAATAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5E0</accession>
    <name>A0A8T0I5E0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Ubiquinol oxidase</fullName>
            <ecNumber evidence="13">1.10.3.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G169500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 a ubiquinol + O2 = 2 a ubiquinone + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30255"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="EC" id="1.10.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the alternative oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.10.3.11" evidence="13"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5E0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098803">
        <property type="term" value="C:respiratory chain complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009916">
        <property type="term" value="F:alternative oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106292">
        <property type="term" value="F:superoxide-generating NADPH oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102721">
        <property type="term" value="F:ubiquinol:oxygen oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010230">
        <property type="term" value="P:alternative respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01053">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.140">
        <property type="entry name" value="Alternative oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002680">
        <property type="entry name" value="AOX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038659">
        <property type="entry name" value="AOX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803">
        <property type="entry name" value="ALTERNATIVE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31803:SF19">
        <property type="entry name" value="UBIQUINOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01786">
        <property type="entry name" value="AOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0249">Electron transport</keyword>
    <keyword evidence="11 13" id="KW-0408">Iron</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0577643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="477" mass="54899" checksum="363020F3FC602EB3" modified="2022-10-12" version="1">MGSVTAMTSVVATSFVSPCGNLGLRDRWGISSCLLAKRLRLRCLRYDGAKQETGTGRVRRRGLCVARISETEGQTLEQEEAQAREDERTGAGGYKLKENAQPTKPVQLEMETVDDVERPKRIAFNYGFQAKFLRTGPSVPGNVVKLAFENFGREWRSLRRTILFTKLQRIDPSKLSGPLEVVTAYTGRGLFLFLRGLDKFLTLYDGLMELKPLETKGENLEQDELRAALKKLKLSNKAVWDRENARPPVEAPWWILGPYYLLCLMLDVIFDNRPIQRFWFLETVARMPYFSYISMLHLYETLGWWRIGAEVRKVHFAEEWNEMHHLKIMESLGGDLEWGDRFFAQHAAFFYYWVLNVMFLISPKVAYNFSELIEMHAVDTYGEFADANEELLKTLPPSPVAVAYYEGEDLYMYDEFQTSQAPEARRPKINSLYDVFVAISGDEMEHVKTMAACQALNMPVMSPHDRAQRKKEEEVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7S7</accession>
    <name>A0A8T0I7S7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Subtilisin-like protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_4G107000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7S7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02120">
        <property type="entry name" value="PA_subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2310:FF:000001">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000006">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.80:FF:000002">
        <property type="entry name" value="Subtilisin-like protease SBT5.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041469">
        <property type="entry name" value="Subtilisin-like_FN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17766">
        <property type="entry name" value="fn3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036435076" description="Subtilisin-like protease" evidence="9">
        <location>
            <begin position="29"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="11">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="138"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease fibronectin type-III" evidence="12">
        <location>
            <begin position="664"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0579562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="81998" checksum="D1CD7803D7FA6A54" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8L5</accession>
    <name>A0A8T0I8L5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G049000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8L5"/>
    <dbReference type="OrthoDB" id="1916325at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021924">
        <property type="entry name" value="DUF3537"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31963:SF4">
        <property type="entry name" value="GUSTATORY RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31963">
        <property type="entry name" value="RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12056">
        <property type="entry name" value="DUF3537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="499" mass="57049" checksum="DC70345451E830DC" modified="2022-10-12" version="1">MNGGQTEDGSRAPLLGFLTTDLGRGEEVRRDDQSEKSFSHTVRFEDEVGTGPKMRERVVDIDDPKRSRNIMLASVLSHPHDELRYFRNGLRCLGLDQSTKFKVGLSWIVFVLFTFIVPFVNLTHVSCPDCDPQHRHPFEGLVQIAESSLAAVSFLCLSHIVRRHGLRRTLLLDRIVRESVEVRTGYESELHSAFSLLASILLPVATIEIVFRVWWYYYVTVTIPFIEDDRRLSLILNIAFFSSGLLSWLYRTSVFLFTCILFRLMCSLQILRLKGYIKLLGTTPNVSIILTEHMRIRSQLTTISHRFRAFMVLSLFTISFSQVWSLFVLLSSYEKFNFFRAGDLVVCSVVQVTGLMLCLNGASKITHRAQRIIGIVSQWHALATCNPHAVTDSQKNGDDPSQWSTTMRGPAHPHLYNDSSEENDSDEDSPRHSNDVDQYIHDMENFQKRNALVCYLQQAKTGISLYGCVLDRGFLYGMFGCTVSLTLFILDYCLRKLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8X7</accession>
    <name>A0A8T0I8X7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G154800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8X7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="20552" checksum="909BE6698912EA71" modified="2022-10-12" version="1">MEGESSKNSPGATCRETCAKMWEGHMKTARAYVEAERLRVAAMEANLQSNIAIFQAWVYESAMAEPLEDLDCLIEVLEAHSMMENDARENQEFNQQVWLNTREMVNDLEKKVSKAKLGLKKVEDLLTVLESNTESHVNALHEMMNGAGITSSLICVCGDPTCFFPIRDHICSDFESSLWWIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9U5</accession>
    <name>A0A8T0I9U5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G117500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9U5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="402" mass="46394" checksum="CF147C2324151D97" modified="2022-10-12" version="1">MAPRPSRNLKEDATVLGDMKDDVAMDPTLWGNLKDYVAMEIIYAKVPFHEFFQLRLVCKEWNHLAGDRKFLEDHFKEYLVPEPYFYIPGGCEYLDPYPQLVNGRFMNGLLTIDITSEDVGWIGLYNTWKDRGGCFAVNGLIYSETVPSPDYLSRQKKTPEVVQKRAESRRQEVFNIHTRVRHKLPAPQLSTAIPVVGMLVDTSVRPYGFKVIQGCGDLGTQIFDSRTNAWELRPSRLPVGIAARLDSSRSKSYDNPGLCKHGSVNCNGLLFIRTEDCKEILVYNEKEDVWSTLRVPNYFVRRFFSIGSWHGRLFNAGRLGVCGLTWDVVNPSRHKWEPYDQMPADVRDWLACGLNFFLDCTDFSKNYLLICNRRTTEDCKIKIVLYDLATKSWETFTFRFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAQ3</accession>
    <name>A0A8T0IAQ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G140400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAQ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47262">
        <property type="entry name" value="OS02G0132600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47262:SF1">
        <property type="entry name" value="OS02G0132600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="395"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="430"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="465"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="500"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="535"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="570"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="3">
        <location>
            <begin position="692"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="764"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="887" mass="100016" checksum="046A28490AA7A755" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEI5</accession>
    <name>A0A8T0IEI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G240600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035720055" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5771" checksum="2DD3D611A1231070" modified="2022-10-12" version="1">MCTCQVVVCRLCFLGTQTLDTCDLRTKFVTKPDDPCTSILLNMVSFVIRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFB5</accession>
    <name>A0A8T0IFB5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G057300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="215" mass="24319" checksum="6DFECAD0CB0828B3" modified="2022-10-12" version="1">MCYALSHIELTHTDLLPLCATRTSRSRGPYIHRRRLPDIPHLNLSSLSLSLTHTPSPPTQRKTTRQGPFESAPQWQLLLEKRSHSAHQHERHRAVHLAFATPSRNPRSDDFHLPPDQKFPETTSPTLNGAAPLYRRSARSARPPRPCKTLQTLDQTFSTIPAPSLNRKPRENFRSARAGSLTPMHNTAAQAPERCVLTQHQIDEQCTSPRGRHTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFC5</accession>
    <name>A0A8T0IFC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G259400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial phospholipase C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042578">
        <property type="term" value="F:phosphoric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000011">
        <property type="entry name" value="Non-specific phospholipase C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007312">
        <property type="entry name" value="Phosphoesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956:SF1">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31956">
        <property type="entry name" value="NON-SPECIFIC PHOSPHOLIPASE C4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04185">
        <property type="entry name" value="Phosphoesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035739313" evidence="4">
        <location>
            <begin position="28"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="418"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="59348" checksum="641958161DB41FBB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGR1</accession>
    <name>A0A8T0IGR1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G097700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852">
        <property type="entry name" value="OS06G0298400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852:SF2">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="168"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="914"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="648"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="858"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="687"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="861"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="905"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="947" mass="103161" checksum="A2E110BE677C79C2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ34</accession>
    <name>A0A8T0IJ34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic</fullName>
            <ecNumber evidence="9">1.3.1.75</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G126000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>protochlorophyllide a + NADP(+) = 3,8-divinyl protochlorophyllide a + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48884"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58632"/>
            <dbReference type="ChEBI" id="CHEBI:83350"/>
            <dbReference type="EC" id="1.3.1.75"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.75" evidence="9"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033728">
        <property type="term" value="F:3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05243">
        <property type="entry name" value="SDR_a5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044201">
        <property type="entry name" value="DVR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47378">
        <property type="entry name" value="DIVINYL CHLOROPHYLLIDE A 8-VINYL-REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47378:SF1">
        <property type="entry name" value="DIVINYL CHLOROPHYLLIDE A 8-VINYL-REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="12">
        <location>
            <begin position="108"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0583312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="432" mass="45672" checksum="C7909A90C5654B15" modified="2022-10-12" version="1">MSLSVVSSRAASSLLPGAVSSAPSGHGFSQMSSIGYVSKVGNGQALGCKASSEFLGLALKAVRISGGLQKPWVRHLCRAALAPEVEAVVGKQAWRSKSPKDTNVMIVGATGYIGKFVVKEMVKRGYNVIAVAREKSGIGGKADAEQTIKDFPGATVLFADVSDMDSISSALQSSKTNVDVVISCLASRTGGKKDSWKIDYQATRNSLDAGVANGASHFVLLSAICVQKPLLEFQKAKLKFEAELASHGNGLTYSIVRPTAFFKSLGGQVQSVQGGGPYVMFGDGKLCACKPISEADLASFISDCVSDVEKANQMLPIGGPGKALTPLEQGEMLFKIVGKDPKFIKVPIGVMDFVIGVLDNLSKVFPNLEDAAEFGKIGRYYAAESMLVMDPETQKYDADGTPSYGTDTLEAFFDRCVREGMAGQELGDQAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJY5</accession>
    <name>A0A8T0IJY5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G147900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030198">
        <property type="term" value="P:extracellular matrix organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.100.10">
        <property type="entry name" value="Thrombospondin type-1 (TSP1) repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050439">
        <property type="entry name" value="ADAMTS_ADAMTS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000884">
        <property type="entry name" value="TSP1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036383">
        <property type="entry name" value="TSP1_rpt_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723">
        <property type="entry name" value="ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13723:SF281">
        <property type="entry name" value="PAPILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19030">
        <property type="entry name" value="TSP1_ADAMTS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00209">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82895">
        <property type="entry name" value="TSP-1 type 1 repeat"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50092">
        <property type="entry name" value="TSP1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="EGF-like" evidence="4 5">
        <location>
            <begin position="397"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="108"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS01186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0583592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="569" mass="62086" checksum="3DCE3E2C846FC882" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK16</accession>
    <name>A0A8T0IK16_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G186700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK16"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5185" checksum="BA56B025673D214D" modified="2022-10-12" version="1">MTSCCKFPAYCLPLRSQTKQSDCASSVCMFKGTGKSVGCSELASGVALDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK37</accession>
    <name>A0A8T0IK37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G126700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="23"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="996" mass="114327" checksum="D29E8E1196227B75" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKQ7</accession>
    <name>A0A8T0IKQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G137500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF21">
        <property type="entry name" value="PENTACOTRIPEPTIDE-REPEAT REGION OF PRORP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="158"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="229"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="264"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="299"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="334"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="369"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="438"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="510" mass="57575" checksum="FAD6455AB69BD9CB" modified="2022-10-12" version="1">MTLVSSLVVSDSHPMSFSKLGFSGSGVFGSDVELCSVRFVGGVSSRSVLLKRDRDGGEMWVWKGRGGVLVRCGGDEGSDSSVGEAGSKRRPARTDYSGAQRIERAQEATKRRALARGSRKLYTRSLLVSLHERIKQNHWVPALEVFKLVREQEWYVPVLSTYLQLLTLLAKVRQPAEALSLFDSLLEDNLKPTTAIFTALLTVLTKTNHFRKAVVVFESMRLYQGCVPDKYTYTAMIKGCCEAGLYDQARKIFDEMILEGVKPTIVTFNTLIFGYGKSGRFRDIERVLTLMESYGVAPDTVTWNTLIRVFGLHNRITEMEQAYEGILAQGLRPDVVTLNSLISAYGTAGLFEKMRSVTDFMVRYGYPMTTVTYNIVIETYGKAGEIDQMDMAFEKMEAEGVKPNRATFCFILSAYGQHGHWHNVDRVMQQAKEYDAVNTSVYNAAIDAYRRAHNFEEMEKMYDEMKLEGLAPDDVTFSILIDAYKRVMRLEKVQQLQEEWDALTKQSAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKT6</accession>
    <name>A0A8T0IKT6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF4378 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G114600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032795">
        <property type="entry name" value="DUF3741-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025486">
        <property type="entry name" value="DUF4378"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21726:SF61">
        <property type="entry name" value="DNAA INITIATOR-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21726">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P DOWN SYNDROME CRITICAL REGION PROTEIN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14309">
        <property type="entry name" value="DUF4378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14383">
        <property type="entry name" value="VARLMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3741" evidence="3">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4378" evidence="2">
        <location>
            <begin position="874"/>
            <end position="1050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="754"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="427"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="117533" checksum="EFE972C9515F63AF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILE2</accession>
    <name>A0A8T0ILE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CST complex subunit TEN1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G158600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILE2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990879">
        <property type="term" value="C:CST complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042162">
        <property type="term" value="F:telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032211">
        <property type="term" value="P:negative regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029146">
        <property type="entry name" value="Ten1_animal_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33905">
        <property type="entry name" value="CST COMPLEX SUBUNIT TEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33905:SF1">
        <property type="entry name" value="CST COMPLEX SUBUNIT TEN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15490">
        <property type="entry name" value="Ten1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="125" mass="13820" checksum="1EC8F306D8D5F7CB" modified="2022-10-12" version="1">MAMAMVAPVSPGVVVRLHELHSASPYVASDQSLRVLGSLERFDAASGIAVLTDGGSALRVDLQHLRALPLRVGSLFEFIGELEVNPVQELTLKARVGRNVDGMDLRLFDKVLQFRRKFEEEFRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM18</accession>
    <name>A0A8T0IM18_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphatidylinositol-specific phospholipase C X domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G201100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF204">
        <property type="entry name" value="PHOSPHOINOSITIDE PHOSPHOLIPASE C 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatidylinositol-specific phospholipase C X" evidence="3">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0584302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="152" mass="16592" checksum="B19D6C37491305A8" modified="2022-10-12" version="1">MVDEQQRRSGISTLQDVRPDLTAGSAAELLDEATLTNPVSFEKCLIAIKEKAFSSSEYPVCVTLEDHLTSDLQAKVAEMLTRILGESLFYPKTSDPLTEFPSPESLKKRIIVSTKPPKEYLEASAAAKTALKDKGEGAQERRCGAENIKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPP1</accession>
    <name>A0A8T0IPP1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G262300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="605"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="708"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="793"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1276"/>
            <end position="1294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1300"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1386"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1416"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1444"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1497"/>
            <end position="1520"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="192"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="928"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="862"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="877"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0585152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1528" mass="170901" checksum="A95D3D1F92ACB317" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPT4</accession>
    <name>A0A8T0IPT4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G251300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPT4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="8882" checksum="D35B428875DE44B5" modified="2022-10-12" version="1">MLQYNGVSRAESPGQKEEQLDEELLSEHSKTLRQSEFVSALSILYMSQSPEIPPSGELSLVQDWTDYRHEGAACIRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITB8</accession>
    <name>A0A8T0ITB8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G056400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd22009">
        <property type="entry name" value="HMG-box_AtHMGB9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691">
        <property type="entry name" value="HIGH MOBILITY GROUP B PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="4">
        <location>
            <begin position="79"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="340"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="340"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="329"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="462" mass="52118" checksum="7CC3F0C0147884D6" modified="2022-10-12" version="1">MSSLVEMSVAPVEGEGQLEVDQNGDVEQSELQQFGFSSDMHPSNQSGFVTLRDTSSIPGVSMYARQWYPSVYFTHAELVASKEVFFEALDKFHNVLGTRLTKKGRKGKERAAEVKTFQESIAGIPPLGGVAIDLHLLYVEVTNRGGLEKVIKDRKWREVINIFEFPESITSGSYMLRKYYVGLLYYFEQAYFFGKQGPLVPPPMWMPGPLKKSVYSSSRKYPLPDGDPATKSIRKRKILPMQIMPVVDPARMIGMKVQGAIKGKFEQGYLVTVTVGTEMLQGVLYHVPPAQRTPQHVNVPNLEEPFGTQMAISRGDPKAGGSWRKRRRRDETVKKDPNAPRPNKTGYNFFFADQCAKFKAMHPDADKELGRIMGHAWNNLTEEEKLPYREQSMKDKVRYINELQEYRERLRSNEGSAPLEAATISVQENEAGEEESVVDADDGLKDILRISASNATSEFSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUI1</accession>
    <name>A0A8T0IUI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G092400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11960" checksum="51C48C06DBF3773A" modified="2022-10-12" version="1">MYSRPPTHAHRSLRLRMYRFSVISSSWKACHNQTYLACHHNLPYLALAYLHPYLAYLHPTRTYPQLEEQAEREEGAEHTCSSSQLLPSPLAPLTSSPQLLPICL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW69</accession>
    <name>A0A8T0IW69_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GIL1/IRKI C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G128100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056813">
        <property type="entry name" value="GIL1_IRKI_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24994">
        <property type="entry name" value="GIL1_IRKI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIL1/IRKI C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="157" mass="17022" checksum="13A0C6D6EDE418D1" modified="2022-10-12" version="1">MESVVPGGYEEEDEETGADVNTVVGFLVIPGFQVSKSVVKCEVYLRNKNSLDDGKIEEASETPSGTKMKASSQDSVKSFQFEAKSAHGNDTQRRKHEGSLVANKVPREERCFAGTAVAFLEQNETLPTKQRSDSGTLFSLGNVAIRRGFGGSFLVVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXA1</accession>
    <name>A0A8T0IXA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G237300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="6859" checksum="E0F09F4F6CE14BED" modified="2022-10-12" version="1">MMRVNIISRSSVSHHGELLQSVSIKSLKGSGSCRFVVCTLTFNKHRYKLSQIAAVQSLFSCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J094</accession>
    <name>A0A8T0J094_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G018400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J094"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF28">
        <property type="entry name" value="AARF DOMAIN CONTAINING KINASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274591" description="Protein kinase domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="174"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="565" mass="63859" checksum="19CD3B6B4DE13DAC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4M0</accession>
    <name>A0A8T0J4M0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G110200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4M0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="7651" checksum="6AA7FF168B695FA9" modified="2022-10-12" version="1">MAEEVPPAGGAANRNARNNDNIPVPQLHVPAVNIPLQAPVVDDAVLSFLSDLPEQKLSVTQSVIWPKLFCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5N5</accession>
    <name>A0A8T0J5N5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G103200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13335" checksum="4A0E131C7424B67E" modified="2022-10-12" version="1">MSSGMFYPELLPGHFGNSTQQAGDYRLSKECKHLPQPTLPITPAARQPTPTISTVRTPNLLISAFRRPIVQTRLRNTNLRINMPNTAPQPDPGNGYPHNSAEPCPPSADPPTAHDSKRVTVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7P8</accession>
    <name>A0A8T0J7P8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Signal recognition particle 19 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G132300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds directly to 7SL RNA. Mediates binding of SRP54 to the SRP complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of a signal recognition particle complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
            <location evidence="2">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7P8"/>
    <dbReference type="OrthoDB" id="2190947at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006617">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.56.30:FF:000002">
        <property type="entry name" value="Signal recognition particle 19kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="entry name" value="Signal recognition particle, SRP19-like subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17453:SF0">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0733">Signal recognition particle</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="118"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0590878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15344" checksum="8A2991D25D0582DE" modified="2022-10-12" version="1">MEGGLKPDTSRWVVIYPIYINSKKTLAEGRRISALKACENPNVVEIGDCCQYLRLPCAIELDKAYSRDFMQRGRVRVQLKRDDGSLVNPAIPTRKALFLKVAELVPKHHGRSKKQEQSGSASGPSGAPAPKGKGNKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9X1</accession>
    <name>A0A8T0J9X1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G260900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9X1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035789160" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8147" checksum="3F06B5B77CF889B1" modified="2022-10-12" version="1">MIMVVMFLQTIMLQDFCITLGLMPSITRIVYHSDLHIKYMHAHLQSPKKIERARHLTAEGCTGSDRTTAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAG1</accession>
    <name>A0A8T0JAG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G204500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051177">
        <property type="entry name" value="CIK-Related_Protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984:SF3">
        <property type="entry name" value="N-TERMINAL KINASE-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12984">
        <property type="entry name" value="SCY1-RELATED S/T PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="594"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="638"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="597"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="756"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="804" mass="86517" checksum="FDA57E507C9D3F1B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBW3</accession>
    <name>A0A8T0JBW3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G281600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14399">
        <property type="entry name" value="UBA_PLICs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16106">
        <property type="entry name" value="Ubl_Dsk2p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000005">
        <property type="entry name" value="Ubiquitin domain-containing protein DSK2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015496">
        <property type="entry name" value="Ubiquilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677:SF3">
        <property type="entry name" value="FI07626P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10677">
        <property type="entry name" value="UBIQUILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23195">
        <property type="entry name" value="UBQLN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="3">
        <location>
            <begin position="135"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="2">
        <location>
            <begin position="623"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="420"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="666" mass="69832" checksum="25B522DD26B9563D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JEZ6</accession>
    <name>A0A8T0JEZ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G338300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JEZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="4558" checksum="56E75BD2D592A02B" modified="2022-10-12" version="1">MSHNFVICRNFQWLSDISWFCMQLPRCYDLIYNRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3Y1</accession>
    <name>A0A8T0G3Y1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G026200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3Y1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000055">
        <property type="entry name" value="Serine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="entry name" value="Serine-tRNA synthetase, tRNA binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="SERYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="tRNA-binding arm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="12">
        <location>
            <begin position="222"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="116"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="345"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="361"/>
            <end position="364"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="432"/>
            <end position="435"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="485"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for serine binding" evidence="8">
        <location>
            <position position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001529-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0553625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="532" mass="58261" checksum="867B7FAF53289420" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G494</accession>
    <name>A0A8T0G494_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Floricaula/leafy-like transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G059600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probable transcription factor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the FLO/LFY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G494"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002910">
        <property type="entry name" value="FLO_LFY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035079">
        <property type="entry name" value="LFY_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36079">
        <property type="entry name" value="PROTEIN LEAFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36079:SF1">
        <property type="entry name" value="PROTEIN LEAFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01698">
        <property type="entry name" value="SAM_LFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Floricaula/Leafy protein SAM" evidence="3">
        <location>
            <begin position="153"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0554063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="276" mass="31012" checksum="5E9C8B04190E1D0C" modified="2022-10-12" version="1">MVRVKGGEWGHVSVVKEPAKHGMAWHVKCSHCGKVFQGNAMRIRSHLLGHPEKVSGCPACPPEAREELRLSYLAKSQVERKKRQGRALKTSRASQQSLENAQQRDSVIDLQRNGEKLSVEQALRSMVFQGSGLPAAFVTLSPIKSMVPNTADVADLESFLDGFGIREETISKIKEMGFTGKTFMSNLDELLTLLDSIKQHCQLTLGEEWGIKGAAKKWQREHGIVNLQPEMEKWQDPESKSTPGCKEEVLNLRMYLTLIYFKVSSAFRARVFLFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5Z1</accession>
    <name>A0A8T0G5Z1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G077700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5Z1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="24083" checksum="336BE96C192F04D3" modified="2022-10-12" version="1">MARRKSVSDVTETGLPSILERSPLLDRREIRSFTFTATESKSKSVSVYKLPSNKSNSRTRNAPHNSSKAAAQPLKAITERQTTNLVSSLERTRSVPLQWYNSSPQYIPSYRSSPAFRSSPQYRVNPVVRFDDRLLPERMNYGIAGYNTSRPRSFPGVGGRKRGLVYRRPRTLQIWRLWTKRFKERMTRIRVRSACSRLMMRFRRRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7C2</accession>
    <name>A0A8T0G7C2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G153000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7C2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11468" checksum="1678D9AE7CFACD25" modified="2022-10-12" version="1">MHSKSRSNQNAEQSIITCQQKSILSIQKHCIRPKNCTYPKKSLSFGTTTLPQHFQYGFNPPRLRFSMCNKQTSRNRSSCMNWHILSYISSSPSSEQLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAF3</accession>
    <name>A0A8T0GAF3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">starch synthase</fullName>
            <ecNumber evidence="6">2.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_11G027000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Amyloplast</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="6"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009501">
        <property type="term" value="C:amyloplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010021">
        <property type="term" value="P:amylopectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000048">
        <property type="entry name" value="Starch synthase, chloroplastic/amyloplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825">
        <property type="entry name" value="GRANULE-BOUND STARCH SYNTHASE 1, CHLOROPLASTIC/AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45825:SF2">
        <property type="entry name" value="STARCH SYNTHASE 2, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13692">
        <property type="entry name" value="Glyco_trans_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0035">Amyloplast</keyword>
    <keyword evidence="7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Starch synthase catalytic" evidence="15">
        <location>
            <begin position="219"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="96"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="104"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="169"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0556111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="709" mass="77616" checksum="A9940B5E4E7860CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH66</accession>
    <name>A0A8T0GH66_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G054400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="254"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="37179" checksum="F0CE87BDEBC409A6" modified="2022-10-12" version="1">MDTCKWKITYNNPNHCSMMELAHTPTRPPWRPAASSITANLDLDVPPPQWSSRKSQKSVELTIPPQYMSATDLIAAMPKRHRMPKPQSLSNALAVEEPRVYPKTPWAPSLTSQLEAAEFGKPSRRSSEHTPKSVLDHAKSTSSDARSRSNTGKHGSQLASPPSAARSLLNSAAQSERDFGGSERSFPIASPRHKRSHQSSPAMSQQGSPPRKNASSNDRASPASPAGSARSPERSPGHSPPYSESGHNSRHRTTATNSGLASVNDTSVSQSTNPRSSRYDTRGSSSRMTTTDTHNNNLPSRGTTGGSVRSMSACSSVTHRSMEGSPASGRCSPPTPASPSSPTYSPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHC2</accession>
    <name>A0A8T0GHC2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exportin-1/Importin-beta-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G149800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF54">
        <property type="entry name" value="NUCLEAR TRANSPORT RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1014" mass="109085" checksum="97B5FC3382DB1215" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHQ0</accession>
    <name>A0A8T0GHQ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G071600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="145"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="497" mass="55793" checksum="64820D7458E2B85B" modified="2022-10-12" version="1">MMSFSVGRREEKMAKSVMRYERKSNGGVKGAGVGRGGAPQYRGYEGYGHHYHQHQHQQQMQQQQEQQHHQYQQYQHHHHYHHHQHYQVGSDGGSAFESSREAFKKATQVLVGRGSSGGGGMDKGEKTGQPMMAAQGGVSSDVSAMPVWTSLPKDLVEKVFAFLPLHSLFQARCVCKCWKNVGFSNNLVKLRAEAPDSPPYFPVYLSKEVDRRWCAYDHVQNKWLHLPPLTFLPKEAKHILAGDGGLLCLSESPSSALNFVCNPVTGTFKKVPSLSQDYEPGITHMVVNGKSHGFKMIVTLTHYLESTHVFESRQNSWQATSCLPPHFLLWGRRSSAFCKGFLYCVALEIGGMNMEGLIAYDVKSGVWTEVHELPRGMRDDPYVLSCGGRVLVVAAQKNTNGRLTSIRIVEFEPVSKRFLEVTEMPQNVMLDVFKCRGGWKPVAYGDRICVASKKTLSVAVYDMVRRSWHELPRCPLPVDTKVDVATFCYGPSLQSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ96</accession>
    <name>A0A8T0GJ96_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G113800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ96"/>
    <dbReference type="OrthoDB" id="3592703at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034256">
        <property type="term" value="F:chlorophyll(ide) b reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010304">
        <property type="term" value="P:PSII associated light-harvesting complex II catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052625">
        <property type="entry name" value="Chl_b_Red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314:SF26">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314">
        <property type="entry name" value="NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="368" mass="39601" checksum="939CEEF7CE4ABE10" modified="2022-10-12" version="1">MMAMATAAGTVQLIALSPTRYQVGAGRDVCMRRSWSRRDHGHRWHKDWCTGGAPILSHAKIRVGDREGPKALVRAEYGDEKKGVVITGGTKGLGFSLAREFLAANAKVVICGRNEDQLNAAISSLQTEFGGSAIEGVRCDVSSASDVAALASFAKEKLGTIHFWINNAGEVTSKKLLADVDAAEIVRVSGTNVVGSLLCCREAIRLMRLQEPSSESSYHIFNMGFSRWGASFTKSACTHKSTKVALTQLTRSLSEELQAAGLSSIGVHNLSPGMVLTDLLLKDSTPVARRFFNTLAEEPETVAKDLVPRILGTRGTGQSIECLSPASAFFKVAFGFPQIISGGRFFDKDGNRVMVSGNRYQENGVKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKP9</accession>
    <name>A0A8T0GKP9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G114600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035897425" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="78" mass="8923" checksum="60BEA7117936F49A" modified="2022-10-12" version="1">MPYIFFLVSVAVYSQILLQSVCRYLFGCLVPGDRGQCYISVAIGKRLDSVQIEVYRFCVQIRVQMGESSRVTCVKDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKR9</accession>
    <name>A0A8T0GKR9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G156000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKR9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="6735" checksum="6674313D9C3C2401" modified="2022-10-12" version="1">MHSPMSRRLGSPFGSLWCCGFRRSPTSGISRPGLSAIKKNGAVFEGGGHSIYSGRFDSIFVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMI7</accession>
    <name>A0A8T0GMI7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G104500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF184">
        <property type="entry name" value="EXOSTOSIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Exostosin GT47" evidence="5">
        <location>
            <begin position="72"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="38644" checksum="80882FB65DDEB76D" modified="2022-10-12" version="1">MVWFKWRATDYRIQSSNGTATTPEYSFLVSLHAFSMKHSKTPFINSGVSPASKADDGERFNWFVMSDTAAPARLNVYVYEMPAKCTTDLLWLFQNSHEQTVNLTSSGSPVHRLIQQHSVDFWLYSDLMALEDKRLVRSVRRVSNQAQADVFYIPFFTTIPFFLLSRSQSKLLYKEAVNWITAQPAWQRSGGRDHVLPVHHPWSMKSHRRFLKAAIWLLPDLDSSGNWYKEGEVSLEKDVVMPYVANVRACDAPCLAISSSLRKTLRFFRGRIVRNSGGRIRAKLAAVLRDEKGVVIQEGSSGVEGNAATELGMRRYLTAFFFLSKNQMLNLLQFNGSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMQ7</accession>
    <name>A0A8T0GMQ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G170900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="268"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="45302" checksum="35E6C0DC5BE1C834" modified="2022-10-12" version="1">MCIDGVGGMKKYARLRQECSEFDNALYDATPEVSFNDESRANGESASPKRGDSPPTVVRSSQTGLTSGLAGAFKKLGSFREVSAARRNTETTSQWQGGPGTNNGSRSASARWPGNAQEEASESGRWVNVETASLSGRWGSVSTSDHWEDATQQGLNSFRDSLSLSRSGRLMQEGEPWTAPKPSEPIHRQPSPRDAAAQPPLASTNANPSDKTFGAAVQQNISMKETQGWLASVKRPLQPRKPPSTFEDPHEFNWRAATSTNGRERDPSSTSSRKTPTTISQSMRYDRLKTIDLVENPSYGDHRNGTGNHSIMQKAASMREGGAHSDAIMAMARAYSEKHGVPQAILECVACGRALGVIVQGDPANDTSFCQSCRPHAIGAWMYHTKAPESGKSKRKGMMHFCKKILRMGKKPNKSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN04</accession>
    <name>A0A8T0GN04_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G117700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050648">
        <property type="entry name" value="F-box_LRR-repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13382">
        <property type="entry name" value="MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="10"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="336"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="920" mass="100907" checksum="2CBB1E48494E85E1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN54</accession>
    <name>A0A8T0GN54_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoribosylaminoimidazole carboxylase</fullName>
            <ecNumber evidence="4">4.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">AIR carboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_9G027800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H(+) = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + CO2</text>
            <dbReference type="Rhea" id="RHEA:10792"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="EC" id="4.1.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.21" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN54"/>
    <dbReference type="OrthoDB" id="15425at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1970:FF:000013">
        <property type="entry name" value="Phosphoribosylaminoimidazole carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.20:FF:000037">
        <property type="entry name" value="Phosphoribosylaminoimidazole carboxylase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054350">
        <property type="entry name" value="PurT/PurK_preATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004679">
        <property type="entry name" value="PRK06019.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609:SF5">
        <property type="entry name" value="PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11609">
        <property type="entry name" value="PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22660">
        <property type="entry name" value="RS_preATP-grasp-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52255">
        <property type="entry name" value="N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="PreATP-grasp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="Rudiment single hybrid motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="12">
        <location>
            <begin position="225"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0560981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="703" mass="75054" checksum="A883712BD7968898" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPM8</accession>
    <name>A0A8T0GPM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(P)-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G021100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47711">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 16, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47711:SF2">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 16, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="167"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="412"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="526"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="554"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="587" mass="61567" checksum="FADE60FF14853A92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPZ7</accession>
    <name>A0A8T0GPZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G083300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093">
        <property type="entry name" value="ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46093:SF4">
        <property type="entry name" value="GALACTOSE OXIDASE_KELCH REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="683"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="770"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="958"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="688"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1032" mass="112366" checksum="6825B59BC6FF71B5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTF2</accession>
    <name>A0A8T0GTF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G065000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTF2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035871146" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7879" checksum="788303F5B0733829" modified="2022-10-12" version="1">MFLCSGIAFGLHFICRFCIFPTSGVIVEVYEIRSGNCVGWETDERLNFRGCLYRLVASCKRIGLHWSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU83</accession>
    <name>A0A8T0GU83_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G105100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU83"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035767065" evidence="2">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="350"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="362" mass="40619" checksum="F2FA02DE7E600B71" modified="2022-10-12" version="1">MCRNFTTIATFVLTDLVHLLQTLRRGLNFPPEGSSTMATLQKPGKEITPTEKAEIGAETAKLEGKGPAGQATEAVKNVVTGRDDGPSAAVVDRGRSNNGFGAHHHHDNGTLGHTEEEFARLRTRTQVTHEGEAYCPNPNIKHLPREFETRVTVIQRYPEMRTVEKTDFVKEIHHEERTIIVPKTRVIMDEIEHVDRVPVVRQVPKTRIEIYHRVVTEEREVTDMVPIIEYMDVPRIEQVPRVITEDVEERITVPVVREVPVTRMVEVPTGNYCEAPAGEFINPGHFNLLGHKHRRHKSKTHSGGLLSKLKSSSSSSSSDDEKTASNSLEPHVHHHADGTTTVDQVSPSASKRKSLLQRIIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUE6</accession>
    <name>A0A8T0GUE6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G023600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="304" mass="33465" checksum="835D334EBAA9DD73" modified="2022-10-12" version="1">MPRLRLVKVSLQDMNPRQQCRNIVPAAWPAASRTHLSITFGPPRSTTIMGAVLTLPASFKFSHSAAHLLVSHPPLSPAFIASGVARTTLYTSIQPSPALLALIRMSATTPAEAVSSQITDEPVPSNERVPSNEPLPPKAETIHLGNLAADIVPHILNLYNCTATAADYEMYDLKATFEDPVMQAHGVKQIKSAFYSIPKVFKEAKMVEYTVTEVESAPNSGEISIDNLQRYKLGSKTIDMISLIKLQVENGKVVRHVDMWNKKPLLDRDTVKVPLMGRLVEKLRRGNMLVTHLFMGGKDPKPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWY1</accession>
    <name>A0A8T0GWY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G129100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF116">
        <property type="entry name" value="F21J9.27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="42"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="449" mass="49718" checksum="497BFC1716676176" modified="2022-10-12" version="1">MKSGARLQVQVLRRWCSSSSASVDASEQSLIAWVREQGGRVGALQVGESGHGGWGLRTTDAVRAGESLIALPPHLPLSVQTSDPVLLALFDRVPEELWTVKLGLKLLAERTRFQTSQWRPYIQNLPKRFTVPIFYSSEEIQALQYVPLMHQVQKRIRFLSEFASETMPNVIGQGPQPDHPFKKHQVLPHALAWSMAAVSSRAFHVHKSGGGSSLLPLVDMCNHSFAPTGRLVQHSSSPQSLPVLEVVAEKDLDEGEDVFLNYGSLSNDILLLDYGFVLPNNPNDRVELRYDGQLLDTACLVAKVDSLSSFKHPAQWQQELLERLQLYGPGASQSVTLGGTELVEGRLLAAVRLMHAQDSNTLIDVDLKALQIWDRTPPLGVMNERRAIRTLIGLGMLALTAFPTVIQEDESELVKGGISDNLRIATQFRILKKHLLLETIKGLKAKYPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXI3</accession>
    <name>A0A8T0GXI3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G113800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="19790" checksum="4D889FCD1BD876A7" modified="2022-10-12" version="1">MMAAFQCEDLREDRREVFEGSTLSLLGSSTYFTPTQTNFAPDAELPASTSTVPSSVYSSTRIQQQISERSDYVGSDAGYFEGEASRDFWSEFYSEPAMDQRGVDEINQEVDDDQMGRPVMESRKRHKGLLGECFWQFLMISTLVPRTSWGKHTSEMRRRGVFTHVQKGEAAEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYY8</accession>
    <name>A0A8T0GYY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G023000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="64"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1206" mass="134982" checksum="FEF129F631E439E9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ87</accession>
    <name>A0A8T0GZ87_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G037800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GEM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ87"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd13222">
        <property type="entry name" value="PH-GRAM_GEM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037848">
        <property type="entry name" value="GEM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31969">
        <property type="entry name" value="GEM-LIKE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GRAM" evidence="3">
        <location>
            <begin position="212"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="355"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="42562" checksum="22D51AF109C1FCFA" modified="2022-10-12" version="1">MSYGYPNQGPPPSYNSTFDDGEPLFTSPPEERYPSMKHTPYQHSTSIFGAPPMGEPSEPSAHPDNKTAATQTAGPSSVTGGPSAGGYNRQSTFENPTASWSGGAHDASPGAAHYASTPSAYQQQTASQPGVAGTVPAGVQPGSPYVQTQSVPATGTSPLNSIVENFNKYMGKAEVLAGNIWSHMKTNPSVLDAAQGRMSQGFKLVQEGGFEGLYKSSFGFANGEQLRKTYACYLSTSTGPVAGTLYISNLKFAFCSDRPLAYQSAPGQQAWSYYKMVVPLDKVKEIVPSFNENKPQEKYIQIVTVDGHDFWFMGFVNYEKGVTNMQLALRHIGVIDPNGGLKAPWAGMSVPGMKKTAAQQPPVNPTVSGHNPATGGTANYNPNANYNPNAPNPYTSNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZF8</accession>
    <name>A0A8T0GZF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G036600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0563504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1036" mass="115403" checksum="23A7A2E4E8B3DABC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZH3</accession>
    <name>A0A8T0GZH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNL-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G043300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050821">
        <property type="term" value="P:protein stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024158">
        <property type="entry name" value="Mt_import_TIM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007853">
        <property type="entry name" value="Znf_DNL-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922">
        <property type="entry name" value="DNL-TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20922:SF19">
        <property type="entry name" value="F24J5.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05180">
        <property type="entry name" value="zf-DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51501">
        <property type="entry name" value="ZF_DNL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DNL-type" evidence="2">
        <location>
            <begin position="121"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21028" checksum="36DE4EDBAAFCDE12" modified="2022-10-12" version="1">MVIGTMAMTQVSGITCPQSVSRSCCNGRLQQPVVVVSGIGSSRMDSTLRFARLSYNSGASHIKAGLNGFTTLGNRCQRRTCKGRVSCQLGGAASSREDEIGPDANVPSMSDGTSVQFDLNLPRRSTLLEFTCNVCKARTQRMINPDAFRRGTIYVQCGSCEVYHQLVDNLNLVKEYDFKNEVDPSMRNDLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3P1</accession>
    <name>A0A8T0H3P1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">IMS import disulfide relay-system CHCH-CHCH-like Cx9C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G133700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3P1"/>
    <dbReference type="OrthoDB" id="494426at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031731">
        <property type="entry name" value="CX9C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009069">
        <property type="entry name" value="Cys_alpha_HP_mot_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017264">
        <property type="entry name" value="Ribosomal_mS37_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066">
        <property type="entry name" value="37S RIBOSOMAL PROTEIN MRP10, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28066:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN MS37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16860">
        <property type="entry name" value="CX9C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47072">
        <property type="entry name" value="Cysteine alpha-hairpin motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IMS import disulfide relay-system CHCH-CHCH-like Cx9C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="82" mass="9549" checksum="806D02A11E287AE9" modified="2022-10-12" version="1">MGRKAGVMRVNPKTLTRKTLPCFQEMLIYLSCVQKFNYDDDKCATEKRALNMCMELQSKQPKQGSTINYHLQRISKMMKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H446</accession>
    <name>A0A8T0H446_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G148000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H446"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044841">
        <property type="entry name" value="LUX/BOA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442:SF29">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31442">
        <property type="entry name" value="HOMEODOMAIN-LIKE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="302"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="127"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="453"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="127"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="245"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="273"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0564888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="55066" checksum="BBAC25856F0B2EFA" modified="2022-10-12" version="1">MMTKDDDRVLEKDDDQVSDWTKGLPSNEELTPLSHTLISRILSSAFRIKHDDPMTAEDVQRESQATLRNLFNQKSTPSFDAFPAFQEEEDAGGYGYGREGRRVEEEFRGKRRVEDDFRGVRAEDEFRDEFRGNQRVEDREDSRGIRRAEVRRDGRPHAVEDRMDYRGASRLEIPRLPSAGSGTDTTGQEMGGVKSNVGVGGPRVQGVQSPAMNAATNSGREYSSAPTKPGNDTNNLEDRAERPGQSPSPFMTNALSYGPYESRGEAGSYANGKDVESSRGADLEPEDANSAGEPANSNEDPNAKRTRLVWTPQLHKRFVEAVGHLGIKNAVPKTIMQLMNVEGLKRENVASHLQKYRLYLKRMQGLSSDEPSASDYLFASTPLPPGMSPHFMPNSANRDDVGGVPFPTPILPMGFPGLVRPGPFGGYEHLPYGAMAGGYMQQTPMLDPRMAVNVSENESRSHAGGSRHVNHRSQSHQNQSNSSSQCELPLFPTNGNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H477</accession>
    <name>A0A8T0H477_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G090100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H477"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766">
        <property type="entry name" value="PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766:SF30">
        <property type="entry name" value="TIR-NBS TYPE DISEASE RESISTANCE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="550" mass="63278" checksum="0DD29E911A5F0F4C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H523</accession>
    <name>A0A8T0H523_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G110900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H523"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="152" mass="16847" checksum="16E345D80E90AF56" modified="2022-10-12" version="1">MSLTPHLSTWVLKWHLGKITHFPVAKVASSGAICEGDSLLTSSVLTYWSSSSQCSQLPVNTLSERVANIAFLSLVDLAFARLCQGPSRIEVEVVTAKELLMMPMPQYPVFSGASRAKDDKDAHHELFYSSFEESLSVRWSSMPKRTSKTLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6B5</accession>
    <name>A0A8T0H6B5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G009100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6B5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034511">
        <property type="term" value="F:U3 snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039241">
        <property type="entry name" value="Rrp9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19865:SF0">
        <property type="entry name" value="U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="220"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="297"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="389"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="522" mass="57120" checksum="AD6681868D3D55CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6G9</accession>
    <name>A0A8T0H6G9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">S-protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G142500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant self-incompatibility (S1) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060320">
        <property type="term" value="P:rejection of self pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010264">
        <property type="entry name" value="Self-incomp_S1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05938">
        <property type="entry name" value="Self-incomp_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0713">Self-incompatibility</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0567551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16657" checksum="DBD6D15BB2CD1887" modified="2022-10-12" version="1">MANYSFSNRVYLLVILVVLEFAVIAFGAREVSFTIVNQIVQEPSAVQVDCWYKNREIAIPERTLRTLEYVQFGGFTPNFWGTTWFNCYFTWGARTAAFEVWIDRFWPKKRPCSLCSWTVRADGFTEYDASPGGGLPVVAHYNWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6Y7</accession>
    <name>A0A8T0H6Y7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G113100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Secreted</location>
            <location evidence="1 9">Extracellular space</location>
            <location evidence="1 9">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6Y7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0052">Apoplast</keyword>
    <keyword evidence="6 7 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035961070" description="Germin-like protein" evidence="9">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="10">
        <location>
            <begin position="47"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0567133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="21700" checksum="BE9C1216D82E2C47" modified="2022-10-12" version="1">MARFAFAVLVTFAVILVAQASDPELTTDFFVPEGVNKTTLTADYFTSTVLRGGVTVVAPAKIAVKRITSALDSLPSLTGLGVSSALIKYLPGGINPHHTHPRGTEILYLLEGTLTVGLVDTTNKFFTKVLEAGDVFVFPKGLVHYQINLGKKPASAYVAFSSSNPGTVSLPITLFGSGIPDDVHKAAFKVDGYVVDKLQLPFNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H746</accession>
    <name>A0A8T0H746_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G030200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H746"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11792" checksum="9451980DBDB0D08D" modified="2022-10-12" version="1">MIAKRTTHASEAQCLRMHVSHPHLLVRIWEMIRCGKDLGTTTTTSLPLSRTHLRSVNKTATASNEEAGKTGNGFERNKKGGFVPHCPSSQKQKICDVSLPDDTLILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7L0</accession>
    <name>A0A8T0H7L0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G130300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the plant self-incompatibility (S1) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060320">
        <property type="term" value="P:rejection of self pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010264">
        <property type="entry name" value="Self-incomp_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232:SF18">
        <property type="entry name" value="S-PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05938">
        <property type="entry name" value="Self-incomp_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0713">Self-incompatibility</keyword>
    <keyword evidence="5 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035963136" description="S-protein homolog" evidence="6">
        <location>
            <begin position="24"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0567373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16707" checksum="FAC805DD9EF99645" modified="2022-10-12" version="1">MATMRKLFMSLLLLFSLTLRMQAYYVRSGSCSVDVVNDMKTPIDVNCWSGDDDLGYVTVRPLCDYHFEFDPNIFGTTLFLCKFEWGVRRQQIKVWKGDAYKDQLQCSDDGPCVWKVTTRGFYWSNQTEGDAFSWTFYTDWSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBT8</accession>
    <name>A0A8T0HBT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G081900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBT8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9133" checksum="9FAA9A54516CF645" modified="2022-10-12" version="1">MIGVHDSSTSSLLMLKLQREIAAGFGCAMRTSFKAGASILTPSINVEILVSSTGFIPPSRISSSICSKLLAVAAQRWPVLRLASKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCC3</accession>
    <name>A0A8T0HCC3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G084400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="28931" checksum="C2F78512D935E289" modified="2022-10-12" version="1">MSKIAGSILRYFKPLEIDFLDLCEQNLQSIADLVSRGSLLNRRQCLDLSTKLSQTTQNIRQLVDQCGGGSTNLFRSALENLFRYLEKAKVLVSKCGDEHWWVAATFQIRNENAFREILLEVSLCYNTIYELAKSGSEKSDVLPDDLRQPPAAVFAPAIARDVQKDQQDIQQRLEELANSPSSVQLQGLPLTEEVALKAQSLARYLLLRMRYASQQSLATTLDTFCEILWRKDTEPPGTWGNSYYLGGGATEGRCLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGR6</accession>
    <name>A0A8T0HGR6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G005400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGR6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11875" checksum="058F583375281B04" modified="2022-10-12" version="1">MSVPSPAERTYLKLIPALSRALGLQGRISVAANRFSPHPSQYVSIRFVLSCAGFHPEAGHAASLSRSGHHQRLERGQNSSFRAVYPTSCHRYCLFSIDAVNLCTDSYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIM1</accession>
    <name>A0A8T0HIM1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G176000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7359" checksum="5C8252F556F43692" modified="2022-10-12" version="1">MHYEEGEREHDEGGDINTAPTLQPQDGLARRCSRAELRDGGRREENGRGRAPAREGVGAGDPLFAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ93</accession>
    <name>A0A8T0HJ93_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">glucan endo-1,3-beta-D-glucosidase</fullName>
            <ecNumber evidence="4">3.2.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_6G193000</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of (1-&gt;3)-beta-D-glucosidic linkages in (1-&gt;3)-beta-D-glucans.</text>
            <dbReference type="EC" id="3.2.1.39"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
            <topology evidence="2">GPI-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.39" evidence="4"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ93"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009506">
        <property type="term" value="C:plasmodesma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098552">
        <property type="term" value="C:side of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042973">
        <property type="term" value="F:glucan endo-1,3-beta-D-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000005">
        <property type="entry name" value="Glucan endo-1,3-beta-glucosidase 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1040:FF:000001">
        <property type="entry name" value="Glucan endo-1,3-beta-glucosidase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044965">
        <property type="entry name" value="Glyco_hydro_17_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012946">
        <property type="entry name" value="X8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32227">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07983">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00768">
        <property type="entry name" value="X8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00587">
        <property type="entry name" value="GLYCOSYL_HYDROL_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12 14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0336">GPI-anchor</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 15" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035870697" description="glucan endo-1,3-beta-D-glucosidase" evidence="15">
        <location>
            <begin position="32"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="X8" evidence="16">
        <location>
            <begin position="452"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0570863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="538" mass="56607" checksum="76379485E9F9A0B9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLD2</accession>
    <name>A0A8T0HLD2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG029900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLD2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="249" mass="28522" checksum="DC9656B794EB9443" modified="2022-10-12" version="1">MPSSEERTCYSEEIDGDHMASTKELTSKSFDGNETMNAGTEEVPYRSRETITKQQGYGDAVDVVKCEKQQTIDRPFSDGNGDLREAGPSEPDEDRFRYNIFGPPPPWLMETGYDRDDLRNFRIANRRERNKELRLSRLVEEQAKESVAENEVCDSLELDAYDMGTPQPYVIQDSNASSNKDREKGEAEGEWPAYIIAEHIRRRPKGRLIDLHPLEVAEIMEMKKSRPKKYSLKERFGKFLQNDGGGSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLP7</accession>
    <name>A0A8T0HLP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG036200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8978" checksum="1F239502DFCA4AEA" modified="2022-10-12" version="1" fragment="single">ALWKFLWRYWFPFNLQRCRGFLIVTGFLHVQTLLILVDSVCWLGIGGRHRTASRTASILPYCPKRVTEYLERCCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLS1</accession>
    <name>A0A8T0HLS1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG040700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="167" mass="18755" checksum="9841C8FDF9C539A3" modified="2022-10-12" version="1">MEAMAEAICPKEEDRRNEEHVQLLSCLAASCYAQGSRSCRKQLFFMSVMQKRILNPKSKGSGFCRPTRGSQTPPRATASLEQPPPPTPQDPFTPTLQDPPLPVTPSFLVRRVGAPSPSRAHSLSLPPELLRRWRPPKVSGFGGRVSRPWRLLQHCFFEALFSEGFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HME1</accession>
    <name>A0A8T0HME1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG058000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HME1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12134" checksum="C73153F54203E582" modified="2022-10-12" version="1">MNVTQQASPNSNYKPPFRLGQPLESATQTSDLKLSMRFRRLPRSREKGSPSPNPSNLERSQPIVVYFLRPSSSNSHFLLLRRFFSTQQALLCSLNQQPHTFTLLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMG2</accession>
    <name>A0A8T0HMG2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG051200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19513" checksum="9A8CED58E811BD5B" modified="2022-10-12" version="1">MLFLHFHVGLWSKMPLGELKPLLTHILPAGVMERLSFVYSRSDLIDRENFPWSYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRKTPNCMCYIPWPFQGHLNFPNDDGVIPNIATDILPLVYPLHKYGSVPEYMAQAWRPGQVHWVIEAARKFGRARVDWTEVCWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNH9</accession>
    <name>A0A8T0HNH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG089200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="18522" checksum="D151CA096C5777A6" modified="2022-10-12" version="1" fragment="single">LSPAKALRSPLQLTVLHEADVLGVDAEALAAGVDAVLADHSARVAAHPAGARPGAVDLGVRVPDRFVTHGGQTPSVRDDGAVRAAAATPRSVERRKYQALTLACMGFTTRNATKTTVEIFAPGNKVVGLDFGSLWVFGVLKVVSFVDGFVSLGNGMVWVLCRSRISMQWRWSICA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNI5</accession>
    <name>A0A8T0HNI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG092900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11590" checksum="9145E6DE2ECBE9E5" modified="2022-10-12" version="1">MRNGSETLLLNMMSLSTTDPTPTPISSLENPNRLQPHSSNRNYFLNITTTTQRYMKCLQSNPLHRIQIQTSTSLTTSSRSAKQSTINTSLSAHQTRSCTFEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP86</accession>
    <name>A0A8T0HP86_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG109300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="7058" checksum="AE8077A5FC8E7A7E" modified="2022-10-12" version="1">MMIHTQTMRTMRTMRMISRLKIVQMILLKTEMKKMLGSLLKCSLCSFSRTRKTCPTKRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPM7</accession>
    <name>A0A8T0HPM7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG129100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7224" checksum="7D9CCF797AE4C7B9" modified="2022-10-12" version="1">MRIPVHRDTKLHVRTICNECSILIVGSSKTVDGSRPATPSDVDVALGAERTFSEGDAPAEAAGHITEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT59</accession>
    <name>A0A8T0HT59_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG244900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045123">
        <property type="entry name" value="METTL14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107:SF0">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51592">
        <property type="entry name" value="SAM_MTA70L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="167"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="348"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="551"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="633"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="887"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="939"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1250"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1501"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1814"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
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            <begin position="51"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="167"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
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            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
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            <begin position="233"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
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            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="581"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="663"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="735"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="964"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1003"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1021"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1057"/>
            <end position="1120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1128"/>
            <end position="1166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1251"/>
            <end position="1262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1263"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1312"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1325"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1832"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1891"/>
            <end position="1900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0574220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1950" mass="220400" checksum="AF85FB51DE288C79" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV25</accession>
    <name>A0A8T0HV25_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">JAB1/MPN/MOV34 metalloenzyme domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG300300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JAB1/MPN/MOV34 metalloenzyme" evidence="1">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9540" checksum="C262C2AC8C391E33" modified="2022-10-12" version="1">MATPLRSFVQAAQVEAEVVPLRVVQIEGLVALKIIKHCKECMPALVTGQLLGLDIGSILEVTNCFPFPVCFYERFLAFNCERSVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVH5</accession>
    <name>A0A8T0HVH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-phosphoglycerate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG311800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33477:SF2">
        <property type="entry name" value="2-PHOSPHOGLYCERATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33477">
        <property type="entry name" value="P-LOOP NTPASE DOMAIN-CONTAINING PROTEIN LPA1 HOMOLOG 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="46632" checksum="45667B6665CB644F" modified="2022-10-12" version="1">MASVSFAKEKGEAAGGEAGGSGSGAGAGVAEGSSRGSKVEVDAPVTEPTVSRPSRGAASKYDFVKVKVWLGTNADHYYVLSRFLVSRMLLVTKIPNHAAIKISLELKKLLIDNSLLDVSQLDLEANLFKLMERRGYGAEYIERYKMMTRFHHQRIPLVILVCGTACVGKSTIATQIAQRLNIPNVLQTDMVYELLRTSTEAPLASTPVWGRDIASAEELVTEFCRECRIVRKGLDGDLTKAMKDGKPVIIEGLHLDPSIYLMTEESGGFGSGAVQMKAASAGAVPVAPKELANVKINLNPDAGKDSNVQADNSTDFVGKDEKAKPAEQAAPKCIVVPIVLKMADVDHETLLEEWIACRASEMGSSTPTQEEKEALLRKLQTIEDYLTSFEAQGMTVVNLSATAFPQTLDWLHSYLLECIEHGCSTSPSPGAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW90</accession>
    <name>A0A8T0HW90_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG319800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7712" checksum="AB1657E29BEF0801" modified="2022-10-12" version="1">MRFNALNGSLDGSPHLKELLHSYKSEWIKDGSKYGRTMLAHLLCLTNRSLKARTRIWRQGPGCGRGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWZ8</accession>
    <name>A0A8T0HWZ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG334300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="161"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="33198" checksum="E0EABE9F456F7E09" modified="2022-10-12" version="1">MGVDVNWAEFAFTQTHTHERHCPLPRLLQEFECLMEPLAPLKKVIPIENFTDPVHSMTTMVELGPTLHSLPAHPASGIPSKRNEPSSSTPIEDTKTFFMYSILPLPSLGSMDNKEAFPSMEDAALSALKALKGPVHTIVDGEQMRLRTARHEAYGPVANISQHLEEEKELLKHVNMKLTENKDSFNRAVEEYEKSRSFLTIARGDPLSLLPSDGSDRVKENPNLFESLVVSCSKIVDIARKQVGVWEFKSQRQYMIVEKLALDLSTAEAKYGEVCLEIDSEVDKLRALLIFLNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX36</accession>
    <name>A0A8T0HX36_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Strictosidine synthase conserved region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G020900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the strictosidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX36"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.30:FF:000032">
        <property type="entry name" value="Protein STRICTOSIDINE SYNTHASE-LIKE 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018119">
        <property type="entry name" value="Strictosidine_synth_cons-reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426:SF106">
        <property type="entry name" value="PROTEIN STRICTOSIDINE SYNTHASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10426">
        <property type="entry name" value="STRICTOSIDINE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20067">
        <property type="entry name" value="SSL_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03088">
        <property type="entry name" value="Str_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035779446" description="Strictosidine synthase conserved region domain-containing protein" evidence="6">
        <location>
            <begin position="22"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="Strictosidine synthase conserved region" evidence="7">
        <location>
            <begin position="184"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0575654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="397" mass="43982" checksum="B407631A1D0853B7" modified="2022-10-12" version="1">MGRLLPAGVLVVALVAYFIASDPLELSCLSGITDFQAQYVAVPPYNPLGNITRDGESRLQGAEIVGQGDVFGPESIAFDGQGKGPYTGLSDGRVVRYDGPELGWTTFATTSKRRSALCDYNHTPAPKLDYEHICGRPLGLRFEKTTGELYIADAYFGILKVGPQGGLAEPVVTEVNGVPFKFCNDLDFDGDGNLYFTDSSTKYHRRQFFISRLELENTGRFLRYNPVRKETTVLIEGLRFPNGVAVSKDGTFVVVAETNMARLLRYWLKGPKANTWEVWMDLPGVPDNVRRNENGDFWVAFHSRRSFIEMNSGAVPWLRHLVAKLPIPPKQLFPLLAPKPHALVIRYSSEGQVLEVLEDQSGKVVKVVSEVEEHDGKLYLGTVLFPQMAVYTLSSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0V6</accession>
    <name>A0A8T0I0V6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G130000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0V6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34689:SF1">
        <property type="entry name" value="NUCLEIC ACID-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="353"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="124"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="209"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="229"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="436" mass="51801" checksum="093FDF3FDCF231AE" modified="2022-10-12" version="1">MAAADRESDERHQSRSLERDRGRRHRRHRSHSPSPPKQGRKHSRSPSVEEYRHKNLAGGAEKHARKGDRDGSRGQELSHRTTEGKLEREGVLEDRDVGSLKARKGSLEDDREDDRVGARKSSKSSKDDRKVERHSGVTSDEFSEDSDSEDSDTDRGRKRRSRAKSHKHRSEKKSKSKHRAVRSESEQDESQTEGTSGESSEDSEDEYRRAKRRKRLKQKEKDERERKEERRRKKEKKRKLKEKEREQEKKKKKKEKVEKRAKGPITESWGKYGIIKELDMWTRRPEFSAWLAEVKKVNLETLTNREEKDMFKQYMEDYNTATFPSKKYYNIDIYHRRKVTKQRLKGMKDAMAKQTERTEFNDEEQRRQELIAERAKQKETELDKIKRTMMETGMGKAMREQAVLREEMQYHYRIGNKEAAEKIQRRLEPDVPGALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I144</accession>
    <name>A0A8T0I144_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G095400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I144"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12083" checksum="E97C95A29C2572E8" modified="2022-10-12" version="1">MTLAMQRPRTWTTDRISPTKFAHPSVQLTSSPRTNRDIQLVGFGLVVPAMAISKPPLRGNLFNCERIQLLLRAITDPDYLITYIISIKTSFKLYPTTLCLDKLYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1G5</accession>
    <name>A0A8T0I1G5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G085600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1G5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020">
        <property type="entry name" value="FLAVIN REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15020:SF47">
        <property type="entry name" value="NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="210"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="NADH:ubiquinone oxidoreductase intermediate-associated protein 30" evidence="2">
        <location>
            <begin position="344"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="3">
        <location>
            <begin position="515"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="645" mass="69022" checksum="CBFDB12A5512B858" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2K4</accession>
    <name>A0A8T0I2K4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G135700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2K4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="535" mass="56990" checksum="57791639BDBAEC67" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3H5</accession>
    <name>A0A8T0I3H5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_5G160700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SF3A3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3H5"/>
    <dbReference type="OrthoDB" id="2160351at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051421">
        <property type="entry name" value="RNA_Proc_DNA_Dmg_Regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025086">
        <property type="entry name" value="SDE2/SF3A3_SAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031774">
        <property type="entry name" value="SF3A3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024598">
        <property type="entry name" value="SF3a60/Prp9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021966">
        <property type="entry name" value="SF3a60_bindingd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786:SF2">
        <property type="entry name" value="SPLICING FACTOR 3A SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12786">
        <property type="entry name" value="SPLICING FACTOR SF3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13297">
        <property type="entry name" value="SDE2_2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16837">
        <property type="entry name" value="SF3A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12108">
        <property type="entry name" value="SF3a60_bindingd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11931">
        <property type="entry name" value="SF3a60_Prp9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="11">
        <location>
            <begin position="415"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="328"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0577495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="510" mass="59605" checksum="8811DE4DE9ACBCE3" modified="2022-10-12" version="1">MSGTLLEQTRAFHEEIERLERCIVQELQGETKSHKERLHQNHRVNNMRHAILDATGKLVEIYEDKDHAREDEIAALGGQGVGQNYFTSFYERFKEVREYHRRHPNAREGVTADDPEEYLKEEPYIDFSGEEAYGRYLDLHELYNQFLNSKFGQPIEYSAFLEEFSQTHKISRGVKLTKQYQDYLKSLTNYLLSFFERTQPLQDIDKIFAKVDAEFEERWNAGTVQGWEDKGVGTDQASTRGQPLIDIEDYDNVEELLELGPDRLKEALAALGLKTGGTPQQRAERLLLTKGVALEDLDRKHFPKGYQTPIMKKSEKEIAQHVAASKAVALAEVKLQRLCELLQEAVEETKSHVEKKQALTYEEMEAEREEEEVAQESESEDDEQAIYNPLKLPMGWDGKPIPYWLYKLHGLGQEFKCEICGNYSYWGRRAFERHFKEWRHQHGMRCLGIPNTKNFHEITSIKDAKALWERIQERQGVNKWRPDLEEEYEDLDGNVYNKKTYSDLQRQGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3L6</accession>
    <name>A0A8T0I3L6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G173200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3L6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="50016" checksum="DA1196249C06BD46" modified="2022-10-12" version="1">MASRFSDSSLYCVAALVRWHLPARSLVRFKLVNKEWETWISQNLRELAKVRKQTPSDWYFPITAMSYGEGRAGAEVKPLAAIHHPSDEAHKLPDLDYLPNWRGGRSNPYSIKAVSGGLFLSYYNSSELSTSDFYVVNPLTRKWRKLSRGNCCHELGWDFLHAQMVVDENVGAYTVIVLTDNCLNVYSSHSKHWVCNPLRYSRGIHDPFLHDPFLPLCARSRFPASACVDGYVYVCSRILKERPRSVVEIQMFPIQPVAEQHPTRSPTIVALGNFRAYDIYLGRVYLNLASPLLVECMGGIYIVVCNCEIVETSQNTVPGVLAVGVLAVVMRRVIHIFKFQEGSKICPLHVHYVSERKLLIGSRIFSVVWNRRDKFSCTAKSSVIWVAWDNHLLQYDIVSSVWKDGDHFIDLFSSEDDKLLNQDYDLLPSAYTPSFDLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I427</accession>
    <name>A0A8T0I427_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G186200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I427"/>
    <dbReference type="OrthoDB" id="1897217at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38357">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38357:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="232"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="31581" checksum="AADEAF6028C7B614" modified="2022-10-12" version="1">MVALLGFASSVGGSARLVLDERVVQLGGVGDVNSLVCWPVRTSWKGFGVCAGRGAALDVRCRGSGGKGSSGYTYARDRVVDFGKNKGSMLGTLSSRYLGWMTKNLRGTMLEEWADYAQQTLDDPLYKDRIEWEKVEKLLMHSHDLAQLSNSRHALAPARMYGWDIDNDSAWSQVNFALLGTTKGGKIPRVPIVKEPKPKVQTKSEPEKKPASTRISKGSSKWASTPVVEGGSLRDELDRRRQARRDRLQAQRDALLAGSKDMQETNAKFPGRGGLLSKLQENNSQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I475</accession>
    <name>A0A8T0I475_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G190800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I475"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11966" checksum="0E6CA2E2FDDD40C8" modified="2022-10-12" version="1">MLTRHCSWFPNLQGKSQLHLGLRKEFNIYGALKTSECPLAFGTFRKNFQISRFLGSLSLLGAYGGARDERESFKKKKTPKSGFPAFNQAALFTSLAQRHTLQRWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4R1</accession>
    <name>A0A8T0I4R1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RAB6-interacting golgin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G033700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GORAB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4R1"/>
    <dbReference type="OrthoDB" id="1921288at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007033">
        <property type="entry name" value="GORAB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21470:SF2">
        <property type="entry name" value="RAB6-INTERACTING GOLGIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21470">
        <property type="entry name" value="RAB6-INTERACTING PROTEIN GORAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04949">
        <property type="entry name" value="Transcrip_act"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="145"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="24005" checksum="B14978F40A51EBF6" modified="2022-10-12" version="1">MAMMAEVSVGSLEQSLRETLHKEAEESERRQKAAEIQKLVWEERRSVISASLPPHLSGGTAPGEQAKQDSDSAVKIVHAKEQEIEKRKLQVREKVQAQLNRVNNEARSLDQLRKELEGLEDPTKQEVADIRKKIEVVDRELRPIKQLCEKKEKELKDALETYNEKSKIKTDLVGRLMDIVTESERQRMHKLEELNRLLEEMGRSKGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I900</accession>
    <name>A0A8T0I900_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small EDRK-rich factor-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G062100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SERF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I900"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040211">
        <property type="entry name" value="SERF1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13596:SF0">
        <property type="entry name" value="SI:CH211-39K3.2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13596">
        <property type="entry name" value="SMALL EDRK-RICH FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0578948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7296" checksum="41154341D40056A5" modified="2022-10-12" version="1">MTRGNQREKDRERAAARAKQTKERNDGLTPEQRRERDAKALQEKLAKKAEKGDGGSGSSSGSPGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID43</accession>
    <name>A0A8T0ID43_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G197300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="17115" checksum="B62D3827A02E89FA" modified="2022-10-12" version="1">MRVETARKLCELVDELGAILIRAPPGSAKTSLLQLVAQIITPTIFENVYYISLAEVSGKTFESLWAEWYPGINLTGIRSPPKCTGTNPERRPNLLLVDEGQAGIHMNLTLWGTLKSVMGGFKPHLRMIVVSAWGSELAATLKTAYTPGGFGRSSSVGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF42</accession>
    <name>A0A8T0IF42_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G256800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19094">
        <property type="entry name" value="AKR_Tas-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000005">
        <property type="entry name" value="NADP(H)-dependent aldo-keto reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="3">
        <location>
            <begin position="92"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0581496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="432" mass="47359" checksum="5C2F8F681AA8AA95" modified="2022-10-12" version="1">MACSAMGALAACGSELCLMPCSSSKLSWSRSSHVASSSGLVSVARVGNVDVGSARRGGGGCGVHVRASVASSPKTGTMQYRKLGDSDLVISEITLGTMTWGNQNTEKEAHEQLSYAFDNGINIFDSAEAYPIPMTAETQGRTDRYISTWLKTMPRDKVIVATKVAGYSEKSTYLRDSGKTLRVNEENITESVEKSLKRLGTDHIDLLQIHWPDRYVPLFGDKMFDPKKVRDSVPILDQLQALKNVVDQGKVRYVGVSNETSWGVMEFTRLANELNLPKIVSIQNSYSLLVRTQFEVDLVEVCLPQNCNVGLLAYSPLAGGSLTGKYILNPEASSSGRFNLFPGYMGRYNKSLAREAVSAYVEVAKKHNLSPVELALGFCRDRPYVTSSIIGATSLEQLKENMNAFAATRPLPEEVMADVEEVFKKYRDPAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFC0</accession>
    <name>A0A8T0IFC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G262400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyltransferase 77 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.-" evidence="2"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052636">
        <property type="term" value="F:arabinosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052325">
        <property type="term" value="P:cell wall pectin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053250">
        <property type="entry name" value="Glycosyltransferase_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005069">
        <property type="entry name" value="Nucl-diP-sugar_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46936:SF1">
        <property type="entry name" value="ARABINOSYLTRANSFERASE XEG113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03407">
        <property type="entry name" value="Nucleotid_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Nucleotide-diphospho-sugar transferase" evidence="4">
        <location>
            <begin position="164"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="54"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="72"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="647" mass="73359" checksum="040A66092B7E29F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIL9</accession>
    <name>A0A8T0IIL9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Agenet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G082000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd20405">
        <property type="entry name" value="Tudor_Agenet_AtDUF_rpt1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20403">
        <property type="entry name" value="Tudor_Agenet_FMRP-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014002">
        <property type="entry name" value="Agenet_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055274">
        <property type="entry name" value="SWO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429:SF1">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00743">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="1643"/>
            <end position="1720"/>
        </location>
    </feature>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="1737"/>
            <end position="1795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="418"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="669"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="825"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="901"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1807"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1880"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1941"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="903"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="939"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1004"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1082"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1197"/>
            <end position="1212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1261"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1550"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1585"/>
            <end position="1596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1624"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1836"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1846"/>
            <end position="1858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1880"/>
            <end position="1894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1895"/>
            <end position="1904"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1977" mass="212546" checksum="680E18635DAB55EC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJC2</accession>
    <name>A0A8T0IJC2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G074900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34213:SF2">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2 (NTF2) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="31508" checksum="94621DFED9B20F12" modified="2022-10-12" version="1">MADDAPKPQLEAPGDLDTDSGISYRDALKSSDTSTVVQDKEMQSNPPAVEEEEPAQASAAKETNTEPNPSTIEESEPAPTATEATTEPTPLNAVESDASSTSKETTTELGKIAKQIIPHILNLYNSCPSATDFDAIYAPNATFEDPLMQAHGVAQIKSAFYAMPKVFLDSSVLKYTVKEEQTAPKSGEICVDNLQQYKLLQLGPVGYFITMQSLIKLKVEGGKVVRHEDLWGGYRLWNRHTVRVPLVGRMAETVRRGSMLLTHVLMGFGKDHKTLDKPRDASVRLMVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK55</accession>
    <name>A0A8T0IK55_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Light-mediated development protein DET1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G088100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK55"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031461">
        <property type="term" value="C:cullin-RING ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031625">
        <property type="term" value="F:ubiquitin protein ligase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019138">
        <property type="entry name" value="De-etiolated_protein_1_Det1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13374:SF3">
        <property type="entry name" value="DET1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13374">
        <property type="entry name" value="DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09737">
        <property type="entry name" value="Det1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="452"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="524"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="811" mass="90971" checksum="7C981470EC0FA555" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKA2</accession>
    <name>A0A8T0IKA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Autophagy-related protein 18b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G193900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the WD repeat PROPPIN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKA2"/>
    <dbReference type="OrthoDB" id="1667587at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034045">
        <property type="term" value="C:phagophore assembly site membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048720">
        <property type="entry name" value="PROPPIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11227">
        <property type="entry name" value="WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21032">
        <property type="entry name" value="PROPPIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="392" mass="42300" checksum="47E2F748191B482A" modified="2022-10-12" version="1">MSLTVQPGFRRLLSLAFNQDNSCVAIGTKDGFKIFNCDNCRCYYQRSEGAINVVEMLFSTSLVAVVGAGQQPALSPRRLSVFNMTTDALQAELNFVSSILCVRMNRKRLVVVLERKTYIHELGQLAILHAIDTVSNTRGLCALSPNHENCYLALPASTTNGSVYVYDALDLHVLCQIQAHRSPLAAMSFSSDGLLLATASDQGTVIRVHSIPQASKEYTFRRGSYPATIYSLSFGPPSQVPQLLAASCASGTIHVFKLGNFARSRNEDLTSSVGQTSNGMAAGLLASVIPNSMSDMVESERCFLTIKNGSPPNIRSHCAIAAHLEDADEDGEEGPTSVSSSNRARIFVVTAGGFFHEWSITVGQGRESTCTLQREVALLSSSSSDEISAHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMA2</accession>
    <name>A0A8T0IMA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G174800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="24829" checksum="16E199BDA18BADAF" modified="2022-10-12" version="1">MKRKAQRRYLPQRPRRRPTATRPSRATIRKKPTKGRAHGGPSSRPPAAPKPTYFSLLKDVENYLKVDHVEGATMQKLKREMEKRYGGAAFDDASCKMLKSAVKRLQNKGRIKKNPNSTLLKYKPPVVPAYNVFGAGRSKGVRVVPLKPPVLRRPATRAPPHRKHHVMIRKPMAKAPPMRKHLMTRAPSIRKHASASAKRSTRSLPSYRPPIRKRRYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQH2</accession>
    <name>A0A8T0IQH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G000900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035929347" description="Secreted protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="143" mass="16818" checksum="3415D1294A2CBD3C" modified="2022-10-12" version="1">MKVSKHIHLLIVGISILVRVPYRGCVSNEFSTLSNISAVSLKPFVIHVSLATTTNRRWYALLTYHLLLYNFRRERQVWYNTDMECGTPCRRLYEFRCRRRGRKPTYRNAKSVTKGRSMTCKKPTTKHHFDKKGPKPTYHVLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQS6</accession>
    <name>A0A8T0IQS6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Staygreen protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G008300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the staygreen family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024438">
        <property type="entry name" value="Staygreen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750:SF4">
        <property type="entry name" value="LP06106P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31750">
        <property type="entry name" value="PROTEIN STAY-GREEN 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12638">
        <property type="entry name" value="Staygreen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Staygreen protein" evidence="6">
        <location>
            <begin position="154"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="372" mass="41669" checksum="04997EC76537BDC2" modified="2022-10-12" version="1">MATFSLCQPVAAMGSGGREGLVVGGREVSSVFSQPASAMVSLIACRKSEAERLCTEASRKVEGDALVSQFWSKGGREALAMKCAPVVMITHSAKLISGVVELQRPRLSLGGFELMSLMFEPSIFEVGKFLASFSRGIFRESSGLAAPLTLLAIEVAKLKVLFFGADKEHPDELPRIYTLTHSDVTSKITLAISKEINNAQLNGWFSKLQRDEVVAEWKRVQGKMSLHVHCHITGGNFLHNLIANLRFYIFRKELPVVLEAFIHGDEELLNTYPDLDNSMVWVYFHSNVKEYNRVECWGPLMEASKSASQEAMEAIHHAMEEMEKQWPKQLWPRKVCDEPCECCSHHETVIPLPKTFDLLQEEQKRQQEGSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRU6</accession>
    <name>A0A8T0IRU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G035300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12617" checksum="BE6CFE87DC9B7650" modified="2022-10-12" version="1">MKIPTPQPRKIPTCNPNPTTTIPCPPDQHRARKGLNRESTVARTIPGYELATTPLGGICAHRACQAAPSSAPSANMLRSWVRPSGVPEDVAPAVEGGNRSRIKVGEWSCDDCFASRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS75</accession>
    <name>A0A8T0IS75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G101300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000055">
        <property type="entry name" value="DnaJ subfamily C member 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188:SF2">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45188">
        <property type="entry name" value="DNAJ PROTEIN P58IPK HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="88"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="122"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="236"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="5">
        <location>
            <begin position="408"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="466"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0586580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="512" mass="57496" checksum="C335DA8319F4FDA3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISH6</accession>
    <name>A0A8T0ISH6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G055900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46539">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ATL42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46539:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE ATL42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="272"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="366"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="307"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0586005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="43778" checksum="06C59CFED2F7B15B" modified="2022-10-12" version="1">MMIKVAIAIGLGIFVFVAICCVSWGVWKLRHRMSKGQISATPDEIPIEDRKDVVLSLPTIKTSDLKVDGGAKLQCPLCWLDFRDEDIMRQLPQCDHIFHRHCIDRLLDKKITCPICSSVLTDSVKILENLNGRKSYLQETAMETIYSKEPARTPSWVHVNRPVPLPRTALLNSSSSSERFEIDLNPSDSMGSRDGKSPLLKHLTSSHAEEWNDVDLEKCIDISFTFGTDIPVEKRQHSRHSSTNDKDMDSFSFGISSEDAFTFVGTGGLESSSDAAAVGSSQRRSRNKDYSSSSSDFNPSTRHSRSTSRGSRSNSSGDSSFKQVANWDFGHPHLKEVSEHNASDHMPLTRPPDQCSYDVLPVVIGSGNHHLKPPQASEEHMKVGSHRNSYSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITA5</accession>
    <name>A0A8T0ITA5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G087200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11398" checksum="E852701DE6C52CCD" modified="2022-10-12" version="1">MDNFLKRLASPCIRPRVRSSSPRATGAKLSCRTPSPTKRKLLIISKSFSDCNRIPPGVTSSRHLVLILEIVLVLVRWRLGRSLLRVGRRSSSMPRLFGGSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUE7</accession>
    <name>A0A8T0IUE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Angio-associated migratory cell protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G090300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000074">
        <property type="entry name" value="Angio-associated migratory cell protein-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051179">
        <property type="entry name" value="WD_repeat_multifunction"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857:SF8">
        <property type="entry name" value="ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19857">
        <property type="entry name" value="MITOCHONDRIAL DIVISION PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="103"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="146"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="188"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="230"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="317"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="358"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="400"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="26"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0586436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="433" mass="45293" checksum="BBC6ADFF35A5EC3A" modified="2022-10-12" version="1">MTVPASRPPQENEEEDEGPIYVNDADVLEEFDVDEEDLPDVYDGDGDGDGDGDGDGNGDGSDGDGDGGDGGHGGADGSGGNQDFDMDDGDAVFPEQDDSVHAFSGHKGPVYSVACSPTDKGLVATGGGDDVTFIWRVGDAESHKQLQGHTDSIAALGFSHDGQLLASGGLDGIVNVWDSSTGALKQKLEGPGEAIEWVKWHPRGHLVLAGSEDVTAWLWNADTAACMAVLSGHSGAVTCGDFTPDGKTICTGSEDGSFRVWNPKTGESNRVVQGHPFHTEGLTCLAISNDSSIAITGSTDHNACLVNIQTGKVHATLAEHSKSLECVGFSSGLQLAASGAMDGKLIVWDLQTLQSRLTCEHEDGVVKLLWSPASQLVFTGCLDGKVRAWDGRTGNCERVFEGHGDSILDLAISRDGNMIISGSDDNTARVFEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV58</accession>
    <name>A0A8T0IV58_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G136900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="13720" checksum="5AF72DE6C7F17535" modified="2022-10-12" version="1">MKTYIRTHDSYAVIGPNNKFIKNINSHPEWLGYVPKLSISNFCSLFLQKSPSALTPQAPVSHKVHKNTSNSSGPRTNIWPQYLAIRISHRSRDKLMLHRYPYGKQRAGGFSRLKRRQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVF8</accession>
    <name>A0A8T0IVF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G145100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="360" mass="40829" checksum="A04C02D66FA0C1E1" modified="2022-10-12" version="1">MAGPSLSSIHGVQQSNLPLDVMECVLSLLPLPVLCRMRTVCKEWNHIICSSSFHDSYEQTWKERGHGVCFLTKFNSLNPFHTKIDRSVRGTTCFLDLDERRWYLIKGSVDQGFDTRDMAMDDGLVAEICCPVPPKEGYNIGARIIWCIQMSDPILKMRWRLDPCPNENRLPYLVVVAADRGSRVFRIFVYDNSGFGKTRLWIYESSTNKWRCASQPPRKGYDSNYASSAVVFQQGLYAIFTETDSLERFLVLYDFEKDTWSMVLENLPAAQLVELVVSSGKLFMMFGRSASSTSSAMMLEMVEIQVSEKTSRIVFQIPASTLSHIFGAVLSHYNIFAITCLTLRLNSDSSCSSVVLFSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW98</accession>
    <name>A0A8T0IW98_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G168100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW98"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035748391" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6849" checksum="0495FFA8A50FD894" modified="2022-10-12" version="1">MYLCNSQLNIWAVGLNVSLTVLCRCSHNVWHHCVCNILPWTRVFWLFPVQEVFYPLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWQ6</accession>
    <name>A0A8T0IWQ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G220600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWQ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="37" mass="4102" checksum="ECECFAD07846520A" modified="2022-10-12" version="1">MAGAVELGSDLFESLSRVEVNFGFLVWLGQRSDRLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXW6</accession>
    <name>A0A8T0IXW6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G175200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXW6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="15673" checksum="E18A2F96B0277387" modified="2022-10-12" version="1">MCAETLGNGGNVGTIHPVCFGYGGGRFRHNSFVMRYVKARRMPARWLKLASNDTFQAYVSISELMLGARGRSHSDAPGRDGVGDPFPAFSESRTNQRKLIVSGGHRITLKAHGKKSSSGESVKRGVLVQSLSPCEVLAHDGLMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYN9</accession>
    <name>A0A8T0IYN9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G209000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11364" checksum="AE3DDD128F03BF3E" modified="2022-10-12" version="1">MNPEQTNLGSRTSQPETPRLPISTPINHNRSPNAYIPKKKKLNPPTTPPRDLTQTPKPPRIAAKGTHANSATSIPTPTPPQITHHHNPRQRSHHIPLHQKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZI4</accession>
    <name>A0A8T0IZI4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Short transient receptor potential channel 4-associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G220700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZI4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019902">
        <property type="term" value="F:phosphatase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022162">
        <property type="entry name" value="TRPC4AP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31743:SF1">
        <property type="entry name" value="SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31743">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12463">
        <property type="entry name" value="DUF3689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="817" mass="92188" checksum="992DF0D79B892BAA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J073</accession>
    <name>A0A8T0J073_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Carbonyl reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G210200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J073"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490">
        <property type="entry name" value="(+)-NEOMENTHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43490:SF99">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0588033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="288" mass="31751" checksum="05EDC42DBE5F8C61" modified="2022-10-12" version="1">MATTPSTKWWSKDTVVVITGSNQGIGYEIARQLAQNGLTVIVTARSEERGKAAVEALRKELGTEAQDLVAFHLLDVTSDESVAALAQWLRQTYGGVDILVNNAAISRAETEEKIVDTNYYGVKRVTKAILPLLRPSPAGARVINVTSDLGALKHLSNKYRDEWKDRDQITEDQVDHFIQQYLGELKEGTWKSGGWQENYASYAVTKVALNAYTSVLAREVGPETEKVYVNCFNPGFAITNLNDYLGLSTLHASTLQEAAMTGIWLALHPVGGPHGKYLDRKNLGIAEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0A6</accession>
    <name>A0A8T0J0A6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G241300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0A6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="352" mass="40575" checksum="0CC06A1A55295D9F" modified="2022-10-12" version="1">MSSLGCKLSLAMDIPELSVIWVETHRYGNSTLGPEFISQGPSPHFVTRFCLSAIMWAVFNLVFQRLHFRMLRLPPRPSAWEWMFQTCVLRRNPAVVLHNLVKRYGPVMHIRAWSQDLIILSSVAAVEEFYKLHDMEFGARPSSMGRPTLSNALSSLCFPPLATYWKHIHLVLDMTTSQPFEDMSSRGFEWALEAIHRHPEVVQHLCEELERNLELHKPVRESAIAKLPYLQAVVKELFRLHTPCAVSFPHLQSSDEYCRLLGFEVPPRTQVLVNMYSVQRDPVMWVNPDDFDPVRFVARPEVDLLGQQFHLLPFGAGRRQCPGTKLAIQHVQLGLARYYFQRLVDKTSEKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1B7</accession>
    <name>A0A8T0J1B7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RNA-dependent RNA polymerase</fullName>
            <ecNumber evidence="9">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G014100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 9">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the RdRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="9"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1B7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031380">
        <property type="term" value="C:nuclear RNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030422">
        <property type="term" value="P:siRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00590">
        <property type="entry name" value="RRM_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057590">
        <property type="entry name" value="PH_RDR1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007855">
        <property type="entry name" value="RDRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058752">
        <property type="entry name" value="RDRP_C_head"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057596">
        <property type="entry name" value="RDRP_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058751">
        <property type="entry name" value="RDRP_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058763">
        <property type="entry name" value="RRM_RDR1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23079:SF5">
        <property type="entry name" value="RNA-DEPENDENT RNA POLYMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24823">
        <property type="entry name" value="PH_RDR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05183">
        <property type="entry name" value="RdRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26253">
        <property type="entry name" value="RdRP_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26252">
        <property type="entry name" value="RdRP_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26250">
        <property type="entry name" value="RRM_RdRP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="6 9" id="KW-0943">RNA-mediated gene silencing</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1163" mass="132760" checksum="B3EB9B66B010A786" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1G1</accession>
    <name>A0A8T0J1G1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G269800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006502">
        <property type="entry name" value="PDDEXK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01615">
        <property type="entry name" value="A_thal_3542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579:SF1">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04720">
        <property type="entry name" value="PDDEXK_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="407" mass="44580" checksum="B89E911555F8BC52" modified="2022-10-12" version="1">MAPVVKRNGKMGLLSTQLRACGAMGSGGSEAVAGSEAGKSRSKRIGNGVDVENRFGRECVSSGSEHEVNSVCLGAMVDRFLEDGAGGGRSVMRSRCSCKSMCECDFDEYKASQLGGELSEILQDLVPGVSVTERVLVCEVEKAIAEVVAAEGGVTTCLRRQVMKHLRTSGYNAAICKSRWEHVGSFPGGDYEYIDVVFAGKSERIMVDIEFRAQFEIARPSSSYNAVVQVLPAVFVGKADRLFQIVNIMSDAVKQSLKKSGLDLPPWRKPEYMRAKWFSSYRRTTNDTVHKAHGEDMANNISRIAVRDQGWNARYTEEMEVDYLRVGERRAMKDLKNLIAKKPTEVVSAKAAAVPAVVNNSDWTPPALKPRVFQRRGQAGLASILREAGLTSSIRSLIKEQRMAIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1Z1</accession>
    <name>A0A8T0J1Z1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Mediator complex subunit 15 KIX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G057800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.246.20:FF:000003">
        <property type="entry name" value="Mediator of RNA polymerase II transcription subunit 15a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.20">
        <property type="entry name" value="Coactivator CBP, KIX domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036529">
        <property type="entry name" value="KIX_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036546">
        <property type="entry name" value="MED15_KIX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044661">
        <property type="entry name" value="MED15a/b/c-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137:SF4">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16987">
        <property type="entry name" value="KIX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mediator complex subunit 15 KIX" evidence="5">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="327"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="413"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="535"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="708"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="908"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="189"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="424"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="549"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="563"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="708"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="908"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="932"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="946"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="964"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="976"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0589934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1357" mass="150907" checksum="B94A10400C9A3F79" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J330</accession>
    <name>A0A8T0J330_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA biogenesis protein RRP5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Ribosomal RNA-processing protein 5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G027100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05693">
        <property type="entry name" value="S1_Rrp5_repeat_hs1_sc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05695">
        <property type="entry name" value="S1_Rrp5_repeat_hs3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000065">
        <property type="entry name" value="Programmed cell death 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000624">
        <property type="entry name" value="Programmed cell death 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000103">
        <property type="entry name" value="protein RRP5 homolog"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000155">
        <property type="entry name" value="rRNA biogenesis protein RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000159">
        <property type="entry name" value="rRNA biogenesis protein rrp5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000179">
        <property type="entry name" value="rRNA biogenesis protein RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057300">
        <property type="entry name" value="OB_Rrp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045209">
        <property type="entry name" value="Rrp5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057301">
        <property type="entry name" value="Rrp5_OB_4th"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057302">
        <property type="entry name" value="Rrp5_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048059">
        <property type="entry name" value="Rrp5_S1_rpt_hs1_sc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270">
        <property type="entry name" value="PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23270:SF10">
        <property type="entry name" value="PROTEIN RRP5 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24682">
        <property type="entry name" value="OB_RRP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24685">
        <property type="entry name" value="OB_RRP5_4th"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23459">
        <property type="entry name" value="S1_RRP5"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="252"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="342"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="428"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="519"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="608"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="695"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="789"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="898"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1090"/>
            <end position="1169"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1198"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1302"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1412"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="11">
        <location>
            <begin position="1504"/>
            <end position="1574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="153"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1064"/>
            <end position="1086"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1586"/>
            <end position="1750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="52"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1608"/>
            <end position="1636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1646"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1694"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="1705"/>
            <end position="1716"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1721"/>
            <end position="1730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1731"/>
            <end position="1749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00073619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00076674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0589529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2023" mass="222934" checksum="0E37DDDA825EEA32" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J416</accession>
    <name>A0A8T0J416_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G092100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J416"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050781">
        <property type="entry name" value="CWC22_splicing_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN CWF22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18034:SF4">
        <property type="entry name" value="NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02847">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00544">
        <property type="entry name" value="MA3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="656"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="182"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="109"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="201"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="303"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0590347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="866" mass="96725" checksum="5C50F2FA8983C866" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J592</accession>
    <name>A0A8T0J592_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G091200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J592"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="200" mass="21614" checksum="432AAFC32E18EC9F" modified="2022-10-12" version="1">MAAGCDAPPPISMRRASDFCFSTFGTTTVRTPLSTFAVMRSRSALSGRRNLRMKLPLLRSTRCQVSVFCTSSFCRCPLMLSVRPSSICTCTSSLRRPGRSALNTCSEGVSFQSTLVLATARASRANEVAGALSKSDTITSSGSGTASHTLFRRPPKNDESAIAADQMRNSIKCYCNCPINPDDHSTVDDQDVLSILRRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6T2</accession>
    <name>A0A8T0J6T2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_1G168000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6T2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000101">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000146">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase IOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF77">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 14" id="KW-0732">Signal</keyword>
    <keyword evidence="3 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035798727" description="Protein kinase domain-containing protein" evidence="14">
        <location>
            <begin position="34"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="310"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0591337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="620" mass="67856" checksum="AEF8B8129FF25F77" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9I3</accession>
    <name>A0A8T0J9I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G262100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9I3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043454">
        <property type="entry name" value="NPH3/RPT2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32370">
        <property type="entry name" value="OS12G0117600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="1">
        <location>
            <begin position="539"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="649" mass="73763" checksum="8F3CFC2738906426" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBH2</accession>
    <name>A0A8T0JBH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">V-ATPase proteolipid subunit C-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G316700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the V-ATPase proteolipid subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBH2"/>
    <dbReference type="OrthoDB" id="10264021at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18177">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18178">
        <property type="entry name" value="ATP-synt_Vo_c_ATP6F_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.610:FF:000002">
        <property type="entry name" value="V-type proton ATPase proteolipid subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="entry name" value="lithium bound rotor ring of v- atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000245">
        <property type="entry name" value="ATPase_proteolipid_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10263">
        <property type="entry name" value="V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00122">
        <property type="entry name" value="VACATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="F1F0 ATP synthase subunit C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="V-ATPase proteolipid subunit C-like" evidence="11">
        <location>
            <begin position="107"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0593260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="178" mass="18655" checksum="0740B33CFA908623" modified="2022-10-12" version="1">MGFVAWWYAWTHALLYMSPYIYSAIGIAISIGVSVLGASWGIYITGSSLLGAAIKAPRITSKNLISVIFCEAVAIYGVIVAIILQTKLEATKQPFHPDSMRAGYSLFASGIIVGFANLLCGLCVGIIGSSCALSDAQNSTLFVKILVIEIFGSALGLFGVIVGIIMSSQATWPAAVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBH7</accession>
    <name>A0A8T0JBH7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial succinate-fumarate transporter 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G221800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBH7"/>
    <dbReference type="OrthoDB" id="1924968at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005469">
        <property type="term" value="F:succinate:fumarate antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000082">
        <property type="entry name" value="Mitochondrial succinate-fumarate transporter 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049563">
        <property type="entry name" value="TXTP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788">
        <property type="entry name" value="SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45788:SF2">
        <property type="entry name" value="SUCCINATE_FUMARATE MITOCHONDRIAL TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="119"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="219"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0592061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35871" checksum="41D8C88737845F90" modified="2022-10-12" version="1">MRTNSNPNSAPATSRNGVAIPSYVMAVSGSLGGLVEACCLQPIDVIKTRLQLDPPAHREYRGIWHCGSTIVEREGVRALWKGLTPFATHLTLKYTLRMGSNALFQSALADAQTGKLSASGRLAAGFGAGVLEAVAIVTPFEVVKIRLQQQRQIGNELLKYKGPVHCASTIVREEGVRGLWAGVAPTIARNGTNQAVMFSAKNYCDKLLWKKHEGDGVTLLPWQSMVSGFLAGFAGPLATGPFDVVKTRLMAQTRAGLPPGGEVQYKGMAHAITRIYAEEGVFALWKGLLPRLMRIPPGQAIMWAVADQVTGLYVRRTPSSALNLKSQSSSVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBW1</accession>
    <name>A0A8T0JBW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G326900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBW1"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36395">
        <property type="entry name" value="RING-H2 ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36395:SF1">
        <property type="entry name" value="RING-H2 ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="39366" checksum="FBE4AA7CA5156C54" modified="2022-10-12" version="1">MQAWNKLPSRISPNKLESLTSFHQFRVSREVACGGSGQGKHGPSNAGRIHLNPSLKSRMSRDSAHMSEMATNCLMSGADNSAAAAAALSIPQAELCVANAECVTAAELGSAEGLAKWLDERIPAEKPCISSWGVDPRTKRVANLWTELVDGEISLEDSKPPKRTVHVASVKVRNEAGMFLIESHQEMDDGRVRPRNRPLSEKMRPGETVEHACRRGVFEELGPEMGDRDRVEMILETYQREEEERDSFSYPGLLTRYVLHTMVASVRGLPSSDFCTQEDEGKPCNASGTNGAASNGAATNGAATNGAATNGAATNGAATNGAARSGTSVAKASHNGHAHGSGCAVGVKKHYWRWVTDVQLDAIMKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6P0</accession>
    <name>A0A8T0G6P0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G096200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6P0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751755" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5937" checksum="F0B1A10D29D5BE28" modified="2022-10-12" version="1">MVHFNLMLNLVIFSVTSVISSQVQILPLQTSLSFLVLCQNGSRNLCFLYIFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7E1</accession>
    <name>A0A8T0G7E1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G124900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7E1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035843342" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10564" checksum="DC789074A5A51B16" modified="2022-10-12" version="1">MAYLYQHSLISFFLFFLFSPNILSVEYSICGVLEVETPRLELTSETNCAGSRLSKKQEARERAGFRGDGTKVECLQDVLLSSVLDSAYILQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7Z8</accession>
    <name>A0A8T0G7Z8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">prolycopene isomerase</fullName>
            <ecNumber evidence="8">5.2.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_12G102600</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,7',9,9'-tetra-cis-lycopene = all-trans-lycopene</text>
            <dbReference type="Rhea" id="RHEA:30971"/>
            <dbReference type="ChEBI" id="CHEBI:15948"/>
            <dbReference type="ChEBI" id="CHEBI:62466"/>
            <dbReference type="EC" id="5.2.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carotenoid biosynthesis; lycopene biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Plastid</location>
            <location evidence="5">Chloroplast membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.13" evidence="8"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7Z8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046608">
        <property type="term" value="F:carotenoid isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014101">
        <property type="entry name" value="CrtISO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02730">
        <property type="entry name" value="carot_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313:SF3">
        <property type="entry name" value="PROLYCOPENE ISOMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0274">FAD</keyword>
    <keyword evidence="10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="18" id="KW-0413">Isomerase</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Amine oxidase" evidence="19">
        <location>
            <begin position="106"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0554587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="614" mass="66821" checksum="A687E4ED173919E5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G812</accession>
    <name>A0A8T0G812_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G008700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G812"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27815" checksum="7AAF15AB957FE901" modified="2022-10-12" version="1">MAMRRRTDIKVMEVETRGTPLVNALPGRGHRINPIASALADLKENEMAVRRIYSSQEKTPDHSVLQDRKIVNLLVTHNRDAVQRAIAEASTEFAKQTKALFESVFDAQDVATVFDAEDVATVKELTRSRRIKSLVDMFLKSKDGKATLRDMNKVTGRLDVHHDIKSCIKKEDVEELNQIRLKLDTLRSVPGGGFVDLISGYMEANMLMNTKLSAEDLALIQEKLDGGDTLGLGESSKSWLSHVTASLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8Z0</accession>
    <name>A0A8T0G8Z0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA 3'-5' helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_12G177100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001391">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001456">
        <property type="entry name" value="ATP-dependent DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF69">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q-LIKE SIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="9">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="538"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="894"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="210"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="340"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="826"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1105"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1251"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="260"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="1256"/>
            <end position="1276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00034808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0555551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1296" mass="143157" checksum="6D328C4AD7B7769D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEW5</accession>
    <name>A0A8T0GEW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Telomere repeat-binding protein 1-6-like ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G072000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057625">
        <property type="entry name" value="TPR1-6-like_ubiquitin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031105">
        <property type="entry name" value="TRP_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21717:SF70">
        <property type="entry name" value="TELOMERE REPEAT-BINDING PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21717">
        <property type="entry name" value="TELOMERIC REPEAT BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23603">
        <property type="entry name" value="Ubiquitin_TPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Telomere repeat-binding protein 1-6-like ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="22790" checksum="F1C7D2D6FCD4705E" modified="2022-10-12" version="1" fragment="single">MDAAMNLLGGGLRVQVLMQGKKVPNEAATVSQIGISRTGKLKSLGFMLEPSPVLTSASTTAEDPWLVLSRAANQPAPRYPVYGVHGLSGVGDGGVRCPMKGRSNKSSGVVVDPDPSMDILLIPFYNVALANLQETTFMKIAEQFDVADRRYYHLKPEYWREFDPSFAYYYLNELEDAEDRAVKLGKLEHYWQLEHLTIDYWSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGH3</accession>
    <name>A0A8T0GGH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_11G085900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Spindle pole</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000922">
        <property type="term" value="C:spindle pole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19509">
        <property type="entry name" value="RecA-like_VPS4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000159">
        <property type="entry name" value="Katanin p60 ATPase-containing subunit A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF78">
        <property type="entry name" value="KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0493">Microtubule</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="8">
        <location>
            <begin position="165"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0556878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="412" mass="45795" checksum="9295A084C27B54BF" modified="2022-10-12" version="1">MSEDLAAKSRWRFEDFEHAYDTKFGRLNGASKNHLSDYGCGTSMGSLFEMARPESNRYGFADKSSRAREKAPYEKYIQGAAALASSSGDFGAKPGARKNWQKPLPEFGSPEMLELAQNITREIVDGDLDVQWDSIKGLESAKRLLKEAVVMPIKYPQYFTGLLAPWKGILLFGPPGTGKTMLAKAVATECKTTFFNISASSIVSKWRGDSEKLVKVLFQLARHFAPSTIFLDEIDALVSTRGEGASEHEASRRLKTELLVQLDGLSTTSNELVFVLAATNLPWQLDGAMLRRLEKRILVPLPEPEAREAMFRTLLGEREGDELPWAAMVDSTKGFSGSDVRIVCKEAAMRPLRRILADLDMQRADSDCPLPQLDPITPEDVMVALKSTRPTVHLQAARYAEFNNDLGSQILW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLB0</accession>
    <name>A0A8T0GLB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G070500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030660">
        <property type="term" value="C:Golgi-associated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF22">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="32829" checksum="80C966207A6C1D23" modified="2022-10-12" version="1">MFYLFSSVSMIIMAFTLVSSVLSLGFTLAPYVTALNARLGDVVVISRSWFGPITRSQAALALFCVGVVTSWMVTGHWFLNNVLGISLCIAFVSHVRLPNIKVCALLLACLFVYDIFWVFFSEQLFGSNVMVTVATRQTSNPVHTVANSLNMQRISEVVVKKFDLPLKLIFPRTFWDVSSGNFRSQYLMIGLRDMAIPGMLLSLVLCFDHRKFREHDNEGTFSRGNKYIQFDGCGYALAMIAALAAGLLSQAAQPALLYLVPSTLGSILCAAWARGELAEPWSGPRPIVTEKSSFLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMS5</accession>
    <name>A0A8T0GMS5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G017900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="24077" checksum="1EE1F22C412D4999" modified="2022-10-12" version="1">MAPRSNRRAGMEGASSTDAMDVKGEVVAASRISVKVKDDSGAIKKIVVKTANGESITYVVENPGPRSPPPRMPVCRGQKCRREFRSDDEFYCAHCGLHRPEFSDRIFECRDKMCTKCGEKRGRGRQEFARFVEKVLKDHAGDLPAGEFTLEEDHVKQKVQTIIKGNYDNFKQEMERVGMHLIDQEAIFDYVRSRKNISARKRKKEQHLEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP13</accession>
    <name>A0A8T0GP13_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G172200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035799089" evidence="1">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10195" checksum="CC0E260A787179F0" modified="2022-10-12" version="1">MLVLFLTSFAAQGSSTSISSYKSDHFAFSTSISSYKTDNFAFIRRTSFTSYKNDHFAFSTSISSYKTDHFRFRCCWRQVSCEQLGSDYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR63</accession>
    <name>A0A8T0GR63_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G067400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-12 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000033">
        <property type="entry name" value="Kinesin-like protein KIN-12E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044986">
        <property type="entry name" value="KIF15/KIN-12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
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        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIN-12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37739:SF8">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KIN-12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
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        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57997">
        <property type="entry name" value="Tropomyosin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 7" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="10">
        <location>
            <begin position="273"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="683"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="880"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1029"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1168"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1354"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1533"/>
            <end position="1609"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1697"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1844"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="1935"/>
            <end position="1969"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2043"/>
            <end position="2098"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2176"/>
            <end position="2232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2344"/>
            <end position="2378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2428"/>
            <end position="2472"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2508"/>
            <end position="2650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="2690"/>
            <end position="2770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="354"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2816" mass="315320" checksum="3BDE880A7CAA2D71" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS68</accession>
    <name>A0A8T0GS68_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G030700</name>
        <name evidence="3" type="ORF">KC19_9G030800</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12455" checksum="FBBB0DFDAA408F99" modified="2022-10-12" version="1">MNKSYRINHMQVNSTNCFFHQLLARPRKPFLAMVFALGMTMCSRAWIFSAWRIWGIKTTTSTTRIKTTTSTTIGKAWKLKKFSMLLLLRHASNSLSVKSPSIKTHHHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSW5</accession>
    <name>A0A8T0GSW5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G111100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16464">
        <property type="entry name" value="RING-H2_Pirh2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039512">
        <property type="entry name" value="RCHY1_zinc-ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008913">
        <property type="entry name" value="Znf_CHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037274">
        <property type="entry name" value="Znf_CHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017921">
        <property type="entry name" value="Znf_CTCHY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037275">
        <property type="entry name" value="Znf_CTCHY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21319:SF53">
        <property type="entry name" value="RING FINGER AND CHY ZINC FINGER DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05495">
        <property type="entry name" value="zf-CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14599">
        <property type="entry name" value="zinc_ribbon_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161219">
        <property type="entry name" value="CHY zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161245">
        <property type="entry name" value="Zinc hairpin stack"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51266">
        <property type="entry name" value="ZF_CHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51270">
        <property type="entry name" value="ZF_CTCHY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035840560" evidence="6">
        <location>
            <begin position="28"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="CHY-type" evidence="8">
        <location>
            <begin position="73"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CTCHY-type" evidence="9">
        <location>
            <begin position="151"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="7">
        <location>
            <begin position="216"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="321"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0562023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="42141" checksum="4F9D5C41CF4E9CC4" modified="2022-10-12" version="1">MLGTARLRYWAGLVLKVLAVWFAKVLLQKQPIMSTFVDDEIDVIDGVESEDEVDFVEEMRLPEEKKVDDRLSVGSRTYGCKHYRRRCRIRAPCCKEIFDCRHCHNEAKNTNEVDDSKRHDIPRHRVEKVICSLCDHEQDVKQVCENCGVCMGEYFCTKCKFFDDETEKEQYHCDACGICRIGGRDNFFHCDRCGSCYSNALQNGHPCVENAMHQNCPVCVEYLFDSVMDISVLPCGHTMHQICLEEMNMHSQFCCPICSKSTQNMSRVWERLDQEVYLTPMPEEYRQKKVWILCNDCGTTSDVYYHVIGHKCLRCGSYNTRSTCPPSQSRRAEPRPSMGMLPEAIESSVSPNPAQPGRTLAAEMSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTR9</accession>
    <name>A0A8T0GTR9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G004700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTR9"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="309"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0563101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="61924" checksum="F8D02A879EC51CE9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYV0</accession>
    <name>A0A8T0GYV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">60S ribosomal protein L13a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G027700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYV0"/>
    <dbReference type="OrthoDB" id="1882297at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="6.10.250.3250:FF:000001">
        <property type="entry name" value="60S ribosomal protein L13a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1180.10:FF:000003">
        <property type="entry name" value="60S ribosomal protein L13a-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_uL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_uL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_uL13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_uL13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_uL13_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="Ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0563399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="208" mass="23848" checksum="799CBA5737486890" modified="2022-10-12" version="1">MVSGSGLCAKVVVVDARHHMLGRLASILAKELLNGQKVVVVRCEEICLSGGLVRQKMKYLRFLRKRMNTKPSKGPIHFRAPARILWRTIRGMIPHKTKRGAAALERLKAFEGVPAPYDKMKRMVIPDALKVLRLQPGHKFCLLGRLSEEVGWHHYDTIKELEEKRKAKSKVFYERKKQLIQLRIKATKRVEEQLSSLQETLAPITYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H076</accession>
    <name>A0A8T0H076_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G117400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H076"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.80:FF:000003">
        <property type="entry name" value="WRKY transcription factor 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044810">
        <property type="entry name" value="WRKY_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221:SF334">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR 57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="7">
        <location>
            <begin position="324"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="191"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="581"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="221"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="248"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="277"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0564523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="616" mass="67216" checksum="1F0F665F408E8490" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1F6</accession>
    <name>A0A8T0H1F6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G091000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1F6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="28"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0564194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1025" mass="114633" checksum="931DEB3623B4DB16" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1Z9</accession>
    <name>A0A8T0H1Z9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G107700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10762" checksum="4132ED612DA3A6F6" modified="2022-10-12" version="1">MATDERLRSQRGGQWLMRSSQYQCSRRVEKSSFEVLLNPLARNLLKWGILADLGRRRAKNGGGAAQTGHPEPNYQAVVPKVQAYRGFCRYHRTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2L0</accession>
    <name>A0A8T0H2L0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G200800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11671" checksum="35587A432442AE95" modified="2022-10-12" version="1">MAADRPRPPRGSRTQRATSVSPSWWLQGSKSSIKDSHTRTTGTSTLPGSRVKTEFGKRRGRGRGRGRGRSRCTALREGMVARSCLFAIQSWTSVSECPGRELNPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H311</accession>
    <name>A0A8T0H311_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G009300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H311"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9619" checksum="65BF7E9C87994E17" modified="2022-10-12" version="1">MPTPLRAAPNLLQDAPPSGRSSTQEIQARRSSINRTTSSKLHAQRRNLQLCSKWSKCHHLPIASRRHPHMGSLRMPPNAPIKALLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4S6</accession>
    <name>A0A8T0H4S6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G187500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4S6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12395" checksum="9845700D5339033C" modified="2022-10-12" version="1">MSHFPKTLTPSKCPQPIKTVQQSQYSQSTLSKYFTRHNAHSQLPNTRSKTEHNQNLCKQNLQPKGYRINTSHPPTTKQHLIIHLTLTLQSNTENPKMHNIAQHRCML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4W7</accession>
    <name>A0A8T0H4W7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G087600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4W7"/>
    <dbReference type="OrthoDB" id="2017169at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037494">
        <property type="entry name" value="RAF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040858">
        <property type="entry name" value="Raf1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040781">
        <property type="entry name" value="Raf1_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041358">
        <property type="entry name" value="Raf1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35299">
        <property type="entry name" value="RUBISCO ACCUMULATION FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35299:SF3">
        <property type="entry name" value="RUBISCO ACCUMULATION FACTOR 1.2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18579">
        <property type="entry name" value="Raf1_HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18578">
        <property type="entry name" value="Raf1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18087">
        <property type="entry name" value="RuBisCo_chap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubisco accumulation factor 1 helix turn helix" evidence="4">
        <location>
            <begin position="87"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco accumulation factor 1 alpha-helical" evidence="3">
        <location>
            <begin position="157"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco accumulation factor 1 C-terminal" evidence="2">
        <location>
            <begin position="284"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="48146" checksum="992AD34908A26738" modified="2022-10-12" version="1">MNMNTMKAPGAGLGACRLGTSLGVSGRRELALSGRGVSGKEARGLVCRAIGGGKNGPKVQITYEKNLYQPFRPPVSIETPAGATTAADQLEVLRERRGLWHEYAVLIPILSRTGYTPSMIDEETGMTGVEQNIIVVGSQVRNSLKASGFDEEMLQYFDLGGGELLYELRILSAMQRKASAEFIIERKMSPKEASELARSVKDFAMRKNSEGFKEFSSAPGDCLAFAFYRQSRECQEEEEVEAALQKALDVCVTDKARAKIQETLEKFASPDVSVESEPEETVFLQVIRLLEGEVVGTKLPTMLPVADATLESVEAVPSRASQGEGLFNVFSPAGWPSWVAIPGWDTVVHAGAPVAVVFPDAAKLPLQSNKNGKEKLREPTLVIVDKSVTLADDDQSLYVAVQSDSQELSILSASKVLDNRILGRVVLALRPPFPPSEDPVDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5T3</accession>
    <name>A0A8T0H5T3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G077300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5T3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035905875" description="Secreted protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="6610" checksum="F3EC7E94E0146EAF" modified="2022-10-12" version="1">MLACFIGAAMAICWRKACMAADGTRAAGTHGDSKSPRSESVHGGSTSLGYNRRVLEHGSVRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H702</accession>
    <name>A0A8T0H702_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Morc S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G073000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MORC ATPase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H702"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031349">
        <property type="term" value="P:positive regulation of defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000075">
        <property type="entry name" value="MORC family CW-type zinc finger protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045261">
        <property type="entry name" value="MORC_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041006">
        <property type="entry name" value="Morc_S5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336:SF80">
        <property type="entry name" value="PROTEIN MICRORCHIDIA 7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336">
        <property type="entry name" value="ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17942">
        <property type="entry name" value="Morc6_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Morc S5" evidence="12">
        <location>
            <begin position="434"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0566565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="864" mass="97431" checksum="448766A48DDE557C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H713</accession>
    <name>A0A8T0H713_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G027100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H713"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBC core" evidence="1">
        <location>
            <begin position="15"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="687" mass="79177" checksum="6437CD828C1D9666" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7U1</accession>
    <name>A0A8T0H7U1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peptidase S54 rhomboid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G056100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7U1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1540.10:FF:000013">
        <property type="entry name" value="Rhomboid protease aarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066:SF5">
        <property type="entry name" value="RHOMBOID-LIKE PROTEIN 11, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43066">
        <property type="entry name" value="RHOMBOID-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="Rhomboid-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S54 rhomboid" evidence="7">
        <location>
            <begin position="183"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="37432" checksum="88B96D1492464E31" modified="2022-10-12" version="1">MARAVRVCNPGLSFSSTLYASRSTLLPAMATAGMLRCCCATTQPPPLPLPGTIAHAPRPWATPLRHGFHTKPLSLLGLQSPATSLLTGRISALNGRGLRSVYPCRSVTRAMTRDSDSEIQRAKSNERGSLSHLELESSGDTKRKASFNGIFTLLLINFVAFAADHWLQLPFMRSLYLYHDYPRWYQFVTSTFIHASWAHLSSNLFFLYIFGKLVEEEEGSFAVWLSYLFTGVGANLVSWLILPRTVVSVGASGAVFGLFAISVLVKLSFDWRKILEVLILGQFVVEKVMEAAQASTQLAGRTYMGAANINHIAHLSGALVGVALIWMLNGITHLADKSSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7V0</accession>
    <name>A0A8T0H7V0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G137400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035818604" evidence="1">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5865" checksum="1DD3C93E764A2B39" modified="2022-10-12" version="1">MWWFGTTTLFALLCTHRISAPKHQQHSIIYSIHTFSMTYFHSRYLESST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8S5</accession>
    <name>A0A8T0H8S5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G109700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8S5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09612">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.30">
        <property type="entry name" value="Jacalin-like lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001229">
        <property type="entry name" value="Jacalin-like_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033734">
        <property type="entry name" value="Jacalin-like_lectin_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036404">
        <property type="entry name" value="Jacalin-like_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01419">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00915">
        <property type="entry name" value="Jacalin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51101">
        <property type="entry name" value="Mannose-binding lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51752">
        <property type="entry name" value="JACALIN_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="377"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="Jacalin-type lectin" evidence="8">
        <location>
            <begin position="679"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="79"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="94"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="406"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0567097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="92131" checksum="7DBA674583A8B3AD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAS9</accession>
    <name>A0A8T0HAS9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G050100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="12898" checksum="D0F9CA578E53039A" modified="2022-10-12" version="1">MAAAMNVHLLSFPIMVEDDFVVQLPTITLGQVSCILSPQQVLADYACFANSSGGAVVCDNKLVGIHTEALYGEEDGKERAMRNNTDNGKGGNGKGGNGKGGIEKGGSRKGGWKNVKSIDLDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC67</accession>
    <name>A0A8T0HC67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UTP-monosaccharide-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.64</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G063000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a monosaccharide 1-phosphate + UTP + H(+) = a UDP-monosaccharide + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13205"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:140358"/>
            <dbReference type="ChEBI" id="CHEBI:140359"/>
            <dbReference type="EC" id="2.7.7.64"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the USP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.64" evidence="6"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC67"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051748">
        <property type="term" value="F:UTP-monosaccharide-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06424">
        <property type="entry name" value="UGGPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.10.30:FF:000001">
        <property type="entry name" value="UDP-sugar pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000091">
        <property type="entry name" value="UDP-sugar pyrophosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039741">
        <property type="entry name" value="UDP-sugar_pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002618">
        <property type="entry name" value="UDPGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952">
        <property type="entry name" value="UDP- GLUCOSE PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11952:SF9">
        <property type="entry name" value="UDP-SUGAR PYROPHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01704">
        <property type="entry name" value="UDPGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00038047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00039080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="611" mass="67403" checksum="F4B91D1B8EFE7949" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCP5</accession>
    <name>A0A8T0HCP5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GS catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G101300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCP5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamine synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.70:FF:000009">
        <property type="entry name" value="Glutamate-ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000046">
        <property type="entry name" value="Glutamate-ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.590.10:FF:000012">
        <property type="entry name" value="Glutamate-ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.590.10">
        <property type="entry name" value="Glutamine synthetase/guanido kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383:SF2">
        <property type="entry name" value="AMIDOHYDROLASE 2 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43383">
        <property type="entry name" value="NODULIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="Glutamine synthetase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51986">
        <property type="entry name" value="GS_BETA_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51987">
        <property type="entry name" value="GS_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GS beta-grasp" evidence="3">
        <location>
            <begin position="479"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="domain" description="GS catalytic" evidence="4">
        <location>
            <begin position="579"/>
            <end position="913"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="913" mass="100282" checksum="E37B0FB75B379582" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEV6</accession>
    <name>A0A8T0HEV6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_6G072000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The histidine box domains are involved in binding the catalytic metal ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the fatty acid desaturase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEV6"/>
    <dbReference type="OrthoDB" id="10260134at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042761">
        <property type="term" value="P:very long-chain fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="ACYL-COA DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351:SF31">
        <property type="entry name" value="DESATURASE 1, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00075">
        <property type="entry name" value="FACDDSATRASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid desaturase" evidence="15">
        <location>
            <begin position="149"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0569187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="389" mass="43992" checksum="01793A3E7456F38C" modified="2022-10-12" version="1">MATAGAMSATVAPCGLQGLSLRRAVRRAPVEYRPCGVVARRSAGVGLRREVLPRRELLGVAVKGLAGGNVGRVSCVLEEAAPEQLVEGTEYPPSRIWLSDVVVRKRRNYFKNRQWTGKDLTYAGFMALMHGLCLFAPATFSWNAFGLFVGLYVITGMLGITLSYHRNLSHKSFKVPKWLEYTFAYCGVQAIQGDPTEWVSAHRYHHAHCDTENDPHTPYEGFWHSHMGWLLDDSRTQERVGAKNNVGDMEKDPFYNFIAKTYPIHPIMMGAALYALGGFPYIVWGMAVRAVWVYHITWFVNSASHVWGSQSWNTGDLSRNNWWVALLAFGEGWHNNHHAFEYSARHGLEWWQLDPTWWVIRGLEAVGLATKVKLPRKDHMEKLAFKSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFH5</accession>
    <name>A0A8T0HFH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_6G133800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFH5"/>
    <dbReference type="OrthoDB" id="260519at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF129">
        <property type="entry name" value="CYTOCHROME B5 ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3 12" id="KW-0349">Heme</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="13">
        <location>
            <begin position="4"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0570030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15309" checksum="E13BD80894A6F4C5" modified="2022-10-12" version="1">MAEKKVFSLEEVSVHNHAKDCWLVIDGKVYDVTKFLDDHPGGDEVLLSATGKDATDDFEDVGHSTSARDMMEEYYVGEIDPSTIPSKPTYTPAKQAAYNPDKSSEFLIKILQFLVPLAILALAVAVRFLTKNEDVKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFQ0</accession>
    <name>A0A8T0HFQ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_6G051100</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF14">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="244"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="77"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="182"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="281"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0568909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="379" mass="41056" checksum="6E8DD0CA52AA2285" modified="2022-10-12" version="1">MAETPRCPSLVTKLAGYSYLGSKLAPIRPTFASPELNTPFAAAATLGALPRQTCFNARGRNMPSHVFVPAAKETTFSSFMTDFLMGGVSATVSKTAAAPIERVKLLIQNQDEMLRFGRLSHPYKGISECFKRTINEEGVVSLWRGNLTNVIRYFPTQALNFAFKDYFKSLFGYRKDRDGYWKWFAGNLASGAAAGASSSFFVYHLDYARTRLSSDGKAAKGGGRQFNGLLDVYKKTLATDGVAGLYRGFTISCLGIIVYRGLYFGLYDSLKPVLLTGSFEGNFLASFMLGWGVTNAASIASYPIDTVRRRMMMTSGEAVKYNGSLDAFKQIIAKEGAKSLFKGAGANILRGVAGAGVLSLYDQMQILLLGTKYSSGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGI0</accession>
    <name>A0A8T0HGI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diaminopimelate epimerase</fullName>
            <ecNumber evidence="3">5.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G113500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGI0"/>
    <dbReference type="OrthoDB" id="4768at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.10:FF:000009">
        <property type="entry name" value="Diaminopimelate epimerase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689:SF0">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="380" mass="40868" checksum="194C47A521577FB8" modified="2022-10-12" version="1">MALRNQVLLGNRAGASAFGGDCSLFLPGKPLGTRAQRLAVQRSVLLWGARANLDSSSTSATDLFTEAASGRAGGGGVKLEKVFDSFDGVKGKASKRTLEFVKYHGIGNDFIMVNNLNSSEPIITPAEAVRLCDRHTGIGGDGVIFVMRDNDNYQMRIYNSDGTEPEMCGNGIRCVAKYLAEIEKATAPKSYKVLTLAGYMILELREDGQVCVDMGPPYLEAAEIPTKLAARGEVVKAPLVVDGKTWQVTCVSMGNPHCITFGEEGGEGLNVDALPLEQIGPLFEHHEMFPARTNTEFVEVISRTHLKMRVWERGAGATQACGTGACALVVAAVKEGRAERNCTVDLPGGPLEIEWRESDNHIYMTGPAERVFQGSVVLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGR4</accession>
    <name>A0A8T0HGR4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G121100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16872">
        <property type="entry name" value="ARID_HMGB9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22009">
        <property type="entry name" value="HMG-box_AtHMGB9-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.30.10">
        <property type="entry name" value="High mobility group box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045303">
        <property type="entry name" value="ARID_HMGB9-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009071">
        <property type="entry name" value="HMG_box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46691">
        <property type="entry name" value="HIGH MOBILITY GROUP B PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00505">
        <property type="entry name" value="HMG_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00398">
        <property type="entry name" value="HMG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50118">
        <property type="entry name" value="HMG_BOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="4">
        <location>
            <begin position="242"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="HMG box" evidence="3">
        <location>
            <begin position="507"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="HMG box" evidence="1">
        <location>
            <begin position="507"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="767" mass="83540" checksum="FABF929C8E6B76BF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMQ1</accession>
    <name>A0A8T0HMQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG067800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805566" evidence="2">
        <location>
            <begin position="24"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="397" mass="43341" checksum="35AA7067AC842C40" modified="2022-10-12" version="1">MGRQYWIWVAAAVMLSSSVLTTAKFTLHVPHQLDAEWKNMNDIGKLLAQAVHLPLHSQKMLLKDIGNVYAKTGEGRCNIFGGSASCEPIPKDSDYSKVCANANEKVDCAFRMTALEHISKDPQTHFRKQLAVEGLTECHECYKNMHHFWCGQVVPSCGTFDKVIDEILPMLTAVAERKEKPSVALQQAVPRILQSASLGLPCKEMCDTITTTCGCGRAATFGEVMKSIQSGKHRDMYSTNMSLSTAKDIFQNVWNKPVCELFSGMHTPGFSGVCQVPESLNKCSWCEGKAARPDFVHEQIVSQMAQSISGLMQGGLEEILLATGGEKVQGGAGWSWTHGDTGSKKKSGGHSGVWAVLIVLLFVAAGAFVAAVKIQRNRQNPSQYVDLNSMGYTPPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNI6</accession>
    <name>A0A8T0HNI6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha-1,4 glucan phosphorylase</fullName>
            <ecNumber evidence="2">2.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG085200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000807">
        <property type="entry name" value="Alpha-glucan phosphorylase 2, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468:SF28">
        <property type="entry name" value="ALPHA-GLUCAN PHOSPHORYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11468">
        <property type="entry name" value="GLYCOGEN PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="265" mass="29656" checksum="BE614789D052538B" modified="2022-10-12" version="1">MEFLQGRALLNAVGNLELKDEYTEALHKLGHDLEAVAEQEPIAALGNGGLGRLASCFLDSLSTLNYPAWGYGLRYKYGLFQQTITTDGQKEQCEKWLEMGYPWEIPRNDISYPVKFFGKVVDSYNGIKEWVGGETVSAFAYDVPIPGFRTKNSISLRLWSTRALPEDFDLEAFNAGDYSKAGQAHANAERICYVLYPGDATDEGKLLLLRQQYTLCSASIQDIIARFKERSGSELKWDALPSKIAIQMNDTMTAHFSIPSITMQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP28</accession>
    <name>A0A8T0HP28_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG107800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="334" mass="36735" checksum="51203D8AAB9999A6" modified="2022-10-12" version="1">MLLNAVLPMRQKAPIPDTAVDEVGNSEVSDQNKGVNASIVGETERCPPVPSTLPDRTTSASEVTEVMCTQNPSILTQAESYDCNHRGPRMNPSLATVCKDEEIPVETNVVPASNTPDVNTGIASGSKVRTGLQAAFGLAANEFSLQHGKRLGDPGTCLDPPPLKKGKASLLKLKKVYPQLLPSERTSTAVKRATVDRPKQSGKRPSKFLDYVPPADNKPRAEMCEPLQKSKVVWILHPDHQNKTIGLRRCGLSWRSYKKKLVPGVENVSWKHGMQQVTIEHVYPKWSQSKVLYPDLQCHGINTIGDALKGDFAVDATILWHTRYLNYVEVSKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ12</accession>
    <name>A0A8T0HQ12_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG128400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005202">
        <property type="entry name" value="TF_GRAS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31636">
        <property type="entry name" value="OSJNBA0084A10.13 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03514">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50985">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="924" mass="101337" checksum="B8503E816FC13623" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQK1</accession>
    <name>A0A8T0HQK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG141100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="117"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="423"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="428"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="557" mass="61384" checksum="D7795226A81C6B14" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS28</accession>
    <name>A0A8T0HS28_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG193100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="13633" checksum="632C6D0BCAB8C091" modified="2022-10-12" version="1">MYLTSVVDLLTRPRSQHITSCSTCRIFRSWLSRHQPSLGPVHQTLTRSTASQEYTFCFQPQAFNHFLAPRNLATSHTSASPTVTNRLMSPHRCFTAHERTNSTKHHHSPTRQLTYFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT76</accession>
    <name>A0A8T0HT76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG238700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15886" checksum="06B93E265E04FECF" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPPTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSGARKCADSHSKPSSTRRHSLPESSIGDRCRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTF3</accession>
    <name>A0A8T0HTF3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG254100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035814690" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8597" checksum="4F511AF266C17835" modified="2022-10-12" version="1">MMRIVLLIWKLFLRILVRFSGWRVQSMLSPNSTPYCILISKLICHSFKLNGNTVGWSSLAYCVGIDVLADMFILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXQ5</accession>
    <name>A0A8T0HXQ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G003800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9912" checksum="7FF2A7AA05A0EA2E" modified="2022-10-12" version="1">MRGVPQPGVTRSRSRLRSPSALPHASYLHIDQPSVPVPVPSLAPCLPCALPRSHSFRCPSPSSSAEFSYEKTSASRKNLGTHKFFIQNLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY60</accession>
    <name>A0A8T0HY60_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G013800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9738" checksum="1DEE1F916523B7FE" modified="2022-10-12" version="1">MISHVVTLVSAHPCKLLHANALLINHQTSPEHTSKTQIIAHHRTIMGWVCIASFDKKALEIDNSKLKVLICLRKVHARVNNPMVNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY84</accession>
    <name>A0A8T0HY84_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G057500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY84"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="95" mass="11092" checksum="C9F05213E03DAB8C" modified="2022-10-12" version="1" fragment="single">INIKDFSFLTWHKESSFVKTSLAFPFPFCYCALAIQLHCLELSALGMPITSYRILCRDFEFCWLAYMRIGCPVLSRDQKQSHLAVSSSIYWLMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYA6</accession>
    <name>A0A8T0HYA6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_VG338500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYA6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="72"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0575348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13107" checksum="E536E1C0775970D3" modified="2022-10-12" version="1">MDRPPQIQYEQNWDATIDHTLGRFVYGSLSGAASALLFFRCPTTRWAAVAFGAGAGIGSALTDSSQLFRGAISASSPPVSSPTPAVVPEVQQSSHADAPEPKHVEAPKLERFEEPLIQEAQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYL0</accession>
    <name>A0A8T0HYL0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Molybdenum cofactor sulfurase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G004000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYL0"/>
    <dbReference type="OrthoDB" id="10264306at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF76">
        <property type="entry name" value="OS03G0765800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="419"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="726"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="421"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="743"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="824" mass="91465" checksum="ECC99CF13323BFDB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYR2</accession>
    <name>A0A8T0HYR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G069500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="14980" checksum="A96CEBBD92F42BDF" modified="2022-10-12" version="1">MSEKDEKATPPVIPTAPTAPVIPPPPPVVPTIPSPLTTPAKVLVRELKREPAALGERAGSVTWEQPTALQTRQYPLWYRYRAAFGSLIIVNVCIGTYMLFTVKPKPKGSKKGKALSVNRSAIFSRWLLESTGSRSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYV2</accession>
    <name>A0A8T0HYV2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G043700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15977" checksum="86F4552D12D2DBEB" modified="2022-10-12" version="1">MMLYETPIPGLINLSSTTLTQIRRALQIKNWSLKIQEHTIIQKSAQKNAFSLQSSAQQKQHLQEKDQQTEAKDRTLRCSPRTFSSRISNMPNSNPKATSHDHPLQQRNYTLFPQLQSPGSIAETKHHRMNRKPQFPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0M6</accession>
    <name>A0A8T0I0M6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G099600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0M6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="15863" checksum="C036CB7EF0C96558" modified="2022-10-12" version="1">MERAIVHPHQPHFFPLALIDTSTIVYNTHFEVYFNLSPQEKDEVPAPYSSHCSKITQHRGGARTCPTARQVPGHRGNIVSCRRCDAPNKSSPLYTALIQMSQFQMFALSSVFTILNLGHLEGGSHSHSRKPKMVEIVYCQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0P4</accession>
    <name>A0A8T0I0P4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G057100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0P4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12333" checksum="ECBB81C0DB8A6512" modified="2022-10-12" version="1" fragment="single">SHIFTAVGNLTICRSSFICVRPHESLLRMFLVLESCKVMEEAVPRLISRILHLSDLGHWRFAKVSCGIPDRSLVGHFEPSHSAFDSKSSFPTWLNLPTGCHDDREIAASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0Z9</accession>
    <name>A0A8T0I0Z9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G090600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0Z9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11707" checksum="1B82C8ACFB3254AB" modified="2022-10-12" version="1">MVTTLKKVVLPNYREEAAAVAKDGVNRNNDGDQDFAAAGPRKTIVTTLKAKEGWPNRQDKFCFLFSVDRLVLFLLDSFIMRFSRCDKITCKYRIQSKYFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1C5</accession>
    <name>A0A8T0I1C5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G082700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1C5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="7826" checksum="41FB5D1F32E0E127" modified="2022-10-12" version="1" fragment="single">LLVCPSCLCDPHRGSPSPRSLCMSNIAHKRSMMGVKDPPFYSIVENTEIVINSGTKLKLALATCLHSLEISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1U9</accession>
    <name>A0A8T0I1U9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_5G107200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RLP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1U9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000275">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000233">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase TDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000213">
        <property type="entry name" value="Tyrosine-sulfated glycopeptide receptor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053211">
        <property type="entry name" value="DNA_repair-toleration"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060">
        <property type="entry name" value="DNA DAMAGE-REPAIR/TOLERATION PROTEIN DRT100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48060:SF21">
        <property type="entry name" value="L DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035883025" description="Leucine-rich repeat-containing N-terminal plant-type domain-containing protein" evidence="14">
        <location>
            <begin position="21"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="900"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="15">
        <location>
            <begin position="98"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0576781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="933" mass="101698" checksum="37B3E881885BF664" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I512</accession>
    <name>A0A8T0I512_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ubiquitin carboxyl-terminal hydrolase</fullName>
            <ecNumber evidence="8">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G034600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the peptidase C12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="8"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I512"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09616">
        <property type="entry name" value="Peptidase_C12_UCH_L1_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.532.10">
        <property type="entry name" value="Peptidase C12, ubiquitin carboxyl-terminal hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001578">
        <property type="entry name" value="Peptidase_C12_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036959">
        <property type="entry name" value="Peptidase_C12_UCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10589:SF17">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01088">
        <property type="entry name" value="Peptidase_C12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00707">
        <property type="entry name" value="UBCTHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52048">
        <property type="entry name" value="UCH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="4 8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UCH catalytic" evidence="9">
        <location>
            <begin position="7"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="23559" checksum="A43852A3A3B6A370" modified="2022-10-12" version="1">MSPASKCWLPLEANPDVMNKFLHGLGFPANGGCHDVVGFNDELLAMVPSPVLAVFLLFPIPKQVSENIYFINQSQNVRNAGATIALLHAVGNTVSQLHLEEGSFLQRFMKTTSVMTPHERGHFLETDIELREAHTMAAYGGDTQLGTVCDLHYITFMCVDDGLYELDGRKTGPVYHGPSSQETLLKDSVRVVEQTFIAHDPDSMRFNVIVLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I765</accession>
    <name>A0A8T0I765_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_4G031400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I765"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000001">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 16 17" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4 17" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12 17" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 17" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="15 17" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="6 17" id="KW-0934">Plastid</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 17" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0578541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="28372" checksum="5FF6C29EEA813BD2" modified="2022-10-12" version="1">MAAATACASTALAGQSLLKPVSELSRKVGNVEARVTMRRTVNKSAGSDSIWYGADRPKFLGPFSENTPSYLNGEFAGDYGWDTAGLSSDPETFARNRELEVIHARWAMLGALGCLTPELLAKSGVKFGEAVWFKAGAQIFSDGGLDYLGNPSLVHAQSILAIWACQVILMGAVEGYRVAGGPLGDVTDPIYPGGSFDPLGLADDPDTFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLNDHLADPVANNAWAYATNFTPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8F3</accession>
    <name>A0A8T0I8F3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">cytochrome-b5 reductase</fullName>
            <ecNumber evidence="4">1.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_4G139000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.2" evidence="4"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8F3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090524">
        <property type="term" value="F:cytochrome-b5 reductase activity, acting on NADH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06183">
        <property type="entry name" value="cyt_b5_reduct_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000032">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000009">
        <property type="entry name" value="NADH-cytochrome b5 reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001834">
        <property type="entry name" value="CBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19370:SF171">
        <property type="entry name" value="NADH-CYTOCHROME B5 REDUCTASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00406">
        <property type="entry name" value="CYTB5RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="11">
        <location>
            <begin position="91"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601834-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0579970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="343" mass="36690" checksum="BA1A34AAF070F7D1" modified="2022-10-12" version="1">MAMAMAMRRAGRAGALMRGAEFWGNGATGSARCMASVARVEDERSSSSGRALGAFGALLGAGALYGSCQGMINSEPAAAEEAGPKSALNPKEFVKFKLAEVHDVNHNTKVYRFTFDSQEALGLNVASCLITKAEIGKKKDGSPNYVIRPYTPISPPDSKGYFDLLIKIYPEGKMTQHLAHLKPGDELDVKGPIPKLPYTPNMKKQIGMVAGGTGITPMLQVIDAIVSNPEDNTQVSLVFANTSPADILLKAKLDALSFAHPNFKVFYVVDKSSEEWKGGKGYLNKDMLVKGLPAPSDDTLILVCGPPGMMNIVSGDKAPDRSQGELVGILKDLGYTSEQVFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAM3</accession>
    <name>A0A8T0IAM3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G104500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAM3"/>
    <dbReference type="OrthoDB" id="1932537at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040229">
        <property type="entry name" value="At3g27390-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31133">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31133:SF12">
        <property type="entry name" value="MEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="238"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="619" mass="68606" checksum="0E62F06D75E7DA83" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAR1</accession>
    <name>A0A8T0IAR1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein YIP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G178000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Golgi apparatus membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the YIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAR1"/>
    <dbReference type="OrthoDB" id="10256463at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039765">
        <property type="entry name" value="Yip5/YIPF1/YIPF2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12822:SF2">
        <property type="entry name" value="PROTEIN YIPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="8">
        <location>
            <begin position="126"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="50"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="302" mass="33058" checksum="42052D3F24DBADCB" modified="2022-10-12" version="1">MAGAYASLASEATGTVPAAAGAGHVLRFQDSNLQTFPPPHDIRGKMTSSFRPPHDAVETFSQPGPGAQGGQGWQNGQGGLGGQGGPSGPSQTWQGYFNVLSYRPYFNVDTVDVIDRIKDSLMVNVDFIEKTSYNPDMYGPFWICSTLIFFTASLGNFAAYLSYKSKTAGGHWHYDISLMSSAALLFYGYICLVPLSLYFLLRYLGVVSGLIQLWCLYGYSLFIFIPASLLSVVPWEIVRWVVVGVASFVSAIFVGGNIRAQIKTSSERWLAIVLGTVALHLALGLVLKLYFFTYFYQEAIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAV6</accession>
    <name>A0A8T0IAV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G181700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035939630" evidence="1">
        <location>
            <begin position="27"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="172" mass="18918" checksum="EC0FCE4EA8A2FB9C" modified="2022-10-12" version="1">MEHVFMFARLSLCALLFFSPSYGANGAPILRPRVQAELPPCEDVPGGIQNWDCYDPPLTAFPPCDFKHQNPGIDCSTDTQKPWPSPASEEKALTDISPADFASTHYIQSTSTPSGSAHHFQGMLPSCKDNWGGIPGWDCFDPPTTLLPLCDFKHQRAGFDCWPRDDPPGARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB42</accession>
    <name>A0A8T0IB42_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic</fullName>
            <ecNumber evidence="4">1.8.7.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Ferredoxin-thioredoxin reductase subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_4G153200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>[thioredoxin]-disulfide + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+) = [thioredoxin]-dithiol + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:42336"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.7.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin thioredoxin reductase beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.7.2" evidence="4"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103012">
        <property type="term" value="F:ferredoxin-thioredoxin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.460.10:FF:000001">
        <property type="entry name" value="Ferredoxin-thioredoxin reductase, catalytic chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.460.10">
        <property type="entry name" value="Ferredoxin thioredoxin reductase catalytic beta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004209">
        <property type="entry name" value="FTR_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036644">
        <property type="entry name" value="FTR_bsu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35113">
        <property type="entry name" value="FERREDOXIN-THIOREDOXIN REDUCTASE CATALYTIC CHAIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35113:SF1">
        <property type="entry name" value="FERREDOXIN-THIOREDOXIN REDUCTASE CATALYTIC CHAIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02943">
        <property type="entry name" value="FeThRed_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57662">
        <property type="entry name" value="Ferredoxin thioredoxin reductase (FTR), catalytic beta chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00026011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00048150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0580169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="17015" checksum="60D6008874F4EDCF" modified="2022-10-12" version="1">MACLMAGAGITGVFSSAHLSSRAAFSSQASGFSGASTTGFVVPRGLGVRAAGEPSDKSLEVMRKFSEQYARKSDTFFCVDKGVTAVVIKGLAEHKDTLGAPLCPCRHYDDKVAEVQQGFWNCPCVPMRERKECHCMLFLTSDNDFAGNEQVLLKALRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICJ2</accession>
    <name>A0A8T0ICJ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G193200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.110:FF:000052">
        <property type="entry name" value="Chaperone protein DNAj, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45504">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45504:SF3">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035849081" description="J domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="34"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="18116" checksum="80633304E86C9934" modified="2022-10-12" version="1">MRFCSFVDALLVFLVVTETHQTVFNMLRLCLYQDHYKVLGVDYDATDDSIRTSYLRLALKWHPDKHNGSTAATLKFQEINEAYRVLSDPLMRHEYDMQGNYGLQDYNYTVSNNIAFLCSVCSLTKFEIPCVFYRIGGLVMLISSGWHEILNCLMFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICM5</accession>
    <name>A0A8T0ICM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G257200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICM5"/>
    <dbReference type="OrthoDB" id="551907at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000002">
        <property type="entry name" value="Myb family transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025756">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499:SF43">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR APL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31499">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14379">
        <property type="entry name" value="Myb_CC_LHEQLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="14"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="101"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="243"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="102"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="293" mass="31690" checksum="D1A417F5CB6210B3" modified="2022-10-12" version="1">MYQEVKYEAMALVPARSASSNQDRPSLYGASFSSDGGVSSADPKPRLRWTPELHERFVDAITQLGGADKATPKTVMRVMGVKGLTLYHLKSHLQKFRLGKQLNRDGSGHGHEVAKGGAPAVQGTSSAGSDGPSTPKPQPQNQEGFQISEAIRMQMEVQRRLQEQLEVQRQLQLRIEAQGKYLQTILEKAKEALGNHIGASPGLEAAHAELTELASKVNSEPMNMSFPPLALPELPTHSADTRMANLPRQQSRVSDSSSQKSYVTQVAANPEDSGGASASCENQESTGVLKYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICP1</accession>
    <name>A0A8T0ICP1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G190900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="63"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0580679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="197" mass="21930" checksum="603287EB761DF9EF" modified="2022-10-12" version="1">MFLGTSECCELVQESCGKRVREFSRGLLVFAMPEMNGQDSPSTCVRGCCRSDCLPLAIPKSDIEIVAEIARGAESVVYEARYGGKSVAAKKPRLSTTDDMDQFHTELQILSKLDHPNIATLIGVRAYPPDYYFLYDLYEHGNLGDALHVSEWRPSLQQVMTIATQLAMALQYLHKVGIVHRDVKPANILVGFFSLCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDT7</accession>
    <name>A0A8T0IDT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G018800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10896" checksum="DA37F433F8911626" modified="2022-10-12" version="1">MGSPQVVSEVLVRGSHWNYDFVLFGETANWSRQCGSDKSSALTRTRESATRRDSLEVLLPGLPSGVIRASCTALVLEPEFDIHEAHQPLNSWGNSALPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEC6</accession>
    <name>A0A8T0IEC6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G204300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEC6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874:SF4">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874">
        <property type="entry name" value="RING FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="18465" checksum="62BD007B0FD1526D" modified="2022-10-12" version="1">MKEVEDGLGADGYEVVNVEDIVESIAGYVARYTSSVPQARNLTPMQLQEVMTQAFSDAERKGWLQSLYSTGRFLYTAGSWGVATLPIDKNPVVGCWLILKLITWKVLCTCTVHFRCVWGSNQQHLGCKFCRWRFSYRNITMIPKLYLFILTCNHSGIIYSHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEH4</accession>
    <name>A0A8T0IEH4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G208300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEH4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045843">
        <property type="entry name" value="IND-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16223:SF125">
        <property type="entry name" value="OS08G0506700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16223">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH83-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="394"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="46"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0580893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="466" mass="50301" checksum="65A53079504EBFBB" modified="2022-10-12" version="1">MGTTVRDATSFSAMLESSDHGSSSLDSVMTSSTSSCTGTPGDSHQFFASQHNSPLQESSYLPSFAASRQQLATPTSSGAQMPEWPYARDETWVFEPSRRTPGTRTADLRSNIGVSESYLDPPEDGRRSLQRGSSAPSRLYEECLADFNFAEVDRPRSSDPYGDIDDDLLSWADSLAPIVERGPQQMETEIPASDESSSVHGCSEQFFVCQTGFERQISTISTSTQSFGQEVVEPRSLMHQESLGAYGAIPAIEENMEESTTSPSFNQIGSFMSQAESMIGTSEETYGGANSTMSSAYSAPDYQASYHLGNELQTGAASGNGLWNSPGASGMLEGNKLLCGIGEIGNNEPAGWLGSTSAAGLNVGGTVEQAPLLPDLDLVPQSSLPSNPRAHRGHATHPRSVAERVRRGKISERMKKLQDLVPNMERQNNTADMLDEVVGYVKQLKLQVKELSQTVVQLKEMSLHPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF57</accession>
    <name>A0A8T0IF57_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NTF2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G228400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF57"/>
    <dbReference type="OrthoDB" id="6507044at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00780">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.50:FF:000005">
        <property type="entry name" value="Nuclear transport factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045875">
        <property type="entry name" value="NTF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002075">
        <property type="entry name" value="NTF2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018222">
        <property type="entry name" value="Nuclear_transport_factor_2_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12612">
        <property type="entry name" value="NUCLEAR TRANSPORT FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02136">
        <property type="entry name" value="NTF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50177">
        <property type="entry name" value="NTF2_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NTF2" evidence="3">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU369002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0581148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13584" checksum="4C05F8EFA07B72EE" modified="2022-10-12" version="1">MDPDSLSKAFVEHYYSTFDTNRPALAGLYQDGSMLTFEGEKIQGAQQIGAKLNSLPFTQCKHNVSTVDCQPSGPAGGMVVFVSGNLQLQGEEHLLKFSQMFHLIPTPTGSFFVFNDIFRLNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG22</accession>
    <name>A0A8T0IG22_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G011800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YIF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005793">
        <property type="term" value="C:endoplasmic reticulum-Golgi intermediate compartment"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005578">
        <property type="entry name" value="Yif1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083">
        <property type="entry name" value="YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14083:SF0">
        <property type="entry name" value="YIP1D-INTERACTING FACTOR 1, ISOFORM C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03878">
        <property type="entry name" value="YIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0581816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12211" checksum="9F904231C2D0C8DE" modified="2022-10-12" version="1">MVRNQGCSRGCNLEYRKLQSDQTILLTMSFMYGAGSGILATYLGNSRDYVQSNVSRYFATHDIQYYFQVTDQYIKNKLKVVLCPFPSSHSKLSSSSCLTSCNLKLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGA7</accession>
    <name>A0A8T0IGA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G021600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8508" checksum="A0FCA9B5D5B55C81" modified="2022-10-12" version="1">MSVLDFYPTVPVPIPIRIQIRVRMQWGSFRRIWRAREMGSVTATLYRSGSLPRHRWSRSSRVAPRVSVVIKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGL7</accession>
    <name>A0A8T0IGL7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G027600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="305"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="417"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="589"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="788"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="105"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="353"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="958" mass="110717" checksum="4CE59CBE79084026" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II09</accession>
    <name>A0A8T0II09_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G133400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11205" checksum="6F5D40D501BE7341" modified="2022-10-12" version="1">MRQKLLHITSTTVDQLNNVVNFLRRFSELPIRSIFTEPQLPTPTSPTTPAYERTSIPTPTTSSSKSHTKILKKNSPPTKPSLGYSRIQRRLPALACITTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL29</accession>
    <name>A0A8T0IL29_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G159300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="13657" checksum="5CF292A7E4FD37FE" modified="2022-10-12" version="1">MAVSPHQKQQNHRNNNNNSSDGDGDGDGDGDWGLALPVAIHETLGVITFSFAWGPIHEHWEVGEDHLDLPLQDQPSQGPPLCLPCPRCPSPCPTCATKSGCPESLANSLHFSPHPQTRHCLQTQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL82</accession>
    <name>A0A8T0IL82_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Ubiquitin-like modifier-activating enzyme ATG7</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Autophagy-related protein 7</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G152700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATG7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019778">
        <property type="term" value="F:Atg12 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019779">
        <property type="term" value="F:Atg8 activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000422">
        <property type="term" value="P:autophagy of mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006995">
        <property type="term" value="P:cellular response to nitrogen starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034727">
        <property type="term" value="P:piecemeal microautophagy of the nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032446">
        <property type="term" value="P:protein modification by small protein conjugation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01486">
        <property type="entry name" value="Apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.70:FF:000001">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme atg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000243">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.100">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.70">
        <property type="entry name" value="Ubiquitin-like modifier-activating enzyme ATG7 N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006285">
        <property type="entry name" value="Atg7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032197">
        <property type="entry name" value="Atg7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042522">
        <property type="entry name" value="Atg7_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042523">
        <property type="entry name" value="Atg7_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01381">
        <property type="entry name" value="E1_like_apg7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="UBIQUITIN-ACTIVATING ENZYME E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953:SF3">
        <property type="entry name" value="UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16420">
        <property type="entry name" value="ATG7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="Activating enzymes of the ubiquitin-like proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0072">Autophagy</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Ubiquitin-like modifier-activating enzyme Atg7 N-terminal" evidence="9">
        <location>
            <begin position="24"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="THIF-type NAD/FAD binding fold" evidence="8">
        <location>
            <begin position="352"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606285-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="696" mass="75995" checksum="47ACAEF90899FB0D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM51</accession>
    <name>A0A8T0IM51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G169700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="45063" checksum="509FDE233D4B82E7" modified="2022-10-12" version="1">MAGELDAELWSGLPTELMELVLQRLPISSLCKFRAVCKHWSTLPTVTAEDPYFLCFPFNSISCELYSFISCKLYSFTRNQWEDLDLSFLAPLLAQHCPGETISGHVIRLDNSCSDGGLLCLKGAICDDLGYEQTRFLLVCNPLTRTTKFLPSLDPDTTEDLMYLVHFGRSADYLMHRDPESGAYKIFAVVVEFHVQLHFYMYDSNLGLWEQILTLKRDDVGKNLRSCSIVFNGVYYNCACGGGKRAYELSAYNMKEGRWVVAGVQIPELDSSITSVSFLVRNDCLLLLAKTRWNRTRVYRIHDDSELGWKLSRRDGAKEINLPKELDWHQAFAYRDFILFHKEVHRNYMVVDIADRKKAVKTRIVPFFGLFRTGSGPLWPIYTRATFSLQATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQB5</accession>
    <name>A0A8T0IQB5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G050200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035923782" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="6991" checksum="4D52B6FD4FD1693A" modified="2022-10-12" version="1">MLYHTILCFFILQTTLCCSCAVCIIVEAKLQLRVEMNLEKENMAMTIQPAKPGEFATVVDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQE7</accession>
    <name>A0A8T0IQE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G270800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035871339" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9232" checksum="030090B93BCC0E79" modified="2022-10-12" version="1">MHLYLGLLLQLCTQACAELSFSNTNTNTRVAHMHQKRCATPPSPAKMDEASSTSIQASSAPGLSAAHLDVANVYPAYGPPQCTGRSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR00</accession>
    <name>A0A8T0IR00_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Zinc finger CHCC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G235500</name>
        <name evidence="4" type="ORF">KC19_3G235600</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR00"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.260.40:FF:000001">
        <property type="entry name" value="NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.260.40">
        <property type="entry name" value="q5lls5 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019401">
        <property type="entry name" value="Znf_CHCC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13156">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10276">
        <property type="entry name" value="zf-CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zinc finger CHCC-type" evidence="2">
        <location>
            <begin position="87"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0584804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="13966" checksum="51B09EE26C2DDF91" modified="2022-10-12" version="1">MAGSLRSLARFANAVRHHAGPRAPLPPSSSSSHASRAQAGAAVALFSGAGALRFMSADHTAKWMQNTEKKSPMELIDEVPPIKVDARVVACEGGTDPALGHPIEYISLDGEGPHVCKYCGLRYFQGNAHGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITC6</accession>
    <name>A0A8T0ITC6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Beta-fructofuranosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G088700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITC6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18624">
        <property type="entry name" value="GH32_Fruct1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050551">
        <property type="entry name" value="Fructan_Metab_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31953">
        <property type="entry name" value="BETA-FRUCTOFURANOSIDASE, INSOLUBLE ISOENZYME CWINV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035813111" description="Beta-fructofuranosidase" evidence="5">
        <location>
            <begin position="31"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="6">
        <location>
            <begin position="70"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="7">
        <location>
            <begin position="398"/>
            <end position="606"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0586412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="615" mass="69596" checksum="B1C5C5DFB8A97E94" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUL6</accession>
    <name>A0A8T0IUL6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G117900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="ARSENITE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675:SF30">
        <property type="entry name" value="CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035855231" description="Amine oxidase domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="domain" description="Amine oxidase" evidence="2">
        <location>
            <begin position="10"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="857" mass="96358" checksum="E2FA07BABE31E37B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUR8</accession>
    <name>A0A8T0IUR8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Initiator tRNA phosphoribosyl transferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G124200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043399">
        <property type="term" value="F:tRNA adenosine(64)-2'-O-ribosylphosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019988">
        <property type="term" value="P:charged-tRNA amino acid modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007306">
        <property type="entry name" value="Rit1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033421">
        <property type="entry name" value="Rit1_DUSP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033449">
        <property type="entry name" value="Rit1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31811:SF0">
        <property type="entry name" value="TRNA A64-2'-O-RIBOSYLPHOSPHATE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04179">
        <property type="entry name" value="Init_tRNA_PT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17184">
        <property type="entry name" value="Rit1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF007747">
        <property type="entry name" value="Ribosyl_Ptfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rit1 N-terminal" evidence="2">
        <location>
            <begin position="11"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Rit1 DUSP-like" evidence="1">
        <location>
            <begin position="427"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="540" mass="60359" checksum="9274551FD92CD0AC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV37</accession>
    <name>A0A8T0IV37_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G133600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="66"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12196" checksum="7A206F22DF1E7A59" modified="2022-10-12" version="1">MDSGNGSEDGTPWGRGDGQGDDDNNRDWGLKDIPNDVEVLKRVWRNEKSAPEILAYEFLRGGARARADRQHGGEHPRGCGEPGRHDAVHLRDGREPPHVPAAGVSARPLHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYH5</accession>
    <name>A0A8T0IYH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Palmitoyl-protein thioesterase 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G267000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247:SF8">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11247">
        <property type="entry name" value="PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02089">
        <property type="entry name" value="Palm_thioest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035807342" description="Palmitoyl-protein thioesterase 1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="313" mass="34158" checksum="0A53B7D78F1B49E7" modified="2022-10-12" version="1">MAERKCHALLVVAVILVALVGGSVDASEGEKPLPFIILHGIGDECKNQGLYEFTQLLINMSGAVGFCIEIGNGASDSFFMRLDKQADLVCDQVKSIQGLKDGYNIVGLSQGNVVARAVIEFCDGGPPVHNFVSLGGPHAGTASIPGCTLMSLCKLANALIRLGVYSPFVQNHLAPSGYVKIPTDLDAYYKGSLFLPKLNNEIAIYRNETYKKRLESLNHLVLIMFQQDAILIPPQTAWFGYYADNDFGTVLPPEETDLYKEDWIGLRALDEGGRVTYIAFPGDHLSINDLEVRDFIIPYLKSSPTGEVRVLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1T5</accession>
    <name>A0A8T0J1T5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G029000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1T5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043539">
        <property type="term" value="F:protein serine/threonine kinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06610">
        <property type="entry name" value="STKc_OSR1_SPAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000099">
        <property type="entry name" value="Serine/threonine-protein kinase BLUS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000208">
        <property type="entry name" value="serine/threonine-protein kinase BLUS1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047173">
        <property type="entry name" value="STRAD_A/B-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48014:SF21">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE FRAY2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="133"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="537"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="655"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="554"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="570"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="599"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="655"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="705"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="893"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="911" mass="102248" checksum="54A8B88F9BAF4582" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1W2</accession>
    <name>A0A8T0J1W2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G004700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the QWRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1W2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005880">
        <property type="term" value="C:nuclear microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007573">
        <property type="entry name" value="QWRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31807">
        <property type="entry name" value="AUGMIN FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31807:SF37">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04484">
        <property type="entry name" value="QWRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="15457" checksum="5060928E68F4941A" modified="2022-10-12" version="1">MEALESAILRVPVTGGARADVQAVKEALNSAVDVLNAVEGSVQFPLPKTQSMEALLSQLAETAAQERALLEECGDLLSVAASLEHGSDAIDSGTGHAPDGKKSKKYEELFPVETKRFGYVIPQAKSREAALDERVKKKADRYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2Q9</accession>
    <name>A0A8T0J2Q9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G019500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2Q9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903:SF0">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20903">
        <property type="entry name" value="PREFOLDIN SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46579">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="86"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14596" checksum="28E22CAD7B72C8FA" modified="2022-10-12" version="1">MLQNLVSTQKNLVISWIDCLKNLRKFCSSIDFFLQHQSNCLLMLAAFTSGLVKCCCLHFQKRFVLEPKDELIKEQQTKAEESDTAIAALVSSKEYLERQMKDVESNFRELLQNSPDLARQVMSMSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2T5</accession>
    <name>A0A8T0J2T5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7780 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G020600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2T5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056682">
        <property type="entry name" value="DUF7780"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34960">
        <property type="entry name" value="EMB|CAB68146.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34960:SF1">
        <property type="entry name" value="EMB|CAB68146.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25002">
        <property type="entry name" value="DUF7780"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7780" evidence="3">
        <location>
            <begin position="122"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7780" evidence="3">
        <location>
            <begin position="466"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="393"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="594" mass="66900" checksum="2A7440C17DBFD919" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4F8</accession>
    <name>A0A8T0J4F8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G126700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4F8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098542">
        <property type="term" value="P:defense response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004864">
        <property type="entry name" value="LEA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044839">
        <property type="entry name" value="NDR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31234:SF2">
        <property type="entry name" value="OS05G0199100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03168">
        <property type="entry name" value="LEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Late embryogenesis abundant protein LEA-2 subgroup" evidence="7">
        <location>
            <begin position="166"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0590790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="292" mass="31564" checksum="FB95EA97675CB1DA" modified="2022-10-12" version="1">MVEMGLLDSFKQSKVMRYTKGDRVHPATISDSPSPSIRSSSTAVGTPSKLPPGKKEEAGPMGWHKAGGFPNPPLPPPVTYGRPRRKSSSCSLCYCFSFFFSFLVILLILAGLTVFIIYVVFQPKLPKATIQNVAITKFNLTNRSGGPLKTLADLKNPVLNANIAFTIQVENPNEKLGIHFRDVSVIVAYNGTEFAHSFVAPFFQGKKTTSEVVANLKASSAPLSESQGKELQIAINQHDIPLSARINVGAALQIGSWVIPPGHIHVACNLRASSPTAPQGAKLLSKSCKWLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4X8</accession>
    <name>A0A8T0J4X8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FO synthase</fullName>
            <ecNumber evidence="7">2.5.1.147</ecNumber>
            <ecNumber evidence="6">4.3.1.32</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_1G071700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) from 5-amino-6-(D-ribitylamino)uracil and L-tyrosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 5'-deoxyadenosine + L-methionine + NH4(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55204"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:59904"/>
            <dbReference type="ChEBI" id="CHEBI:85936"/>
            <dbReference type="EC" id="4.3.1.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + 5'-deoxyadenosine + L-methionine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:55200"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:77846"/>
            <dbReference type="ChEBI" id="CHEBI:85936"/>
            <dbReference type="EC" id="2.5.1.147"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme F0 biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the radical SAM superfamily. CofH family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the N-terminal section; belongs to the radical SAM superfamily. CofG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.147" evidence="7"/>
    <dbReference type="EC" id="4.3.1.32" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4X8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141093">
        <property type="term" value="F:5-amino-6-(D-ribitylamino)uracil--L-tyrosine 4-hydroxyphenyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044689">
        <property type="term" value="F:7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01611">
        <property type="entry name" value="FO_synth_sub1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01612">
        <property type="entry name" value="FO_synth_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019939">
        <property type="entry name" value="CofG_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045567">
        <property type="entry name" value="CofH/MnqC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019940">
        <property type="entry name" value="CofH_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034405">
        <property type="entry name" value="F420"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020050">
        <property type="entry name" value="FO_synthase_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00423">
        <property type="entry name" value="CofH family radical SAM protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03550">
        <property type="entry name" value="F420_cofG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03551">
        <property type="entry name" value="F420_cofH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004884">
        <property type="entry name" value="PRK06245.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005609">
        <property type="entry name" value="PRK07360.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006687">
        <property type="entry name" value="PRK09234.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076">
        <property type="entry name" value="FO SYNTHASE (COFH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43076:SF1">
        <property type="entry name" value="LIPOYL SYNTHASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19288">
        <property type="entry name" value="CofH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00294">
        <property type="entry name" value="7_8-didemethyl-8-hydroxy-5-dea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01388">
        <property type="entry name" value="7_8-didemethyl-8-hydroxy-5-dea"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00343">
        <property type="entry name" value="aminofutalosine_synthase_(mqnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01064">
        <property type="entry name" value="F420__menaquinone_cofactor_bio"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01389">
        <property type="entry name" value="menaquinone_synthsis_involved"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="120"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="18">
        <location>
            <begin position="571"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00048468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0590099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="900" mass="98432" checksum="E7C9F5030CB930F0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J705</accession>
    <name>A0A8T0J705_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G174500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033554">
        <property type="term" value="P:cellular response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009893">
        <property type="term" value="P:positive regulation of metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051246">
        <property type="term" value="P:regulation of protein metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23818">
        <property type="entry name" value="RWD_RNF25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14046">
        <property type="entry name" value="STKc_EIF2AK4_GCN2_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000539">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000050">
        <property type="entry name" value="eIF-2-alpha kinase GCN2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.800:FF:000012">
        <property type="entry name" value="Histidine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="entry name" value="Anticodon-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024435">
        <property type="entry name" value="HisRS-related_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476">
        <property type="entry name" value="HISTIDYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11476:SF10">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12745">
        <property type="entry name" value="HGTP_anticodon2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RWD" evidence="13">
        <location>
            <begin position="38"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="475"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="320"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="330"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0591417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1293" mass="144626" checksum="41E437214D2C3AFE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J773</accession>
    <name>A0A8T0J773_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G172400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J773"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035922285" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11548" checksum="4427FDF1FDB80ED9" modified="2022-10-12" version="1">MACLQSGLACSLIFCNLQRLQALKLCCIVPVRLSKCSPRTRIRILERIESQGNTVSAAIPGHSFKFLNCVLVFHISTNSNSFVQFSFTIPPYDSHSEQIPLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8G0</accession>
    <name>A0A8T0J8G0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G232500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8G0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035883596" evidence="1">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="48" mass="5653" checksum="BB80D3261F393F7F" modified="2022-10-12" version="1">MLFYLIVYVWVNGTFGQNHVIGVKENRLELDVISKQPNEHLILRIQDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8T7</accession>
    <name>A0A8T0J8T7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G243700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8T7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050466">
        <property type="entry name" value="Carboxylest/Gibb_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033140">
        <property type="entry name" value="Lipase_GDXG_put_SER_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024:SF24">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024">
        <property type="entry name" value="ARYLACETAMIDE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01174">
        <property type="entry name" value="LIPASE_GDXG_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="97"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="38043" checksum="B68C0C34413A10A5" modified="2022-10-12" version="1">MATLWQLRLLSEVVVRANWMTRRKDGTLNRWLSDSLEKKVPANAKPVQGVSTMDVIIDAEAGIWARLFIPTQEMEVTPLQTAADGTQSDFTKKLPVIFYYHGGGFAVLCPNHNMYDKFCRRLARTCGAVVISVHYRRSPEHKFPVAYDDSYKAFEWLQSEEATPHMPPNVDYSRVFLSGDSAGGNIAHHVALRAAGKDLGRVKLKGLIIIQGFFGGEERTPAELQLKNVPIVSVDTLDWHWKAYLPKDANRDHPACNIFGPNSQDLSQIPFPPVLNIIGKLDILQDWEQRYSEGMKKAGKEVQTLVYEDGIHTFGLLNQVKLAPQMLVDIVNFINAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9L8</accession>
    <name>A0A8T0J9L8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G214100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9L8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000126">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF4">
        <property type="entry name" value="OS09G0441700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="454"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0591956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="58576" checksum="2F248F903B31F173" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAP9</accession>
    <name>A0A8T0JAP9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G296100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="9">Interacts with the C-terminus of GC5, but not with GC3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Golgi apparatus membrane</location>
            <topology evidence="8">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAP9"/>
    <dbReference type="OrthoDB" id="1867430at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01861">
        <property type="entry name" value="Rab6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000229">
        <property type="entry name" value="Probable Ras-related protein Rab-6A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050227">
        <property type="entry name" value="Rab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47977">
        <property type="entry name" value="RAS-RELATED PROTEIN RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0636">Prenylation</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00062504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0592990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="210" mass="23529" checksum="718DA35A0C0DB0DE" modified="2022-10-12" version="1">MGSMTISPLSKYKLVFLGDQSVGKTSIITRFMYDKFDVNYQPTIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVIVYDVSNRQSFLNTARWVEEVRTERGKDVVIVLVGNKTDLVDKRQVSVEEGETKTRELGALMIETSAKAGFNIKGLFRKIAGSLPGMESVNQPKEGDYVDINLKSTTNNTQSERQTAGGCAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBW8</accession>
    <name>A0A8T0JBW8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G327800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010770">
        <property type="entry name" value="Ecd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060:SF0">
        <property type="entry name" value="PROTEIN ECDYSONELESS HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13060">
        <property type="entry name" value="SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07093">
        <property type="entry name" value="SGT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="538"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="579"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="696" mass="76676" checksum="215E83322FEECBB6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD28</accession>
    <name>A0A8T0JD28_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(+) kinase</fullName>
            <ecNumber evidence="2">2.7.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G290700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>NAD(+) + ATP = ADP + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="2"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD28"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000006">
        <property type="entry name" value="probable NAD kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10330:FF:000018">
        <property type="entry name" value="Probable NAD kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF0">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20143">
        <property type="entry name" value="NAD_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0592923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="592" mass="65905" checksum="C246EDA6B31B81DE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDA7</accession>
    <name>A0A8T0JDA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G323300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035918455" evidence="1">
        <location>
            <begin position="22"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5887" checksum="D5B56152785F41E6" modified="2022-10-12" version="1">MFSEQLLVLILCCYTNSGSQCSFFGSFYHSNEELSYSNVGSTKVFSELVSSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7B7</accession>
    <name>A0A8T0G7B7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G148800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7B7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="14219" checksum="54CEB0CFB3EEAC4B" modified="2022-10-12" version="1">MSSINFYRTKSFPPANVTDCFTDCSTNCPVTLNEIFDPIPNFHIARDGNREELPNQRVSLCLYSGVQDWKGLEKALAEDGMEVRAKDDIVYVSGYVTRNDYNYNKEIREKVARYRRVSKSFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAJ9</accession>
    <name>A0A8T0GAJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyanobacterial aminoacyl-tRNA synthetase CAAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G172300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAJ9"/>
    <dbReference type="OrthoDB" id="2014299at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025564">
        <property type="entry name" value="CAAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033344">
        <property type="entry name" value="CURT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33222:SF4">
        <property type="entry name" value="PROTEIN CURVATURE THYLAKOID 1A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14159">
        <property type="entry name" value="CAAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035915330" description="Cyanobacterial aminoacyl-tRNA synthetase CAAD domain-containing protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanobacterial aminoacyl-tRNA synthetase CAAD" evidence="4">
        <location>
            <begin position="85"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0555487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="18464" checksum="9D032B5CE4A73B05" modified="2022-10-12" version="1">MACVAALSSSVAAAAAATTVGSSATRTSAAASASLALRRSLIHGNKVVLSSRRAESMRLNPLPIRAVSDDSTSDSSAQIQEFVEDLKAKWDATENKTTVGVYAGGALIALWLSSTIVGAINSVPLLPKIMELIGLGYTGWFVYRYLLFKSSRKELVEDIEELKGKITGAAKEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBM7</accession>
    <name>A0A8T0GBM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G109900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01366">
        <property type="entry name" value="KISc_C_terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000174">
        <property type="entry name" value="Kinesin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47972:SF28">
        <property type="entry name" value="KINESIN-LIKE PROTEIN KLP-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4 5" id="KW-0505">Motor protein</keyword>
    <keyword evidence="1 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="160"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="542"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="791"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="575"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="607"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="618"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="791"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="823"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="245"/>
            <end position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="906" mass="100425" checksum="B1F6B265457268D5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCN8</accession>
    <name>A0A8T0GCN8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G039700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11577" checksum="3EC0F01DF6F6502A" modified="2022-10-12" version="1">MIIIHPFSNVVQRVESFSHILFVSLVLISWNLLVVRCFIHRFRLAISEDDRCGSPCQYGLRHPRTCGNIRSLKANFGMPAEVVTSLSNMIYSFSIVRICTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCT7</accession>
    <name>A0A8T0GCT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G081400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8445" checksum="4280A0DDA668B7CB" modified="2022-10-12" version="1">MGIRQVVVQGWSSTAQAWSFAVAEGKANGTELCVPQFSERESKRKGKLSSPSFFAQLFRFSSVSARLVVFLQFRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDN9</accession>
    <name>A0A8T0GDN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_11G105400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts in the modification of cell walls via demethylesterification of cell wall pectin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000013">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF57">
        <property type="entry name" value="PECTINESTERASE 53-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pectinesterase catalytic" evidence="9">
        <location>
            <begin position="110"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00057335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0557140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="400" mass="44553" checksum="2EA5580BC0EE7A37" modified="2022-10-12" version="1">MSPVKKMADLRGFNISPMQWLCVQLLFFVVGIKLMVQGSEAGARGSVDALETFHHGYDQKLEVSSARHPRGGWGVRRRFVQGGADIEESYSRTWRSVFRDGAEFGDNTVMVVSLDGTGDYRSVQSAVDQVPDGNTRRVTVYITSGVYEEKVIIPITKPFITLQGEGRNRTVITWNDTADAAGTLMSASVVVKADHFIARDISFKNSAGPPVPTRVNMQAAAFRISGDMAFLYGCNFFGYQDTLYDHEGRHYYYRCLIEGSEDFIFGVARSLFERCWLHSIAEDGRGALVAQGKYYPGSIMGTSGYSFVSCIITGTGRPWLGRAWGQYSTVVYSFCEMDADIIPEGWYDWGLPERARTAYVGQYRCTGRGANTTGRVPWARELTDGEAQPFLSIQFIDGPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GES5</accession>
    <name>A0A8T0GES5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G044700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GES5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035844858" evidence="1">
        <location>
            <begin position="18"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="7086" checksum="ED6CEA870E965F08" modified="2022-10-12" version="1">MLFFFVVIFNIVRLFLQVFVPSDDFPMIAKKHWELRNGKLQNLFQGLKQYELSYMKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GET0</accession>
    <name>A0A8T0GET0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G096800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Required for protein transport from the endoplasmic reticulum to the Golgi apparatus.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat SEC13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GET0"/>
    <dbReference type="OrthoDB" id="364224at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030127">
        <property type="term" value="C:COPII vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031080">
        <property type="term" value="C:nuclear pore outer ring"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090114">
        <property type="term" value="P:COPII-coated vesicle budding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000017">
        <property type="entry name" value="SEC13 homolog (S. cerevisiae)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037363">
        <property type="entry name" value="Sec13/Seh1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11024:SF2">
        <property type="entry name" value="PROTEIN SEC13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="9" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4 12" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="12">
        <location>
            <begin position="216"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00060100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0557027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="33733" checksum="73F5EC84A6B2295B" modified="2022-10-12" version="1">MGATGLVKEAGGEQLVESGHQDVVHDVAVDYYGKRLATCSSDRLIKVFAVGAGDVPTVALAALSGHEGPVWQVAWAHPKFGSVLASCSYDRRVIVWREGAENEWQQDQVFQEHESSVNSICWAPQEFGLCLACGSSDGTISVFTHKPDGSWEKAKIEQAHPVGVTSVSWAPASAPGSLVGADPGPVQKLVSGGCDNTVKVWKHINNSWKMDCFPPLSKHSDWVRDVAWAPNLGLVRSTIASASQDGTVVIWTQAKDGDQWQPLTLNDFKTPVWRVSWSLTGNILAVSDSNNKVTLWKEDVDGEWSQVTNVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFJ1</accession>
    <name>A0A8T0GFJ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G101000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFJ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="210"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="501" mass="56623" checksum="C3F796E5AB5A1F10" modified="2022-10-12" version="1">MATISPEVTRQEADTTVSKLCSNFATAMQVSSTEEKPGLYTKSANSRRRRRRAGKNKAPVSTPGPRDANSTSTSTTGNHSLLSESSVFHTALQDPPPPDQAPTVPPLDASSASASACATQYYSARIQSMIENRAKCSDDVEYEIASSKVHWSTVDRPAGRTSKRRNAAQEGGGSSEDESEGEEVIDERELDEDILKANREAIKEQRDRLFERCEKIAEGGEAKIYAGIRTDESVGKPDRHVVFKVFPRGYHLRDLVKLWPEAAFSSPYIRGTKIEHVMLLPNDGRIAMVMRRAWGDLRRLIDMKKQANGNRGPPFNTKGVFDKMKWIASEMRWLHEDDVVHRDLKASNVLLYGNGDDFSTRCGNLESMDTRVCIEIISDYECALGVMGTRFWRAPEVLLGMRDPKKRFSPTLFTKKSDVYSYGMLCYEIATGFLPFEREGFSGTRAEQDLVINGKRPSFPDDVDGRVKDLITRCWHQDEEKRPTFKEIVDETKFLWYIYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLN6</accession>
    <name>A0A8T0GLN6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G043400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLN6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14153" checksum="6D7F76CD8A89A529" modified="2022-10-12" version="1">MAKGRMTIALDKTSKTEKMSSFAFQRLVATKFNEEMATQLPDLTAHEFLDCGYGHDIGKYEHGRDRQLEPLDTGRRSLPLSPKKRLTKSSRTPSTTSLPSHKAGWDWSKAKIYGSIPKGIYGDTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMF8</accession>
    <name>A0A8T0GMF8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G065200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.40">
        <property type="entry name" value="Invertase/pectin methylesterase inhibitor family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035513">
        <property type="entry name" value="Invertase/methylesterase_inhib"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101148">
        <property type="entry name" value="Plant invertase/pectin methylesterase inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="23451" checksum="577625681F1BCB26" modified="2022-10-12" version="1">MVEMDKCYTLVCVVVFLGSIIHGFTVGVRNGNRIGSKVGVENITLASEGSLSDRSGVTRQSLRISETEANSTFGFIVLQTGPDPAITAAMDNCVKALKQSTEQVEAVAAAFESFDATAQGQAFDDFRAQMNAAVEISRSCFKDCFVELSFDDWEAVRQLQSVCARQLQSHIQVWVDAEELYSQYLDLEFNRAQITRSTSWWSTSSNSSDVSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMW5</accession>
    <name>A0A8T0GMW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Chitin-binding type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G169400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMW5"/>
    <dbReference type="OrthoDB" id="941679at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008061">
        <property type="term" value="F:chitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00035">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000010">
        <property type="entry name" value="glucan endo-1,3-beta-glucosidase, basic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.10">
        <property type="entry name" value="Endochitinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001002">
        <property type="entry name" value="Chitin-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018371">
        <property type="entry name" value="Chitin-binding_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036861">
        <property type="entry name" value="Endochitinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044965">
        <property type="entry name" value="Glyco_hydro_17_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32227">
        <property type="entry name" value="GLUCAN ENDO-1,3-BETA-GLUCOSIDASE BG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00187">
        <property type="entry name" value="Chitin_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00270">
        <property type="entry name" value="ChtBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57016">
        <property type="entry name" value="Plant lectins/antimicrobial peptides"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00026">
        <property type="entry name" value="CHIT_BIND_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50941">
        <property type="entry name" value="CHIT_BIND_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00587">
        <property type="entry name" value="GLYCOSYL_HYDROL_F17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0147">Chitin-binding</keyword>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035798106" description="Chitin-binding type-1 domain-containing protein" evidence="8">
        <location>
            <begin position="23"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Chitin-binding type-1" evidence="9">
        <location>
            <begin position="22"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="54"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0560293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="410" mass="43898" checksum="2176FBEBAE19AC09" modified="2022-10-12" version="1">MAMSKVLLVALLIAVCTTVASAQDCDENRRCGDSRCCSQYGYCGCTIDYCGSGCKSQCNSCGGGGAAPTIGVCYGVLGDNLPSHSQVVALLKSRGVSNVKIYDAAHDVLQAFANSGIDLSVAVPNQEVRTVADSQDAANGWVQDNIRRFVGATKIGSIAVGNEYLTDSRNDPSKLLPAMQNIQRALEGQGLGNIKVSTPHEFGVVDISFPPSAGTFKGNYINVMRGILEFLRQKNSVFMVNIYPFFAYRFNSGQINLDYALFNPNAPPISDSGRTYRNLFDAQVDSVIAAMNRLGYGNLPLMITESGWPSGGGGVGAGVSNAKTYNNNLVKHVLQNGTPMRPGDRIPTYIFALFNENKKGGDAIETNFGLFFPDQRPVYDINLSATVSRPHNASAMDIDQAALVEPLAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN59</accession>
    <name>A0A8T0GN59_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G177000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13732" checksum="43B79259CB36CF01" modified="2022-10-12" version="1" fragment="single">WPDYAKTTIILWRERLWEEDYGRDRVWTERETESRFSPTVRVCFLPFAYSQTHSQTLPLPSPSPSPWRLAPPPTTCMATPPHPRTSLLLQTHFPQPIPLWGLPHRQTDRQRERTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNV4</accession>
    <name>A0A8T0GNV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G049600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035834201" evidence="1">
        <location>
            <begin position="29"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="10777" checksum="14205CD804B13866" modified="2022-10-12" version="1">MASIGKSVVWTTSVLLIVLVMVASSVEATRTLDDDPADVRHDEDHTPQGLTTLKAAACAMLGLPCGSEVLQCRGGGLPCIEKFTVCCSGRCVFIPGAQFSFCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQR7</accession>
    <name>A0A8T0GQR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">30S ribosomal protein S9, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G149600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQR7"/>
    <dbReference type="OrthoDB" id="10254627at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000312">
        <property type="term" value="C:plastid small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000001">
        <property type="entry name" value="30S ribosomal protein S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_uS9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_uS9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001099">
        <property type="entry name" value="PRK00132.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF1">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US9M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00035437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0560038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="226" mass="23997" checksum="FEA3F4972EE2A2BC" modified="2022-10-12" version="1">MAAMAAAASQALGLASSFGALSVQESGKRVGSLSSSGSLALRCNAVKMGVVVGRRTVVASPVVRAAVAEAAELESPEMEERRTLEAWVKQQLPGGFAAARLIGTGRRKTAVARVVLVEGSGKIVINNRTAQDYLQGNPLWLQAVKYPLASLGYETKYDIIVRAEGGGLSAQAQAILLGVARALIVANQANRDPLKKQGLLTRDSRIVERKKYGLKKARKAPQYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRD5</accession>
    <name>A0A8T0GRD5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endosulphine</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G010500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the endosulfine family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRD5"/>
    <dbReference type="OrthoDB" id="1902088at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004864">
        <property type="term" value="F:protein phosphatase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006760">
        <property type="entry name" value="Endosulphine"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358">
        <property type="entry name" value="ENDOSULFINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10358:SF6">
        <property type="entry name" value="ENDOSULFINE, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04667">
        <property type="entry name" value="Endosulfine"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="64"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="90"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="122"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU363120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="132" mass="14211" checksum="D3F5FCD7D68B967D" modified="2022-10-12" version="1">MYAGKREVEEPMGDQAENKHVQAPIPSLAEEEAIMKKKYGGLMPKKPPLISKDHERAFFDSADWALGKGGAPPGQKPRSLMETLRPKLQPSPHQSMSSRRSSLAAADGEGEGHVDGEGEPMNGTTNGETSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRG1</accession>
    <name>A0A8T0GRG1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G022300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="14508" checksum="829544B153D74DD5" modified="2022-10-12" version="1">MGTKHEHFLRLQCNARDIKIMIRGKNMNIRVALDGEIAHGEVVLNNDDVGWPRRISHVGSRNDGEDASHTGMKPVVSDCVRNDGFSSSEAMAMAMGATVNLAARRQAMVRVQPRLLSSACATTSVKWRCGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW70</accession>
    <name>A0A8T0GW70_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G075000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45717:SF15">
        <property type="entry name" value="AGL218WP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45717">
        <property type="entry name" value="OS12G0527900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="497"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="532"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="705" mass="79965" checksum="4B421ED30213A0D0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWU6</accession>
    <name>A0A8T0GWU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G125900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27718" checksum="137041911AD62C06" modified="2022-10-12" version="1">MCSEIGRQRLYLSIELCPGDDHVAVAVIVRGNAQRRPHSRRCIHDVGCARLLIRMICVASILRVALVDYLRRRGLAVARDLNRFPAAGVVVEPSRRHRYHPLAVGVILAVACPRGSAVSTRREAVYRHGRCGCRGRDRWRAGESPIFVSSYAAWVVVRVALVGCDSPRGEVPVRLARSSLRWRRSFRADVSADTGIIVALATHASKLSFTLVVKGARLVTSFQSLCMNAWDDQQRSNEKQGKEGTATRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXI0</accession>
    <name>A0A8T0GXI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G148200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000065">
        <property type="entry name" value="Phospholipase A1-II 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403">
        <property type="entry name" value="PHOSPHOLIPASE A1-IBETA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403:SF7">
        <property type="entry name" value="PHOSPHOLIPASE A1-IGAMMA3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="10">
        <location>
            <begin position="159"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0562458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="55213" checksum="D64E3BA10C1375DE" modified="2022-10-12" version="1">MAAKTDDKPPTPPGVEGTHNRLEPPAAGAQIGKRWRELQGANDWKGLLNPLDEDLRAEIIRYGEFAEVTYDAFDFDKHSQYCGSCKYSKKNLFKEVELHNTGYIVTRYIYATANVEVPYILRKSEREDAWSSKSNWMGYVAVSTDPEEIKRLGRRDIMVVWRGTQTGLEWAANFADKLIPAVLMPHAAKPAHVPLTKVKVEAGFFSLYTSANPDSKFNQISAQDQLQMEMRGLVDKYKNEPEELSITICGHSLGSALATLSAYDFAESGFNKLSVGDKNLAVPITVFSFAGPRVGNSAFKKRIEEIGVKVLRMVNVNDKVPRVPGVLVNENVPSLENLLDNLPWTYSHVGVKLELNDKHSKHLNQEKSASWTTHNLEVYLHLVDGYGRYDKLPIRDLVLVNKRCGFLKDDKFVPEEWWQLKNKGLQYFPDQRRWYQPPRALEDVPVPPKQETIDKVNFLKSNGQMNVLTAGHEADDKTAPITDLPKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXM2</accession>
    <name>A0A8T0GXM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G117300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1860">
        <property type="entry name" value="Uncharacterised protein family Ycf54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019616">
        <property type="entry name" value="Ycf54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038409">
        <property type="entry name" value="Ycf54-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35319">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35319:SF2">
        <property type="entry name" value="YCF54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10674">
        <property type="entry name" value="Ycf54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00043978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="21964" checksum="09A4B792041C7EFC" modified="2022-10-12" version="1">MEMAMAAAATIPVVHAGPSASSRLQCGVRLQRIGFPGGGSSGGHLRGEGRSAESCRSRPMRGACRALKPNLDEIATPPPAFVADQPQVFYFAVANAQSLMLEGAPLESVLQDGIERAERAKRSRDVWLIMEPAFLNQHPGLKALNAQLSKPTAAILSTNADWMLSFVKKSLPQAVIGKFLSPSTAVPDPLKSNLNANSDVVGGGGVWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXV0</accession>
    <name>A0A8T0GXV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding PCMH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G184900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; L-ascorbate biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762:SF7">
        <property type="entry name" value="FAD-BINDING PCMH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035937070" description="FAD-binding PCMH-type domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="4">
        <location>
            <begin position="59"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="633" mass="70723" checksum="3E198277963F2504" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXX2</accession>
    <name>A0A8T0GXX2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G088800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RGP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXX2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052691">
        <property type="term" value="F:UDP-arabinopyranose mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033356">
        <property type="term" value="P:UDP-L-arabinose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037595">
        <property type="entry name" value="RGP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31682:SF44">
        <property type="entry name" value="UDP-ARABINOPYRANOSE MUTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31682">
        <property type="entry name" value="UDP-ARABINOSE MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03214">
        <property type="entry name" value="RGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13331" checksum="48E731E1E10BE86A" modified="2022-10-12" version="1" fragment="single">VEDFKLPEMVRDASDVQLEEVDVVVALKPDLGYLAAWRELLKGCHLIVVQGGDFTGAIHVPAGFDDVDVYTRCDMVRLLGPELARALTFTGYGSRGFGYLVALGLDTLEETGNLLSCVCPQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYC5</accession>
    <name>A0A8T0GYC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G131200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050327">
        <property type="entry name" value="Proton-linked_MCT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360:SF317">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11360">
        <property type="entry name" value="MONOCARBOXYLATE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="414"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="444"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="491"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="565" mass="62254" checksum="20A3F97AA57D0C48" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ50</accession>
    <name>A0A8T0GZ50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G086700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="12789" checksum="8C380A8A95315D9E" modified="2022-10-12" version="1" fragment="single">MTTSPSAVQALHTPHSTLHVLSLNSRSKPLQCRQPPLHPTTRRTPLNHHRHRSGRSEATNMNLPASATSQYSKPSINQNPCTDSHPTFSRQQVETPSTTKHETGADRLHGLMCRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H053</accession>
    <name>A0A8T0H053_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G193900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H053"/>
    <dbReference type="OrthoDB" id="435038at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46158">
        <property type="entry name" value="OS02G0165000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46158:SF1">
        <property type="entry name" value="RING_U-BOX SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="415"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="238"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="484"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="56942" checksum="677ACE107697A00A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2L7</accession>
    <name>A0A8T0H2L7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">tRNA:m(4)X modification enzyme TRM13</fullName>
            <ecNumber evidence="12">2.1.1.225</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G123200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>adenosine(4) in tRNA(His) + S-adenosyl-L-methionine = 2'-O-methyladenosine(4) in tRNA(His) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43196"/>
            <dbReference type="Rhea" id="RHEA-COMP:10401"/>
            <dbReference type="Rhea" id="RHEA-COMP:10402"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74477"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>cytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Gly)(GCC) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:43192"/>
            <dbReference type="Rhea" id="RHEA-COMP:10399"/>
            <dbReference type="Rhea" id="RHEA-COMP:10400"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32767"/>
            <dbReference type="Rhea" id="RHEA-COMP:10397"/>
            <dbReference type="Rhea" id="RHEA-COMP:10398"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.225"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the methyltransferase TRM13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.225" evidence="12"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2L7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106050">
        <property type="term" value="F:tRNA 2'-O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030488">
        <property type="term" value="P:tRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007871">
        <property type="entry name" value="Methyltransferase_TRM13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039044">
        <property type="entry name" value="Trm13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022776">
        <property type="entry name" value="TRM13/UPF0224_CHHC_Znf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021721">
        <property type="entry name" value="Znf_CCCH-type_TRM13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12998:SF0">
        <property type="entry name" value="TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05206">
        <property type="entry name" value="TRM13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11722">
        <property type="entry name" value="zf-TRM13_CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05253">
        <property type="entry name" value="zf-U11-48K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51800">
        <property type="entry name" value="ZF_CHHC_U11_48K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="8 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CHHC U11-48K-type" evidence="14">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="522"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="522"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0564589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="611" mass="66456" checksum="69809C7896093539" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3V9</accession>
    <name>A0A8T0H3V9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G057600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3V9"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="149"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0563772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="24364" checksum="9C900E27D574F17F" modified="2022-10-12" version="1">MVSLKLQKRLAASVLKCGERKVWLDPNEVNEISMANSRQNIRKLVKDGFVIRKPQKIHSRARARRALEAKRKGRHSGYGKRRGTREARLPTKVLWLRRMRVLRRLLRKYRDAKKIDKHMYHDMYMKVKGNVFKNKRVLMESIHKSKAEKAREKTLSDQFEARRAKNKATRERKIARREERHAQGVPETAPAQAVEAPVTAAPVKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4L0</accession>
    <name>A0A8T0H4L0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G178100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4L0"/>
    <dbReference type="OrthoDB" id="2019491at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.160.20:FF:000004">
        <property type="entry name" value="Peptide chain release factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1660:FF:000002">
        <property type="entry name" value="Peptide chain release factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050057">
        <property type="entry name" value="Prokaryotic/Mito_RF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001859">
        <property type="entry name" value="PRK00591.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43804:SF7">
        <property type="entry name" value="LD18447P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="Release factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0488">Methylation</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptide chain release factor" evidence="5">
        <location>
            <begin position="127"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="424" mass="47156" checksum="7348E039E580257C" modified="2022-10-12" version="1">MRRLKLPALRLVRSLCSSPAVGRAFQETSDDVCVGVLGHGRWLPSSVRRFSTGEGQLPFSQDMLTIVERGMRTIEHRHARLNQALSEPEAPPDEIVRLSKELSKLEDFMACIASLKMKRKEMEGLKALIDESAEDEEMRQAAAEELRSVSRLESEDLQRMLSLMLPKDEADSRGCILEVRAGTGGEEASLFALDIFRMYERFAQKKSWNFEVLSITQTDSKGCKEASASITGDGVYGKLKFESGVHRVQRVPVTEKSGRVHTSAASVAVLPQADEVDVQMRNEDLRIDTYRAGGAGGQHANTTSSAVRVTHLPTGIVIAIQDERSQHMNRAKALKLLRAKLFERERIQQAMARSSLRLEQIGSGDRSERIRTYNFPQGRVTDHRINITQHSIDQIIQGEGLDGFIDALTMKQEIAALASLKAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5L4</accession>
    <name>A0A8T0H5L4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G201700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5L4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22725" checksum="C754192B6F315FD7" modified="2022-10-12" version="1">MRRARPALLQRVPGAMSTALEELVLDEIDETEAPYFTLRIISKTNPARLEVPASFTATTGWPGAAQCSLLTSLRDPKEWPLQMGQLPPSSRAGNAVSDSAGWINFLRHMPVSVGDILVFEHVDDRCLVASVAYHRGRRPQNAPEEPQVVHLDVPEDPQVLAVNVQELPQVVNVNVIEDPQVVNVAQELNTATTKTEATRNQIDRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H685</accession>
    <name>A0A8T0H685_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G137900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase GT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H685"/>
    <dbReference type="OrthoDB" id="2015856at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11299">
        <property type="entry name" value="O-FucT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11350:FF:000011">
        <property type="entry name" value="O-fucosyltransferase 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024709">
        <property type="entry name" value="FucosylTrfase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31741:SF4">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31741">
        <property type="entry name" value="OS02G0726500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="9" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="184"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00030350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0567481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="637" mass="71736" checksum="10C9D1E6565E1CF3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H688</accession>
    <name>A0A8T0H688_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G047500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H688"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035763568" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="65" mass="7114" checksum="439FF416D29456F2" modified="2022-10-12" version="1">MHLRGSLALRFLTATGLHSSLATPRFFPCRKRTVFPLATLHLLSTSLETSSSGVAESETATRRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6I7</accession>
    <name>A0A8T0H6I7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G029800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11723" checksum="76639532B37CC390" modified="2022-10-12" version="1">MVVGRSLFPFSLVIVHERFVYIGRIPPAHQDCPNQGHELGQLTSWLVYLVAREPGTLLQPPFFRNKEAVTHRSQIEYNLTILLRNCCCMVLSCFSPSLTVMCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H868</accession>
    <name>A0A8T0H868_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G188700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H868"/>
    <dbReference type="OrthoDB" id="28397at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000307">
        <property type="term" value="C:cyclin-dependent protein kinase holoenzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07840">
        <property type="entry name" value="STKc_CDK9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000043">
        <property type="entry name" value="probable serine/threonine-protein kinase At1g54610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000021">
        <property type="entry name" value="probable serine/threonine-protein kinase At1g54610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF387">
        <property type="entry name" value="F8L10.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="134"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="425"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="528"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="745"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="10"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="26"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="73"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="437"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="583"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="625"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="682"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0568131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="794" mass="87351" checksum="BAB8F793EC1D9AC4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8D2</accession>
    <name>A0A8T0H8D2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G182700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8D2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11137" checksum="542572C2947DB2CC" modified="2022-10-12" version="1">MQTPSAAQNLKKSTFANKGQITKPRSNFRTSTLPTTPTPHATHSNSRNWTTNATTEPRNHDLVTIHDRHPKSRSTRQLKPEPSKKFPTPPKRNNANLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8U7</accession>
    <name>A0A8T0H8U7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative gamma-glutamylcyclotransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G165100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Putative gamma-glutamylcyclotransferase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gamma-glutamylcyclotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.10">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045038">
        <property type="entry name" value="AIG2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009288">
        <property type="entry name" value="AIG2-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036568">
        <property type="entry name" value="GGCT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31544:SF2">
        <property type="entry name" value="AIG2-LIKE PROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06094">
        <property type="entry name" value="GGACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110857">
        <property type="entry name" value="Gamma-glutamyl cyclotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Gamma-glutamylcyclotransferase AIG2-like" evidence="5">
        <location>
            <begin position="10"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0567833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="22988" checksum="AF31051D66D6FCF5" modified="2022-10-12" version="1">MAATVVRNAFVYGSLLAPEVLTVLLQRVPRSSPAVVHDYHRYSIKNRIYPAVLPKKGDKVFGKVLFDLSEQELHILDRFEDIEYTKLIVSPLTLRAHENDSKVVDSAPNNEAQEINGVDTLENGLTLPNDQTGNMLLGNNTIEISPGHSVELGLATEVPAYMYIWAKQGDPDLFGDWDYELWRANHLQTFLRTDSGFSGSRSNSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H916</accession>
    <name>A0A8T0H916_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Photosystem I reaction center subunit V, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">PSI-G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G127800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PsaG/PsaK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H916"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.40">
        <property type="entry name" value="Chlorophyll a-b binding protein like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017494">
        <property type="entry name" value="PSI_PsaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000549">
        <property type="entry name" value="PSI_PsaG/PsaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023618">
        <property type="entry name" value="PSI_PsaG/PsaK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016370">
        <property type="entry name" value="PSI_PsaG/PsaK_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03051">
        <property type="entry name" value="PS_I_psaG_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195:SF1">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34195">
        <property type="entry name" value="PHOTOSYSTEM I REACTION CENTER SUBUNIT V, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01241">
        <property type="entry name" value="PSI_PSAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002912">
        <property type="entry name" value="PSI_PsaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01026">
        <property type="entry name" value="PHOTOSYSTEM_I_PSAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0567345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="17475" checksum="B500C42317D4B9C5" modified="2022-10-12" version="1">MASCAATMTGMAASSLSLKRSRAVQASAAPQVSFSGLRRGTKVDSIAMSRSSSFASQTAIAKSAAKVTCDGANTSLIITLSTGALLAMGRFVFLPFQRDNVSRQGLPEQNGTTHYEAGDSRAQEAVSFLKTNDPAGFTLVDVLAWGALGHAIGFFILATASNGYNPQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9C0</accession>
    <name>A0A8T0H9C0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Zinc finger AN1 and C2H2 domain-containing stress-associated protein 16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G098800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in environmental stress response.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9C0"/>
    <dbReference type="OrthoDB" id="431929at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1110.10">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035896">
        <property type="entry name" value="AN1-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057357">
        <property type="entry name" value="Znf-C2H2_ZFAND2A/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000058">
        <property type="entry name" value="Znf_AN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677">
        <property type="entry name" value="ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14677:SF20">
        <property type="entry name" value="ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01428">
        <property type="entry name" value="zf-AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25403">
        <property type="entry name" value="zf-C2H2_ZFAND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00154">
        <property type="entry name" value="ZnF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118310">
        <property type="entry name" value="AN1-like Zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51039">
        <property type="entry name" value="ZF_AN1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="AN1-type" evidence="9">
        <location>
            <begin position="7"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="AN1-type" evidence="9">
        <location>
            <begin position="95"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="8">
        <location>
            <begin position="274"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="213"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="214"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="226"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0566944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="33459" checksum="184FBA7BC9492C13" modified="2022-10-12" version="1">MGTPAMPDLGQHCSRDDCHQLDFLPFTCNACHKVFCLEHRQYKSHNCPNANEQDVTVIVCPVCKKSIRTVPNEDENVTWERHVRTNCDPSNYEKATKKPRCPVRGCKEILVFSNKVFCNDCKRDVCVKHRFGPDHGCEEYRKTNSSNRTISHYGNLFMKSFKERTAPATTQSNGRAGKQTANGASSSQSGGIAGAFTGLYSSVEAGINKLGLMSSSSGTRSENSSGRQTPSQGSRGQVPKPEECPQCRARFANVEQLIKHVEAMHETPSGEMLDVCPKCDKKFRDPILLVNHVERFHGGSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9F2</accession>
    <name>A0A8T0H9F2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">60S ribosomal protein L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G063300</name>
        <name evidence="8" type="ORF">KC19_7G168200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9F2"/>
    <dbReference type="OrthoDB" id="1861699at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.250:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1550.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="entry name" value="Ribosomal protein L11/L12, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_uL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_uL11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_uL11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_uL11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_uL11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_uL11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_uL11_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661:SF2">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="Ribosomal L11/L12e N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="Ribosomal protein L11, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL11 N-terminal" evidence="6">
        <location>
            <begin position="13"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL11 C-terminal" evidence="5">
        <location>
            <begin position="75"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0558901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0567870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="165" mass="17542" checksum="792B72407E213A3B" modified="2022-10-12" version="1">MPPKLDPSQIVEVYVRVTGGEVGAASSLAPKIGPLGLSPKKVGEDIAKETARDWKGLRVTVKLTVQNRQAKVAVVPSAAALVIKALKEPERDRKKVKNIKHNGNISLDDVIEIAKIMAPRSMAKELAGTVKEILGTCVSVGCTVDGKDPKDLQTEIDDGEVEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9P6</accession>
    <name>A0A8T0H9P6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G132600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9P6"/>
    <dbReference type="OrthoDB" id="1888446at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098869">
        <property type="term" value="P:cellular oxidant detoxification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039282">
        <property type="entry name" value="LSU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34283">
        <property type="entry name" value="PROTEIN RESPONSE TO LOW SULFUR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34283:SF1">
        <property type="entry name" value="PROTEIN RESPONSE TO LOW SULFUR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="33136" checksum="C19C1B0BA75319CE" modified="2022-10-12" version="1">MFYGWEDFKGDFRRSERVEAGEALIGDAMESVADLRRQIEFMSRDARVKDASIAKLQRELESTSAALVSEQAKHAETMARNLELERELEERIMQERGLVKQLEDQGDKHDKEMAEVKAWYENEIQRLVDSLETLEDAEERLVAQLGDLEAEAMEQNRYFNAEIGSLSQSLARKEQELASSQTELESIRQRQISLKELEAMDLAAQLLKSTNECDKMRLRTESLQGEMERVKTKASNLQQELALAKLVSSWQQENKSIQEEKIRAPSQLCRSESLSLGTQRRARHTAVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA09</accession>
    <name>A0A8T0HA09_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G025500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="20962" checksum="E96139AB05948D81" modified="2022-10-12" version="1">MAARSLSAAMSNTFSNCQGHKRLRSNAIETIPNSNHWKLSNITTPLGFPTFRTNTLHKLSRKLSPKLSRQPRQSPARRLSENFYATPNILAMRQIRHRDHAQTLKSTEPPTTAAAAKSHGHDRNARHQTRNTIPSPRHSRPKNPPHSHTPPNRLQHHQHRSETQRLRNAYQNTAHQTPILHPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDP2</accession>
    <name>A0A8T0HDP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G104400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDP2"/>
    <dbReference type="OrthoDB" id="1930512at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051105">
        <property type="entry name" value="WWC/KIBRA_Hippo_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056440">
        <property type="entry name" value="Zn-ribbon_GIR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14791">
        <property type="entry name" value="BOMB/KIRA PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14791:SF29">
        <property type="entry name" value="PROTEIN KIBRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24747">
        <property type="entry name" value="Zn-ribbon_GIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="5">
        <location>
            <begin position="33"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="87"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="159"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="87"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="162"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="206"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="232"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="332" mass="36537" checksum="2C3D6B7D97BCDE77" modified="2022-10-12" version="1">MGIMVRERAHESALMEQRRGDESFCSEQLMPEPQLPSGWEKCLDLKSGLVYFKDWNSGTLTYRDPRRSAPVTTQRIGLLSISLSHQTATPAVKPSSNAANEGISKSLKRERSSVQEPVAHRFSSSTVRLPWDYSAATQAESPATETTTSMDEHSLELSLNLPGTSTSRPGTTSSQEGSVCTMEKVRSALERSQWLKPLPRKRASPSRESSSPVSRLHLESSSPSTSQSSASECFTSPSVMSYQGDDEEVQQPRECRDSGSKCQVLFGKQESDVSPVMVTVGCKRCLMYVMLSKSHPSCPKCGNTDVLLELPAPLPKRKRISLESPSWSWSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEA2</accession>
    <name>A0A8T0HEA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">soluble epoxide hydrolase</fullName>
            <ecNumber evidence="2">3.3.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G141500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Epoxide hydrolase involved in the biosynthesis of cucurbitacin and mogroside tetracyclic triterpene natural products (e.g. siamenoside I and mogrosides IV, V and VI). Cucurbitacins have cytotoxic properties and exhibit deterrent taste as a defense barrier against herbivores. Mogrosides are nonsugar highly oxygenated compounds used as high-intensity zero-calorie sweeteners; they also possess pharmacological properties such as regulating immunity, lowering blood sugar and lipid levels, protecting the liver, and acting as antioxidants and antitumor agents. Catalyzes the hydrolysis of aromatic epoxide-containing substrates, such as the conversion of 24,25-epoxycucurbitadienol to 24,25-dihydroxycucurbitadienol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(24S)-24,25-epoxycucurbitadienol + H2O = (24R)-24,25-dihydroxycucurbitadienol</text>
            <dbReference type="Rhea" id="RHEA:81855"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:229949"/>
            <dbReference type="ChEBI" id="CHEBI:229950"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:81856"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an epoxide + H2O = an ethanediol</text>
            <dbReference type="Rhea" id="RHEA:19037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32955"/>
            <dbReference type="ChEBI" id="CHEBI:140594"/>
            <dbReference type="EC" id="3.3.2.10"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19038"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000161">
        <property type="entry name" value="Epoxide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="8">
        <location>
            <begin position="25"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0570136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="328" mass="36824" checksum="1F497D969B95B690" modified="2022-10-12" version="1">MEGVTHRFVETNGINMHIAEQGSGPIVLLLHGYPSIWYMWRRQMQALADAGYHAIAPDQRGYGQTKGPDAEDQYTVMHLVGDIIGLLDALGQQQVLVVGHDWGAIVGWWLCLLRPDRVKGYVSVAVPALPRLAGETDWLQQWKATLGEGFYICRFQEPGRVERDFASVGTEATLKAFTCAFWDIRKGEVQRNCVAPKDKELSTVFHTGELPSWYKEEDLKYCVEQFEKSGFTGPINWYRNLGRSYKLLAPWVGATISTKAYFITGEDCAVLKFPGISDLLQGPGFKQLVPNLRGSVYIKDAAHFVMEEQPEAFNENLLTFLADLQSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HET2</accession>
    <name>A0A8T0HET2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G054300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HET2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF19">
        <property type="entry name" value="HISTONE DEACETYLASE 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="2">
        <location>
            <begin position="109"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="407" mass="45093" checksum="39AC6A3EA6884446" modified="2022-10-12" version="1">MSALWATPLRLLSSAHLPVSSYLARSPWRTLRTPALPPFESRFEVLTRGFRRLGSRQFYRSFCAGVGGVQTAEIRTDASALDESPRDGLLAFYADHYVVPLPEGHRFPMTKYRATRLLLEGDEQLRDILVTKPAPLAAIDDVCLVHDEGYVQRFISGGLTEKEQRAVGFPWSVEHRQRSLASTGGTVAAMRTVMQGKRRVSANIAGGTHHAFAGHGEGFCVFNDIAVASAICLRDYPTKCNLQTPILVVDLDVHQGNGTSKLFENDDRVITFDMHGAGNYPWKTKTKSNYDIGLPDNTGDEHYLATLAEWLPHLIELHDPSLVFFQAGVDALKEDSFGRLAMTREGLLKRNNMVYSACIERNLPLVITMGGGYSRPSDASIKAHADVYRSAALRYSAVKSRARQTPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFN3</accession>
    <name>A0A8T0HFN3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G171800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF9">
        <property type="entry name" value="PROTEIN DETOXIFICATION 46, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="450"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="484"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="565"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="632"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="700"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="29"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="767" mass="82539" checksum="F371F71693F8250A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGV3</accession>
    <name>A0A8T0HGV3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_6G175000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18579">
        <property type="entry name" value="ABC_6TM_ABCC_D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18580">
        <property type="entry name" value="ABC_6TM_ABCC_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03250">
        <property type="entry name" value="ABCC_MRP_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03244">
        <property type="entry name" value="ABCC_MRP_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000003">
        <property type="entry name" value="ABC transporter C family member 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000169">
        <property type="entry name" value="ABC transporter C family member 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000002">
        <property type="entry name" value="ABC transporter C family member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003719">
        <property type="entry name" value="ATP-binding cassette transporter, subfamily C, member 12, group MRP protein PpABCC12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050173">
        <property type="entry name" value="ABC_transporter_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056228">
        <property type="entry name" value="ABCC10-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044746">
        <property type="entry name" value="ABCC_6TM_D1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044726">
        <property type="entry name" value="ABCC_6TM_D2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223:SF108">
        <property type="entry name" value="ABC TRANSPORTER C FAMILY MEMBER 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24223">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24358">
        <property type="entry name" value="ABCC10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="477"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="577"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="978"/>
            <end position="1001"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1013"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1048"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1101"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1205"/>
            <end position="1223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1235"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="352"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="663"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="978"/>
            <end position="1257"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1294"/>
            <end position="1528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="917"/>
            <end position="953"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0570610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1538" mass="170465" checksum="B146533D3E60FC25" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH78</accession>
    <name>A0A8T0HH78_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G187500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035787341" evidence="1">
        <location>
            <begin position="18"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7381" checksum="C4716EBE9492CEAF" modified="2022-10-12" version="1">MCPKLLVLNFILSDLKLIPLCPELPESGCSTVKPICVHRNHKKITEHFYCKWIPYVFSRFVHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIC5</accession>
    <name>A0A8T0HIC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G188100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035945725" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8233" checksum="B54287E865FEF99F" modified="2022-10-12" version="1">MVGLVIPTLPTTFSLFCCSTAVARLFLSFGPCIDGISKTRNVLNPRYQLLLQVHALIYCTRMIPLHCDIEYSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJV6</accession>
    <name>A0A8T0HJV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G209600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="17650" checksum="86117FCF2CB722C0" modified="2022-10-12" version="1">MAPGSTTSFTDSHSGIKQYLVVHEASEQFKVVGSYPTEEEAYAEALDKQIDVFSTIKDSIVKEVLRSCPERSMEWKLRMLQDAMESYFMDVGFEALTDFFTVTDQPITDGAPKKRKMAVTPRGETKLAKSNTSCGIVSTARLRTMATYMYQTSPFGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKU3</accession>
    <name>A0A8T0HKU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG009700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06604">
        <property type="entry name" value="GH31_glucosidase_II_MalA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF120">
        <property type="entry name" value="HETEROGLYCAN GLUCOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="6">
        <location>
            <begin position="117"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="236"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="7">
        <location>
            <begin position="573"/>
            <end position="649"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0571412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1034" mass="115774" checksum="8A63B9773A996E54" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLB0</accession>
    <name>A0A8T0HLB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_VG026500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004930">
        <property type="term" value="F:G protein-coupled receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022343">
        <property type="entry name" value="GCR1-cAMP_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022340">
        <property type="entry name" value="GPCR_GCR1_put"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02001">
        <property type="entry name" value="GCR1CAMPR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02000">
        <property type="entry name" value="GCR1PLANT"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0297">G-protein coupled receptor</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0571606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14276" checksum="4C8A9D93DF636911" modified="2022-10-12" version="1">MLLIFVSRHCTVPHSDLLYIIRLSKGNSRAVLNSDLDARVILWIRITGMTVGALALLFAGTAFIVMCYILFKDLRAFPFKLIFYLSLSDMLGSLFNMLGYVCLPLFDELGFFSISNNASCESVRCYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLL4</accession>
    <name>A0A8T0HLL4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG035700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="10735" checksum="50EB3FFA72792620" modified="2022-10-12" version="1">MIGPDENPLGKTRAAKRSKTDGIAQDSSLVGNVSHDSSGVQEGKESSGKGKRKAASKKTSSKKGTSGEQHMSPKNVDAPEDVLSPPRASIQEPRSKKHKGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ04</accession>
    <name>A0A8T0HQ04_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG115900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9409" checksum="E7F147D3FE5AA09B" modified="2022-10-12" version="1">MFQVKLSTKPTEIQSSLQWSIVWLLLPHLQICEDVRTPGLAAYMALVHACSTSRDFAGYSIIFCSPYCHGMLMTFFNSMNIGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSD5</accession>
    <name>A0A8T0HSD5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG197500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSD5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="9234" checksum="1045585079AFA594" modified="2022-10-12" version="1">MWRGKHLHVIRRRWCLRPKTVIRERLVALFPMTCRRRRRCRNPHAYVRLKFMPLDFPAARNDLIKYQSGNLRSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVC7</accession>
    <name>A0A8T0HVC7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG280400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVC7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="18007" checksum="A4624EB42AA749C8" modified="2022-10-12" version="1">MMLKCTILRQWKLMIITEFQAVRVTMERLHSAYVMTKLEKACDLFESLPLQILHVSTCIPLQKWEYDNSYPVDGVTNVDEWAVEVCLADNVVGNGLSSIKKRRVNGMEPPKYGSSSDRIMIPSAEESTTSHSKDEEADAAEDEDSKRKGKGKQHSLDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVM8</accession>
    <name>A0A8T0HVM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG316800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="15513" checksum="5645665C22435106" modified="2022-10-12" version="1">MDTPNANTSTGLEAFRMSADTTLNHICRPPTPTTYYEISNDDPDYRRRSRDRRRSPYVHDVHLHGRGGTLLRNLTIIAWLMQSDRYQRSRHRAHKHRSLVVGVEGGVFGSPLRFWQPVSPHFHFGLRNGVLLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXB2</accession>
    <name>A0A8T0HXB2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G028900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8795" checksum="C545CC8770F2E0BA" modified="2022-10-12" version="1">MTSRSYVQPGTLSCTKPSRSTYCLKCHEMTDASFEFSSYKKTSYKYMALDTSMYQAQLLRGMNSSRQQLRRGRTRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXT3</accession>
    <name>A0A8T0HXT3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G039600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13103" checksum="5C97776F80A43376" modified="2022-10-12" version="1">MKMAVSAAAPATTVAMAGSESPSRSFGLREKFGKLHLFSVDRTNRWPVQGWSSSDESHLELDEHFVAEESARAFTLDKETRWPLQGWCKAHRPYNSTEDESAVSSHPSAPSRWPQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYH0</accession>
    <name>A0A8T0HYH0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">4-hydroxy-3-methylbut-2-enyl diphosphate reductase</fullName>
            <ecNumber evidence="10">1.17.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G025100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="8">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the IspH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.4" evidence="10"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYH0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051745">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-enyl diphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003451">
        <property type="entry name" value="LytB/IspH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31619">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31619:SF5">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02401">
        <property type="entry name" value="LYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00046335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0575711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="19618" checksum="25C90CE9FC43863B" modified="2022-10-12" version="1">MAAVACQSSAILLSTSLYGQRVDSSSPSSSVRWLVSRRPCSFPRCCNASHAADEFDTKEFQFKLMRGEKYNRSGYGYKKGMLKQMDVEYTSDLVKTLKENNFEYTWGNVTVKLANSFGFCWGVERAVQIAYEARKQFPDQKLWLTNEIIHNPTVNKVGGLLFCFGMFAIAQKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0D7</accession>
    <name>A0A8T0I0D7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Epidermal patterning factor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G093400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0D7"/>
    <dbReference type="OrthoDB" id="1937916at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010374">
        <property type="term" value="P:stomatal complex development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039455">
        <property type="entry name" value="EPFL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109:SF4">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17181">
        <property type="entry name" value="EPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035724485" description="Epidermal patterning factor-like protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="54"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0576606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="158" mass="16934" checksum="2B9ED8C01AC2A57A" modified="2022-10-12" version="1">MEIGTCCSLLLLLAVYPLQTIAGRQLSATSPATLVQTPPLVQVPAAPAMCQGSKGEVGGRSMLEDDAQFQDRSPPPHRKTSRQGKHSKQVKGDDHGESIYGHRLLVGSSAPTCQGKCGQCNPCSPIHMAIGSPHGALTQQEYYPEVWRCKCGGIYFMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2E7</accession>
    <name>A0A8T0I2E7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fungal lipase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G133100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2E7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="1">
        <location>
            <begin position="76"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="763"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0577129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="952" mass="105324" checksum="0E318D6FB117D188" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3J8</accession>
    <name>A0A8T0I3J8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator of RNA polymerase II transcription subunit 33A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G162300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="683212at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000762">
        <property type="term" value="P:regulation of phenylpropanoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039638">
        <property type="entry name" value="MED33A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33739">
        <property type="entry name" value="OS07G0681500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33739:SF3">
        <property type="entry name" value="OS07G0681500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1308" mass="140132" checksum="3B22341093AB93EA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I707</accession>
    <name>A0A8T0I707_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G088600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I707"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="16195" checksum="8513057B29A7209E" modified="2022-10-12" version="1">MATLNTLSIASAAPLHRHSPQRHRLRTPSTLLTGQGRLAGVRDWHVGSKVRVALGDGAREGADEVWCGLCGDRGGWLMCGRCMGEGGFPTRPGLAGVKGKVGWGRCKTCFGRKVVPCLFCGVSDVAEWKLWVENAKRHPHRSRKQVDVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9J3</accession>
    <name>A0A8T0I9J3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G142500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9J3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="51200" checksum="C47F3570752E55CB" modified="2022-10-12" version="1">MTSLCCNRTTGQEVKYWVYATREDDSERKWWSSFDQKIGNYLEDFDAERPLQKEYARGRPFVRLLVILAMIIAFGIGAWLIYQDASNIRIQRFYLDKHEDYATQRLFNKSVSYGTLVDAEKKTRNSTNSSDAPEFIDCPCRNKTFSWTAYTHFYTLNYTPPGDTPALNYILDNTTGSITALSDNRGTVDPKYLFRNQSNQLTRDEFCAFAISILPKEYTISSAYLDCPGLVASFFTTDPLPETPGNSRSRWNNPQASNFDSPLLLSQELLYSKTLQNLYAYIQAQYSRLESMRPFTFDNKTYRDMYLTGISEIWLNVLDTFTRNSSASDLDFYMYASGTTIAMFYDRNVAYPEGEQYWEVLLYEGQTFLGMDINWMDYYKACNPSYCDVTKSNPWFRRLYIALAQIGGLITVVGMLVKLVIFPAVLFMLTRMFCCSRGTSRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBM3</accession>
    <name>A0A8T0IBM3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G170200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBM3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="489"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="176"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="58058" checksum="243042596005F271" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBU1</accession>
    <name>A0A8T0IBU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G207400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02999">
        <property type="entry name" value="PDI_a_ERp44_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044606">
        <property type="entry name" value="APRL4/6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46854">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE-LIKE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46854:SF1">
        <property type="entry name" value="5'-ADENYLYLSULFATE REDUCTASE-LIKE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="9">
        <location>
            <begin position="57"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0580882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="40480" checksum="DEC69FFC21A915E1" modified="2022-10-12" version="1">MMYFRCASSHTIQKVISICGFLCLIVVVSLASAAADSLSTHPVILPHCSAPTLEESFLQESPVPDFCRSSSQECPSKYHHVASGRPQSTRVAELNETTLEKALDLVHSSNGTYIAVLYYATWCPFSRQVRPVYDVLSTIFPTVHHVAVEESSVRPSVLSQYGVHSFPILFMHNRTARVRYYGPRNLEYLIRFYQNYTGLNATEDEPSRKEDCAFARLVYNAGTDAKEACPYPWAISPEKWLQDDMYLNLAVVFLVLRLVYFLVPALVLRLKQRWVNGNFTVMPLRANYPVPSNEESSLLGNASQVGDEADDKTLGDGTANGLNNVFIPSGPPAQATPQASSPAVAESSSSRAGPSGEAQDMGGKHMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDH5</accession>
    <name>A0A8T0IDH5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">XPG-I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_3G010000</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">5'-&gt;3' double-stranded DNA exonuclease which may also possess a cryptic 3'-&gt;5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="20">Interacts with the MLH1-PMS2 heterodimer via MLH1. Interacts with MSH3. Interacts with the MSH2-MSH6 heterodimer via MSH2, and this interaction may increase the processivity of the 5'-&gt;3' exonuclease activity. Interacts with PCNA, and this interaction may both stimulate the cryptic 3'-&gt;5' exonuclease activity and suppress the 5'-&gt;3' exonuclease activity. Interacts with WRN, and this interaction stimulates both the 5'-&gt;3' exonuclease activity and cleavage of 5'-overhanging flap structures. Interacts with RECQL/RECQ1, and this interaction stimulates cleavage of 5'-overhanging flap structures. Interacts with DNA helicase ZGRF1; the interaction is increased following DNA damage induction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035312">
        <property type="term" value="F:5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002376">
        <property type="term" value="P:immune system process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051321">
        <property type="term" value="P:meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09908">
        <property type="entry name" value="H3TH_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09857">
        <property type="entry name" value="PIN_EXO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.20:FF:000011">
        <property type="entry name" value="exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000111">
        <property type="entry name" value="Exonuclease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037315">
        <property type="entry name" value="EXO1_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044752">
        <property type="entry name" value="PIN-like_EXO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019974">
        <property type="entry name" value="XPG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081:SF65">
        <property type="entry name" value="DNA DAMAGE-INDUCIBLE PROTEIN DIN7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="FLAP ENDONUCLEASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00842">
        <property type="entry name" value="XPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="16" id="KW-0234">DNA repair</keyword>
    <keyword evidence="15" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0391">Immunity</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="18" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPG-I" evidence="21">
        <location>
            <begin position="79"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00057694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00064664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0581794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="29611" checksum="1AE2EEC862569F80" modified="2022-10-12" version="1">MHRVNMLRHFGVQPVLVFDGGSLPMKSDQEIKRARSRKDNLERAVEHERLGNHSAAIECYQKAVDITPALAFRLIKVLRQENIEYVVAPYEADAQMAFLALNGNVDLVITEDSDLIAYGCPQIFFKMDKYGQGVGFQFSDITANKDLDFNNFSKRMILEMCIMSGCDYLRSLPGMGVKKAYGLIKRFKTYQKVLKHLKFSGVMIDQQYEEGFQRAVLTFRHHRVYDPAKSEMVHLTDVPSELDSDLDFLGPYPLFGSHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHF7</accession>
    <name>A0A8T0IHF7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G115500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHF7"/>
    <dbReference type="OrthoDB" id="10255013at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15848">
        <property type="entry name" value="SNARE_syntaxin1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00179">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000003">
        <property type="entry name" value="Qa-SNARE, Sso1/Syntaxin1-type, SYP12A-group"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000008">
        <property type="entry name" value="Syntaxin 132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF251">
        <property type="entry name" value="SYNTAXIN-RELATED PROTEIN KNOLLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="8">
        <location>
            <begin position="212"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="49"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0583180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="310" mass="35318" checksum="3581F9594F9BD48C" modified="2022-10-12" version="1">MNDLLSQTFSARKNGRGPYDDDLESGGGPSTQMADLGGDLKLERFFAEVEKIKTDMDRIKQLLLKLQEANEESKGVHRAPAMKALRGRMDADIAQVSKLARGIKAKLEDLDRGNAESRRVKGCEEGTPTDRTRMSITNNQRKKLKDLMGEFQGLRETMMNEYKETIERRYYTVTGQQADEETIETIIETGQSESFLQKAIQEQGRGHVMETIREIQERHDSVKEIEKNLLELHQIFMDMAVLVEAQGEQLNNIEAQVNRSASYVERGNAHLVVAKRHQRSKRKWTCIAIILLIILLVIIIIPILKTNKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIM5</accession>
    <name>A0A8T0IIM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Target of rapamycin complex subunit LST8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G149600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WD repeat LST8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIM5"/>
    <dbReference type="OrthoDB" id="400at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031931">
        <property type="term" value="C:TORC1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031932">
        <property type="term" value="C:TORC2 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032956">
        <property type="term" value="P:regulation of actin cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000179">
        <property type="entry name" value="Target of rapamycin complex subunit LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037588">
        <property type="entry name" value="MLST8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842">
        <property type="entry name" value="G BETA-LIKE PROTEIN GBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19842:SF0">
        <property type="entry name" value="TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="115"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="207"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="5">
        <location>
            <begin position="253"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0583620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="316" mass="35302" checksum="4C7BE781BADA71FE" modified="2022-10-12" version="1">MPHPSVVLATAGYDHTIKFWEATSGRCYRTLQYTDSQVNKLEVTPDKQYLAAAGNPHIRLYDVNSNHPQPVLSYESHLNNVTAVGFQCDGKWMYSGSEDGTVKIWDLRAPGCQREYESRAAVNTVVLHPNQTELISGDQNGNIRVWDLTTNSCSCELVPEVDTAVRSLTVMWDGSLVVAANNNGTCYVWRLLRGTQMMTNFEPLHKLQAHDKVVLKCLLSPEYCEPNKYLATTSSDHTVKIWNIFDFSLARTLKGHSRWVWDCVFSVDGAFLVTASSDTTARLWELSTGEAIRVYQGHHKATVCCALHDGTDPSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIU1</accession>
    <name>A0A8T0IIU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G089400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101005">
        <property type="term" value="F:deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF80">
        <property type="entry name" value="IP06716P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="4">
        <location>
            <begin position="16"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0582829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="282" mass="31792" checksum="9E9C215A7EB58DEB" modified="2022-10-12" version="1">MTAPECPKGSDPNREEPIYLNVYDLTPMNGYVYWVGLGIFHSGIECHKAEYAFGAHDYPTSGVFEVEPKHCPGFTFRRSVQLGTTSLNAAEFRSFIEQCADEYYGDTYHLIVKNCNHFSEDVCKRLTGKSIPGWVNRLARVGYMCNCLLPEGLQVTATEVPECQAPSTEAVRDFAEGKEMMESESDQERALITTPSGNTQALMRDSFKERIGDHDHVLLTCSRENTQTVLQPPELSATPSQVLRDGVKSRDRASKNPHWFGSFDGLWHWPLMEVFTFTDESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKF5</accession>
    <name>A0A8T0IKF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G197400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000001">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663">
        <property type="entry name" value="GEO12009P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45663:SF22">
        <property type="entry name" value="THIOREDOXIN X, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="63"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0584260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19662" checksum="0FF539F7ACF2C3D8" modified="2022-10-12" version="1">MMQAVVAQGVGTCGFVKSRDVGDVVPVRSSLMVSSGLRQVSWRRQGHGGGRMVAEVRRERKGLGVRCKVMTVTEESFEAEVLKSELPVLVDFWANWCGPCKLVATSMDVVDRKYEGKLKVVKVETDPNPKLVEAYKVYGLPTLIMFRDGKVISGGRYEGAISLAKLESMLKKALPSLAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILC4</accession>
    <name>A0A8T0ILC4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine kinase/HSP90-like ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G156900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16927">
        <property type="entry name" value="HATPase_Hsp90-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000005">
        <property type="entry name" value="Heat shock protein 90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="HEAT SHOCK PROTEIN 90 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0583707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32332" checksum="1AB243EF504F8569" modified="2022-10-12" version="1">MHQLVSSYLPLGEYTRLSPAQGLLWFLTMAQFAAVTALCVLLTLSSIHVQDFHVGVNAREENNVEENVGTFAKVEERIGAVPSGSTTDAELVQREHDSMLRKRSNSESFEFQAEVSRLMDIIINSLYSNKDVFLRELISNASDALDKIRFLSLMDKSLLGEGDVAQLDIHIKMDKEKNILSIRDRGIGMTKEDLIKNLGTIAKSGTSSFVDQMKKGDDLNLIGQFGVGFYSVYLIADYVEVISKHNDDKQSWCKDTLSSLVFQYTCGQARRSRMKSMTKRQLLRKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMU2</accession>
    <name>A0A8T0IMU2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G168600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14194" checksum="5CEE757ADCAE9BA0" modified="2022-10-12" version="1">MRGTLALVVSRLVSSAFSSERAAVSELLCYFLSEYVHSFCHQKSSGRRVFDASRTVDMLLQLFCLLFCCDSMSVGGIAISRIVLWIRYCVPVTRSRCCVSALCATCNVRVSSDLAYIRHHVICLIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN27</accession>
    <name>A0A8T0IN27_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G208500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IN27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="17205" checksum="E2B3995A5ED1DFBE" modified="2022-10-12" version="1">MFLMLYMAGSVVESAATGRAILSVNSNDSMGATARNQETVLQWVQITVVPLGVFLLGACIWGIIQHTAASLGNSFTGFGEGQPETDNQVSTENHLISNVRVAQDLEEGLQVPNRRMDVDGRTETLNSPIDAREYGMQPEFNVSNNEGITSAGRTMQTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INY3</accession>
    <name>A0A8T0INY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mitochondrial inner membrane protease ATP23</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G229900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M76 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INY3"/>
    <dbReference type="OrthoDB" id="285308at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034982">
        <property type="term" value="P:mitochondrial protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033615">
        <property type="term" value="P:mitochondrial proton-transporting ATP synthase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019165">
        <property type="entry name" value="Peptidase_M76_ATP23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21711:SF0">
        <property type="entry name" value="MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09768">
        <property type="entry name" value="Peptidase_M76"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0584715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="191" mass="21379" checksum="FCD3CC04721BD4EC" modified="2022-10-12" version="1">MEETASSASNDGYPTGTTPEHCQHMINHSLSRNATVKFVREALTKAGCPVADKFFKPEHCSMKVGGGFKQDDGIVICSNNVTHQDEVDVALTHELLHAYDHCRAANLNWTNCEHHACSEIRAANLSGDCAWKRELLRGNTNIQKQHQICVRRRALISVGLNPHCSMHRAISAIDRVWKTCYNDTQPFDRVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPB8</accession>
    <name>A0A8T0IPB8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Phosphoinositide phospholipase C</fullName>
            <ecNumber evidence="3 8">3.1.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G239900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1D-myo-inositol 1,4,5-trisphosphate + a 1,2-diacyl-sn-glycerol + H(+)</text>
            <dbReference type="Rhea" id="RHEA:33179"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17815"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="ChEBI" id="CHEBI:203600"/>
            <dbReference type="EC" id="3.1.4.11"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.11" evidence="3 8"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPB8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004435">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate phospholipase C activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051209">
        <property type="term" value="P:release of sequestered calcium ion into cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00275">
        <property type="entry name" value="C2_PLC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.150:FF:000328">
        <property type="entry name" value="Phosphoinositide phospholipase C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="entry name" value="Phosphatidylinositol (PI) phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001192">
        <property type="entry name" value="PI-PLC_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000909">
        <property type="entry name" value="PLipase_C_PInositol-sp_X_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001711">
        <property type="entry name" value="PLipase_C_Pinositol-sp_Y"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336:SF36">
        <property type="entry name" value="1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10336">
        <property type="entry name" value="PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00388">
        <property type="entry name" value="PI-PLC-X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00387">
        <property type="entry name" value="PI-PLC-Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00390">
        <property type="entry name" value="PHPHLIPASEC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00148">
        <property type="entry name" value="PLCXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00149">
        <property type="entry name" value="PLCYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="PLC-like phosphodiesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50007">
        <property type="entry name" value="PIPLC_X_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50008">
        <property type="entry name" value="PIPLC_Y_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <feature type="domain" description="PI-PLC Y-box" evidence="11">
        <location>
            <begin position="375"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="10">
        <location>
            <begin position="464"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="282"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0584857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="617" mass="69392" checksum="C07518A622F65968" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRK8</accession>
    <name>A0A8T0IRK8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G000400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRK8"/>
    <dbReference type="OrthoDB" id="687495at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048766">
        <property type="term" value="P:root hair initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11454">
        <property type="entry name" value="bHLH_AtIND_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000046">
        <property type="entry name" value="Transcription factor bHLH83"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045843">
        <property type="entry name" value="IND-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914:SF59">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH83-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914">
        <property type="entry name" value="TRANSCRIPTION FACTOR HEC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="708"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="429"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="552"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="804"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="432"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="485"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="505"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="552"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="624"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0585278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="826" mass="89112" checksum="C56FFB15563388BB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRV4</accession>
    <name>A0A8T0IRV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G260400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="3996" checksum="DE4DD91875044583" modified="2022-10-12" version="1">MDAGFSLDFTKIRNPGEESWLLGYCISGCHDVACRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS54</accession>
    <name>A0A8T0IS54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G099600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="80" mass="9195" checksum="9761DA3654CBA765" modified="2022-10-12" version="1">MRHESRTDCKYDQNGPKTELCQNCLILGHRLTEREAEELERLVGCGRVILFVCNLCVDGGDRQSELRDEPEMSRQQMPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IT01</accession>
    <name>A0A8T0IT01_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 18">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="12">IMP dehydrogenase</shortName>
            <shortName evidence="12">IMPD</shortName>
            <shortName evidence="12">IMPDH</shortName>
            <ecNumber evidence="12 18">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_2G039100</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12 18">
            <text>IMP + NAD(+) + H2O = XMP + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="12">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 18">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12 17">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="12 18"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IT01"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04601">
        <property type="entry name" value="CBS_pair_IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000086">
        <property type="entry name" value="IMP dehydrogenase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911:SF111">
        <property type="entry name" value="INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01240">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51412">
        <property type="entry name" value="Inosine monophosphate dehydrogenase (IMPDH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0129">CBS domain</keyword>
    <keyword evidence="12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 12 18" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 12 18" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 12 14" id="KW-0520">NAD</keyword>
    <keyword evidence="7 12 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 12 15" id="KW-0630">Potassium</keyword>
    <keyword evidence="5 12 18" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="114"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="19">
        <location>
            <begin position="177"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="12 13">
        <location>
            <position position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12 13">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="273"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <begin position="323"/>
            <end position="325"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="325"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="12 15">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="386"/>
            <end position="387"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="410"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="438"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0585788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="53622" checksum="87476C58A88B0BE6" modified="2022-10-12" version="1">MASEGYANGDYGVMSDGFSAGALFKQGFSYTYDDLIFHPGYINFAVDDVDLTTSLTRNIKLRTPCVSSPMDTVSEESMAVAMAAVGGIGFVHYNNTAQEQAGIVRRAKKQRVGYVASPVCVRPSDSISIIDALKAGRGFSSVVVTEDGAVGSRLVGIVTSRDVDFVRDRSTEVREVMSRDLVTAPAGTSLEEAAKILIGSKKSLLPLVTESGEFVELLCRTDLKAYHELPPLGAPSLGSDGKLLVGAAIGTRDSDKDRLKLLVEAGVNVVILDSSQGDSMYQRQMIEYIKKAHPGLDVIGGNVVTGYQAKNLIDAGVDGLRVGMGSGSICTTQEVCAVGRGQGTAVYKTAAVANALGVPIIADGGISNSGHVVKALSLGASTVMMGSFLAGTDEAPGNFFFQDGVKLKSYRGMGSLEAMTKGSDARYLGDKTRLKIAQGVSGSVAAKGSVLRLVPYTLQAVKQGLQDLGVSTVKAAHDGLNAGVIRLEVRSGAAQKEGGIHDLVSYEKRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IT80</accession>
    <name>A0A8T0IT80_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G053100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IT80"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000023">
        <property type="entry name" value="protein REVEILLE 6 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF146">
        <property type="entry name" value="PROTEIN REVEILLE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="14"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="8">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="80"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="542"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="396"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="583"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="600"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0585971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="676" mass="71931" checksum="95FDE4407BB35790" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITZ4</accession>
    <name>A0A8T0ITZ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G067400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITZ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11450" checksum="B02824133001940C" modified="2022-10-12" version="1" fragment="single">MGRRAREQVSLLQPVLRGAEFLFLAFRSDGSQSGGAARWRAISWSEWISIGGEEEEGEGGGEGEESVLVVVLLSSRAARGCRGKWCARDYGFEVGEGGWRVVVGGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXC9</accession>
    <name>A0A8T0IXC9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G195700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="15207" checksum="A826B75401AEC64C" modified="2022-10-12" version="1">MVMGRLARRQALDPRGSTGGRGHGWADGGEGGMKQAGVCVPYEHSMRLPLSSLAKPALGQPQAHRHLPSPPPPPHRISRIHPPAPPPPSPPPGYWKCVGDLLPVWIWRGSIAITWWLKIGLFAICVVVCCGICDYASELEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXJ4</accession>
    <name>A0A8T0IXJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G166400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="13526" checksum="BA93B397D4EB5FD5" modified="2022-10-12" version="1">MVTRHEVHSLTGWVLRSGCQPQVAPLAPSVHLLLECNVPEFSFLITSPCRRGHVGIAVAGAFVHIAGAGVVATVGSGLAGRSGHSHHAGETVITHRVIEPHTLIARASRLAAALGAAPASISARHDEVFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J017</accession>
    <name>A0A8T0J017_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G206100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J017"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035824940" evidence="1">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5547" checksum="9C5EBD970A6C1C61" modified="2022-10-12" version="1">MAIHYRDIMGVLLLMLVATGESCAVSGLRAELYWLGFRNRGKKFSLRTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J024</accession>
    <name>A0A8T0J024_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G253400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J024"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11472" checksum="00C6704AC61F5133" modified="2022-10-12" version="1">MMVLIALRSFWSEFLKCRPGCMFGAASRGVLHNPLSYLCKIRARLCESLSFQESMKKLIFAFLPEVSHGCVHDGNCVGFEYYQKNNKHLGRWFPDQHRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0B0</accession>
    <name>A0A8T0J0B0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G259700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0B0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="125"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="35068" checksum="D63C7861312C885C" modified="2022-10-12" version="1">MGNTNSCVRHLPDVFCVCMGRSSEAGDVAGSAAEDAASSPSPHLANRSASNYLVGEVSSESVAQQIEQSKSHWSDLRVFDSDCIEEDVEADNMEVFLALQSHPTWCHFFRTFGYDTEVAYSDGSLEIGHKFAEGGQAELFHANVTWSDLKASEWDREHGREWVLKVFKKGTRLRHLQSQWPHGMLKYRMEQAANWKSPTPKQIPRFHCSVHCGTLLEDGRFAFLMKKEHLDLRRLIDDKMKLISPNKCGPFSKEVAEELMFDVALGMSWLHSRDIVHRDLKASNVLVKVHVDGQFQCFVADYECSIGVVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J110</accession>
    <name>A0A8T0J110_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Activating molecule in BECN1-regulated autophagy protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G263200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J110"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080008">
        <property type="term" value="C:Cul4-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990756">
        <property type="term" value="F:ubiquitin-like ligase-substrate adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000423">
        <property type="term" value="P:mitophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:001735">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052596">
        <property type="entry name" value="AMBRA1_autophagy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22874:SF1">
        <property type="entry name" value="ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="152"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="370"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="550"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="12"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="567"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0588706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="922" mass="97582" checksum="F1EDCA6A5BD6F3F3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1N7</accession>
    <name>A0A8T0J1N7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G279900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1N7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044197">
        <property type="entry name" value="FKBP17-1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47860">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47860:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP17-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="38"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17355" checksum="E88064A5EE40B82B" modified="2022-10-12" version="1" fragment="single">MVTSIARADDVKFYELAGSSGVKALHIRQGTGVSPEDGDRVEVHYYDRPFAKQGWRFDSTYDHKDFFGNPEPYVFTVGVGSIIGGMTSAVRNTKEGGVRRVVIPPSQGYQNTSQGPIPPDYFDRQRLYTTIFNQTRLANGEGDTLGTLIFDIELLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2F7</accession>
    <name>A0A8T0J2F7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CWF21 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G047400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CWC21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2F7"/>
    <dbReference type="OrthoDB" id="10267305at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051372">
        <property type="entry name" value="CWC21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013170">
        <property type="entry name" value="mRNA_splic_Cwf21_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562">
        <property type="entry name" value="SERINE/ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36562:SF5">
        <property type="entry name" value="SERINE_ARGININE REPETITIVE MATRIX 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01115">
        <property type="entry name" value="cwf21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="CWF21" evidence="8">
        <location>
            <begin position="110"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="151"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="203"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="203"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="269"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0589775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="471" mass="57443" checksum="3337774CA110BCFC" modified="2022-10-12" version="1">MRACGRVLVEAFTSFTHTQDSSFVCSRVCSTATVFVVNFVAGESACGECVRNFTMYNGIGLSTPRGSGTNGYIQTNKFFVKSRPVRSEAKEFQTGQGAGGVLRKANKDILEHDRKRRIELKLIELEDQLVDQGYPDEEVLERVEELRKRLDAAGGDDGDDASAGLDSRGNSTQSHHIAAQKEKQLETMRSALGLKEVKEGEAFDRDLQEQKKQERIMAREEKDRERRDKQAAIEEEEKRLKKEQRREEKLRLREQEEEEHRQRKRERKARREQEEEERQQRKKEAREKREHEEEERHQKRKELREDREPEDEERHQKKKESREKREPEDEERHERRKESREKREPEDEERYEKRKELREKREPEDDERYERRKESREKREPEDEERYQRRKESREKRETDDEERPYKRRETREADDEERPHKRREADDEERPHKRREIDDEERPHKRREAREVEDEERHQKKKERRERREH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3A9</accession>
    <name>A0A8T0J3A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_1G040900</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3A9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000101">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000146">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase IOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF77">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="302"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="371"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="648"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0589702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="670" mass="73585" checksum="10C616B3A235F333" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3D7</accession>
    <name>A0A8T0J3D7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PHL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G028400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3D7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060962">
        <property type="term" value="P:regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046467">
        <property type="entry name" value="PHL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20474">
        <property type="entry name" value="PHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHL" evidence="3">
        <location>
            <begin position="86"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="338"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="536"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="633"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="741"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="298"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="344"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="536"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="741"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="766"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="823" mass="89071" checksum="6E02720EEE45C0EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3V5</accession>
    <name>A0A8T0J3V5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G021000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3V5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0589443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="288" mass="32483" checksum="810988C268D1C1FD" modified="2022-10-12" version="1">MWFHVDGAYAGNACICPEYRPHLNGIEKADSFNMNPHKWLPTNFDCSTLWVQNRTLLQAALGIYPVYLRNKLSDNGLVVDYKDWQIPLGRRFRALKLWMVMRMYGSSGLQSYICNHCDLAKHFEKLLRTDSRFEVMAPRMFSLVCFRLRPPPNDADNGYALNAMLADALNSDGSILVTNTIRILLPACFLDSLTMCCSLLHEILIPHCLIDGRMRSCCAGSGRSLHYSVCYWWIANGVAACRVCLESYSVASLQVSCGLMERVWITSSLVGMIPSRLTRGSSIEFLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4C3</accession>
    <name>A0A8T0J4C3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G101700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4C3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="128"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="960" mass="108091" checksum="67957AD1859D28B5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5S8</accession>
    <name>A0A8T0J5S8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biogenesis of lysosome-related organelles complex 1 subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G138300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BLOC1S2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5S8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019269">
        <property type="entry name" value="BLOC1_su2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47882">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47882:SF1">
        <property type="entry name" value="BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10046">
        <property type="entry name" value="BLOC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="204" mass="22801" checksum="CBD42315FDBECC31" modified="2022-10-12" version="1">MVVSSNHRNKCWKPGHCYQFCTNPWKRLSHSQECSVELFDNQHQGLCFLDLGLGFMEDSEAVAAPASAEETTSEIPPPSPSPSPSTASPSSYDPLAKALQTLFLNVTTVVQGELQAVNSEYELLERMNLRVASEHDHQAEFAQGLRVFVENLKEKNDGFSEYIQQIDEIDQEVTELEALVSTLDNYTSNLESKLRIACARPHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6W4</accession>
    <name>A0A8T0J6W4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G191000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6W4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035847068" evidence="1">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11554" checksum="4D7B2C54450DBC45" modified="2022-10-12" version="1">MEILFVMLLCIQGLVSHLDSGVSSLAAMDLEYFITRNRNRTHPPTWSSGVLALRRFLRDEALAFLHMLGFVVGWVVDTLDDLFRYRVLLSMVRCCADRCST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J711</accession>
    <name>A0A8T0J711_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G124400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J711"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="177" mass="20251" checksum="D6949D9424E6CC28" modified="2022-10-12" version="1">MSPAKQPNEVQPNVTCPIIEATTMDICLHCYLHQHSYTNEEENIQAIEFVEITKNLQPMFRDWTEEQQSGIDVKYLYRLPSPTRAFQNGAISKSAPTSLSRASPKRLPSHTSEILRRYRRSIKHRRQELANPRRVSTKVVGALHQLRREKDACIKVLIANAQTSLIANASTSLERGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J966</accession>
    <name>A0A8T0J966_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G237400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J966"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37766">
        <property type="entry name" value="OS01G0897100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37766:SF1">
        <property type="entry name" value="OS01G0897100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="455"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="518" mass="59924" checksum="564CCEFEAE36F716" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9V4</accession>
    <name>A0A8T0J9V4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G210600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9V4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035812754" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="106" mass="11917" checksum="D9BF1D522E351C50" modified="2022-10-12" version="1">MTSRLYCLLSCSLLQSCVGTLPTISTTSTWCWLHINAGEVESNGLEVLHAPRSSSKTPQTILVLGERDRTSTSMLRRIQVSMRWSMPFVIAKWRRTGMVLVNVETC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAU6</accession>
    <name>A0A8T0JAU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G205500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12030" checksum="DDB4225A48461D27" modified="2022-10-12" version="1">MISLDLGLSSTSRLPNPSVPLPLVLPFKEPRIRMALRLAGCNFHFFQFKFVLVMQFWLKFISRSSTWKGQLLVVEHNACLQALKPVSILYNLKQEDDSRVANLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4C9</accession>
    <name>A0A8T0G4C9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G062900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4C9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="157"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="19557" checksum="3E6EB6903A1BF338" modified="2022-10-12" version="1">MAQVPQNAGTGDYVKAPEQYQREMPIGEQLVQLKDTVKGNINQFADQANIHYDQASNDPANPASDDRLARDLDTTAQHAATSVETAKGQVARAVDAAAQTAQSMKGAFVATKNQGTATPTSPNLPQQPPAAPAAQSVSESLGQTAATVTDAVKNFFTPRQTTPGTQPGMDNITTNMPQDVPRSAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8B6</accession>
    <name>A0A8T0G8B6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Two-component response regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G140700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8B6"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
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        <property type="component" value="Chromosome 12"/>
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    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17584">
        <property type="entry name" value="REC_typeB_ARR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045279">
        <property type="entry name" value="ARR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874:SF137">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ARR11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="75"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="264"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="210"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="587"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="225"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="249"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="587"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0555055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="714" mass="75345" checksum="F041F054B9936BB8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8H0</accession>
    <name>A0A8T0G8H0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G179300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8H0"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009707">
        <property type="term" value="C:chloroplast outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052615">
        <property type="term" value="F:ent-kaurene oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016709">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010241">
        <property type="term" value="P:ent-kaurene oxidation to kaurenoic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009686">
        <property type="term" value="P:gibberellin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11075">
        <property type="entry name" value="CYP77_89"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044225">
        <property type="entry name" value="KO_chloroplastic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47283">
        <property type="entry name" value="ENT-KAURENE OXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47283:SF1">
        <property type="entry name" value="ENT-KAURENE OXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0349">Heme</keyword>
    <keyword evidence="6 7" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0555576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="61520" checksum="7C29C69508AF7B42" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC20</accession>
    <name>A0A8T0GC20_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G119500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC20"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="407" mass="45397" checksum="46FDBAAF8245E19E" modified="2022-10-12" version="1">MEVWDLAPGESISQDGSLRAFRYSEFTECPSAPFNTAEIEFLPSQVRCSDSLTTSLLLGSERCEYKKEEPSGGISSDLLCSLRDVDAPEEGNGSDFREDVQSGSSFSDSLGLSLADECRESKERESSPRRVFCDPRLLEEETQVAADNVVPFPSQQDSHLLFSNQHLHSAPQAFECDDVTEEIDLPSHRKDASEGILTTAAESPKSPLFETKQEDVCASTASDQKKFAAVLEDCDDIVQRWHNRKRVARAASNHQGSSLNAGIPKKLKQATEIKVESGTLHPNQPQDDQPQDDQPQDDQPRDDEPQDDQPVKIPMINDQKNCEQLPVTPPLSSDAKSSEKDIGAIAETDDVSESSFLRRKLNYSCSRDIKTFWQPEASPKQVEEGKWSCPRKYRPGGRQRTMDAWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCM8</accession>
    <name>A0A8T0GCM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G057100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="18445" checksum="A5067145957A4E64" modified="2022-10-12" version="1">MTPIPHLLKKAKFSISRSSSTPSENLPLTSSFQPRRPQRKLAPAREWTAPATTRRSEWAQEPALAPSQPIPWWRPPRPRRRRLSSQLTKLKPFQQSGLTRTREGVIRNVMKRGEVQWREGDAVLRAVRSDQASRAAMARDAAQPGRQLWRAAAKLLRSPLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD45</accession>
    <name>A0A8T0GD45_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G121300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050655">
        <property type="entry name" value="Plant_B3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920">
        <property type="entry name" value="B3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920:SF108">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR VRN1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="70"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0557336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="20321" checksum="2A2A8A4FD0044E35" modified="2022-10-12" version="1">MCSQIVTMVRPKSDSSFVDDWKSILEPDLDAIAYNGATCDPTRVDPKVLDWVRENCGESPRFVKVINRNAANGRPGLLSGSSTSLAVPGPFVRENFRNLQRVVTLDNGHGRKWKVSFKSVGSRAPVWLRGWRNVARDNNLKPGDVMVFELVGKSHFHITIFDEDGNISHDSTSRLKNAGREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD77</accession>
    <name>A0A8T0GD77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G056200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1500">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="212"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="6"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="217"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="29535" checksum="FD86A580715D4824" modified="2022-10-12" version="1">MDKGKRAKVEEEESELDAELVQAIEKLQEVQDELERVNEEASDKVLEVEQFYNEIRRPVYSKRNDIIHNIPDFWLTAFLSHPVLCDLLSDDDQKVFKYLESLDVEDFKDVKSGYSISFNFRANPYFEDTKLTKIFKFSDEGTTSVSGTQPKWKAGMDLTNGVLPEKEGLKRPLVEESFFKWFSDTTQKLSLDGIQDEVAEVIKDDLWPNPLKYFNAEPDEDGFESGEQESGDEEEGKGDGLDGEDDEPDEDDEDDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG88</accession>
    <name>A0A8T0GG88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G146100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="175"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="452" mass="49546" checksum="4892BEC51C031098" modified="2022-10-12" version="1">MKFFGWGKNKDPQPQTVLQQANKPDARSGSHGPLDRCKSLSGMGSIMPNKGSSTTGMRKQQGLFGVEEERGLLSSARMPKVSSDDAADSEEKLQDKIRFVFSHEREGLLAIGTFALEQLQSIRNTIDGHLNATSEDGLDSSASALDDIMQSSDDEDQLQRSWIAARKTCDLPVFGDSVDTSGVESEAEKPPRYSDRDDSKALALYKPNPDPNTDSSSVKPVVLLTGLPPEIRRALDPATALLYGKSFLPHWTDAVPPPVLAKPPAPFVDEDYYSSRLCGLFSRKKSLSKSKRHDNQGQIVPAAGEEKKRLIPIELAAQETKKSILNFAAPGVPSIGKLAKLWRASCKQSTARIAPERRSPSPVKDLPAKGQACANVFASDEVLTAPELQVMRPSIGLPAGACSPKVAEFRKRVQMHERMLNAPGEFRDSFESSRDDYGHWIKDDEDFLVLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH93</accession>
    <name>A0A8T0GH93_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Phosphoribulokinase</fullName>
            <ecNumber evidence="15">2.7.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_11G138300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14 15">
            <text>D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19365"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57870"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; Calvin cycle.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the phosphoribulokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.19" evidence="15"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH93"/>
    <dbReference type="OrthoDB" id="738517at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008974">
        <property type="term" value="F:phosphoribulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02026">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000619">
        <property type="entry name" value="Phosphoribulokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006082">
        <property type="entry name" value="PRK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF005655">
        <property type="entry name" value="PRK07429.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00478">
        <property type="entry name" value="PHRIBLKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00567">
        <property type="entry name" value="PHOSPHORIBULOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="16">
        <location>
            <begin position="79"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0557539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="423" mass="46284" checksum="C8FC5BBFC6AEA3CF" modified="2022-10-12" version="1">MAAMACTHAASTAVTTPRLGAVKATSSKPVRAVQLGSSFHGQGVASCSQVAGLRSRASGVSTGRRAVVVCKAADGQTVVIGLAADSGCGKSTFMRRLTSVFGGAASPPKGGNPDSNTLISDTTTVICLDDYHSLDRYGRKEKAVTALDPRANNFDLMYEQVKALKEGRSVEKPIYNHVTGLLDAPETIVPPKILVIEGLHPMYDERVRDLLDFSIYLDISDDVKFAWKIQRDMAERGHSLESIKASIAARKPDFDAFIDPQKQYADVVIQVLPTQLIPDDNEGKVLRVRMVMKEGVPFFEPVYLFDEGSTISWIPCGRKLTCSYPGIKFFYGPDTYYGNEVSVLEMDGQFDKLDELIYVESHLSNISTKFYGEITQQMLKHADFPGSNNGTGLFQTICGLKIRGVYERILANQKNESQVSAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIZ9</accession>
    <name>A0A8T0GIZ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G070700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000002">
        <property type="entry name" value="Myb family transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044787">
        <property type="entry name" value="HHO5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058673">
        <property type="entry name" value="HHO5-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31003">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31003:SF19">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR EFM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26575">
        <property type="entry name" value="HHO5_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="7">
        <location>
            <begin position="292"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="125"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="439"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="440"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="473"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="509" mass="55176" checksum="B941C9675EECCCE9" modified="2022-10-12" version="1">MGSPIDLTLGCSPQAPSNGYPSDVIPKVGSAYPGGYLESIRKAKEHLRSMEDERRKVDGFKRELPICIQLLEDAIQVSKEKLANGNDMPTLQLSCSSMDSVKERNDAMESRPTLEEFLPLKRRWDAAQQSEGSDGDKEGSLESPRGTKRPAWMTEPQLWIQNSTSTQVCHEKEKEPERFEQDHSCVTDSQLRLGSKEKSTGAFLPFLREHPDGAAAPLVSRPTPTMAHCGIGSSLSFGDLIASPNSSKAASEPEAGSIDAGLPTSDAQTGKDMGMLSNGSSGGGSSTKSNPSKRKARRCWSPELHRRFVSALHQLGGADIATPKQICELMKVDGLTNDEVKSHLQKYRLHTRRPSSSPQSATGAQSPQLVVLGGIWVPPKYTSSASQLSAGVYDSSTGHHSQPTQFYQSAVLPQDHYFACISNGPSGPSVEMHRQPIFEPQQAASQSQSSPQGSLQVTSQFSEATQGPNSTEVYHDDSGEEAKSDSTSWKNESYEDEELKKSSSDCTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJL3</accession>
    <name>A0A8T0GJL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">BZIP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_10G085500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJL3"/>
    <dbReference type="OrthoDB" id="664875at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.170:FF:000020">
        <property type="entry name" value="BZIP transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020983">
        <property type="entry name" value="Basic_leucine-zipper_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004827">
        <property type="entry name" value="bZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046347">
        <property type="entry name" value="bZIP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46408">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46408:SF10">
        <property type="entry name" value="BASIC LEUCINE ZIPPER 63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00170">
        <property type="entry name" value="bZIP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12498">
        <property type="entry name" value="bZIP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00338">
        <property type="entry name" value="BRLZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57959">
        <property type="entry name" value="Leucine zipper domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50217">
        <property type="entry name" value="BZIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00036">
        <property type="entry name" value="BZIP_BASIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BZIP" evidence="8">
        <location>
            <begin position="235"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="246"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0559190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="45987" checksum="AAE1EA9B1894B0C6" modified="2022-10-12" version="1">MDRISSVDDMMGTASFWTTESSGPKSTMNRSASEFAFQEFLKETLVAGGERAKSRFKAESEVGEEDQKPEVPMFASTEELRAMNNVVDSVAEDDEVAVIEGALNPLFSGMQDTGEKSYGEFNTSAAANGSGQDYEVFLKQKLEIACAAAALSRANGDGATIGLSTGAIAQPNFGGELSGVSTLPNRKQSSPVGIPALPPKPEVDAFGKFRPITSGSELSDDDEHDLLNQNLPRSELKRVKRMLSNRESARRSRRRKQAHLSELEMQVAQLRVENTTLMQRLQEVSHMHKEASVDNRILKADVEALRAKVKMAEDMVVRQGQQPMTNFIPDPSLSFMTPYMVNDMERPFMQQLRHSSMLRQDQQQSNNGSKMGRTPSMQRVASLEHLQKRIRNGGSCNAPAWGGWEMDRAAIVQGHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLJ4</accession>
    <name>A0A8T0GLJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G080900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7583" checksum="E01BDD8F4AA8E218" modified="2022-10-12" version="1">MPLQVRHHCTILLACYGSGAPDRGMMTFDEFTQPPKLVERGFIEKCKGRINHNIGTSQSPLILVTITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMS6</accession>
    <name>A0A8T0GMS6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G075600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="16"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="49551" checksum="1701522256888CE4" modified="2022-10-12" version="1">MAEEESEMVGGDGTAGIVWSELPKDVRLKVLSHLGIQDLCRMRCVCREWRDVIHHRDFRGMYDMANSSQEPRPVMCYLESSYPLRLEWTAYDYEGKLWKKMNSFPSLSHSCLTTLNARVQNFSSLNVGLYSVGGLLCLLRWHYLQVIETGRAPSPCRVISSWTVWNPYRNRWKKLLPPCKHKVSDIASSFVHVFVSDERTKAYKILMAHGVASHPNHSFHAGEQKLVTEIYDSRTGTWTDGAEHTLKAKLSYRRPFVRGVLCNGVIYFATERYETHQINRFSRPSVLLSYDINKDEWLEETLDSFLLLFEWDGRLMALNVDNAADGSTEQKFLEWDLVRRMWKDTCMSMPLKIGKAFRYDLEGFSIVASGNHLAVTGLTMDVTEFRIAVYKRAENYWRMPPTATFSDKLRPARVEGLVLHRPSLDWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQD5</accession>
    <name>A0A8T0GQD5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription factor TFIIIC triple barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G040000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQD5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000127">
        <property type="term" value="C:transcription factor TFIIIC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006383">
        <property type="term" value="P:transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042771">
        <property type="entry name" value="GTF3C6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019481">
        <property type="entry name" value="TFIIIC_triple_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21860:SF2">
        <property type="entry name" value="GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21860">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10419">
        <property type="entry name" value="TFIIIC_sub6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor TFIIIC triple barrel" evidence="2">
        <location>
            <begin position="81"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="288"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="404" mass="44220" checksum="1E8A1A6EAEF06100" modified="2022-10-12" version="1">MSFPRDVDYRYEGRIRDRDAGITRNIDHFMEELRREQEAIDKRTAEYEKRRNELRSQIDQTGNGAMSLDDTEVAEENDEEDWEEEYVVLDLDNVFHGAPIPNFAYTLSGLDTLNPILTLDNGLKLIGQYTETIGSVVVYSEKEKDVSEAQADTRQFSTPADPFAVHTVKKPLKRIRGVCKLERKLKFCAMPAPPNIGMFMQSTIVQTAMPAGGASRTNARPVESSIFQKTARPVEDSIFYGPTRLVPVEDSIFQEPAPTGNASLGSNTPSENARPVEDSILEEPAPTGNASLGSNIPSENARPVEDSIFEEPAPTENASLGSNIPSENARPVEDSIFEEPAPTENASLGSNIPSENARPVEDSILEEPAPTGNASLGNNTPSENARPGEDSIFESSIGSVDQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR89</accession>
    <name>A0A8T0GR89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flavin-containing monooxygenase</fullName>
            <ecNumber evidence="8">1.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G037800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>indole-3-pyruvate + NADPH + O2 + H(+) = (indol-3-yl)acetate + CO2 + NADP(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34331"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17640"/>
            <dbReference type="ChEBI" id="CHEBI:30854"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.168"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the FMO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103075">
        <property type="term" value="F:indole-3-pyruvate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004499">
        <property type="term" value="F:N,N-dimethylaniline monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000100">
        <property type="entry name" value="Flavin-containing monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050982">
        <property type="entry name" value="Auxin_biosynth/cation_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020946">
        <property type="entry name" value="Flavin_mOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539">
        <property type="entry name" value="FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43539:SF78">
        <property type="entry name" value="FLAVIN-CONTAINING MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00743">
        <property type="entry name" value="FMO-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0274">FAD</keyword>
    <keyword evidence="2 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="434" mass="47784" checksum="0B051A432B709A53" modified="2022-10-12" version="1">MPPHVMQSPSCGAEYWGKQTQDKVKYFDGVIIVGAGPSGLATAACLQAQGVRVLILEKAACIASLWQLKTYDRLHLHLPKQFCELPLFPFPADFPTYPARDQFVNYLQEYSSHFGLRPLFNHAVNQAEFDSRSGLWHVKTTAGCSVREFRARWLVVASGENAEPVVPVFKGVNEFEGKVFHSSAYRNGVAFEGKKVLVVGCGNTGMEIALDLANFGASPTLVVRSPTHILPREICGKSTFLVAMMLMKNLPVWLTDRLLVGYTYLTLGDTAKVGIPRPSEGPMLMKERTGKTPILDVGTFAAIKSGQVKVRPAVECLTPTGAQFEDGRREDFDAIILATGYRSNVPKWLKDDSKFFSEEGLPRQPFPHGWKGESGLYVAGLGRKGLLGASKDARSIALDIAAEISIADIPSLRLVPCQHEQHEQQQQQQRLLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT46</accession>
    <name>A0A8T0GT46_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G056300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="137"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="993" mass="112204" checksum="8AB66F3A3AE1883F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTK6</accession>
    <name>A0A8T0GTK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_9G028300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTK6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009585">
        <property type="term" value="P:red, far-red light phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16504">
        <property type="entry name" value="RING-HC_COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000090">
        <property type="entry name" value="E3 ubiquitin-protein ligase RFWD2 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042755">
        <property type="entry name" value="COP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44080">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44080:SF1">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE COP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-0607">Phytochrome signaling pathway</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="3 14" id="KW-0853">WD repeat</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="17">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="486"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="14">
        <location>
            <begin position="572"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="222"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="139"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="238"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00084091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0560988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="701" mass="78156" checksum="2167FF297D219C7C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVD8</accession>
    <name>A0A8T0GVD8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WASH1 WAHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G176500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WASH1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVD8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071203">
        <property type="term" value="C:WASH complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003779">
        <property type="term" value="F:actin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043014">
        <property type="term" value="F:alpha-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043015">
        <property type="term" value="F:gamma-tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034314">
        <property type="term" value="P:Arp2/3 complex-mediated actin nucleation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032456">
        <property type="term" value="P:endocytic recycling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042147">
        <property type="term" value="P:retrograde transport, endosome to Golgi"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028290">
        <property type="entry name" value="WASH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021854">
        <property type="entry name" value="WASH1_WAHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23331">
        <property type="entry name" value="CXYORF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23331:SF1">
        <property type="entry name" value="WASH COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11945">
        <property type="entry name" value="WASH_WAHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0009">Actin-binding</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WASH1 WAHD" evidence="4">
        <location>
            <begin position="14"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="22528" checksum="CF9D4D85C1FE0699" modified="2022-10-12" version="1">MAGVGEGRGKSDAQLCQSLLDLYDVADTVFNTILNRVKSEQEKLNNLTARIVEREAQVAAIAGTKEAITLFSTAKYLQVPTEQADFVPLFGGKQSEFPIATVSIDAGQHQDGEGGTLELFRFFSETNHEYWPRETQSAEGLGRFPKDTKSVADAMLFNSLELPYHLYRVVDNIAGADIVVGRRNPSTSLPHLLPHLKVSWLVIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYM5</accession>
    <name>A0A8T0GYM5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G138200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15796" checksum="122B83D79E99F8BA" modified="2022-10-12" version="1" fragment="single">MLHLRQFIKLKVKHRNPLKAWENAQWMYEWSKPKVGEGLCTWLVFIIHSEKVFSMRNPGAYRWSPLPQSIQDKLPALSVKMAKWSLGINEHKFFLGPYPPTQIPDAGTHPWHPEQTPEQGSINGDNEGGSSPIIISNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYR0</accession>
    <name>A0A8T0GYR0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G074200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="268"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="279" mass="32304" checksum="D1412D867BEE7601" modified="2022-10-12" version="1">MLDMSVMKYEEQNEDSKEKLRDALKARFEFLDHEMTDSSLDKMIKTWIRRNRERLKRVHGGKLKAPRKYSETQWDTLKRYWDTPISRQKSERMTETRKKRKEREVTPCVTDVAKELKTAMANPDTAEMEKKNSQRLSAMEKRLEDVLQSNMQLQAMLRTVLNTVSPDVVKDIRDIPPSESPGVEEQPDTEQKNNCTGAMNSTGLVNSECWWDNVCKSSDEERDVGAKGRERVSMNSTTQHLGQQQQSAHTRSQVLTEKHQSSERKGRTTCSLSSRTQSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZG7</accession>
    <name>A0A8T0GZG7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G037500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044800">
        <property type="entry name" value="LEC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140:SF74">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR LEC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="246"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="107"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="357"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0563514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="384" mass="42223" checksum="01653DD9D6AEFD68" modified="2022-10-12" version="1">MDEGSGKNGGERTSAEVWSALKPSRGRTVEGGHGNSDHMRGNGRELHGPSWEAPSSFSDENPLHAWGGPGGAACHGSPNSLALEAGAPRWNYRPSSEKHHCGARHEYTGMQPRPVAEHRQGWGGDQHHFHAGAAARPWSETKLDRMMAMYESQITRTVSNDHFAAIAALGHENLTLQLASEKLMDISLQRSGSDAGSKQEGEAQSLPKTALVGTSSDLKRKRLEIAICAETDQAECGWSHPLKLLVRKGLSVSDVGELGRIIIPKRFAESKFQQIDAKEGTLLEMEDYNGSKRWFFRFKYWVNNKSRMYVLENTGEFIKYHSLKEHDIFVVYEDSVKKLVVRGHKGTDLDSIPDVSPQGTNPGISTDNSTPTREQGPASTTVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZR5</accession>
    <name>A0A8T0GZR5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G168200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZR5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056712">
        <property type="entry name" value="DUF7810"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35736">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35736:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25102">
        <property type="entry name" value="DUF7810"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="772" mass="84595" checksum="B2D573CDB819B7F0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0E0</accession>
    <name>A0A8T0H0E0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G098000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0E0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9672" checksum="9FE671E9E64751C4" modified="2022-10-12" version="1">MIELGHFRSVREFSSGLSAFELCFFFHVFVYWGIEGRDSLVGFEDKGGVGCVKHRLFSEKEKEPWSIISLNTYVTMVTMIRTGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1P0</accession>
    <name>A0A8T0H1P0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G032100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1P0"/>
    <dbReference type="OrthoDB" id="9991235at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3210.10:FF:000017">
        <property type="entry name" value="Deoxynucleoside triphosphate triphosphohydrolase SAMHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.2760:FF:000001">
        <property type="entry name" value="Metal-dependent phosphohydrolase HD domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050135">
        <property type="entry name" value="dGTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF4">
        <property type="entry name" value="DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="67"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="464" mass="53961" checksum="2644C29103C97ABC" modified="2022-10-12" version="1">MVASVDDGFPREHRRKDNKLFHDNVHRNVYIDSLSMKFVDSEQFQRLRDVKQLGLCHYVYPGAMHSRFEHSLGVYHVAGEVMDYLKRSQGDELELEPADFRTVKLAGLLHDIGHGPFSHVFDNEFLPRALPNFKWSHEQMSADMVEYIADLHHIDIDGSDLKRVKALILAASKGSTVQVYGDKRFLFDIVANGRNGIDVDKFDYIERDTRACGLGRNFDYHRLVENMKVIDDEICFKAKEALTVYRLFQTRADLCRTVYTHAKVKALELMLVDALLLANDYLKLTSYIEGPSRFWKLDDTVLKTIETAEQPELQQAREVVLRMRRRQLYQFCNEYAVPKEHLEHFKDVTAKDIICSQTKPGVNLTEDDVLVHATRIDFTRGLENPVSTRVHFFQDFDSTEKFLIPQDKISHILPETFQDRIIRVYAKKPEHVEAVCEAFEEFQRKQFGYTSQIHGTPERKKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3J2</accession>
    <name>A0A8T0H3J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BAG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G182000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23767">
        <property type="entry name" value="IQCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040400">
        <property type="entry name" value="BAG5/6/7/8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003103">
        <property type="entry name" value="BAG_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33322">
        <property type="entry name" value="BAG DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33322:SF4">
        <property type="entry name" value="BAG DOMAIN CONTAINING PROTEIN, EXPRESSED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02179">
        <property type="entry name" value="BAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63491">
        <property type="entry name" value="BAG domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAG" evidence="2">
        <location>
            <begin position="568"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1489"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="425"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="840"/>
            <end position="853"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="857"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1170"/>
            <end position="1185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1512" mass="163249" checksum="14E3AA1DEC367A9B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4B8</accession>
    <name>A0A8T0H4B8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G176600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4B8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035833930" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5970" checksum="707E8F4637C9B506" modified="2022-10-12" version="1">MLISFNHVFVLSLLGPSLNSHWNDHNSCSIEEPNCNSRSKSIMIRDGKLASRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7Z9</accession>
    <name>A0A8T0H7Z9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDAN1-interacting nuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G056900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7Z9"/>
    <dbReference type="OrthoDB" id="1272at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029404">
        <property type="entry name" value="CDIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661:SF1">
        <property type="entry name" value="CDAN1-INTERACTING NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661">
        <property type="entry name" value="SIMILAR TO CDNA SEQUENCE BC052040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14811">
        <property type="entry name" value="TPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="33164" checksum="35DC6EC3B64AE845" modified="2022-10-12" version="1">MKAAVHVELRQAVLQDDKRALEAVKEKYPWVEFDTVVAIKSQEGSRQIRMQHHKFRTRQRIQEFIGRYTSGEDILEISRRYDIPPCFLMRILLEHMAGLQKHQVSVCMKDPSYLPDSSTLVKAQMVASRDISATVSRARLCADVFRCIDNDTVSSPAVETIRRVTGLEYEMLLYEKLRELGISYQSEDDLRAAGFSKTPDVKLDAPIGVRGRMVNWIDSKASFGDEHIHKAQGSDQFQSYVNRFGPGMVIYWFGYIDELNDNPDILLMDHFPDKSEVYCLTVLPVQARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H845</accession>
    <name>A0A8T0H845_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G133800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H845"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="20591" checksum="DB798248A3CC5BA1" modified="2022-10-12" version="1">MTERPSSSNAGEGQVVARVSVKDRLGPLPPQSASKRGRDRSVDRNHRRGRKFSNSAQGAEPNFQGGAKTGRVPVHERLGPLPPQAFKKNDLFQKRNRQQVWRHQGNFTQSNFKAAPASEEPEEQGTAALGDGENVENVKPPNVKYVKPPVPALPIVQPFNAEQHRQAWTWVRPATNTTAMEVDEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8A0</accession>
    <name>A0A8T0H8A0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G180500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8A0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="35"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="15267" checksum="11F7F2C592F61DBF" modified="2022-10-12" version="1">MRYVYQEVAKCGEHKRIVAMFETWPMIFFKVITKKAIKSLTLSGSDFTILDIPVAFTEEYTEVYGELSEVRLERAFGDKVWPVVMKKPGVGGAMNLLFLHGYDGWRKFFEENGVKEGDILVFQVIEKSRFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9V3</accession>
    <name>A0A8T0H9V3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G099200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005202">
        <property type="entry name" value="TF_GRAS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31636">
        <property type="entry name" value="OSJNBA0084A10.13 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03514">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50985">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="107"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="782" mass="86535" checksum="4950FF70E44D24A1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB63</accession>
    <name>A0A8T0HB63_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G189800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the thioredoxin family. Plant F-type subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB63"/>
    <dbReference type="OrthoDB" id="2121326at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd02947">
        <property type="entry name" value="TRX_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46115">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="73"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00038337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="21430" checksum="5285C34A9544AB0F" modified="2022-10-12" version="1">MATALAGETMAMAISSPGYIHVSLASSTSSASSLSMAGWSHRRTRSASMLVAVGLGSGKLGAGRRATGSSGASSLVCRSSVSPLSDANGNVAVFQSEEEFNTILNDAGDKLVVVDISTTTCGPCKMIFPKFVEMSLAYPDAVFLKINGDSSAESRALMRKWGVRAVPNFRFFKNGEQVHSHTGAKVDELKTRFAEHYGQSIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBY8</accession>
    <name>A0A8T0HBY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G239700</name>
        <name evidence="3" type="ORF">KC19_4G267200</name>
        <name evidence="2" type="ORF">KC19_6G080500</name>
    </gene>
    <organism evidence="2 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13864" checksum="1B305B9F6EEE6F0A" modified="2022-10-12" version="1">MDSQELDTMPVMSSQPTNSRRRSRDEEPPVPRRRRRIPSNRSLVIVFEVEPAFNGLPEGVFAGQFHNEDTEVHAWSEVEGVGHYRWLQGPMNHLPREQQLEFIADVMRQIFIFLRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDA5</accession>
    <name>A0A8T0HDA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G107500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDA5"/>
    <dbReference type="OrthoDB" id="6049624at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.600:FF:000005">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="11">
        <location>
            <begin position="49"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="12">
        <location>
            <begin position="248"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0567062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="451" mass="49793" checksum="D7C7E7450B3CBFDE" modified="2022-10-12" version="1">MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPCDKTVSGGDDAFNTFFSETGAGKHVPRAVFLDLEPTVIDEVRTGTYRSLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFHAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSNAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDLCRRSLDIERPTYTNLNRLVTQVVSSLTASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPVVSAEKAYHEQLSVAEITNSAFEPSSMMAKCDPRHGKYMACCMMYRGDVVPKDVNASVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNTTSVAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAESGEGECEDEGEEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE85</accession>
    <name>A0A8T0HE85_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G122600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10922" checksum="8B8903A1E73ACDA2" modified="2022-10-12" version="1">MWGFRDHGAAAATPLSPSLSLSPLSHTAQASRPKPVTTPKVDIIYSAHIFCSFKSTYSGDGYTFAISREENSVTLGGKGSKTVSVKIFCHWCTLEWLGSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEI0</accession>
    <name>A0A8T0HEI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G131300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEI0"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000175">
        <property type="entry name" value="Hydrolase-like protein family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF11">
        <property type="entry name" value="LIPASE YOR059C ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="1">
        <location>
            <begin position="58"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="427" mass="47448" checksum="B32E6141F632F044" modified="2022-10-12" version="1">MRVDLSISNTDESCNCGIATDYGGKREGHVGNMKDRKFLSIMQQPSEKQEQSESDDDSEPDHLLILVHGILAKPGDWDYVKRKLMKRLGSKFLIHASAVNSFLNTLGGIDHAGRRLASEIEQIAEKVPSLKRISIVAHSLGGLFARYAVTMMYTPKDDLTEDMYILEDLERRGEEHPVFRRRREPKIAGLEAVNFITLASPHLGVRGKKQLPFLFGVPVLEKLAAPIAPFVVGRTGKQLFLTDGKASDPPLLLRMASDCPEGLFISALRAFKSRVVYANVSYDHLVGWRTSSIRRECELSKPPRASIDGRYKHVVNVSYSPAVDSDAPSFQQESAQGKAAAQVSPSSKKAAAYHDMLEEEMVRGLQQVSWRKVDVSFHAALWPFNHMSHNAGIVMDKRFHFEGTGVVAHLADTLAQQEQNVFIAASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFW9</accession>
    <name>A0A8T0HFW9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G178700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFW9"/>
    <dbReference type="OrthoDB" id="410307at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051252">
        <property type="term" value="P:regulation of RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd22464">
        <property type="entry name" value="KH-I_AtC3H36_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF18">
        <property type="entry name" value="PROTEIN TIS11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="110"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="314"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="139"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="152"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0570661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="36729" checksum="C08AB317551013B6" modified="2022-10-12" version="1">MDPYGPPRKRPRPESGPLNGSNGANGGHGGVDDYNKDGSSGNRTKPCTKFFSTSGCPYGEGCHFLHFVPGGMPSMGGLAPLANIGSMGGAGARKVVGGVGPDDQGANLGGFKTRLCNRFDTPEGCRFSDKCHFAHGEKELRKSSTNFNAPSIERDTYPRQDYSRDQGPPSASYRGGAGTGLYGSNSGGRFGSGGPGREREVGGQGGRFGSYREPTPPGMAAANSFGASSTAKISIEASLAGAIIGKGGINAKQICRITGAKLSIKEHETDPGLRNVEMEGSFEQIKQASQMVRQVLMQRDNVPARPPAGAVSHNFKTKLCENFAKGTCTFGDRCHFAHGPEDMRDPFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG49</accession>
    <name>A0A8T0HG49_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">V-type proton ATPase subunit S1/VOA1 transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G127500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046756">
        <property type="entry name" value="VAS1/VOA1_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35285">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35285:SF1">
        <property type="entry name" value="2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATE CYTIDYLYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20520">
        <property type="entry name" value="Ac45-VOA1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035905401" description="V-type proton ATPase subunit S1/VOA1 transmembrane domain-containing protein" evidence="6">
        <location>
            <begin position="29"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="V-type proton ATPase subunit S1/VOA1 transmembrane" evidence="7">
        <location>
            <begin position="288"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="34913" checksum="7E297830C704ED2F" modified="2022-10-12" version="1">MARRCRAMESALLAFLLLGVLSVHVVAAHALPDGHSTTVTPAFVWSDLRCFGEQDRSFNYESQSSDSLVDTVFHAFGSCEVTQDVSQGKANPEMVVAFIGRELRSEDISRSQFSDVLMTLQESIAGTKYSLSFPYVTVASNRASVGESLISNVQKKLGAGSKIGQVAVSGSCSVGRHDVKRLTGVPDIEAYIAGRKTSRAQEETDVLLICYSPALDWNLASVYTSEGKVLEEVLSALKSSGTSNFVMYTSDPLASTQKHYGILERHLLDGTGNATTDCDALCRSRAVILEGIFVAITLITILVSGICCMKAVKSPSRFEVSKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGY6</accession>
    <name>A0A8T0HGY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G178500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGY6"/>
    <dbReference type="OrthoDB" id="442921at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10562">
        <property type="entry name" value="SMALL UBIQUITIN-RELATED MODIFIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="19306" checksum="3D96E38C1BD9EC18" modified="2022-10-12" version="1">MDDHVLRDLILERIDAALKRVCDPDKVVDCLDAALQQACNPEKPVKEGPPLTEGSGDSEEPADNDVNKAIAPEAKSEVQLEVKPAEEQPKLDGSAQHINLVVREVTGKHTIHFRMKTNTSFRKLMNAYCDKMSVDPSTIAFIFDGRRLQTQHTPAELKMEEGDMIDAFVHLMGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH61</accession>
    <name>A0A8T0HH61_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G020500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8548" checksum="E19BA3E8294B5738" modified="2022-10-12" version="1">MAARRLGNTTAPVDLPVARHAHGFEQTSWRAQLGVQGKDSTFLSRWRAAQVTPVCNVCASVNELWHQSCKEWLVGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIP0</accession>
    <name>A0A8T0HIP0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G180400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000034">
        <property type="entry name" value="Kinase suppressor of Ras 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF271">
        <property type="entry name" value="ATMRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="84"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0570684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="43757" checksum="869EC42C1CEAEE80" modified="2022-10-12" version="1">MEGTLENAPSGETENPEMKVSKVEDNAVKLEKKKSMVRADLVNLAEVERHLSKAYSRSAAEPSAETVSEPTGPIEEWEINPREINLKSIIARGTFGTVHKGVYKGQDVAVKLLEWGEEDTMTKSEVQYYRNQFRQEVAVWHKLDHPNVTKFIGASMGNSNLRIPSAVDGDDDGFHHVPNNACCVVVEYLAGGTLKDYLIRNRRKKLSYKVVVELALDVARGLAYLHSQKIAHRDVKTENMLLDKTRRVKIADFGVARVEASNPKDMTGDTGTPGYMAPEILDGKPYNKKCDVYSFGICLWEVYCCDMPYLTLSFADMTSAVVHQNLRPEMPKCCPNALADVMRKCWDANPEKRPQMADVVGMLEALDTSKGGGMIPDGAQPRGCFCFGKYRGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIV0</accession>
    <name>A0A8T0HIV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G131000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="121"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="121"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16606" checksum="791DC933457FF8AE" modified="2022-10-12" version="1">MKFSPRVSSSRRKSRKAHFSAPSSERRILMSAALSSDLKNKYNVRSVPVRKDDEVMVVRGTYKGREGKVVQVYRRKWVIHVERITREKVNGATVNVGIDTSKVVITKLKLDKDRKALLERKGKGRAAEKGKGKFTDADVAPPLQEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJR7</accession>
    <name>A0A8T0HJR7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G206700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="275" mass="29942" checksum="56B863192BDBF5CE" modified="2022-10-12" version="1">MALQTASVAKLSSLCRTLLPLSSCIQHGNTMGVALKGSFLTQGSECDILSSSSRSACASEARRAWRPVMVRATSSQRWTLDDVERISKGKASKAKTGSRKVPHRLQAGERTAYDLAKKKGYLVQRAVSRKYPLVNTYRNFCDASCRLCIFIQQGPTGADTVVIDLTPLRLSGDALVKIREQVAEVVQSTLQSFSPDGQQADGYSSAEEDSEAEKSGEPSSESSKEDEEEEDANADEESLSILRIETGRSEAKAICQAAWDFWQAHTKTGKVPLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJZ2</accession>
    <name>A0A8T0HJZ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">acid phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G212700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16343">
        <property type="entry name" value="LMWPTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2300:FF:000113">
        <property type="entry name" value="Low molecular weight protein-tyrosine-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052995">
        <property type="entry name" value="LMW-PTP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47439:SF1">
        <property type="entry name" value="ACID PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47439">
        <property type="entry name" value="LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="Phosphotyrosine protein phosphatases I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphotyrosine protein phosphatase I" evidence="6">
        <location>
            <begin position="88"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR617867-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="262" mass="28102" checksum="AEC249FF7F91DF1E" modified="2022-10-12" version="1">MASVFSAPSSLTGSRAASSRVPCRSVFLPALRVSESVSVVCGSGEFRGGVKAAVRSVGREALGCGSRVTMAASAEVSSSVAEAERRPFGVLFVCLGNICRSPTAEAVFRDVVEKRKLDSLFNIDSAGTIDYHEGNPADPRMKAAALKRGVKLTSISRPIRSSDFEEFDLILAMDKSNRADILTAYESWNRRAPLPAGSKEKVKLMCSYCTKHNVDEVPDPYYGGPAGFEKVLDLLEDACEGLLASIQELQVKDGKVDVKTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK48</accession>
    <name>A0A8T0HK48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mur ligase central domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G217500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008841">
        <property type="term" value="F:dihydrofolate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="entry name" value="Mur ligase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="entry name" value="Mur-like, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136:SF0">
        <property type="entry name" value="DIHYDROFOLATE SYNTHETASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="FOLYLPOLYGLUTAMATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="MurD-like peptide ligases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="MurD-like peptide ligases, peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur ligase central" evidence="8">
        <location>
            <begin position="144"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Mur ligase C-terminal" evidence="7">
        <location>
            <begin position="420"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0571181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="633" mass="67203" checksum="9ABA52F3C3C6F6F3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKS2</accession>
    <name>A0A8T0HKS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G266500</name>
        <name evidence="1" type="ORF">KC19_VG006600</name>
        <name evidence="2" type="ORF">KC19_VG101300</name>
        <name evidence="3" type="ORF">KC19_VG164100</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16895" checksum="B157FF1C657055E9" modified="2022-10-12" version="1">MDPGWQTKVVFGKDIVRCTISLPSVTFRYHVGRSVLYSNFKYGRERLAQDGVTWELIDQVREEDMVVLPCFFQGLPVARFEVGRGWPLSHIRREVAITLGDVAPEEFRFVLKRVGYPDVKVNRRHEGSNTVSQVLPPWTFEIVALTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLV0</accession>
    <name>A0A8T0HLV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG030700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044823">
        <property type="entry name" value="ASIL1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31307:SF63">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31307">
        <property type="entry name" value="TRIHELIX TRANSCRIPTION FACTOR ASIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="60"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0571648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="31873" checksum="E4C2237ACD005D46" modified="2022-10-12" version="1">MALHGLPGILGLFRDGEGGASSTSIVVHTSTPPPPSQVLAPKRVPTKKRRGANEPVEGQAWSSGAIQLLLDLYKEKYLAIGMGNMKKGYWVAMCEGIRVKFPRESLRTWEQTKSKWQKMRSQYYKEKAELGTGTQASAWHWYVRMDDILAGTAKADGVPQGMDMGEDIGTGANPQELDDDNAPGAEPTSPATQVPAFGEHPRPPTTSCASKEVGGAPNKRLKTATQAATEGATIIAAALGKFAEASSKIEVMKMEASKEIAMKMIELDDRNAERQLQIAQLFAGAMRQGNGSGPSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMW4</accession>
    <name>A0A8T0HMW4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG058400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8618" checksum="047A08A8610CCD2B" modified="2022-10-12" version="1">MANNIKQVAADECTRKKGFTHKLGFKGVQGLVRVFMDEFDRPPTEEEVVFEKQNGIHVAVDKVQNRSIGGKMQEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN40</accession>
    <name>A0A8T0HN40_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG083700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16562" checksum="E72CEE5146C0A1E4" modified="2022-10-12" version="1">MAVPIADPYLHLSPTSSLVCADLFALRAVHSGPRAMLRLRCPMADFSFLLLRTPGSPLVTAFNEGSLQRTRAACYVWRGRPPCPFCTSILRLCCTLPGTVTFGTRPSSSISILASPLTHRMQFCKCSFLVSGLANFSHGYTIVDQPQLYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQJ4</accession>
    <name>A0A8T0HQJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG146200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="595"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="758" mass="84904" checksum="B9DD90E3B1D38904" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQK9</accession>
    <name>A0A8T0HQK9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG157700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQK9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8439" checksum="A10FB99E8B9C0206" modified="2022-10-12" version="1">MRYFLCLFVFSAHRSRTNSTWKPLGREESVFSALPSHVAISSGPPSPRHSPSLMIKTAGTTMVECAQTNSQSYSSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR64</accession>
    <name>A0A8T0HR64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG159700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="13983" checksum="6FC52B45EA8C3A7B" modified="2022-10-12" version="1">MRLDVIDYSLLAIAPDERNIPSAIRYVRFDTFMECHTELWLSRVRFLATKEGSLHSPYFGKSSQRRGSNAGLHQHKDLRRLLMDSDNMLLYLESHVIGYQRVSDKVRNNLMSYSDLMSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR95</accession>
    <name>A0A8T0HR95_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuBisCO large subunit-binding protein subunit beta, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG167900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.7.10:FF:000001">
        <property type="entry name" value="60 kDa chaperonin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="entry name" value="GroEL-like equatorial domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="entry name" value="TCP-1-like chaperonin intermediate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000592">
        <property type="entry name" value="PRK00013.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009487">
        <property type="entry name" value="PRK12849.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009488">
        <property type="entry name" value="PRK12850.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009489">
        <property type="entry name" value="PRK12851.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45633">
        <property type="entry name" value="60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="GroEL apical domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="GroEL equatorial domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="GroEL-intermediate domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0573317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="601" mass="63436" checksum="535BD94683830FF8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSD6</accession>
    <name>A0A8T0HSD6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG212500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15267" checksum="F9F7097070CA06A6" modified="2022-10-12" version="1">MDFSNYARGCRDLSPTFSTSDDASSSFIDYADSNFCSVQKESHHSIVAEHQQRHTMTSPYSRDSTLFPPRRLEDSDMGPGFNHSQLASQVSSFLKIILELNVYNCATQHRRVYAAITYSTMFTSHTVTVESVRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU23</accession>
    <name>A0A8T0HU23_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG255600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035877869" evidence="1">
        <location>
            <begin position="16"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5785" checksum="F9487AC422066A78" modified="2022-10-12" version="1">MFLSFLTRLLSLVLGHDFVLPFLETVVLANASFHALVPISSFPISCFTDFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUH5</accession>
    <name>A0A8T0HUH5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG283700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="321" mass="36837" checksum="C74681404E41D252" modified="2022-10-12" version="1" fragment="single">ILSPFCEECGCTFERDNAKFCRECRTPRGIRPDGTEENRQLVVQTVEGPAEEVIAGDLRGPPARQAVPGHRTRKAPTYNMIFDPPSVQNRAKNKLYGRKCLREDYAIQHKCYNNNHRTTHKWIEEAQSSGLLPQGEFTLEDPLVRGALKKIIDEKHDELMDINFGSGKKYSWKQTDAYKKIKKYLKYKRWRKRNLEKAQGGSTSGNSRANPSMSQPNDLHEFGESVDRNLEDEESHGDEEVDGQDDVTFVMRNLESENVHDMYGMLTTFMMGQNEIATRAKRRPPFPPNSRTYTNEDKIYLVANFFREQGAQQCAMDTASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV70</accession>
    <name>A0A8T0HV70_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG307000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="268"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="396" mass="44021" checksum="51EC4062168CFC8B" modified="2022-10-12" version="1">MHHRHDLQCRFKLPIHSSSFRVKQQFPSPEPQLTPQLEPSDLRIANSQLQESPQLQAFYTPPSLIRQPILGTCQQLSSPPRTTNKRRIKIKKIKITATPLGLHRPLYLKPTATSSFQTNLCRASHHELRSSPSSSLFTDLTSLQHQQKSSNRMHLPLTLNSHQHLGYRSKQLDLTIATALLFVYTLDSSPNNCNHMHRATALCTPNTLEFRDAATISSNKCRSLPPLLPSAEPSTSKTMQPPTTFFRPIITFFPEPLSVAPYKINSRRPSIKQSPSCSRNSAGTSNLQENTAVSRAQSTEQEGTTHQPAQPRSNSSKTNPTPLTTTTCNLLIAAFFEIRLVQASPTTPPSARTRLNCRHQNSPAPHQQILPSARPNTNTANHLDQSQVAPTAVSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV96</accession>
    <name>A0A8T0HV96_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG303500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="10833" checksum="42CBDA73F340D61E" modified="2022-10-12" version="1">MIGPDENPLGKTRALKRSKTDGTAQDSSLVGNLSRDSSGVQEGEESSGKGKRKAASKKTSSKKGTSGELLMSPKNVDTPEDILSPLRASKRDPRAKKHKGGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXM5</accession>
    <name>A0A8T0HXM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_VG328200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="569"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="602"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="672"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="714"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="797"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1261"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1347"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1374"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1402"/>
            <end position="1422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1434"/>
            <end position="1454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1487"/>
            <end position="1510"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="201"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="915"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="840"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="854"/>
            <end position="864"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0575223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1518" mass="170671" checksum="079E06351FC88400" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXZ7</accession>
    <name>A0A8T0HXZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G049000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8079" checksum="8FAA35E337AE8E3A" modified="2022-10-12" version="1" fragment="single">MRIQWRREGVGDGGGDLSLGFRFNSRGELVVHVESIRCQNFLLLAKFLPAFPPIVRSASASRQQSSRTIDSCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I083</accession>
    <name>A0A8T0I083_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ubiquitin carboxyl-terminal hydrolase 26</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Deubiquitinating enzyme 26</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Ubiquitin thioesterase 26</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">Ubiquitin-specific-processing protease 26</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_5G043600</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Deubiquitinates H2BK143ub1 of histone H2B.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 22">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I083"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02668">
        <property type="entry name" value="Peptidase_C19L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01795">
        <property type="entry name" value="Ubl_USP48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2230.10:FF:000005">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000049">
        <property type="entry name" value="ubiquitin carboxyl-terminal hydrolase 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2230.10">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035927">
        <property type="entry name" value="DUSP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033841">
        <property type="entry name" value="Pep_USP48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006615">
        <property type="entry name" value="Pept_C19_DUSP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044743">
        <property type="entry name" value="Ubl_USP48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF722">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06337">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00695">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143791">
        <property type="entry name" value="DUSP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51283">
        <property type="entry name" value="DUSP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="18">
        <location>
            <begin position="106"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="19">
        <location>
            <begin position="518"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="19">
        <location>
            <begin position="626"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="domain" description="DUSP" evidence="19">
        <location>
            <begin position="756"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="17">
        <location>
            <begin position="1011"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="399"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="980"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1151"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="1167"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="1223"/>
            <end position="1232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00071636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00075174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00078771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00082179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0575958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1232" mass="137237" checksum="39AF31C22CF7FC80" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1G8</accession>
    <name>A0A8T0I1G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Thioredoxin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G146000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR017199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16583" checksum="8394B22E57AAF758" modified="2022-10-12" version="1">MSYLPRHLHNAFHVDQVIQNEEERVTIIRFGCDSDVACMEMDEVLVKVAEKIKKFAVIYLVDIKEVPDFNVMYELYDPCTVMFFFRNKHIMVDLGTGNNNKINWALKDKEEFISIVETVYKGAKKGRGLVVSPKDYSTKFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3B4</accession>
    <name>A0A8T0I3B4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G144700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the small GTPase superfamily. Rab family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3B4"/>
    <dbReference type="OrthoDB" id="9989112at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01867">
        <property type="entry name" value="Rab8_Rab10_Rab13_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000308">
        <property type="entry name" value="ras-related protein RABE1c-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050305">
        <property type="entry name" value="Small_GTPase_Rab"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47980">
        <property type="entry name" value="LD44762P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00177">
        <property type="entry name" value="ARF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00176">
        <property type="entry name" value="RAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51421">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51420">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0636">Prenylation</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="182"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0577281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="216" mass="23870" checksum="04190E5A40654948" modified="2022-10-12" version="1">MAAGGSRARADYDYLIKLLLIGDSGVGKSCLLLRFSDDSFTTSFITTIGIDFKIRTIELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWIRNIEQHASDNVNKILVGNKADMDESKRAVPFAKGQALADEFGIKFFETSAKTNMNVEDVFFTVARDIKQRLAETDSKPEAAKNAKPDVKLSAGSAQQKPASGSCCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6J1</accession>
    <name>A0A8T0I6J1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G044700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6J1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13167" checksum="949878BE139CA98D" modified="2022-10-12" version="1">MEYVPSLRPLCAEFIFLFFLLSSSVFLLFTSTLITLYLYLYICVLHKREYLTSAGLYIFSALKHHDIVVRLFAAIAGSHTSGLICDRFSLVYVVSAVCAEFTSFPCAASHKTWYSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6W7</accession>
    <name>A0A8T0I6W7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G097400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6W7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="592" mass="65503" checksum="423EEEC03B36EE7F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I739</accession>
    <name>A0A8T0I739_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G055400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I739"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13163" checksum="57F337784378F29E" modified="2022-10-12" version="1">MASTHNYKKLTITCHQFSPYSDNRRSLLKLWDDQILMSANNSDSKFHRAHGFRNLKNSPPPTTPPPPQSTAHSQSPQLSTGLSQIGRQNHPGERHHTNIPWNQTEFPSYGGARCATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8V7</accession>
    <name>A0A8T0I8V7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G101600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8V7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24230" checksum="64BBAE7B4F2781C6" modified="2022-10-12" version="1">MDPPLLVLNSNNLADIADALIAELDTRFPANHVMDSLGIVFPQYWLQENVDSSFSAHLSILKDFFGTPKPCVNVEGDGDWVTQLLSSADLDSQMAMFKMAMKSNSKGVLTPPFTVNPMTKLWQILGSNALLVHAFIEYFKVARMAMTIVLGSVEDERAFSTVGFIKGKLRNKLGEHLPLCVQMFTQKFYTLKNFPYTEAVQAWRANKHRYCMNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9K4</accession>
    <name>A0A8T0I9K4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phenylalanine ammonia-lyase</fullName>
            <ecNumber evidence="8">4.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G112400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-phenylalanine = (E)-cinnamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21384"/>
            <dbReference type="ChEBI" id="CHEBI:15669"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="EC" id="4.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Phenylpropanoid metabolism; trans-cinnamate biosynthesis; trans-cinnamate from L-phenylalanine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.24" evidence="8"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9K4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045548">
        <property type="term" value="F:phenylalanine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009698">
        <property type="term" value="P:phenylpropanoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.275.10:FF:000009">
        <property type="entry name" value="Phenylalanine ammonia-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.200.10">
        <property type="entry name" value="Fumarase/aspartase (Central domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="entry name" value="Fumarase/aspartase (N-terminal domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.20">
        <property type="entry name" value="Phenylalanine ammonia-lyase 1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005922">
        <property type="entry name" value="Phe_NH3-lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023144">
        <property type="entry name" value="Phe_NH3-lyase_shielding_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01226">
        <property type="entry name" value="phe_am_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="HISTIDINE AMMONIA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="L-aspartase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0587">Phenylpropanoid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0579639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="724" mass="78986" checksum="EFC1B4941F42DD2D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBK9</accession>
    <name>A0A8T0IBK9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G226200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBK9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="13992" checksum="BC564E4E4CD3CF82" modified="2022-10-12" version="1">MVFICSQQKWPLRPSREDAGAAPGRRRSAGGVFSFGGAPRILEIRATWAGGEPPQLVSGTWVSAADNQGGEIVAIRGAGDWESIRGAGNVEVVRFPGACSGSRFRGEFFPPLGGLFCICRVQGLRIWILGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBV2</accession>
    <name>A0A8T0IBV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G132700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBV2"/>
    <dbReference type="OrthoDB" id="269518at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd23797">
        <property type="entry name" value="UBCc_UBE2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000024">
        <property type="entry name" value="Ubiquitin-conjugating enzyme 5, E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24068">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="9">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="6">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0579898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="21375" checksum="DC64530228918540" modified="2022-10-12" version="1">MSSPSKRREMDVMKLMMSDYKVEMVNDGMSEFYVEFHGPRDSPYQEGTWKIRVELPEAYPYKSPSIGFVNRIFHPNVDEMSGSVCLDVINQTWSPMFDLINVFEVFLPQLLLYPNPTDPLNGEAAALMMRDREHYEQKVKEYCERYAKLEDIGRRAEEDTSDGEVSEDEEYMSSDEEMAGHADP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC12</accession>
    <name>A0A8T0IC12_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G239500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11375" checksum="70AC40B1F9C5DD45" modified="2022-10-12" version="1">MVKRAAGDHNLTQVELMGHSGNFQLMVLCKEHEATTPSQFLGKSSSPCFHCSNFLARIQKLLHQEPVTPLFGNIKFAWISQNVEVLLTQGAGMYVWASMVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFA2</accession>
    <name>A0A8T0IFA2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G271800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8739" checksum="C38D4564709091F3" modified="2022-10-12" version="1">MTQYHPAHRGPRRITTQPHGVWTRHELHRGPPRNNKHVGHMHAVPRGTTLTAGSTPSPQHPPGRSSPSHRCQTQSPASP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFQ1</accession>
    <name>A0A8T0IFQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G004100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="200" mass="23031" checksum="7D777B59629B1FEC" modified="2022-10-12" version="1">MFDCSRDADDSTMGDEIWHLSCMVHLDMVNSVRGNLTRYCLSSHGPMTPVSVSPELHWFLNPLWDIGGLHSEKFHSPLFLNEYRVLLSQVHLYVMFISSFFARTKWLPCDSGHSRFLPMEIFFKKSKYLTPSLSGLSWNIFVFRYCTAGCSRTFVCPAAPNSLIKLMKIISIKNFLKSILSFSSSIHRVLHDYRCHHISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG90</accession>
    <name>A0A8T0IG90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G257100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. Lipase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000065">
        <property type="entry name" value="Phospholipase A1-II 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403:SF54">
        <property type="entry name" value="PHOSPHOLIPASE A(1) DAD1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31403">
        <property type="entry name" value="PHOSPHOLIPASE A1-IBETA2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="10">
        <location>
            <begin position="226"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="347"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0581503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="550" mass="62042" checksum="65FCA0166294DD25" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHD0</accession>
    <name>A0A8T0IHD0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G049500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17347">
        <property type="entry name" value="MFS_SLC15A1_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="299"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="456"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="59383" checksum="43951352446D6B50" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHL5</accession>
    <name>A0A8T0IHL5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Histone deacetylase interacting domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G057200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000122">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000001">
        <property type="entry name" value="Paired amphipathic helix protein Sin3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000002">
        <property type="entry name" value="Paired amphipathic helix protein SIN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1160.11:FF:000003">
        <property type="entry name" value="Paired amphipathic helix SIN3-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1160.11">
        <property type="entry name" value="Paired amphipathic helix"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013194">
        <property type="entry name" value="HDAC_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003822">
        <property type="entry name" value="PAH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036600">
        <property type="entry name" value="PAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039774">
        <property type="entry name" value="Sin3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031693">
        <property type="entry name" value="Sin3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346:SF0">
        <property type="entry name" value="SIN3A, ISOFORM G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12346">
        <property type="entry name" value="SIN3B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02671">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08295">
        <property type="entry name" value="Sin3_corepress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16879">
        <property type="entry name" value="Sin3a_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00761">
        <property type="entry name" value="HDAC_interact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47762">
        <property type="entry name" value="PAH2 domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51477">
        <property type="entry name" value="PAH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Histone deacetylase interacting" evidence="9">
        <location>
            <begin position="512"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="198"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="792"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="867"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="198"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="236"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="436"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="800"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="831"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="873"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="891"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1026"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1047"/>
            <end position="1056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="1059"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0582409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1410" mass="156400" checksum="B63098F25547FFBB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIH7</accession>
    <name>A0A8T0IIH7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G087500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000059">
        <property type="entry name" value="Putative acetyltransferase NSI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045039">
        <property type="entry name" value="NSI-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43626:SF4">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="161"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="308" mass="33866" checksum="A2464DCA5BF51550" modified="2022-10-12" version="1">MSMSTSMASLTTTLTPWSHRDPNPLAVSSSIAPSVILPLGDIARLTPRRGMVLQAQARIIGDGSVHGITGLEVCCFGAKKSVLSSSSRFQRHDSITSVQLERRDIQARSLWDSIRSGFGLNTPTAVVDSTEVEYKDDVELEDEGEVVLVEKVHDDGTIEKIVFASGVEVDVYELEILCDKVGWPKRPPSKVAAALRNSYMVASLHLLKQVQTTDGESPVLEKRELIGMARATSDHAFNATIWDVLVDPLYQGQGLGKALVEQMIRALLRRDIGNITLFADAQVVDFYKGLGFEADPDGIKGMFWYPRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIX6</accession>
    <name>A0A8T0IIX6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G083400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1172" mass="131761" checksum="B9AD4A4C0CA7C057" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJU6</accession>
    <name>A0A8T0IJU6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anaphase-promoting complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G125400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000211">
        <property type="entry name" value="Anaphase-promoting complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048971">
        <property type="entry name" value="Apc1_3rd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046794">
        <property type="entry name" value="Apc1_MidN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049255">
        <property type="entry name" value="Apc1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12859">
        <property type="entry name" value="ANAPC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21282">
        <property type="entry name" value="APC1_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20518">
        <property type="entry name" value="Apc1_MidN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0498">Mitosis</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="12">
        <location>
            <begin position="60"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 N-terminal" evidence="12">
        <location>
            <begin position="296"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="14">
        <location>
            <begin position="538"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 middle" evidence="14">
        <location>
            <begin position="761"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 beta-sandwich" evidence="15">
        <location>
            <begin position="1521"/>
            <end position="1584"/>
        </location>
    </feature>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="13">
        <location>
            <begin position="1653"/>
            <end position="1845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="867"/>
            <end position="890"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF12859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF21282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0583305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1909" mass="208648" checksum="9F646C40526BFC78" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKV5</accession>
    <name>A0A8T0IKV5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G168000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770599" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7498" checksum="03580126A3564094" modified="2022-10-12" version="1">MKVSKNGISCACYLLFVVQSITCFVVNFAEIPSDQNHPNRDKPVVRAKRRAELTCHKSGATVPTGYPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IML7</accession>
    <name>A0A8T0IML7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH La-type RNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G193500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IML7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000339">
        <property type="term" value="F:RNA cap binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048255">
        <property type="term" value="P:mRNA stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07323">
        <property type="entry name" value="LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000131">
        <property type="entry name" value="la-related protein 1B isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006607">
        <property type="entry name" value="DM15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045180">
        <property type="entry name" value="La_dom_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006630">
        <property type="entry name" value="La_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792:SF132">
        <property type="entry name" value="LA-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22792">
        <property type="entry name" value="LUPUS LA PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05383">
        <property type="entry name" value="La"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21071">
        <property type="entry name" value="LARP1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00684">
        <property type="entry name" value="DM15"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00715">
        <property type="entry name" value="LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50961">
        <property type="entry name" value="HTH_LA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HTH La-type RNA-binding" evidence="4">
        <location>
            <begin position="424"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="529"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="653"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="749"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="843"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1141"/>
            <end position="1165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="208"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="663"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="689"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="796"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1147"/>
            <end position="1156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1165" mass="123588" checksum="67E2A7DF01076FD0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IND9</accession>
    <name>A0A8T0IND9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hexosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G230300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 4">Glycan metabolism; pectin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IND9"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047262">
        <property type="term" value="F:polygalacturonate 4-alpha-galacturonosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06429">
        <property type="entry name" value="GT8_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029993">
        <property type="entry name" value="GAUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32116:SF27">
        <property type="entry name" value="GALACTURONOSYLTRANSFERASE 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32116">
        <property type="entry name" value="GALACTURONOSYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="60402" checksum="6B54E129B43A0C3C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISN1</accession>
    <name>A0A8T0ISN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G112400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6893" checksum="EC888D514CBCBB25" modified="2022-10-12" version="1">MTTALVVVPLGDVLRWLPWKFIATAGGAELCRCFDRNTRCFGPSPMRVTTRTGMVMMMDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISU1</accession>
    <name>A0A8T0ISU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G071000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="85"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="587" mass="66827" checksum="C3D1AAA79DF9E208" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU89</accession>
    <name>A0A8T0IU89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G099100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015629">
        <property type="term" value="C:actin cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051015">
        <property type="term" value="F:actin filament binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007010">
        <property type="term" value="P:cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030032">
        <property type="term" value="P:lamellipodium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.950.10">
        <property type="entry name" value="Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051618">
        <property type="entry name" value="Actin-binding_LIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003128">
        <property type="entry name" value="Villin_headpiece"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036886">
        <property type="entry name" value="Villin_headpiece_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213">
        <property type="entry name" value="ACTIN-BINDING LIM PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24213:SF9">
        <property type="entry name" value="UNCOORDINATED 115A, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02209">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00153">
        <property type="entry name" value="VHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47050">
        <property type="entry name" value="VHP, Villin headpiece domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51089">
        <property type="entry name" value="HP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HP" evidence="2">
        <location>
            <begin position="198"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="263" mass="28198" checksum="AE6980DEA24E55AD" modified="2022-10-12" version="1">MDPVVDNIEVANSEVANKEVVNSEEANKEVVNSEVANSEEAKSEVANTEEAKSEVANTEVANSEEANSEEAKSEVAISEVANSEESPSSESAPAVVLSSNDDSLNSSVTEEEPVEVEVPPPETPSDDGFVHVDPSSTQKGEALKALSSIIKSEEEQANTDGDWVALSSPALKVHALDESTPPSDSSAENSVHADAAAQDQPRIISYDNVKITATNPAQDVDPTKRESYLSDAEFETLFGMSKAQFYALPKWKQSQRKLNLDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWG3</accession>
    <name>A0A8T0IWG3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G211700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWG3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="254"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1249" mass="140368" checksum="95453B51A4AE6BD3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWH1</accession>
    <name>A0A8T0IWH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phosphatidylinositol glycan anchor biosynthesis class U protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G214000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PIGU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009600">
        <property type="entry name" value="PIG-U"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121">
        <property type="entry name" value="GPI TRANSAMIDASE COMPONENT PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13121:SF0">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN ANCHOR BIOSYNTHESIS CLASS U PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06728">
        <property type="entry name" value="PIG-U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="364"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="436"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="236"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="480" mass="53526" checksum="6A38A1C4B2648EF4" modified="2022-10-12" version="1">MARWWVLWGGGLLGIAIRLLLAVMGSASLLDHRVEVVSPVTSLSRLAEGHWLKEYGMSPYAGSAYHGSPLLLSLIGPIIGDRQGSTINDLLRSCSLFVVADIISALLLRSIGQILERTHSKHFLLLGIMDPSGFESDRKDVLGAGDLSFLVYLFNPFTIAVCVGGSTSSIENMLIFVCLYGAATGKVPLAGFGWAMATHLSMYPVFLFIPIALLLANGADSPPSKLFKQSEIVAPATERDSSYQGDGKEATKPGSEELQSPPLPSSRRRWLVVLKLVLWSAISWVCILRLCKFALQGRSSLVNMWLETHKYMLTVDDLTPNLGLFWYFFTEVFDFFRTFFLMVFHANIIFMVPPLTIRLHHRPVFLAFIITAICSMVKSYPTVGDAALYMGLMALCIHELSDLQYFYILLNGYFLISVLGPVMYNLWIFRGTGNANFYFAINLVYATLQTVLIVESVSTVIRYDRNLVKQIKLQKRNKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWK8</accession>
    <name>A0A8T0IWK8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G139600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWK8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035757728" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="63" mass="7561" checksum="5D1821B599AE40B7" modified="2022-10-12" version="1">MTFFAGLCWLHLLLCYAKAERNVIELSVHWNHRILIYCRLQRSLLAFEVGGRRIHAFKIYKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY52</accession>
    <name>A0A8T0IY52_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_2G182700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the NAD-dependent decarboxylation of UDP-glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">Golgi stack membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="5"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY52"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032580">
        <property type="term" value="C:Golgi cisterna membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05230">
        <property type="entry name" value="UGD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000044">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000073">
        <property type="entry name" value="UDP-glucuronic acid decarboxylase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078:SF6">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="11" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="13" id="KW-0456">Lyase</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="NAD(P)-binding" evidence="16">
        <location>
            <begin position="124"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0587676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="441" mass="49149" checksum="A95D1FF1E0736955" modified="2022-10-12" version="1">MSSSLSHRRVEVAMGDEKYGPKVGRQWSVSKPVEYVLREQRLVFVLVGMAMTSLFFVFLQPVSRGPDRSVPDSTSVGVGGYGGGAFGTEKALEKAPYWQQQSAIVNLGGKIPLGLQRKALRIVVTGGAGFVGSHLVDRLIERGDSVIVVDNFFTGRKENVMHHFGNPRFELIRHDVVEPLLLEVDQIYHLACPASPVHYKFNPIKTIKTNVVGTLNMLGLAKRIGARFLLTSTSEVYGDPLEHPQKETYWGNVNPIGVRSCYDEGKRTAETLAMDYHRGAGVQVRIARIFNTYGPRMCIDDGRVVSNFVAQALRKEPMTVYGDGKQTRSFQYVSDLVEGLMRLMEGEHVGPFNLGNPGEFTMLELAEVVKQVIDPSATIEYKENTSDDPHKRKPDISKAKELLGWEPKVALRKGLPLMVEDFRKRIFGDHKEKGTVNSVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZA1</accession>
    <name>A0A8T0IZA1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G261500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="11114" checksum="8C70917A3E5F78FD" modified="2022-10-12" version="1">MLMPLYFLHQVGYVHFTLFSSLYKVMVDYMVAFMFISSHDQSEVHEVQKTRGFECVRGLMADEAVALFQGFYENGNQNAPRPNRPVRLEKSPHLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1T4</accession>
    <name>A0A8T0J1T4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G001900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1T4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9438" checksum="5450E72B70F85122" modified="2022-10-12" version="1">MRRRGGAWSPGLGGKLKGIQVRGSSHVYHSFTRPVGLTFLSGFMNILVLGPGHRCHGGRWAVGSGQEPGTRDIYNSLALESWTQAEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J215</accession>
    <name>A0A8T0J215_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G031200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J215"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035884781" evidence="1">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6618" checksum="432B05DBF821B791" modified="2022-10-12" version="1">MFWWWFENLGFQVWGARDHFCFCVFEVVVESSVRSVLRLSARVCGTMTPWFLLHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2C1</accession>
    <name>A0A8T0J2C1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G271000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2C1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035929681" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6664" checksum="AE2E38FA93FB64D7" modified="2022-10-12" version="1">MSCLVFLMQLNVLNCVFLIWLRMQYANGSNPGYMVFCPLSTADVGGVRMTTCRVHDSRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3B0</accession>
    <name>A0A8T0J3B0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G006700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3B0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035821760" evidence="1">
        <location>
            <begin position="17"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="7008" checksum="7C385C6354993284" modified="2022-10-12" version="1">MGSHWVCLWLLQGNDALQRCPLYYCCAHHALLAVPWGWKSSMLPQMTYRRDSDLLDQALSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3C0</accession>
    <name>A0A8T0J3C0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Coiled-coil domain-containing protein 61</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G041700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CCDC61 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3C0"/>
    <dbReference type="OrthoDB" id="1919348at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22284">
        <property type="entry name" value="HD_CCDC61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049733">
        <property type="entry name" value="CCDC61_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691:SF1">
        <property type="entry name" value="CENTROSOMAL PROTEIN CCDC61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22691">
        <property type="entry name" value="YEAST SPT2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="335"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="576"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="146"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="257"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="371"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="440"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="451"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="484"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="519"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="581"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00041518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0589712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="645" mass="73648" checksum="8249789B55DE6703" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J676</accession>
    <name>A0A8T0J676_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G097900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J676"/>
    <dbReference type="OrthoDB" id="4951845at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00299">
        <property type="entry name" value="GST_C_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00570">
        <property type="entry name" value="GST_N_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12108">
        <property type="entry name" value="Hr-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.520">
        <property type="entry name" value="nmb1532 protein domain like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35739">
        <property type="entry name" value="OS01G0861700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35739:SF1">
        <property type="entry name" value="OS01G0861700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="32"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="524" mass="59318" checksum="26C7795277C27143" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6J7</accession>
    <name>A0A8T0J6J7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G154900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6J7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000714">
        <property type="entry name" value="Transducin/WD40 repeat-like superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044285">
        <property type="entry name" value="PWP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14091:SF0">
        <property type="entry name" value="PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="278"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="30"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="258"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0591165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="395" mass="43208" checksum="9008FCA9F8F1C803" modified="2022-10-12" version="1">MIAAVCWVPKGAAKNVPIVAEPPTEEEIRELLQHAESAQQGEGEEEDDEEDGEGEEMEEAEPSAVETALAAATALGATVKAHKSYEETLADGLAELDMDRYDEEDEEGVELFGNGGLGAAFYPSNDDDPYLVDKEDDDEEEIEDMTIKDSDLIVLTARNEDDVSHLEVWVYETEESVSEDPEEGNMYVHHDIMLPAFPLCLSWMDCNPKGEGKGNYVAVGTMQPEIEIWDLDVVDSVEPVCVLGGALEGAVGEESSEKKKKSKKKKSKAKAKEVKYKEGSHTDAVLGLSWNSEFRNVIASASADKSVKIWDIVKGTCEHTMNIHTDKVQAVAWNLKEPTVLLSGSFDRTVGLTDESSSSSCHPLVCFCRCGISSLGSAHVAHVSSKFRGRNCWRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7Z2</accession>
    <name>A0A8T0J7Z2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="6">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_1G132500</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RBR family. Ariadne subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7Z2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031090">
        <property type="term" value="C:organelle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20341">
        <property type="entry name" value="BRcat_RBR_RNF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20336">
        <property type="entry name" value="Rcat_RBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23821">
        <property type="entry name" value="RWD_IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000051">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="12" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <keyword evidence="11 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RWD" evidence="19">
        <location>
            <begin position="86"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="20">
        <location>
            <begin position="275"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="18">
        <location>
            <begin position="279"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0590881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="634" mass="71572" checksum="23FF46B9F07DF753" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8K9</accession>
    <name>A0A8T0J8K9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G165500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8K9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035877873" evidence="1">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5991" checksum="C9DA5F7B2B879FD8" modified="2022-10-12" version="1">MGILAALRLLLFRFIFKNFFLRFQGFLKLEYPTRLKLKVWNPVAMQKWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCD1</accession>
    <name>A0A8T0JCD1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="3">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_1G271700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="3"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCD1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044027">
        <property type="term" value="P:negative regulation of gene expression via chromosomal CpG island methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23138">
        <property type="entry name" value="RING-HC_ORTHRUS_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.280.10:FF:000002">
        <property type="entry name" value="E3 ubiquitin-protein ligase ORTHRUS 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000665">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.280.10">
        <property type="entry name" value="SRA-YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047498">
        <property type="entry name" value="RING-HC_ORTHRUS_rpt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036987">
        <property type="entry name" value="SRA-YDG_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003105">
        <property type="entry name" value="SRA_YDG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045134">
        <property type="entry name" value="UHRF1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14140:SF27">
        <property type="entry name" value="OS04G0289800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02182">
        <property type="entry name" value="SAD_SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00466">
        <property type="entry name" value="SRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51015">
        <property type="entry name" value="YDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="14">
        <location>
            <begin position="9"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="146"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="YDG" evidence="16">
        <location>
            <begin position="272"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="508"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="93"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="469"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="591"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="642"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="723"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="591"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="610"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="658"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="767"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="796"/>
            <end position="822"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0592673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="862" mass="94692" checksum="151333D39F0C839F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCF4</accession>
    <name>A0A8T0JCF4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G297600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCF4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16275">
        <property type="entry name" value="BaeB-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051453">
        <property type="entry name" value="MBL_Glyoxalase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46233:SF3">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="5">
        <location>
            <begin position="157"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0593006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="40847" checksum="83B44C65F2A136B0" modified="2022-10-12" version="1">MEALKDQGNDAVRRKDFHAAVDLYTRAIEAAKACAVPDHEVAPLHSNASFACLKLGDFAQARAHAGSAVAANPTWSKGHFRLGEALFATSDYAGAEKAYSRASELAVEDVTLKKKVALAREAMAGFYFRQLLAGRDFAVSAGNMIERQIFSSAKQMQNYVYLVGDARTREAVVVDAAWDVKGIRSFAAAENMKLVGAVVTHYHFDHTGGTPPPPFDQLGIKVPGVRELAVEDKLPVYVNKDDAKTVMKSNGVPSESLTLLEDGGEVSIGSVKLKFIHTPGHTPGSQCIHIERPEQDILISGDTLFIGSCGRLDLPDCNAKLMYNSLQKKLSALPATTRVYPGHDYGGPYTTISREREQGFLKPMNEGEWMRMHGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G2Q9</accession>
    <name>A0A8T0G2Q9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G008600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G2Q9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="15535" checksum="33A4C6D1A2D8A270" modified="2022-10-12" version="1">MHPVNTPLIQTTPQNTAQYLCKTSIFLSRFSFCISETPPLPFTSRNTTPATKPASLTHPNNQPYQRNRNSTRNSTVTKPPPKQPTPSTKPKLHPKLNCQKTATKGIKTTASNKQNRQKKGRNQTKNRQRNPYTLRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4C3</accession>
    <name>A0A8T0G4C3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G061900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4C3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035894628" description="Secreted protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7874" checksum="A1216DE2A1B64434" modified="2022-10-12" version="1">MVALCGRNLWILLVDSLETFGIFLPCCCAGALRERDLLGGVVSLLEIWKFPCSVAVIVVQECGLCGVRRALY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6W7</accession>
    <name>A0A8T0G6W7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G102400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6W7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.80:FF:000003">
        <property type="entry name" value="WRKY transcription factor 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044810">
        <property type="entry name" value="WRKY_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221:SF334">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR 57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="7">
        <location>
            <begin position="370"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="222"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="431"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="486"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="564"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="253"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="347"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="456"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="589" mass="62048" checksum="F7745FCDAE787B92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G858</accession>
    <name>A0A8T0G858_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 11">NADPH--cytochrome P450 reductase</fullName>
            <shortName evidence="10">CPR</shortName>
            <shortName evidence="10">P450R</shortName>
            <ecNumber evidence="10 11">1.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G169700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>2 oxidized [cytochrome P450] + NADPH = 2 reduced [cytochrome P450] + NADP(+) + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24040"/>
            <dbReference type="Rhea" id="RHEA-COMP:14627"/>
            <dbReference type="Rhea" id="RHEA-COMP:14628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:55376"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="1.6.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="10">Binds 1 FMN per monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Single-pass membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NADPH--cytochrome P450 reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10 11">In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.2.4" evidence="10 11"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G858"/>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003958">
        <property type="term" value="F:NADPH-hemoprotein reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06204">
        <property type="entry name" value="CYPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03212">
        <property type="entry name" value="NCPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023208">
        <property type="entry name" value="P450R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF17">
        <property type="entry name" value="NADPH--CYTOCHROME P450 REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000208">
        <property type="entry name" value="P450R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 10" id="KW-0274">FAD</keyword>
    <keyword evidence="1 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="12">
        <location>
            <begin position="72"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="13">
        <location>
            <begin position="280"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="78"/>
            <end position="83"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="134"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="460"/>
            <end position="463"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="494"/>
            <end position="497"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="543"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="603"/>
            <end position="604"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="609"/>
            <end position="613"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="645"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="683"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0555443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="683" mass="75386" checksum="14722BF14C60921A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9M6</accession>
    <name>A0A8T0G9M6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G021400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9M6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035757086" evidence="1">
        <location>
            <begin position="35"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="18040" checksum="AF59FEDD2B507E0A" modified="2022-10-12" version="1">MAPTSFCKSSWACLPVPLLLAAVLVGSLAIGANAQTPLSFSLTVDNNLDSGPFANNADCTITSQQLLGGPAVTFSVPAQGSNTVTLQATRSLLSPSFRVTVYGKGPLGSCTFFFFNCGVGTTYTTSGNLLSRVASLTGYRIVIVGNCGTSNRPALRLDGYALGGTTPDTTTCAQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAL7</accession>
    <name>A0A8T0GAL7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G167700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAL7"/>
    <dbReference type="OrthoDB" id="1043111at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17039">
        <property type="entry name" value="Ubl_ubiquitin_like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="82"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="20838" checksum="F247C170F3B3555F" modified="2022-10-12" version="1">MVKKIYSQMAPNATVLQMMQKIHNKKGIPIHEMQLTYNNRQLEEDKSLAYYGINNGATVVLKTYSRTVDCPCEDCQRMEKKVTITVTWLQKSIKVECRLGEPVESLKNAIRNQEGISVAKQKLSFNGLELEDHKLLASYKFGDAESGGAEAVVHMFVDSGDPTLFDKLRSTFSFKGAKSVTVPTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB40</accession>
    <name>A0A8T0GB40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G140000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336:SF3">
        <property type="entry name" value="GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43336">
        <property type="entry name" value="OXYGEN SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS/DOSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="83"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="359" mass="39946" checksum="4A56FB717819A0FD" modified="2022-10-12" version="1">MVEIVKELSDDPVSFAAKANLKQPANTTFGQVMETRVVEGALVKIASLSKVALGDAGMDILSVNLKGGSEFNPMIPGKKIRACFGFCDIRNFTDATECLQEDVMMFVNKIADVVHNKVVFHQGFPNKNIGDAFLLVWKKSAADSTQKTRGTNSFADRALQSFLDIIQCIETSQTLAEYAMHSAIQKRMPGYKIHMGFGLHVGWAIEGAIGSAHKVDPSYLSPHVNVSSRLEAATKQYGVMMLISETVIAELTKSSLRHCCRKLDRITVKGSAEPIIIYTFDMPLFQQDLKGNPSDYRALFENAVDNYIEGNWSSALEKLEECLQLWPTDKPGHVLLNFMASHNYRIPANWKGYRELTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBK6</accession>
    <name>A0A8T0GBK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VPS9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G053200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBK6"/>
    <dbReference type="OrthoDB" id="411646at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005769">
        <property type="term" value="C:early endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030133">
        <property type="term" value="C:transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097422">
        <property type="term" value="C:tubular endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045022">
        <property type="term" value="P:early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.80">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051248">
        <property type="entry name" value="UPF0507/Ank_repeat_27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003123">
        <property type="entry name" value="VPS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037191">
        <property type="entry name" value="VPS9_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24170:SF1">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02204">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109993">
        <property type="entry name" value="VPS9 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51205">
        <property type="entry name" value="VPS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VPS9" evidence="2">
        <location>
            <begin position="182"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="449" mass="49606" checksum="ACB9AB8C882A15E7" modified="2022-10-12" version="1">MKFPFRRRKSLPRGKSEEGSGGVSGVKARIQLRLLSQLKWEANAPKKVKGEKAEKVRQVQPAVVKALWPDLDTLEGCTEFLKSSGLNTRALAHAARMVDHFKSSYQMGDSSLPDEFRIEAWKGTLRRIVKTLVDQLLASNPRLESACVGNEESMGQLWSACETWVLGSVYDKIMGACKQMFGQSDKILDDNLARLDKVDPIVLGVRSEFKEFVLGEALLQFRMINRGRTPLEKAICLRKTINCIIEGIQTVISSCSGTSAEKDGLLPCTDDLLSFMLLLMARSRVKNLQANACYMHNFLSLQMEDEQSGELAYHVTNFVAACNYLNTGEVEKLLATVPVPSNTETTPTSVKSPGSVASSPPIVTPVYNRSYSFEPDVHTMSGGEIFTVNMFDGQSSGRRRSQGEIELRSFSEKNLGESGFRGSSMSKGGDLNLAFARDSPEFILAPTYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC73</accession>
    <name>A0A8T0GC73_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G181700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC73"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14454" checksum="469A404F082A37F4" modified="2022-10-12" version="1">MSSSYEKVRGGKLSFKGGLGPEKTLDKKKHKKKKLKKDPVPEGEGEEVAVDATGEKEKEKEKGGEDDKDAKARDAIDTGTGHAPDGKKSKKYEELFPVETKRFGYVIPQAKSREAALDERVKKKADRYCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGV4</accession>
    <name>A0A8T0GGV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Acid phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G014400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histidine acid phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07061">
        <property type="entry name" value="HP_HAP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033379">
        <property type="entry name" value="Acid_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050645">
        <property type="entry name" value="Histidine_acid_phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567">
        <property type="entry name" value="ACID PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11567:SF207">
        <property type="entry name" value="LYSOPHOSPHATIDIC ACID PHOSPHATASE TYPE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00778">
        <property type="entry name" value="HIS_ACID_PHOSPHAT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="46022" checksum="AB86829CB2E403D7" modified="2022-10-12" version="1">MAMESLPPSPVCPAAPQLLEVHVYFRHGDRSPTPLGEAKAQTELWASRVQEVPVALQNREYFPQKYPWGLLTMKGAQQARELGAWLREHYIPKFSKTNGEVILRETPEKFLSLRTTNFLRTNLTAWFLLEGFLESPEIAATIPFACREEKDENLYHNEHCPRLQLKWKQAWAAVKRAVGQDGVNWRERFKDMQAAMARALEIELGNPKFSQSMDGEGFPWITAVDTFECARFHGDPLPEGIAEENVMAVRTLLAEDYAASFHDRDVLQLSIGTLVRELKEALVSRVNAPESPARPSLYLYSGHDATIMPLSVAFGVPWTVWPSYTSSICVELWRTQDGEHYVRILYDREEVAIPVSRAERAPKKVMLSLEEFSEVAEWSVLSSTDFSSRCQDISDIIPTPNRIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIQ5</accession>
    <name>A0A8T0GIQ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G174900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1410.10:FF:000005">
        <property type="entry name" value="Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF134">
        <property type="entry name" value="OS01G0976450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="57"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="288"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0558039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="50609" checksum="26E00E8FE8460E3A" modified="2022-10-12" version="1">MPLLRCTAGHVGTLGLRACLGQRVAHSEFSSLLSWLESRGETGAQTSLTIGNTANQGRALVTIRSVKRGEQMLRVSRELMITPNRLPPGVDDCLSEDVNEWSRLALFQLLHRHAGKASPWEPYIKSLPPLRELHSTVFWRDEELELLHESSLYDQTEHRKTLILTQFDTIQAAVNKFPQLFGETVTLESFTHAYCIASSRSWGVEALGSITMVPFVDMCNHDSHSRALLAYYEEEGYAEVVADKDYNQGSQMVITYGTFSNSSLALDFGFTLPDNPHDEVQIWMEVPSEDPLRAEKLELLYGHGFETKAFCDSSESGGAWFGLREVSSPAARGKGIPRALRTFARVLSASTLKELQAMAEDAKRRQCRLGERPLKDGKEARALKILLDTVDQCQSSHRSALKKVQRAQDTPQIQAERAKMAGDVLEGELRVLCSVAAWLRPRAQGGGYEFLNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIZ1</accession>
    <name>A0A8T0GIZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G007400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIZ1"/>
    <dbReference type="OrthoDB" id="1679871at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="217" mass="24580" checksum="98E8DA791947C03D" modified="2022-10-12" version="1">MADAEITLPPVHAMQAECRVQIHDDLKLRLSLQEWENNFKRALVRIENKRTRSLSVKNELYQLISFYSVFQGVVLTAVAQASTLKCHTAWGPASLSAIASIATLFGVHNKLIDYYVLKSELKKEEDDANVTKEKISLLKLRGKDFKFSVLDEKANAVEKRPKVQSSAKYYWLVMIPLILFSVVVLICGISILCSDADPSRTLSFRLQSNVELVRNKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJL0</accession>
    <name>A0A8T0GJL0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein Iojap, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G085800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="6">Interacts with chloroplast ribosomal protein uL14c (rpl14).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJL0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000026">
        <property type="entry name" value="Protein Iojap, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF2">
        <property type="entry name" value="PROTEIN IOJAP, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00069129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27725" checksum="5A84FA736A073623" modified="2022-10-12" version="1">MPHPHQVLALQQCNPTSLWQVPTSSCGHSLSVRAQASPCTSMPVLQVASSSGVRTKGFSLSSQRFMVSPRTASQRCNSISNTPTGRNTEEMQDAEFDQLGEDDLDSLFEEYGETVKNDAESSNVTSEVDDDSDSLAFAVALAEAANDVKGSEIQVLCVKPLIYWTRFFVVVTAFSKPQIDAVGKRMRDIAEEKFNRSPKGDSKPNAWTLLDFGDVVVHIFLPKEREFYNLEEFYGNATLVPLPFENRSMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKD9</accession>
    <name>A0A8T0GKD9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G147700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKD9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12066" checksum="DF7545A786DFA0C5" modified="2022-10-12" version="1" fragment="single">ITLCLLSIKGDPQSETKASLALSLPLFQEETTYKPESNELSLSQPLKKSPQRFPTTSRIATTLNLPPPKTSALLQTLPNMLSIIQELQSETRASRELALPKETTYKPQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLL1</accession>
    <name>A0A8T0GLL1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Malic enzyme</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G135000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004473">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05312">
        <property type="entry name" value="NAD_bind_1_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10380:FF:000023">
        <property type="entry name" value="Malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000182">
        <property type="entry name" value="NAD-dependent malic enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="entry name" value="Malic enzyme, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminoacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010052">
        <property type="entry name" value="PRK13529.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406">
        <property type="entry name" value="MALIC ENZYME-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23406:SF64">
        <property type="entry name" value="NADP-DEPENDENT MALIC ENZYME 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00072">
        <property type="entry name" value="MALOXRDTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="Aminoacid dehydrogenase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Malic enzyme N-terminal" evidence="9">
        <location>
            <begin position="97"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Malic enzyme NAD-binding" evidence="8">
        <location>
            <begin position="288"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>(S)-malate</name>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0559860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="578" mass="63861" checksum="51189EA0FEECF592" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMM0</accession>
    <name>A0A8T0GMM0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G131500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMM0"/>
    <dbReference type="Proteomes" id="UP000822688">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="262"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="483"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="331"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="349"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="490"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="552" mass="58730" checksum="88E2BBC56C50A5C0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN14</accession>
    <name>A0A8T0GN14_CERPU</name>
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        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
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        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G025700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17963">
        <property type="entry name" value="DEADc_DDX19_DDX25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="10">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="135"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="340"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0560936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="509" mass="56590" checksum="274A66DFA17DA2D4" modified="2022-10-12" version="1">MADKDAVPPPAEEMKVEDAKPETETETKAAEPAPAPAPAPVPAKKLWSDEDFGEVDFTGLKVGEPVDDIVDTPERIKSEAIVEPETIKKVVADDTPYTSALSFEDLNLSPELLQGLYSEMKFEKPSKIQAATLPMIVTPPYKNLIAQAHNGSGKTTCFVLGMLSRVDPQLKAPQALCVCPTRELVIQNEEVVTRMGKYTGITTACTASAETSSHLYPSRREKIVDQIVIGTPGTLKRWMTKDKALDTRNIKILVFDEADQMLDQDGFQDDSIRLWRDIVRSGGKCQVLLFSATFSEKVKNFSLKTIPGANYIFVEKEQLSLDVIRQYQVVCPDARSKINVLKDRIFPAAEKLGQSIIFVRTRGSASELHKRLEADGHKCTSIQGGLTHEERDRVIKEFRAGETKILIATDVLARGFDQAQVTLVVNYDLPVKNTPNRNAYAEPDFETYLHRIGRSGRFGRKGAAFNLLVTEEDKRNMRKIEQHFNKNVPEVAWDNDDGIESVLKAAGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN64</accession>
    <name>A0A8T0GN64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G085400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="13017" checksum="5299E4B77DBD50F4" modified="2022-10-12" version="1">MNFPKKGGSGNWRRTPRGQRRGAPSDTHPTDPIAPRFLPTSRLSSFGDAPFCKSWSSSTRHPSHPFHVFRAIAPPNPSITSSLPIGAYFQKPHSQLPLCLCDPHPVCITAVSELRVVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNE4</accession>
    <name>A0A8T0GNE4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G035200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNE4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="14952" checksum="032EC1376FE301F2" modified="2022-10-12" version="1">MAPAEKFSCKSKREGDACVSKLVVISEVGEARGKPTVQAAIERMNRAKILNGGGRLPQKRGYVSLNLIFYLEEVMLLKTKCVNVELKYGSCWSCATGEEKNLRRCQGLPRNMCDDFEGTHVLPLGGGMRGVCSLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPI7</accession>
    <name>A0A8T0GPI7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Tyrosine specific protein phosphatases domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G177900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14527">
        <property type="entry name" value="DSP_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47216">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47216:SF4">
        <property type="entry name" value="OS01G0859400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="3">
        <location>
            <begin position="201"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="288" mass="31670" checksum="4B12E6A2583CD04F" modified="2022-10-12" version="1" fragment="single">ATSTTRTPPPESPPKPPKAPPTPKCPSPPTQPPHSSPNCHLLGQLAMGISLVVGLPSAAVLAAFVALRQSNAPPYITLPVLHSSIVGFTAAIAAHPRINYTGLFRKSREGAFPWWSYAAFYPYLLTLRAYVHARRFLSQEPVFTEVEPGLFVGGWPALQRDVPPGLRGVVDCTCELPRNSCVNELPYLCVPIWDTRGPQPVEIENAVQWALKQRGESGHPVLVHCAFGHGRSVTIMCALLITLGVCDTWQNAETYIKRSRPRARLNKGQKESLKEWQSVFASKQEKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="3" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRP9</accession>
    <name>A0A8T0GRP9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G050200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6666" checksum="41D955BE49123F8B" modified="2022-10-12" version="1">MLAVPCRSSDCLDQFGWVRFLGGPELVGTRTRTRRNWNSSPTRSRTMWNVFCEEIML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GST5</accession>
    <name>A0A8T0GST5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G008300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GST5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="386" mass="43417" checksum="7DDA6DDE9EC59125" modified="2022-10-12" version="1">MVQPRLSVGTSKYWLRARSGNRNGGKILVSVDSLYSIFKENRVRSTPKKAEVPAAVIPATTTSSRNAPGTSPALPTIRKSARLFEKRAALLRCTRGPQYWLRTRSRGNKRSLLVSVKSLYASEAREHNVKEDHDKNTKTCSGCCQQTPQRRKSARLFEKRAASLLSCRTGRPGGVHRKMSKFKRKKKHICWLYKGTPWLGGCYNSKFSAHIRSKGLRVNCDSGNKDRGADIASPCSGKRFHDPACRPVLQRLTERGEEDLLQSILEKLPPANLLQAARVCRSWARLCEPAFREECHRKGWSLPRLPRGATPAFPWRSLYYRHACRACGKVGEFFVRKTLNGNFQFLLCGGCIRLPDVRNRLVQYSIDLYGVTGKLLAPNVSSRGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GST9</accession>
    <name>A0A8T0GST9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G113600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GST9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="8001" checksum="879CB64A2BF3A174" modified="2022-10-12" version="1">MVPSCSGVGVRGGSETLQAEPSVCPFSLRNKERGPQRAPAGQPPTPGPAPSSSSTTSQIQTSPQPSLSSLIISVEFHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTW0</accession>
    <name>A0A8T0GTW0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nematode resistance protein-like HSPRO2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G139800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTW0"/>
    <dbReference type="OrthoDB" id="188455at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:L-tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009743">
        <property type="entry name" value="Hs1pro-1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038759">
        <property type="entry name" value="HSPRO1/HSPRO2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009869">
        <property type="entry name" value="HSPRO1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34795">
        <property type="entry name" value="NEMATODE RESISTANCE PROTEIN-LIKE HSPRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34795:SF1">
        <property type="entry name" value="NEMATODE RESISTANCE PROTEIN-LIKE HSPRO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07014">
        <property type="entry name" value="Hs1pro-1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07231">
        <property type="entry name" value="Hs1pro-1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="Indolic compounds 2,3-dioxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nematode resistance protein-like HSPRO1 N-terminal" evidence="3">
        <location>
            <begin position="40"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Hs1pro-1 C-terminal" evidence="2">
        <location>
            <begin position="196"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="494"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="509"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0562353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="555" mass="61840" checksum="A6C30FF46E0032EA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW43</accession>
    <name>A0A8T0GW43_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G067200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="10031" checksum="DD59DCC220160E31" modified="2022-10-12" version="1">MRIKARLVLIQEGRPRPWRWWPSLTQRATHQIVCIDIASGSPSIPRDTALAPIWHQPNSPFPHPWPCSGGFFPLMRLTFAGEPSDLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXH2</accession>
    <name>A0A8T0GXH2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G113100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="282" mass="31252" checksum="724555CFADCD514F" modified="2022-10-12" version="1">MPSLQTMEYLGRLGLVPRKNKKERVASLPHVTESEETRRCSVEVSAGGDRSCKPGLPVDTTPCPLETGTNIKCAIKEPISGTAQDETAHTQQATAFVEIRDTLSTDLSTRADLNFDMADSFFPRTSTSGQEAVIDIEFMEYEQHVQARAKVLADENFGAPGGRHAWKTLIFWKRRRTVPTSTRRTFVSAASTPLYHPPFQALPGRKSYHGSRRSINPATVPLYMSHDEFSSSSIRPWWEPMMRGSGKISMAGGQDSKFCNMSPYVSLGGQPQRVPIAPLYVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXS3</accession>
    <name>A0A8T0GXS3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G014400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035943972" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8749" checksum="F02944D70EE00C77" modified="2022-10-12" version="1">MIVCVVVALLEFVGTAYGARDQLAGHKGVQMTHESSASTLAFGQQSLFEWPCSNPFCDGSTWFICSCNVGVCSCSCHHSAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ37</accession>
    <name>A0A8T0GZ37_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G101700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14554" checksum="E6A957D5F59F2E2C" modified="2022-10-12" version="1">MRENRRERAKERERERAPSPVPKLITPHSPSPSPSPSPLPSRSAVASRDPNPPPHRHALLTTHPKGLHYGTSHQRTSHPWGWLKFLLYFRRLGEGDLALSLQLVGCRRGQDLRVTRLELTIIRVVVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ48</accession>
    <name>A0A8T0GZ48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7748 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G028200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056650">
        <property type="entry name" value="DUF7748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468:SF1">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24928">
        <property type="entry name" value="DUF7748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7748" evidence="1">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="13514" checksum="C91E15E533C4FF72" modified="2022-10-12" version="1">MSTKVRTMIVNATEQPLTMKVGNRNCFFRLASVKKGGEYAMELCMDWTYQEFMLEDKSDSGRKLFVNSDDCCDYERITVTESDGKLLIVRVPRKRFQSCEQTSTKKSKLTWRFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ99</accession>
    <name>A0A8T0GZ99_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G107000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035811659" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="96" mass="10676" checksum="96DD265AA899B633" modified="2022-10-12" version="1">MPRRACVSILLLLENLPLTMSTRNSCSQLTAYSSRGASRVKIIIFTYVELALTGTRDLKFNALIFRSPCSPIIQGPREGQGNLLMDESMGFETLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1W2</accession>
    <name>A0A8T0H1W2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome b5 heme-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G133400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the cytochrome b5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1W2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.120.10:FF:000002">
        <property type="entry name" value="Cytochrome b5 type B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.120.10">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001199">
        <property type="entry name" value="Cyt_B5-like_heme/steroid-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036400">
        <property type="entry name" value="Cyt_B5-like_heme/steroid_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018506">
        <property type="entry name" value="Cyt_B5_heme-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050668">
        <property type="entry name" value="Cytochrome_b5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359">
        <property type="entry name" value="CYTOCHROME B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19359:SF141">
        <property type="entry name" value="CYTOCHROME B5 HEME-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00173">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00363">
        <property type="entry name" value="CYTOCHROMEB5"/>
    </dbReference>
    <dbReference type="SMART" id="SM01117">
        <property type="entry name" value="Cyt-b5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55856">
        <property type="entry name" value="Cytochrome b5-like heme/steroid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00191">
        <property type="entry name" value="CYTOCHROME_B5_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50255">
        <property type="entry name" value="CYTOCHROME_B5_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Cytochrome b5 heme-binding" evidence="9">
        <location>
            <begin position="9"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0564715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="148" mass="15981" checksum="4427707759173CFE" modified="2022-10-12" version="1">MASEGEDQKTVYTLEEVGQHVAQDDCWMVINGKVYNLTSFMDDHPGGDDVLLQVAGRDATNEFEDVGHSKAAIEQMQDFFVGKCPQVFEKAELLSVTEGDLAIGGSASPPAPTNSVGIWSKILQFLVPLVFLGIAVAIRNVGKKDPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H386</accession>
    <name>A0A8T0H386_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_8G176000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H386"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000162">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035841037" description="Protein kinase domain-containing protein" evidence="16">
        <location>
            <begin position="29"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="425"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="487"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0565247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="820" mass="91407" checksum="F433C6169BC0B0BA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4J5</accession>
    <name>A0A8T0H4J5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G078500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4J5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="2" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="97"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="741" mass="83467" checksum="43539982A0F9A943" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N7</accession>
    <name>A0A8T0H5N7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G031000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055301">
        <property type="entry name" value="Lea14-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004864">
        <property type="entry name" value="LEA_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31852">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03168">
        <property type="entry name" value="LEA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Late embryogenesis abundant protein LEA-2 subgroup" evidence="2">
        <location>
            <begin position="83"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="22412" checksum="00DD77C68DD5EC8E" modified="2022-10-12" version="1">MYPGVFTRPGEPSLTMSEYEEKRRKKRMWLTIALLIVVVIIIVVILALTIFKAREPKLGINSIDIETFSIGVDSLNMSLLLDITVYNPNRADFTYSESVARMFYYGDAVGQAFIPAGTIKSKADEFLSVLLFVEAARVLVNEHLPGNIVSGILPVVATTTLNGIVRVFGVFKHHAVTTSDCDITVFVANATLQSFNCKHAVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H900</accession>
    <name>A0A8T0H900_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G126400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H900"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035790162" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="87" mass="9262" checksum="A97ACD81C60F968E" modified="2022-10-12" version="1">MRSPRHIISKSMALLSVSLCSLYSSPDRSVTIDIVNFMIIRAYSESGFSPDGMAASLKPAPLTRASTRSKVVIPANLPVSANLSPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H935</accession>
    <name>A0A8T0H935_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G130500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H935"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22895:SF0">
        <property type="entry name" value="ARMADILLO REPEAT-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="68"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="633" mass="70345" checksum="90378612AD127A83" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCK3</accession>
    <name>A0A8T0HCK3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G131000</name>
        <name evidence="6" type="ORF">KC19_6G058200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCK3"/>
    <dbReference type="OrthoDB" id="2014773at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1120.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="entry name" value="Ribosomal protein l15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_eL15_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_eL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_eL15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003269">
        <property type="entry name" value="PRK04243.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847:SF4">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="RIBOSOMAL PROTEIN L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0554928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="24256" checksum="97656881C92EADD9" modified="2022-10-12" version="1">MGAYKYIEELWRKKQSDVLRFLLRVRCWEFRQLPGIVRVTRPSRPDKARRLGYKAKQGYVVYRVRVRRGGRKRPVAKGIVYGKPKNQGITQLKFQRNLRSVAEERAGRKLGGLRVLNSYWINQDSTYKYFEIILVDPQHTVIRKDPRINWIVNPVHKHRELRGLTSAGKKYRGLRGRGHLYTKARPSVRATWKRNNTLSLKRYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEC3</accession>
    <name>A0A8T0HEC3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G139500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37244">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37244:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="380" mass="41148" checksum="81B53662AC1D0C98" modified="2022-10-12" version="1">MCEAMVGEESETALPRVRQSKPTEKESQCLSPNTPLGFSKFAIETEWGEMEDFDEVAGGPLCVSHAAASSPGSYGFLSPTGSAQSWFDIRVIYLRVAGCALEEAPETLTIRFPPRSIGVALEVNGGWISPSEEACVALRRDRVDTETTEATYVSTDNIRMSETICFEVFNKEEALVSGTLEHSSGSQETGHGSSDSGSRKGERTWSMECCCVVGKSGCAFLKSRHDFSAPLSPPAMEVSMVGRHLDTPVFLTQTVNLIARRKLSRILTLDAIPETEELGKSQNDLLKFGEPGLISQRDAFAGFENTTSFSDFSDKFAAGISQLDDRLYGIEGDDGQMTWFNAGVRVGVGIGLGMCLGAGIGIGLMVRTYQVTTRTLRRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF19</accession>
    <name>A0A8T0HF19_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G040200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF19"/>
    <dbReference type="OrthoDB" id="1921208at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0052">Apoplast</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035964433" description="Germin-like protein" evidence="10">
        <location>
            <begin position="28"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="11">
        <location>
            <begin position="62"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0568709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="223" mass="23881" checksum="D919A2A757E69AAD" modified="2022-10-12" version="1">MAQYKGAIMFQLVMVVFMGAALLGAMASDPDPLLDFCVSTGDLYSSCKLKEIVTSNDFIYKGTASPGDPTKDPSGFVQTPAQVTQFRALHTLGISIVRLSYAKGGLVNIHTHPHASEMVYVISGKLYVGFVGSDNKLYDGYLEAGYTTVIPRGLVHFSMAVGDDPVYAIAAFNSENPLTQIIPNALFGKSNIPDAVLSKGIGINVATVQSIKDQFRKTYGNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGC1</accession>
    <name>A0A8T0HGC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G107100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="15193" checksum="C289541A31A7198B" modified="2022-10-12" version="1">MFEGDWTIPLAFHGCSGCFPKASYVNTPCVASNYYIIAEVNQRQVAFPGYEQIIKLHSVVSDDNLDISWGSFRAVDFKREYIPFSLFLQLVPTCFRALFDMEARCILVYMTTARSLEHIQKLRITGGNSAASQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH24</accession>
    <name>A0A8T0HH24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G160100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11355" checksum="FA8D721AC7BAA29A" modified="2022-10-12" version="1">MLHTAIIPGKAHPDAAKPHTETLPSSHDKGILFPKEVPTVSVQKLTCSLYVSPLNYPRSGKAQPLLKVKSAYFWNSNLRLHIAIRASVQQTLIVILRSPKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHE8</accession>
    <name>A0A8T0HHE8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7953 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G029900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057713">
        <property type="entry name" value="DUF7953"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33780">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33780:SF3">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25829">
        <property type="entry name" value="DUF7953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035877367" description="DUF7953 domain-containing protein" evidence="2">
        <location>
            <begin position="47"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7953" evidence="3">
        <location>
            <begin position="49"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF25829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="248" mass="27911" checksum="62E34C914D2AAB52" modified="2022-10-12" version="1">MAINRAHSESSLLTSTSQPMSIRGCRALLSLLSLCILLLAASGVVADGNVTLESLTIFTTHEWFGQKPDVYFRCQGDERERVDLPDVKAKGQLYKFLGEESWQPLTILVGKKCKRCGIYEKDTLKSDDVFDEWELCPLDFSPSPEGVYSHFKENEFNLTLLCPTCNVVSSAEEAVSEPASEPVEKEKSHGHGLTVAIVLFVLLSLGGFAFVAYTMWRRKQREMQQARFIKLFEDEDFLDDELGLKDDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJE7</accession>
    <name>A0A8T0HJE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 19">Peroxidase</fullName>
            <ecNumber evidence="4 19">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_6G197300</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 19">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="16 19">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16 19">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="16 19">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 19">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="19">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="4 19"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000009">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 19" id="KW-0349">Heme</keyword>
    <keyword evidence="19" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="11 16 19" id="KW-0408">Iron</keyword>
    <keyword evidence="7 16 19" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 19" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 19" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="19" id="KW-0964">Secreted</keyword>
    <keyword evidence="8 19" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035961945" description="Peroxidase" evidence="19">
        <location>
            <begin position="31"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="20">
        <location>
            <begin position="31"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="17">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="41"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="74"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="122"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="18">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0570920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="321" mass="33731" checksum="3E79FBD97157C33F" modified="2022-10-12" version="1">MGSKVAAPSTASILLLLMVAVFATLSTTHAQLSTSFYKSSCPNAVNVITSAVNTAFNKRAASAAGVLRIHFHDCFVRGCDASVLIDSPSEKDARPNLSLQGFEVIDAAKTAIEKQCPGIVSCADITAMAAQLSVKKLSGGKFTWAVPLGRRDGLTSSAADTTGKLPPPTANVATLKSIFAAVGLTTEEMVTLSGAHSVGVASCGAIQNRLTTPPDATLDPTYAAALKQQCPAGSTNKVNLDLTTPTRLDEVYYKNLQARKGLMTSDQVLQEDPETQPMVAQHTNLAVFNSKFVAAMIKMGNIGVLTGTQGQIRLNCRKFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK95</accession>
    <name>A0A8T0HK95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G220800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK95"/>
    <dbReference type="OrthoDB" id="5348404at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005178">
        <property type="entry name" value="Ostalpha/TMEM184C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23423">
        <property type="entry name" value="ORGANIC SOLUTE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03619">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01417">
        <property type="entry name" value="Solute_trans_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="457"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="519" mass="57454" checksum="BDCC5BEF3826122E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMC0</accession>
    <name>A0A8T0HMC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG057700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12093" checksum="CE556270124A05A6" modified="2022-10-12" version="1">MPTSNEPAPIGLARSHENSPIDDLADDSQADDWEDTQCIPDTQRGNTPQTSTQGFGDSRHMQFAQPPPMYPVGNPFGFDSHHHPIGDGQMYGFRNFSQGLNLNARFFSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMU1</accession>
    <name>A0A8T0HMU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Arginine decarboxylase</fullName>
            <ecNumber evidence="5 14">4.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_VG070200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11 14">
            <text>L-arginine + H(+) = agmatine + CO2</text>
            <dbReference type="Rhea" id="RHEA:17641"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="EC" id="4.1.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 14">Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.19" evidence="5 14"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:L-arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06830">
        <property type="entry name" value="PLPDE_III_ADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000001">
        <property type="entry name" value="Biosynthetic arginine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003763">
        <property type="entry name" value="PRK05354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01273">
        <property type="entry name" value="speA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="ARGININE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295:SF1">
        <property type="entry name" value="ARGININE DECARBOXYLASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001336">
        <property type="entry name" value="Arg_decrbxlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01180">
        <property type="entry name" value="ARGDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 12 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0745">Spermidine biosynthesis</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="15">
        <location>
            <begin position="121"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="537"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001336-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0572122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="690" mass="76557" checksum="359C37F2E90AC781" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNP2</accession>
    <name>A0A8T0HNP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SWIRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_VG093600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the flavin monoamine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0141052">
        <property type="term" value="F:histone H3 demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000507">
        <property type="entry name" value="Lysine-specific histone demethylase 1 homolog 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000064">
        <property type="entry name" value="Lysine-specific histone demethylase 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050281">
        <property type="entry name" value="Flavin_monoamine_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013257">
        <property type="entry name" value="SRI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742">
        <property type="entry name" value="FLAVIN MONOAMINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10742:SF410">
        <property type="entry name" value="LYSINE-SPECIFIC HISTONE DEMETHYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08236">
        <property type="entry name" value="SRI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00419">
        <property type="entry name" value="ADXRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54373">
        <property type="entry name" value="FAD-linked reductases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SWIRM" evidence="10">
        <location>
            <begin position="314"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1458"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1665"/>
            <end position="1710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1465"/>
            <end position="1474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1670"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1686"/>
            <end position="1699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0572419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1804" mass="197160" checksum="95DC717AA9593862" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNP5</accession>
    <name>A0A8T0HNP5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG080900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNP5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9986" checksum="ACA55F7F7152805E" modified="2022-10-12" version="1">MCQNFICNHRLRFCSRFPLHQQSTVSYNTMPPLPCLAFFISAIFFQHINNDHDNLIASLLLTHSLSHYSSIFFSRKINNSIFTIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP22</accession>
    <name>A0A8T0HP22_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG103800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="16646" checksum="58EA193331FF3712" modified="2022-10-12" version="1">MLQPTPRSSINRRASRSTHLLATPQPWLHSRMPLQPPDLLGRLLLDAAATLHTKPRSHNFHTTTRRSSPERPRAAARRLNSPSLRESRSIELLTTSITADAAHTPRPRSLAPSQLQLSLKSPSVLEHTCTCTNMHSLHLLLSTIQLAFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRN9</accession>
    <name>A0A8T0HRN9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG158100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="11910" checksum="9288C6B8D3832745" modified="2022-10-12" version="1">MYGRPGCRHSELAIAGASDSSLEEALRVSTETKNPGEGGSAGGGGLERRTSPTSMSPLRCNHQPSVTPEGIEYCHAFEPYIEIHLQETKRTSSEEFWPSGRIIVTDSDTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUM8</accession>
    <name>A0A8T0HUM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG282900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37659" checksum="4B1781670B14550F" modified="2022-10-12" version="1">MGNCNHKFHITCIAKAALNNKQCVMCRSSISSRFYEMLGLQHVMPPGHEFDWWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTAGNAELDDLSWMPHDYEVEMRAHEIPDAKEREFVCRNFGGHWSIHGNRFFRFPKPEDVVDAGDKRREVERDYGQLDEYKMYDRTPVGRALLLAKLEEAIQHRRTFTEESFKYSDLDYWVIIKKSDDALQKIVCDWRRALRAEDNSSRWSRNRIEKIVQETVAKIEKAKELWNGKNSKKRNRDNPYEDDPEWGEDNRRFLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUW7</accession>
    <name>A0A8T0HUW7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG248100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUW7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005303">
        <property type="entry name" value="MOCOS_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237:SF19">
        <property type="entry name" value="MITOCHONDRIAL AMIDOXIME REDUCING COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14237">
        <property type="entry name" value="MOLYBDOPTERIN COFACTOR SULFURASE MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03476">
        <property type="entry name" value="MOSC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141673">
        <property type="entry name" value="MOSC N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="105"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="30216" checksum="90F935E2FC6B1274" modified="2022-10-12" version="1">MVVKAENGRTITMTRAPKLALVQPSLPAAALRGELVPANATLEINAPGMKALKVPFQRSSQGNIVDVGMPTIFDVQGVDQGPEAAEWFTRYLDMPVRLVRFDPSKQTEKRQAEQAPDGFVTGFQNTGQFLFVSEASLDKVNSYFPKAPFPMNRFRPNIVVRGPPSFEEDKWRQFTIKHMGTQLNFSYAMLRGICKVPTINMDKPDLDNVEPNKTMFSFRSGPHVGLEYEKLKKAYFGSYFVCDSTLSKPSNSKVQVIAVGDNLNVITMKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVJ2</accession>
    <name>A0A8T0HVJ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG284900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="259"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="37711" checksum="263AEC9F3B98B207" modified="2022-10-12" version="1">MENCNHKFHITCIAKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTANDAGMDDLSWMTHDYEVEMRAREIPDAKDREFFCKNFGGHWSIHGNRFFRFPKPEVVVDADGKRREVERDYDQLDEYKMYDRTPIGRALVLAKLEEAIQHRRTFTEESFKYSDLDYWVIIKKSNDALQKIVNDWRRALRAEDNSSRWSRTRIEKIVQETVAKIEKAKELWNGKNSKKHNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITYPSQRRQTRRSNANNGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWZ9</accession>
    <name>A0A8T0HWZ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG302700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11101" checksum="B34789423AED7F47" modified="2022-10-12" version="1">MKTASNMNSATDVMLFWKLQRPIAMQSRIVALSARSADTREANKLSPLSPRPKLIASIKTTMIFDDFCCVNEKRWGSSIAGVICARNRKSTVLPAAGSGVIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZA1</accession>
    <name>A0A8T0HZA1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fe/B12 periplasmic-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G045600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05388">
        <property type="entry name" value="CobB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03130">
        <property type="entry name" value="GATase1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1980">
        <property type="entry name" value="Nitrogenase molybdenum iron protein domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA/CobB_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002204">
        <property type="entry name" value="PRK01077.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873:SF1">
        <property type="entry name" value="COBYRINATE A,C-DIAMIDE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53807">
        <property type="entry name" value="Helical backbone' metal receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51274">
        <property type="entry name" value="GATASE_COBBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="7">
        <location>
            <begin position="741"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0575981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1066" mass="115760" checksum="1FE12C51B62757A3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZS9</accession>
    <name>A0A8T0HZS9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G098700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035857975" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6504" checksum="8D9BE93220A3377B" modified="2022-10-12" version="1">MVCHYRTWVLLLVFVCLKHELKSLSFFGYFRFRPSFSSYNFFRHDGSCLSSVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0L0</accession>
    <name>A0A8T0I0L0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G089400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051105">
        <property type="entry name" value="WWC/KIBRA_Hippo_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14791">
        <property type="entry name" value="BOMB/KIRA PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14791:SF42">
        <property type="entry name" value="F16L1.2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="226"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="298"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="226"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="298"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="309"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="45977" checksum="FCD6E2C927862B18" modified="2022-10-12" version="1">MAVAMEVVWRSSGGDQLQLGSGVMTATVDVMRSSVVSNKKRAWGADAQKLMQVMMGQFSHGEEQTLDLLGSGGGGGSGMGSGNGVDEFLEVDPDQPLPAGWEQCLDLKTGELYYVNKSMGMRRTDDPRKLQRVKLAEAMKVGGVIAPRTPVRPAHEFLASKKEETRLRASTTSSGSSGEDVVTANNNNNNTVVVVAAPPPAATQQLSFSTGKRLWNLQLDDRDRTTISLNKTPGTSWSNSPRAPPFPNSPSSRDESKLDINLNLSPTRSRPSPSPSPSPLSHAQTVCNLEMVQQALKRTEKAMGKREATTTITTTTFPPPLSTSSSFSSLAEPSWSRSSPSTSSSSTSKFLSHDVMIDIPPPRVNSEAESSGAGPLELVMGKCKRCSMMVMVNKKDPKCPGCESVEVGFVSFGTPALPPPKRPRVGPMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2L2</accession>
    <name>A0A8T0I2L2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G108500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2L2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="443"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="483"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="528"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="572"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0576798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="603" mass="67209" checksum="234378B641C21EBB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I487</accession>
    <name>A0A8T0I487_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_5G191600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Plastid</location>
            <location evidence="1 8">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I487"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000009">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="3 8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5 8" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0577916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="37243" checksum="8280FFF41A8BA12C" modified="2022-10-12" version="1">MAASISGSVLRNPCQSGFAHGSKFENSFKGDEVKLNCGFITRRKGKHSQCRAAWQELAGVVVFSALPFTIVKGIANSSIGEQLQQRMLKTKTAAQEAAGEAREAQSNARNASMWYREGRPKWLGPVPYDYPDHLQGEAPGDYGFDILGLARNTTDFEKYFNFEILHARWAMLAALGVVIPELLDRFGGVQFSEPVWWKVGYAKFQGDTLDYLGIPGLHIAGAQGVLVIAFCQVILMLGPEYARYCGIEALEPLGIFLPGDVNYPGGALFDPLGLTKDAAAFEDLKVKEMKNGRLAMVAWLGFYVQALVTQKGPIDNLFDFIEDPLHQNLFAYIFSGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4M4</accession>
    <name>A0A8T0I4M4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G160900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4M4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005134">
        <property type="entry name" value="UPF0114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721">
        <property type="entry name" value="OS06G0710300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721:SF4">
        <property type="entry name" value="OS06G0710300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03350">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="36143" checksum="F7F1B9359C80EEF3" modified="2022-10-12" version="1">MRILAMDTIAGVSMGYLQSGRAISSTGISCVLRCGEASQRCDVILSTACTSGRQSIVKIDGRGRLNYRWGGSSRFCNPRVFSDRLGGRLPLERVALQIRASGENTLPLQVDTNGVATLEPYLDVSPSENNGSLSSRKEDGRERLEALIERVIFNCRFLTLMAVAGSLAGSVLCFLKGSLYVTQSFFEYFQAAWQGLGTSQVVFLLVEAVDVYLMGTVMLIFGMGLYELFVSTLDVAGDGCEEVRNPVCGSNLFGLFRMRERPKWLEIRSLDELKTKLGHVIVMILLVGMFEKSKKVPISSGLDLLCFSASILLSSGCLFLLSKLHSSTEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5B3</accession>
    <name>A0A8T0I5B3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein TIC 40, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Translocon at the inner envelope membrane of chloroplasts 40</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_4G039200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in protein precursor import into chloroplasts. Part of the motor complex consisting of a co-chaperone (TIC40) and a chaperone (HSP93) associated with the import channel (TIC110). Causes the release of bound transit peptides from TIC110 and stimulates ATP hydrolysis by HSP93. Involved in reinsertion of proteins from the chloroplast stroma into the inner membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Plastid</location>
            <location evidence="12">Chloroplast inner membrane</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5B3"/>
    <dbReference type="OrthoDB" id="533763at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009706">
        <property type="term" value="C:chloroplast inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009658">
        <property type="term" value="P:chloroplast organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000008">
        <property type="entry name" value="Protein TIC 40, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.2020.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038108">
        <property type="entry name" value="RPN13_DEUBAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47296">
        <property type="entry name" value="PROTEIN TIC 40, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47296:SF1">
        <property type="entry name" value="PROTEIN TIC 40, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1001">Plastid inner membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="STI1" evidence="16">
        <location>
            <begin position="325"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="16">
        <location>
            <begin position="401"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="189"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="15">
        <location>
            <begin position="189"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="251"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00070821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00082202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0578652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="465" mass="49282" checksum="3A9980A215C84FF1" modified="2022-10-12" version="1">MAMESRLLHHASPLVSNARAGAGEGRSCGNQGFRLSSSQRFMRGVAVRPAQGVSVGSRRERRGARSVVVAARRPVQEQQEYVEAKNDTAEYVESTAEAHGSGSSYIGSPLLWIGVGVGLSALFSFGANSVKRYAMQQMLKSMTGGAGGPGASPFGGPGANPFGAPGANPFGAPGANPFAGMPMPPPGAGFPFPMPPTGTPPSPVSAAAAAPPVDVAPSNVASSQPSVKSESSTTSAESRKTAFTDVNASEILEREQQAAARFRDQAPSASEPTRSFFADSEVVDSRGGSNSGAGAGPSSNESWTNAGKGKQPVFTVDQLEKMMEDPTVQKMVYPYLPEEMRNPTTFKWMMQNPQYRQQLQDMLNGMGGDGAFDNRMSDMLKNFDLNSTEVKQQFEQIGLTPEEVVAKIMANPDVAVAFQNPKVQAAIMDCSTNPLNITKYQNDKEVMDVFNKISELFPGMTGSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6J4</accession>
    <name>A0A8T0I6J4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G071600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6J4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000003">
        <property type="entry name" value="60S ribosomal protein L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00499">
        <property type="entry name" value="Ribosomal_eL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001380">
        <property type="entry name" value="Ribosomal_eL13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018256">
        <property type="entry name" value="Ribosomal_eL13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11722:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01294">
        <property type="entry name" value="Ribosomal_L13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01104">
        <property type="entry name" value="RIBOSOMAL_L13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0579082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="207" mass="23664" checksum="7D36EE3800297BE3" modified="2022-10-12" version="1">MVKHNNVIPNGHFKKDWQSYVRTWFNQPARKKRRRTVRQKKAVAVFPRPTAGPLRPVVHSQTLKYNAKIRAGRGFTLEELKAAGISKKLAPTIGIAVDHRRKNRCLESLQENVNRLNTYRAKLVVFPRRSRKTKTGDASAEDLSSVTQLSGAVLPIIKPRPSAEIVSITDEMKAQKGFYKLRQERMNERLVGVRKKKAEAAEKEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9C4</accession>
    <name>A0A8T0I9C4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Mechanosensitive ion channel MscS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G092600</name>
        <name evidence="7" type="ORF">KC19_8G171700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9C4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF27">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="6">
        <location>
            <begin position="303"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="54302" checksum="DCEE332A25EEDBB3" modified="2022-10-12" version="1">MASLLHASAALSAKRRETLIPNASLKTLLQCSSVSSFSGTTLENLSWNTKPCTRSRTSGRSGVARASKLSPVLEKRVRIGEHCLDNVSNYIFHQLRKPFAKYIPDDWDPLDFLPVNIQSNLQKSEALATLVVREILVFVMVYIVYEKVEVLCRWLYGMFTRKQRNGQPIDDEAYAESPFRAARQPVRSLVLIWASTRLLWITSVLWKMQAVITPAVIYKLRAVSIVCTISWFFFRWKRLYVEHLIVQKPLDESRILVIDKLLSLAMYGLAAACIAEVLGLALNSLLAVGGVSGLAVGLAAKEVVGNMFGGASLFISRPFVIGEKIKVDIKAGSVSGRVQDIGFMQTKVQGFDGVPVLVPNQAFTSQVITNFSRAKTKVLEASFQLNNRHIFLVHDITTKVQKYLSSQPSVESMKATPICYLQSMEKDGPVIALSCVIKAVGGEVFYRYQQEILIQVAHIITDILGPDSPFTPIKVPNSDTSVVSSEGLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAF3</accession>
    <name>A0A8T0IAF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G131500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17351">
        <property type="entry name" value="MFS_NPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="OLIGOPEPTIDE TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="436"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="473"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="512"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="558"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="601"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="683"/>
            <end position="776"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="776" mass="85602" checksum="FB93224D4BC3B7D5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBY5</accession>
    <name>A0A8T0IBY5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">U6 snRNA-associated Sm-like protein LSm1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">LSM1</name>
        <name evidence="10" type="ORF">KC19_4G178300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay. LSM1A and LSM1B are essential for the formation of the cytoplasmic LSM1-LSM7 complex which regulates developmental gene expression by the decapping of specific development-related transcripts. Required for P-body formation during heat stress.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990726">
        <property type="term" value="C:Lsm1-7-Pat1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009631">
        <property type="term" value="P:cold acclimation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000290">
        <property type="term" value="P:deadenylation-dependent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042538">
        <property type="term" value="P:hyperosmotic salinity response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01728">
        <property type="entry name" value="LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000029">
        <property type="entry name" value="U6 snRNA-associated Sm-like protein LSm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034104">
        <property type="entry name" value="Lsm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044642">
        <property type="entry name" value="PTHR15588"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588">
        <property type="entry name" value="LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15588:SF8">
        <property type="entry name" value="U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="9">
        <location>
            <begin position="11"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="107"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0580505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14443" checksum="7C1CC319DF2C97CF" modified="2022-10-12" version="1">MSWAGPDNFPATSTSLADNLDKKLLVILRDGRRIIGILRSFDQFANVVLEGAVERSIVEELYCDLPLGLYIIRGENVVLIGELDLEKEELPAFMVAVTHAEIKQAQKVEKDGEEHNKVDHKVQNVTTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC76</accession>
    <name>A0A8T0IC76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G146300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="10463" checksum="B6A5064F07085F00" modified="2022-10-12" version="1">MSGKTSTIITAAFCNTKVAPQNTAQESVALLILTRRTAHQCQYSQSASTNSTSPSKKTPLSRICGSNPMTHQHLLKAITALHSKKKTNFYSLNPNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICY6</accession>
    <name>A0A8T0ICY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SBP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G200200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1100.10:FF:000001">
        <property type="entry name" value="Squamosa promoter-binding-like protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1100.10">
        <property type="entry name" value="Transcription factor, SBP-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044817">
        <property type="entry name" value="SBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004333">
        <property type="entry name" value="SBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036893">
        <property type="entry name" value="SBP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251:SF169">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03110">
        <property type="entry name" value="SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103612">
        <property type="entry name" value="SBT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51141">
        <property type="entry name" value="ZF_SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SBP-type" evidence="9">
        <location>
            <begin position="219"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="287"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="547"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="315"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="342"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="548"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="619"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0580797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="665" mass="71182" checksum="8968B1D52AD5C546" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDP4</accession>
    <name>A0A8T0IDP4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G214400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="241" mass="27188" checksum="A4B34E5AE038CF2F" modified="2022-10-12" version="1">MDRDHIPIMEALSFGQHCKITRVDITTGIFDCPKLLYASDGEEDDNLPNAHENDNLPNAHEDDNLPNVQGENPEHEVVGPLGIVEPFQSLEQIFNTQFHEQSVDRVRSLMAQSDEGNPLLKEEVVDLPEKLSNVEWIEYLVKKGPTILTSPKNRMQTSTILRKLSGELMVLPPGNNAEVQGDWRDRSQWWRYLSALVSELMMVEDGCSSEVRDAGLFVLSTFEYPALLELMAQEIAQTLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG68</accession>
    <name>A0A8T0IG68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G084200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF268">
        <property type="entry name" value="FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="EGF-like" evidence="6">
        <location>
            <begin position="99"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="122"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="768" mass="87491" checksum="44F9CC244961613E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGS9</accession>
    <name>A0A8T0IGS9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G269900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070939">
        <property type="term" value="C:Dsl1/NZR complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060628">
        <property type="term" value="P:regulation of ER to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007528">
        <property type="entry name" value="RINT1_Tip20"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520:SF0">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13520">
        <property type="entry name" value="RAD50-INTERACTING PROTEIN 1 RINT-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04437">
        <property type="entry name" value="RINT1_TIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51386">
        <property type="entry name" value="RINT1_TIP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="812" mass="91192" checksum="2671970548BA70AF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHL8</accession>
    <name>A0A8T0IHL8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7748 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G022800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHL8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056650">
        <property type="entry name" value="DUF7748"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24928">
        <property type="entry name" value="DUF7748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7748" evidence="2">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="13861" checksum="5E7EC1119D1E44D8" modified="2022-10-12" version="1">MVKTAIINKSGSTLLVKEGSGGIFRSVFNIPEGERRNLSVDTNATYRQFLLIIKPDFLHILSNDDCAEFDSVTVNVVDGKFKVESTPRALKSNSGAPPPPAPPPPRESFGKRVRRSIASYFRDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK02</accession>
    <name>A0A8T0IK02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G113900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK02"/>
    <dbReference type="OrthoDB" id="6082470at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02900">
        <property type="entry name" value="Macro_Appr_pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="entry name" value="Leucine Aminopeptidase, subunit E, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028071">
        <property type="entry name" value="Macro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14519">
        <property type="entry name" value="Macro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="Macro domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="51"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="32299" checksum="C8D7DAF73AFD8140" modified="2022-10-12" version="1">MAHSMEIDNGSAAEFRVQNSASSSECLKIVFVDLQQKLVSAWQEEITKELPSTLLEQKSRTISIAACQANFQDFLQSTQVDCMVSPANSFGLMDGGLDLAISKYYGGVANLVPVVRAALDDEWCGQQNVGTCLLVDAQKLVQFARQGEQAKNVPRYIAHVPTMRVPKVLHPDDDIAYRCTWALLTAIRKHNIEVAKQGQSSAGHERINSVLCAGFGTGAGQFPVDECARQMVLAVKHFAEKTSKSSSEEGELGGSSGLMTLWDEAEKIEDAVCSFAHEMKSGETPTSSSIFEKVFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK77</accession>
    <name>A0A8T0IK77_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G120800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000126">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF4">
        <property type="entry name" value="OS09G0441700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0583247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="539" mass="60908" checksum="5DBE325E8D5B2845" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKL1</accession>
    <name>A0A8T0IKL1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G146800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052623">
        <property type="entry name" value="DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056497">
        <property type="entry name" value="HEAT_DAAF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057978">
        <property type="entry name" value="TPR_DAAF5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216">
        <property type="entry name" value="DYNEIN ASSEMBLY FACTOR 5, AXONEMAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16216:SF2">
        <property type="entry name" value="DYNEIN AXONEMAL ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24573">
        <property type="entry name" value="HEAT_DAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25757">
        <property type="entry name" value="TPR_DNAAF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 5 TPR repeats" evidence="4">
        <location>
            <begin position="33"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein axonemal assembly factor 5 HEAT-repeat" evidence="3">
        <location>
            <begin position="673"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="505"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="351"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="510"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1207" mass="135334" checksum="B9AD1D670369C032" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL31</accession>
    <name>A0A8T0IL31_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G151900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060962">
        <property type="term" value="P:regulation of ribosomal protein gene transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22701">
        <property type="entry name" value="FHA_FKH1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000014">
        <property type="entry name" value="FHA domain-containing protein FHA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045178">
        <property type="entry name" value="Fhl1/FHA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21712:SF29">
        <property type="entry name" value="PRE-RRNA-PROCESSING PROTEIN FHL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="4">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="118"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="326" mass="35761" checksum="97ED1EB491AD37BB" modified="2022-10-12" version="1">MGEMEAGFAKLQGEDFEYYMQTYSIVLGRNSKKSSVDVDLAGLGGGMNISRQHARILYDFERRRFVLEVLGKNGCYVEGVLHMPGTSPVKLDSQDLLQIGEKRFYFLLPAKKIARSVAAVSSPNNPRKRAAGGAPGRAGPGASLVLAPGPTPAKKVRGQGKNGPAPGGGVGVGGGGGVVRERKQASTSPWMAQQEVEPSPNAGSTTRVRDGYRYEDDEADEQYEEREVVRIILEKLQSQYHPGEWMAVSKLHADILDHFQSRNMSPQFMHIMGVDEDGNEIDGKGNGRAWSGLVNLLKRYPRHFVINTKLKGGIRVEYVSLYPEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILQ7</accession>
    <name>A0A8T0ILQ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G192100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12143" checksum="EFCECD39993F553C" modified="2022-10-12" version="1">MNDHPSAAAVSLRISVSAISTSFMNSFFLTHQLRYFNKILSYMERFKFLLPINQGVFVLKIYMLFDFVCKSCRHSVCIRRKCHCPSGSRVFWTCDVTYTGLQLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILS5</accession>
    <name>A0A8T0ILS5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G230400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="195" mass="23670" checksum="B2C9816156975C8D" modified="2022-10-12" version="1">MEVEYLIDVDKELRNYVRPGGPYKLTRYAVVDKDVHVCADYADWYYDPELRYVKDYDIKGYRKRRIQRWLSEVLPIHEDERFDRYLVRCHAEALKELTLMNQEYIEYQNTFHHIVDKWVSVLHLGMLFKRKNMGKSCDVNESALIIKLLREQCEMLYHKTKIIFFEESTEKRDRNVVPKQHWILHPRNLCGDSPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMY8</accession>
    <name>A0A8T0IMY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="29">Dynein heavy chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">KC19_3G193200</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.2620:FF:000001">
        <property type="entry name" value="Cytoplasmic dynein heavy chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.180.20:FF:000003">
        <property type="entry name" value="Dynein heavy chain 12, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000001">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.490.20:FF:000008">
        <property type="entry name" value="dynein heavy chain 2, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000063">
        <property type="entry name" value="dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:003748">
        <property type="entry name" value="Dynein heavy chain 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.720:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.20:FF:000006">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000362">
        <property type="entry name" value="Dynein, axonemal, heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001145">
        <property type="entry name" value="Putative dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.920.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.100">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.180.20">
        <property type="entry name" value="Dynein heavy chain, N-terminal domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035699">
        <property type="entry name" value="AAA_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035706">
        <property type="entry name" value="AAA_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041589">
        <property type="entry name" value="DNAH3_AAA_lid_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042222">
        <property type="entry name" value="Dynein_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043157">
        <property type="entry name" value="Dynein_AAA1S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041466">
        <property type="entry name" value="Dynein_AAA5_ext"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041228">
        <property type="entry name" value="Dynein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043160">
        <property type="entry name" value="Dynein_C_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024743">
        <property type="entry name" value="Dynein_HC_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024317">
        <property type="entry name" value="Dynein_heavy_chain_D4_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004273">
        <property type="entry name" value="Dynein_heavy_D6_P-loop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013602">
        <property type="entry name" value="Dynein_heavy_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042228">
        <property type="entry name" value="Dynein_linker_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12774">
        <property type="entry name" value="AAA_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12775">
        <property type="entry name" value="AAA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12780">
        <property type="entry name" value="AAA_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12781">
        <property type="entry name" value="AAA_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17857">
        <property type="entry name" value="AAA_lid_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08393">
        <property type="entry name" value="DHC_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17852">
        <property type="entry name" value="Dynein_AAA_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18199">
        <property type="entry name" value="Dynein_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03028">
        <property type="entry name" value="Dynein_heavy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12777">
        <property type="entry name" value="MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0966">Cell projection</keyword>
    <keyword evidence="12" id="KW-0969">Cilium</keyword>
    <keyword evidence="7" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="11 16" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="10" id="KW-0243">Dynein</keyword>
    <keyword evidence="9" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="13" id="KW-0505">Motor protein</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein heavy chain linker" evidence="18">
        <location>
            <begin position="115"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain hydrolytic ATP-binding dynein motor region" evidence="19">
        <location>
            <begin position="651"/>
            <end position="977"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA 5 extension" evidence="23">
        <location>
            <begin position="1153"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain 3 AAA+ lid" evidence="24">
        <location>
            <begin position="1497"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA module D4" evidence="21">
        <location>
            <begin position="1645"/>
            <end position="1904"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain coiled coil stalk" evidence="20">
        <location>
            <begin position="1918"/>
            <end position="2248"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain ATP-binding dynein motor region" evidence="22">
        <location>
            <begin position="2276"/>
            <end position="2496"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain region D6 P-loop" evidence="17">
        <location>
            <begin position="2747"/>
            <end position="2864"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="25">
        <location>
            <begin position="2896"/>
            <end position="3034"/>
        </location>
    </feature>
    <feature type="domain" description="Dynein heavy chain C-terminal" evidence="26">
        <location>
            <begin position="3041"/>
            <end position="3349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="16">
        <location>
            <begin position="2132"/>
            <end position="2187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF03028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF08393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF12774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF12777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF12780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF12781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="Pfam" id="PF17852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="Pfam" id="PF17857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="Pfam" id="PF18199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAG0584206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="29">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3352" mass="380746" checksum="6A5BA74A2DB1DFF1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ32</accession>
    <name>A0A8T0IQ32_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G042800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35506">
        <property type="entry name" value="OS02G0135600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35506:SF1">
        <property type="entry name" value="OS02G0135600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="307" mass="33327" checksum="76F8278EB6C25B32" modified="2022-10-12" version="1">MADKPARALVIYGDGIMPAVKTHHEHLHRLAASGSCGFLALRALPEASEGEREVVELAQLLDVYDIYTEKARKEDSAGEVTEDGSFKTLAERFMGMKSTFMTNSKAALALSKRAGFGGSSLEEFGVDSEASATASRVLGLLGFDESTSMKDPANELVFVHLDAKSGSSAESGAEFLDSLVGCVQESSKEGSLAYGRLFLVVVLGYGDAQASGESVPSFRDDGELPSVLAALRPRQSYTMKAGKPVEGLREEYPLLAVYNQVAVTRRDEVQRFLFEDFHKRAGNLVMLADRFLYEVAFKLWKAPKYGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ61</accession>
    <name>A0A8T0IQ61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pectate lyase</fullName>
            <ecNumber evidence="3 8">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G045700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion. Required for its activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="3 8"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018082">
        <property type="entry name" value="AmbAllergen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF187">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00807">
        <property type="entry name" value="AMBALLERGEN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035959551" description="Pectate lyase" evidence="8">
        <location>
            <begin position="35"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="9">
        <location>
            <begin position="231"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0585870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="56108" checksum="88B310678B56969C" modified="2022-10-12" version="1">MAYSCRMACTSAHHLLLLAFLLFILQHSHMPCEARPTYLNNIIGTNDATNPTSSEVLLQEAKTVTNLRAFFQSIVDLLHFQNATQTAGHKNQLDFEKESELEAPEKIIDTSGAGFIYNAENQVEQEDANTDEAAAEEPHLLMPFQKPASTPGNCKTGNYIDDCWRCDANWQDRRQALASCAIGFGQYAYGGKDGKIYVVTSNNDDIRSPSPGTLRYGVTRSEPLWITFAKDMTIELKGELIVSSYKTIDGRGAEIHIVGTSQITIEGVSNVIVHGIHVHDILTSGPHHILTAPNLRTFRGSSDGDAIHIKGSSNVWVDHCFLAKATDGLVDGTKNSTNITVSNSYFENHNKVMLFGASPKDDYDRNMQITVAFNRFGPGLTQRLPRCRYGSCHVANNFYTSGWGLYAIGGSEDPTFLSQCNRFVAPDATNRKEVTSRIDDDGPTFGGWQKWDWVSTGDSFANGAFFTGSGVQNASASNYDRARSFVPRHASWVAAMTEDAGPLNCVPKSSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQQ1</accession>
    <name>A0A8T0IQQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">GPI ethanolamine phosphate transferase 1</fullName>
            <ecNumber evidence="12">2.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G006200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Endoplasmic reticulum membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.-.-.-" evidence="12"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQQ1"/>
    <dbReference type="OrthoDB" id="2748310at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051377">
        <property type="term" value="F:mannose-ethanolamine phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16020">
        <property type="entry name" value="GPI_EPT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.720.10:FF:000015">
        <property type="entry name" value="GPI ethanolamine phosphate transferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="entry name" value="Alkaline Phosphatase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007070">
        <property type="entry name" value="GPI_EtnP_transferase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017852">
        <property type="entry name" value="GPI_EtnP_transferase_1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037671">
        <property type="entry name" value="PIGN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250:SF0">
        <property type="entry name" value="GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12250">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL GLYCAN, CLASS N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04987">
        <property type="entry name" value="PigN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="Alkaline phosphatase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 12" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="452"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="526"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="588"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="616"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="641"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="684"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="716"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="741"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="766"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="827"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="866"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="899"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="932"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase N-terminal" evidence="13">
        <location>
            <begin position="157"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="GPI ethanolamine phosphate transferase 1 C-terminal" evidence="14">
        <location>
            <begin position="442"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU367138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0585367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="983" mass="110211" checksum="BD25D248F4916203" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU01</accession>
    <name>A0A8T0IU01_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FYVE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G100900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG0586575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome 2"/>
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        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:late endosome membrane"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070676">
        <property type="term" value="P:intralumenal vesicle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036258">
        <property type="term" value="P:multivesicular body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc finger, FYVE-type, endofin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FREE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002404">
        <property type="entry name" value="IRS_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000306">
        <property type="entry name" value="Znf_FYVE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017455">
        <property type="entry name" value="Znf_FYVE-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46977">
        <property type="entry name" value="PROTEIN FREE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46977:SF1">
        <property type="entry name" value="PROTEIN FREE1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="IRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00064">
        <property type="entry name" value="FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ZF_FYVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FYVE-type" evidence="6">
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            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
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            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
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        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
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            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="127"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="163"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="559"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="569"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0586575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="621" mass="64789" checksum="236F809183D50F38" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUN4</accession>
    <name>A0A8T0IUN4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G118900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038956">
        <property type="entry name" value="LEA_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000389">
        <property type="entry name" value="Small_hydrophilic_seed_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671">
        <property type="entry name" value="EM-LIKE PROTEIN GEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671:SF19">
        <property type="entry name" value="EMBRYONIC ABUNDANT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00477">
        <property type="entry name" value="LEA_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="15686" checksum="D38A61A93FBCC67F" modified="2022-10-12" version="1">MATRADLDTRAHEGEVVPGGTGGHSLEAQEHLAEGRHKGGETRARQLGHEGFVEMGKKGGLASHGADPYQAAAKQGVHIDEHKFMNDSSIEELDKRALNGEVIVPGGTGGHSLEAQKHLAEGRHKGGVTRAHQLGHEGYVEIGRKGGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV62</accession>
    <name>A0A8T0IV62_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MD-2-related lipid-recognition domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G076900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NPC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003172">
        <property type="entry name" value="ML_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039670">
        <property type="entry name" value="NPC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306">
        <property type="entry name" value="NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11306:SF0">
        <property type="entry name" value="PHOSPHATIDYLGLYCEROL_PHOSPHATIDYLINOSITOL TRANSFER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02221">
        <property type="entry name" value="E1_DerP2_DerF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00737">
        <property type="entry name" value="ML"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035892098" description="MD-2-related lipid-recognition domain-containing protein" evidence="7">
        <location>
            <begin position="25"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="MD-2-related lipid-recognition" evidence="8">
        <location>
            <begin position="31"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0586263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19368" checksum="DBAE7852F6FA83B5" modified="2022-10-12" version="1">MAQFVSSRTAVLLLVASLAVLATAAPKPSDWHVCDRHANYDILVKNVTINPDPVVSGEEMTFMVPAYTAKEITGGSVIVSVSFHGVTVHTERNDICEKAACPIAPGEFVLKNTEVLPGITPPGSYRIKLQFVGEEGEQLACANINFSIIWSASIAETLEGFNPIQLHKKIAKMQAPVAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXH9</accession>
    <name>A0A8T0IXH9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">argininosuccinate synthase</fullName>
            <ecNumber evidence="3">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G200900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000053">
        <property type="term" value="P:argininosuccinate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:L-arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000050">
        <property type="term" value="P:urea cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="ASS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000019">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1260.10:FF:000007">
        <property type="entry name" value="Argininosuccinate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="entry name" value="Argininosuccinate synthetase, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.470">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048268">
        <property type="entry name" value="Arginosuc_syn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048267">
        <property type="entry name" value="Arginosuc_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001770">
        <property type="entry name" value="PRK00509.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587:SF2">
        <property type="entry name" value="ARGININOSUCCINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20979">
        <property type="entry name" value="Arginosuc_syn_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="Argininosuccinate synthetase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginosuccinate synthase-like N-terminal" evidence="10">
        <location>
            <begin position="88"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Arginosuccinate synthase C-terminal" evidence="11">
        <location>
            <begin position="259"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF20979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0587915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="485" mass="52765" checksum="6DCEA811AC30B558" modified="2022-10-12" version="1">MATTLAQSMACPKAVVVQAGVSLSESRCTTAICGASTNRMWGTSLSMTPAVSGLRKVSQAKGIRAAIGSVDVKTTEETKGGIRGKLNKVVLAYSGGLDTSVIVPWLRENYGCEVVCFTADVGQGVGETEGLEAKAKASGASELVIADLREEFVRDYIFPCLRAGAVYERKYLLGTSMARPIIAKAMVDVAKACGADAVSHGCTGKGNDQVRFELTFFALNPKLAVVAPWREWDIKGREDAIEYAKKHNVPVVATKKSIYSRDRNLWHISHEGDILEDPANEPAKDMFVMSVDPEDAPDTPEYLTIQIEKGLPVGFNGKKLSPATLLEELNEIGGKHGIGRIDMVENRLVGMKSRGVYETPGGTILTSACRELEALTLDRESMQMKDMLALKYAELVYAGRWFDPLRESMDAFMEKMTETTTGEVTLKLYKGSVNVASRSSPNSLYRQDISSFEEGSGIYDQADAAGFIRLYGLPTRVRAMQQHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J085</accession>
    <name>A0A8T0J085_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Remorin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G249900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the remorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J085"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005516">
        <property type="entry name" value="Remorin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31471">
        <property type="entry name" value="OS02G0116800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31471:SF1">
        <property type="entry name" value="OS12G0613600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03763">
        <property type="entry name" value="Remorin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Remorin C-terminal" evidence="4">
        <location>
            <begin position="541"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="130"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="414"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="574"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="145"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="421"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="450"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0588539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="651" mass="70106" checksum="9B1DBFE2E645286A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1S9</accession>
    <name>A0A8T0J1S9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G290500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1S9"/>
    <dbReference type="OrthoDB" id="1878800at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF1">
        <property type="entry name" value="OS08G0103600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="608"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="776"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="568"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="838" mass="93484" checksum="3E2ACF72AB7387AA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2J0</accession>
    <name>A0A8T0J2J0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Pex N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G015100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pex2/pex10/pex12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2J0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017375">
        <property type="entry name" value="PEX12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006845">
        <property type="entry name" value="Pex_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888:SF0">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12888">
        <property type="entry name" value="PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04757">
        <property type="entry name" value="Pex2_Pex12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Pex N-terminal" evidence="13">
        <location>
            <begin position="21"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0589349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9874" checksum="AF1C6BB3C6B5644D" modified="2022-10-12" version="1">MLMQVGGEGTRPTFFEMSATEHLPTSLRDALLYFLGVMAQRRPVLHRVLDYSDEGYAALMLLLELHSLKTLDASFPESLYGLRQTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3G4</accession>
    <name>A0A8T0J3G4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G038300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="11259" checksum="ABD8D8B170AFF881" modified="2022-10-12" version="1">MLQVTEEASFNLKEAMKMLQELDSSDVFGQNQETRRKVCGKKAMSRVDRALRHLASHNSHMEELKLRMHVMREKLEIAQGTQTEVLQRMDAVANEMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3U4</accession>
    <name>A0A8T0J3U4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G111500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3U4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="14855" checksum="14A03A434EBCCA33" modified="2022-10-12" version="1">MPGTKRDLKGRTQVTRFCSKQYASQLSSTKQLILPSTYFDTPVRRRSERHAYLPKHCHVLCSDVLQLVLGNLCFRVAPTSSHLLQHTHSLPSDSYHTTIPTPNVLALPLSLPPSLPLSPSLSLSPFTERNEPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J485</accession>
    <name>A0A8T0J485_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lachrymatory factor synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G031600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J485"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07821">
        <property type="entry name" value="PYR_PYL_RCAR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053249">
        <property type="entry name" value="LFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33789:SF5">
        <property type="entry name" value="BET V I_MAJOR LATEX PROTEIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33789">
        <property type="entry name" value="LACHRYMATORY-FACTOR SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="181" mass="19777" checksum="925C2CEFDCC38B35" modified="2022-10-12" version="1">MAAEAAATATPADADRAMVESVVPAPMPWNGVVEKTISAPLEKVWDVASDFLGFPNVLTIEPVEGENRVAGCTRKVTNLPGRTDTDSAQWAKQKLVEINPAEHVFSYEFLENNTGVDPGYYSTFQAKKEEGGKTFVRWAFRFSPSQVGSDRFVPFIMKGTDLYVQELEKLANAASAVCVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5W3</accession>
    <name>A0A8T0J5W3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G165000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5W3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009798">
        <property type="entry name" value="Wun1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33703">
        <property type="entry name" value="OS07G0691300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33703:SF1">
        <property type="entry name" value="WOUND-INDUCED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07107">
        <property type="entry name" value="WI12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="21064" checksum="DA5C3C2DD6FE4DE4" modified="2022-10-12" version="1">MSQENSCNSSQGSNSLEVFPTSALETDDHERKSVPSTCTLLVDVPKNNECILRCFYNALAMGNTGLLSHLLAEDLDLWFHGPRCHQHMSKLLTGVTSHRSVALTPSSILATRNFVIAEGVCGEVASWVHIWTVEEGKLIQLREFWNTAVWVSFIACVASDSGTLLEPPSPIFWTSKLWHAVGGTKPGLLVTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J759</accession>
    <name>A0A8T0J759_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G198100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tetraspanin (TM4SF) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009734">
        <property type="term" value="P:auxin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044991">
        <property type="entry name" value="TET_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018499">
        <property type="entry name" value="Tetraspanin/Peripherin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32191">
        <property type="entry name" value="TETRASPANIN-8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00335">
        <property type="entry name" value="Tetraspanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0591740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="280" mass="30300" checksum="72BA34BBAF7911D5" modified="2022-10-12" version="1">MGDGGDDGGFSKSDREISHGAHFVKGINVLALLAALALIALGIWLATRPGDCEKYATVPVFLIGAGFLLVAALGLFGTWFLYLPILYTYLVLTFVILVGFLALSIFIFVVTQKGGGYNVPGQSFKEYNVNDYSDYVQHRLNKVSNWNHLKAVIGASDTCATFDQISPVDYPYSNLNSLQSGCCRPPAECGYTMTGNGTFSTTRVPLSDNPDCTSYSNDDSIKCYDCDSCKGGVAQNLKRTGKIAGIVTLVIFVLLVGILVVACHVGHRVARASWRRVERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8S1</accession>
    <name>A0A8T0J8S1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G170900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16561" checksum="A32FBFACD2274EB3" modified="2022-10-12" version="1">MCHGRKQGRMWAKCGRRQVQGKSMAAKSGKSKVRRVSKPKRMDGWPTSVDACGLCAAQDTLAGRQAVGVEGEAAAAAVPLLLLLLLLLMPGPGENWWVLELGLGAGGAEARCEERHRGAVVGFFILRCRFRAARQVERRTPLRRWTRQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAC4</accession>
    <name>A0A8T0JAC4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G209200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="30" mass="3660" checksum="82E40E617C33AD86" modified="2022-10-12" version="1">MRRNFQLLKGPERGVWWRGDLDLMVNQRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAR3</accession>
    <name>A0A8T0JAR3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G246000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12927" checksum="E6E8D0960D0BAC9D" modified="2022-10-12" version="1">MFLFGSVWYFAFRGLGWLYRVLCVVRIPVVAYAVCWKGEQCACKCVEGWMLVLCTGSSKQVWGGLGVFGGWEWHGEVVAKAKAGEELQVRKVVWTLLLIYVLWVSHICAHHYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAZ1</accession>
    <name>A0A8T0JAZ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G304000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043812">
        <property type="term" value="F:phosphatidylinositol-4-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046856">
        <property type="term" value="P:phosphatidylinositol dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002013">
        <property type="entry name" value="SAC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662">
        <property type="entry name" value="PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45662:SF2">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02383">
        <property type="entry name" value="Syja_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50275">
        <property type="entry name" value="SAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAC" evidence="1">
        <location>
            <begin position="118"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="580" mass="64602" checksum="FE8D703B6B34B2B9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCH2</accession>
    <name>A0A8T0JCH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G260000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCH2"/>
    <dbReference type="OrthoDB" id="552049at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="56"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="17819" checksum="AE218CDE6B5228F3" modified="2022-10-12" version="1">MITGKAIPICRTAFQGESLMSSSPKSVGALSSSCSPRRKSGYGLVTMAYAGASVRDPHSTLGVSPGASKHEIKKAYRRLALKFHPDVCDGNHCTTNFQQINFAYETLLSMTTPQFGEFEDDLSDNLEGFMGVGDDSWEDWEEWMGWEGAGTRDYSDHINYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCU2</accession>
    <name>A0A8T0JCU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7734 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G284900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCU2"/>
    <dbReference type="OrthoDB" id="2018366at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056636">
        <property type="entry name" value="DUF7734"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36729">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36729:SF2">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24869">
        <property type="entry name" value="DUF7734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7734" evidence="2">
        <location>
            <begin position="93"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="20253" checksum="2D6D585671DEA7EB" modified="2022-10-12" version="1">MAMATSLHHCALPPPPMPGSLSPRHHRPPGLAIRNSVFPTIQARFVYSSSQTGAWKSGCRRAGSLAAATGDEPAATAEAGSLQDLQDLPFDITRLEQYTEKVKNEVLRVHAVVDGEEDQVIVFKGFSSSLMRPTAYDPAEPVLPPSATIRAIDRIRGPFNPAKVLLIKGGKGLSWQQFETLLEEKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDV5</accession>
    <name>A0A8T0JDV5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G310400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11308" checksum="CB9684EB75F651A3" modified="2022-10-12" version="1">MSSRNATSFSTTSGGQSGWFCRSFAYASVKASTLSADARSRSSASGRIRLSTLAGVIISRKNSPSTSSSTSNLFKVSSLMCPFWVRRRSTYRTIVVSRHASANLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3Q3</accession>
    <name>A0A8T0G3Q3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein CDI-like</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G049200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3Q3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35105">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35105:SF2">
        <property type="entry name" value="PROTEIN CDI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="40065" checksum="3F5DE0123EB5CD14" modified="2022-10-12" version="1">MPNQETCTTVPGSTVKVPSVRHLSMRDASGFSSLCRSRALDPTLKNSSPGPGVHIVSPQLLQSFSTCTEPSTALFSVDSMQLAPSYWKEFSPCDPQSEGRRVKKCSPVITRSGHSLEKIRVYVGFDSREELAYEVCRHSLLKHATVSLEIIPLKLQNLTKEGIYTRPRDPTESTEFSFTRFLTPFLAGFESWALFVDCDFLYTADLRELAELIDDRYAVMCVHHDYTPKTTVKMDGVLQTSYPRKNWSSMVLYNCAHPKNKVLTPELVNSASGSFLHRFMWLEDADIGELPITWNFLVGHNELPKKGASIPKAIHFTCGGPWFEAWKDCEFADHWLKERDEYWNTQLYDIASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G575</accession>
    <name>A0A8T0G575_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G058900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G575"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022552">
        <property type="entry name" value="UPF_Ycf55"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36807">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36807:SF2">
        <property type="entry name" value="PHOSPHOGLYCOLATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12452">
        <property type="entry name" value="DUF3685"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="583" mass="64445" checksum="9C8F1BA2DAC799A3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5E9</accession>
    <name>A0A8T0G5E9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RuvB-like helicase</fullName>
            <ecNumber evidence="8">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G028600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="8"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5E9"/>
    <dbReference type="OrthoDB" id="10060499at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000010">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.360:FF:000001">
        <property type="entry name" value="RuvB-like helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.360">
        <property type="entry name" value="RuvB-like helicase, domain II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027238">
        <property type="entry name" value="RuvB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041048">
        <property type="entry name" value="RuvB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042487">
        <property type="entry name" value="RuvBL1/2_DNA/RNA_bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010339">
        <property type="entry name" value="TIP49_P-loop"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11093">
        <property type="entry name" value="RUVB-RELATED REPTIN AND PONTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06068">
        <property type="entry name" value="TIP49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17856">
        <property type="entry name" value="TIP49_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="9">
        <location>
            <begin position="62"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0553657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="49765" checksum="AF2ED3D27BDC422B" modified="2022-10-12" version="1">MKIEEVQSTTKKQRVASHTHIKGLGLKEDGTALDVGAGFVGQDQAREAAGLVVDMIRQKKMAGRALLLAGAPGTGKTALALGIAQELGSKVPFCPMVGSEVYSSEVKKTEVLMENFRRAIGLRIKENKEVYEGEVTELSPEETESTTGGYGKSISHVVIGLKTVKGTKQLKLDPTIYDALIKEKVLVGDVIYIEANSGAVKRVGRSDAFATEFDLEAEEYVPLPKGEVHKKKEIVQDVTLHDLDAANARPQGGQDILSMMGQMMKPRKTEITDKLRQEINKVVNRYIDQGVAELVPGVLFVDEVHMLDMECFTYLNRALESSLAPIVIFATNRGICSIKGTDISSPHGIPVDLLDRLVIIRTLPYTPAEMVQILAIRATVESLSLDEESLAYLGEIGERTSLRHAVQLLTPASIVAKTNGREQISKGDLEDIATLFLDAKASARLLQEQPDKYVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5J7</accession>
    <name>A0A8T0G5J7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G098800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the importin alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5J7"/>
    <dbReference type="OrthoDB" id="29145at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061608">
        <property type="term" value="F:nuclear import signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.690:FF:000002">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000040">
        <property type="entry name" value="Importin subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.690">
        <property type="entry name" value="Importin-alpha, importin-beta-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032413">
        <property type="entry name" value="Arm_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002652">
        <property type="entry name" value="Importin-a_IBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036975">
        <property type="entry name" value="Importin-a_IBB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024931">
        <property type="entry name" value="Importin_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23316">
        <property type="entry name" value="IMPORTIN ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16186">
        <property type="entry name" value="Arm_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01749">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005673">
        <property type="entry name" value="Importin_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51214">
        <property type="entry name" value="IBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="IBB" evidence="9">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="117"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="160"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="6">
        <location>
            <begin position="244"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="503"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="513"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="532" mass="58027" checksum="850463387FC102AA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6I1</accession>
    <name>A0A8T0G6I1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fibronectin type III-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G098200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6I1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000001">
        <property type="entry name" value="probable beta-D-xylosidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035791157" description="Fibronectin type III-like domain-containing protein" evidence="5">
        <location>
            <begin position="21"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="6">
        <location>
            <begin position="715"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="801" mass="88344" checksum="4D5A82B37D43C418" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7F6</accession>
    <name>A0A8T0G7F6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G089300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7F6"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF8">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="47"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="178" mass="19897" checksum="842C4CE47C279937" modified="2022-10-12" version="1">MASSSGASVLNIDITKFISPEATNRKHIAFMIRSNLTMKMLLDGLNTDITLEAKGGSRFRAHTCVLAANSPVFNAIFKTRTEERVIATVPEKLHEMTIEGLKLFVVLLYLAPVLQDNVIMNGLENAVIDHFDELVAARLKFKVPVMDPILTKALSKILTPENCGNYLYYWMIASLKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8U4</accession>
    <name>A0A8T0G8U4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G190300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8U4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="11928" checksum="984A76E4C0A56290" modified="2022-10-12" version="1">MPRAHARSSQGAHAYRGINVVNPTPPSLGTSPSTHVPEQCHGRHAAVHPTPSVPELAPPSAGPRATHHATPSDAFAVQEARSIRQEESMTRCHPSHRGPRCITSTTAPGADEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9I4</accession>
    <name>A0A8T0G9I4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Adenosine kinase</fullName>
            <shortName evidence="11">AK</shortName>
            <ecNumber evidence="4 11">2.7.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Adenosine 5'-phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G166800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine + ATP = AMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:20824"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenosine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.20" evidence="4 11"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9I4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004001">
        <property type="term" value="F:adenosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006144">
        <property type="term" value="P:purine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01168">
        <property type="entry name" value="adenosine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000006">
        <property type="entry name" value="Adenosine kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001805">
        <property type="entry name" value="Adenokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45769:SF3">
        <property type="entry name" value="ADENOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00989">
        <property type="entry name" value="ADENOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="12">
        <location>
            <begin position="5"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0555405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="298" mass="32546" checksum="A8170BCAE5A3B92D" modified="2022-10-12" version="1">MSMYKELAQRPNTTYMLGGATQNSIRIAQWLLRKPKATTFVGGIGKDEFGEKMKKLASLEGYNVAFHVDSSAATGSCAVLVVGGERSLVAYLAAAGMYKVDHLRKPENWALVEKAHYFYSAGFFLTVSPDTLMLVAKHAAATGKIFMMNLSASFICERFKDTLMAAFPYIDYIFGNENECKTFGRTQGWQTTDVGRIALKMAALPKICGTHKRIVVITQGLDPVVVADDGKICLFPVVVLPKEKLVDTNAAGDSFVGGFLAQLVFGKDMAECVRAGNYAANVVIQRPGCSFPKRPNFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC60</accession>
    <name>A0A8T0GC60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G122100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="327"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="7">
        <location>
            <begin position="66"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="347"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="41551" checksum="EC5DDF4C3B4709A2" modified="2022-10-12" version="1">MATVGVPKHRLSDGHDQLSTNFTKEDSLDDAPKTWTEGAKTWTQSVATQMGDVKVFGIAFGYCLSASLLSIINKWAIMEFPYPGSLTALQYFTAAFGVFILGKFRVLDHDPLSLTTMWKFLPAAICYYMSLFTNSELLLHANVDTFIVFRSAVPIFVAIGETIYLKQPWPSMKTWSALATILGGSVIYVLTDSQFTVNAYIWAFLYVASMSIDFVYVKHIVMTVGLNTWGLVLYNNLEALLLFPIELFVMGEGALMKTQTSDSTLDWYSLKMWLPVLLSCAFGFSISYFGMSCRRAISATGFTVLGVVNKLLTVVINLVIWTKHASAAGTLGLLICIFGGVFYQQSTTKPKPAAPEPTPAPAQADEEEGLLTSNAKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC68</accession>
    <name>A0A8T0GC68_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G123100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="12025" checksum="9948CD0A45743AE4" modified="2022-10-12" version="1">METSSICTSSIFLSQVGRSDSYKQSYQWSSSEIDWKSPKLMRFASNAISVMHYDLQLRRLEIPNLVITVFTGMKLKRPSMESDLNTSFSSSTLNFLYFVENIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCL2</accession>
    <name>A0A8T0GCL2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G076700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="16558" checksum="F611776CE40F9D8B" modified="2022-10-12" version="1">MITNCSRRITTCNHCTLHEMEAVKCMRSEAAPKLRPMISPTSQLLEIQLPISKTQTKIPNPSGNSSIADPFGARGRTETPCNGRSGIALHRKKASQEECRALQYPSKHGPFFKPGRKWTSVHTRARKASSQSCREALSRRQSRGGRGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD75</accession>
    <name>A0A8T0GD75_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G042400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ELIP/psbS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD75"/>
    <dbReference type="OrthoDB" id="48883at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000008">
        <property type="entry name" value="Photosystem II 22 kDa protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0556304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="281" mass="28852" checksum="D287CB41BD89C7A3" modified="2022-10-12" version="1">MAQAALISRVGAQAALGGSLRQVQVQGGRQLSSLFAASSSSAIPAGLGLSRNVERVASGAVKTFALFGSKKAAPAKTPAPKKAAPKVEDGIFGTSGGIGFTKANELFVGRVAMLGFAASILGEALSGKGTLAQFDIETGIPLTETEPLLIFFILFTLLGAIGALGDRGRFVDESPVAGLDSIAIKPGKGVKGAFGLNEKGPVFGFTKANELFVGRLAQLGIAFSIIGEIITGKGTLAQLNIETGVPITELEPLIIFNVIFFLFAAVNPGTGKFVNDDDIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD76</accession>
    <name>A0A8T0GD76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_11G070800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD76"/>
    <dbReference type="OrthoDB" id="2573941at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12411">
        <property type="entry name" value="RRM_ist3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051847">
        <property type="entry name" value="RNA_proc/Spliceosome_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045844">
        <property type="entry name" value="RRM_Ist3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45880:SF1">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN, X-LINKED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="36"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="9">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="158"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="229"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="163"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="293"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0556675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="50849" checksum="A241CF516F1B08F2" modified="2022-10-12" version="1">MNPLTQVKNTQKITAREHAIGITEEGSWHAKYKDSAYVYVGGLPFDLTEGDVLAVFAQYGEIVDVNLVRDKTTGKSKGFAFLAYEDQRSTVLAVDNLNGARVVGRIIKVDHVGDYKRKLEEDEEEKQRKREERGVCYAFQRGECNRGDDCKYSHDEERNANTGWGGGGAGRGDGGGSWKHDQFDGSMKEASRRMNMSSSKRNDNSIGERDDKPRGVCYAFQRGECNRGDGCKFAHDEQKNTNSGRGGGGGPGGAGWKNDQFDGSMREAGRRMNVTNTVSTKRKENDIGELDEAPQRRRDVDSGDRERGDGHRKRDDDREDRGRDDVRRRRDGDREDREREDRGRDDVQRRRDGDREDRGRDQDRKESDRRARRDDYREGSYDRKDRREDGGGRREDRRNDRRGRDDDDDVDEKDRSREVRKDRERSDRGDDSRGERSVRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDR1</accession>
    <name>A0A8T0GDR1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G037700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9170" checksum="31B9805F5BA7C931" modified="2022-10-12" version="1">MASKGAQALADHQPATTPRLLKPAEKCKLIRKRKRDAPNKLPCSKRQEKSEVDSISLEDQLRALQLHDSAAGGNKVSCCKAFGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEH2</accession>
    <name>A0A8T0GEH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_11G036600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF47">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0556228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="281" mass="30441" checksum="C9C39CA8C02C1F6D" modified="2022-10-12" version="1">MGGWGGVGWGREAIGWTPQMPTAVTAGSIWRPAGTVGASRFDAVINFAGLKAVGESCAKPLPYYINNILGTLNLLDVMSTRNCKKFVFSSSATVYGQPESVPVTEESRLYVLNPYGRTKLQVEEMMRDITAADSDWRTIVLRYFNPVGAHPRGRLGEDPQGIPNNLMPFVQQVAVGRRKELTVFGNDYDTKDGTGVRDYIHVQDLATGHSAALHKLFTTPDIGCTAYNLGTGKGTSVLEIVAAFEKAAGLKIPLRIADRRPGDCSVVFTATDKAGKELGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHS3</accession>
    <name>A0A8T0GHS3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G160600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8837" checksum="C9FA0BA49CD29575" modified="2022-10-12" version="1">MHRGMGQEERGLQFTDIKASNDDVLEAADMYFRSNICLFISIMISTYLQNQHYDIDYDIPAEIDICVHKIRHTER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJT9</accession>
    <name>A0A8T0GJT9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RWD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G092500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJT9"/>
    <dbReference type="OrthoDB" id="2019251at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140469">
        <property type="term" value="P:GCN2-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006446">
        <property type="term" value="P:regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23821">
        <property type="entry name" value="RWD_IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="entry name" value="Impact, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006575">
        <property type="entry name" value="RWD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="IMPACT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301:SF25">
        <property type="entry name" value="PROTEIN IMPACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="Impact_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05773">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00591">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50908">
        <property type="entry name" value="RWD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="RWD" evidence="7">
        <location>
            <begin position="12"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="325" mass="36277" checksum="022C25132BB19272" modified="2022-10-12" version="1">MEVEENRIAQAEELEVLRSIYGEEDCQISSTNQFCEVKVYPADGSSNGELSLRLGVHLPESYPSASCPVAELHASWLSENSRRQVVEMLTSLYEEAVGEVVVFRWVEWLKEQDWLWEEARRWILERAPPVQIIDEKVATTASLDSHLPEEVVLHTSLQSSERILDEKGLEELDRILGIVHGEPFTEKRSTFQAHLAPAKSADDVEAVMDALLRNRKIAAATHNIMAYRISMPIKNTVLQDNDDDGETAAGGRLLHLLQIVNALNVIVVVSRWYGGIQLGPDRFKHINNAARSLLGSCGYIAGVNSSATANQKTLPKSNLQKGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GML0</accession>
    <name>A0A8T0GML0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxidase</fullName>
            <ecNumber evidence="13">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G015100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="10 13">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="10 13">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="13"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GML0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 13" id="KW-0349">Heme</keyword>
    <keyword evidence="13" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 10 13" id="KW-0408">Iron</keyword>
    <keyword evidence="4 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 13" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0964">Secreted</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035966655" description="Peroxidase" evidence="13">
        <location>
            <begin position="32"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="14">
        <location>
            <begin position="32"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="11">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="75"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="124"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0558272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="322" mass="34291" checksum="EED0F042F5B7B88E" modified="2022-10-12" version="1">MAVRSAARGTMLAFAAVLAALLMCLSAGVEATLTYDFYSSSCPHVEYLVYQEISKAYWNDSTVAPGILRLSFHDCFVNGCDASVLVAGNTTERAAIQNAGIHGFEAINAAKWAVEQMCPGVVSCADILQYAARDTVKLTKGLGWGVPAGRRDGTVSLATDPPLNLPPATFTSSELVANFAAKGLSAEQMVILSGSHTIGVTHCLQLRDRIFDVIDPTMPKDLLATLQAACPTNTTPTALTIDRSTVDTFDTNYFSNIASGYGLMTSDQTLFADSATRPYVEANLLQGVFDSNFAAAMVAMSSISPKVGTEGEIRHHCEYFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNU2</accession>
    <name>A0A8T0GNU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G005400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035896293" description="Secreted protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="8199" checksum="BBBE9550641EB982" modified="2022-10-12" version="1">MRSAIYSSLLVPLLLTNLLTKLVFCVPWLRSCPRTPPRIYSLALLRLRLPLWAPPYPGWALQPSVRLGWQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQC0</accession>
    <name>A0A8T0GQC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G045600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="229" mass="25552" checksum="4B81AF819D897898" modified="2022-10-12" version="1">MSIPRQRFVGNLHSLVSNELTVLQALLLVLWLICVSVHKLSGAAAELLERWFLSSFEGETSSQGEPADLVTRAEPSSLLSAEVRDGSPQGVAEPIGSLIPSLPDTIVREQVWPKLVSNPSVTQLLQFRHINSSWSQFVGATLEWRALIFVMLDFPGYLQQVRQHGLIFLSATQRLGLEIAHYKLLVSESMEEIESRIEFAGFQTRRLPSYVSLEGCPPCVDEDPGYYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSK0</accession>
    <name>A0A8T0GSK0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G001800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13857" checksum="422945FBF3D719A6" modified="2022-10-12" version="1">MRTLPHRVQRCSPRSENHKRYACPDTNAASAQNITLMATEFMERALSLLQPPAASTLQHGPVNWPQINIHPDIYISRQIYRSFSYLPEANSTKMLPLAAIKRNRKEIVDHRTKHIQRQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUE1</accession>
    <name>A0A8T0GUE1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">mannan endo-1,4-beta-mannosidase</fullName>
            <ecNumber evidence="4">3.2.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G090000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Random hydrolysis of (1-&gt;4)-beta-D-mannosidic linkages in mannans, galactomannans and glucomannans.</text>
            <dbReference type="EC" id="3.2.1.78"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.78" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016985">
        <property type="term" value="F:mannan endo-1,4-beta-mannosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000012">
        <property type="entry name" value="Mannan endo-1,4-beta-mannosidase 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045053">
        <property type="entry name" value="MAN-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31451:SF39">
        <property type="entry name" value="MANNAN ENDO-1,4-BETA-MANNOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26410">
        <property type="entry name" value="GH5_mannosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glycoside hydrolase family 5" evidence="9">
        <location>
            <begin position="76"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF26410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="455" mass="50077" checksum="DBE8E4D9FA5E80EA" modified="2022-10-12" version="1">MEIDLPGRGRRSRCFSLSVMNTLHLVMSALFLLAMRNATDALRPKYESAIPRLPHHRLQARVVHRRGLKATSGNGEFVKASGHQFTFGGKALYVNGANIYWLMNRATDESSRSAVREVLQEAAGVGVTVVRTWAFADGNDYHPLQLTPGVFDESVFQGLDYVVSEAKNNGIRMILSLVNNYGDYGGKPQYVAWANEKGGNLNSEDDFFSDATTRGWFKDYIKTVATRVNTITGVAYREEPAIFAWELMNEPRCSSDTTGNTVQAWLEEMAAYVKSVDENHMLTTGLEGFYSSTVSSDSVVQESSNPGSYATQYGVDFIRNHQVSGIDFASVHLYPDNWMPTSAESEKQEFVSKWIQTHVNDGAVTLKKPVLFGEFGKSRDVAGYTESVRVSTMTAMYDAIYNSGAEGGAGTGALVWHLITNTTTALADGFEIILSSDTNIASLMQKQSSRLSSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUJ6</accession>
    <name>A0A8T0GUJ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G157500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="293"/>
            <end position="558"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="598" mass="67858" checksum="3F93E99D99DF090F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVK9</accession>
    <name>A0A8T0GVK9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G140700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVK9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035820618" evidence="1">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6242" checksum="5A54976226A4C63F" modified="2022-10-12" version="1">MRSMAASLMVFSVFWSIPCFDCAAISATKNNNFGNSACAGAFKVLPTHSIFAETNCEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVM5</accession>
    <name>A0A8T0GVM5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G087400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035725943" evidence="1">
        <location>
            <begin position="25"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6730" checksum="B23F68FF58718C2A" modified="2022-10-12" version="1">MLRLIVCNEVILVLWHLLLKGCKQITTIRCTVRELLIKLLSRDNIRHYFQTYFKAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW96</accession>
    <name>A0A8T0GW96_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G077400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="16577" checksum="2E032143AE63F3B0" modified="2022-10-12" version="1">MNPNCGINAATRSIQIYTILGAKLAFSVNLATWFKVDHHDISRAPTLPGSLYDMSGVPAPAHAAQIVPNAAKVEEGVDVVHPGPGSGLLVSHRVSNLVLLPPQSRQRIISLHTPPHVPPRVCGSRHLSISMSQGVHDFSQKLAMNYNNASLRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWR4</accession>
    <name>A0A8T0GWR4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G187500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045166">
        <property type="entry name" value="Spp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026822">
        <property type="entry name" value="Spp2/MOS2_G-patch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818">
        <property type="entry name" value="G PATCH AND KOW-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15818:SF2">
        <property type="entry name" value="G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12656">
        <property type="entry name" value="G-patch_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="4">
        <location>
            <begin position="172"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="186"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="222"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="45030" checksum="DE477E66ACBC868E" modified="2022-10-12" version="1">MAEGEGNGVEGGGGGAGEKKVMKFSFSKTKPSNRRPPLPPKGKEKEDVVVEYVTSVDAEAGIVVVNPRAGSGVKVVPKLENSWRPEKRMKNIMMESDSTKSTDETFEMETIDAGPKANVQYGLTLMERVESEGVAEAPRRMSLKELEDQKLREDLTNLPEEATLDQYEELPVEAFGEALLRGMGWEKGKPIGRNSKTIVEPVEYTRRQGTLGLGATPPPPKETNKKYIKPGETRDRRRVDYDKPRDSREKRRDEESRENGRDEYIKPEKSRDSRREEYINPRDSREHRREVDLRESRRDDYIEPRDSRESRREDESRRSRRDDDTESRDSREKKREEHRKPKDSRESRREEFSETRDSREKRRDDYSRSDEHRESRREQKRSNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYP3</accession>
    <name>A0A8T0GYP3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G051400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="61"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="13903" checksum="5CE0B4DD307E398A" modified="2022-10-12" version="1">MFFVSTDSELAQKLKQVLQFKQNETSFSHITSTHGITPQHQPKAEPPFKTSSNTNISKICSLSTNNSNHTNRTSAQRPQSSTTSRTEQFNPQKTLTLLELQSVSRNNIKTQSPTKPSETLILKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZC8</accession>
    <name>A0A8T0GZC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G034200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="316" mass="34774" checksum="43DD712FF33A31BB" modified="2022-10-12" version="1">MPRGRPAKGNAKNGQPAKATEEADATPVKEPLVEEQGTRYSMRTRGQSKGGETKENGQDAKTAEQKKKPGRKRKAGPADEEKSQESTVVPDVKKDEAEEPAKKEEEPKDDAKEDVKEEEEEEEEEPKAEAKDEGTDTPRSSKEGEIKVNRAPVLTMWVAAVAERQGFTFDEAVTFGKAISGLFAHSKGKKIGVIEDGPKDPEAESDKKKAKKEKFDVFGNSVYGKTTDKGRFALESGKAIAPNSVKAYLHRAFKDDYDRVREAFEALANSLEPEEIGSRAYHLYEKFRPEVPDGARGWGARGLLDLKHVQELAASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZY4</accession>
    <name>A0A8T0GZY4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TPX2 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G023400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TPX2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZY4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027329">
        <property type="entry name" value="TPX2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044806">
        <property type="entry name" value="WVD2/WDL1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46372">
        <property type="entry name" value="PROTEIN WVD2-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46372:SF2">
        <property type="entry name" value="PROTEIN WVD2-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06886">
        <property type="entry name" value="TPX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0493">Microtubule</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPX2 C-terminal" evidence="7">
        <location>
            <begin position="425"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="167"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="311"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="428"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="519"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="580" mass="62709" checksum="482A1FD68F628239" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H023</accession>
    <name>A0A8T0H023_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G027100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H023"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000:SF642">
        <property type="entry name" value="INACTIVE LEUCINE-RICH REPEAT RECEPTOR KINASE XIAO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0563388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="7891" checksum="E30DDA5E6B2539F3" modified="2022-10-12" version="1">MTKLKWLFMSNNNLSGSIPAELGNLGSLEVLDLASNALSGTLPDSLCQRSTLSIYLDHQGDVPPVKFNRSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H345</accession>
    <name>A0A8T0H345_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G137500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H345"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035888419" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5731" checksum="06384CA67B0B6796" modified="2022-10-12" version="1">MGCLCSLLLQILRIGILLNLFFNEAHVSSGTRNYGYLRIHVTLAFCRILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H353</accession>
    <name>A0A8T0H353_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Mitochondrial carnitine/acylcarnitine carrier-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G139000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H353"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000064">
        <property type="term" value="F:L-ornithine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990575">
        <property type="term" value="P:mitochondrial L-ornithine transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000050">
        <property type="entry name" value="mitochondrial carnitine/acylcarnitine carrier-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050567">
        <property type="entry name" value="Mitochondrial_Carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624">
        <property type="entry name" value="MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45624:SF12">
        <property type="entry name" value="MITOCHONDRIAL ORNITHINE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="103"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="223"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0564774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="312" mass="32040" checksum="B1E30BABAEDEA959" modified="2022-10-12" version="1">MSDAVAKDLTAGTFAGVAQLLVGHPFDTIKVKLQSQPVPLPGQPPKYAGAMDAVKQTLAGEGTKGLYKGMGAPLATVAVFNAVLFTARGQMEALLRDAPGAHLTVGQQMIAGGGAGVACSMVACPTELVKCRLQAQSALATAVEPALAGVGAAGGTAAVKGAVQYSGPLDVARHVLRSEGGMLGLYKGLTPTLMREVPGNAAMFGAYEATKQYLAGGQDTSSLGRGSQLFAGGVAGAMFWVSVYPTDVIKSVIQIDDHRNPKYKGTMDAFKKVFANEGVKGLYRGFGPAMARSVPANAACFLAYELVRESLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H606</accession>
    <name>A0A8T0H606_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G045800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H606"/>
    <dbReference type="OrthoDB" id="27435at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034098">
        <property type="term" value="C:VCP-NPL4-UFD1 AAA ATPase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097352">
        <property type="term" value="P:autophagosome maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051228">
        <property type="term" value="P:mitotic spindle disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030970">
        <property type="term" value="P:retrograde protein transport, ER to cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19519">
        <property type="entry name" value="RecA-like_CDC48_r1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19528">
        <property type="entry name" value="RecA-like_CDC48_r2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000004">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.330.10:FF:000001">
        <property type="entry name" value="Cell division control 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.40.20:FF:000003">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000012">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000048">
        <property type="entry name" value="Transitional endoplasmic reticulum ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF171">
        <property type="entry name" value="NUCLEAR VALOSIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="ADC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="Cdc48 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48 N-terminal subdomain" evidence="6">
        <location>
            <begin position="40"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48" evidence="5">
        <location>
            <begin position="140"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="251"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="524"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="722"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="783"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="732"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="793"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0566205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="822" mass="90663" checksum="680A82A0A59E329F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H750</accession>
    <name>A0A8T0H750_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G077800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H750"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048250">
        <property type="term" value="P:iron import into the mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF4">
        <property type="entry name" value="MITOFERRIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="51"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="147"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="243"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0566615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="343" mass="36888" checksum="7E556EE0308D7848" modified="2022-10-12" version="1">MAEGVADVLRERHFLAKRENVKSYGGAGEAPGAPPLLQQQQREEHELHDGLGFGQYMLAGSIAGMVEHMAMFPVDLVKTRMQMLQSAGGSAHSTVYKAFFAIMQKEGPLGLYRGIGAMGLGAGPAHAVYFAAYETLKEKFGGNASGHHPFAHGLAGAGATIASDAVFTPMDVVKQRLQLRHSPYSSVLDCIKKTMKEEGFSAFYKSYRTTVVMNVPFTAVHFAAYEAGKKVLAGLYPEYADEEHLLMHITAGGAAGALASAVTTPLDVIKTRLQCQGVCGADRYASGSVLAAARSIVKREGPGSLWRGMRPRVMFHTPAAAICWSTYEAGKSFLQGWNDDQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7Y5</accession>
    <name>A0A8T0H7Y5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G129300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041070">
        <property type="entry name" value="JHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050690">
        <property type="entry name" value="JHDM1_Histone_Demethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23123">
        <property type="entry name" value="PHD/F-BOX CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17811">
        <property type="entry name" value="JHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="JmjC" evidence="11">
        <location>
            <begin position="155"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="430"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="437"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="529"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0567360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="556" mass="61788" checksum="CA99AEC45D1F07FF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7Z4</accession>
    <name>A0A8T0H7Z4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G182700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009734">
        <property type="term" value="P:auxin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010928">
        <property type="term" value="P:regulation of auxin mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06410">
        <property type="entry name" value="PB1_UP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000142">
        <property type="entry name" value="Octicosapeptide/phox/Bem1p domain kinase superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000058">
        <property type="entry name" value="Octicosapeptide/phox/Bem1p domain kinase superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000081">
        <property type="entry name" value="Octicosapeptide/phox/Bem1p domain kinase superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000270">
        <property type="entry name" value="PB1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF963">
        <property type="entry name" value="AT08303P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00564">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00666">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0927">Auxin signaling pathway</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="1367"/>
            <end position="1632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="436"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="653"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="738"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1019"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1286"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="445"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="748"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="803"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1026"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1286"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1336"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="1394"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0568051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1645" mass="180012" checksum="5174F00B6FC47009" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H824</accession>
    <name>A0A8T0H824_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G132400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H824"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="11127" checksum="04663D20FF98ED06" modified="2022-10-12" version="1">MMESVRQLPNVVTSHIPDKTTQKPETLTHQPFLIRKCKDLSNTLELKPGDLAYEFGGTRSEGWNCLFLLLGSDGSCSTNEPPHHELVMMRFTTMQILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAF5</accession>
    <name>A0A8T0HAF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA replication licensing factor MCM2</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">DNA replication licensing factor mcm2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_6G007000</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042555">
        <property type="term" value="C:MCM complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000727">
        <property type="term" value="P:double-strand break repair via break-induced replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902975">
        <property type="term" value="P:mitotic DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17753">
        <property type="entry name" value="MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.10:FF:000002">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000138">
        <property type="entry name" value="DNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1640.10">
        <property type="entry name" value="mini-chromosome maintenance (MCM) complex, chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008045">
        <property type="entry name" value="MCM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018525">
        <property type="entry name" value="MCM_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027925">
        <property type="entry name" value="MCM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059098">
        <property type="entry name" value="WHD_MCM2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630:SF44">
        <property type="entry name" value="DNA REPLICATION LICENSING FACTOR MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12619">
        <property type="entry name" value="MCM2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14551">
        <property type="entry name" value="MCM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23669">
        <property type="entry name" value="WHD_MCM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01658">
        <property type="entry name" value="MCMPROTEIN2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00847">
        <property type="entry name" value="MCM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0347">Helicase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MCM C-terminal AAA(+) ATPase" evidence="19">
        <location>
            <begin position="490"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="37"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="18">
        <location>
            <begin position="172"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00074927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0568260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="916" mass="103756" checksum="48B747FC2314D41C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAW0</accession>
    <name>A0A8T0HAW0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G140700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046510">
        <property type="term" value="F:UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046506">
        <property type="term" value="P:sulfolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03814">
        <property type="entry name" value="GT4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000044">
        <property type="entry name" value="Sulfoquinovosyl transferase SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000062">
        <property type="entry name" value="sulfoquinovosyl transferase SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050194">
        <property type="entry name" value="Glycosyltransferase_grp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45947:SF3">
        <property type="entry name" value="SULFOQUINOVOSYL TRANSFERASE SQD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase subfamily 4-like N-terminal" evidence="3">
        <location>
            <begin position="143"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="2">
        <location>
            <begin position="325"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0567518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="525" mass="57467" checksum="C7F3AD846C781FA1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBH9</accession>
    <name>A0A8T0HBH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G073200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035834202" evidence="1">
        <location>
            <begin position="25"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9527" checksum="44E37A5C4728D179" modified="2022-10-12" version="1">MSRIRLIAELLALISLQYYSWSTARTSVEDTISERNSVQQFHKYLIAMIKLRNELKYDGSDGSDGNQDLVCKFLSTFTVFGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCP0</accession>
    <name>A0A8T0HCP0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G001900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCP0"/>
    <dbReference type="OrthoDB" id="1957471at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035794711" evidence="1">
        <location>
            <begin position="19"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15891" checksum="BBCC88F0B70F2062" modified="2022-10-12" version="1">MARVAFFLSMFMMMAVSAQQSGPRLGFFNYSGMHATIRCVDHPSGILEAGGTFFIPLTRSDQACVVTLKDGEHASAVIDKVLPISSNSGLSVSVDINDTFLFFSLDETHHHQYVSFLNTQEKHIPVQRSSDLQLWSMEESTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFD3</accession>
    <name>A0A8T0HFD3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.258</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G155100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl beta-D-mannosyl phosphate = an alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;3)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-alpha-D-GlcNAc-diphospho-di-trans,poly-cis-dolichol + a di-trans,poly-cis-dolichyl phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:29527"/>
            <dbReference type="Rhea" id="RHEA-COMP:19498"/>
            <dbReference type="Rhea" id="RHEA-COMP:19501"/>
            <dbReference type="Rhea" id="RHEA-COMP:19516"/>
            <dbReference type="Rhea" id="RHEA-COMP:19517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57683"/>
            <dbReference type="ChEBI" id="CHEBI:58211"/>
            <dbReference type="ChEBI" id="CHEBI:132515"/>
            <dbReference type="ChEBI" id="CHEBI:132516"/>
            <dbReference type="EC" id="2.4.1.258"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:29528"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.258" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052925">
        <property type="term" value="F:dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007873">
        <property type="entry name" value="Glycosyltransferase_ALG3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646:SF0">
        <property type="entry name" value="DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12646">
        <property type="entry name" value="NOT56 - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05208">
        <property type="entry name" value="ALG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="183"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="405"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0570343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="440" mass="49401" checksum="D2D675DF51AD568F" modified="2022-10-12" version="1">MAMADSKSREAVTKAMAKAKAPSPMVSPRDGRSRLISSACGLLLFDAVLTAIIIARVPYTKIDWDAYMSQVTGFLAGERNYAEIHGDTGPLVYPAGFLYIYSGIQYITGGAVFPAQILFGVLYVINLGLVLLIYIRAQAVPWWALSLLCLSKRIHSIFVLRLFNDCVATTLMHASVALMQQQHWHLALTVFSAAVSVKMNVLLLAPPVLLLLLKSLTVWGVLTSLGCAAILQVLVGMPFLLTYPMEYFSRAFNLGRVFIHFWSVNFKFVPEDFFISKPFALSLLILHLGFLFVFAQYKWCRHEGGILRACGPQNVREEPKKSDLNVVDKFLRSVQSLSANHILTVVFTGNFIGIVFARSLHYQFYSWYFYSLPFLLWKTTFPTPVRLAIFFGTELCWNVYPSTPVSSVALLLCHVSLLAGLWFAPSEYPYVDRTKEIKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGL8</accession>
    <name>A0A8T0HGL8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G092200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGL8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="15087" checksum="B169D5E680C1350E" modified="2022-10-12" version="1">MSNIGLRQQLRLEETQLATVPEECEKSPKKNKKVSMGLARLKRSPYLVKQQSPQRERLITYKKEVISNRLPSAYRYFKTVEFRKPSKYDIGSTEDCCFVDNQDDDKSKEPGIDEVQYVMTKYAKNMPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGU0</accession>
    <name>A0A8T0HGU0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribulose bisphosphate carboxylase small subunit, chloroplastic</fullName>
            <shortName evidence="7">RuBisCO small subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RBCS</name>
        <name evidence="11" type="ORF">KC19_6G173200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">Heterohexadecamer of 8 large and 8 small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RuBisCO small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03527">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.10:FF:000001">
        <property type="entry name" value="Ribulose bisphosphate carboxylase small chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.10">
        <property type="entry name" value="Ribulose bisphosphate carboxylase, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00859">
        <property type="entry name" value="RuBisCO_S_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024681">
        <property type="entry name" value="RuBisCO_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000894">
        <property type="entry name" value="RuBisCO_ssu_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036385">
        <property type="entry name" value="RuBisCO_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL CHAIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262:SF0">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL SUBUNIT, CHLOROPLASTIC 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00101">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00152">
        <property type="entry name" value="RUBISCOSMALL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00961">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55239">
        <property type="entry name" value="RuBisCO, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="6 7 8" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="1 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7 8" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="2 7 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035868172" description="Ribulose bisphosphate carboxylase small subunit, chloroplastic" evidence="9">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Ribulose bisphosphate carboxylase small subunit" evidence="10">
        <location>
            <begin position="72"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0570590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="19818" checksum="2303D328DEC5CFA6" modified="2022-10-12" version="1">MASVVAASTVVAPAAFAAASSCVGSSESTSVKAFSGLKSATLVSAKSQTLSSVQNGSRVQCMQVWNPTGNLKFETFSYLPALSEQDISKQVDFMIRQKLIPCLEFDPVGVISRTNNRSPGYYDGRYWTMWKLPMFGCNDSSQVLREIQECKKAFPQCYIRVLGFDNIKQVQIAGFMVAAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIW6</accession>
    <name>A0A8T0HIW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">L domain-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G142300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIW6"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053038">
        <property type="entry name" value="RLP_Defense"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064">
        <property type="entry name" value="OS01G0750400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48064:SF1">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN 51-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="536"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0570152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="567" mass="57856" checksum="F0FF2912C2CB1678" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ13</accession>
    <name>A0A8T0HJ13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G175800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="39"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1155" mass="132553" checksum="4271D7A02409C4EB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMM0</accession>
    <name>A0A8T0HMM0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG071000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMM0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15365" checksum="826D9B2326E1A295" modified="2022-10-12" version="1">MTYISSGNSKSSHQKQRNAPQEKLDEDASRSKHTHHKQPLHVYLCSEMLLKRRGGCTVPRGEPRCCSRDNRCCYAEVQSMSEGVYVVRAGRVYSTLCTVKAVSGGRTPPPTPLSAPTADVGEGAEVGEVRRRRGGAPRRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNV5</accession>
    <name>A0A8T0HNV5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG104900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035918760" evidence="1">
        <location>
            <begin position="16"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="30" mass="3541" checksum="A53C7F288175179A" modified="2022-10-12" version="1">MIAVLLLLCECYSFGFNIVYSRERQERLCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPG1</accession>
    <name>A0A8T0HPG1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG099400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="16935" checksum="1CDCADB7F10879BD" modified="2022-10-12" version="1">MADVSDTFLYAVAIDSDDGDKVHSSQDRGCKPRSVDRTDRADEALLVRTPVLSEMPKLKPNVQPLSRPPSPGSPPNYSRWAPCPVCTYKQRKVAPVEMASEHELPRASPISLAPVRRLEVLSHNLRQKQKYQDHLKFVRADPELTYLEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSB6</accession>
    <name>A0A8T0HSB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG220700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035746285" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="61" mass="7291" checksum="3B771E3972CE8254" modified="2022-10-12" version="1">MFIVYRRLLRSWFQLAVVGVFGFLEQHQRRCDYSFDSQRCSNARSILLPHYDCKFDAPCSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSJ8</accession>
    <name>A0A8T0HSJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein DGCR14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG210700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ESS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019148">
        <property type="entry name" value="Nuclear_protein_DGCR14_ESS-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940">
        <property type="entry name" value="ES-2 PROTEIN - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12940:SF0">
        <property type="entry name" value="SPLICING FACTOR ESS-2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09751">
        <property type="entry name" value="Es2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="429"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="482"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="512"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0573806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="525" mass="57041" checksum="AB04CB296A2608EE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSQ1</accession>
    <name>A0A8T0HSQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ENT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG230700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050832">
        <property type="term" value="P:defense response to fungus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20404">
        <property type="entry name" value="Tudor_Agenet_AtEML-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.40">
        <property type="entry name" value="ENT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033485">
        <property type="entry name" value="EMSY-LIKE_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005491">
        <property type="entry name" value="ENT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036142">
        <property type="entry name" value="ENT_dom-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432:SF22">
        <property type="entry name" value="OS10G0436850 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33432">
        <property type="entry name" value="PROTEIN EMSY-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03735">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01191">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158639">
        <property type="entry name" value="ENT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51138">
        <property type="entry name" value="ENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENT" evidence="4">
        <location>
            <begin position="68"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="138"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="328"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="462"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="172"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="480"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="504"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0574050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="541" mass="58204" checksum="8C1EA8DFDCC2AF0B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUP3</accession>
    <name>A0A8T0HUP3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PUM-HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG262600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012959">
        <property type="entry name" value="CPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033133">
        <property type="entry name" value="PUM-HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040059">
        <property type="entry name" value="PUM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13389:SF0">
        <property type="entry name" value="PUMILIO HOMOLOG 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08144">
        <property type="entry name" value="CPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00025">
        <property type="entry name" value="Pumilio"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50302">
        <property type="entry name" value="PUM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50303">
        <property type="entry name" value="PUM_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="PUM-HD" evidence="6">
        <location>
            <begin position="104"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="Pumilio" evidence="4">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="443"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="460"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="497"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0574445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="691" mass="77504" checksum="F869E04BF5BE1CEF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVN9</accession>
    <name>A0A8T0HVN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG324100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009927">
        <property type="term" value="F:histidine phosphotransfer kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF72">
        <property type="entry name" value="OSMOSENSING HISTIDINE PROTEIN KINASE SLN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0575172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="10686" checksum="886EEC12DBD909F7" modified="2022-10-12" version="1">MIATLFCSIAASKLDLLFEKFTQCSSSTTSTYGGTGLGLAVSKRLVELMGGTIGVVSEEGKGSKFTFTIPPELRSRVLPVEFEVYYDNFDVLRKFSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW69</accession>
    <name>A0A8T0HW69_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG304200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34211">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34211:SF3">
        <property type="entry name" value="CALCINEURIN-LIKE METALLO-PHOSPHOESTERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="681"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="767"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="881"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="3">
        <location>
            <begin position="386"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1081"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0574941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1106" mass="125783" checksum="09A1D43B66E898A9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWC5</accession>
    <name>A0A8T0HWC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dynein heavy chain AAA lid domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG322600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.720">
        <property type="entry name" value="Region D6 of dynein motor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041658">
        <property type="entry name" value="AAA_lid_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042219">
        <property type="entry name" value="AAA_lid_11_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026983">
        <property type="entry name" value="DHC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878:SF68">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22878">
        <property type="entry name" value="DYNEIN HEAVY CHAIN 6, AXONEMAL-LIKE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18198">
        <property type="entry name" value="AAA_lid_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynein heavy chain AAA lid" evidence="1">
        <location>
            <begin position="23"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="23955" checksum="8DC057B3F6BCA531" modified="2022-10-12" version="1">MMRLYAATTEESFYLCKSQEKYQKLHFALAYFHSVLLERRKFGTLGLNIPYDFNDTDFEVSNDLLTTYLDEYEETPFDALKFLISEANYGGRVTDEIDRRVLAAYLNQFYCPPILSVPNYELSTLTAYHVPDDGTLQTHREFIKTLPTTDRPEAFGQHANADIAFQLSDSRLLLQTIAGLQGGGGGGGSGAGAEELVLNICQDLLLQMLLWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWW0</accession>
    <name>A0A8T0HWW0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG323500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="entry name" value="Palm domain of DNA polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8518" checksum="B35F9688926295B7" modified="2022-10-12" version="1">MFCMQDSIVVLDFAFLYPSLFMDYNLKGCKMEVMLCKTKAEVPWKFVELLVPLIWPHTILRLFTVMCAFETM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXG4</accession>
    <name>A0A8T0HXG4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG339200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXG4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12147" checksum="CFC6D9E8951C74C8" modified="2022-10-12" version="1">MRPLSQTIHNHHDLGAAKSNDLSSTRRTTRAPKGLLKQMKRRSESNITMKELAELIHIYSMQRHGVGQRDRCCKDSEGEPVDVRWLTIRNYDNLQPPKTMGSTAFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I248</accession>
    <name>A0A8T0I248_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G138100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I248"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12248" checksum="02D0568CFF94B289" modified="2022-10-12" version="1">MSQFRYAAINILRSSTPHLVLIYKSQSCRPMPSSFLYLFPYANKKTIPHSNLPNSKLRYRSNCHRSSFLSNSVNDVQSICFHQVLQAALSFVDVCQFNCFQNANHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2F1</accession>
    <name>A0A8T0I2F1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G146200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2F1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000117">
        <property type="entry name" value="Monoglyceride lipase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="154"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="421" mass="46158" checksum="1672B848025528D8" modified="2022-10-12" version="1">MSLMAAPRSLYVGSTAGESGMEKHAQAGGAPVGYYFSPFTLGSFPLRALRRLAMAFNSLSAMAPASFRFSASRMAKQKKGEAGEGKSGSSQPRLPLLWFPRFGRSVKEINEVQKRRKLATERFSDDGETGRKVVSFVNSRGQTLFSQSWTRVQELRALVIVLHGLNEHSGRYAEFAMHLNDQGYGVFGMDWIGHGGSDGLHGYVESLDHVVSDTIEFLQRVRAEHPGLPCFIYGHSTGGAIAVKAASQPEVLELLEGGIILTSPAVKVKAAHPVIGAVAPLFSVLLPRYQFQGVNRKLAVCRDPAALVTKYTDPLVYTGNIRVRTGTEILRLSSYLLKNLKSVKIPFLVLHGSDDQVTDPTGSQDLYDQASSSHKDIKLYQGLLHDILFEPERIEIIGDILEWMDNRLARINAGEKATADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2T6</accession>
    <name>A0A8T0I2T6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G179800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2T6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="199" mass="22372" checksum="27E919FCF5F04EBD" modified="2022-10-12" version="1">MSWRIDNPQNVRFEEETSDTHSHDRPHTEESIIQPGAQPEAQAQAQAQAGALKVRDPEEVRRSVDLLNNAAISRANSVRFAMDEEHPLFGDAVGKADLEDLEELEERSLTLIEGRRMSVANASVSYQDDQAGRASRRSLAGIVIDADAPAERSMRDYSIERRSIVEPGNPVPECLGRRGCRSTQRESLVMARYWRMRPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2U5</accession>
    <name>A0A8T0I2U5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G148700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PER33/POM33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2U5"/>
    <dbReference type="OrthoDB" id="2017147at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071786">
        <property type="term" value="P:endoplasmic reticulum tubular network organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061024">
        <property type="term" value="P:membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051645">
        <property type="entry name" value="PER33/POM33_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005344">
        <property type="entry name" value="TMEM33/Pom33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12703:SF4">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03661">
        <property type="entry name" value="TMEM33_Pom33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="75"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="39867" checksum="230A52A79DF70715" modified="2022-10-12" version="1">MAGEAQGGRRAAAEAYAYDDDSRWSDYWNNVLIPPHLSAKPEVRRHFQLKFYQRFVDPEFVVEPLSSMKDGTKDSAASSSVPRGPNVTVNQRPATTGTNTARSTAGSAPPRPPRAAPPADGTLQLDQKSFQFLNNAWVVVMAIFAIFPFLPRGISDRGYRFSLAGNAIACAHCLYLNNQRPRSWNLRGLQQWLQSVVPSKDFLSFMYSLIFFSSIHPIKFAVIPVFCRSLEESATFLRRNFSNTQLYKRFLQRPCELLASNRTMLQMTSANSEIGIGFQLIFMIITPQRNLVQALIYWQLLKLFYRAPYTSQYHQQVWSRIGAKADPLIHRFAPVLERPLDYVRNWFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I323</accession>
    <name>A0A8T0I323_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Brix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G162400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BRX1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I323"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10480:FF:000009">
        <property type="entry name" value="Ribosome biogenesis protein, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007109">
        <property type="entry name" value="Brix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026532">
        <property type="entry name" value="BRX1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13634:SF0">
        <property type="entry name" value="RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04427">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00879">
        <property type="entry name" value="Brix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52954">
        <property type="entry name" value="Class II aaRS ABD-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50833">
        <property type="entry name" value="BRIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="Brix" evidence="6">
        <location>
            <begin position="64"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="42544" checksum="9F0176596716AD74" modified="2022-10-12" version="1">MGKKRKSQQVVAPPATPVVEAEPPRKRTLLGLKPQPEPEVVETKAENGSNGAAAAAVVPFRNKEKTLVLCSRRITFRYRHLMMDIMALLPHSKKDVKVQAKDNKADTLNELADLKGCSSCLLFECRKKKDLYMWLSKSPSGPSAKFLLKAVHTTEELKLTGNHLKGSRPLLSFSSEFEMHPHLQLLKELLLQVFCTPKDHRKSKPFFDHVFTFSFLDNHIWFRNYQISVPHQSATNKIDRAALEKMTLVEAGPRFAMNPIKIFSGSFGGQTLFENPFYISPNAVSLIFQFVYTSSVMSSFSLMEEKLFRQLHMRRYISLIVDIYFVQERSLDKKKKAGKYQKKVKAKQRRKTYESVNQLEPSELADVWDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I395</accession>
    <name>A0A8T0I395_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G126000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I395"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="15698" checksum="712CC216BBFAA25B" modified="2022-10-12" version="1">MSIASRRATLSSPSPDALRLPGCVADRSSSLRTSPRSPVVWKVGFYGFARGHVVRFLGFGRQRPRDSSLGSDLGVEETTGVSSGRCGSARRWREEVVGEALRIWGVWGVSCARGGRAGSRGVDNGVALQGWISFDRYRGSDMGHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3J2</accession>
    <name>A0A8T0I3J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G151000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3J2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000024">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47988">
        <property type="entry name" value="SOMATIC EMBRYOGENESIS RECEPTOR KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035732337" description="Leucine-rich repeat-containing N-terminal plant-type domain-containing protein" evidence="4">
        <location>
            <begin position="25"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="5">
        <location>
            <begin position="26"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="80"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="21038" checksum="D9734304D587AD2B" modified="2022-10-12" version="1">MPPHHVAWWRPLFLIALMPIGVLGNLEGDALNAFRQSLIDSNNVLESWDPTLVNPCTWYHVTCNVQNSVVRVDLGKAGLSGTLVPQLGLLSNLQYLELYSNDLSGVIPVELGNLTALASLDLYQNNLNGTIPDSLGQLSNLRFLRLNDNSFTGNIPVSLSTITGLQELYLSRNNFTGQAPDFYNLSKLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5Q6</accession>
    <name>A0A8T0I5Q6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G198400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5Q6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="166"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="255"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="166"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="44621" checksum="561D74E0F57D963E" modified="2022-10-12" version="1">MEAASMPWFIHFMRLNSRGLTPTVTMTEDMPSRVAVAQFLGPKHRSGYIFDDQGMPEYESYVRELFRRVLQLPWPVSNTMPFHFARGMLAEAMGVEMNWAEFAYRSTHPHQSNARFPRVLLEFEEITEPLEPLIVVMPRVNIEGYSPLSKADSQNARRLLSNPQAHLIPTTSSPNASTARPKGLDMTGGRGKEKHIEMLPAERPSERGECSRKGNCTIDESAAMGLILLRPSFNGTVEAERQRFIAARHDIGKPLHNLRSEIAEDKDRLKFLERKVAEKISSYERASEEYGQARDLYAAARFDQGQPASRDQKTAMKRMTKIRENLIANCFANLEGANTRLASWEFKMKRQNERIAKQTTELQAAEKVYAEKLTILDNSLVHLEAVAIVLADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6G5</accession>
    <name>A0A8T0I6G5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G197600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6G5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="426" mass="48708" checksum="F7D2274FE56B1121" modified="2022-10-12" version="1">MSWSTNEDRRAACKMETCYLDPAIWQELPPLLVALIISKLPILKLIEVVQQCGRFIKQQVMDNPPELLRTHRSNECFFPIFNAPGSGWMSAFGVRYRNWSPMPELNFLPCNVKHVLTGAGGLLCVTSSQPQQYHEEVIKAQGLALKCKERLWMRLPPQPIIVICNPLTRDTQILPPLPGALKYTVAHMKTSACTSNYALYLAGWDEKADAMVVTVYNSKSQAWMGWRSLPNGMRPTQVTSPGESSCVVLNDELWLAGEIRWAGIWEPRILCFDFITQNWKCELHWLPTCEPPRIVEADDCLYAVTRLSEKPYTLHIFEIIGTCEKTCLYSNFEEIARMPQSIHCNFFEIDVRRTRPGLVRWECRAGRGFIFFHNIVSGRLAWYHARAAMKGRENCWGMTNESAPKFESGYTSMVNCIWQPSFAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7A0</accession>
    <name>A0A8T0I7A0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Expansin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G018700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Secreted</location>
            <location evidence="6">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the expansin family. Expansin A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7A0"/>
    <dbReference type="OrthoDB" id="5823761at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009664">
        <property type="term" value="P:plant-type cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22274">
        <property type="entry name" value="DPBB_EXPA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.760:FF:000001">
        <property type="entry name" value="Expansin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.760">
        <property type="entry name" value="Expansin, cellulose-binding-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007118">
        <property type="entry name" value="Expan_Lol_pI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002963">
        <property type="entry name" value="Expansin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007112">
        <property type="entry name" value="Expansin/allergen_DPBB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007117">
        <property type="entry name" value="Expansin_CBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036749">
        <property type="entry name" value="Expansin_CBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009009">
        <property type="entry name" value="RlpA-like_DPBB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31867">
        <property type="entry name" value="EXPANSIN-A15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03330">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01357">
        <property type="entry name" value="Expansin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01226">
        <property type="entry name" value="EXPANSIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01225">
        <property type="entry name" value="EXPANSNFAMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00837">
        <property type="entry name" value="DPBB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49590">
        <property type="entry name" value="PHL pollen allergen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50843">
        <property type="entry name" value="EXPANSIN_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50842">
        <property type="entry name" value="EXPANSIN_EG45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035947751" description="Expansin" evidence="7">
        <location>
            <begin position="40"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like EG45" evidence="8">
        <location>
            <begin position="67"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Expansin-like CBD" evidence="9">
        <location>
            <begin position="189"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="274" mass="29977" checksum="91AC5EB6AC5BD504" modified="2022-10-12" version="1">MALRRLEPAMEGYDQHTKKSLTLILTALLLISTPENVDGRPHMRDGKSWRKAHATFYGGADASGTMGGACGYGNLHSTGYGLDTTALSTALFNNGAKCGACFAIQCYRSKYCLPGTPIITVTATNFCPPNRQGDGTPGWCNPPLRHFDLAQPSFVKVAKYRAGIVPVLFRRVPCQKKGGVRFTLNGNKYFNLVLVHNVGGKGDVRSVDIKGSDTEWMPMKRNWGMNWQTHTVMVGKALSFRVTTSDGVTVTSMDAAPPQWRFGQTFEGAQFNMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8G8</accession>
    <name>A0A8T0I8G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">sterol 3beta-glucosyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.173</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G045100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.173" evidence="2"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8G8"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016906">
        <property type="term" value="F:sterol 3-beta-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000009">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000030">
        <property type="entry name" value="Sterol 3-beta-glucosyltransferase UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010610">
        <property type="entry name" value="EryCIII-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050426">
        <property type="entry name" value="Glycosyltransferase_28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48050:SF13">
        <property type="entry name" value="STEROL 3-BETA-GLUCOSYLTRANSFERASE UGT80A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06722">
        <property type="entry name" value="EryCIII-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase family 28 N-terminal" evidence="8">
        <location>
            <begin position="396"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="domain" description="Erythromycin biosynthesis protein CIII-like C-terminal" evidence="9">
        <location>
            <begin position="695"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="851" mass="92869" checksum="12892256CA45D06E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8H0</accession>
    <name>A0A8T0I8H0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G140600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8H0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11688" checksum="8330E4ABA6487E04" modified="2022-10-12" version="1">MLTEAQKHTSTSKTWRKPLITHFQLMITCKKFRSHSCSKRESKINSTSAKKKPRALEAADIQSTESTTFKTRTKHSQRKFATKNCQISELQNEIYLKQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8Y0</accession>
    <name>A0A8T0I8Y0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G058600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8Y0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035825492" evidence="1">
        <location>
            <begin position="17"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9858" checksum="443E9EE9DEB739AE" modified="2022-10-12" version="1">MRGIVIFITFSLLALQEFERPYAVLVHSSPQQIRPVRFHSGGLSSRVVQMLRGFKCPKSKVAYLTQRMQHAECCSSLGLMASQCKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9U2</accession>
    <name>A0A8T0I9U2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G085200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9U2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013187">
        <property type="entry name" value="F-box-assoc_dom_typ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08268">
        <property type="entry name" value="FBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="16"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="424" mass="46973" checksum="8BE6C38B43EAC934" modified="2022-10-12" version="1">MGATTPPEQGEPVSTSDSWSRLPEDVVIRVLARLSVPQMFRARTVCKQWNSLTSTPEFVNMCGNGQYCEPYFPVVISRRFYMGDLGICILGNDEQGGNDLFRVFFGYDHSTGTWQRLPPLDFLPREARVPVAAAGGIICFRGTSSLFLCNPVAKTWVELPAITYKWPPSVSVHILVDQPSGSYKVIIVGKIRHNFVSDSFRSIAIYESTTKAWRVVDAQHPSKVFLYGPTAAICGGSVYCEAICHCGQLGVMAYDIQAEAWQKVLHEIPPDERGDYQLTQVVECGGSIYMVLARGFGGIVTGVYILKLEAPSSDTPHVEHDSSEHSRTTQQPPSKVWKEVTNLCEELLEDLRNQWFGDDDADIVCVGHGTRICISAGVNLILVYDVKTGLWSKVPTCSQLFDLGVNFSAEPIHFPIELRLKSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE27</accession>
    <name>A0A8T0IE27_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lipoyl synthase, mitochondrial</fullName>
            <ecNumber evidence="10">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Lipoate synthase</fullName>
            <shortName evidence="10">LS</shortName>
            <shortName evidence="10">Lip-syn</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lipoic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_4G230300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine + 4 H(+) = [[Fe-S] cluster scaffold protein] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 5'-deoxyadenosine + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="10">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="10"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01335">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000125">
        <property type="entry name" value="Lipoyl synthase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaA/NifB-like_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031691">
        <property type="entry name" value="LIAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058240">
        <property type="entry name" value="rSAM_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004019">
        <property type="entry name" value="PRK05481.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009544">
        <property type="entry name" value="PRK12928.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="LIPOYL SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949:SF0">
        <property type="entry name" value="LIPOYL SYNTHASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16881">
        <property type="entry name" value="LIAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01058">
        <property type="entry name" value="lipoyl_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102114">
        <property type="entry name" value="Radical SAM enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 10" id="KW-0408">Iron</keyword>
    <keyword evidence="7 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="11">
        <location>
            <begin position="137"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0581179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="43052" checksum="3539C3BA9D5A04EB" modified="2022-10-12" version="1">MKGGGRALGFSTVLRFTQQQGRGATILGQQQTRVSSTTNAPAEATATPALSALRERLAKGGPSLVDFITHSSTTPEGYSVEVGTKKNPKPKPDWMKMVVPGGDKYASIKSKLRELKLNTVCEEAKCPNIGECWTGGETGTATATIMILGDTCTRGCRFCAVKTSRAPPPADPEEPKRVAEAIVAWGLDYVVLTSVDRDDMDDQGSNHFAETVRNLKERKPSMLVEALVPDFRGDPECVERVATSGLDVFAHNIETVEELQSSVRDRRANFKQSLDVLRMAKKFAPPGTLTKTSIMLGCGESPAQVVKTMKSVREAGVDVMTLGQYMRPTKRHMPVSEFVTPEAFEEYRKLGVELGFRYVASGPMVRSSYKAGEYFIKSMIDEDRERQKIAAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IED3</accession>
    <name>A0A8T0IED3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G236000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IED3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9639" checksum="3520F1E023877E87" modified="2022-10-12" version="1">MNIDISEQHVCAVESFFCSNLSTDRQLINGLHKVCLNSIQVTSHCITTSLSSQLTNHPLVTFSQPLMQNEMINTSGTRKGVLSEVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGY3</accession>
    <name>A0A8T0IGY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chlororespiratory reduction31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G104500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021659">
        <property type="entry name" value="NdhS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35494">
        <property type="entry name" value="NAD(P)H-QUINONE OXIDOREDUCTASE SUBUNIT S, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35494:SF1">
        <property type="entry name" value="NAD(P)H-QUINONE OXIDOREDUCTASE SUBUNIT S, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11623">
        <property type="entry name" value="NdhS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="25991" checksum="69506DBB544B8920" modified="2022-10-12" version="1">MAAMTGICRPLALASQRESSFWGTNLCALPRVSSGNSQSLGRVAIRAEGFDLWQVLGGRGLKGGEDGLRREKTVKVLEEAKRNVVVEKKKKGTVEGNIAAAEGLPGTFDKELGGWTGGFPGGEKGLRQFVETNPPPAKVSSELQKLRESVVSPAKPKATSPPLLMPGMTVIVNSPKNPYHDFSGIVQRVTDGKAGVLFEGGNWDKLVSFRLQELERTSQGPPMSHPKSAILERMVVPDGNSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIC3</accession>
    <name>A0A8T0IIC3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentacotripeptide-repeat region of PRORP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G143500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000530">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein At1g74850, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="293"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="328"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="363"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="399"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="434"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="469"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="504"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="539"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="574"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="609"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="644"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="679"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="131"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="772" mass="85231" checksum="397EBA3051EFC5FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKY3</accession>
    <name>A0A8T0IKY3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G154900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008094">
        <property type="term" value="F:ATP-dependent activity, acting on DNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16509">
        <property type="entry name" value="RING-HC_HLTF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014905">
        <property type="entry name" value="HIRAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050628">
        <property type="entry name" value="SNF2_RAD54_helicase_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626:SF17">
        <property type="entry name" value="HELICASE-LIKE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45626">
        <property type="entry name" value="TRANSCRIPTION TERMINATION FACTOR 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08797">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00910">
        <property type="entry name" value="HIRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="252"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="617"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="689"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="306"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0583685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="862" mass="96097" checksum="CD3CC45A884E4B22" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INV1</accession>
    <name>A0A8T0INV1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G214200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042977">
        <property type="entry name" value="AtJ6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056453">
        <property type="entry name" value="HTH_DNAJC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44916">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44916:SF1">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23302">
        <property type="entry name" value="HTH_DNAJC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="296"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="307" mass="34791" checksum="F79FECAD9752C088" modified="2022-10-12" version="1">MGRKKRVREEDEETAAEEQPDTSESRSLYEVLGVDRNASHEEIRRAYHKSALRLHPDKNPGDENAKEKFQQLQNVMAILGDPEKRELYDQTGSIDAADIDGDAVKSLYKFLRTLFKTVTEDDIDVFSASYRGSKEEEKDLVTLYTKFKGDFKKVFNQMMCSDPQLDSHRFMDIIDAAISSGELKEYKTYRKWASEVSKTPRHPNPLAPPKKKKKNGDSTAELTALINHRGKKQMDSLAATLAAKYGNKGKGVKGGKSSKTTEEPSEEEFLAAQMRVMKSSKSVEEPSEEEFLAAQKRVRKKSKRSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPM6</accession>
    <name>A0A8T0IPM6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G248600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035714336" evidence="1">
        <location>
            <begin position="23"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15618" checksum="84BDED9E8C3803E2" modified="2022-10-12" version="1">MLIGLSSWVITLINLIPARVSLCPVTQCLPNPHIQKVNSFNEVHRRDSTVLEKRKQSCPLGDLDAMEARHEEDVGMARQKARPLSLQKKYSGMDVSQTIPLVLPIRLAAHSRAPLSVELAINWLCARFHSRAFVIELKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR77</accession>
    <name>A0A8T0IR77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G260800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37201">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37201:SF1">
        <property type="entry name" value="WD REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="411" mass="45775" checksum="5BA6FB6D0AA63496" modified="2022-10-12" version="1">MAMAVSSQIRVSVYLAHGVTVPLSPRRQAHVSLKLHLPVGGYLDLSRRSSYRLPMVCQSTNGNGKPWNGNSNGSSESLPAYEAFDQAAGVKPLGEGWDPWKQSSRSSSSSSGAGKADTSVRNPGGETSGRDDGDLGFRKIGSKYGPVGNEGEEPFRILPDGRKAYVDELDVLTLLVPPPFLKPMSNVKYNHAAFLWKKIAAIPEERRHRLLDLLEPRHITAMWKMAELRYDDPGLYLPNASRFLHSPSADPFQPIFWTGQVNEVPWVLNWLSRFKKAFFYSGDRELFGRVITGGPWLEGLGRKVAPLYFRVRPIKTVAATNEQCDFAFSYDDGHFELRNAVPDGFPQPGKHPWPFGKEFFDYVRVVGPGVVVGQSWYGSMSKSQDPKNPGVAPRKYLGEFVLIQNYENNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRM4</accession>
    <name>A0A8T0IRM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peroxisomal ATPase PEX6</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Peroxin-6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G029300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016558">
        <property type="term" value="P:protein import into peroxisome matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd19527">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000109">
        <property type="entry name" value="Peroxisomal biogenesis factor 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050168">
        <property type="entry name" value="AAA_ATPase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047533">
        <property type="entry name" value="RecA-like_PEX6_r2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077">
        <property type="entry name" value="AAA-FAMILY ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23077:SF9">
        <property type="entry name" value="PEROXISOMAL ATPASE PEX6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0962">Peroxisome biogenesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="408"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="785"/>
            <end position="924"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00034920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0585679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1038" mass="112507" checksum="B0811AE2FDFB2F0B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRQ8</accession>
    <name>A0A8T0IRQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Aurora kinase</fullName>
            <ecNumber evidence="13">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_2G015000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="13"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14007">
        <property type="entry name" value="STKc_Aurora"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000042">
        <property type="entry name" value="Aurora kinase A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000235">
        <property type="entry name" value="Serine/threonine-protein kinase ark1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 9 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="29"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="107"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="156"/>
            <end position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="10">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU367134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0585481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="33810" checksum="166629326FE5C426" modified="2022-10-12" version="1">MGSDAKLERQDSQNEGANRGEKRWSLTDFDIGKPLGRGKFGNVYLAREKQSKYVVALKVLFKNQLQQSQVEHQLRREIEIQSHLRHPNILRLYGYFYDQARVYLILEYAAKGELYKELQRCKVFNEKRAATYIASLARALIYCHEKHVIHRDIKPENLLIGLKGELKIADFGWSVHTCNRRRTLCGTLDYLPPEMVEGKEHDAGVDVWSLGILCFEFLYGTPPFEAKKHSDTYKRIVRVDLKFPSKPVISASARDLICQLLVKDSAQRLPLQKVLTHPWIVNNADPSGVYSGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISS2</accession>
    <name>A0A8T0ISS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G032600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="22566" checksum="B6A7ACAD6C6E4F60" modified="2022-10-12" version="1">MALSASSSCTQTVRNLAVTEASVSRGHEGKSHAGGVLPLPVKPKFQSSALQRTKSRKPVKVTKVTASAQDAAGAIDQSTESVITKAVSKVGDEIATKSEEILDAVDAVIEEGPAAMRVRKSGGKTNSRTSRRRALVMCLALGMVRPCASNVADNMQASTDLRRTASAMPALRRTESSSFKAPSTLVSQVSLATTLKQTNLLGEQEDLQKLTTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITG8</accession>
    <name>A0A8T0ITG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-[acyl-carrier-protein] hydrolase</fullName>
            <ecNumber evidence="11">3.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G086500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Plays an essential role in chain termination during de novo fatty acid synthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Plastid</location>
            <location evidence="1 11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the acyl-ACP thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.-" evidence="11"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:fatty acyl-[ACP] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00586">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.129.10">
        <property type="entry name" value="Hotdog Thioesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049427">
        <property type="entry name" value="Acyl-ACP_TE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase_NHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045023">
        <property type="entry name" value="FATA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727:SF21">
        <property type="entry name" value="ACYL-[ACYL-CARRIER-PROTEIN] HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727">
        <property type="entry name" value="OLEOYL-ACYL CARRIER PROTEIN THIOESTERASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20791">
        <property type="entry name" value="Acyl-ACP_TE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="Thioesterase/thiol ester dehydrase-isomerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10 11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 11" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-ACP thioesterase N-terminal hotdog" evidence="12">
        <location>
            <begin position="120"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-ACP thioesterase-like C-terminal" evidence="13">
        <location>
            <begin position="279"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF20791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0586385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="43745" checksum="4C32A4AE436298C5" modified="2022-10-12" version="1">MAGGSALAQQQQRGVCVGGVVAEGRGWRGERGGSGEVRLGLSSSWQGRRLQCGRRRAMEVVVRGSGSRATRAVTEEMQAECSAAEVQNGAYVLPAAVPSVSGNSPANEHIGYGEVFESNFYRERFVVRFSEVGDRKTMSLEGLASLMQEAACNHVLKVGYGAFAGTNGRVVTVTTRMHIEVDRYPVWRDLLEVDTWYCTEGRNAVRRDWTVKDVETGEIIAMATSTWVLMNMDTKAMVRINDQIRSEFAPWARDPPKWALSEDRIKASSARIPKINGDAEFSKTGLSPTERDLDMNQHVNNVKYISWTMESLPFEFRESHEIRKITLEYRREAQKGDTVESRAKAEPLIADGATFAGYTEEPSEERFVHVIRNQDGQEVNKGRTVWARLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXR7</accession>
    <name>A0A8T0IXR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="6">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">KC19_2G168400</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
            <location evidence="4">Cytoskeleton</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="6"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07830">
        <property type="entry name" value="STKc_MAK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000104">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000071">
        <property type="entry name" value="serine/threonine-protein kinase MAK isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050117">
        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 21 22" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="18" id="KW-0966">Cell projection</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="16" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 21 22" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 22" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="24">
        <location>
            <begin position="4"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="23">
        <location>
            <begin position="343"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0587491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="437" mass="49314" checksum="8D81420A7B24BAD5" modified="2022-10-12" version="1">MERYKVMRQLGDGTYGSVWKAINNDTNEVVAIKKMKRKFYSWDECMNLREVKSLRKLNHPNIVKLKEVIRENDELFFVFEYMEYNLYQLIKDKDKPFSEAKVRNWAFQILQALEYMHKHGYFHRDLKPENLLVTKDVIKVADFGLAREVRSCPPYTDYVSTRWYRAPEVLLQSPTYCAAIDVWAVGAIMAELFTLRPLFPGASEVDEIYRICAVIGSPSHHTWSDGMKLAASLNFQFPQLSSTHLSQLIPNASPEAIDLISSMCVWDPTKRPTASQALQHPFFQVHKRVPLPTPGCELVQPKSFIPTVIKANSMANKEFEGHAGLKRGNALWTKQGNSIPYANGKARPAVNRPSITPVGPPLTLGRGSATPAVKPTMAALPTRCYVHPAILSSTAPYARPQMPGGDTYQQAFHALPVVTANHRRGYNMRSSYNATVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYZ8</accession>
    <name>A0A8T0IYZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G204300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in sequestration of excess metal in the cytoplasm into vacuoles to maintain metal homeostasis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Vacuole membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000023">
        <property type="entry name" value="Metal tolerance protein C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000008">
        <property type="entry name" value="Metal tolerance protein C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF15">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="9">
        <location>
            <begin position="201"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="10">
        <location>
            <begin position="436"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="535"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0587956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="710" mass="76657" checksum="43918C328051FCCF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZY8</accession>
    <name>A0A8T0IZY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G234700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11143" checksum="8A2A5A13154E508C" modified="2022-10-12" version="1" fragment="single">GNPKNSIELGDLQPRWRTPLEGRADEDIATPSCVTKNSQKTFNKNRKPKTHTNPKTLNPTTTPNSARERGFRKLCETEAVYGFIRDAHPESTHLSVTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0G4</accession>
    <name>A0A8T0J0G4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G021500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035749156" evidence="1">
        <location>
            <begin position="21"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6438" checksum="DC9AAE36E9060D3B" modified="2022-10-12" version="1">MQQLMKFLGMTGILMKELLSFLLQQNKWVHCGSDYRTRFPALLKITVCRYIDIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J141</accession>
    <name>A0A8T0J141_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G038700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J141"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6887" checksum="856AA89B6BCD59E9" modified="2022-10-12" version="1">MNIQEYCAGSLALFHAISSRLSLRVLVHRHSLQVIHVVSYLRLTFEQTEFHAYKENIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J293</accession>
    <name>A0A8T0J293_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G290100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J293"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035871151" evidence="1">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="7213" checksum="145F3EAE2E283CE8" modified="2022-10-12" version="1">MTKRAAWRLCWHIRVLVAFLGRNPEKKFSQTKPQKKYIAKLQTEKFEKGFRSVVGATSSSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3X1</accession>
    <name>A0A8T0J3X1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G087500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3X1"/>
    <dbReference type="OrthoDB" id="2020529at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34572">
        <property type="entry name" value="GOLGIN FAMILY A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34572:SF1">
        <property type="entry name" value="GOLGIN FAMILY A PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="197" mass="20874" checksum="64686B670768E32B" modified="2022-10-12" version="1">MEGGLGSTRMGSRSSTRHGPASVFQGRVRRWKKAWAPVAPSTTPSAAACRVLLYKWTPVTVPTTNGAKESTPEEPPPAKPLRFLPVSVVLQQKKEEALKAAEEAEAMARSLQKESESATNATVETDEADAKDTQEDTNMGGTQPEETGATASETNDEAVEGDAQTTRAELAASLQDESTAAPQEPEAASMDVDQSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5D2</accession>
    <name>A0A8T0J5D2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G063100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5D2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="454" mass="49522" checksum="DF886236A2E131A4" modified="2022-10-12" version="1">MVPLPVTTTGKSASISEPVEYGEPALEPERIRNTETSNEGARRGMCNTDNPVNPIPRGHAEQDVAATDNLYRLGDTTNIILHRQQQVEKDVAYLKDSVSEILDQFKGFQSLPTILGQVQSLLSGRRQDQEGDKDNGVKISEQNSFDSSNLGGGGVMVSPSPAVHILRSNPLKTTEDSANCDDDLPDQSKNVDNGTHICVHMATETTTKIKGINDPVPSLDRDAGFNPNEKEVAHTIEISATARPAEELHMQANSEAATKTVSSSNIVASNSLHTQSQLVDIQKEGTVTPYSEEGTVVVEPNRKPTPQSSDPSIQTVRKKSKFEERAPPATLTPNGHQRGYPMGVNKDVWVIHPTRGGGPVALGKTGYSFKTTKAKLQASPWRSLKWEVGMQLVEIKKVYQTGVKVMHPTQQPQKNVKTLDDVTDVEFSDDALVMWGSDYLVEVSAAAKKKKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5X1</accession>
    <name>A0A8T0J5X1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G140800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5X1"/>
    <dbReference type="OrthoDB" id="10483050at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005818">
        <property type="entry name" value="Histone_H1/H5_H15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00538">
        <property type="entry name" value="Linker_histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00526">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51504">
        <property type="entry name" value="H15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="H15" evidence="2">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="17156" checksum="B1A3FEBBAF1A0F68" modified="2022-10-12" version="1">MAAGQALVREAMTHLKMRKGASVAQIRQQIQSNYSGKIDVQKRGVLTTALKGLLEKGQVEKKGPNYKLAEVSKLKNDEEEMGVPGRHHRRRRHHGGGGRRRHHKRRRHHRRRSRHRRRGRRHHRRRRGHHRRRRHSRRRRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6E6</accession>
    <name>A0A8T0J6E6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_1G179700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6E6"/>
    <dbReference type="OrthoDB" id="543156at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000468">
        <property type="entry name" value="PTI1-like tyrosine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000420">
        <property type="entry name" value="Putative receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043891">
        <property type="entry name" value="SPARK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989">
        <property type="entry name" value="OS01G0750732 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47989:SF36">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19160">
        <property type="entry name" value="SPARK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274576" description="Protein kinase domain-containing protein" evidence="15">
        <location>
            <begin position="27"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="257"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="331"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0591500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="645" mass="71568" checksum="77C09E42FCEE0D93" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J715</accession>
    <name>A0A8T0J715_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G175300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J715"/>
    <dbReference type="OrthoDB" id="2355at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002060">
        <property type="entry name" value="PRK00892.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378:SF2">
        <property type="entry name" value="UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0591427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="324" mass="33995" checksum="D1C63863759E6201" modified="2022-10-12" version="1">MTRVTALIRQALWTHPLPGAAPAALLNHVTRQRGFGGGALYSCVGIRVRVLATGFRAKSTVQGIRCEVEEAESEYVRWRSGGGTVHSLAEVHSSVVVEHGALVESKAQVGANARISAGCVVGPGVFVGESTTLGYNVVLQNCSVGASCTLHPGVCVGQDGFGFLENSSGEIVKKPQLLRVQIGSHVEIGANTCIDRGSWRDTVIGDYTKIDNLVQIGHNAAIGRGCMLCGQVGIAGSATIGDYVVIGGKAGVSDHVTVASRVRIAAKSGVMSNIDKPGDYAGFPAVPAREWRKQMVVLRRMGRPAVKELSLEDGEGEVPAGEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J962</accession>
    <name>A0A8T0J962_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G252900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J962"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000056">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035595">
        <property type="entry name" value="UDP_glycos_trans_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00375">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0592454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="525" mass="58152" checksum="75295819896CDBFE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9I6</accession>
    <name>A0A8T0J9I6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G188800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10247" checksum="FCB12D17C904371C" modified="2022-10-12" version="1" fragment="single">GWDLVERARESIEVFSESSASKVCTDCLRVFLVTAGLRTSLAIPDDCSLSWDCSSSLSTACLRTFIQLEGEKNKTNTKLGIPRPTIARDYEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAJ9</accession>
    <name>A0A8T0JAJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Kinesin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G215900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF62">
        <property type="entry name" value="KINESIN FAMILY MEMBER 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 7 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="13"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="99"/>
            <end position="106"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0591979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="44698" checksum="9B62B53640D5E0E7" modified="2022-10-12" version="1">MPFEFANEEPLSRVKVYVRLRPVQKPSPMIHVDDETGTVIVDVLKSSGGGPPRSTIEQSAFTVDDIIRTTNQQRAFEHCAKEYTDEFLNGYNATIMAFGQVGAGKTYTMAGDTKIHVHRGFIQRAIGQVMEEKRAHPEAGIVVYMSYLEIYEERMYDLLQQRSTDLMIIEENGLIDIRGLAKIRVETEAQAIKWFNEGEKQRSYGQHLLNQQSSRSHTFFTLYMERRVGRFHTEHDTIVAKLTLVDLAGAERLKKTNVERGGRMRKEACTINKSISYLETAIYALRVGQNYVPFRQGKASTLLKESLGGNCKTMIMICLWLEDCFYDETVNSLRFAQKVKFLKTYPFRNKKLDCATATKRRHLQQIANLQQEVALKDALQGRPGLSFDDLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCF8</accession>
    <name>A0A8T0JCF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G248300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0592391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="561" mass="60476" checksum="EEAFCC6404CBE3B5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5D6</accession>
    <name>A0A8T0G5D6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G063500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5D6"/>
    <dbReference type="OrthoDB" id="1932122at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35312">
        <property type="entry name" value="OS07G0641800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35312:SF1">
        <property type="entry name" value="OS07G0641800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="14555" checksum="39C86B1FE4EF6069" modified="2022-10-12" version="1">MEEEQFQRLLELFPVVRTSSYCADEVNGMNRRVPSGLPSSTVQLQPVDTGSPSQEIDTGKGIQSPPTSVASLGDEANFWDLLKTAAEKQLSPENAQRFCDTFKARHNDLVNNTLSLDAIERIAKHWPLPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G689</accession>
    <name>A0A8T0G689_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G006900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G689"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="185" mass="20417" checksum="A0D5494504D753FF" modified="2022-10-12" version="1">MNRGNINAFRYSMRLRGLKHGSEEEYDMFEDFAVCRFRNGRMNGAADSKLQLEHRTPVASGEDGDGDGATIRAAIAQHTIGDANEHLATEDTSRCTEDGKRSLEKDINANHLKTAQKNYEVKEISNPVGHRPHVDNHVCTQAEESIQPDPSTSRNSAVSQITVHMKCGKPAVYNDPLRAGAEALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBA2</accession>
    <name>A0A8T0GBA2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G145700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021475">
        <property type="entry name" value="Pants/Emi1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28052:SF1">
        <property type="entry name" value="UPF0545 PROTEIN C22ORF39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11326">
        <property type="entry name" value="PANTS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="13097" checksum="F9C3959E3AB29453" modified="2022-10-12" version="1">MGEEALQLQQGDETAKPAVKPKVSCVPKADALWFCYSPVYQMTEYYRQGTFDNCRSKWTELFDCLSLKTKPADQIQAILEERERKKPHIWEFRTPEEASKHWKEEFGHLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCW0</accession>
    <name>A0A8T0GCW0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G113300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12781" checksum="BB318DDC2B23B58E" modified="2022-10-12" version="1" fragment="single">SSPLRGTTQLLLINLEQIRPQKLTPHLHYGSSHTLEQDPKMATRKPGPPSSNPHLRLQITNIRETVHSQIRDGSSNQKLHTTVLLIEILEHRSAKGETNTHLSHRSDAPLLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDJ7</accession>
    <name>A0A8T0GDJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G078200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="446" mass="50238" checksum="7FBDA6DD61B81162" modified="2022-10-12" version="1">MSKLFACWLSGAVRPNQANQASQSLNNAAVLIQAINQAASHFSGQLNLNEQVERARAFNTVKLLQDSILDPEEEEDFTPGLKHQRPASPLDYTLDIDYTAAKVVNSVIEKCKLFLLVTSLYNDGCHELLIILQGLHNILTVVQGSACLDRYKDVLEEILLYSTKAFAFIDKVYLQAMPNTLQLVPGCKTSAKFSEFACRFYNLKVELYEQYERSDNDILLCVSPREERLSYGVTTYSVPLHNLARRLYKKKRVVIPLTEVNGKSRYEVELTYPRTWRSDNVGLTSRVESSDHGYSKTLQGERVQIEKGGWGWEAAQDTVLITYDDLLVANVASIAGSLLTFNKDGVKDDKTCSMQTFRTSIQVVGSSRIDSDLQNLFVKGTKDKDNVYLKCFVTTDGEEVLAIYRYHRQHFHRAEGLLHIIGRGNQPGLRHVLISIFSSLGFTSVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDQ0</accession>
    <name>A0A8T0GDQ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G106300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31241">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31241:SF62">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="10">
        <location>
            <begin position="46"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="232"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="193"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0557153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="35280" checksum="395CCB054EEC5C83" modified="2022-10-12" version="1">MHLSSQGDGRLSPNSGHIEKPPRKPGKRWKKGSMKGKGGPENAACEFRGVRQRTWGKWVAEIREPKKRARLWLGSFSTAKEAALAYDIAARKLYGPLAELNLPPQESLGLDSVPTSTPSGSPPRTMYDVEITEQREIPQAAGSSSFTSMHIGIKEDEFDEELVMTIPRSGRASTSFDTREVFLQQETFRDSRPTSSSSQFYQGEQAELSSQGEHLNDLRDIEAFLDQIDFNHPTSSTFSMDDDNLSGSNSSLSPSLESSAPGSYPVDGHWEDENLGNQFINLELQSLESVLNEPLVPESVELWDTPTSLPPSSHADPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE81</accession>
    <name>A0A8T0GE81_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G152000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035869696" evidence="2">
        <location>
            <begin position="24"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9923" checksum="A3D8754679C68C78" modified="2022-10-12" version="1">MAFIKYVLIFLISIFMLQSTINAQRGPFQNGRSPRIFNGTNPFPFPTNGNNPFPLTNNGTNPFLAPNNTSSPFPPRRRGGGRRGGPTTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ43</accession>
    <name>A0A8T0GJ43_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G155000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9642" checksum="D2A13E47D2C1EAD7" modified="2022-10-12" version="1">MCSYTCDGCMIKVPDCWPSGAIPHLALALKVGLIRMDVQGLSDMNHVGDGLFEHEWRFVQSFWDWYPMLLGCLVSVLIGFSLALVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKF2</accession>
    <name>A0A8T0GKF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ER lumen protein-retaining receptor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G074400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERD2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKF2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046923">
        <property type="term" value="F:ER retention sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006621">
        <property type="term" value="P:protein retention in ER lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000133">
        <property type="entry name" value="ER_ret_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10585">
        <property type="entry name" value="ER LUMEN PROTEIN RETAINING RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00810">
        <property type="entry name" value="ER_lumen_recept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00660">
        <property type="entry name" value="ERLUMENR"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00951">
        <property type="entry name" value="ER_LUMEN_RECEPTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="25664" checksum="7B86EA2C3916DB83" modified="2022-10-12" version="1">MNIFRLAGDLTHLMSIVVLLLKIHTIKSCAGVSLKTQELYALVFVTRYLDIFVTFVSFYNTVMKLIFLGTSFSIVWYMRYQKTVRASYDKNNDTFRHYLLILPCFALSLLINNRFTFREIMWTFSLYLEAVAIIPQLVLLQRTRNVDNLTGNYVFFLGAYRGLYLVNWIYRYFTEPHYHQWITWIAGIVQTALYADFFYYYFQSWKNNEKLKLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMA0</accession>
    <name>A0A8T0GMA0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G060400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMA0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000157">
        <property type="entry name" value="Hsp70-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000357">
        <property type="entry name" value="HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050693">
        <property type="entry name" value="Hsp70_NEF-Inhibitors"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316:SF18">
        <property type="entry name" value="HSP70-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19316">
        <property type="entry name" value="PROTEIN FOLDING REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02985">
        <property type="entry name" value="HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="28952" checksum="730BF262FC8F14A0" modified="2022-10-12" version="1">MLVSRARAAEVVSTVVQNNSKSQQQVIECNGLENLLINFNFDDDMKVRTKAFGAISSLIRHNKIATDAFRLSNGYAGLREALASGDLRFQRNALQVMQYLLQENPKDHSVATQLGFLRSLTSLANSSDLDVRQAALQALVEIVRHQDTLSPGKFDDTTHLKDVVTRRVEEIKGLNQEDLAAVKEERQLVDTLWQLLYKEPSELRQEGLLVLPEDNQLPPDVASRQFEPGLQSLSAGAPSEPPTEQNRSQETKQPVLLLGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMJ1</accession>
    <name>A0A8T0GMJ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G104800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMJ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11393">
        <property type="entry name" value="bHLH_AtbHLH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054502">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045239">
        <property type="entry name" value="bHLH95_bHLH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052610">
        <property type="entry name" value="bHLH_transcription_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45959:SF63">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45959">
        <property type="entry name" value="BHLH TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22754">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="237"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0559439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="467" mass="50109" checksum="8421A80FCCB254B2" modified="2022-10-12" version="1">MEQRRIGHAHQTPPPPPSSSLLGIGEELYELLQGNTRSTQSSNSTAKCITNPSPASPLFFDHIPKMEPELGDFMGSSYTWGAPATQLYNVASVDSLACLTNYTTPNTTHLTPLPDVTSQFAYTPAPAPGAAGTASPQIQALRDFMVYGNLAAGPGTMGSMPAMPSPTMTSFSSAVSSRSTTPVATNGGMGFYQLDDVGVADAGMLAGAPKAQDMSLAYRALCSEIYATERSPHRSQFQRENHILAERQRREEMNEKFSALRAMIPKATKKDKASIVGDTIDYVLELEKRLKQLQACKDTASGTGFFKSLKRKSPYGSRGGGEDGALESPKPGGSSSETTHQRDPGSPSPIRESRDSAVSSPSDQITEESKLPGKTKGGVAEVDVQMLGKQAVVKVVCSRQPGHVLRVLNALEECKVEVLQSNVMTVADNSIHFITVQVQRNFWVSAMTSKATTCSDHLSFGARDLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMZ6</accession>
    <name>A0A8T0GMZ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G178400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47468">
        <property type="entry name" value="OS08G0130000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47468:SF1">
        <property type="entry name" value="OS08G0130000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="CorA soluble domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="411"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0560400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="52300" checksum="DD2E1EE641C86291" modified="2022-10-12" version="1">MANFASRSLSRIVPVLRKGGSGSESDMDGIGEHGVRSFYEDEQPRLHFPGAVRKFAYRFDGNGKFVKKEWDLMKDQQEGFCWYHVELPRSSQKLSTSAEYLIDVLCPPLKLQEILALVSSGPFCGTVDGALVFRVNSAGPCGSKFTQRISAIVTDKRIISVSLGRVSRLDFSAASTRSLLSEVPCIEPKDQSNGEGISHLGTTKSGGVVIQEHVLEFLLSRNTFEEAENVIPMGVGNLLVHIIDTHVDQLHEIVLQLETQLDEVERDLDLGVGATKKQMLDDRRFPKMHLNLQRLLQVIAHGDQVFPRVKEKCVGKSWCSQEDLATLDALVGRLRKLKENVGFIVSRITAIQAGLDSWQAEQINRKLYYLSFLSMMFLPLSIVTGAFGMNVGGVPWTTQTNPKISHGFRNVMLICAAIVIILLVIFGAVPLYNFLISGRRQGAKDKRLRYQKSIRYRGGSQRHPAYLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNV9</accession>
    <name>A0A8T0GNV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dehydrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G136800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="512"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="575" mass="60622" checksum="9C4B61A8C79384E6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ29</accession>
    <name>A0A8T0GQ29_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G177300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035757907" evidence="1">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5909" checksum="A16C38136D2953B1" modified="2022-10-12" version="1">MLTDFSCDSHHTWFCFLIFLVRRGLAGILEEELNSGFTTGQCEFVWGSGSYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ69</accession>
    <name>A0A8T0GQ69_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G034500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12350" checksum="2880EAB7906A3B04" modified="2022-10-12" version="1">MSIVQLFPSPFIRFNLLVALLAVRYISHLLVTNPLIMLKFASTKFYLNGALFSMFVWFVEVSNILSCIWFVDTSYLYFPGIYNYLRKHMYDTFFGCILYLFVVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ93</accession>
    <name>A0A8T0GQ93_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G181400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ93"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="12165" checksum="71AAD84C5C0E176A" modified="2022-10-12" version="1">MDKVLVYTHLSIASTVNPQRQRIPLKSVAYEPVECFGHVLFLVPESFGPDCQGGRHHRVWIRPVIRWLSESNPRQSFCSEPKLRYKLLLIYLRKAFNFQGLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQR1</accession>
    <name>A0A8T0GQR1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutamine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutaminyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_9G013000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>tRNA(Gln) + L-glutamine + ATP = L-glutaminyl-tRNA(Gln) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00807">
        <property type="entry name" value="GlnRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000007">
        <property type="entry name" value="Glutamine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2420:FF:000001">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1290:FF:000002">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.240.10:FF:000011">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000037">
        <property type="entry name" value="Glutamine--tRNA ligase cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.1290">
        <property type="entry name" value="Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="entry name" value="Ribosomal Protein L25, Chain P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007639">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042558">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042559">
        <property type="entry name" value="Gln-tRNA-synth_Ib_RNA-bd_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050132">
        <property type="entry name" value="Gln/Glu-tRNA_Ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_bL25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_bL25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049437">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097:SF4">
        <property type="entry name" value="GLUTAMINE--TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43097">
        <property type="entry name" value="GLUTAMINE-TRNA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20974">
        <property type="entry name" value="tRNA-synt_1c_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04558">
        <property type="entry name" value="tRNA_synt_1c_R1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="Ribosomal protein L25-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaminyl-tRNA synthetase class Ib non-specific RNA-binding" evidence="14">
        <location>
            <begin position="17"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic" evidence="12">
        <location>
            <begin position="278"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding" evidence="13">
        <location>
            <begin position="584"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA synthetases class I (E and Q) anti-codon binding" evidence="15">
        <location>
            <begin position="694"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF20974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0560785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="799" mass="90734" checksum="DBCF0FA04369F765" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRU7</accession>
    <name>A0A8T0GRU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">60S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G080800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.370.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008195">
        <property type="entry name" value="Ribosomal_eL34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038562">
        <property type="entry name" value="Ribosomal_eL34_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018065">
        <property type="entry name" value="Ribosomal_eL34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10759">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01199">
        <property type="entry name" value="Ribosomal_L34e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01250">
        <property type="entry name" value="RIBOSOMALL34"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01145">
        <property type="entry name" value="RIBOSOMAL_L34E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="121" mass="13849" checksum="A7FEAD902D57DEC3" modified="2022-10-12" version="1">MVQRLTYRRRHCYATKSNQTRVVKTPGGKLVFQTAKKRANGPKCPVTGKRIAGIPHLRPTEYKTSRLHRHRKTVNRAYGGNLAGSAVRERIIRAFLVEEQKIVKKVLKIQKSKEKMAAKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVZ5</accession>
    <name>A0A8T0GVZ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G036300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVZ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11678" checksum="9FAF51507A1BEE40" modified="2022-10-12" version="1">MEDKKMITNILKLGLLCCNPNAEDRPSTRLVSQLLLLQSCESMEMLMPPLPRSKPQARYDKPGFSRMLGMVSPSNSDLLDIRNVVEVSYATSEATTHLSALPNGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWS3</accession>
    <name>A0A8T0GWS3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G188400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11606" checksum="00632E045B55041F" modified="2022-10-12" version="1">MREHYSRTNRSGAFCTRSAEQLPSQPPASNPLGREPHVDTSKLNLACDRRGHRRSPRDAQPSTADFAASRKNLILSAVVSRPHSHQCIIIGKSNKLCTDCLRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX48</accession>
    <name>A0A8T0GX48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAR1 protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G045300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX48"/>
    <dbReference type="OrthoDB" id="772928at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009489">
        <property type="entry name" value="PAR1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33649">
        <property type="entry name" value="PAR1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33649:SF2">
        <property type="entry name" value="PAR1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06521">
        <property type="entry name" value="PAR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035755405" description="PAR1 protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="371" mass="38975" checksum="C12C76D72AD430ED" modified="2022-10-12" version="1">MAKLRQLSTIPLVLGLLFSNIVCTLGKFECEDLPIEDCAFSVASTGTRCVLEKYLGKDDSIQYECQSSIIIAENREEWIESDECIKACGLERMSVGLSTDLLLDYHFTEMFCSSECLNNCPNIIDLYISLAAGEGMYLPQLCKAHRTRRVIADPVKKAMDAEYIRSLLPQLTSGGAMAPNGSPIPENGGVPPGLLPRGPDYRGYGGYQGSPGDIPTSGGESAPSTSPVAGGNYQPGPLQRSAGAAMAPSSPSAGGDILPGPLQRSAGAGTPPSTPSAGAAGPSVNKRPFFFIPSSSPTAAASIQPIPGADGTTPEAGIVTPPESGISPSSIAKSESAPVPSEVFKPKELSAKLFNNQQVNDEEYLYETYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYS4</accession>
    <name>A0A8T0GYS4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PRLI-interacting factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G114800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYS4"/>
    <dbReference type="OrthoDB" id="1935617at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34484">
        <property type="entry name" value="OS02G0832600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34484:SF2">
        <property type="entry name" value="OS02G0832600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="255" mass="28798" checksum="77F39048BAA8F9BC" modified="2022-10-12" version="1">MGFPSKQRERDWLVVSLSPPDGKKRPWMRSTGPEWQNPTRFYPHPYAKRPLLPRRHKPRRKNKKSIMNRVPCAPYNTSSYLMRAGKLGVNAPLLSPATPALETPVVSPSPWPSESLGDCEVAKELGVNAYGSMNGRIRLRSDDMDRDSGSSSCGESDTEHCDRHPADSVQQVEERINHGLQRFEILYNADSPLRPHGVVSDEETHIQHLEEENLSLQQRLWAMSQELSHLRRRLGHDDEFGVVSDESLGNGSCAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ61</accession>
    <name>A0A8T0GZ61_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G063100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11422" checksum="BDCCEDD65DFB4EB3" modified="2022-10-12" version="1">MTNLKTSLGVTTDARVMPGFKFWSLLLVLRTQFQSEETARHEKNEQKSFNPDECTSIATRIAQPNHLRPRPAGCNTNVGNPNIVSISKEHLLDCADNNIWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZN4</accession>
    <name>A0A8T0GZN4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G165900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10522" checksum="D00A753BD7064041" modified="2022-10-12" version="1">MVCYEVLTGDVPFPEEKNPNNVKRMVLEGVRPDLPAHCPIEPKALITDCWNQDPLKRPSFAVICQKLKYLKYLLMTGFSSYQDSYPSTEEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZY1</accession>
    <name>A0A8T0GZY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal RNA small subunit methyltransferase G</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G075400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000041">
        <property type="entry name" value="Ribosomal RNA small subunit methyltransferase G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760:SF0">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0564005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="30944" checksum="3A2294D6F9A9E722" modified="2022-10-12" version="1">MASPGLMRIAFHRPRLTGFAISSRTLSGFRISPQQKHWWNARFHVNCSSVAAVEELSSRQSGQVAVFVDILLEWNQKMNLTAVTERGAMMDRHIADSLSLLPTIEGAYAAHCNGSEGGESVKVVDIGSGAGLPGIVLAIARPAWQLTLLESLQKRCDFLEHVAKEAGLTNVKVLRSRAEDAGKDIAHRETHDVAVARAVAEMRVLAELCLPLVRVGGILVAAKGPNPEEEVEAAKTAVNLLGASIVTLSRVDSQGPLGQRTAVVCLKDRPTPAKYPRRAGMPNKRPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H070</accession>
    <name>A0A8T0H070_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G083100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H070"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5623" checksum="E5ED4E1574635225" modified="2022-10-12" version="1">MKRMAIHAFITIQASRLLGFCNGPVLGIISKGFVRLGISQSFSYIINGTFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0R1</accession>
    <name>A0A8T0H0R1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G149100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0R1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7700" checksum="7A7CC2FB1A7877E2" modified="2022-10-12" version="1" fragment="single">PRNRSILQTNETVAPEGEFHIIFQLPSDSASNQNYNLVELILSLLELHSSLSSVHVWQANWKRELEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0U9</accession>
    <name>A0A8T0H0U9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G073500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0U9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="12"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="667" mass="75467" checksum="50FDBECAF3BD7BD5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3F9</accession>
    <name>A0A8T0H3F9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G180000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3F9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751300" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="9276" checksum="8F0E96724C3E002C" modified="2022-10-12" version="1">MWRMSSRLMNILFKLVLSRPPFLANRPPNLSTTDCFKLQQRATKGTLLLLTPTDIPILSHTRLNTLIQARRRIYARPSLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N4</accession>
    <name>A0A8T0H5N4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G008000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054722">
        <property type="entry name" value="PolX-like_BBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22936">
        <property type="entry name" value="Pol_BBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrovirus-related Pol polyprotein from transposon TNT 1-94-like beta-barrel" evidence="1">
        <location>
            <begin position="33"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF22936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17419" checksum="6801F43A8779E47D" modified="2022-10-12" version="1">MSEVKKKESFTHFAQVLAEGQSTENDDEVWYVSNASDHMTPKREWFTTFEEVPEGDWSVGELDGSQHWVRGRGNIKIQRKLGLQWEDGVLENVLYAPALRRNLFSLGRAVKQGNSASFGGTDCTLRNSEGAEMLTGTGHGGLFKLNVRVMPPELSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5T1</accession>
    <name>A0A8T0H5T1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G039600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TALE/BELL homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5T1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000117">
        <property type="entry name" value="BEL1-like homeodomain protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006563">
        <property type="entry name" value="POX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07526">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00574">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="611"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="613"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="415"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="682"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="426"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="682"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="739"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0566115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="802" mass="86740" checksum="371C547D521E20FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7J8</accession>
    <name>A0A8T0H7J8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Red chlorophyll catabolite reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G050300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7J8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051743">
        <property type="term" value="F:red chlorophyll catabolite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009439">
        <property type="entry name" value="RCC_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685:SF2">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06405">
        <property type="entry name" value="RCC_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="331" mass="35950" checksum="A85E755EC582FF9A" modified="2022-10-12" version="1">MHSYPRSAMACHARFSCAQTLPSSSLRCNPANQPGLRSGGVANLGLIRSRNTVRWGVRAAVSETMGSNETSWVEFPKLSSAGKQLMESVAVMMDRELGALIKDSKTPADVRSFQGGTGEGSVTLRAGRLGSKIDLVLGSWLNCSLSFGALNIATLIAMMGLTSDAPHLLFEFIQSGPDSLVLVLDLVPRTDLVVDPEYLARFYENSGLEDIRQTFEKHPQTQPHRPSALYLRSIVSPTALLYEISGEGVEGGLDAVIADLVQPAAVKVVQTWVKSFKYLGRAMDSDAMAYMKTRDDLIKRKGVEVDLSANMPRLFGQEIADRVVAAFRKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9V6</accession>
    <name>A0A8T0H9V6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF985 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G113600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9V6"/>
    <dbReference type="OrthoDB" id="6614653at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387:SF3">
        <property type="entry name" value="DUF985 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="RMLC-LIKE JELLY ROLL FOLD PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF985" evidence="1">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="189" mass="20949" checksum="DB00EC7FFC7CC26D" modified="2022-10-12" version="1">MATAQEICKLLELQPHPEGGFFAECFKDPDVNLPHSLLPATFKIGRSVSTAIYFLMPTGNVSCLHRIPSSEVWHFYKGDPLTVFEIDDEGNTKHTVLGQDIAAGQKLMYVQKPNVWFGAYPTKDIEHIPEAGKPIVKSAPRDPETNFSLVGCTVAPGFEFDDFVLATRSDMLAKFPHAKAFVEFLTHAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB10</accession>
    <name>A0A8T0HB10_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G185300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44137">
        <property type="entry name" value="BNAC03G44070D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44137:SF32">
        <property type="entry name" value="DNAJ HEAT SHOCK AMINO-TERMINAL DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="2">
        <location>
            <begin position="88"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="522"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="572"/>
            <end position="600"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="687" mass="77280" checksum="A1E5E6DE799589F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDS9</accession>
    <name>A0A8T0HDS9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G108500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="8417" checksum="D20DA4EAFC8CC1A3" modified="2022-10-12" version="1">MHSPQPQPSMQQPLHTWPDLFLTPTPTPTPTLISPSSGAPGTNLGSQGSEGSEGSGGSGGVSGPKFVKEVSNGGRCGEGAGVYPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH29</accession>
    <name>A0A8T0HH29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AUGMIN subunit 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G106000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH29"/>
    <dbReference type="OrthoDB" id="661220at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051011">
        <property type="term" value="F:microtubule minus-end binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029327">
        <property type="entry name" value="HAUS4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16219">
        <property type="entry name" value="AUGMIN SUBUNIT 4 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16219:SF1">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14735">
        <property type="entry name" value="HAUS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="429" mass="47972" checksum="410EE6863094F587" modified="2022-10-12" version="1">MVKAMLLPAPALPLGQGVPALLDQLERHCLAPDGTLVSKPAYLDLLQAREEMARERLRYLEAMAVYGEAVALVEEYQHAVSVANVGGIRDLNTVFDQLGLRSSPQVYDALEQRLVVAEATQRLRLPLLSKDGDLPEDDNQEWGNVSRSSFDSTTTSLSLSTTTTVHTTSASTASATIASGGGASQTEVVEPGVGGVVNRFLGITPAWLRQTHLIRAPFADDSTGYQITLMPEIEARLKSKCDRLVAAFESDETDNAGPHSSSLRLPERVKLAVEDIEAEEAALLEDLYAADRKFSEYYNVLEQILTVLLRLVKEFKLQHQHDYDGMRKQWLVKRCQTMNTKLRVLEHLLLRDTYTQESIPALHKIRQHLVEANEEATAAYNRAVTRLREYQGVDQDFDEIARRYLDLVTKLEGIQWTIRQVEMDLSNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHG0</accession>
    <name>A0A8T0HHG0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein decapping 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_6G107000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">As a component of the decapping complex, involved in the degradation of mRNAs. Promotes P-body formation. Translational repressor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LSM14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033962">
        <property type="term" value="P:P-body assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034063">
        <property type="term" value="P:stress granule assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01736">
        <property type="entry name" value="LSm14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000033">
        <property type="entry name" value="Trailer hitch, isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025762">
        <property type="entry name" value="DFDF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019050">
        <property type="entry name" value="FDF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025761">
        <property type="entry name" value="FFD_box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025609">
        <property type="entry name" value="Lsm14-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025768">
        <property type="entry name" value="TFG_box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586">
        <property type="entry name" value="SCD6 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13586:SF0">
        <property type="entry name" value="TRAILER HITCH, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09532">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12701">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01199">
        <property type="entry name" value="FDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01271">
        <property type="entry name" value="LSM14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51512">
        <property type="entry name" value="DFDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51513">
        <property type="entry name" value="FFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51536">
        <property type="entry name" value="TFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0678">Repressor</keyword>
    <feature type="domain" description="Sm" evidence="13">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DFDF" evidence="10">
        <location>
            <begin position="521"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="FFD box profile" evidence="11">
        <location>
            <begin position="587"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="TFG box profile" evidence="12">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="81"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="295"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="FFD box" evidence="7">
        <location>
            <begin position="587"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="TFG box" evidence="8">
        <location>
            <begin position="610"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="87"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="204"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="295"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="387"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="406"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="420"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="471"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00059323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0569679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="685" mass="69976" checksum="FEAD201E95DDDF66" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHH6</accession>
    <name>A0A8T0HHH6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G178100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12379" checksum="F596A2130428F9DF" modified="2022-10-12" version="1">MHLLLPRIVSLQTHHHLRITDTCELKIRLHPKPLHHDEKILIPILAHKNPLSLSQLQSYQKHQNHQNPHSSLLTQIPTNTPDDPNPQNNPKNTIKSKILKPSLRIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIE5</accession>
    <name>A0A8T0HIE5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G078900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIE5"/>
    <dbReference type="OrthoDB" id="1936537at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098">
        <property type="entry name" value="RAPSYN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10098:SF108">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="19603" checksum="2BE3BC067D249234" modified="2022-10-12" version="1">MYTKYLEICERLDDADGQALAHNFIGCAIQEKENLKLELVKSESGKNPVPESSVAEYERALYHHKKAAEKSGIEGRFICYTNLGLLCSTLSMWAKAAKNHKKALRCATVLENPRGQCAAVGNLGFLLYKRKKYEAAKACMIRYLQICRVINFMPGIARAHFYLGDIEAQFKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJU4</accession>
    <name>A0A8T0HJU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G208700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043454">
        <property type="entry name" value="NPH3/RPT2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027356">
        <property type="entry name" value="NPH3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32370">
        <property type="entry name" value="OS12G0117600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03000">
        <property type="entry name" value="NPH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51649">
        <property type="entry name" value="NPH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="BTB" evidence="4">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="NPH3" evidence="5">
        <location>
            <begin position="311"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="538"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="541"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0571067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="594" mass="66776" checksum="8EA22B0E9517A91E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKG0</accession>
    <name>A0A8T0HKG0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G222300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="148" mass="15506" checksum="6087FEC931C5264C" modified="2022-10-12" version="1">MGLGWDGVLVPFLSVPWPLPALLCCEASITESESIPRLSVCLSFFRSSLVRPLPPSLPRRHSVSCPPHLIARQLLPLSVRSSSSVFTHASAAPSSSFRCHPSLPAVGAPSLPPSPPSPFALVLPSLCSIAMSKFGSSAPPPSSTPTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL24</accession>
    <name>A0A8T0HL24_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG018400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035890072" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6477" checksum="9324174C44B267E3" modified="2022-10-12" version="1">MISMVTFHFCLIFISIGRLSSVLVHSVGWSSTKVRTRAVLFASQGGRGREGPGHYPKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLK0</accession>
    <name>A0A8T0HLK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DHHA1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG032100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.40:FF:000003">
        <property type="entry name" value="Alanine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050058">
        <property type="entry name" value="Ala-tRNA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777:SF9">
        <property type="entry name" value="ALANINE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11777">
        <property type="entry name" value="ALANYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA1" evidence="1">
        <location>
            <begin position="95"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="21447" checksum="BA3F8FAE0B0D96AD" modified="2022-10-12" version="1">MDISQRPSIQSHPPLTPSQKSLQLTLNREVASLKNLLETAVIPAAKKLEFRARLGEFQERIRTAQKAAEGSSLQTILHGAVASADAAVAQNQPHCVLRTDDGIDTNAVMEAVTLVTEKHKDLAVMIFSVNGQKNKVLVYAGVPYSAAKRGLVVLDWLRASLAPINGKVGGGKNGLSQGQGSNAAGIDQALAVAKAFATKIFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN29</accession>
    <name>A0A8T0HN29_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG064200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34464">
        <property type="entry name" value="OS09G0376300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34464:SF3">
        <property type="entry name" value="OS09G0376300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="165" mass="18449" checksum="84477A1ECC7F19F2" modified="2022-10-12" version="1">MAIAALYGSWRRSLLSRLFVSSADTQGKPAREQGKRQTRQKQKGKVKDHAGEPTVQPRRGRRPSRKKWVEKKVDSEFDMVIVPPDGISVSGSESDDSDWSIGWFEPHSSQFTDDEEDTFAVLMPCYGSPAPPDAVSRKTFSLNDDHKSPLLDHHGAPSLLTSQNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNM9</accession>
    <name>A0A8T0HNM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG090000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004159">
        <property type="entry name" value="Put_SAM_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108:SF1144">
        <property type="entry name" value="METHYLTRANSFERASE PMT10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03141">
        <property type="entry name" value="Methyltransf_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770902" description="Methyltransferase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0572375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="644" mass="72470" checksum="AF2F1C610E57E0A9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPH3</accession>
    <name>A0A8T0HPH3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG118100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="12579" checksum="2694F0DE0118B9A0" modified="2022-10-12" version="1">MKIPAAVDTIYRHDADTAAHLTLLSPSGHPLDQASSRCWALVVWRSRPFSAPSQADAFDPADQVPPHLAAPGPSSALLYQPNPPSGARTNQLPPPSRRSSSTPPPARHRERISLAHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQU0</accession>
    <name>A0A8T0HQU0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG167700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="6">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0573312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="18093" checksum="CCCCCD8C6E4B5CB7" modified="2022-10-12" version="1">MAIEGWQPQEDGLQEICKLLEQYRLPIVDQSCIWQKHQRCSQLPDFNNYLAFILCRAEGDVVNIRQAARLLLKNNFKSSYHLIQPAHLQYMKAEVVPCLGSLDFGIRTTVGTIISKDLPKILDSEVPGFADRPIAIFILRLLQALFINMGTYLQGFFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HST3</accession>
    <name>A0A8T0HST3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG227000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HST3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="12482" checksum="CDC4030EF9AAC36B" modified="2022-10-12" version="1">MSGLVKWRNKVRARPVGFSTHTDSIFSSVMISPSTNQISSQLSQLLFVTMVSNSASASASSHRASTSSALESSSYLPNAEVVRKCLLTALASSYSLKAFCTRSSCIFIFATCTSNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSV5</accession>
    <name>A0A8T0HSV5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG228400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044810">
        <property type="entry name" value="WRKY_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31282">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR 21-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="7">
        <location>
            <begin position="330"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="418"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="505"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="291"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="430"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0574024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="564" mass="61817" checksum="A66AFC47EF4FA532" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT05</accession>
    <name>A0A8T0HT05_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG196800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="14351" checksum="B677D56E11A0FECD" modified="2022-10-12" version="1">MKTNKHIVRMNSYARCLQLPPVVIPITKENQEQEFAQNEIYPSNLIQTKQISVTDQQRSVTTSRYHTAEVTEPSITLVTLENNQLNVVFHSALKIKKQVDRQLHRCVTHSNTVNTPEEETKQPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU32</accession>
    <name>A0A8T0HU32_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG256600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10775" checksum="FF69F30117A77CAF" modified="2022-10-12" version="1">MPRIDIFVLVADTKVESSRRRSFVRFTHLSKKGATSLRRFGHEGISPPVSLQDLITFYYRDISHRRWRRGHDAHSSVLLYSHCLLTGLRLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUC9</accession>
    <name>A0A8T0HUC9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG236800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="15772" checksum="6D13C2A64CE0D7E1" modified="2022-10-12" version="1">MQILKPPPTAGSPTHSRSSSFDDPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTSILYLNPLPQSSTASQQPARSQGMKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUW1</accession>
    <name>A0A8T0HUW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Gfo/Idh/MocA-like oxidoreductase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG274200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gfo/Idh/MocA-like oxidoreductase N-terminal" evidence="2">
        <location>
            <begin position="69"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0574587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="209" mass="22556" checksum="79A525BF75FE6D1A" modified="2022-10-12" version="1">MARQSVRFAISTPQSSPDYRPHRNSSGPPPSPFAYCGHSQLGSVFIDPAFEIGGSIVVEEMADSVPGLALLGSGVFASSQYIPKLGELVDLISLKVIWSRSEDAAKKALQLVNSYAPNAEAKWGQEGLDSVLQDKAIHAVAVVLPAQYQLEIVLRILEAGKHVIQEKPVGSCVADVRKAWSAYQALASNNSKLPIWAVAENYRFEPALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV81</accession>
    <name>A0A8T0HV81_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG302300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="6790" checksum="ACBFBD5DBE524D1E" modified="2022-10-12" version="1">MVSGHLCHVNQSGDQCILGYSGKISIPLGRGGGGTFPAREETCDVRCDAVKTAVSLAARVDVVQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVI2</accession>
    <name>A0A8T0HVI2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG284600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVI2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035796005" evidence="1">
        <location>
            <begin position="21"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7138" checksum="FF04A6873A77989A" modified="2022-10-12" version="1">MGIFQQFLLLAYVIFPTGFGGHHSVSITCQSNCPSIFNLVSSLEDLLIVHRASYIWFCKVFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW64</accession>
    <name>A0A8T0HW64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG285500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="9625" checksum="C652D41CA40751B0" modified="2022-10-12" version="1">MARSTIKCMCCEGGTYMYTQGKMGASFMFQTWRRGFICLLVLASSPFLAPIIVVSMMVGGLFLGLLLCGVAAYCALIRPSLSLVVSKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXK1</accession>
    <name>A0A8T0HXK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G035500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007789">
        <property type="entry name" value="DUF688"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371:SF26">
        <property type="entry name" value="DUF4005 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371">
        <property type="entry name" value="OS01G0551000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05097">
        <property type="entry name" value="DUF688"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="304"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="437"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="675"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="841"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="882"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="364"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="446"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="711"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="732"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="758"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="797"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="917"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1110" mass="121033" checksum="B71B7D8E297C13FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYQ0</accession>
    <name>A0A8T0HYQ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G028400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RLP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000275">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000111">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000719">
        <property type="entry name" value="MDIS1-interacting receptor like kinase 2 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052:SF29">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48052">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="786"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="13">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0575755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="841" mass="91439" checksum="F9115D150E4F14A6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I138</accession>
    <name>A0A8T0I138_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kinesin light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G109700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I138"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47689">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47689:SF2">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="36140" checksum="7949284F2FC33802" modified="2022-10-12" version="1">MFHLAEVLRLQGKLEDAEHLILDSLRILEEGGVGHSQQAVRRMSRLAEILVHTGKLQEAENIQRKILHILEMLQGPESLSTITAADNLATTLQALRKLDEAEELFLRCLRVRQRALSSTHIQIGSTLFKLAVVTTQQADEMVAEKSGNIEDIRAVYESAEDMLRRAIRIAEQRWEEALGGVAAADQAATAMLGNEASLGAKALNTLIPPFLALVRALNALSVVVMHLADLADSPAAVKEGTREAERVLRHCLTLLDKPPGVAQELVEVPELQREHVSCLHHLAALLVRNKDKGSTENSKVAEEQAERLLSRAEGIEASVATRRRSSLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2I4</accession>
    <name>A0A8T0I2I4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="8">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G114800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Extracellular space</location>
            <location evidence="8">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="8"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2I4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02176">
        <property type="entry name" value="GH16_XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000025">
        <property type="entry name" value="Xyloglucan endotransglucosylase/hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008263">
        <property type="entry name" value="GH16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01034">
        <property type="entry name" value="GH16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0052">Apoplast</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="10">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="7">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0576873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="323" mass="36799" checksum="CC92C1A764C3ADBC" modified="2022-10-12" version="1">MTIQETFQQLQKPSRKRKLAFCIILACVIFIIILAVVISTATKHEKPSNGGFSEDFSITWAENHTRISDHGKRLELILDKKSGSGFKSKEKFLFGSIKMDIKLVPADSAGTVTAYYLSSETPNHDELDFEFLGNTSGQPYILQTNVFANGTGQREQRINLWFDPTTDYHTYGVLWNRRQIVFLVDDLPIRVFTNNENMGMAFPNQQPMNIFSSIWFNGDSWATQGGRVKTDWTHAPFIATYQNYNLDACVAKDAYAPCAMPVANKWWDQSEYQALSAAQQDKVRWVEENYMVYNYCSDMKRNPTVPFECIRNSGGFLGLGSLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3D7</accession>
    <name>A0A8T0I3D7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G135200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3D7"/>
    <dbReference type="OrthoDB" id="539213at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09487">
        <property type="entry name" value="SAM_superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.50">
        <property type="entry name" value="Transcription Factor, Ets-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001660">
        <property type="entry name" value="SAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013761">
        <property type="entry name" value="SAM/pointed_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627:SF69">
        <property type="entry name" value="PROTEIN BICAUDAL C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10627">
        <property type="entry name" value="SCP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07647">
        <property type="entry name" value="SAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00454">
        <property type="entry name" value="SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47769">
        <property type="entry name" value="SAM/Pointed domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50105">
        <property type="entry name" value="SAM_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SAM" evidence="3">
        <location>
            <begin position="302"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="104"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="256"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="116"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="127"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="363" mass="39235" checksum="C11566DC5AC62D04" modified="2022-10-12" version="1">MEGEQQQQQAKRRRRPSVRLGEIGFAVPFEASSLWIEAPRQRRKSAPADVLTTGKKAPRIRPLEQLGRAEEEEWAVIEPTNGSPVKGKSSRRVFNRKVNTKLRGKARLGWTSTSTLKDEDVARDLAEGGEEEDENESEEKEILPLQGDDEAPIVSTSSESEELLGSDLKGEEEENLPAEDSGNAGSDGSEEGEPGVKPSSHGDEMQGAIEDGPGGVNGKVFSRGKQQLGERRSGRQAAIRAIRDMGREIASRDAAIVSRDAASRDTAGEPSGRFQSPAAVGNGANTVVTPNSSQRGGLAGGVSGWLQELGLGRYLELFELNEVDTEVLPHLTFEDLREMGVDAVGARRKMFNGIQELGQIRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3S3</accession>
    <name>A0A8T0I3S3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G171300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3S3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="184"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="197" mass="21698" checksum="8328E5BB5D08193C" modified="2022-10-12" version="1">MSSNYMSELFYGKPEPVWVINNRRRNMGMGGGMGGGMGGDPYYQGMSSGSYGGQGYGYNSRGTSLVPDMTVRTPLQGMSDVARIKQVLSVEGVYNVVCDIPQQSVTVSSNLSPRMVVGLIRQAMGSANIINYVDPLQPTFEQPGERQRYSSYDDSYSYAGRTGYEPSYSAPYNGRSYDNEFRPSSYSGRSNYGSSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4P5</accession>
    <name>A0A8T0I4P5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G024800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4P5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14125">
        <property type="entry name" value="STKc_CK1_delta_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000134">
        <property type="entry name" value="Casein kinase I isoform delta-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000538">
        <property type="entry name" value="Putative Casein kinase I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="9"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="303"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="417"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0578462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="479" mass="53074" checksum="00E2A577EB2849A4" modified="2022-10-12" version="1">MEPRVGNKYRLGRKIGSGSFGEIYLGTNIQTNEEVGIKLESIKTKHPQLLYESKLYRILQGGTGIPNIRWYGIEGDYNVLVLDLLGPSLEDLFNFCSRKFSLKTVLMLADQLINRVEYVHSKSFLHRDIKPDNFLMGLGRRANQVYIIDFGLAKKYRDPSTHQHIPYREHKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFLRGSLPWQGLKAGTKKQKYEKISEKKMSTPIEVLCKAYPSEFASYFHYCRSLRFDDKPDYAYLKRIFRDLFIREGFQFDYVFDWTILKYQQSQIAGAPSRPVAGPGGSSGAVAAAGTGAERLTRDTQRTADPADAARRRLVGGTGSGGIDAPKHKSPGADEGTAKETAVGGLAEPERMHASSFVRGGSSSRRAVLSSSRPAGSSEAVDGSRSLTSKIGPTSLRTSGGMQRSSPVASTDPKRTVSNRHLPPNLRNYDAALKGVESLSVEVDQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I504</accession>
    <name>A0A8T0I504_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">4-oxalomesaconate tautomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G003900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PrpF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I504"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007400">
        <property type="entry name" value="PrpF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709">
        <property type="entry name" value="ACONITATE ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43709:SF2">
        <property type="entry name" value="DUF453 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G00360)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04303">
        <property type="entry name" value="PrpF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="413"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0578176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="51884" checksum="40D858B0416AB7A1" modified="2022-10-12" version="1">MVQRMIPCLLMRGGTSRGTYFLKEHLPRDRETLDKVLLQVMGSPDPHQIDGLGGATATTSKVAVLSRSQEPGIDIDFLFAQVSVTTAMVDWGPTCGNILAGVGPAAIEMGLIPNIGNAETKVRIRLVNTGGFVEAVVQTPGKHVTYEGDVAIDGVPGTSAPIELSFVDVVGSKTGKLLPTGRLRDLIDAIEVTCIDCAVPTVVARASALGKTGYESKLELDLDVDFFRRVEGVRRIAGQMMGLGDVAGRVIPKFAMVAEPRGHGNLTARYFVPTTTHPSMAVTGGIAISCCSILEGTVAHEVSTPSLVVEQYVTHNIIVEHPSGEIPIVLKARLIPAQPDSTCSSSSSSSSSSSTDHEPELAILDVYSAGAIRTARLLFAGMVPLPSKLGLDTFTQPHEHEFRHMSEQFSQLYRSPRRKLPSKLRGKSLPSSPRALHPTSLRALNFASPRASEMPTVSRVHAMAVPAVRCPPVGVSTMCRSPRGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I524</accession>
    <name>A0A8T0I524_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G004900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I524"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="230" mass="26135" checksum="CBCF613FD636761E" modified="2022-10-12" version="1">MLSVRLMTFSGHWIKIYSAHFCILRAPSFNDYKRKSARTLQRAQICSRISSGTNPFTYTTIQGPLQLLIIIHAVRKASTTLNYTLSNTKICLRSSMRLLPDCRGSRNMPVQLKLLNHCRRRRHPTAPEDRILYQNIILIKPRLRRPTPTAPVRRSYPAPPTKGQDTVSIKKPVSPAHVQISRSTNRLNFSHHVYKRTHTPVLSVATLAKPNISGAYLQLRQAKKAAPSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I588</accession>
    <name>A0A8T0I588_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">(S)-2-hydroxy-acid oxidase</fullName>
            <ecNumber evidence="3">1.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G002300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I588"/>
    <dbReference type="OrthoDB" id="25826at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003973">
        <property type="term" value="F:(S)-2-hydroxy-acid oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050665">
        <property type="term" value="P:hydrogen peroxide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000204">
        <property type="entry name" value="Peroxisomal (S)-2-hydroxy-acid oxidase GLO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578:SF141">
        <property type="entry name" value="(S)-2-HYDROXY-ACID OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10578">
        <property type="entry name" value="S -2-HYDROXY-ACID OXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="79"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="292"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="315"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0578155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="41272" checksum="E33FA6F812C9121E" modified="2022-10-12" version="1">MSTEIVNVDEYEALAQRRMPKMAFDFFSSGSEDQVTLRENRAAFTRIRLRPRILVDVSNIDVTTSVLGFKIAMPIMVAPTALHKMAHPDGELATVRAVSAANTIMILSASATCSMEEIAATGPGLRLFQLYVYKDRNITRTLVRRAEQAGFKAIVLTVDTPRLGRREADIKNRFKIPSHLSYKNMEGLMNVNKEIDKMNKTSGSEAAAWVDNHFDRSLNWKDVKWLQSITKLPVLVKGILTAEDAVLALQAGVAGIMVSNHGARQLDHVPATISVLEEIVKAVAGRVPVFLDGGVRRGTDVFKALALGASGVFIGRPIPYALSVDGEAGVTKVLQMLRDEFELTMALMGVCSVKEIRRQHVQTEQDSVKLLLSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I595</accession>
    <name>A0A8T0I595_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G049600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I595"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17658">
        <property type="entry name" value="PTPc_plant_PTP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000045">
        <property type="entry name" value="Tyrosine-protein phosphatase non-receptor type 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050348">
        <property type="entry name" value="Protein-Tyr_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134">
        <property type="entry name" value="RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19134:SF449">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00102">
        <property type="entry name" value="Y_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00194">
        <property type="entry name" value="PTPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50055">
        <property type="entry name" value="TYR_PHOSPHATASE_PTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="8">
        <location>
            <begin position="78"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="9">
        <location>
            <begin position="263"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="357" mass="40271" checksum="B16B7C9E3DC5F49A" modified="2022-10-12" version="1">MSSSPVTPTPSTTSRMRGGVRASDREYDLGVVAKQQQIARDLPLPSLTASQLLACENALKQLKLKAKGNGGRNLDGAIDCEFDTLQVERMHNYKAFSQTTVALAPFNKAKNRYVNVLPYDSTRVVIARKHSGPPLSDYINASFVQDNVHEYLPRYIATQGPLPTTVNDFWTMVLQQRCPVIIMLTRIVDGSQNKCAHYFPKDENQSQTYGQILVINKSFICSPHGIARRIFTVQDTKSPEQPWTVVHYEYLEWPDHYVPPSTRSVRELIRASFGIPPQAGPFVVHCSAGIGRTGTYCAIDHTLRRILQGDLGAVDIENTVRQFRLQRDGMVQTTDQYRFCYEAVIQELEDYINTAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5S1</accession>
    <name>A0A8T0I5S1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G016800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000046">
        <property type="entry name" value="Fasciclin-like arabinogalactan family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052806">
        <property type="entry name" value="Fasciclin-like_AGP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33985:SF29">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33985">
        <property type="entry name" value="OS02G0491300 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="86"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="232"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="232"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="29240" checksum="EB50C2E063C8BBD9" modified="2022-10-12" version="1">MRAPEQHPQAQKLLQERTLQYTMAASPISLRGHAAPWAALCCALLFSAAVLAEAAPTLAAAIIAPAPAPLLGVPAPAPAPKVLTLHEKVVAALRAAGHYGAISGLLDSLGDSTIIKPGITLFAPDDGAFDGLNMNSSLLLTTTLDYHVSTTVYTYQQLSTLPLNSTIQTAAPNVEIIVTSTGTNGFRLDDVAISDPDLYSDGQVAVQGVSSVFNTAKYNKGVVPPEAAPAPLAGEAPGAAPPGYITTPTGPKPAGSNSTKSDAARVVTTILGTMILASSVSVAVSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6N4</accession>
    <name>A0A8T0I6N4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G045400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6N4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9134" checksum="8EB6B435EAAC5D80" modified="2022-10-12" version="1">MVSSFMDPLPKTGSMIPDPFLFRNMCRESGGIQCGSCACRLASGWSPNDPRLHDSTSTAEVTAACAKRSVRRTCFGLQLVWEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8B9</accession>
    <name>A0A8T0I8B9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G045600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8B9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10831" checksum="F46FB71F3E1D2BB7" modified="2022-10-12" version="1">MSMVHGFSKRRALVSQAAEAVPERAPSGSFKTVLQAFVTSGAMGKPPGSHASNGSSEGYTLLSEEIERADFERKLMEGKDKPAILNVDIEIRWLPNGLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8N2</accession>
    <name>A0A8T0I8N2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MLO-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">MLO</name>
        <name evidence="11" type="ORF">KC19_4G069700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in modulation of pathogen defense and leaf cell death.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminus contains a calmodulin-binding domain, which binds calmodulin in a calcium-dependent fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the MLO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8N2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004326">
        <property type="entry name" value="Mlo"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31942">
        <property type="entry name" value="MLO-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31942:SF77">
        <property type="entry name" value="MLO-LIKE PROTEIN 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03094">
        <property type="entry name" value="Mlo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="6 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 8" id="KW-0568">Pathogenesis-related protein</keyword>
    <keyword evidence="4 8" id="KW-0611">Plant defense</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="553"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="553"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU280816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0579061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="603" mass="69443" checksum="57857CCB8B6FF278" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEB6</accession>
    <name>A0A8T0IEB6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G033800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="29171" checksum="81178C8C1B69B4EC" modified="2022-10-12" version="1">MYNLVGEQDATASCSGVVNMSRCEACTGVVNMSRCEACSGIVNMSRCETMTDAELDSDNWKAAQTNCIMTDYSDEDESMEPDCSCSSDTSYESDDSPRRRRTQIRKRKSKAKKSPRRGRPKGRPARKREESDSTSSSDSSGSPPRQGVYWEKRLQNSRTPPRRKIHTYASMNCQRNYIPVSKRLEQYNRSRSANGVSIGRRAQRAVDGTYNVEFWGSDDDDFPPTLWQRSLYKGRYFTPAESSYGAFMDRGNLPQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGZ8</accession>
    <name>A0A8T0IGZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G040300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035769625" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9592" checksum="A261AA84783B20F7" modified="2022-10-12" version="1">MLFLLFLLLLLRPLLVRVIGAGDVEWSRVERRLELGFGVWRSGGEIWRLLEVVVMLMWRLVVRVVEGESGGCNAVAEVIGGIVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHX4</accession>
    <name>A0A8T0IHX4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G094600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the major facilitator superfamily. Sodium/anion cotransporter (TC 2.A.1.14) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHX4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042170">
        <property type="term" value="C:plastid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd17380">
        <property type="entry name" value="MFS_SLC17A9_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000058">
        <property type="entry name" value="ascorbate transporter, chloroplastic isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1250.20:FF:000086">
        <property type="entry name" value="ascorbate transporter, chloroplastic isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050382">
        <property type="entry name" value="MFS_Na/Anion_cotransporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044777">
        <property type="entry name" value="SLC17A9-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662:SF446">
        <property type="entry name" value="SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11662">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="584"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="12">
        <location>
            <begin position="236"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="166"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0582902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="643" mass="70828" checksum="A3C445856E540402" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II01</accession>
    <name>A0A8T0II01_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Adaptor protein ClpS core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G059700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II01"/>
    <dbReference type="OrthoDB" id="2015242at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022935">
        <property type="entry name" value="ClpS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_bL12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33473:SF13">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE ADAPTER PROTEIN CLPS2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="ClpS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Adaptor protein ClpS core" evidence="2">
        <location>
            <begin position="111"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="19689" checksum="00E01FCABF42B4A0" modified="2022-10-12" version="1">MAVAMGSVAQVWSVASTLQSSTGGAGESRVPFGASGGLDVGGCVRAGAGTQKATSVGSVGVVRAALGGSRGGSSVLERPKLDQSGSDTAPQTEEGGESGKDRQRVRTGGGDRYRVLLLDAEHHTESYVEKTLPKAVPGVTPEQARKCCLEARLFGKSVVMVAVKEHAEMHTYSMARFRLRATIEPDSTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIV8</accession>
    <name>A0A8T0IIV8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G090700</name>
        <name evidence="7" type="ORF">KC19_3G090800</name>
        <name evidence="8" type="ORF">KC19_3G090900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIV8"/>
    <dbReference type="OrthoDB" id="5600418at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="8"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0582847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12631" checksum="8A486045E76A4CCC" modified="2022-10-12" version="1">MDGGMDNCCICCDVVKNRVEVDACRHTFCRTCLLNWLQFERKKYNRMSCPVCRTKIQKFRRVKEIIWEHSTNFRKPDVRNPGTFAYRRARQLPVTASNICKQRLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKR2</accession>
    <name>A0A8T0IKR2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G103600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="18"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0583033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1152" mass="129094" checksum="32014F63B9030A86" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPA3</accession>
    <name>A0A8T0IPA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">STI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G238000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPA3"/>
    <dbReference type="OrthoDB" id="2423701at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051879">
        <property type="term" value="F:Hsp90 protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000102">
        <property type="entry name" value="hsp70-Hsp90 organizing protein 3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000004">
        <property type="entry name" value="Putative stress-induced-phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000010">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000020">
        <property type="entry name" value="Stress-induced phosphoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.260.100:FF:000002">
        <property type="entry name" value="Stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904:SF533">
        <property type="entry name" value="HSP70-HSP90 ORGANIZING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22904">
        <property type="entry name" value="TPR REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13414">
        <property type="entry name" value="TPR_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0346">Stress response</keyword>
    <keyword evidence="6 11" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="2"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="70"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="13">
        <location>
            <begin position="140"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="271"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="410"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="11">
        <location>
            <begin position="444"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="STI1" evidence="13">
        <location>
            <begin position="548"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="208"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0584837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="599" mass="66487" checksum="3DCDD228D941379D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ12</accession>
    <name>A0A8T0IQ12_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">alpha-glucosidase</fullName>
            <ecNumber evidence="3">3.2.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Maltase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G258600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal, non-reducing (1-&gt;4)-linked alpha-D-glucose residues with release of alpha-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.20"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.20" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090599">
        <property type="term" value="F:alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06602">
        <property type="entry name" value="GH31_MGAM_SI_GAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14752">
        <property type="entry name" value="GH31_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1180:FF:000044">
        <property type="entry name" value="Alpha-glucosidase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1760">
        <property type="entry name" value="glycosyl hydrolase (family 31)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030459">
        <property type="entry name" value="Glyco_hydro_31_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF133">
        <property type="entry name" value="P-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00707">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035901656" description="alpha-glucosidase" evidence="10">
        <location>
            <begin position="25"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 N-terminal" evidence="12">
        <location>
            <begin position="140"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="11">
        <location>
            <begin position="301"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="13">
        <location>
            <begin position="681"/>
            <end position="771"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00041343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0585105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="930" mass="103657" checksum="D8CD7D9201611C4D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ41</accession>
    <name>A0A8T0IQ41_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G263500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ41"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051257">
        <property type="entry name" value="Diverse_CBS-Domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN CBSX3, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43080:SF29">
        <property type="entry name" value="OS02G0818000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="213"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="269" mass="28691" checksum="E6F684E2BFD1A29B" modified="2022-10-12" version="1">MRVAVLQHNTNIRFRTRIASTGVGAPSPLHAYPIASNTSAMATAVSSIALSGPAALDCASRGSNRFSWSSSSAVVMPVKGLQRVGLRARGVLGCVRAGERVDVDVKEAGAKGDVLPSGEWAENFSMLNYEDLSKYYEDVLFKPEAQPSTHLADVMSKTIVTASPEQALEEIDHYFANISGVPVVDAEHRCVGVLSKKDRAKASDLKAKVKDVMSSPAITLSANKIVSDAAILMLKNKIHRIPIVNESNQVVGIVTRTDIFSALEGGSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISX6</accession>
    <name>A0A8T0ISX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G037200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12971" checksum="C48AE980DB2D39C2" modified="2022-10-12" version="1">MPFYYFELSLCKFVSCELSTVGCHITLGRRHFDGTTRLLFRRSEFVFHTDHPTFISRSQSGKTERFFYNDNVILLSSLQLPYSEVGPDVEGGSIHVLEDNCLIEVQLPLVPSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITM2</accession>
    <name>A0A8T0ITM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G139200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035755654" evidence="1">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6649" checksum="A127ED30D31C21C9" modified="2022-10-12" version="1">MTFLSTMLLFVLFSCSSETRTCSPWMLLSRSTTSDQGGSPIALRTAYTLVSKFEDAGASFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU77</accession>
    <name>A0A8T0IU77_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G073900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000037">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044178">
        <property type="entry name" value="CYP28-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47875:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP28, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="1">
        <location>
            <begin position="141"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="351" mass="37425" checksum="1C320E035597967C" modified="2022-10-12" version="1">MAGAWCTTCCSPSVLPAVAICKRVVKSSSSSACLSSALRRQSFLGAQSSSRRSEVVRCCCASTSRSESSCSDSGSHFVTRRQALLLVSGAAAVVVASPSYADEEISSSAVDTTITDRVYLDLMECPSLARSDRTLGNTSLICSDGEDLGRIVIGLYGKQVPQTVKNFKAMCTGAAGSSYEGTIFNRVLQGQYIQAGRQGPRDKGETSPPTKLDRNEEVVRGNSFKLRHQRPGTVSLCLSENDDEEAIKLNTDYRNVEFMITTGPGPASQLDNGNIVFGTVLEGMEVVAAISTVPTYKPSGRIQQFNSFAQLLGDDRAASARANWDKPLKSVVIKRCGVLNVARPGLATSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUH2</accession>
    <name>A0A8T0IUH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyl-D-glucosamine kinase</fullName>
            <ecNumber evidence="2">2.7.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GlcNAc kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G085500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic-type N-acetylglucosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.59" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045127">
        <property type="term" value="F:N-acetylglucosamine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002731">
        <property type="entry name" value="ATPase_BadF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052519">
        <property type="entry name" value="Euk-type_GlcNAc_Kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43190:SF3">
        <property type="entry name" value="N-ACETYL-D-GLUCOSAMINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01869">
        <property type="entry name" value="BcrAD_BadFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase BadF/BadG/BcrA/BcrD type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0586371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19512" checksum="46326EA64A309B9D" modified="2022-10-12" version="1">MRAEDGRGPKTSLTGAILKKLNLSTSEDLIGWVYEDTSWARVSALVPVVKACAQDNDIVAIELLEGAVSELANSVQAVVRTLNLHGRDGRKAFPFVMVGGVLDYENGWDIRKPLIKKVLELFPGAQPTVPKLEPALGSAMLAWSRYSDRLTKDAQQSIERGALQVVNGVLSRENTSLPTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVW1</accession>
    <name>A0A8T0IVW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">diaminopimelate epimerase</fullName>
            <ecNumber evidence="3">5.1.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G140100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S,6S)-2,6-diaminopimelate = meso-2,6-diaminopimelate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.310.10:FF:000009">
        <property type="entry name" value="Diaminopimelate epimerase chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.310.10">
        <property type="entry name" value="Diaminopimelate Epimerase, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689:SF0">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="DIAMINOPIMELATE EPIMERASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54506">
        <property type="entry name" value="Diaminopimelate epimerase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0587089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="377" mass="40815" checksum="B6E1459351EC2F08" modified="2022-10-12" version="1">MALRNHLLLGNRAGAAAFGGECAAFLPGKPLGTRAQRLAVRRSVLLWGARANLDSATDLFTDAATGRAGGGSVKLENRLEKVFDVVKGKESKRTLEFVKYHGIGNDFIMVNNLDSPVPIITPAEAVRLCDRHTGIGGDGVIFVMRDNENYQMRIYNSDGTEPEMCGNGIRCVAKYLAELEKATAPQSYKVLTLAGYMILELREDGQVCVDMGPPYLEAAEIPTKLAAKGEVVKAPLVVDGKTWSVTCVSMGNPHCITFGEEGGEGLNVDAIPLEQIGPLFEHHEMFPARTNTEFVEVISRTHLKMRVWERGAGATQACGTGACALVVAAVKEGRAERNCTVDLPGGPLEIEWRESDNHIYMTGPAERVFQGSVVLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZI8</accession>
    <name>A0A8T0IZI8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G220000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF46">
        <property type="entry name" value="LEUCINE RICH REPEAT-CONTAINING DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="25"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="3">
        <location>
            <begin position="300"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance protein Roq1-like winged-helix" evidence="5">
        <location>
            <begin position="582"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0588148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1495" mass="161815" checksum="40D7FF53FAF56BE3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZT9</accession>
    <name>A0A8T0IZT9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">long-chain-alcohol oxidase</fullName>
            <ecNumber evidence="5">1.1.3.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_2G246700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a long-chain primary fatty alcohol + O2 = a long-chain fatty aldehyde + H2O2</text>
            <dbReference type="Rhea" id="RHEA:22756"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17176"/>
            <dbReference type="ChEBI" id="CHEBI:77396"/>
            <dbReference type="EC" id="1.1.3.20"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GMC oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.20" evidence="5"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046577">
        <property type="term" value="F:long-chain-alcohol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000172">
        <property type="entry name" value="GMC_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007867">
        <property type="entry name" value="GMC_OxRtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012400">
        <property type="entry name" value="Long_Oxdase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46056:SF12">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05199">
        <property type="entry name" value="GMC_oxred_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00732">
        <property type="entry name" value="GMC_oxred_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028937">
        <property type="entry name" value="Lg_Ch_AO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase N-terminal" evidence="15">
        <location>
            <begin position="348"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-methanol-choline oxidoreductase C-terminal" evidence="16">
        <location>
            <begin position="651"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="736"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR028937-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR028937-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0588492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="804" mass="87145" checksum="38CD0085A5635C1E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J020</accession>
    <name>A0A8T0J020_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">U6 snRNA phosphodiesterase</fullName>
            <ecNumber evidence="5">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G012200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 2H phosphoesterase superfamily. USB1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J020"/>
    <dbReference type="OrthoDB" id="49151at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990838">
        <property type="term" value="F:poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034477">
        <property type="term" value="P:U6 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1140.10:FF:000008">
        <property type="entry name" value="U6 snRNA phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03040">
        <property type="entry name" value="USB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027521">
        <property type="entry name" value="Usb1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13522:SF3">
        <property type="entry name" value="U6 SNRNA PHOSPHODIESTERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09749">
        <property type="entry name" value="HVSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="5">
        <location>
            <position position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0589314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="32362" checksum="6957F1328FEDBF3D" modified="2022-10-12" version="1">MDALQCYGSSSDSDIEDEIDEAALRAKRFKSASDSTTERSSGSSLSLPPPPPELFSSVPDAVTKKWSASEHGGRVRSFPHVEGNYSLHVYIPVVLSSSIQTKLSPYLQKAVSLFPALKSMADDDLSANVNSKQGIKLATEFHVSLGRTVPIRIHQVDTMVHMLRRKFEGQKRFWIEFGSWDVFVNDDRTRSFLSLEVVATGYSEIKRQVSLVDDVYRLHSLPTFYQNPRPHISLTWALGDVVDALATVARELNAMVRLREEKNCIWTAPATKIECKIGQKLHPIWTATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1U4</accession>
    <name>A0A8T0J1U4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G002700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1U4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="47" mass="5163" checksum="9B2F3159C66C14E3" modified="2022-10-12" version="1">MQMLDVNLEDEAEEDGANVDLDSQRKGKCVVLKTSTQQVSGLHVAIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J266</accession>
    <name>A0A8T0J266_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G064200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J266"/>
    <dbReference type="OrthoDB" id="2020015at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022227">
        <property type="entry name" value="DUF3754"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645">
        <property type="entry name" value="AMINOPEPTIDASE (DUF3754)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33645:SF11">
        <property type="entry name" value="AMINOPEPTIDASE (DUF3754)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12576">
        <property type="entry name" value="DUF3754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="498" mass="57406" checksum="AEB6F4FA5026560F" modified="2022-10-12" version="1">MAQPRKDILEIDRESVIVISKSKLIDGLTNLIGPDERSEFKILCRRVESTIRAWYNLQFEDLNQLYSLFDPVHGRRKLDQLQPSPAKVDNMEQRFLKILFQVMEKSNFQILNDAEVELAQAGQYLVNMPIAVDKTKLDKKLLTTFFKENKVDEVPSYADQYIIFRRGIGIDKTTDYFIMPKLDLLIERTWNWTLQKLGLQKPPNQQPAHVHSLSRKRSQVQTLMEDSAQNEKNDSGADANELRFERIRIQNMDISFNNLFTQNTVQEPTFDRMIVVYRRASKPHHILDPLGDRSIHIRHFRNIPLADMELVLPEKKNPGLTPMDWVKLSISAVLGLVALFGSTESGKGDVWVLIAILGGIIGYIAKIYFTFQANLVLYQNLITQSLYDKQLDSGRGTLLHLCDDVIQQEVKEVIMAYFVLMSQGKATDQELDRRCEQLMSEKFGEKCDFDVEDALVKLEKLEIVTKDANGKYSHQPLRKANEAIGETTDELVERRSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2R5</accession>
    <name>A0A8T0J2R5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G081800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="306" mass="33941" checksum="7D412826BCDE17D6" modified="2022-10-12" version="1">MGPKVRPEKRARKEDGVGHGDPIREDGCIGNYIQRIGVALRKDTGKYVVEMRPPYWKLKLNFGSYNLQVEAMIARDYGAFLRASTAEENSASAGGFGADDKLYQFEESPGIFEGIGGTMDRRQRIRPLYKELIKEKWSGEGNPPHHQFCKDARKDIDIAIGVFRERFPERFSPPTETEKGVAKVEPVDGGIHCASSSSNPKVRVPPEPALGPVGREDGAIAGGVVSPWADLQISVAMNGSPSRILLDMKVPPIDDQHIFLLLKACFDKVKDEMITRCFEKFLEELVPCPYDPLSIPAIDLSEDPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J422</accession>
    <name>A0A8T0J422_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">phosphopyruvate hydratase</fullName>
            <ecNumber evidence="3">4.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G025600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="9">Mg(2+) is required for catalysis and for stabilizing the dimer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J422"/>
    <dbReference type="OrthoDB" id="1739814at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.390.10:FF:000001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.120:FF:000002">
        <property type="entry name" value="Enolase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="entry name" value="Enolase-like C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="entry name" value="Enolase-like, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902:SF1">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00178">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00001">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="Enolase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="Enolase N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enolase N-terminal" evidence="11">
        <location>
            <begin position="4"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase C-terminal TIM barrel" evidence="10">
        <location>
            <begin position="147"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="215"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="380"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0589513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="445" mass="48441" checksum="1FF28143BDF68384" modified="2022-10-12" version="1">MATIKSIKARSIFDSRGNPTVEADIHLSDGSWYRAAVPSGASTGVYEALELRDGGKEYMGKGVQKAVDNVNNIIGPALVGKDPTDQSAIDNFMVHELDGTQNEWGWCKQKLGANAILAVSLAVCKAGAGVKKLPLYQHIANLAGNKEIVMPVPAFNVINGGSHAGNKLAMQEFMILPTGASSFKEAMKIGTEVYHNLKAVIKKKYGQDATNVGDEGGFAPNIQDNREGLELLKTAIAKAGYTDKVVIGMDVAASEFYNEKDKLYDLNFKEDNNDGKAKLSGDEFIKLYESFVSEYPILSIEDPFDQDDWAHYSKINELMGDKVQIVGDDLLVTNPKRVAYAIEKKSCNALLLKVNQIGSVTESIEAVVMSKRAGWGVMTSHRSGETEDSFIADLAVGLSTGQIKTGAPCRSERLAKYNQLLRIEEELGDKAVYAGLKFRKPVEPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5R9</accession>
    <name>A0A8T0J5R9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBD1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G137300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5R9"/>
    <dbReference type="OrthoDB" id="2357150at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006913">
        <property type="term" value="P:nucleocytoplasmic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13179">
        <property type="entry name" value="RanBD_RanBP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.29.30:FF:000715">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000156">
        <property type="entry name" value="Ran_bind_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045255">
        <property type="entry name" value="RanBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045256">
        <property type="entry name" value="RanBP1_RanBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138:SF87">
        <property type="entry name" value="E3 SUMO-PROTEIN LIGASE RANBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23138">
        <property type="entry name" value="RAN BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00638">
        <property type="entry name" value="Ran_BP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00160">
        <property type="entry name" value="RanBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50196">
        <property type="entry name" value="RANBD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="4" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RanBD1" evidence="6">
        <location>
            <begin position="36"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="163"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="176"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="24450" checksum="01AF22EF506FF9BD" modified="2022-10-12" version="1">MAGDDEKEVRVVEEATSSEPAEGSEEVHGEEDTGAQIAPIVKLEEVAISTGEENEDVLLDMKAKLYRFDKEGTQWKERGVGQVKILEHKSTKKVRLLMRQNRTLKICANHMVTAATQLQEHAGSDKSWVWHAKDYSDGELKEELFAMRFGSVESAQKFKDVYEAAQENSSGKTEEKNEEADETADLLDKLKVESKSEETPAPEETKTEVKEATESKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6D9</accession>
    <name>A0A8T0J6D9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">isoamylase</fullName>
            <ecNumber evidence="9">3.2.1.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G156000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Hydrolysis of (1-&gt;6)-alpha-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limit dextrins.</text>
            <dbReference type="EC" id="3.2.1.68"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.68" evidence="9"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6D9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004135">
        <property type="term" value="F:amylo-alpha-1,6-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019156">
        <property type="term" value="F:isoamylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005980">
        <property type="term" value="P:glycogen catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11326">
        <property type="entry name" value="AmyAc_Glg_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02856">
        <property type="entry name" value="E_set_GDE_Isoamylase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000054">
        <property type="entry name" value="Glycogen debranching enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="GH13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044505">
        <property type="entry name" value="GlgX_Isoamylase_N_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011837">
        <property type="entry name" value="Glycogen_debranch_GlgX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048650">
        <property type="entry name" value="ISOA1-3-like_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02100">
        <property type="entry name" value="glgX_debranch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43002">
        <property type="entry name" value="GLYCOGEN DEBRANCHING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21156">
        <property type="entry name" value="ISOA1-3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 13 catalytic" evidence="10">
        <location>
            <begin position="268"/>
            <end position="686"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00066531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0591177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="796" mass="88973" checksum="1AD5B8C059CEF467" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J938</accession>
    <name>A0A8T0J938_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G174100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J938"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009627">
        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039265">
        <property type="entry name" value="DIR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122:SF13">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_LIPID-TRANSFER PROTEIN_SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122">
        <property type="entry name" value="LIPID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00234">
        <property type="entry name" value="Tryp_alpha_amyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035859379" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="11626" checksum="95921E260BA66083" modified="2022-10-12" version="1">MKLQVTAACLVVLLMASEMVITSEAAGCDIFQLVPCMAASKNARVTPSKQCCTNIGNMGKGLVGAKCLCSLLNHPLAKSNGVVPRIALAIPQKCRIAVPKGFVCQGIRVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9H4</accession>
    <name>A0A8T0J9H4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">anthranilate synthase</fullName>
            <ecNumber evidence="4">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G262500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterotetramer consisting of two non-identical subunits: a beta subunit and a large alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9H4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000027">
        <property type="entry name" value="Anthranilate synthase beta subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050472">
        <property type="entry name" value="Anth_synth/Amidotransfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418:SF4">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43418">
        <property type="entry name" value="MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00097">
        <property type="entry name" value="ANTSNTHASEII"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00099">
        <property type="entry name" value="CPSGATASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00096">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="12">
        <location>
            <begin position="96"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0592564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="32843" checksum="C302AF5D0110D16B" modified="2022-10-12" version="1">MATAALASGVCVEGTLASNLHATAGGNSCIASQLRPQPSFLGVSRASSPFLGLRVRQSRAASSRRSETCSALRVESSAVDVNEGVEEAKEERSVIVIDNYDSFTYNLVQYLGDLGCKIEVYRNDEITVDELRAKKPRGILISPGPGAPQDSGISLQVVRELGPTIPLFGVCMGLQCMGEAFGGKIVRAPNGVMHGKSSPVFHDEKGEPGLLDGLPSPFTACRYHSLVIEQETFPADQLEVTAWTEDGLVMGVRHRVYKHIQGVQFHPESIITQNGMQIVGNFLKMLDRKEAADQEGTEAKVLETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAA3</accession>
    <name>A0A8T0JAA3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G283800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="49"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="410" mass="48076" checksum="58AEBE54BF6530AC" modified="2022-10-12" version="1">MGFQSNCPYDPCTKRSTPNVSSRSTDVFDKSEALDRERLEVACLRQDIIDEYEKKSAELLKYLDSMESAFDHQRSEYEDRETNLRRENEELKHELAHGCRAHVAELLVKEQDREEKAQQVVQALQLLKSEMKEKERIAQKEHKKAKELQDMVEDLQLTLEKKEEEHEIVRRREERTRKHVEDENDELRRKAALGWMLGCLSELYLRLDPEIGTGGIMKLVRKVQRELECGNQVFSTGGMMPPKLEYELIQREIRRLINASATIRPDLTEKLRTSASMLRTTKPKEFTGELPGDRRKKLRVNKCLRDQEAALRSISAPSQLPSRREAASFQPFILRDHPKQKHHIACHQDVQKRSSGNWEEVRLLEADQATKVAKQTSYQEIKKILQGLESSMTYLLGQERRRRLYNQRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAC0</accession>
    <name>A0A8T0JAC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_1G210300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000177">
        <property type="entry name" value="Cysteine-rich receptor-like protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035845794" description="Protein kinase domain-containing protein" evidence="15">
        <location>
            <begin position="30"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="635"/>
            <end position="913"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0591899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="968" mass="108197" checksum="F280A502DD3EDE03" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBR2</accession>
    <name>A0A8T0JBR2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cation efflux protein cytoplasmic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G277800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.1350:FF:000005">
        <property type="entry name" value="Metal tolerance protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1510.10:FF:000005">
        <property type="entry name" value="Putative Cation diffusion facilitator 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="entry name" value="Cation efflux protein transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="entry name" value="Cation efflux protein, cytoplasmic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058533">
        <property type="entry name" value="Cation_efflux_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050291">
        <property type="entry name" value="CDF_Transporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840:SF13">
        <property type="entry name" value="CATION EFFLUX PROTEIN CYTOPLASMIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43840">
        <property type="entry name" value="MITOCHONDRIAL METAL TRANSPORTER 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="Cation efflux protein cytoplasmic domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="Cation efflux protein transmembrane domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein transmembrane" evidence="8">
        <location>
            <begin position="123"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="Cation efflux protein cytoplasmic" evidence="9">
        <location>
            <begin position="328"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0592746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="409" mass="45996" checksum="A87CA842B71FA5CA" modified="2022-10-12" version="1">MSGSSEMEENGVHEPLLQSNESIETDRGEKANGSVRSRNFDADEATLPVVSENSSKWKYKYHCVLSGDEFCESHNHSEGQREYNRKQREMLARFHEIDSMTARNTGSGDQEEPRESFAINFSYCTNLFLFIIKVIAAARSGSLAIVASALDSLLDLLAGAILWFTKWSMQHINKYKYPIGKSRVQPVGIVVFAAIMASLGLQVLLTGVQELIEGDSTYSLDNRERVWLITVMSTVILSKLGLFLYCRTFRSEIVQTYATDHKLDMLTNSVGLAAALLADWSKWWIDPAGAILLALYTISNWSKTLIENAGSLVGQSAPPEFLQLVTYVAYNHHPKIRRLDTIRAYMLGGLYFVEVDIELPEDMLLREAHNIGETLQNKLEAMPEVERAYVHLDFECSHKPEHDGGSFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDK0</accession>
    <name>A0A8T0JDK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G337100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009534">
        <property type="term" value="C:chloroplast thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010206">
        <property type="term" value="P:photosystem II repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00990">
        <property type="entry name" value="cpPDZ_AtDEGP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000001">
        <property type="entry name" value="Periplasmic serine protease DegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000103">
        <property type="entry name" value="Protease Do-like 1, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039382">
        <property type="entry name" value="DEGP1/8_PDZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF2">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="PDZ" evidence="9">
        <location>
            <begin position="401"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0593535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="53336" checksum="AE367B64976FE0B7" modified="2022-10-12" version="1">MALSLATHSAHLHLPAPHTNQFACALRNVGVSASNGARFHPLGGLLRNGKRTRFLGVNVVIHSRVRSRLELGSAVPRLMGILASSVNERKAGAGDGGGDVELRGFGEAEDGGAASVSGREEGSCVGGSLWWGLGQRVWGGGRGWSSLLAKLVSASSAAAVWVTSAAIVVVLLTSVPLDATASVAAPRRLRGDELATVQLFQENTPSVVYITNLAVRRDVFTLDVMSVPQGSGSGFIWDNKGHVVTNYHVIRGASDLRVTLGDQSVYEADVVGYDEDKDVAVLHIDAPEDKLRPLPVGSSYDLLVGQKVYAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQDVIQTDAAINPGNSGGPLLDSSGNLIGINTAIYSPSGASSGVGFSIPVDTVSGIVDQIVKFGKVTRPVLGISFAPEQSVEQLGVSGVLVLDAPPNGPAGKAGLRPTTRDSYGRLVLGDIITSVNGKKITNGSDLYKILDRCKVGDTVKLEVLRGDRKVGVDVTLEPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5H8</accession>
    <name>A0A8T0G5H8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G065700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5H8"/>
    <dbReference type="OrthoDB" id="264603at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:000813">
        <property type="entry name" value="Vesicle-associated protein 1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF6">
        <property type="entry name" value="AT11025P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019693">
        <property type="entry name" value="VAMP-associated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="MSP" evidence="9">
        <location>
            <begin position="5"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="175"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="245" mass="26947" checksum="BE431DE7D97826DE" modified="2022-10-12" version="1">MPTELLSIQPGELKFPFELKKQISSSLRLVNSTDNYVAFKVKTTSPKKYCVRPNTGIVQPHSSAEVTVTMQAQREAPPDMQCKDKFLVQSVIAPSAKEVSQEMFNKEEGRDVHEAKLKVLYVSPPQPPSPITESNEEEGNSPKASPVVDNGERHHLLADPVNQTAKTESEWKFKLNETKAALNALTEERNQAVQQSRSFQQELQAYKSGSGAGGLTDVQKAQGFSFLFVILVGLLGMLVGYLLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6A5</accession>
    <name>A0A8T0G6A5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ALOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G054700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant homeotic and developmental regulators ALOG protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6A5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009299">
        <property type="term" value="P:mRNA transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009416">
        <property type="term" value="P:response to light stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040222">
        <property type="entry name" value="ALOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006936">
        <property type="entry name" value="ALOG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31165:SF2">
        <property type="entry name" value="ALOG DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31165">
        <property type="entry name" value="PROTEIN G1-LIKE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04852">
        <property type="entry name" value="ALOG_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51697">
        <property type="entry name" value="ALOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ALOG" evidence="9">
        <location>
            <begin position="123"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0553997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="291" mass="32277" checksum="A9AAF41B18BD4EFE" modified="2022-10-12" version="1">MTSDFRNTEFRNLLNPTGAPGIHPGNYIPRPGETSFNIREDHSFNISALHRPDSKPANIRENDFASRMQSLLSGEVALANHLDHGAGPSSLVMSSPGLVPNGSVSPGMQVDAQHDQNSRAPSRYEAQKRRDWNTFGQYLRNHRPPLALARCTGVHVLEFVRYLDQFGKTKVHVQSCPFFGLPHPPHPCPCPLRQAWGSLDALIGRLRAAFEENGGKPESNPFGARQVRLYLREVREMQAKARGIAYEKKKRKRMPPNSEGASNTGLNGVNEMNMSGMSNGNVHTLPGQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6E4</accession>
    <name>A0A8T0G6E4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TMEM205-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G096700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6E4"/>
    <dbReference type="OrthoDB" id="1641132at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025423">
        <property type="entry name" value="TMEM205-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053009">
        <property type="entry name" value="Xanthocillin_Biosynth-Assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT PLANTS LEA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23241:SF102">
        <property type="entry name" value="LD23009P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13664">
        <property type="entry name" value="DUF4149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="TMEM205-like" evidence="6">
        <location>
            <begin position="48"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="23579" checksum="82582D25CB7B2555" modified="2022-10-12" version="1">MGWFTNLVVIMSCVAGGLVLYPVQIVDSGRGEQAGVTLSGVVRLVHLLSFATAFGTSLWASFIGGIIMFKNLPRHQFGNLQAKMFPAYFKLLMVCCSFCVSAMATTHPWNVATKRERLQIVSLGVSLFTVVVNLLVFQPLTVKIMKQRHKIEKDEGIGNEVGRSMNLEAAKKNPELAKINKTFGMVHGFSSLANIFCFGGLAFHSWYIASRMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G937</accession>
    <name>A0A8T0G937_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G088500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G937"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9495" checksum="3FDB7F53324D593C" modified="2022-10-12" version="1">MKDYSVPVCSFPLKTQYIPSNDALCQALERYLIVFPEAIPVIPEPVDLFALNVEPNFMSPQGRIIKETAGKHIRFQTQRTFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9X7</accession>
    <name>A0A8T0G9X7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G157800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9X7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="56"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1084" mass="124141" checksum="DE3AE5F7116214A4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBX9</accession>
    <name>A0A8T0GBX9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G019900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBX9"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13969">
        <property type="entry name" value="ADCK1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045307">
        <property type="entry name" value="ADCK1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051130">
        <property type="entry name" value="Mito_struct-func_regulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173:SF19">
        <property type="entry name" value="AARF DOMAIN-CONTAINING PROTEIN KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43173">
        <property type="entry name" value="ABC1 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="184"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="585" mass="65088" checksum="1CEDBE8B45DADE0F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBZ5</accession>
    <name>A0A8T0GBZ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein PEP-RELATED DEVELOPMENT ARRESTED 1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G008500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBZ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042644">
        <property type="term" value="C:chloroplast nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038961">
        <property type="entry name" value="PRDA1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37262">
        <property type="entry name" value="PROTEIN PEP-RELATED DEVELOPMENT ARRESTED 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37262:SF1">
        <property type="entry name" value="PROTEIN PEP-RELATED DEVELOPMENT ARRESTED 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="402" mass="43960" checksum="25E362FFF1987BF2" modified="2022-10-12" version="1">MEATRLSSPAQLQSQLQLPFNSHSCDGAHGPARIALRSRLGNVGYCSVSWSSGRRRVGAGVRVRAVAGEEGGPAPGEEGEKEKVDYRLYQALMRGGEEVISVLKEMTELLGDITQIGEKGEAVAVEMAATGAVGQRLDKLDESFLMALDYMIQQADRDDKQRWLLEVIKDVVLAQLSQKFPSQVQIVGILCRTPDKDARQEVLRRCAGGGGTFDQVGGGKTELPAVNLKEVGDQADEIIATMEEKAIVEDRRLLARLVLVREEARSLLSGGVDDDRIEKNKLRNLPEPEVNFLTKIIGLKPGPELHKKLARVLGGEDEGADILDEEKARQIARAQNVARSQIITKKEPPPPVLPVRPGLFIETVNKVLGGMYVTNTAGGVTVQQMEWIRKETLAILQKMAFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG80</accession>
    <name>A0A8T0GG80_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Partial AB-hydrolase lipase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G172800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG80"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000091">
        <property type="entry name" value="Gastric triacylglycerol lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006693">
        <property type="entry name" value="AB_hydrolase_lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11005">
        <property type="entry name" value="LYSOSOMAL ACID LIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04083">
        <property type="entry name" value="Abhydro_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Partial AB-hydrolase lipase" evidence="2">
        <location>
            <begin position="281"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="249"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="700"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="114"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="742" mass="82913" checksum="5ABC4BE577BCE0D4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGC5</accession>
    <name>A0A8T0GGC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G142600</name>
        <name evidence="5" type="ORF">KC19_1G112000</name>
        <name evidence="3" type="ORF">KC19_7G040000</name>
        <name evidence="4" type="ORF">KC19_7G063700</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0590586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="57660" checksum="435E44B1E211C55D" modified="2022-10-12" version="1">MSKNKKQKNVGEWANKFDDMPSLRCKDYIVAFIVEFYQENTLVSLNSRYVRYEEDGPRKFKSEMETKIRNRLMDPCWHSDTQKPGYDHFVSQRAHDALWNAKEVITKYARAQRGGVEAFKDTIAKADCFTRLMAPHSSRKHRRASITWWNSPIGMETAADLRKRHLTILADFAVFYYLDKEVQRGGYATIRRVRIEGNPEIPPYWEFAEKRPLNWSMRPDLARVDHNNESLAIRIPHPGVIRFQAIHQLEHVGFMYWWNGGTLRAMLQRDNEAPGDLPIDYIFRENAEDSPILGKRLQLFRSKRTELAWALCNIIDAVHKYGYLHNDLSPDNILLHFPEDESKIYIGVCDWGLMTKTLENRRSPWVFESVHQKEETMRRRYWVDPRVVYVHKENQDIQIIPDLTVASEDFAAAKIAAKINRGNMCTAYHEAEPVETRHFQNIGELAMVFESYLERVCQNNRGTIGGLGHLINRFRDTHNWPTPIEHYREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH92</accession>
    <name>A0A8T0GH92_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tetratricopeptide repeat protein 5 OB fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G061200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH92"/>
    <dbReference type="OrthoDB" id="423589at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032076">
        <property type="entry name" value="TTC5_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038645">
        <property type="entry name" value="TTC5_OB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26312:SF194">
        <property type="entry name" value="OS01G0506200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26312">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16669">
        <property type="entry name" value="TTC5_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tetratricopeptide repeat protein 5 OB fold" evidence="1">
        <location>
            <begin position="316"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="434" mass="48481" checksum="EB7C45B29A3D91C5" modified="2022-10-12" version="1">MGGGDKADQVLDSKFQGLECHDPMEAVLANIHSLYTVRDTFFPLDPSIKKARLDNLMRDVLLVLDDISSDCRKQPQRRAQWEYLRGKVLDVGPDYCKEAEEHLSKSVKLDPSMVDAWCCLGNCFWKKGDLAQAKNCFNIALSKGLNKKALQQLSMLERRIGKGTADEAETVEESIRHAKQAVSLDIKDGQSWYTLGNAYLTSFFVSGAWDRSKLHQSLKAYQNAEKDDMASANPDLHFNSATVHQYLEDYERALRGFEAASVRDPGLHADHEVNKLINLLSKLEDLVANKGRLKPRRLSSILSSLPIHASVGAHRQALLGDLKEGFNKGMALQAKTLQAVPHDNSVPLFYLVSDREANCFALSVYALRDGAIKEGTTITLLEPFFGEVNVTWQDKVYRYKAVRVDLPQQLLLNGRPPLVQDAVCSTLQAENIPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI48</accession>
    <name>A0A8T0GI48_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G081600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI48"/>
    <dbReference type="OrthoDB" id="1936963at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="346" mass="40122" checksum="B958CAAD3F659748" modified="2022-10-12" version="1">MRNLMYLDHHFCFPSLIKQAREAYQDAMTEQREKDRLDTIAWTTRRAKRVEGKMFVLCHLTNINEFFDYMFERDPENDKLLTVPGLVDAGVDAYRQKFRNAADDLIAKIVAIHNKRCEERRLYELAVKGVLARRDGEGRALLYDLHKKKKKVFQECRADRTTAEPKLMELLKDTDVLLEKLMETEVETYGEINKLWNEFEDTFYETLDHAKNFFADFYGNMRAYEGEWSETLGAASAAIADKYDIGDLEGDLNDVAIALLSDKEVMSNCISASKDGHGLTMDLEEDVKVKAIEALRKSTYEDGIAFMIKRNREKISEIWFIVKKYKDEINSMMQQVLHGDVSSVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIX0</accession>
    <name>A0A8T0GIX0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Large ribosomal subunit protein bL9c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">50S ribosomal protein L9, chloroplastic</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">CL9</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G065400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIX0"/>
    <dbReference type="OrthoDB" id="5555409at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="entry name" value="Ribosomal protein L9, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="entry name" value="Ribosomal protein L9, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_bL9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_bL9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_bL9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_bL9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_bL9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_bL9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="50S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="L9 N-domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="Ribosomal protein L9 C-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal protein L9" evidence="9">
        <location>
            <begin position="72"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein bL9 C-terminal" evidence="10">
        <location>
            <begin position="155"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00035193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0558930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="239" mass="27037" checksum="72B5C1C7FC05DBBB" modified="2022-10-12" version="1">MALSTGALRRLLQQSRSSAAALCRDSSSLQFARSLTTGFEHDRCWGVHEQRHVQNFEVGSGVRHIRTHTKHKVILTSPIERLGKPGQIVSVAPGYARNRLIPNMLALPAIDKFVLMVQNQIKQAGSQIEDTVEKVEVKEETEEERMKAVDVVLRRLAKGRVVLRRDVGMKTTLLKLVTKSDILEEVKRQLGVELHEENMVLESAFSEVGDYDVLLRLPEGLKLPGDKAKMFLKIRIRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM70</accession>
    <name>A0A8T0GM70_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G002100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.100:FF:000001">
        <property type="entry name" value="40S ribosomal protein S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_eS27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_eS27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_eS27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11594">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01168">
        <property type="entry name" value="RIBOSOMAL_S27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0560651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9559" checksum="A593040EBC05CA8B" modified="2022-10-12" version="1">MVLSNDIDLLHPPAELEKRKHKLKRLVQSPNSFFMDVKCQGCFSITTVFSHSQTVVVCMGCSTVLCQPTGGRARLTEGCSFRKKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNM3</accession>
    <name>A0A8T0GNM3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipocalin/cytosolic fatty-acid binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G042900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNM3"/>
    <dbReference type="OrthoDB" id="565904at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000566">
        <property type="entry name" value="Lipocln_cytosolic_FA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10612:SF34">
        <property type="entry name" value="APOLIPOPROTEIN D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08212">
        <property type="entry name" value="Lipocalin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035950205" description="Lipocalin/cytosolic fatty-acid binding domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin/cytosolic fatty-acid binding" evidence="2">
        <location>
            <begin position="49"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="22740" checksum="4E5BF915A8876DEF" modified="2022-10-12" version="1">MGRVSAHVLWLCAVLAMVACFGVGAQAGRTQAGRTLLQSTCANPALPDVNLTAYAGVWYQIGATAVQKSFTETDAVCISGRYSLITSGPNNNAIRIRLDSYNTSSGDYSALIGLLNVNGRSFNLQFPGLPASDYRIIYLKGDPIKDRYKTAMTYSCTTGSTQAINILSRKPTLDGDTIAELVAYAQSLGITLEANNQIVLTPQDAITCGRNDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP34</accession>
    <name>A0A8T0GP34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Sec-independent protein translocase protein TATA, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G142700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011429">
        <property type="entry name" value="PRK14857.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162:SF1">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="121"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="121"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0559964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="167" mass="17059" checksum="D30B837C5CBB79C5" modified="2022-10-12" version="1">MAMAVAGACAGVVSLGATGVRTSGATRAAVPSAFVSSEVHSSTSSGVFSEGRSQLRMVARPVERRQTGGLAVRGLFGLGVPELAVIAGVAALVFGPKQLPAIGKSLGKTVKSFQTAAKEFESEISKAKEPETENENTAIEESPKEEVITSTPIATPKTPENDASKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRA7</accession>
    <name>A0A8T0GRA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G039600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRA7"/>
    <dbReference type="OrthoDB" id="1259151at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13214">
        <property type="entry name" value="PH-GRAM_WBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044852">
        <property type="entry name" value="WBP2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31606:SF1">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 2, ISOFORM E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="207" mass="23087" checksum="8E766908E90B1106" modified="2022-10-12" version="1">MAVNPQLFENGTPVPFVEEIFVLRRDAVDFEADKIAEAPGSKLSGRGTVYLSNYRIVFVLNRPVDGLQAFDLPLVYIHEEKFNQPIFFCNNLAGKVHPVIPEGENRALYAPHFFKISFKEGGTGTFIPLFMNLIKSVRAAQRMAEESQPTAPPAEPLPVASAPVDEMLRHAWIDPSDPSKLYLQQPSESQPTLRRRNYSSAGEAGQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS85</accession>
    <name>A0A8T0GS85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G153800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="31"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1174" mass="133252" checksum="18294F71E4EA8B65" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSC2</accession>
    <name>A0A8T0GSC2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G049300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="12671" checksum="E3DD1ACB1A82B85D" modified="2022-10-12" version="1">MSSPWLTFDGGCPWGSQLCHNVIERHLIGLCQSHCCALFQPQNFIPVLSSSGGAQHFGPPHLSQKMTSTSSGQSNIPTQSTSSGQMPVNSNYPQRPPYLHPWASQMMYSRGSSSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUN9</accession>
    <name>A0A8T0GUN9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G160400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="13001" checksum="0240E91FD634E5EB" modified="2022-10-12" version="1">MLTSACWKRTLVRQTWYYAPVAMSAYQLDSTTFLQDSPPASSCSLPSCPRPQLNLTPSDARIQMHRLRASTDSSTPCKAAVAKSSTQSWKFARPAAIKWKLARWQLPRVTYPHEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUT0</accession>
    <name>A0A8T0GUT0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G136600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUT0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="94"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="651" mass="74865" checksum="0733BA8CD5C8B8FD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV75</accession>
    <name>A0A8T0GV75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G136400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="91"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1095"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1101"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1229" mass="139083" checksum="5BADC5498F536F29" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVU6</accession>
    <name>A0A8T0GVU6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">beta-glucosidase</fullName>
            <ecNumber evidence="2">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G032600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000246">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035793928" description="beta-glucosidase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="529" mass="60662" checksum="076C1DAAA1C745F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWE9</accession>
    <name>A0A8T0GWE9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G048700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="6148" checksum="6EB62B0FBB6441F5" modified="2022-10-12" version="1">MSSNLRLSGNHTSDTDFFCKFLYTLSVQALGFKWIFEANMYITYALQLDRTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWR9</accession>
    <name>A0A8T0GWR9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G156700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWR9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000003">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000016">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000045">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045877">
        <property type="entry name" value="ZFP36-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547">
        <property type="entry name" value="CCCH ZINC FINGER/TIS11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12547:SF156">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="206"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="297"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="176"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="254"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="331"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="34"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="285"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="366"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0562574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="506" mass="52866" checksum="093701A8708C02FC" modified="2022-10-12" version="1">MDTTAAAELGMGEPEGAAFWDAGPPGPDHWGDHGDDELFDDDDGVQHVSHSGFGRGRASGGEPPMKMSRIVADGGHGNGGPSQHSFSGGSSGHGGGASSGRGNASGVAGSPNFGAVGASPSGAGAGAVGRGRGMGSIFYKTKLCSRFRSGNCPYNSNCNFAHGMEELRKPPPGWEEFVASQELPPPPPSQSSGQGGSASSDSQVRFHKTRPCKKYFGEGNCPYGDKCNFLHEEQSVPRAVREAREAAVAAASGSAVFAASPKGESVVPATNGNSKETGGGGVSTPAGSATSNARPSNWKTRLCNKWETTGHCPFGDKCHFAHGSDELQRFVGGLPDSNAPTLSDSKSGGTPSRDSIAVSSHQRHQGGASSARSGSKGNTSWRGPNEISTIYGDWWVEDDDWQCGGTTTSHESTEHEGNVWREAQRRTPLPAPSSSTPKTVSFFKRTDSLESSRQNLSLINGSSSISQQDGGMHKQTFQYEGMNAMGKEGIHGSVLQPEHAWRSELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXK7</accession>
    <name>A0A8T0GXK7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G018800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14580" checksum="15463A9636F099BA" modified="2022-10-12" version="1">MRSLPSFVVRRHRCHQHAHSRERWSERRDARLFLRASATLNAPRILGSHLHRHPPHRAFRQPPHPYISLVSPVHQTGIAPVSPIYHLGLWTHRTARGGCCLCILKVPGGIRTQSLEYRAGIWWVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZL7</accession>
    <name>A0A8T0GZL7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G100800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="15669" checksum="D6A5E307D8351B4A" modified="2022-10-12" version="1">MDSFLVSEGEPINDGHRCFGPGCPGCKTPKSRSRITSHPDSTRTPNHYCVGPGCPKCNIARRRSTLRARSALHKCNTKRTASSMIAHICAIQLVSSFEASPLFDGSSRFLNSDVRVAESSYAPQPEPPHKCTTFPCRVCGKGMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1I7</accession>
    <name>A0A8T0H1I7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G095800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF172">
        <property type="entry name" value="OS09G0423800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="857"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="956"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="524"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="695"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="556"/>
            <end position="566"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0564249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1046" mass="115818" checksum="76AD928C42F9CE28" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8V0</accession>
    <name>A0A8T0H8V0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G013600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8V0"/>
    <dbReference type="OrthoDB" id="190958at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024767">
        <property type="entry name" value="PRP38_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12871">
        <property type="entry name" value="PRP38_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 38 C-terminal" evidence="9">
        <location>
            <begin position="181"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="183"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="185"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="208"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="373"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0568356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="52076" checksum="0108770C5FADB253" modified="2022-10-12" version="1">MANRTDPTARSVHGTNPQNLVEKILRSKIYQNTYWKEQCFGLTAETLVDKAMELDHFGGTFGGNRKATPFMCLTLKMLQIQPEKEIVVEFIKNEDYKYVRILGAFYLRLVGKPTDVYQYLEPLYNDYRKLRRRNADGGYVLAHVDEFIDELLTTEYSCDIALPRVPKRWTLETGGLLDQRRSALEDDFEEEEEKEEEEAAVNGLETMDIDKEHRSRSPVKERERDKERDRDRDRDRDRHRDYRDRGDRDRGDRDRGRDRDYDRDYDRGRDRDRDRDRHHRDRDRDREKDRDLYDRDRDRDRDRDRDRDRDYHRRDRGRDRDRERYSDRDRRRSRSRSRSRERRDRERERGPRSVSPDRKRRRGRAEDDGPLEDGEHRANPDDKKKEKKEKKKEKEKEKKQPVTDGTDHPDPEIAEANRLRAALGLKPLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA85</accession>
    <name>A0A8T0HA85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Amine oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G123900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA85"/>
    <dbReference type="OrthoDB" id="7777654at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10668">
        <property type="entry name" value="PHYTOENE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10668:SF103">
        <property type="entry name" value="PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00469">
        <property type="entry name" value="PNDRDTASEII"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="590" mass="63242" checksum="0CD1946D79B8D647" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAW8</accession>
    <name>A0A8T0HAW8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G162600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000002">
        <property type="entry name" value="AP2-like ethylene-responsive transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000003">
        <property type="entry name" value="AP2-like ethylene-responsive transcription factor ANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32467:SF90">
        <property type="entry name" value="AP2-LIKE ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR AIL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="401"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="8">
        <location>
            <begin position="503"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="111"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="359"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="576"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="661"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="725"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="111"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="192"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="382"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="579"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="592"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="671"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="726"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="764"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0567807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="848" mass="91546" checksum="E5D621009F11DFB4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDI1</accession>
    <name>A0A8T0HDI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G056800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0568985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="57168" checksum="7DB2BB324280874F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDK4</accession>
    <name>A0A8T0HDK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Crooked neck protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G119800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the crooked-neck family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071014">
        <property type="term" value="C:post-mRNA release spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000048">
        <property type="entry name" value="Cell cycle control protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000306">
        <property type="entry name" value="Cell cycle control protein cwf4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000269">
        <property type="entry name" value="Crooked neck pre-mRNA-splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055433">
        <property type="entry name" value="HAT_Syf1-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055430">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045075">
        <property type="entry name" value="Syf1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246:SF3">
        <property type="entry name" value="CROOKED NECK-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11246">
        <property type="entry name" value="PRE-MRNA SPLICING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23231">
        <property type="entry name" value="HAT_Syf1_CNRKL1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23233">
        <property type="entry name" value="HAT_Syf1_CNRKL1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1/CRNKL1-like C-terminal HAT-repeats" evidence="10">
        <location>
            <begin position="84"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA-splicing factor Syf1-like N-terminal HAT-repeats" evidence="11">
        <location>
            <begin position="335"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF23233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="717" mass="85362" checksum="65B09BD7082CCFB6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFL7</accession>
    <name>A0A8T0HFL7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G089000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFL7"/>
    <dbReference type="OrthoDB" id="416344at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050585">
        <property type="entry name" value="Xaa-Pro_dipeptidyl-ppase/CocE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43056:SF5">
        <property type="entry name" value="PEPTIDASE S9 PROLYL OLIGOPEPTIDASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="20543" checksum="D2389FDD8E6FE4D2" modified="2022-10-12" version="1">MGLKEPTEAPFGSWKSPLAAEFVSGAPERLEGAVVDFRGRLPWLEGRPSEEGIKCSRAVLVMGGDRPEDVTPAGFNVRATVHEWTGGGLKLVNRVDQGDIVVFSNFADQSRLLMVIGVPLRLLRPTKCSSQFATQTGIMMPSSTASLFCGKVSIVLAGDEFFRVKVVMARVYIIKGEVQLEVVRANFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGF9</accession>
    <name>A0A8T0HGF9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G087600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7588" checksum="7030E524A23A8B30" modified="2022-10-12" version="1">MMATRKTEKSPVRIQNRSAGKALGDLTLISFESKCYSYFLIINLMAFLLLAPRGPSAVIQFLLRPSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHN4</accession>
    <name>A0A8T0HHN4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G040500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009975">
        <property type="term" value="F:cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051762">
        <property type="term" value="P:sesquiterpene biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045:SF30">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="537"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="620"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="668"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="678"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="721" mass="79974" checksum="BBC468C27146EFAC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIF3</accession>
    <name>A0A8T0HIF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G081500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035848064" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5721" checksum="8C661C384D33E101" modified="2022-10-12" version="1">MLCHWVISARFWTLSPLPLSACVCSCAENLLNTGWIVAKVWELCYVNTYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJI7</accession>
    <name>A0A8T0HJI7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G200400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12710" checksum="9A86DD6F99184A11" modified="2022-10-12" version="1">MAMPCPRQVAMQLPLPAPGGPELAVKLASTQPMHQTIPKSYPNHPQTRHTSSATSAASATSTRVSIRQTLPLITAGVSASEKLWHSSRVPPTRRDSLARQLPALDAQLQLLNDMSYSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLL5</accession>
    <name>A0A8T0HLL5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG035900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLL5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5691" checksum="2EB8B51CA05449A0" modified="2022-10-12" version="1">MLDAFPTEGLWLMAASMGPKAVFRCLYHFKQKCMHLLGTLLSTRKCLFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNE6</accession>
    <name>A0A8T0HNE6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_VG089900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CONSTANS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010402">
        <property type="entry name" value="CCT_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717:SF45">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06203">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51017">
        <property type="entry name" value="CCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="10">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="CCT" evidence="11">
        <location>
            <begin position="491"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="134"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="134"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="152"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="163"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0572374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="548" mass="59994" checksum="C50B0A96759CAC56" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNW9</accession>
    <name>A0A8T0HNW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG106100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045703">
        <property type="term" value="F:ketoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05356">
        <property type="entry name" value="17beta-HSD1_like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000137">
        <property type="entry name" value="Hydroxysteroid (17-beta) dehydrogenase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051019">
        <property type="entry name" value="VLCFA-Steroid_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43899:SF13">
        <property type="entry name" value="RH59310P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000126">
        <property type="entry name" value="11-beta-HSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0572564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="325" mass="36481" checksum="9752A038FD6D56DC" modified="2022-10-12" version="1">MVLWRFVKVFVMGAVLEDRMLLGLAAVGFLYILRLVYLVVPWFYAYFLRPAKPLSRYGEWALITGSTDGIGRAMTVELARKKINVVIVGRSPTKLDELSKELTSKYKAQVRSVVVDFMDDDLEAGLAKISQATSDIQVGILVNNVGISYPYARFLHEVDENLEKSLLRLNCETTTKMIHLFLPSMLKRKSGLIVNVGSGAVGILPSYPLYSVYAATKAYVEQLSRSLYVEYKHSGIDVQCQAPLYVATKMSKIRASFTAPSAEKYAKCALACAGYEPVITPYWVQSVMWFIIRLLPEPIMDSILLSKNLNIRRKGQAKENLAKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP34</accession>
    <name>A0A8T0HP34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF427 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG104600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="entry name" value="Domain of unknown function (DUF427)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34310:SF5">
        <property type="entry name" value="DUF427 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G02220)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF427" evidence="1">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8606" checksum="FDC76411105511CD" modified="2022-10-12" version="1">MATKAIWNGAVIAAMDNYEVVEGNVYFPPSSINMQYAKPSSTHTTCGCAGWKGQASYYTIKVDGKQNKEAARLRGSTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP42</accession>
    <name>A0A8T0HP42_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG118400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="189" mass="21933" checksum="E2026AB76ED202E5" modified="2022-10-12" version="1">MALAHSQGLPMPPRTIVTNIAGEIMGQRTRWHRAVREIAKRTLDYSVREHKKYPREWKWTIDTIQKELSGMFTFDHIPVRRDVLGKYVAGFIANDRSKWKAHSIENNYSKYPECPDEAFQLLDKYWKSTEGQLESEPMKEKRSCVGTTKNLEFLSSQSSPPTSKRSKQQAIQDYMASDSENQYIIQTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPG5</accession>
    <name>A0A8T0HPG5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG117500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="95" mass="10801" checksum="9DE2FC54C3BCA51D" modified="2022-10-12" version="1">MMTSMATNPIENPVLFHTIGRKSSRSPMALIEEHKVEVAAMWYTLPPKDNPSSAKPSPILRPPPSKKKLAPHGHDSHQELKIFRTQIFPHNDFQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRP6</accession>
    <name>A0A8T0HRP6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG198000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="10908" checksum="F7A5A7AB96EEB61C" modified="2022-10-12" version="1">MHQMAESRHFRQPLLRLPLVKCIAIEEYDGHPRQERSLLLSATQTPSYSHECTKKVGVTAYKFRRKPKSCRRRLTKRQSSPVYHHQANPLPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRY1</accession>
    <name>A0A8T0HRY1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG206400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="9133" checksum="1664DD76F7FA4A92" modified="2022-10-12" version="1">MYNVDEGNLIKPPCYVTSHPRSNLESVPKRSGYFEKACLTCSTKHNYVFRSRNRKEVPLNNQEQQQSSELIQDEGCHCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS47</accession>
    <name>A0A8T0HS47_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SKP1 component POZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG198600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS47"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016897">
        <property type="entry name" value="SKP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016073">
        <property type="entry name" value="Skp1_comp_POZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11165">
        <property type="entry name" value="SKP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03931">
        <property type="entry name" value="Skp1_POZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SKP1 component POZ" evidence="2">
        <location>
            <begin position="5"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6154" checksum="79BAC8483F14BFF6" modified="2022-10-12" version="1">MAEKRVKLKSSNDEMFEVDEAVAFESQAVKNMIEDTGIDAPIPLPNMSSKIWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSU4</accession>
    <name>A0A8T0HSU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG234100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="16429" checksum="29105F54504791BD" modified="2022-10-12" version="1">MYIYIYIYIYIYIYIYIYIYIVIGHIYLFIFYSFLHSPTIQFPLLSLFPTSLFPSTFFSIFISIVDFLFFVFFPFFLLQCLHIFILFRVPVLVGLVLLLSPSFLSVVLIFVFLPSSVFPSDLLLILLLLLLLSFLLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSZ0</accession>
    <name>A0A8T0HSZ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG195900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="16620" checksum="F64D8B71B642F72B" modified="2022-10-12" version="1">MEACQRDWALQCGIVRRFGCVFGGVRLELLGGAPNLLPDLRLLQTQVPSELGLPHVGRFPAVDKMCGGNSDVDDTLSPGFGKLLLLAATKVSNQSVVAFRVTPIDQSSGRVAAACSIQIQFAALSLCRAGLLYSQGIGAPHLRMWIGFRAHRGGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT25</accession>
    <name>A0A8T0HT25_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG201300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="225" mass="25192" checksum="34918087A9C71781" modified="2022-10-12" version="1">MDAETHVANIQGHGSMAMFHVSQRSQPTRYNGHIQTKSNCNSVSPYGCSNLGALRDEERVRLELLESRLLGCEDSKIAMESRLDFIQADVSSTRIAMQELIAIIKKTAAASREPRATLHHVLEVEDIFPQKSVTQNVGKQSHSTATTDTAIPPPDQVTKISSTVPMCLQTLTEGGFICLFNRAHHWHLPVKTPIMAWPTWRFKPILLVSTLQHVDIWQILPLGHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTU0</accession>
    <name>A0A8T0HTU0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">OTU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG237800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C85 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTU0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22797">
        <property type="entry name" value="OTU_plant_OTU5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000014">
        <property type="entry name" value="Cysteine proteinases superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050704">
        <property type="entry name" value="Peptidase_C85-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419:SF10">
        <property type="entry name" value="DEUBIQUITINASE OTUD6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12419">
        <property type="entry name" value="OTU DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OTU" evidence="4">
        <location>
            <begin position="193"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="136"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="53"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0574145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="37757" checksum="02A40AC0E34CC29E" modified="2022-10-12" version="1">MNCNQLPQVQRQAHAAAGAAAATMDASSAEPEYSPVEDVRPKEEAMVTRSEMLSRHQKEVKELQGKEIALKKAAAKGSKAEQKAKKKSAEGEIAKLDILMKARQAKELASLGFKGEQKEEAASIDTLVRAIAGVTASGSGEQARPSKGQKFREKRAQQAADREQRIQEEKINLVDPRVVEDQQLNIKLLPLGLGLKEIKPDGHCLYRAVEDQLTLHLDTCSIISYQQLRERAASYMRSHVEDFLPFIGGDVEREIECQDPQSKYETYCREVEATASWGGQLELGALAQALRKHIVVYSASGPDVEMGKEYVNENLTIRISFHRHAFGLGGHYNSVVPLLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTV1</accession>
    <name>A0A8T0HTV1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG240200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="19922" checksum="82CE276DFD8FCAC8" modified="2022-10-12" version="1">MDRVHKGYLQHNDISPGNVLLHFPEDKVSEVYIGVCDWGLASRVCETTPSRYGYPTAEARTAAFKERGTFVAPELWYTYGKPNLETSYETLRQRHLYTQVADAYSVGVVANKIWDNKDDFDLFKDAAGKARFAVALKELTNPDPKNRSTLQLVHATLTAPPYNFQISECCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUD7</accession>
    <name>A0A8T0HUD7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG260400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUD7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="44"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="14289" checksum="B70C1E75AB8A9200" modified="2022-10-12" version="1">MLLVSNVLSEDAPCPRQSKTDDKGRITKNQGLTRPENLKLQVKNYNQNYSRSYRSSNRDWHNTQAEPSTVSKEAKESKNTNRKLYSRLNPRVIPGEHNPTTLLTKRQKLHIVTQTRNALKFAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVS6</accession>
    <name>A0A8T0HVS6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG304700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14422" checksum="4415968F79AD6238" modified="2022-10-12" version="1">MTQVYFVDDVTDMEWKVVRLKEPRSRRALELVDDDFLSASGSSEATHQINRGLRDTARRMDNGGESVLRADVVEGTNREDASDDDDEEAYGEFDEEQDNGPVQGPLVPDADSTQHPLPHPGDTDDFDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWA9</accession>
    <name>A0A8T0HWA9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG284300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWA9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="9194" checksum="860A39D22A061210" modified="2022-10-12" version="1">MMCLQFGTEQRNNKHIQLRHEVRCMFMTEKNHIGPVYSANLLGWRMTTSRRITTRGTIDYGGRGENYLFVTIKRDVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWV4</accession>
    <name>A0A8T0HWV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G016800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF15">
        <property type="entry name" value="PROTEIN NDH-DEPENDENT CYCLIC ELECTRON FLOW 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="412" mass="44590" checksum="A3064390B34CA1E6" modified="2022-10-12" version="1">MARLGALSQCTQAPNTSSFCSSAQGDCRSGRIGSCCRRIGSSCGRWLSVDELKLEQKLGDCGREERRSKSGGVHCSRVAAEAAEVVPWSEDLEERFGKSGGVKFVEVAGYRIVEMRLKEGSSARVLLQSALVSSYKSRMWHGGLEELLYTAVVPGEDELTTVGGVGLRVWEGEAGSELDFAPTECWDVEDVRSDPAQFVQVALSTTSKGRSAGAMLEFKYVLTLTKASLSCALVTTNVGDSAVSIHGSLETTVAVNFVDGVYALGLEGCKYLPTAPKPSPGALEKATKTENGLFSRLGWFSGGEGDTKRNDSTRTGNEMFVEEEMVRMKGGFVRLYPDASDCVSLLDRGKRRTINFNNTGFGDIRLSNPGEESGLEDWESFVCIELARSIQPVDLQPGQEWRAAQQLVNPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXC9</accession>
    <name>A0A8T0HXC9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">26S proteasome non-ATPase regulatory subunit 4 homolog</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">26S proteasome regulatory subunit RPN10</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG312500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proteasome subunit S5A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008540">
        <property type="term" value="C:proteasome regulatory particle, base subcomplex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01452">
        <property type="entry name" value="VWA_26S_proteasome_subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000005">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.3990:FF:000004">
        <property type="entry name" value="26S proteasome regulatory subunit N10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027040">
        <property type="entry name" value="PSMD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10223:SF0">
        <property type="entry name" value="26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="6">
        <location>
            <begin position="79"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="319"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="451"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="319"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="480"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00044341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00071116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0575038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="51009" checksum="963C98A4C7A88AC7" modified="2022-10-12" version="1">MIENVGKNSSNPLLHSSKLFFSVRQSCPKNRVSRTKTHNCRSFSSSEASLRSDRLCASIAPSPSFQFPSPASANMVLEATMVCMDNSEWMRNGDYVPTRFQAQADAINLICGAKTQSNPENTVGVLTMAGKGPRVLITPTNDLGKILQALHGLEVGGEMSMISGVQVAQLALKHRQNKHQRQRIVLFAGSPVLSEKKTLESMGKKLKKNNVALDIVSFGEDDGEKVEKLEALLNAVNSNDNSHIVHIPGGDRVLSDVLISSSIFTGDGEGGSGFAAAAAASAAAAAVGGGGGAYDFGVDPNLDPELALALRVSMEEERARQEAAMKRSAEDSTAKGQQAGESSSVPDVAMSDAAPVKITDKSSDMMIDDDTALLEQALAMSMAEAAQAAAAAGGGAAVTDTSMAESGGDDQDLAYALQMSMQEAAAAATAAQGSADVNQVLGDQSFVSSVLSSLPGVDPNDPSVRDVLASLQAEEEEKNEDQAGKDKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2A3</accession>
    <name>A0A8T0I2A3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G101800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2A3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061458">
        <property type="term" value="P:reproductive system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47149">
        <property type="entry name" value="F-BOX PROTEIN RMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47149:SF1">
        <property type="entry name" value="F-BOX PROTEIN RMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="61"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="38331" checksum="F2F4B10F600B6FC5" modified="2022-10-12" version="1">MDRVEAAGMGSAMGAFVQTDVTPAPTSSGRRSFQTTCARMFKCRKTRASSSKKSKREPNWFNEDIWICIMSCLDAKTLLRLAVTSRQFYALVKDDVIWKSVFLRDIPTLSIDMRPAFSWMSLYLAACDGRHTFSYHDSEKHIDWMRIGVFCLDSGEAVATDRLKDMKQVSEATDTLQSDSILHQTYSISNVKKGYWIADLHLVHCPVCNLATCEGTMQALDVRHWELFLNNEYKTGEWRYEQVHTRHVAGHCDEAAACVFDANQLRSKGTQEVLDMSKWIAAPGNWVPRGITSSHGAASCTNLHLNKGVHSWHAIPMTINVLTKPVFHRRPLFIYSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2Q5</accession>
    <name>A0A8T0I2Q5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G146300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2Q5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11662" checksum="DBFD24F414A0EE86" modified="2022-10-12" version="1">MTLSSTSVTRISSGTSSRRLTKLTLIALMIFMVVVIPGIVPTLIMITLIGLISDLAMTKERAPQELAHSEACQFLGGARPHKLLQLLCDRNLRCTVSEFRCYIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2R9</accession>
    <name>A0A8T0I2R9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G129900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2R9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035733293" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="7302" checksum="9814B8886AF18219" modified="2022-10-12" version="1">MVFILWQLACTACLVIGSKVRIDLQRVSEDVNEVRMMCECLWYLYFGVLDVMHMVLDVLLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4G8</accession>
    <name>A0A8T0I4G8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G193800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4G8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="384" mass="42872" checksum="AA08D45E6B5B9CC0" modified="2022-10-12" version="1">MSYDEDAGAEVEEGAGAEVEEGAGAEVEEGAGAEVEEDAGAEVEEGAGAEVKPLAAVHHPSNEEHKLPDLDYLPNWRGGRSNPYRIEAVSGGLFLFYYYPSGLSSSDLYVVNPLTRKWRKLSRGNCCQELGWDYLHAQMVVDENVGAYTVIVLADNCVNVYSSHSKHWVCNPVQYSTGIHDPFLPLGGAKSRFQSSACVDGYVYVCSRICRDQRRRSVVEIQMFPIQPVAEQHPTRSPTVVNLGNFRKSDIYFGSPYLNLASPTLVECMGGIYIVVCNCEMFETSQNSIPGVVPGVVPGVVPVVMRRVIHIFKFQEGSKICPLHVHYVSERKLLGRRIFSVLWNRRDDFSCTAKSSVIWVAWENHLLQYDVDRLQRLEGWLPLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6B6</accession>
    <name>A0A8T0I6B6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G031800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6B6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005134">
        <property type="entry name" value="UPF0114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721">
        <property type="entry name" value="OS06G0710300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31721:SF1">
        <property type="entry name" value="OS07G0656700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03350">
        <property type="entry name" value="UPF0114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="296" mass="32244" checksum="0D5DE1FAE04B2DFF" modified="2022-10-12" version="1">MTLLRAHTRLVSNPLHLSSSPGLGRGVSSSQPGIGRRLHHRSVVFRCCAVSVGNGGFENSRDGGLLAARDGGSPSRVTNSSASNQNHAAQAPIVGSSSDSAARGNSAEETWTMRAESTIERAIFDFRFLTLMAIGGSLVGSLLCFLKGCGFVIESFIAYYHMCLNGRHTGKVILRLVEAVDVYLVGTVMLIFGMGLYGLFISNNIEPNDTQNDRALKNTTLFGMFPLTKRPLWMRITTLDTLKTKLGHVIVMILLVKLFERSKTVHISSAMDLLYYSISIFLSSASLYVLQRLHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6Y1</accession>
    <name>A0A8T0I6Y1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G010300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6Y1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="62" mass="7038" checksum="65B4349EF4A9BE10" modified="2022-10-12" version="1">MKMSIMCAASAMTPKLDHDPDYATTHAGLPPRWGYPQRESRLGLRSGRRRLNRTTKVVMLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7T4</accession>
    <name>A0A8T0I7T4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G026200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the kiwellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7T4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd22270">
        <property type="entry name" value="DPBB_kiwellin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.10">
        <property type="entry name" value="RlpA-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039271">
        <property type="entry name" value="Kiwellin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036908">
        <property type="entry name" value="RlpA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33191:SF58">
        <property type="entry name" value="RIPENING-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33191">
        <property type="entry name" value="RIPENING-RELATED PROTEIN 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24300">
        <property type="entry name" value="KWL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50685">
        <property type="entry name" value="Barwin-like endoglucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035923780" evidence="5">
        <location>
            <begin position="26"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0578483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="24839" checksum="A1F7F927BE698C6C" modified="2022-10-12" version="1">MASRGSQLILGLFLVGTLLIPRIHAQTPKGCYQSCTNDNQCEGRLACMSGKCNDDPGVGTHICSKAPPPPPATCKRYGYITAGTITSNECNPNDVPCCVTGHKYGRYACSPPITSPATTATMTVNSFAAGGDGGGPGACYGKYYSDSERVIALSTGWFNNNSRCGKTIKISGNGRTTTAMVVDECDSQNGCDAEHAYQQPCATNIVDASAAVWAALGVSTNDDRYGYMTVTWTQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9S3</accession>
    <name>A0A8T0I9S3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G117700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9S3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035746910" evidence="1">
        <location>
            <begin position="27"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7963" checksum="7771A937FE6F9EC5" modified="2022-10-12" version="1">MNCWPRVCSFFVLFLSTFLSWEIALARDAKEIITPCKQAHPLCRKQISQCTRVSPVRCSILEHCSHVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAD4</accession>
    <name>A0A8T0IAD4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G120600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NFYC/HAP5 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAD4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22908">
        <property type="entry name" value="HFD_NFYC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000006">
        <property type="entry name" value="Nuclear transcription factor Y subunit gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF54">
        <property type="entry name" value="CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="8">
        <location>
            <begin position="82"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="208"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="232"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0579751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="258" mass="29635" checksum="97063E3E82C9C016" modified="2022-10-12" version="1">MATQHPHIPPSSAPQMAQHPGSVMPIQMHYPQPGQQQMMPQLGDQQMQPQLHYQQIQKQQLSQFWTAQQQEMEQVNDFKTHQLPLARIKKIMKSDEDVKMIAAEAPVLFSKACEMFILELTLRSWIHTEENKRRTLQRNDIAGAITRGDIFDFLVDIVPRDELKEEDLGVPWSGVAGDPGVQYGGMFYPGMPGQQMHHPMGAPEMMVGQPPIPPNAQMMYQPPPQAAFAPEQQQQQQQQQQQQQQQQQQQQQQQQQMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAV9</accession>
    <name>A0A8T0IAV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G136500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16970">
        <property type="entry name" value="Alpha_kinase_VwkA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:001043">
        <property type="entry name" value="Alpha-protein kinase vwkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.410:FF:000135">
        <property type="entry name" value="Alpha-protein kinase vwkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.200.10">
        <property type="entry name" value="MHCK/EF2 kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004166">
        <property type="entry name" value="a-kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052969">
        <property type="entry name" value="Thr-specific_kinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47763:SF4">
        <property type="entry name" value="ALPHA-PROTEIN KINASE VWKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02816">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00811">
        <property type="entry name" value="Alpha_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51158">
        <property type="entry name" value="ALPHA_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Alpha-type protein kinase" evidence="5">
        <location>
            <begin position="873"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="187"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="190"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1117" mass="122681" checksum="7409DC1C9009C7B0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBD7</accession>
    <name>A0A8T0IBD7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G195700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBD7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="36" mass="4173" checksum="7EF427085BE763F2" modified="2022-10-12" version="1">MSSTHNLSASSFVLIYRLLRLSFLAQNYVSDFCIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICV3</accession>
    <name>A0A8T0ICV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nitroreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G234600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitroreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICV3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02136">
        <property type="entry name" value="PnbA_NfnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="entry name" value="NADH Oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050627">
        <property type="entry name" value="Nitroreductase/BluB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23026:SF90">
        <property type="entry name" value="IODOTYROSINE DEIODINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23026">
        <property type="entry name" value="NADPH NITROREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="FMN-dependent nitroreductase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="5">
        <location>
            <begin position="17"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="226" mass="25219" checksum="87705859194BD76D" modified="2022-10-12" version="1">MTMAMEQQHHYDLEATIRERHSTRKFHSTPVPRALLMEALSLAQCAPSNSNIQPWHLFIAEGVRRDRLKEALLAECKRAPPTVPLLPEEFKHYRQELGAKVYGSMGIAREDKQGRAVAVMRNWEFFGAPVVAIVCLHQDLGWADAMSVGMYVQTLLLGLTARGLGSCCEVSLAAYPDIIRKELGIPPELVIICGVAIGYTDFDFPANRLRVERAPVEHNVAIIDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID06</accession>
    <name>A0A8T0ID06_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Major facilitator superfamily (MFS) profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G198400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID06"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17328">
        <property type="entry name" value="MFS_spinster_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505:SF78">
        <property type="entry name" value="MAJOR FACILITATOR SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="SPINSTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035796507" description="Major facilitator superfamily (MFS) profile domain-containing protein" evidence="8">
        <location>
            <begin position="19"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="314"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="427"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Major facilitator superfamily (MFS) profile" evidence="9">
        <location>
            <begin position="10"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0580776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="482" mass="52222" checksum="E13B83C1D9D6CB97" modified="2022-10-12" version="1">MKLLWGLTLSLFLINLAAILERADESLLPAVYKEVSEAFQASPSELGTLTFIRTLVQALCSPLAGILAMRYYRPSVIGLGTLFWAVSTAAVALSLTFTQCAFSRALNGMGLAIVVPALQSFIADSYTESGRGVAFGWLNLVGSVGGIAGSTTATIMAGYGSIWGVAGWRVAFLLVACVSCVIGWLVHVFVVDPRDISSAGPGGHRSMDGRSVSRFKTEEKVGKSIHSAWLDSWIAIKAVMKVRTFQIIVMQGLVGSLPWMAMVFFTMWLELIGFGHKAAASLMSIFSAGCAIGAVSGGWLGDRAEQKFPGKGRIMCAQFSSFMGIPCSLVLLHVLPQDPERWGLFASMFVFMGLTISWCQACANNPMFADVVPEQQRTVIYSFDRAFEGGFGALAAPLVGILAERVYGYRTHMVIPKDGSPAEALALSRGLFAVMAIPFGLCCLCYTPLYFTYSKDREEARAHNSKHAYNPIWDEELSLREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEJ7</accession>
    <name>A0A8T0IEJ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G208800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0677 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011610">
        <property type="entry name" value="SAM_mthyl_Trfase_ML2640-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00027">
        <property type="entry name" value="mthyl_TIGR00027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF8">
        <property type="entry name" value="LEUCINE CARBOXYL METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="42546" checksum="E9263A34B9F285AC" modified="2022-10-12" version="1">MPSLLLHMCSPSPAWSPRFNPGRCSIKLHDILVSMSVGKAQHLPAVVDSSSDDDDMTHGPGRLGVNLATSQCQIEAVRRLHNSLDPERDYLERSACQTAAGRALWNHVIHDPLAEVFAGDALLRGLQEKVRRDQDKNARETAGVMMAVRTLWFDARLAEALVRFDSTSTHQVVLLGAGMDARAYRLRSLKDCSVFEVDSAKALHLKESILQAMVEAGEPLPRLEAKSLHRVASDIATEDWFGRLTAAGFNVHLPTVWILEGFLYYLQEVRAKETLRCISDHCMNETVVLADFMNESSTHLAHELKTHFYFHSDWPEELLPKLGFPQVKVSQIGDPDANFGLINDELNLFHQTRRVSRHVKADVNGNPYRRLLLVESWAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF13</accession>
    <name>A0A8T0IF13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G254200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47474">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE RLPH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47474:SF1">
        <property type="entry name" value="TYROSINE-PROTEIN PHOSPHATASE RLPH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="322" mass="36060" checksum="FC4D57F17675F839" modified="2022-10-12" version="1">MVKRVTICVGDIHGHLGRLQKLWGNLELKLGAEAFGDATVIFLGDYNDRGSDTKGVLDFLVSLPRRYPQQRHVFLCGNHDFAFAAFLGVLPAPPSADIDYPSTWDEFQPHEKREGWWSGPGQEDIHLQGRRWAGKITVEYNTTRGENYKGSIYDARPTFESYGVAHGDRAGLIAAVPDDHKEFLRNLAWVHEQEGEETGDPETSYSKLIAVHAGLESKSVDTQMQMLQTKDAQHPRIEPLAGRKNVWNTPPELAAQNVLVVSGHHGKLHFESNRLIIDESGGFDHRPIAAMILPARELVRDTDDLLESKLQEPQLQPILVAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFU3</accession>
    <name>A0A8T0IFU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G245100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="222"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="41824" checksum="9749BA2085518478" modified="2022-10-12" version="1">MAPAAGEILVPEVSAGVGKAQHLGDGLGHHSFFEGDKHNVQEFVLPEALRFDSAFDNFVDDAEFPVIDLSTLASGDEKQRQETIARLAHAAETWGFFKVVNHGVPLELIQRILEQVRGFFAKPIEEKLEMKSDMPRSYFGYTPGTMITDVDGQHPSWTERLYFKRKEDLFRKLAQGAWPEDDGRISEAILKYMDHMDALTEQLFELLTEGLGVKSEKLTAFHDNTCGGFNVAHYPACPRPELARGLRAHTDPHTMAVLYQEYPGLQLLKDGKWLTVRPEAGTLFVNVGDILQIWSNGRYQSVQHRVALNPTASRYSLIFFKNPRLESVISAPSELIDEAHPRKYKAVSWAEYVGMISKGTTKPGLLIDKIAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFZ1</accession>
    <name>A0A8T0IFZ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Transcription factor MYB44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G010100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFZ1"/>
    <dbReference type="OrthoDB" id="2143914at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000060">
        <property type="entry name" value="MYB transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050560">
        <property type="entry name" value="MYB_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614">
        <property type="entry name" value="MYB PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45614:SF82">
        <property type="entry name" value="OS01G0977300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="15"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="15"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="8">
        <location>
            <begin position="67"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="9">
        <location>
            <begin position="71"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="124"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="223"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="161"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="286"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0581796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="51059" checksum="9979DC7D6A3B35A7" modified="2022-10-12" version="1">MAMTGAQRSSAAMEEFDRIKGPWSPEEDAALQQLVDKYGARNWSLISKGIPGRSGKSCRLRWCNQLSPQVQHRPFTAMEDATIIQAHSQHGNKWATIARLLPGRTDNAIKNHWNSTLRRRHLAERSSRTDCVEQQLSHVGRVGAPDEEDIGSVDGRKRSSNEISTDGSVQEESGWEADSHKMKRMHIGAESPPCVSPRELPSNVMQAPQVFRPVPRSSAFASFSPNGTFAPPSCERSRDSDVSEVNDPPTSLSLSLPGSSPPRKEQSSTEDSPLVRQASVVSHVPVNKERPSSPDLPMHGRWESRPAVDQPFQDQFPVAPYPVHTATMPSQIPGLQHPQSLSVVPPHNGYAPHGNSATAEMMSVAVRSAVAQAFSPVFQAQGAQPWATSAPQPAPPLSYGLDAAVNTGLVALMRDMVAKEVQKYMAAVHSSSCAPYYPTFGPDHAAMGAHSKYSGQADFLGSMATSAARKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG50</accession>
    <name>A0A8T0IG50_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G025500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008889">
        <property type="entry name" value="VQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039609">
        <property type="entry name" value="VQ_15/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33179:SF83">
        <property type="entry name" value="VQ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33179">
        <property type="entry name" value="VQ MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05678">
        <property type="entry name" value="VQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VQ" evidence="2">
        <location>
            <begin position="192"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="42414" checksum="B26F313B0C6B9173" modified="2022-10-12" version="1">MGVQTYIPRDHQDILQVENATSRRRADCGTDIQPFGGRGVSTIWLEDDGSSAAIMADWPWESANASSSDQQASPLVQGSPLQSSSSQSSHEAMQRTSQEFMQPPLDALGLGVRTTSSRTSLVETLQTCLTSLPSPTNAPALASPTGGSLSDPSGASTPTLQQSRSAGALSGSTSKALGPAKPTKRRSRASRRVPTTVLEATSSDFRDMVQRLTGVSAANSAAPVRPQPQRAAPTTFIRPDRPLPSATVIRPAANSSMLNLSTPTTSLESNVASFDDIFHILQRSSSELFAPLHSSNIKREFHQAESSVQPFSMSGSIMATRPLLTPSNTTWTWESAAHEQSRHFEFPNASSSLAFANEIIGASGEANVSSTSGLIVLPDDNDLSSSPFDISWLPGHDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II58</accession>
    <name>A0A8T0II58_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G069100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11819" checksum="0E7C797DD3360DB8" modified="2022-10-12" version="1">MPWNVYWLARSIGLSSYLKTLHDLQFKARGWFLKLSYRVCEFDYSCTCSSADTIHVGIRMGQRQAEQCVERVTRSKADYGMMIFADKRYAGHSCSNFHPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ60</accession>
    <name>A0A8T0IJ60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_3G065200</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ60"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000233">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase TDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000192">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase RPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001656">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974:SF61">
        <property type="entry name" value="LEUCINE-RICH REPEAT (LRR) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 17" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035932665" description="Protein kinase domain-containing protein" evidence="17">
        <location>
            <begin position="23"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="723"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="792"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0582503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1089" mass="115261" checksum="4153DC97095CD75B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILW9</accession>
    <name>A0A8T0ILW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G173100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8524" checksum="3B78B3EA8228F18E" modified="2022-10-12" version="1">MNIPDAPTLNTDIICNLYIELLEMTPLAPMSCRFSRRRGCATCSQSELSSCCRLMTDFAVFETWRTISPFHPYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM13</accession>
    <name>A0A8T0IM13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G182100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000095">
        <property type="entry name" value="protein STRUBBELIG-RECEPTOR FAMILY 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051564">
        <property type="entry name" value="LRR_receptor-like_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48055">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR PROTEIN KINASE EMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48055:SF22">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE SERINE_THREONINE_TYROSINE-PROTEIN KINASE SOBIR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035927618" description="Protein kinase domain-containing protein" evidence="9">
        <location>
            <begin position="27"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="224"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="121"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="465"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0584065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="59355" checksum="C27635C5057A3D27" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM31</accession>
    <name>A0A8T0IM31_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G237700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="447" mass="50820" checksum="99EB18DE86957927" modified="2022-10-12" version="1">MGDLQAPMEWLRRLNSTGELAGKVSGAWGALQFDPELADSLPLPVVAAIDRCKNAFAYRDKGAITREIHLFYLHHDDVLAFLDRQRNFEGLVEQVHKNRAAFVAERLSAYDIKIRIEEEDEEWVWSPLFREFKCEPQPRCLSRPYEHSEDEFEGLVKWIEMEGGRIGEKNEPPHMARALKLFAKSELGSRMPMLCPVLGLTQETLKDRGEQILIAMEELIRVGKIYFPTMDIESVSFETFRLVLDDCIDRRGEVAQYHCWGRDTFVRACLDMLALDKKSLLRDMWVTREGVDFEAVSNAFRTVLLYRENLDLGYIFGSLEATGIWPAAGHGLFRAAKELLQDSLHHLHGKLQVWNVTEDLEDLDAWKASQVLCTIDQLRIFGQAHVAAPSIQPEESSPSDRSDPWDFSLSPRESLKKHGEDVPDPVVAPGLEVEAASCDPVVELPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM91</accession>
    <name>A0A8T0IM91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G177000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11900" checksum="EC372C6A0FE57064" modified="2022-10-12" version="1">MRCHITRAEVRRTATQDVASICRRRVSVCSLETSLIHRPSDASSTHHELRKRRSEADPELVPDRCRLYSMPVTRSSPDYLTRPLLVLQIVSKLLHRSSTWYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMS8</accession>
    <name>A0A8T0IMS8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G203000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080032">
        <property type="term" value="F:methyl jasmonate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080031">
        <property type="term" value="F:methyl salicylate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009694">
        <property type="term" value="P:jasmonic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009696">
        <property type="term" value="P:salicylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045889">
        <property type="entry name" value="MES/HNL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10992:SF1032">
        <property type="entry name" value="METHYLESTERASE 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10992">
        <property type="entry name" value="METHYLESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="29085" checksum="12B18430D5D1E89B" modified="2022-10-12" version="1">MEELKPNQQYHFVLVHGAQHGAWCWFKIIELLEQAGHRATAVDLVSAGASTVGADDVKSFDHYNQPLYELFESLAPAHKVMLVGHSMGGTTVARATERYPHKIHAAIYVAGAMLTSGMSQSDNHEEVFRETSRNAQLNFGNGEHNPPTSCWPSLEIVKQAYYNCCSSEDIEFASKLLKPLPIMGDDATTFTKEGYYSVPRVYIRCSLDKALAPRFQDRYILQNPPTSVLHLETDHSPFFSAPRELHQHLLSVADTYASQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPV5</accession>
    <name>A0A8T0IPV5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G252900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000222">
        <property type="entry name" value="PP2C_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01032">
        <property type="entry name" value="PPM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="10">
        <location>
            <begin position="77"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0585039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="358" mass="38116" checksum="3E66CFACD210230A" modified="2022-10-12" version="1">MAMTLQAAASGCHAMAPPMATDSVRRLQSSTFLAGSPGGRLGSHRPLRWSEKLGAGFVHVRKASLHSPSCALVLKERCAGAATQGTGRVNMEDTYTIELDSTGKEPAFFGVYDGHGGSAVSEMLKTTVWPIYKKKLSDPDVVRATRAAYLEIDQLTLMQPKGLFGALRERGLGGSKCGATAATSVLIPKPDGSKVLVTANVGDARVILVRGGQAIQLTFDHKPDVKEERDRIEAKNPTPRKPLVQNVGGTWRVGGLLALSRAFGDVYLKDWTDNKQDGARGGFGLTAEPHISVETLTPDDQMIILGTDGLWELGNQEVVDICLAAGDSASPEDILKTLFKVAVEKGVTDDLAGIIIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ40</accession>
    <name>A0A8T0IQ40_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G043500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33984">
        <property type="entry name" value="OS02G0717600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33984:SF2">
        <property type="entry name" value="OS02G0717600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="472" mass="51406" checksum="016B4701E582ED11" modified="2022-10-12" version="1">MAGGGNSPVVAVKLTNSTQAESWTEGRLLGGDVVLQITSDTGVMLVAPFSGGKTGLMREVKKLYNAPGGIKIKVKRGSSIVEVRAKVAVDESSLLKKTYVLASATDSSHIATLVDAMEQDCLLLQDKSRKMLEATKMLRDFSKKDDLLVKLSSMKLKDSYVAYPWEQKMMTFLPVSGSAMVFSLLVMPPALSPKARDYAGVEQTSARAIAWLSAAQASGVPITFVNIQTEPLFMQFADYQVPGYKQDPAVIGNTGCYRLQDREAMDVDVVRAVRLWYSPAAAELAIDLKPEENESRLGVGISCTEEGFCHVSSVDPGTVADRAGLQTVYQAACAAGKLLVISRLGGEKITPWLVATSGSIRCYDTISMSNKLSLHRQTGQSIRLHVMVWEGALTANLYNSTEDISNRDKGIPSGYANRSAYGNSEDHSPYYSKSQEKQYMSKDLSDFDVVTNSHAEPSLAMSDSYLQYKYVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQQ5</accession>
    <name>A0A8T0IQQ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Outer envelope membrane protein 7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G263400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038944">
        <property type="entry name" value="OEP7-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33982:SF5">
        <property type="entry name" value="OUTER ENVELOPE MEMBRANE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33982">
        <property type="entry name" value="OUTER ENVELOPE MEMBRANE PROTEIN 7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="89" mass="9666" checksum="EA3E4AD05C12A006" modified="2022-10-12" version="1">MGKSPQRERNVWSTVLITAAALIAAWASIELAFKPFLTAGRASINRELDPDYDPDDELDDGAARPKSPNAEAKDAFESLKNQSSTSKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR99</accession>
    <name>A0A8T0IR99_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EVE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G076000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd21133">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052181">
        <property type="entry name" value="5hmC_binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002740">
        <property type="entry name" value="EVE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047197">
        <property type="entry name" value="THYN1-like_EVE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087:SF8">
        <property type="entry name" value="OS03G0676100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14087">
        <property type="entry name" value="THYMOCYTE NUCLEAR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01878">
        <property type="entry name" value="EVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EVE" evidence="4">
        <location>
            <begin position="109"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="262"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="364" mass="39555" checksum="25BB259625450FFF" modified="2022-10-12" version="1">MLHPHLVEILSYHYASHVLSCRAAHSFGASCKSDGGKVMLRNESMPSLLHRSSSIVGSLTARNRHLTSSLSCLGFSHGGVLRTRSVSAVVVVKAGSQGKGGGGGIRMGYWLLKTEPGEWGWEHQERNGGVSHWDGVRNAQAQGNLRSMRMGDHAFFYHSGKGPCVVGVVEVVRAAYPDSSDESGKHCMVDVRALAAFPSAVPLSVIKGDEAMRDWILLRQSRLSVMPVSPAVWARVCELGELSPPLCVTAGDDDAAVAEVKPTEPKRTAKEKKQKASVRDSSEVEEEPKKRARRLPAKARNGVSTDIQEDVKQEVHSTEFGVVSVAELKTYQRVSRRKVGIVEVAVVEAKVSKRQKPRGVNKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITC1</accession>
    <name>A0A8T0ITC1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G083500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050715">
        <property type="entry name" value="LRR-SigEffector_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058546">
        <property type="entry name" value="RPS4B/Roq1-like_LRR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752:SF187">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23286">
        <property type="entry name" value="LRR_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="26"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1064" mass="119430" checksum="254A31B16B86B946" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITM8</accession>
    <name>A0A8T0ITM8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G068200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="DUF676" evidence="4">
        <location>
            <begin position="25"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="NB-ARC" evidence="3">
        <location>
            <begin position="307"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance protein Roq1-like winged-helix" evidence="5">
        <location>
            <begin position="583"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="753"/>
            <end position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0586146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="983" mass="109596" checksum="D7AF9BEFB7E39A8B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXI7</accession>
    <name>A0A8T0IXI7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G244700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9606" checksum="80ADFD6A804ACFC3" modified="2022-10-12" version="1">MDNESQCAVVMLYRLQVISFGHPNLTCEHGCRISYVARMRDSNIWHRCVSTNPVCICHYSKILLRSFLQFTGADIAAMSIHAGNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXV0</accession>
    <name>A0A8T0IXV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plant heme peroxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G187200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000302">
        <property type="term" value="P:response to reactive oxygen species"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1620:FF:000001">
        <property type="entry name" value="Thylakoid lumenal 29 kDa protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044831">
        <property type="entry name" value="Ccp1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002207">
        <property type="entry name" value="Peroxidase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356:SF34">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31356">
        <property type="entry name" value="THYLAKOID LUMENAL 29 KDA PROTEIN, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00459">
        <property type="entry name" value="ASPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="3">
        <location>
            <begin position="162"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0587729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="408" mass="43851" checksum="553BD826C20C6A4C" modified="2022-10-12" version="1">MTSPHRHCTQSPVPANRHHPATQALSIIPPSHPPSSNAALAPGIRINSRISLLSLVDWSLMAMAVGVSWTLCAPALRISSSLLTVGGNAGANSMPGIRSKVGVRCQASEKDDVIVTRRDVFVGVAASTVAAGVWTSFPGSQEAQAADLIQRQQRGIFLTSLKNKLREEIAANPEIIPDLLRLALNDALTYDKESKTGGANGSVRAELSRPENEGLEKAINFLENIKNSTDDAAVTKGGPISWADLIHIAAQSAVKRTFIQSAVRKCGGDQKKGEQLYTAYGSTGQWSQFDKLLGRAGASEADPEGRVPVWGTASTTEIKERFAKLGIKPRQIAVLSAFLGPDQAATEAKLAADPEFAPWVKKYIDSRETISQTDYEVDLITAFTKLSVLGQTINYEAYSFKPKGTIRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZC4</accession>
    <name>A0A8T0IZC4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FG-GAP repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G207800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="278" mass="31058" checksum="8BA7EEC4311F076A" modified="2022-10-12" version="1">MALYQRRVLATGTVFDPEENGVWTFADINGDGSQDLVYIKTRNTGPGRRVEVHAAKSYESRFQEYFFGQITVFGVENNGTWLMQDYTGDGKADLVYIKTRNTGTNMVEVHVADAASRYQSYVLQTGTCFNCEDNGAWTMSSKGDLVFIKTRNTGSGKIEYHVASKSSNYQQFTQHVATDFAAEENGTWRLAPICSGDFADLYYIKTRNTGTGMVEVHAVSAASGWKSRIIATGTSFNLEENGQWLMAHLTRQTQPDLVYIKTRNCGSDKIEVHVTPRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0N8</accession>
    <name>A0A8T0J0N8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G251000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0N8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF11">
        <property type="entry name" value="OS04G0670900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="315"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="281"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="162"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="611" mass="67666" checksum="FE5F994691CF7DD9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2S6</accession>
    <name>A0A8T0J2S6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G082500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2S6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="13129" checksum="1CB80DCB4E3A3DD0" modified="2022-10-12" version="1">MELVNKCWRLQLFDSLGGHYPTLALPGYWIFSRTWKISSTEAIALWFLELLRVSTSSSYPLKLKHILLQGPKLGIHQFLIWLCYTVFKYLTLFWLLLIQPYMSRMKVSESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J553</accession>
    <name>A0A8T0J553_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G059300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J553"/>
    <dbReference type="OrthoDB" id="199711at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="194" mass="21575" checksum="A8D1E48DF47D8C8B" modified="2022-10-12" version="1">MWGCSSGESGKFIAEGRERIGSMAMWSRAVIVALLSCALLFPSLLMAAEEDQPKDFEYFQIWVSQDGETHIAECKMKGFNYTAYSSLPQYLRSDFGGEPVKFVLTELPVGLAQPLHNTPIVQFVATLSGSWYIETTDGTRRNLKKGQLLFQDNTANSPADKSPQHYSGTHGDKPCHQLIIQLSRPPQVDNPCPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J555</accession>
    <name>A0A8T0J555_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G117400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J555"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044239">
        <property type="entry name" value="FKBP20-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47414">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP20-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47414:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP20-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="195"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0590665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="298" mass="33405" checksum="8237146A2D4DB5BA" modified="2022-10-12" version="1">MSLQLCRVWLHPNHVLCCNAASAWSLRSAPKGFAEAPSLATRTTCAKVRCMHSDTADESRESSSGLKTEHRFRSEAPPSNGLDDSKFTTCRTSRRRDFVNLAIGLGSALLVGRWAEKGTAIAVTKKDTRSPYDEKKLLDQNRRMQKVNNAPEDFPNFIREGFEVKVVTDEKYTTAQSGLIYYDLVEGQGELPKDGQQVKFHYIGYNENGRRIDSSYQQGEPARTRLGIKGMIPGFEEGIRTMKPGGKRRIVIPPELGPPVGPSTFFSAKQFEVFDVELLEVKDCVRRTVFLYSDVVCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J651</accession>
    <name>A0A8T0J651_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Lon protease homolog, mitochondrial</fullName>
            <ecNumber evidence="10">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_1G142800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer or homoheptamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10 11 12">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="10"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J651"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051131">
        <property type="term" value="P:chaperone-mediated protein complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070407">
        <property type="term" value="P:oxidation-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd19500">
        <property type="entry name" value="RecA-like_Lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000021">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000080">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.5270:FF:000001">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000002">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000015">
        <property type="entry name" value="Lon protease homolog, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.5270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03120">
        <property type="entry name" value="lonm_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054594">
        <property type="entry name" value="Lon_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027503">
        <property type="entry name" value="Lonm_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718">
        <property type="entry name" value="LON PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43718:SF2">
        <property type="entry name" value="LON PROTEASE HOMOLOG, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22667">
        <property type="entry name" value="Lon_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00830">
        <property type="entry name" value="ENDOLAPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 10 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 10 11" id="KW-0645">Protease</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="15">
        <location>
            <begin position="158"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="14">
        <location>
            <begin position="825"/>
            <end position="1009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="67"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="764"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="79"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="915"/>
        </location>
    </feature>
    <feature type="active site" evidence="10 11">
        <location>
            <position position="958"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="532"/>
            <end position="539"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0591015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1032" mass="113127" checksum="4EA58D7466C3D732" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6K2</accession>
    <name>A0A8T0J6K2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G099100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6K2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035927619" evidence="1">
        <location>
            <begin position="23"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16775" checksum="BB3DB3FF84D23D70" modified="2022-10-12" version="1">MRDLQARVVVLVLLIMRPLTGSANFHVVNMYYGFNNDVGFDYQMVIPSTKWGCEGIPRETIAGGRYPDCHGGYDLHVPGNTCNYSGVIIRPACHGIYFGKLFDKDGEDIGNCYWHDAGEISAFACKLNLSNSNYQIVYDRLLCSTKMCGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB88</accession>
    <name>A0A8T0JB88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G224800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12290" checksum="9998CDB2C39F3730" modified="2022-10-12" version="1">MLIGPREGRSKKWDMQMYVPSARYSLVKGERIVRSVQSTLLCGIQKGVAGLCTRHGCSPTGIAYGTYIFMRHIKLGPQTRSLNVTTCSWRPRSFSSACVKVALNKSIPEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDK5</accession>
    <name>A0A8T0JDK5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G307700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDK5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9690" checksum="1795C24C90067268" modified="2022-10-12" version="1">MPINSNSVNNNGLPTTICRKVITRVTGFLNEVILRTREPPRFICPAAAATRTLLATSMNSSVSSTISSCITPQNSSQELANLSEDIILLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JE40</accession>
    <name>A0A8T0JE40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Sm protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G292300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the snRNP SmB/SmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JE40"/>
    <dbReference type="OrthoDB" id="2020720at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005686">
        <property type="term" value="C:U2 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071004">
        <property type="term" value="C:U2-type prespliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005687">
        <property type="term" value="C:U4 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070990">
        <property type="term" value="F:snRNP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01717">
        <property type="entry name" value="Sm_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.100:FF:000004">
        <property type="entry name" value="Small nuclear ribonucleoprotein-associated proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047575">
        <property type="entry name" value="Sm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="Sm_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050914">
        <property type="entry name" value="snRNP_SmB/NAA38-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701:SF0">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10701">
        <property type="entry name" value="SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52002">
        <property type="entry name" value="SM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Sm" evidence="12">
        <location>
            <begin position="4"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="83"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="111"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="236"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="250"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS52002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0592941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="31465" checksum="954A3FC204FF59B8" modified="2022-10-12" version="1">MSMSKTSKLLLYINWRMRVTIQDGRQLVGKFMAFDRHMNLVLGDCEELRRVPPKKGKTQEEREERRTLGLLLLRGEEVISMTVEGPPPPDESRAKAAAAAAGGPGIGRAAGRGIPTAPANQAQPGLAGPARGVGGPAPGMMQPRPQVSAGPITYTPPPGPIPGVRPPGPPPPGQYAPRPMPGPPGAPPPGMRPPQMMQGPPGQGPPQGYGQGPPGRPMPPPPGPPPQMSGPGMPGPYGQRPMGPPQMMRGPPPGMGGPGGPPRPGMPPQMQGPPRPGMPPPPGAPPGMYGGPRPGMPPPQQQPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JFA5</accession>
    <name>A0A8T0JFA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G339600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JFA5"/>
    <dbReference type="OrthoDB" id="2414662at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033853">
        <property type="term" value="F:aspartate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033854">
        <property type="term" value="F:glutamate-prephenate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004069">
        <property type="term" value="F:L-aspartate:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009095">
        <property type="term" value="P:aromatic amino acid family biosynthetic process, prephenate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000033">
        <property type="entry name" value="Aspartate aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050596">
        <property type="entry name" value="AspAT/PAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46383:SF1">
        <property type="entry name" value="ASPARTATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="6">
        <location>
            <begin position="119"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0593568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="498" mass="53026" checksum="D3EDFDC86AEE6664" modified="2022-10-12" version="1">MTTCKSQLAKGTAIASSCPLPSIKDRTRLSQGALSPAWFIGNNSEQWHSSAYNLFAGSRREQSNLQQSTAMTAFASSNGANGASTTVDTTISPRVAALKPSKTMAIADAATSLVESGVPVIRLAAGEPDFDTPKSIVEAGTRAIQEGFTRYTPNAGTLELRKAICHKLQEENGLSYKPDEILVSNGAKQSIMQAVLAVCSPGDEVIVPAPFWVSYPEMARLADATPVIVQTSVSENFILKPEALSAVLTEKSRVLILCTPSNPTGSVHSLEDLKAIAAVVAKHPRLLVISDEIYEHIIYSPAKHHSFAALPGMWERTLTVNGFSKAFAMTGWRLGYLAAPKHFLVACNRIQSQSTSGASSISQKAGVAALALGNAGGEDVATMVKAFRERRDFLVQRLQAIDGVILACPEGAFYLFPDFSAHFGSHAEGFGTISDAETLCRFFLEKAKVALVPGDAFGNGGCIRISYAASMEELQTAMESIESVMSLLKPATAASFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4H0</accession>
    <name>A0A8T0G4H0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G070500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4H0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd19101">
        <property type="entry name" value="AKR_unchar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147:SF2">
        <property type="entry name" value="NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43147">
        <property type="entry name" value="PROTEIN TAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="1">
        <location>
            <begin position="75"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="398" mass="44713" checksum="780EB98D4E552BC0" modified="2022-10-12" version="1">MASFTLSRHHVASSVAVLSGAKLVHRSAASLRSRVRATGRRLLTTVAAEADTAAEQRADRAVVSSGDDRLEICRVINGMWQTSGGWGRIDNEDAVDAMLRYVDAGFSTFDMADHYGPAEDLYGLFINRVRRERGDELALQVRGLTKWVPPPVKMTRAYVESNIDRSRKRMDVKTLDMLQFHWWDYADNGYLDALKHLTDLKEEGKIKTLALTNFDTKRLQIILENQIPIVSNQVQHSLVDMRPQTHMADLCNVMGVKLITYGTVMGGLISEKFLDANISIPFAGPALDTPSLNKYKRMVDAWGGWNLFQELLREVKKVANKHGVSMSTVAVRYILDQPAVAGSMIGVRLGLKEHIKDSQAIFRLQLDEDDYERIASVTKRGRDLQDMIGDCGDEYRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7U3</accession>
    <name>A0A8T0G7U3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Fibronectin type III-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G098500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7U3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046556">
        <property type="term" value="F:alpha-L-arabinofuranosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031222">
        <property type="term" value="P:arabinan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1700:FF:000001">
        <property type="entry name" value="probable beta-D-xylosidase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.300:FF:000004">
        <property type="entry name" value="probable beta-D-xylosidase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="entry name" value="Glycoside hydrolase family 3 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="entry name" value="Glycoside hydrolase, family 3, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721:SF3">
        <property type="entry name" value="BETA-D-XYLOSIDASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="SUGAR HYDROLASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="Beta-D-glucan exohydrolase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035750112" description="Fibronectin type III-like domain-containing protein" evidence="8">
        <location>
            <begin position="28"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type III-like" evidence="9">
        <location>
            <begin position="698"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="788" mass="84897" checksum="A9E61E0BA3B49181" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G815</accession>
    <name>A0A8T0G815_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">(S)-ureidoglycine aminohydrolase cupin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G134300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G815"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008579">
        <property type="entry name" value="UGlyAH_Cupin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33271">
        <property type="entry name" value="OS04G0445200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33271:SF7">
        <property type="entry name" value="PLASTID TRANSCRIPTIONALLY ACTIVE 18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05899">
        <property type="entry name" value="Cupin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="(S)-ureidoglycine aminohydrolase cupin" evidence="1">
        <location>
            <begin position="87"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="18974" checksum="64718B7F622BD396" modified="2022-10-12" version="1">MAMALSATALTPGLSARQPTLPTPKTSLKTSHCSLSATTAHLFAGKRGAGARRRGGAVVTCYARPLRPVEERFRIQVERNVDEARLKELAVQRWSKWESDVSAFDHEWKVDEQVYVVRGSVKVTPEDCQDSAYFYAGDLVRFPKWFCATLSFDGEYEQRYRFLAYGDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8G7</accession>
    <name>A0A8T0G8G7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G107000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8G7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11755" checksum="24A90362A76B6A45" modified="2022-10-12" version="1">MHAVGILRRDVKDSNVLLQGSDDGFQYSTLIDYECSVRVMGTGFWRAPEILEQLKKRVPSKDLVYTEKADVYSYGMMCYGLSTGRIPFEGHDFDAVLSGHDIMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA25</accession>
    <name>A0A8T0GA25_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transmembrane 9 superfamily member</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G179000</name>
        <name evidence="11" type="ORF">KC19_12G179100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA25"/>
    <dbReference type="OrthoDB" id="1666796at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072657">
        <property type="term" value="P:protein localization to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004240">
        <property type="entry name" value="EMP70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766:SF41">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10766">
        <property type="entry name" value="TRANSMEMBRANE 9 SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02990">
        <property type="entry name" value="EMP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0967">Endosome</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036511308" description="Transmembrane 9 superfamily member" evidence="9">
        <location>
            <begin position="22"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="322"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="357"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="479"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="547"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0555573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0555575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="587" mass="67247" checksum="8112D475FA10E32E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCP7</accession>
    <name>A0A8T0GCP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G004800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="45" mass="5563" checksum="3F01217B55E2A983" modified="2022-10-12" version="1">MPDFYAMEREDVGVYEDMTGWRSFWLVRWGRTKIVNPRLEILQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF79</accession>
    <name>A0A8T0GF79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G120300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6208" checksum="6440E8C3A3792FD6" modified="2022-10-12" version="1">MLVVLSTSNWRDIHYFNVSDNREYFGRFLTKLEQGRYCSGYSAVSDASACKALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFQ1</accession>
    <name>A0A8T0GFQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G160500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7390" checksum="ACA4FD0E1F3229DE" modified="2022-10-12" version="1">MFLTNLAPACIQVLGEVVENQEQPPKALRRPTGRRLTLIYEAWIRARRCPSNHLESKTSKPQSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG38</accession>
    <name>A0A8T0GG38_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chalcone synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G136100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030639">
        <property type="term" value="P:polyketide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000014">
        <property type="entry name" value="Chalcone synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.47.10:FF:000025">
        <property type="entry name" value="Chalcone synthase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018088">
        <property type="entry name" value="Chalcone/stilbene_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877:SF14">
        <property type="entry name" value="CHALCONE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="HYDROXYMETHYLGLUTARYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00441">
        <property type="entry name" value="CHALCONE_SYNTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Chalcone/stilbene synthase N-terminal" evidence="6">
        <location>
            <begin position="21"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone/stilbene synthase C-terminal" evidence="7">
        <location>
            <begin position="248"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="4">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000451-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="43491" checksum="9A30EF5C4C10B6FA" modified="2022-10-12" version="1">MAPSGEVQAPVMGTALPRGQPRAEGPACVLGIGTAVPPTEFLQSEYPDFFFNITNTSEKEALKAKFKRICDKSGIRKRHMFLTEEVLKANPGICTYMEPSLNVRHDIVVVQVPKLAAEAAQKAIKEWGGKKSEITHIVFATTSGVNMPGADHALAKLLGLKPSVKRVMMYQTGCFGGASVLRVAKDLAENNKGARVLAVASEVTAVTYRAPNENHLDGLVGSALFGDGAGVYVVGSDPKPDVEKPLFEVHWAGETILPESDGAIDGHLTEAGLIFHLMKDVPGLISKNIEKFLTEARKCAGSPDWNDMFWAVHPGGPAILDQVEAKLKLSKDKMQGSRDILSEFGNMSSSSVLFVLDQIRQRSVKMGSSTLGEGSDFGFFIGFGPGLTLEVLVLRAAPNTSTIAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHH7</accession>
    <name>A0A8T0GHH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G031900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14661" checksum="F1F8C16C3B07C3EE" modified="2022-10-12" version="1">MSKRKFFARALLNDNQHCRKYEVVRTYIHSILLDTLSSCNDKLPYLSLTTSPLLQMFRQGLLKCYCNSVYSVELMAGKEFPHSNPSSSCEQLKSIILLMPGHPKDCISSQEHFSAGMKGHDICAHLTHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHP2</accession>
    <name>A0A8T0GHP2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Late embryogenesis abundant protein LEA-2 subgroup domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G036100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHP2"/>
    <dbReference type="OrthoDB" id="1929523at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055301">
        <property type="entry name" value="Lea14-like_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31852">
        <property type="entry name" value="LATE EMBRYOGENESIS ABUNDANT (LEA) HYDROXYPROLINE-RICH GLYCOPROTEIN FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117070">
        <property type="entry name" value="LEA14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="206" mass="22489" checksum="7607818B5278B07C" modified="2022-10-12" version="1">MSTMGFPRPGDSVPIKITEYEGKTRRRKMICVVIMGVIVVITIVLVILGLTVFKARDPKVQINTISLETFSIEANSLNMSLVLDVTVHNPNREGFRHSECLTRLFYYGDPVGQATIPAGNIKSKGNECFSVRLAVEAGHRVLVNQNLPGNIVSGRLPMVATTTVAGVIKVLGVFKHHAVTTSHCDVSIFVSNATIQSFVCRHGMKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHS1</accession>
    <name>A0A8T0GHS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase S9 prolyl oligopeptidase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G064000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHS1"/>
    <dbReference type="OrthoDB" id="10249433at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008474">
        <property type="term" value="F:palmitoyl-(protein) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000298">
        <property type="entry name" value="Bem46-like serine peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277">
        <property type="entry name" value="ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12277:SF81">
        <property type="entry name" value="PROTEIN ABHD13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S9 prolyl oligopeptidase catalytic" evidence="2">
        <location>
            <begin position="137"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="309" mass="34316" checksum="60889C2FE2BCF712" modified="2022-10-12" version="1">MGGWWTWLNGLLYGMGGLACASVAMLVAFQEKLVYVPVIPGMKRGYPIVPSRLHLRYEDVWLTAKDGVRLHSWYIEAHANCPGPTILFFQENAGNIAHRLQFVELMVRRLQCNVFMLSYRGYGDSEGFPSQHGLKLDAQAALDYLHGRQSVDSSRIVVFGRSLGGAVGASLVRENPGKVAGLILENTFTSVLDMAGVMLPGLRYIVGGKGGLLNWFVKSPWKTIELIKHIEAPILFLAGQLDEMVPPAHMHQLYEAAQETSSAQHTFVEFPDGMHMDTWMQGGERYWRSIEIFLQNNASGGRSSSQSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI70</accession>
    <name>A0A8T0GI70_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G014500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050231">
        <property type="entry name" value="Iron_ascorbate_oxido_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47990">
        <property type="entry name" value="2-OXOGLUTARATE (2OG) AND FE(II)-DEPENDENT OXYGENASE SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00682">
        <property type="entry name" value="IPNSYNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0408">Iron</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="4">
        <location>
            <begin position="211"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="41169" checksum="6FABCF8EFBBD1572" modified="2022-10-12" version="1">MLAGDGDGESASGPLFTMQAYFEGHMKMKDFARTGKERPTIPHDVFGQTLPVVDIAAIREGSVEERQANVATMLEAAKSWGFFRIANHGIPLEVVKQVEADGKEFFALPMERKMRVRSSDVVNFFGYTAGSPIKWKSKWWLEGLQLKVTENGLDDLVAQAYPDEPDHAARFKKDLTAFFTPVHELSRFLVEELTEALGLTRDTFTRHEVTQMNSTGRMNHYPVCSDPDSVLGIPAHGDIQMTSILYQDGAGGLQVLKDDGQWVGIRPEESTLVVNIGDTFMALTNGILRSAVHRAVLNSKKDRYSTVYFYGIDNTTTLTVPPELVTEEHPLKYRPFTVQEHRKYLMENEIPLHGPRHLQIDPDDATS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJL4</accession>
    <name>A0A8T0GJL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G123000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035727790" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="9621" checksum="559C3E17CBAD68EC" modified="2022-10-12" version="1">MIGVILPSLGLVLAMSSPEAANAGLGVPGRVRSFSRIISLTPLSSDSLSLLEYCILFLPRDLFRFLPLGIVILSNGRNTHLCETASSHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJP9</accession>
    <name>A0A8T0GJP9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G025400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="114"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="50253" checksum="34AAB0D5225767D0" modified="2022-10-12" version="1">MRNMGSSSGDEDGGSGAVVAPEAYSGVRDDVYYTAVASTSSGVEGSEYLTAAMSEQQISSLIETSREQGTWSELKHDGPRHDGSSTLAHSDAAIWEELKRSHPRVFQDFHKGWLQLGQVIAEGSQATIYQAKMHWENKHSSDQLVVKVFKMEGFSLADLQRQWPQATKTPPQSTDETLNCKFNHFKLGGVVFGEALTHCNLIHYGTFSKDGRFAFVMPRYWGDLRSLINLKVKEEDLRIKLVLENSQSFIPTSRLRFPPFSHAKASRIMLDIAKGMKALHDRGVLHRDLKAANVLIQNNPLVDDDWWYCNVADYESSMQVQGTGFWRAPEVLKELLKKACDRDEGIWTEKVDIYSYAMTCYEVLTGLIPFVGFVKSDWERVFNGERPHFPDFVDPSLKGLVEKCWDVEPHNRPEFDTIVEELKLLVEEEEDEEDLPPFMKYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKT9</accession>
    <name>A0A8T0GKT9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G149000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="14644" checksum="428D66FB5AD60D9A" modified="2022-10-12" version="1">MLKRNMYTEVEISRTQNRHDATVFGSVWVLCTIWSLDCQATHFVAAIQRSGAQSAGRDRFVLMVSACERVIDRDPLRIGGRETGRAAPTRPDLTRPDPESGSGACTSVEVVEISNPYFLFRLAVVIGLNVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPI3</accession>
    <name>A0A8T0GPI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Non-haem dioxygenase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G184400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48420:SF1">
        <property type="entry name" value="NON-HAEM DIOXYGENASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="398" mass="44458" checksum="31D50B49587346D4" modified="2022-10-12" version="1">MEGLEDGGDLQQIRTTPPPVGRVITIPYADLLREDLDLSRELEAGFGLNSLGIVAISGVPKYSELRSRLLPLASRIAALSEESKKSLEDPASRFSFGWSHGKEMLKSGQPDIYKGSFYANPVVDVPTTEEILIERYPSYCRPNLWPREDLPELEPAFKELGHLILDVGLLLAHHCDKFVSARKSDYEQGKLVRMLQSSKCHKGRLLHYFPASSRDAEEREKEMASWCGWHFDHGSLTGLTCAMYMREVARVPNPDPQSGLYIRDRLGSIVKAVFAEEDIAYQMGEATEIHSGGLFRATLHCVQAACGETAVGVDRNTFALFMQPQWDEPLISPDSTEVIACALESLELSSALCSLNSSCLMMLTGFICIVPAVTEVCQLWRFYRGTSQQVLWRFMNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPY1</accession>
    <name>A0A8T0GPY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiamine pyrophosphate enzyme TPP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G167600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPY1"/>
    <dbReference type="OrthoDB" id="3633556at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005948">
        <property type="term" value="C:acetolactate synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme_TPP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968:SF129">
        <property type="entry name" value="ACETOLACTATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="THIAMINE PYROPHOSPHATE ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Thiamine pyrophosphate enzyme TPP-binding" evidence="3">
        <location>
            <begin position="44"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="243" mass="26709" checksum="003FB692B110823C" modified="2022-10-12" version="1">MEVKKDLDAHLLKGAKEPCFPLVPQRIIADLRKQVPHDGIVCLDNGMYKIWFARCYKAYEPNTLLLDNALASMGAGLPSAMAAALLHPEKKVVAVCGDGGFMMNSQELETAIRLKLNLTILVLNDNGYGMIKWKQNLAGFDKFGLNLGNPNFAEYANSYGIKSYLVTNADEFTYILHECLFHLTEGIKLVEVPVDYTWANEILDHELPGMFKQRKSEPAAGTEISKALASSAPVALSCSLGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRN0</accession>
    <name>A0A8T0GRN0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G119100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035865192" evidence="1">
        <location>
            <begin position="19"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6481" checksum="776E310579B94653" modified="2022-10-12" version="1">MNIFIYVGLFVFTETCYSLSPASIVELSQKFQFEDVDVLTIRHIFSSTAMCLPYYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRP1</accession>
    <name>A0A8T0GRP1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G120000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11764" checksum="FE38399E8AB21404" modified="2022-10-12" version="1">MFGSLEVLPDAIAGELRSGAIWLEKRQVQDVSNTIWKQERHCNPPTNTYLSCSSCDISCNSFYMFCKNSGSLAKLALNFSWSAAAFLYTVSAFFLVLFVSSFPSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRR0</accession>
    <name>A0A8T0GRR0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G030200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11759" checksum="59732F9E35834608" modified="2022-10-12" version="1">MQFVNPRTQASQGKLAAGPLQDSAPQHENSGALLDYPDNHLDWQDEEQTNDDHSKFDWTKRCASACMRASSRNEKQMPQLSSQAPHSEACMGHWGSPSARPKEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSC8</accession>
    <name>A0A8T0GSC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G157400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="200" mass="22416" checksum="54A4A6142A7D5BAE" modified="2022-10-12" version="1">MTEEKGTVLLIGKSRSGRTTLANMLVSGELKDGPLAPSDTNNYFCETYAGRGWTVVDTMGFGEPLGGIVPEEYARKMVIDFLNEVKAPYSHIMLVVDISNIQTLERGRRSCILIIWKIFLEIFEGGEENFVVCGNNLESIAPARIEETFPECKCFLYVNFFETTAIEMNGSIAEWRQKELARIEEEMSAMFKTLSGADTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUV1</accession>
    <name>A0A8T0GUV1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G170900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="19652" checksum="46EF98941D22FA0A" modified="2022-10-12" version="1" fragment="single">MITERKLFSYQLKKGAPRKSWWKRLQRRNQAINLLSSQPGRSRSNRVKLLPNRGLPCQFPVLNNATEAPSRTREGTSNVSSKKTPGMHRDVGRPQQEGILNLSFPTTSLTKSTLKQTSQKLKLKPDHKPHEQNSSQLPHNLLHHQPTQTPFQKLQKHKKKKQHLTPTRPAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWN2</accession>
    <name>A0A8T0GWN2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G056100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWN2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16097" checksum="6727F7EBBE052C1D" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMLSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYB1</accession>
    <name>A0A8T0GYB1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G005000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYB1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10628" checksum="6C20179AD866BBA4" modified="2022-10-12" version="1">MSWELASTASKHGTPDANIARERMKNDALTHSLTRLSAVTSLGKWSRLNSLTHSLTHSLVEGEGEGEYNLCNVSKSPCCRVLLTLPSRLTPAVDPGVGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZJ8</accession>
    <name>A0A8T0GZJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC1 atypical kinase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G039900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF119">
        <property type="entry name" value="OS04G0640500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC1 atypical kinase-like" evidence="2">
        <location>
            <begin position="15"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8810" checksum="620952A6B1B64BFD" modified="2022-10-12" version="1">MIELNATVTRPCSKIQEMDYQAEARNGIRFRKLFGTLPDVLVPEMYSELTSHRVLVMEWVEGQRLSEVNDLRLVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0X7</accession>
    <name>A0A8T0H0X7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G170200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0X7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16402" checksum="6A1F878ABF3F0A7A" modified="2022-10-12" version="1">MAQREIVFVNGSNVRLKFSYRYGLTASKIQYLQTLAPNESFTYKVRDDGTYEKIEVDYQISSEGSGYFKPTNLKINADTMSKYSKITVADCGHSGDVGTARMFRLETEDRPPTPGASEIVSGIARGIADSVGSVGARLFGNGASAGQDIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H340</accession>
    <name>A0A8T0H340_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G001300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H340"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035897140" evidence="1">
        <location>
            <begin position="22"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="6244" checksum="9CE38FE38864A3D9" modified="2022-10-12" version="1">MNMFLFFGPEWMLLFINVCSSDEMMDRIWLHYASAIHSPESCACWWMCMPSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H368</accession>
    <name>A0A8T0H368_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G171200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H368"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8204" checksum="5512756A9965C0A0" modified="2022-10-12" version="1">MRGCWTWSSSVRWRKKNVVLITYCLLQMRKSGFAVKDGLHQVQGCRVVFLNIPEAQSMKKPGGRRLSAPPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3G8</accession>
    <name>A0A8T0H3G8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G182100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3G8"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17581">
        <property type="entry name" value="REC_typeA_ARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045279">
        <property type="entry name" value="ARR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874:SF147">
        <property type="entry name" value="TYPE-A RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="118"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="244"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="292" mass="32033" checksum="73434F7D8A59C2DF" modified="2022-10-12" version="1">MVRKSSEEEERCESAVLHLACQDPNCRDASEIAGLVKLQDMGLNTSKKNRKVNSVAVTATPPPRSHNSFEDSVHRKVVGETTAETMSLLSASVENYCPDNSDLVGSKQVPSVSSFQYHVLAVDDSRIDQRVIEKLLKTSSYKVTTVNSALRALEVLGLSDSAPSPFKKLDINLIMTDYCMPEMTGYDLLKRVKAKTSALKEIPVVVMSSENDSNRIKRCLAEGAEEFIIKPVKMSDVKRLRGHIRCPSTTSSSGTGESSGSTCGKRKLDASDDLHEVSSPERRPRLSELLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3L6</accession>
    <name>A0A8T0H3L6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="6">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G068200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF36">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE IV SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11523">
        <property type="entry name" value="DUF3223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="8">
        <location>
            <begin position="377"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="209"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="457"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1556"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2165"/>
            <end position="2197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="467"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1664"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1760"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1907"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1937"/>
            <end position="1950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="2002"/>
            <end position="2031"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2219" mass="242938" checksum="8884EF2E9206FAB7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3T5</accession>
    <name>A0A8T0H3T5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G027900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of the proteasome complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3T5"/>
    <dbReference type="OrthoDB" id="268428at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005839">
        <property type="term" value="C:proteasome core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03758">
        <property type="entry name" value="proteasome_beta_type_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000008">
        <property type="entry name" value="Proteasome subunit beta type-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035206">
        <property type="entry name" value="Proteasome_beta2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF2">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA TYPE-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="205" mass="22898" checksum="1EB3AB27777DFEE6" modified="2022-10-12" version="1">MECLFGFEGNGFVVVVADTSANQSIVVQKTTEDKITCLDSHKLLGCIGESGDRVQFSNFIQKNLNLYQFRNGIPLTTLAAASFTRCELATALRKAPYQVNIMMAGFDKRTGPSLYYLDYIATLQKLEKGALGFGAYFILSIMDKYYKKNMNLEQALQLVDKCIWEVGTRMVASPAGYIIKIVDKDGARLLERRGRPAEEHGDPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4A8</accession>
    <name>A0A8T0H4A8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G092800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009976">
        <property type="term" value="F:tocopherol cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025893">
        <property type="entry name" value="Tocopherol_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35309:SF4">
        <property type="entry name" value="TOCOPHEROL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14249">
        <property type="entry name" value="Tocopherol_cycl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="468" mass="52256" checksum="E8F5238DCB863EB3" modified="2022-10-12" version="1">MLSFLERNLDPRNWWDEAAGQKKDEVLEGAREDFVREGDVGGLNGGSSCETVEMEKVRGENGASGGEMRWSEQDDDDWVKVPSMLPDGLGMFAQGHPMDPHEPNFSELLPEVLRPYPAFEGWFIRIWDSTKEFSAAVIMATNYATDESQVTILFAPGRDVNPEGDREAVKCGFTYAVAVKTKDAKFTRNRNAQECGERNVEPEGFRWEANGIGSIVVTPHVTEFDFTVEGYHFKARLTKEVLWDSHNSENGPEGWARYVSIIPCHWYVYSLGSTVDYSFSNPEKTIFSEGSAIGHVEKNWGLSFPAGHVWLQAFSSDNTSQVCCAGAYFNTSIEKLSSPYIFVLGYRSPKLQLDFRTNDLGIVFKDINFSPLASCFSITAVGPSHTVELKAYAPYDTFSDPVLAPVTKREWKPACRESYLATVEMKVYEHLAWGIPGTENLVDTQVLKSAALEFGEDLLTEASECTGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5F8</accession>
    <name>A0A8T0H5F8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G024200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5F8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008373">
        <property type="term" value="F:sialyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd19952">
        <property type="entry name" value="GT29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1480.20">
        <property type="entry name" value="Glycosyl transferase family 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001675">
        <property type="entry name" value="Glyco_trans_29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038578">
        <property type="entry name" value="GT29-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46779">
        <property type="entry name" value="BETA-1,6-GALACTOSYLTRANSFERASE GALT29A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46779:SF1">
        <property type="entry name" value="BETA-1,6-GALACTOSYLTRANSFERASE GALT29A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00777">
        <property type="entry name" value="Glyco_transf_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0565927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="496" mass="56300" checksum="FA0C84EF98668620" modified="2022-10-12" version="1">MGRPVTYIKCMADVRYGRLHWARRLRFWESGVSGHVVDLSRHVVQLQLESWSCTIVAIAMPKVMIGYDHLPCIYLGMAFQWRDSLKWINMGESSVKYFRLRVHHLLTVVVLALVSIAALFTDITTTSRLPGPEDGRFKPLGPARLSRPWHGRMVNESEFMAFVESEDDAEHEKDLIKEVLQGNQLDPRGGHRGRAARRPSRLPSPHYAPFWPEFRAMLRARVDMKRYDPKVMQSLVATIKVPIERHRQKALKPGLRRAAQRRYASCAVVGNSGILLNSTYGEAIDAHEAVVRLNNARAKGFETHVGRKTTIAFMNSNILHKCARRVRCYCQAYGGDDGDNDDVAIVMYVSQVQHLMDVAMCRPAHAAPLLVTDPRFDALTARIAKWYSVREFVECTGKGVSEWPWVGGFHYSSGMQAVMLALGICEEVDLYGFGKANGTKHHYHTAQPQELHIHDYAAEYIFYDELAVPSSQEAIPFLRDAGIRHPRVRVFGHEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6M2</accession>
    <name>A0A8T0H6M2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_7G147700</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6M2"/>
    <dbReference type="OrthoDB" id="40902at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05117">
        <property type="entry name" value="STKc_CAMK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000015">
        <property type="entry name" value="Calcium-dependent protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000004">
        <property type="entry name" value="Calcium-dependent protein kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000249">
        <property type="entry name" value="Calcium-dependent protein kinase SK5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="111"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="412"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="448"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="484"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="518"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="23"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0567606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="575" mass="63539" checksum="09198E43CEF7228C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9B8</accession>
    <name>A0A8T0H9B8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G124500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9B8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="12526" checksum="9138AE675B86BB66" modified="2022-10-12" version="1">MSFFSDPLDCQVPSARSSNQSMVSFHSSTRLSIPSPDTAPNLRSLTDTFAFTVNTCSSLLPSCGVGSNLSMAIDESFILAFPNILKSSEVDPVTTTIASGLQSCRLNRKLLGYQSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9D1</accession>
    <name>A0A8T0H9D1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G165800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9D1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="12689" checksum="7D002318A64C2E85" modified="2022-10-12" version="1">MPPPSHPHPSSKSHLISSHLISSPLLSSPLLSSPPKQIHITPMTPPHIMTYPPHTDISPHTLNSINNIPTNPHNNCLQIHPLSPTPLKIANVHSNNKLQGHRQQTTEKKPPQRVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB92</accession>
    <name>A0A8T0HB92_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G147500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB92"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="10042" checksum="88BC821B4DDF7CB0" modified="2022-10-12" version="1">MSITPSLNINPERKRCRIWQRCAINWVNIRFRFLSHQIRKSFKKTEGCYKDFGQFLTYRQSAVQAKPRAKAEDASWAARHCCHGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBU3</accession>
    <name>A0A8T0HBU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAT C-terminal dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G052000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBU3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="24276" checksum="51F859CB0CD79AC2" modified="2022-10-12" version="1">MDPPLLVLNSNNLADIADALIAELDTRFPANHVMDSLGIVFPQYWLQENVDSSFSAHLSILKDFFGTPKPCVNVEGDGDWVTQLLSSADLDSQMAMFKMAMKSNSKGVLTPPFTVNPMTKLWQILGSNALLVHAFPEYFKVARMAMTIVLGSMEDERAFSTVGFIKGKLRNKLSEHLPLCVQMFTQKFYTLKNFPYTEAVQAWRANKHRYCMNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCN4</accession>
    <name>A0A8T0HCN4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G060700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035731696" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="6080" checksum="FB63EF147AED1B7F" modified="2022-10-12" version="1">MNPLQVLQACMLLHALTFSCRIDLRELVHNYAVFCILESICVRSNRPLQQDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCS9</accession>
    <name>A0A8T0HCS9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G187100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11495" checksum="364B32AE4AAE876F" modified="2022-10-12" version="1">MPCHRAERTENATLALPRSLARSSPCLQGRPNFHTSRASRGLLPHHALRRAPQPPRHCAPGIRPACPLPHLRSFRRHSQTLQTQGPRPAAPPPHSDGCHNPVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKJ5</accession>
    <name>A0A8T0HKJ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G225600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035922282" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5608" checksum="9EC9FE6A7039A1B7" modified="2022-10-12" version="1">MNNFCTICSLTPGPSVLLVLLAMLNLSRSPTHLNCDLNSFTERIETQVLDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSW5</accession>
    <name>A0A8T0HSW5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG229300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48258">
        <property type="entry name" value="DUF4218 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="39691" checksum="CFDF23AB2BDA662B" modified="2022-10-12" version="1">MASGYMIEESLGFCTEYFSLYTHTRRRVWDAEEEMRDAGEVLLGRGVPRRLSYEQTLHVHDYVLKHSVPTAELLSEWHKQREAFKNSWVRYRSTLRGRSGPFPDHLIEPLPKFSSWINNHVRILRDEGFPVSRELESLHCMPSEYVTSYQAMWAYGAHYVVSNKEGLGYVSFDSGIAAIPPGSDTNEIDVGILRDIILVSYSEVNCVILEGSWIKTMDEGRRVIKKDQYGFWTVHYRSWDASTKNPYVYPAAVSQKVVLHNDIRSRRVIGQVEEIQFGASGSTSVNDNGRPNSPTQNRTLNGTADVADEEIAGEDILNFAAQEEDVLDERHLDDTQFVDEVEIQYVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU21</accession>
    <name>A0A8T0HU21_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG246800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU21"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13424" checksum="9D3D824C0E814275" modified="2022-10-12" version="1" fragment="single">MQVGMAYQDNGFAGRHSTYFNCLGQNPRNASYPHRGCSWYHSKDCFPLIESACVDGAVQFPNLLGTMATNSDGSSSNAGQATSNGHMPVISTYLQRPPYMHSWGQQMMYGGNVSSVMEQAAQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXQ9</accession>
    <name>A0A8T0HXQ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G021000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019176">
        <property type="entry name" value="Cytochrome_B561-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21780:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09786">
        <property type="entry name" value="CytochromB561_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="727" mass="79630" checksum="53013B551039CFFF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYH8</accession>
    <name>A0A8T0HYH8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G023300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYH8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035758108" evidence="1">
        <location>
            <begin position="25"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="24102" checksum="536AD38E7C1C4EB4" modified="2022-10-12" version="1">MGSTGAAVIIIGAVLLFCSLHVDAKVRFNDVDNCGKCKHKCPRAPPHSERTCKRGMCGTKCKSGWKDCDRKKANGCEVDMKTDVKNCGSCGNVCPTVRTPDGNAVATCTNGVCGSALICPTGLADCDGDLSNGCEIDLVGFAATAINCGSCGNICPLSTNKTAFSYCNSGVCTFLCNFFDGFLGVEDCDGDMSNFCEVNTRNDVNNCGGCGNICVAPPGGGQISCIEGTCTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZW7</accession>
    <name>A0A8T0HZW7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G079600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZW7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010530">
        <property type="entry name" value="B12D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33919">
        <property type="entry name" value="OS09G0127700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33919:SF1">
        <property type="entry name" value="OS09G0127700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06522">
        <property type="entry name" value="B12D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="220" mass="24126" checksum="27B9662B69FB440E" modified="2022-10-12" version="1">MKLLEQVVRNLRSTASARAAGLQEQRRQVSTQPAKYLKENADTTKLSTDEAAKLGAAKKPPGSDKGPGSFMHQQSNLATKNNKFLQPWLLPIYPMVGMVAIGVSLAVMTAYRELVVNPGVVLDKSKRTEELPELHDQEWVMKMSRRYAEDSPLRSLSHEHKVSPFGRHLDEDVKEGPAIEIAHKAMPSLKGAAPKLPGDDKPVVGPGPEEQKPRPLGGNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1D0</accession>
    <name>A0A8T0I1D0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G103000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1D0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="9014" checksum="B98F02A69829733E" modified="2022-10-12" version="1">MNHFYHNAFQKRRRSSYRVTCALSSTISLRSALGILVMTIISEWLIHSKHLQSCFERFIRCGLMRRYQIWPCLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5C9</accession>
    <name>A0A8T0I5C9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">IFT121/TULP4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G003200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5C9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056159">
        <property type="entry name" value="Beta-prop_IFT121_TULP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF5">
        <property type="entry name" value="LD29485P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24797">
        <property type="entry name" value="Beta-prop_WDR35_TULP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT121/TULP4 N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF24797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0578169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="379" mass="42507" checksum="358A07665F89610B" modified="2022-10-12" version="1">MFLYLSKKISMPNGLRVSSLSWNSEQGWLACGGETGLLKVLKLEPRAANEGKKSPFVAAPSNLSMNQTLEGHHGTVLAVNWNQNYRKLTSSDEKGLIIVWVLHKGMWFEEMINNRDKSVVRDLRWSADGQKICIVYEDGHVVLGNVDGNRLWGKTLDVQLHLVEWSPDSRLILFCTALGTCQIHDLKGNFVAQLGIRFTEREFAPTAVIVAIDWYNGLEGYSDPNAPSLALAFQLGRIQLMRHEMDEEPILLELQMMITSIKWSPDGEVVGVVGSDVSTNGKAPSSIVQLFSHTGMHLRTLRVPGTRTSALSWEGGGLRLALAVDSYIYLANIRPEYKWAFFGSSTCMYSFKKRDHLDHSVMFWDIGTGERVRNQISMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7T5</accession>
    <name>A0A8T0I7T5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G068200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7T5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="20675" checksum="1A4A828A3E397D41" modified="2022-10-12" version="1">MVSSLLSLSGRLASSTVLLLGLLLVGDGGRLRRSSADLNAARLQLLLLHLRHHHRQHAAVHLRRDVVQIGTLREPELAHEAPAAALHAVPGIRLLHLLLLPLPADAQRAPVLDLHPHVLLAQARQVGLEHVLRGRLLPVHARAGHGARVASERGRGGVVEERHHRLQGVGHCVPHVVPAPEERRECHCSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9G6</accession>
    <name>A0A8T0I9G6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G109800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9G6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10123" checksum="F6D72C52921899A6" modified="2022-10-12" version="1">MDKERRDKISQYMAQSRVSSPSFQHISLHSQQQRSRLSIQQKKIIHDDCAKIKEAKLKAGIAAQKRAEAFEKSAWGKAAKKAVIAAKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9N5</accession>
    <name>A0A8T0I9N5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G079900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035898164" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="68" mass="7505" checksum="0CF767AD1902F241" modified="2022-10-12" version="1">MIVSSSSTTRMLSLVWLSRSAGVVGSDRCRVVLYSNYCPLDPALKCRFSLAQSIPTKTRVRCALPNIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAP5</accession>
    <name>A0A8T0IAP5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">IAA-alanine resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G200400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAP5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006882">
        <property type="term" value="P:intracellular zinc ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950">
        <property type="entry name" value="ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16950:SF16">
        <property type="entry name" value="ZINC TRANSPORTER ZIP13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035804987" description="IAA-alanine resistance protein 1" evidence="7">
        <location>
            <begin position="38"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="602"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="630"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="662"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="209"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="378"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="259"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="455"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0580800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="73548" checksum="0850D50E7BB58BF9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB73</accession>
    <name>A0A8T0IB73_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G159400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB73"/>
    <dbReference type="OrthoDB" id="513821at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36333">
        <property type="entry name" value="DIMETHYLALLYL, ADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36333:SF1">
        <property type="entry name" value="DIMETHYLALLYL, ADENOSINE TRNA METHYLTHIOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="29899" checksum="1D2686C84C40D050" modified="2022-10-12" version="1">MIAAMEVASTCCSMSRTCAVAPSSSFTQQLAAPAFRTNLRLKQVGAWQAPQRGLIQITNIGWDPEGILPAPVPHHITRRSYEKKISEDAEYKEKVERQLQADKEARRQAREARVVPDSHKDLLEFLLSTEGSEMEFEVARCRPRLTEDFFSFVKAEIGSLRFAVNQTVEVQDRIGELEVLQKVLQEGVGAYDALTTDLVDAKERLQRILVAKDKKAILLEMAGENQLDRPLLALLDENIVSATQANEEQAALFMSKIRGAVVKYITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBC0</accession>
    <name>A0A8T0IBC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G159000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00267">
        <property type="entry name" value="ABC_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32114:SF2">
        <property type="entry name" value="ABC TRANSPORTER ABCH.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="95"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="RecF/RecN/SMC N-terminal" evidence="3">
        <location>
            <begin position="501"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="645"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="833"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="961"/>
            <end position="995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1201" mass="133993" checksum="75EAADEB89E13036" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEI0</accession>
    <name>A0A8T0IEI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dynein light chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G038700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
            <location evidence="1 8">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the dynein light chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEI0"/>
    <dbReference type="OrthoDB" id="10033309at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005868">
        <property type="term" value="C:cytoplasmic dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21452">
        <property type="entry name" value="DLC-like_DYNLL1_DYNLL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.740.10:FF:000001">
        <property type="entry name" value="Dynein light chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.740.10">
        <property type="entry name" value="Protein Inhibitor Of Neuronal Nitric Oxide Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037177">
        <property type="entry name" value="DLC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019763">
        <property type="entry name" value="Dynein_light_1/2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001372">
        <property type="entry name" value="Dynein_light_chain_typ-1/2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11886:SF35">
        <property type="entry name" value="DYNEIN LIGHT CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01221">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01375">
        <property type="entry name" value="Dynein_light"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54648">
        <property type="entry name" value="DLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01239">
        <property type="entry name" value="DYNEIN_LIGHT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="5 8" id="KW-0243">Dynein</keyword>
    <keyword evidence="4 8" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6 8" id="KW-0505">Motor protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11370" checksum="40E98959A76E6673" modified="2022-10-12" version="1">MAEKIVEKSGILERKAIIKNADMTEDMQQDAIECATAALDKYNVEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFVYFYLGQVAVLLFKSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFH6</accession>
    <name>A0A8T0IFH6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G236700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFH6"/>
    <dbReference type="OrthoDB" id="1980105at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="126"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="446" mass="49863" checksum="CE81B1E4FC3857D5" modified="2022-10-12" version="1">MTTQRLSARLPERPKAPQWSSSTEITRSNPKSKGAQLRAATLAVDARLKGDKKLVHASRRVSVELARVTCECRSRGIETCSTSCACVVKWKSCGVECECHGSCCNSLVHTPRVGIRSGALGEEFYTKVDLPRGKVAFVVCGRVMSLPEYWRYHEKVTGNPYGNAVRHYGFPILWQGVLPVKYVVDPFEDMTGAVNHSCEPNVVVEACWTNGKIYAVGRTTCNVMAKEALCVDYKWKGTTNPKEFAEICRCREAKCRGLIAEKGSKFMEVSTLHYEGEITRLQEEHAIAEKALQERYGVLAAAEQAGSIGRAEIETELIRKENENEKLKAHIEFIIAAVTRSKASLAEYSIVTEYVVEIPQKEKIHVSPLQKFIQRIRNMFSKRQEEEEEVQAQITISSETNPYFAPDSALLSHRSILPEPSASLSTPRSCPPTVRQRVVPRYLPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFI6</accession>
    <name>A0A8T0IFI6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G270400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11872" checksum="FDECF660929C2EC1" modified="2022-10-12" version="1">MIRTSSFAVTRQFRRVNWLGMIDCRGREGGRDQRQTMDGMCSIWECGDEYVTTPKLNLPALARPPSRPEQSRAVGRQRAVQWGRALVGSDVGRRSGCTQSIGTKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFX4</accession>
    <name>A0A8T0IFX4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G073700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFX4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="245"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="613"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="694" mass="77865" checksum="92954ED70EC169B8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGZ4</accession>
    <name>A0A8T0IGZ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G048700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGZ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035772472" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="39" mass="4585" checksum="763DC21256F3C8D1" modified="2022-10-12" version="1">MGIFLSAFRLSLFISLLRFFEMGCCHGRRAFVNSWPFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH27</accession>
    <name>A0A8T0IH27_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Homologous-pairing protein 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G036100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HOP2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120231">
        <property type="term" value="C:DNA recombinase auxiliary factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120230">
        <property type="term" value="F:recombinase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007129">
        <property type="term" value="P:homologous chromosome pairing at meiosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000709">
        <property type="term" value="P:meiotic joint molecule formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010774">
        <property type="term" value="P:meiotic strand invasion involved in reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010776">
        <property type="entry name" value="Hop2_WH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040661">
        <property type="entry name" value="LZ3wCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15938:SF0">
        <property type="entry name" value="HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15938">
        <property type="entry name" value="TBP-1 INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18517">
        <property type="entry name" value="LZ3wCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07106">
        <property type="entry name" value="WHD_TBPIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homologous-pairing protein 2 winged helix" evidence="9">
        <location>
            <begin position="9"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine zipper with capping helix" evidence="10">
        <location>
            <begin position="149"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="81"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0582127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="224" mass="25111" checksum="093A4C0FC45EDDF4" modified="2022-10-12" version="1">MAPKADSVEGTILGYINEQNRPLNVQMVADALQKNGIKKTAVQKVMDTLAANGKISFKDYGKQRVCMADQTQFEIPDIDELDAMKKQNDQLLADVAAVRSRVSELESGLKSAETNLTLDAVVKKTKELGSEVETMETKVQALREGSVLVTPEERLEVQAAYDLKLGVWRKRKKIYHELWGMITESMTENLKDLKEEIGIETDEDVRCNITDFSNLGVKKQKNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHF1</accession>
    <name>A0A8T0IHF1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G052700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHF1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="80" mass="8400" checksum="CB173844C36B5153" modified="2022-10-12" version="1">MPLSSVKTSKQTHTNICLIGRSSGDSFQLKFECKTGNPGFVVIQPSENEDDDGGNNSSLAVLDKTVSVVELGMNMAGVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHH9</accession>
    <name>A0A8T0IHH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G062000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025066">
        <property type="entry name" value="CCDC174-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15885:SF1">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="144"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="203"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="29381" checksum="A17198D04FF270A5" modified="2022-10-12" version="1">MEGAGEKRERDARRVDSLGWLTESAVMPKKQRAIEGVGPSSIVELRAQLYRTHEDVKRAKELGVDPDVFRPKKKLDAFLKKNSGVEDRATRDKLHLKATKDGVDSYAALEKKAELYDKLVRGELPDEEEKEKYSVDFLRKGSLDDEAQEMERDRLGDSRHDGRENFETAAVFDGGTSDEKPKSGVGWGLGKSTGLSLEQKQLIREVNVETKEARGKAVELKQRRQVQAEKNREKLRLAFLKKQVEKLRSSGGLQEKTEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHU1</accession>
    <name>A0A8T0IHU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Oxidation resistance protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G063600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHU1"/>
    <dbReference type="OrthoDB" id="26679at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006571">
        <property type="entry name" value="TLDc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354:SF62">
        <property type="entry name" value="MUSTARD, ISOFORM V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23354">
        <property type="entry name" value="NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07534">
        <property type="entry name" value="TLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00584">
        <property type="entry name" value="TLDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51886">
        <property type="entry name" value="TLDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TLDc" evidence="6">
        <location>
            <begin position="196"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="167"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="376" mass="40557" checksum="405DFBBD3EE41734" modified="2022-10-12" version="1">MKKALLSKPGEWADKVGDKLGGLLPSKKNKAPLPRKNSAPNLVNYGADADADVRLGGQGWDASDNENSGRGSPDPPGPDTSSLSAFLMNLLSSEKGEKEEKGTLGFGWGGSRPGVVASRSGDQTPDRSRGRGEQCVSGEVHEEGNTQRGEFYDVDWLLVDEHVKVSNPVSIPPKPQKKQLPSISSDRLPRMSDDSSLLSDDVRCCIHPALPTLAKGRRWVLLYSTEKHGMSLLTLYRNSNMMTGPLLLVAGDKEGAVFGGLITAPLVPSPKKKYQGTSDSFVFSNVTGEPTIFHPTGANRYYVLATTDALALGGGSHFALHVDAELLNGSSGVCETYDSPCLAHSEEFILKHVELWGFDHTQRHSSFSEPSPLMTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II98</accession>
    <name>A0A8T0II98_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine amidotransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G067300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II98"/>
    <dbReference type="OrthoDB" id="92161at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695:SF5">
        <property type="entry name" value="GLUTAMINE AMIDOTRANSFERASE YLR126C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase" evidence="2">
        <location>
            <begin position="169"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="40644" checksum="F17304B9180F3C27" modified="2022-10-12" version="1">MACRRLLHTCAKSSPSGLLSGRIAPAAPKSLACKAPAPTSRLFSSNLGASGSGASLGFSSRLGSRFDSLRFSRGGWIISRQSVVRIALDHSMAMGSSVVANGDVGPTQAVGAETVAKPRRFAVLTTGHAAEYCVNKYGGYGPMFITMLSDPGEIWDEYFVVDGQFPSLEELQKYDGFVVTGSRHDAHADEEWIERLCGVLQRIHEMKKKSLCVCFGHQVVSRALGGKTGRASVGWEVGLRDVCLTDAFFSKSYGAGMPPKLKVLEVHRDQVSEIPPGAELLASSERTGVEMFSVGEHVLAIQGHPEFYDDVVVDLLDGRLAPMMTKEEIMLAKESLQKARADQKSWQQLCKDFLKGSRSSTPEHLVYSREALTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJJ4</accession>
    <name>A0A8T0IJJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G174600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.50:FF:000026">
        <property type="entry name" value="Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006740">
        <property type="entry name" value="DUF604"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10811">
        <property type="entry name" value="FRINGE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04646">
        <property type="entry name" value="DUF604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="505" mass="56922" checksum="2D5D95A8517B0CE2" modified="2022-10-12" version="1">MFRGNQLTRGPARKAFWSTILVLVTFLGVGTTVWLSLVFSSHRSPCIADMHSIPAPPSNFWLTSSSSSHEPASFSAPPYVHPSPPNNRLAINQVVFGIAGAAQLWDKRKEFIKLWWRREEMRGFVWLEEAVKVQEGANLPPVHVSEDTSTYSYTHPLGHPSGIRLSRIVCETFRLGLPNVQWFVMGDDDTLFNTDNLVRVLSKYDPSEMWYIGSNSESHRQNDHFSHSMAYGGGGFAISYPLAEALTAMQDQCLERYPSLFGSDDRLHACITELGIPLTRELGFHQFDVFGNAHGLLASHPVTPFLSMHHLELLAPVFPYMSHLEGLRLLTKAMRTEPGSFLQQSLAYDQKNSLSFSISTGYVIQVFPEIILPRLLTRVETTFTAWNRDNKPLEFAFDTRPSPTSVCKQPYLFYLDDISYDSVASRVVTVYKRYESIDDEKSKNFCWSKGLPRSKVKSIEVVSEPVSSKFFSLPRRQCAKLMGTKDQVLHINVGACQPGELITAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJW9</accession>
    <name>A0A8T0IJW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G182600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5718" checksum="040F36DFDF104476" modified="2022-10-12" version="1">MTQMKGTLFIVDHKEVSLHGWIMGCYSTIELQASHRDSWLCGLRAAFFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKC8</accession>
    <name>A0A8T0IKC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G139200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035926165" evidence="1">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6370" checksum="850446D1372C1BED" modified="2022-10-12" version="1">MIRSGTMRFQFLFLLRFLQVELNSHFFRICSCSLITNSSLHVWTTARCGLNTGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILJ4</accession>
    <name>A0A8T0ILJ4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G163000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035792968" description="Secreted protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="60" mass="6795" checksum="246666A4A272D0E4" modified="2022-10-12" version="1">MSSWINCSFCLLVLFYTNRGPSTADGSNEYAHPASYSQRLMCMQSVRSVTLSSARFDRCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILS1</accession>
    <name>A0A8T0ILS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G230200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILS1"/>
    <dbReference type="OrthoDB" id="193499at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12347">
        <property type="entry name" value="RRM_PPIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000557">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034168">
        <property type="entry name" value="PPIE_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037">
        <property type="entry name" value="ATPASE E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48037:SF1">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="7"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="155"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="18603" checksum="D7420066682BD87B" modified="2022-10-12" version="1">MAANPKTTLYVGGLEENVTEQVVHAAFIPFGDVKDISMPLDQATQKHRGFAFITYFEKEDAAAAMDNMHNGELYGRVLTVNFAQPQKIKGGEQGWASQAVWADADTWFERQQQEEEMKRLNAEHLATVSAAEEAERKKLKEVREGETEADDAVEDPMAAAEAEALKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ24</accession>
    <name>A0A8T0IQ24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G259000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13899" checksum="56B2AE6AE17CE48F" modified="2022-10-12" version="1">MAKRAEEDSNVPFSVLVGFSSEGERSNTGYPGDYAREVRAQSVVKKRVLCLVAMRVGVIRRRCRYGRCLLLFRSNSLVKHLASFRIDQVLAAAEAIPCRRSTSRAANHSSWRCNMPFPRPKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQI9</accession>
    <name>A0A8T0IQI9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G056700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQI9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="143"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="445" mass="50629" checksum="69598D3C7BD340C3" modified="2022-10-12" version="1">MASTSALASELKEMQLSDPSCTAGASMETEFHTALQPESECATSASSSFLTALGSESVLESGKCSSDVEREQRIENSRSHWSVVKATVISDGDGAVEEDNRKVFRELQSHPTWGEFFTTFGYDLGVPYPGMPGYVCGSSGELVMEGKPFAEGAQAELFHARVTWRSPKMKEYDLKEGREWVVKVFKKGTSLRQLREQWPHGYLQYIGQEYATNFGVIRYHCDVTFGILLKDGRFAFLMKREQEDLRCHIERGMLEIGGGRVPFTKEQRDFVMCQMAKGMEWLHEHNIVHRDLKASNVLVSRGGNILVADFECSIGVIGTGFWRAPEILQAIKDKKVNERPEVFSKEADVYAYGMTCYEILTGKVPFGDHPIWDYSIVLNGGRPELPKYVEDWMRDLMKRCWEHDPKKRPSFKDILNILVTYSASVRDDLERERIYLENMRSKAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQK4</accession>
    <name>A0A8T0IQK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Vesicle transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G256500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the SFT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007305">
        <property type="entry name" value="Vesicle_transpt_Got1/SFT2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011691">
        <property type="entry name" value="Vesicle_transpt_SFT2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137:SF36">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN SFT2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23137">
        <property type="entry name" value="VESICLE TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04178">
        <property type="entry name" value="Got1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0585081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="28933" checksum="8BEC100991916575" modified="2022-10-12" version="1">MQEVKGNLQELNIQGKIHDLNLQGKVQDLFNRDQAGSAAAEPMNAQSGGVLSAWNTYAARQQQQAPEAATHGAPGRDLESGVPESLAPLLKSANSSITNAFNSVTNKVRELPANVQSAASFVPSRQALTAFFIMIAAGSFFIFMAFFMFLPVIVLVPQKFAISFTIGSIFIVGSFFALKGPKAQFYHMVSKERWAFTAGFIGSMAATIYVSVVLHSYILSVVFAVVQVLALLYYLMSYFPGGTAGMQFLTSMIMNSFTKCFGRLTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQS2</accession>
    <name>A0A8T0IQS2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G231000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15609"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.6.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002189">
        <property type="term" value="C:ribose phosphate diphosphokinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006015">
        <property type="term" value="P:5-phosphoribose 1-diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000032">
        <property type="entry name" value="ribose-phosphate pyrophosphokinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000034">
        <property type="entry name" value="Ribose-phosphate pyrophosphokinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210:SF45">
        <property type="entry name" value="RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01400">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribose-phosphate pyrophosphokinase N-terminal" evidence="13">
        <location>
            <begin position="75"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="12">
        <location>
            <begin position="280"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0584733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="384" mass="41562" checksum="15B891285B2F4CDC" modified="2022-10-12" version="1">MPQMQPQEAAAGGRAGAGAGAGEGEASAPGPPTSDIYAGISTIPISAALIGSGVDANELVGDVIDQPKTNKKLVYLFYCDETEELARRIAAETDSVELRSIKWGTFADGFPNLFVPNAHGIRGEHVAFLASFSSPAVIFEQLSIIYALPRMFVSSFTLVLPFFPTGTLERMEDEGDIATAFTLARILSNIPCSRGGPSSLVIFDIHALQERFYFGDNVLPCFESGIPLLKHRLLQLPDSNNVTIAFPDEGAWKRFYKQLQHFPMVICTKVRDGNKRIVQLKEGDPTGRHVVIVDDLVQSGGTLIECQKLLATMGANKVSAYVTHGVFPKRSWERFLHDNGEGAAHGFAHFWLTDSCASTVKDVKGVKPFEVLSLAGSIAVALHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQU5</accession>
    <name>A0A8T0IQU5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G065300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080037">
        <property type="term" value="P:negative regulation of cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000762">
        <property type="term" value="P:regulation of phenylpropanoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044595">
        <property type="entry name" value="KMD1-4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46407">
        <property type="entry name" value="OS02G0208700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46407:SF3">
        <property type="entry name" value="OS02G0208700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="459" mass="53032" checksum="E135E4E4645D8A81" modified="2022-10-12" version="1">MAISKQEYVEQELIPGLPDLLVTYFILPRLPWYTRVCMLSISKAWKMVFDNSSFLDTRTKELYKPRGLFLIHELLDNTSCGCEEELFSKSPSARLSSQDSDEESSEIYLLQKYAIEMCDMHDRIWHRLPPIPSCPSGIPSRCSFVCLDGKLFVMGGIPDSTKAKESADMHMLNIGLGHWWWEQCASMHFSRAFVKCAAHDGQIYVVGGTCPAEVYNVNENQWHRLPEMVDVQFFCNGILALGNQIIAYGYDILDPEVLVEPDVNSARVYDLLSKNWSTVEFDFTKCCTSASGHLMLDIVDGMLVTYDITTHNTTLYDGRLHIELSPSKFHAMFKLSYHLIFQLYFYMRMVHCVHGFEDWKIDMIPFERELGNQTPLFYIDDDYIYHPSFQVFDIVVVESPSKPTQVYTLFSPYGSRLHQLWRGTIDFDACKVIWDQDIICPFKLCQLDTENSSKLCYMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR76</accession>
    <name>A0A8T0IR76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G002300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005834">
        <property type="term" value="C:heterotrimeric G-protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001664">
        <property type="term" value="F:G protein-coupled receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031683">
        <property type="term" value="F:G-protein beta/gamma-subunit complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007188">
        <property type="term" value="P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00066">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000720">
        <property type="entry name" value="Guanine nucleotide-binding protein G(k) subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.400.10">
        <property type="entry name" value="GI Alpha 1, domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001019">
        <property type="entry name" value="Gprotein_alpha_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011025">
        <property type="entry name" value="GproteinA_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218:SF334">
        <property type="entry name" value="EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10218">
        <property type="entry name" value="GTP-BINDING PROTEIN ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00503">
        <property type="entry name" value="G-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00318">
        <property type="entry name" value="GPROTEINA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00275">
        <property type="entry name" value="G_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47895">
        <property type="entry name" value="Transducin (alpha subunit), insertion domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51882">
        <property type="entry name" value="G_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0807">Transducer</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="827"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="82"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="278"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="827"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="765"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="1066"/>
            <end position="1069"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1136"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR601019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1196" mass="132552" checksum="9F10CFABF4860923" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUD0</accession>
    <name>A0A8T0IUD0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G113900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="9937" checksum="8D7BAC6A01927C7D" modified="2022-10-12" version="1">MNQAMCAGVQYHSEIVFCSVRGFIVYFAGWGDEGGNWMHVNFETSNNLCHFISCSFFVGCKLAEEYNLCRRANSKVQVQSTVATLLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVY5</accession>
    <name>A0A8T0IVY5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G156300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035826318" evidence="2">
        <location>
            <begin position="38"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="421" mass="47058" checksum="7B732D09B1C81F21" modified="2022-10-12" version="1">MHKMMSQCGKLGSSISSSLRCALYVVSMACLWAMVAAQAAAPPPMSAPPPMSDPPAREGCSRELVSTVWGFILTFVALTLDDWGIQKNAADDYIWKTMKVIFMGPANPISALFFKLNDTMNSRILRKWLSTPEERVYIRTLAACKVVVNLSPAAYGDFHGKLDKLHVHEEVVEVKDFSDAFVLGNEVLDRKETNVQLTTVGKAMLVKAGALPPIERLKILQGNSGLAIAVAAAQGGGYIYGVMVRVVQRHHVSPIEAIGFYMSSFTLVRAVCHYFTSSCHRPLYLFLDDVMEKDFIKKCQEYESNKDVHVPQNPWKFKNRLITTVILSLVYSNLLFFFVYGICSTSSMMVIPLVILMSLPFSWILILFTTEISFSTLLIITPIVHIVAYIFSLVLTWKYWNSFGYDIPTSGYVAKILPYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZS8</accession>
    <name>A0A8T0IZS8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G239900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045277">
        <property type="entry name" value="DRE1A-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839:SF2">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="10">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="11">
        <location>
            <begin position="244"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="100"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0588389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="44431" checksum="D5405D9D8865D04D" modified="2022-10-12" version="1">MEREEEQKWAGEQEWDGEQEVEGNRLVEQLRKALLNSPSEQAPDNSPAFEEVIGIDHSFIPSFNHLQLQTRVRNMSIEPPAGELLDRIDNTDYRVKLRSYSSFPTPTSNPAVTVSDTSSQCTNTERADSIFDQSLSDGDGSGDRRRKRPQTRQHRGSIQSRGKSHAEHLQNFADAAHSGPSRRSYECEVCKKFFHSPQSLGGHKNLHRSKGKPRRYRAARTVDLVGGQAGSGSNSSESETVSSLYKGVRCREGDKWVTEIRPPRSSEKWWLGTFPSAEEAAQAYDVALAFFKSDSELNFGYHPLYQKFPPLPPPNLSPHKYAQRLRGMVKEISEQIIAERRRTEEQAVFLSSFGGPAVSPAGSSSSTADPTTLQDWHALVQDLPANECDWIKFLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZX0</accession>
    <name>A0A8T0IZX0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G231200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="14600" checksum="FD0B6922D09F08C0" modified="2022-10-12" version="1">MDFYDRHIGRRSLRIRPRPAPRLLHSGRVELDARKRLRMLRPIKGQERGLRVPRPAQSGRHDQRVRSSDHASVRQTMARAQHAGHLLGARRLCSEWSKQPALAPARQRDFLLPGGDAPRGLRGLDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZZ1</accession>
    <name>A0A8T0IZZ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF7032 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G243600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000225">
        <property type="entry name" value="Armadillo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054296">
        <property type="entry name" value="DUF7032"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46043">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46043:SF13">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00514">
        <property type="entry name" value="Arm"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23005">
        <property type="entry name" value="DUF7032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00185">
        <property type="entry name" value="ARM"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50176">
        <property type="entry name" value="ARM_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="584"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="616"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7032" evidence="3">
        <location>
            <begin position="32"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="205"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="287"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="ARM" evidence="1">
        <location>
            <begin position="370"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="649" mass="70671" checksum="49008BB099288854" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J042</accession>
    <name>A0A8T0J042_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G247400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J042"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19431" checksum="77ABB704702EFEB8" modified="2022-10-12" version="1">MLFLHFHVGLWSKMPLGELKPLLTHILPAGVMERLSFVYSRSDLIDRENFPWSYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRRTPNCMCYILWPFQGHLNFPNDDGVIPNIATDILPLVYPLHKFGSVPEYMAQACRPGQVHWAIEAARKFGRARVDWTEVCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J084</accession>
    <name>A0A8T0J084_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Plastocyanin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G017500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
        <text evidence="9">The crystal structure with reduced Cu(1+) has also been determined.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Plastid</location>
            <location evidence="1 10">Chloroplast thylakoid membrane</location>
            <topology evidence="1 10">Peripheral membrane protein</topology>
            <orientation evidence="1 10">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the plastocyanin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J084"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009543">
        <property type="term" value="C:chloroplast thylakoid lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04219">
        <property type="entry name" value="Plastocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001235">
        <property type="entry name" value="Copper_blue_Plastocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002387">
        <property type="entry name" value="Plastocyanin"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02656">
        <property type="entry name" value="cyanin_plasto"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34192">
        <property type="entry name" value="PLASTOCYANIN MAJOR ISOFORM, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34192:SF10">
        <property type="entry name" value="PLASTOCYANIN MAJOR ISOFORM, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00156">
        <property type="entry name" value="COPPERBLUE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00157">
        <property type="entry name" value="PLASTOCYANIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 10" id="KW-0186">Copper</keyword>
    <keyword evidence="5 10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Blue (type 1) copper" evidence="11">
        <location>
            <begin position="72"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR602387-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0589380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="167" mass="16950" checksum="321CE69A2D350810" modified="2022-10-12" version="1">MASIAAAVSVPTFSGLKAESKAAPAQVVSSSTVVRMAPVRASVSNETLKNVGKALFAASSSLLLAASANAATVKMGGDDGTLGFFPSSISVAAGESITFVNNKGFPHNVVFDEDAVPGGVTVDALNHEDYLNAPGESFTVTLKTAGTYEYYCEPHQGAGMKGSITVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0K8</accession>
    <name>A0A8T0J0K8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G265900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0K8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035941752" evidence="2">
        <location>
            <begin position="19"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="8361" checksum="1ADE47893E543D9F" modified="2022-10-12" version="1">MVVCWLCGGCVCCGGCLCGLEVVECLGIHVCGVSGVGDGTVGGMGGLVVFLGGCGVCLLEFVACWLRMRGLCWKCVLGEGSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J179</accession>
    <name>A0A8T0J179_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Floricaula/leafy-like transcription factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G039900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable transcription factor.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FLO/LFY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J179"/>
    <dbReference type="OrthoDB" id="1875842at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4180.10">
        <property type="entry name" value="Protein LEAFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035209">
        <property type="entry name" value="FLO/LFY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002910">
        <property type="entry name" value="FLO_LFY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038276">
        <property type="entry name" value="Floricaula/leafy_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035079">
        <property type="entry name" value="LFY_SAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36079">
        <property type="entry name" value="PROTEIN LEAFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36079:SF1">
        <property type="entry name" value="PROTEIN LEAFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17538">
        <property type="entry name" value="C_LFY_FLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01698">
        <property type="entry name" value="SAM_LFY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 9" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Floricaula/Leafy protein SAM" evidence="11">
        <location>
            <begin position="40"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Floricaula/leafy DNA-binding C-terminal" evidence="12">
        <location>
            <begin position="183"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="154"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="169"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0589690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="349" mass="40334" checksum="6D904E6684FD44FB" modified="2022-10-12" version="1">MVDDCPVHNMQATFDIVQAEPTALLYKRPDGAALAGRESRRLKELFKDFGVQPSTVAVMGQMGFTLSTLVNMKDEEVDFLIKSMIEEYHLDLLMGEQFGIKAAIRAKRRVLEEETEQQRMDLINRSNEKKRRVEEPSDGLLLKDGHTSLEALGLLGLTDPESDSEGKKVTKRRQRKRRSKEVGEDGEERPREHPFIVTEPGEPAKGKKNGLDYLFDLYEQCGKFLEEVQHIAKEKGEKCPSKVTNEVFRHAKLTGAGYINKPKMRDYVHCYALHCLDVDMSNNLRKEFKERGENVGAWCQACYFPLVQLARSNEWDIDDLFNRNDKLRIWYVPTKLRQLCHIERMKHCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2U0</accession>
    <name>A0A8T0J2U0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fructose-1,6-bisphosphatase, cytosolic</fullName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_1G009300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2U0"/>
    <dbReference type="OrthoDB" id="10256725at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000001">
        <property type="entry name" value="Fructose-1,6-bisphosphatase class 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000008">
        <property type="entry name" value="Fructose-1,6-bisphosphatase, cytosolic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006778">
        <property type="entry name" value="PRK09293.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006779">
        <property type="entry name" value="PRK09293.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF41">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE, CYTOSOLIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="14">
        <location>
            <begin position="13"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="15">
        <location>
            <begin position="205"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0589278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="36681" checksum="8D16DF3FA5C8ACB7" modified="2022-10-12" version="1">MDHAADAMRTDLMTITRYVLNEQSRFPEARGDLTILLNNIVLGCKFVCSSVSKAGLAKLIGLAGETNVQGEEQKKLDVLSNDVFVNALVSSGRTNVLVSEEIEDAIFVEKAKRGRYCVVFDPLDGSSNIDCGVSIGTIFGIYMLKDGIEGTVEDVLQPGTAMLAAGYCMYGSSCTLVLSTGAGVNGFTLDPSLGEFILTHPDIKIPKKGKIYSVNEGNAMNWDAPTTKYVQNAKFPKDGASPKSLRYIGSMVADVHRTLLYGGIFMYPGDKKSPKGKLRVLYEVFPMSFLMEQAGGQAFTGKERALELVPTHIHDRSPIFLGSYDDVEEIKALYAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J331</accession>
    <name>A0A8T0J331_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DOG1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G058900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J331"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051886">
        <property type="entry name" value="Seed_Dev/Stress_Resp_Reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025422">
        <property type="entry name" value="TGA_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46354">
        <property type="entry name" value="DOG1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46354:SF27">
        <property type="entry name" value="DOG1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14144">
        <property type="entry name" value="DOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51806">
        <property type="entry name" value="DOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DOG1" evidence="3">
        <location>
            <begin position="54"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="336"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="369"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="433"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="533" mass="58385" checksum="1880DC84151DDB01" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J383</accession>
    <name>A0A8T0J383_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G014500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J383"/>
    <dbReference type="OrthoDB" id="1663137at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000073">
        <property type="entry name" value="12-oxophytodienoate reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="29"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0589341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="43762" checksum="BEBA6CC0DCA4AAF8" modified="2022-10-12" version="1">MDCYWTYHNRICSKESGEDEKHERMPLGTPYKLGRFQLHHRVALAPLTRCRSYNHLPQPHAVLYYSQRTTPGGLLISEATGISDDCHGYPHTPGIQTDEEVEAWKPIVKAVHDKGGIFICQIWHTGRVSHTSYQPGGAPPVSSTNRAIAKGEVTLPTGVGTAPFSTPRALKTEEIPTYVEMFRVAARRSIEAGFDGVELHGAHGYLIEQFLKSSVNDRTDKYGGSLENRLRFLLEIVEAVSEEIGADRLGVRISPFTDYAESEDADAVALGVAIAEALNKFNLLYLHCVEPRVAKNDTHFIETDRTLWPVRNAFKGSFLSAGGFNRAEGNDAIRTGRADVVVFGRHFLANPDLPKRLAMCAPFNKYDRSTFYTQDPVVGYTDYPFLEEISAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J737</accession>
    <name>A0A8T0J737_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G169500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J737"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035797256" description="NADH dehydrogenase subunit 1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="52" mass="6109" checksum="9DFE11F69F9D6B33" modified="2022-10-12" version="1">MLCVLRLLCSCLMWLTTLPSFFPMKYHMKWPPPGICLCCWGFKIFYTGGFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7M3</accession>
    <name>A0A8T0J7M3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G160700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7M3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="89"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="225" mass="24598" checksum="3E383AD7A27006FC" modified="2022-10-12" version="1">MATMERPAAVTTDRAAMGNTVGANPSMVNSVGANPSMASSVDTNPSMAKSFGSNSPTSPSVRNLKAEAFGDAHRQRVEAEVNAYLLSETRKAEARAATAESRIEQKRMKDEARAIEHKKREEAKAEQAVRAAEVKADKIIANAKEEAVRMKAYAAEECEKGIADAHTQAERAKAEQEELKIREIAELKDRAEQMRITGELPFYEKEKKGMGTKMKHVLTCHHGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7X6</accession>
    <name>A0A8T0J7X6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G147800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7X6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035896299" description="C-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="271" mass="30277" checksum="0F9DE135BDB3523C" modified="2022-10-12" version="1">MAKLSSVILGALLLLLVAQCATAARWTSPVRGGCLRRGTRRWTATLVDFGPDGLGLCRRTYANIGGQRFNGANECRQAGRGIIGTFYVNDRTCTRFTDQEAEAVVPVTEEMVTVIEEVVAVTEEVAPVFAPHWGRFHRDGCLRKKRGYRRWTARLLDVGSGNWNATCLRTPATIRRQKFAHPAHCRKNRKGHVIGVFYVRDRTCRRVSDLQEALELEMETVHFEEAALNLQEALAFEVESALEVEDAVNVDENEDVNVEFEAVDVEAEALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8A1</accession>
    <name>A0A8T0J8A1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G140400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8A1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035842119" evidence="1">
        <location>
            <begin position="18"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="6176" checksum="35562FB646042DC7" modified="2022-10-12" version="1">MGFLALVKLLLLFGVFSVRHWALFSTLSMSDSWEHQTDLKVPLEISFYWGVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9T5</accession>
    <name>A0A8T0J9T5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Agenet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G209100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9T5"/>
    <dbReference type="OrthoDB" id="433924at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20405">
        <property type="entry name" value="Tudor_Agenet_AtDUF_rpt1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014002">
        <property type="entry name" value="Agenet_dom_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055274">
        <property type="entry name" value="SWO1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48429:SF1">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00743">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="456"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="552"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="772"/>
            <end position="793"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="866" mass="93527" checksum="73C2AB60E438FB0C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA73</accession>
    <name>A0A8T0JA73_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-(3-amino-3-carboxypropyl)histidine synthase subunit 2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Diphthamide biosynthesis protein 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Diphtheria toxin resistance protein 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G282000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DPH1/DPH2 family. DPH2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA73"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11840:FF:000002">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.11860:FF:000001">
        <property type="entry name" value="2-(3-amino-3-carboxypropyl)histidine synthase subunit 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="entry name" value="Diphthamide synthesis DPH1/DPH2 domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762:SF2">
        <property type="entry name" value="2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="DIPHTHAMIDE BIOSYNTHESIS PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01121">
        <property type="entry name" value="Diphthamide_biosynthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="421"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0592800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="535" mass="57571" checksum="2A13F3E46295601C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAQ1</accession>
    <name>A0A8T0JAQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G283300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005391">
        <property type="term" value="F:P-type sodium:potassium-exchanging transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030007">
        <property type="term" value="P:intracellular potassium ion homeostasis"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006883">
        <property type="term" value="P:intracellular sodium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990573">
        <property type="term" value="P:potassium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902600">
        <property type="term" value="P:proton transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036376">
        <property type="term" value="P:sodium ion export across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050510">
        <property type="entry name" value="Cation_transp_ATPase_P-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294:SF20">
        <property type="entry name" value="P-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43294">
        <property type="entry name" value="SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="914"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="940"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="985"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1014"/>
            <end position="1032"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1053"/>
            <end position="1072"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1078"/>
            <end position="1100"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="12">
        <location>
            <begin position="121"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="10">
        <location>
            <begin position="247"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase C-terminal" evidence="11">
        <location>
            <begin position="937"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0592817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1130" mass="123605" checksum="6517BD6916184B8F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBU5</accession>
    <name>A0A8T0JBU5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G325600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="13822" checksum="6F32FEC03FA40DE0" modified="2022-10-12" version="1">MGAAVSRVQSRARTPVRHPHPARQTRHGLRLKPGGPTRSRFPPGPSQRDSLVASPVLSSGDPKHSVSSRIGPKELTTYSLTHSLTHSLTQTNCSRERSDLTPIHSNIASASLLVSRCGVECGRVVSWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC15</accession>
    <name>A0A8T0JC15_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G297500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007346">
        <property type="term" value="P:regulation of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000211">
        <property type="entry name" value="Cyclin-dependent kinase G-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF107">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 11A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0593005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="23700" checksum="74958C7C7C726A34" modified="2022-10-12" version="1">MLQMFHGVKYLHDNWVLHWDLKTSNLLLNNRGELKICDFGLARQYGDHLKEYTHEVVTLWYRAPELLLGAKEYSTAIDMWSSGCIMAEFLAKEPLFPGESVLDEMDKIFKCLGTPNEKIWPDFVKLPGVRCSFTKQPFNRLREKFPATGFAGRPTLTEKGFDLLNRLLTYDPSKRITAEEALNHEWFREVPLPKAKEFMPTFPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDH1</accession>
    <name>A0A8T0JDH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribosomal RNA-processing protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G305700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDH1"/>
    <dbReference type="OrthoDB" id="1650at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071034">
        <property type="term" value="P:CUT catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000467">
        <property type="term" value="P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071051">
        <property type="term" value="P:poly(A)-dependent snoRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034475">
        <property type="term" value="P:U4 snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22525">
        <property type="entry name" value="KH-I_Rrp4_eukar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05789">
        <property type="entry name" value="S1_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000038">
        <property type="entry name" value="Exosome complex component RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048565">
        <property type="entry name" value="S1_RRP4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321:SF4">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PNAS-3 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15985">
        <property type="entry name" value="KH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21266">
        <property type="entry name" value="S1_RRP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RRP4 S1" evidence="8">
        <location>
            <begin position="84"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="K Homology" evidence="7">
        <location>
            <begin position="178"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF15985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0593112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="310" mass="34243" checksum="BADF7F92F61B1C2F" modified="2022-10-12" version="1">MSGPHLDADHELRIAKAQRLLRDAAGGMHSRAFVNVGDVIPVDHEAGYLRGHGTQPVKEELLATVCGVVERVNKLVSVRPLRARYNAETGDVVVGRVTEVGGNRWKVDVNSRKDAELLLAAVNLPGGIQRRRTAIDELNMRDLYVENDLISAEVQSLHQDGSLHLHTRSLKYGKLRNGQLVRVAPYLIKRLKQHFHQLKDLGVDLILGCNGFIWISAASPGNKDNLPGSVATSASAVVGESPLQFEVRERICRLANSVRVLGALGLLISPDSIMQTYEASLLWEVPVKDMLSADFYVKLAEKEAEQRMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JE35</accession>
    <name>A0A8T0JE35_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G323000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JE35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044686">
        <property type="entry name" value="OFP17"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34042">
        <property type="entry name" value="TRANSCRIPTION REPRESSOR OFP17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34042:SF1">
        <property type="entry name" value="TRANSCRIPTION REPRESSOR OFP17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="220"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="356"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="369"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="481"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="656" mass="73127" checksum="BD930BF8BD98E895" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JE99</accession>
    <name>A0A8T0JE99_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PLATZ transcription factor family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G309100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JE99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006734">
        <property type="entry name" value="PLATZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065">
        <property type="entry name" value="PLATZ TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31065:SF35">
        <property type="entry name" value="PLATZ TRANSCRIPTION FACTOR FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04640">
        <property type="entry name" value="PLATZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="294" mass="32559" checksum="2BFDA15CD8174D00" modified="2022-10-12" version="1">MGSPGREVGSPDGRGRISESKMMSPTWLKPLLGTCFFASCPIHALVSHKSECNLFCLQCMGEGFCASCLPSHKDHHVVQIRRSSYHDVIRVSEIQKVLDITSVQTYIINSARVVFLNERPQLRPAKGVTNTCEGCQRSLLDTYRFCSLGCKLGGIEKLGHDHDLTFMPQPRQQPLMSIGNKMPMGEATTWSSEELSCPKKAPRSKKLAHLAASLTTSNYRLGRDDKENLDEASVSTVEPAHRARSSRKKGSINIDHHVIGITSRRRPLRCAPSRVANCTAKRRKGIPKRAPMGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G2L5</accession>
    <name>A0A8T0G2L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G014700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G2L5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385:SF0">
        <property type="entry name" value="RE51073P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21385">
        <property type="entry name" value="ZINC FINGER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035783882" description="C2H2-type domain-containing protein" evidence="3">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="4">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0553483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="280" mass="32882" checksum="0EE1CAF8C92EE762" modified="2022-10-12" version="1">MRRFWSWRIWVVVFLALALSSSRFIACAEKYRVSEERQRQLQEEKGRVHCSRSRSRTSRNIVSEYLMPFVESEKYTLPKSCRLHPDNDIYREQEGNIDELRPMQWQCRYCKKLFRSQVYLDMHFDNRHSENLDTSSNKCLADTCGALHCDYFDSLSSSKPKMQATCKPAVVEKNRHACEVLANTCFPAEKSPVAKKLNDFFKRQFCDAHTCKKKLKIYPRGSGIDRNRSLIYALSFFTIVVLALFYLVVYLHKRESGMLIKGLRRARSRPSFKGSKVQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G491</accession>
    <name>A0A8T0G491_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G001600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G491"/>
    <dbReference type="OrthoDB" id="10255247at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="402" mass="46315" checksum="D5D8412BD66183D4" modified="2022-10-12" version="1">MSEADARRNNLLKEKVVVLEFKINKLGISGRAYYEASQIKLRRNRYLIRSARTKNMLLHSALLLMEQKELASRKEASNLGGMRKQASDLREKFDQQRRIAIAKQLELAKQITDTRAAEIDCTDVLDPNTPSLIVIRWLDNRLETIFRRIKETQMLENQYESLLLPMRAERTLFTFQIENITNVIDLKNDQIGQLKMVEGDGVKSRDQARIELEEEGISKSIQNRIQIALRKIKKAMEVDSMREMYQQYMFQDKQIIYLEQIKAELIETLSKLRNEAPIPATHRRRSTSRLEQVGGLAEGVKATVRRMTVQVQRKNSYPLVLLVEGTKKLVEKIHEGTAKLDTMEASVVPEKLVLAETESKLVFLLKALDRKMKFLEDLEKKQKAELAQLEEAKSEAASSSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4L7</accession>
    <name>A0A8T0G4L7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein CHAPERONE-LIKE PROTEIN OF POR1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G044500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4L7"/>
    <dbReference type="OrthoDB" id="2014563at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021788">
        <property type="entry name" value="CPP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33372">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33372:SF14">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11833">
        <property type="entry name" value="CPP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="299" mass="33653" checksum="0D7AA1351AC459E8" modified="2022-10-12" version="1">MAALSDNLTCSLMRGNSNPLPKINGSTSFSVTYSFEPSMLYNVKRSKCSVHARAAKQSGQLSHSLRTDESLGTAVRKSWPRQQFSKRLVCSAMDASMGGSDPVFPRMNVRDPYKRLGINREAGEEEVREARSYLASQYSGDAKSMESIESAYDKIMMEKLREYQKLQSNPIKKKEAKPLPAWMQKIVNMYQVPNKDVILKRAAFYALLAIWTVVKPGDGGPAFQVLMSFLGCIYFLNDRIKKPFRSFFIGFGALVLGWVFSSFLVPVIPTKILPSSWTLELTSSLISYIFLWAGCTFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G546</accession>
    <name>A0A8T0G546_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G069100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G546"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="6027" checksum="569D8EF35E61E5A5" modified="2022-10-12" version="1">MLGRESQQTTLKNISRKSLTSTSVERFRKRMEDTWICMSCTISSRTPTLDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G651</accession>
    <name>A0A8T0G651_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G050100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G651"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37604">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37604:SF1">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="454"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="465"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="476" mass="52790" checksum="10D8091EB5CE4E99" modified="2022-10-12" version="1">MRLLGDNGAGYELAQRLEENAVWRAWLGERDYVVLQSYLQTPGTWSAFMQTVNPSVVALQLRVRALLFDKAVVSLHLDSAAASPPSALDNSFLQLHADSVYFTLEQDAEDWARLQVEKNPTFTSLQVKHGLDSSATFTRLNDAESGHAGINSRPSKASQSGQSVSSALISPRQLASRTHAKTGFNNAGNAIDHRSLGDLWYTQYLQRDLMNRMSRLARRTAQRGLPFGDQEAYLRTPIEMADYVSIQTNHRKRRPVFRIDGDSKQSLSGHERPIQGDDSALFMPENQYPGNCVPDNAVPARQNPSFDGFSAHGAFLDRLNHLRELSSGLFIRGKDRLGPAAEVSNQHFRKDAVGRGNSKEIGYKNGCSEEAAQQLAEQAVVRLVAAAGFEGLKQAPLQILADLLRCHVQKLGSALRRILDTYKMECSQAELLKMCIHGASGSKLEELMEYAKSTQPQKRRPAPVQMTQPTIQQVSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G711</accession>
    <name>A0A8T0G711_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G077900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G711"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035734067" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="7105" checksum="3737855B47334462" modified="2022-10-12" version="1">MQSTHHELSILFCLLLLSLLYIVWLFDDSSLESVCSCNIDLSNRDFDCFIMHWVTVYWST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7S1</accession>
    <name>A0A8T0G7S1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G049500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15999" checksum="C2DE3BA76FD78052" modified="2022-10-12" version="1">MDLFFLFGHLQMLLLPLKKLGRSDRSCQDKLVVCALFFHLSASVSLTWAVSPKRRPSKYQDQIRKVNKHVDFFFLFVSIERPHYGLLKGLVTWPIFIQLALQIPLRREEFAISMYSFWLLPAITFRLMSYHTFML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCB0</accession>
    <name>A0A8T0GCB0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G083200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCB0"/>
    <dbReference type="OrthoDB" id="676979at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051848">
        <property type="entry name" value="PGIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059:SF30">
        <property type="entry name" value="OS06G0587000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48059">
        <property type="entry name" value="POLYGALACTURONASE INHIBITOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035827061" description="Leucine-rich repeat-containing N-terminal plant-type domain-containing protein" evidence="4">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="5">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="273" mass="28493" checksum="CA460C3BEF3C4EDD" modified="2022-10-12" version="1">MGKLMLLPLLLALTLCVASACTPADQKALLAFKAQFNDPSGVFASWSPQDPIYPDCCGWKGVRCEFVAPGRVTSVSLQGGEGVATVKKGVTGAGNSLGDLTGLKFLVLTQIRFSFKHPVPPTLAKLKSLETLGLSGTQFTGTTLPSFLSTLTKLNDVTIEGNYFPDGIPASFGNMKALGLLSLPSNGMKTIGKSASSLTKLKNLNYFSVASNAITGRIPAWVGLLTPVKTTKDVYLQENKLTGPIPKSLSGLAVNSFRPGNPGLCGAPLAACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCG6</accession>
    <name>A0A8T0GCG6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G189600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8603" checksum="1B323221D59E27D5" modified="2022-10-12" version="1">MSKILASSILKWSPSQAFTITIWWGMLDFVMLNTRQYMCLSTCQMVRWINGFLRMLGKPTRTGLYREHLPRSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE94</accession>
    <name>A0A8T0GE94_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G175900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE94"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035819231" evidence="2">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="9101" checksum="14DBD9806B81CBFA" modified="2022-10-12" version="1">MMKLQITDPIWPEFDSPLLRLPMRHRLLLLLPLLLLLLIKFSRVEGDEDGKSASKQQRDRPQDRPWHERPCICRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEB8</accession>
    <name>A0A8T0GEB8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NmrA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G070700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEB8"/>
    <dbReference type="OrthoDB" id="419598at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051609">
        <property type="entry name" value="NmrA/Isoflavone_reductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706:SF1">
        <property type="entry name" value="CIPA-LIKE, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12460)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47706">
        <property type="entry name" value="NMRA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA-like" evidence="3">
        <location>
            <begin position="5"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0556674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="31992" checksum="C0EE2D968DB69D89" modified="2022-10-12" version="1">MATPIILAGATGNLGGRIARALVGKGADVRALVRRGTAPERAENLRKVGVTVTEVDLGNVPEVAAACAGGTCVVSALTGHRDVIVDGQTALLEAAVEAGVPRFIPSDFALDFMKMPAGFNRNLDLRREFHERLDKAPIAATSILNGGFMELLSQAPIILFRFRRVLYWSDADQLLDFTTIDNTAAFTAAAALDPSTPRTLRIAGDQLSAKDLVALAGDTTGEKFKLLRGGSLARLETMIRVTRTLFPQEGQVYPAWQGMQYLHNMFSGFAKLTPLDNDRYTDIRWTTAREMLSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF54</accession>
    <name>A0A8T0GF54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G145900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="28603" checksum="2807493E8E71E656" modified="2022-10-12" version="1">MYRQLTTCGIYRALDSDPSLNYCKFIEELLDGIEVGTVTKIILEGAKEKLRELEQIRLDDDHFPENYTEGFDVYVSGIAWILGILLNAGVAEELVTCLVPSETIPLYLLKHGADVRHEGLEMAKVVLQMYQEVVAGRLLLQTHDRVALIGIWHDLLEEYLPREEYIQATKALFSTLPFKDQFGFLETQGELFIKFIDPRSLAMLVKKNSSAMEGKLDSNEGNSRKEHGSSSRVRYGLERMKKRRRTVMWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFG3</accession>
    <name>A0A8T0GFG3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="9">4.2.1.76</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G009300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>UDP-alpha-D-glucose = UDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:21500"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:85329"/>
            <dbReference type="EC" id="4.2.1.76"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">In the N-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.76" evidence="9"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFG3"/>
    <dbReference type="OrthoDB" id="16464at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050377">
        <property type="term" value="F:UDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010280">
        <property type="term" value="F:UDP-L-rhamnose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010253">
        <property type="term" value="P:UDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000236">
        <property type="entry name" value="Bifunctional dTDP-4-dehydrorhamnose 3,5-epimerase/dTDP-4-dehydrorhamnose reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000304">
        <property type="entry name" value="UDP-glucose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43000">
        <property type="entry name" value="DTDP-D-GLUCOSE 4,6-DEHYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="11">
        <location>
            <begin position="103"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="RmlD-like substrate binding" evidence="10">
        <location>
            <begin position="491"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00050778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00067046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0558166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="777" mass="86164" checksum="159B684D395D4F87" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHV7</accession>
    <name>A0A8T0GHV7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transporter CorA-like family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G067600</name>
        <name evidence="4" type="ORF">KC19_10G067900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.340">
        <property type="entry name" value="Magnesium transport protein CorA, transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46950">
        <property type="entry name" value="MAGNESIUM TRANSPORTER CORA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46950:SF2">
        <property type="entry name" value="MAGNESIUM TRANSPORTER CORA-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="468"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="501"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="567"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="597" mass="66690" checksum="F32954E49035E2EC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ19</accession>
    <name>A0A8T0GJ19_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G036500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ19"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18773">
        <property type="entry name" value="PDC1_HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051173">
        <property type="entry name" value="Ca_channel_alpha-2/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166:SF37">
        <property type="entry name" value="STOLID, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="560"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="608" mass="65610" checksum="AFB5BE550D15BCAB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKK4</accession>
    <name>A0A8T0GKK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G078900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKK4"/>
    <dbReference type="OrthoDB" id="193931at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12195">
        <property type="entry name" value="CIPK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14663">
        <property type="entry name" value="STKc_SnRK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000279">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000096">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000002">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018451">
        <property type="entry name" value="NAF/FISL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004041">
        <property type="entry name" value="NAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF32">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE CHK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03822">
        <property type="entry name" value="NAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50816">
        <property type="entry name" value="NAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="9"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="NAF" evidence="14">
        <location>
            <begin position="305"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0559095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="453" mass="51391" checksum="18C56E1F44ECF806" modified="2022-10-12" version="1">MVMRKVGKYEVGRTIGEGTFAKVKFAQNTETGESVAVKVLDRQTVVKHKMVEQIKREISVMKLVRHPNVVCLHEVLASRYKIYIILEFVTGGELFDKIVHNGRLNENDSRKYFQQLMDGVNYCHSKGVSHRDLKPENLLLDSLGNLKISDFGLSALPQQVREDGLLHTTCGTPNYVAPEVLNDKGYDGAVADIWSCGVILFVLMAGFLPFDEVDLTTLYGKIREADFTCPPWFSSGAVSLISKILDPNPRTRIRMEGIRNDEWFKKNYVPVRMYDDEDINLDDVEAAFDDTKEQFVKEQKEVKDEGPSLMNAFELISLSQGLNLSALFDRRQDHVKRQTRFTSIRPAREIIMRMESTAKSMGFGVETRNYKMRLEAVGECRIAQHLAVAIEVFEVAPSLFMIEVRKAAGDTLEYHKFYKSFCAQLKDIIWKSAVDTSPVKPDQPSSPNAVNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM62</accession>
    <name>A0A8T0GM62_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G095800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052733">
        <property type="entry name" value="Chloroplast_QOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013:SF1">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35418" checksum="EA6CEAEF31BFA083" modified="2022-10-12" version="1">MAKTMLAAQYSKYHGGPSALEYVEVPVPTPKEGDILVKVEASSVNIVDWRIQDGLLKHILPRKFPHIPGTDISGEVVSVGPGVVGFTPGDKIISWIDLLRGGGFAEFALAPVTSTVKRPPTITAVEAASLPVAAMTALQCAINLVGLKLDGSGPKLNILITAASGGVGIFWTQIAKMAGCFVTATCGVRNMELIRSLGADEILDYKTPDGARYRSPTGKKYDVVVHLAPYQPLEAFKAQLTKQGKVIDMTPTLKTVLRNWYNKITLSKQSFLPFVLDAGNTTFLQMVTDLVEEGKLKVIVDSTFPLTKARDAWARSIEGHSTGKIVLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GML5</accession>
    <name>A0A8T0GML5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G166200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GML5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035789351" evidence="1">
        <location>
            <begin position="36"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="16362" checksum="970ABCEEC7FA6D40" modified="2022-10-12" version="1">MATCGSRLAATQQPALLLVLAVCMLATACAPGAHAQLLPPIGALPIANLTIVNSLSASLVAQLAGSEQSVTVAPGEEGVLQVGVPAVVENINLPIVFTYQDTEYSASGNTISKLVVLTNTVSVNVSTPCVNGQSPGLQANTTADSLVLGPIQLNSECALPTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNI4</accession>
    <name>A0A8T0GNI4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peroxidase</fullName>
            <ecNumber evidence="14">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_10G095400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 14">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="11 14">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 14">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="11 14">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="14"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNI4"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF80">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="8 13" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 14" id="KW-0349">Heme</keyword>
    <keyword evidence="14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="7 11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="5 11 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0964">Secreted</keyword>
    <keyword evidence="14" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036514609" description="Peroxidase" evidence="14">
        <location>
            <begin position="28"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="15">
        <location>
            <begin position="30"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="12">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="40"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="127"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="13">
        <location>
            <begin position="205"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0559308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="37946" checksum="EBE33B168E5A4E3B" modified="2022-10-12" version="1">MANSRVGALVSVVVLVWAMSSLNMAEANYNLSADFYAKSCPQYEQIIYSYVNKLYNSPKNNTVISMIRWAFHDFVNGADASFLLRSDNFPSNTSEKDSISQVGMRNSKYVNDIKVVVDSYCPGVISCADTLAVAGAAAVQIMGGPTIPLKVGRRDSRISLKSSADLIPRSNATVDQLLAFFTPLGLTTAEAVAMMGGHSVGRAHCVSFWKRLYPTADPHLTATFAAKLYDRCPKIQPTPGNPNPLNVTNPIHYTYIRNDPYSPLTMDNHYYQELLKRHGVMTVDDNLIWDNRTLPYVQLYAQDANVWKKTFMGAYQKLSEFKVLTGTQGEIRKKCTLLNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ88</accession>
    <name>A0A8T0GQ88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Purple acid phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_9G043300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a phosphate monoester + H2O = an alcohol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:67140"/>
            <dbReference type="EC" id="3.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.2" evidence="4"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07378">
        <property type="entry name" value="MPP_ACP5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024927">
        <property type="entry name" value="Acid_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051558">
        <property type="entry name" value="Metallophosphoesterase_PAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10161:SF14">
        <property type="entry name" value="TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000898">
        <property type="entry name" value="Acid_Ptase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="6">
        <location>
            <begin position="82"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000898-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0561180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="376" mass="42064" checksum="169204F6B391CD66" modified="2022-10-12" version="1">MAILGTKPVSDEEVGLLASEHSEEVEDQGTSTLRPATLVAAVVTIFLMSGCLISLYTYSQSDHDSSEEYSLESLTKPKYPLNFLVVGDWGREGAYNQTLVAKQMGKVGRHLGIKFVISVGDNFYQAGLKGPQDPKFKNSFSKVYTAESLQTQWLAVLGNHDYLGDALLQIGDGLTRKDKRWFCDRFYQLKYPLCGSHNLGHCEKFVELFFIDTTPFVDKYWDAEQARTFDWRGIGPRQEYLDSQLKNLSLALESSTATWKIVVGHHTIRSLGRHGETPELVKSVLPILESHNVDVYINGHDHCLEHIKREDSAVHFVTSGAGSKSFQGLREGTTEEGLQFGYDGQGFISVSMAAQVLRIDFHDALGNNLYELNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRE6</accession>
    <name>A0A8T0GRE6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G020700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05471">
        <property type="entry name" value="pepsin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034164">
        <property type="entry name" value="Pepsin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683:SF316">
        <property type="entry name" value="ASPARTYL PROTEASE APCB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683">
        <property type="entry name" value="ASPARTYL PROTEASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase A1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="277" mass="30261" checksum="633FFBE804652085" modified="2022-10-12" version="1">MKLGDPPKPFYLHIDTGSGQTWVLCANGETLSIISSLGPNGLLVTEEESVVACIGPTESLCRAHTSDPEHNMRCEEEDDYACFFSIMYADSSVYLGVVVNESMTLSMQDASEKRVFTLFGCVLEKHSRVEKLPLLTDGVVGLGRCEGSLVDQLWTSNVIQKKILGVCLAKELRQRSSGPLPAGRVGFISLGMDFSSKFDSQNLVWSKLAGPEKDCMLAAKLLFVIVGNRKIAIVLESDHSNNAGLTMGFDTGSEMSYFRQDVYDQLMKSGSVGDLHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUD9</accession>
    <name>A0A8T0GUD9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G019700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUD9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000981">
        <property type="term" value="F:DNA-binding transcription factor activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045843">
        <property type="entry name" value="IND-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16223:SF125">
        <property type="entry name" value="OS08G0506700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16223">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH83-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="406"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="66"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="453"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="80"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="90"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="106"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="299"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="482" mass="51883" checksum="4E9571664243A8D5" modified="2022-10-12" version="1">MLSVEDLRSFTTPGNGPITGMGSLDEEISAMLQSSHSTFSQASLAEVMAPDVFSSSFTSHASPYPRALPASNPHSGGLARTSSMSSAGLPNNSRPRPHPNSRISNQRPQNLSQKQWAPMTGDEKWMLDAKGEVLDMHSASNSPFSTGFESGFGMPMMNPPAPAAPPPSGGLHRYHSAPSAFLQALADEAFSQIPPPPPNANMFSEGGLTPITEVMDVERMGSGNSLNEFEQFLSPDSDFSRRAAMSALQAKADNAETYSNLFPPAKSTGLLRQKSLPVPQQNSIVPKQDPMEEHHSEDSISGTSEDNSLVSGFIVSGDALTSWPTSPGTPGSKRPRGSFPAWESETSSGGSAENPKSYRLNNNPNGLIRHMSLPTSTDPMEPPTPNPSSGDELNLVQMRARAKRGCATHPRSIAERVRRTRISERMKKLQDLVPNMEKTTNTSDMLDETVDYVKSLQLKVSELQETIVQLKAAAAAQNIKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUM2</accession>
    <name>A0A8T0GUM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G030800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="entry name" value="Serralysin-like metalloprotease, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="301"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="604" mass="67279" checksum="480A5E18B75D8951" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVC9</accession>
    <name>A0A8T0GVC9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cleavage and polyadenylation specificity factor subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G175500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000402">
        <property type="entry name" value="Cleavage and polyadenylation specificity factor subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018846">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10433">
        <property type="entry name" value="Beta-prop_RSE1_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 first beta-propeller" evidence="4">
        <location>
            <begin position="113"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="5">
        <location>
            <begin position="582"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="3">
        <location>
            <begin position="1101"/>
            <end position="1423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0562843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1459" mass="159821" checksum="2D6677906532B37D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWA6</accession>
    <name>A0A8T0GWA6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G078400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWA6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47186:SF34">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN RGA2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47186">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="103"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="3">
        <location>
            <begin position="305"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0564041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="574" mass="63999" checksum="9742E91DA297FF23" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWQ4</accession>
    <name>A0A8T0GWQ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G091700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWQ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="6051" checksum="48E4D725C6CA6CDC" modified="2022-10-12" version="1">MPIEREISFNQLLLQCLRLRVGLQENQFIVRFLRTVASMQSRICCVETNPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXM3</accession>
    <name>A0A8T0GXM3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G190500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0563019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXM3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="10875" checksum="BC85DAEA16314FFC" modified="2022-10-12" version="1">MSEQETKFGPFTSEFQILGSDDVPGMSQGLVGDGGRERRTWEYVGGMGWRMLGGQEGRLRWAVGTCNQSSTQVTTHERERERERIYTSGHCTHLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYG2</accession>
    <name>A0A8T0GYG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome c oxidase subunit Vb</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G081300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytochrome c oxidase subunit 5B (TC 3.D.4.11) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005740">
        <property type="term" value="C:mitochondrial envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045277">
        <property type="term" value="C:respiratory chain complex IV"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006123">
        <property type="term" value="P:mitochondrial electron transport, cytochrome c to oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00924">
        <property type="entry name" value="Cyt_c_Oxidase_Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.11.10:FF:000002">
        <property type="entry name" value="Cytochrome c oxidase subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.11.10">
        <property type="entry name" value="Cytochrome c oxidase, subunit Vb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002124">
        <property type="entry name" value="Cyt_c_oxidase_su5b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036972">
        <property type="entry name" value="Cyt_c_oxidase_su5b_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122:SF0">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10122">
        <property type="entry name" value="CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01215">
        <property type="entry name" value="COX5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51359">
        <property type="entry name" value="COX5B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00061018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602124-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0564080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="147" mass="16368" checksum="BC0CE466D348A061" modified="2022-10-12" version="1">MLRTAGRTLSRALRTSHRTPPPCSAACSQRWFNATGFHRSGHSGELDEFGIATGAEREELEWQKQGKRRFDLEPPRGPFGTKEAPAIVESHYDVRIVGCSGGVGEDEHDVTWFHLEKDQTHECPVCTQVFELKVIGPGGQPGHDEHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZE0</accession>
    <name>A0A8T0GZE0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G006900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZE0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="14694" checksum="CD28F1033A2EA8D5" modified="2022-10-12" version="1" fragment="single">MWTCGTPSCTNCCHLLPLDHLLPNTGMNSTTMSISCYKSAFMLDSHQISITTASSILVNNTPACKSYRAPISCQYWSSCVRCNINALHQHQNPQRSHQEYPQYLEISSVHNDKVLQKGPRCPKSSNLILHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4Z8</accession>
    <name>A0A8T0H4Z8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hint domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G174400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4Z8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016540">
        <property type="term" value="P:protein autoprocessing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00081">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.16.10">
        <property type="entry name" value="Hedgehog/Intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001767">
        <property type="entry name" value="Hedgehog_Hint"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050387">
        <property type="entry name" value="Hedgehog_Signaling"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003587">
        <property type="entry name" value="Hint_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889">
        <property type="entry name" value="HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11889:SF31">
        <property type="entry name" value="PROTEIN HEDGEHOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01079">
        <property type="entry name" value="Hint"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00306">
        <property type="entry name" value="HintN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="Hedgehog/intein (Hint) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035864043" description="Hint domain-containing protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Hint" evidence="3">
        <location>
            <begin position="230"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0565218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="477" mass="49660" checksum="EF1119C1B0AA9C65" modified="2022-10-12" version="1">MSNMALRMMPLLLVFLVLTHQAGAQLTISVTTFPPPKGDGTPNTFIGTGSQFAASLLGSSTPALMWGVVPSSDVNAVCTQIVNTGTLSFSATLTASSGATETLQQTITNVGGCLAAADGSGTQAVMVDSNGRQSAVVCPNNAGATGCGVFLAGPDVTALYNQGSARRRLLARMLLQDDCKSGAAQGALTGVATVMDACQPFIGPLYPFCAVGVILVATAGGAAVGCAEANGCFPGDATVILAGGEVKRMSSLALGDKVAVRRHDGGLDYEDIYAFGHKDASAAAKYVHLSLKPVGANMSDPALESTTLELTPLHFTVISSGSEISYKRARDVRVGDMMWAQASKHAELSLYLVTDISTVVKQGLYNPYTLGGTIIVNGVVASAHSEWFLDATFDALGVTHWLPNAYQMVLAPVRLAYYAMNKQAYLDLYHRLDATLDVAQFGTKYAGPLFTAAAGLVSTIIVSALIIYHSHCSVNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H761</accession>
    <name>A0A8T0H761_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G070800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H761"/>
    <dbReference type="OrthoDB" id="1669448at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36078">
        <property type="entry name" value="BNACNNG21220D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36078:SF2">
        <property type="entry name" value="OS09G0473966 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12689" checksum="67539F3A7552EBE9" modified="2022-10-12" version="1">MMASSDAMEAAAYAAKYRKYERDYLRRINHLYFSGKAPDNGDMFEDVSTVDDFVIKESKEAPLRKFLASSALVNRDPGAPKVESMDIDPSLPSTSNKKPQRSTPDGSRKPARGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8R5</accession>
    <name>A0A8T0H8R5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G162200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035846679" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6246" checksum="7061AFF50C48A8B6" modified="2022-10-12" version="1">MWGSVVHRKRPFLFFLHNLQLLLKVADTKICNSSSDKNVENQNGDAGTYIKVIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA17</accession>
    <name>A0A8T0HA17_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-fructofuranosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G104400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18624">
        <property type="entry name" value="GH32_Fruct1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.115.10.20:FF:000001">
        <property type="entry name" value="Beta-fructofuranosidase, insoluble isoenzyme CWINV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050551">
        <property type="entry name" value="Fructan_Metab_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31953">
        <property type="entry name" value="BETA-FRUCTOFURANOSIDASE, INSOLUBLE ISOENZYME CWINV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="7">
        <location>
            <begin position="103"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="8">
        <location>
            <begin position="424"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0567019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="626" mass="70802" checksum="00AB1B192A9C85CB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA30</accession>
    <name>A0A8T0HA30_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G187700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA30"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="13394" checksum="6D705374078AAD1F" modified="2022-10-12" version="1">MRCVICHPTSVSSPSSSRTTRSRKGVVNYNHNHGSTSLKKHVDSAHSELYERYVKEMAEKQALETPTSARTKNKKRKSIQASQIVDFFGSKEAYRKLDLPQVNFNILFHVTSHFSPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBG2</accession>
    <name>A0A8T0HBG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G156300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBG2"/>
    <dbReference type="OrthoDB" id="1908917at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="422" mass="46795" checksum="5B530CC08ABC32D6" modified="2022-10-12" version="1">MGDKTFADKELAGEMGSFKEPGVRLKQVEGEGASSFADGDLEKALFLGMQQLALAKLCYEEPNTKDKEVMMAQAHYNLSVIYYEMGLGDQSLYHAQKALERVDPRKTGEGENNNFTVSCMMAIARAMIQRSDPKCVNFLQRALVVNHELNGPDHDSNFRIHEGFGDFYVLLGDSRALYKATTAKKDTSVDVNAKKKQEPDDYEKAMDEYATAYSKIAGGGKATAFYGGLGSTKDARMGDMFGHAAKTRSKMGNDNEAAVIYEKAVACLESASKPNKAKIAQMCYELGATYHKAKQYSYSKNALDRGLGYCSGIARPDGESDPILMLLKKQQAITMYDGNEVENARKTFEELLALQKKEYGGNSVIVAETLKYLGDVHVALKNKPLASKFYNRALKILRKRLGSIDQTVKQLEQYIKQLNLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEN9</accession>
    <name>A0A8T0HEN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_6G150200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Activates SnRK1.1/KIN10 and SnRK1.2/KIN11 by phosphorylation of their activation-loop 'Thr-198' and 'Thr-176', respectively. Required for the regulation by SnRK1 kinases of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Associates with the SNF1-related protein kinase (SnRK) complex. Interacts with AL1, a geminivirus (TGMV) protein essential for viral replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000747">
        <property type="entry name" value="Serine/threonine-protein kinase GRIK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000206">
        <property type="entry name" value="Serine/threonine-protein kinase Ssp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF39">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GRIK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="128"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0570276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="431" mass="48245" checksum="4A90DB38D5650BB9" modified="2022-10-12" version="1">METQCTCCGFFWFSKKRDHGKSSSKPIVKRISKEHLLAYTSSNEERNASRVGRQAAKSLNYYNPPPNEAENGSQEDGGKQTFEELRAAMRRSNHGLPLVLPLLRAGVKETSHEFRSQDADGNKMVNEYVWKGKIGTGSYGKVVLYQSQKDEKLYAIKIFHKSRLCKLRVSPTETAMTDVLREVAIMKRLDHPNIVKLHEIIDDPQSDNMYLVLEFMEHNRIFEGCGPLGGIGEALAQKYFRDAAAGLSYLHGHNIVHGDIKPENLLLSGEGSIKICDFGVSRMFEGENDELRRSPGTPVYTAPECCSGSYYRGRPADVWALGCTLYCMVFGRYPFVGDGTFPSIYDEIVNQPLFIPEGTNPDLADLLRGLLCKDVRNRMPLAAVVTHPWLSRSFGQVQANGYKTTYVLQHPFPAGGRPSFENGSVELESMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFB7</accession>
    <name>A0A8T0HFB7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G155800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFB7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="11159" checksum="DB16DDFD2EF5C381" modified="2022-10-12" version="1">MYQHLHANYNQVLDKYGYAHKALASFKTQRIRKDTSDPLGLKDETMPKEHNLADDTSDLTFQEREFLRNKERVEQQEDLKQKTQPYYILRRAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG95</accession>
    <name>A0A8T0HG95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G095700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="201" mass="24763" checksum="6CC2ABB0DF66C4DD" modified="2022-10-12" version="1" fragment="single">LPLLYLSFLSFNSLSFSFLFHFFLSFILFFLSFYFLVPFIFSFILFSLSFFFLFHFIFSFILFCLSFYSLFHFIVSFILFCLSFFFLFHFIFSFILFSLSFSCLLHYNFSFILFSFSFYFLFHFILSFILFSLSFYCLIHFIFSFILFSHSFYFVFHFIFSFILFSLSFYFVFHFILSFIFLVAFILFSTLIFIFAFFPFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI67</accession>
    <name>A0A8T0HI67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G180700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI67"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045277">
        <property type="entry name" value="DRE1A-I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31839:SF2">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 1D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="9">
        <location>
            <begin position="41"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0570687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="19193" checksum="90CC62A85F5326C1" modified="2022-10-12" version="1">MSSPFHDAEFHAHGSNIPSGLPRDQVQAETLEQDDDSTGSREGGVRFRENLGKYVVEYRPPRFKWKLWMGTYRTVEEARRACDCARFYAGQNNDGYYYRDSPALFGELGPLAQPFTSVSKDVKDKAFNVQLKKRAKQVIKKVRDAEGAGQSVHSTVSQFSGTQEMQPPLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIS5</accession>
    <name>A0A8T0HIS5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G187700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3970.10">
        <property type="entry name" value="BSD domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005607">
        <property type="entry name" value="BSD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035925">
        <property type="entry name" value="BSD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051494">
        <property type="entry name" value="BSD_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019:SF5">
        <property type="entry name" value="BSD DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16019">
        <property type="entry name" value="SYNAPSE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03909">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00751">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140383">
        <property type="entry name" value="BSD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50858">
        <property type="entry name" value="BSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BSD" evidence="2">
        <location>
            <begin position="214"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="284"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="353"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="420"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="441"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="453" mass="49666" checksum="CAF9DAB136B84E48" modified="2022-10-12" version="1">MMGRNPIGGFFSGGLFGSTSASSSPRAAESHEEHDGDVDDVEQESPRESQSSGWNFGGFMKTIAEKSNISANLSGVLQTYQQDLKEFGIGLKKETEVITGATAHVVKDLPTSLETGATVAQESLETVGQTLEEFGSSVWRGTSEIFAHVKEAVLTVDEDTVGSSSLESHSSLGDSSNSLSNAKYSRYEAQVNAMQRDSGTYCDEPEDEKDFAAWAADFNLDERTEEIQEILSTNAFMQELQNQIVPVVVEYGTFWSRYFYRLNKLQQIENARVNLVKRAIDAEEEEDLSWDVDEEKEEEDEKEAEEVHEPVAPSEVVAEDAKPAEALTSTRSIDVPVVASTEETHDEEEAKSEGSAGSEWLVVSEGKGSGSSEPKTSPSSPMSDRHETESSVPTKSEEHEVDEAELDQLGDLSIDDDTEVLVKEKKGEEKAATPKSLDTTAGEENEEDWGEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNP0</accession>
    <name>A0A8T0HNP0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG093400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="10303" checksum="D6807BA5550FCC9D" modified="2022-10-12" version="1">MARDCINSLYNFVELQLIKVTDKSWCYTKATTVALVVLNRPRFSKKGSGLKAGSMRVDSAKALAVRLSLVLNPTLKGQVFGLGWTISFSRCYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRG6</accession>
    <name>A0A8T0HRG6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG187700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8838" checksum="D0387D285C4CFA67" modified="2022-10-12" version="1">MLEQSQSHCGSSCLGKASRKAMSVPPLEEMDCLVLLLVTLDRLAVLVCLRTNSVCPKGRQRESSWLYEASLIKKTWKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRU4</accession>
    <name>A0A8T0HRU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG162500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10012" checksum="E5AC54BC4DAEDE5D" modified="2022-10-12" version="1">MIEATYLGAVEADTVFHKPTHIIVYHKDGQEIPYKNILRSLGGQPEQDMVKFSEFLCSGGDKIKIVYQNSLSDSLKANTALPVAEYEVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS50</accession>
    <name>A0A8T0HS50_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_VG191300</name>
        <name evidence="14" type="ORF">KC19_VG191400</name>
    </gene>
    <organism evidence="13 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Alfin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15613">
        <property type="entry name" value="PHD_AL_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000306">
        <property type="entry name" value="PHD finger alfin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045104">
        <property type="entry name" value="Alfin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021998">
        <property type="entry name" value="Alfin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044104">
        <property type="entry name" value="PHD_AL_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12321">
        <property type="entry name" value="CPG BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12321:SF98">
        <property type="entry name" value="PHD FINGER PROTEIN ALFIN-LIKE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12165">
        <property type="entry name" value="Alfin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="210"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="146"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="194"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0573589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0573590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="30268" checksum="B68CB1698539AE3A" modified="2022-10-12" version="1">MEGASVSTNPRSVDDVFKDYRGRRAGMLKALTSEVEEFYRQCDPEKENLCLYGFPEETWEVNLPADEVPPELPEPALGINFARDGMQRKDWLSLVAVHSDAWLLAVAFYYGARFDKNERKRLFSLINELPTVFDVVTGKKLVKEKASANNNNSNSNNNNNNNNNNNNNGNRAKPAAKMQRVTETVKVKAAPPREEEEDTLEDEDEEEHGDTFCGSCGGSYTADEFWIGCDICEKWYHGKCVKITPARAEHIKQYKCPACSNKRAPSFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS62</accession>
    <name>A0A8T0HS62_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG195800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="18576" checksum="72F1A502A8C8305E" modified="2022-10-12" version="1">MTGMAGVEPTRSWTGGDTIPMTPNTMLQNFTNKMPVGAEVSTDISASIRSGAAEHSLHSSVNTISQYRGPDHRPLPCSANPTLEHVISSPTCTNNDGVSTRRMTSTAVAEPTTRAPRPRFEYGLLPRISNSPLAANRLCIVLGKTKKRNPKVGLGLRNKIQHMQLQPKLYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSG9</accession>
    <name>A0A8T0HSG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ACT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG200500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040217">
        <property type="entry name" value="ACR1-12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056816">
        <property type="entry name" value="ACR2/9/10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056805">
        <property type="entry name" value="ACT_ACR9/10_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31096">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN ACR4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31096:SF65">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN ACR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24914">
        <property type="entry name" value="ACR10_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24931">
        <property type="entry name" value="ACT_ACR9_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24926">
        <property type="entry name" value="ACT_ACR9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ACT" evidence="2">
        <location>
            <begin position="114"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="418" mass="47669" checksum="7E1BCBFC1DB0D066" modified="2022-10-12" version="1">MRAMRAYGDEFVVVSVGAQPEDLTEITINCPDKVGLGCDISRIVFEFGLSIARGDLATDGRWCFVALWVIARASQMPTRWQLLKQRLEDVCPSAIPSLLPHPTPQVHLSQRVMLLQVCSSDRTGLLNDVAQKLWELEFTIHKVKVSTSPEEKSVNFFFITDNKNIVPWKKRREEVIGQVKELLGPNCSHCEMRLASPEEKGLDILPAPAWVTKDLFFDESTPCDGGSWRVQHSRLVEIVVKHDIQSPLHTLLQVTCKRRKGLLYDCLRCVKDLRFQVAHMRIASLENGNSEISVFFLDPKGQRITDTVEQKEICACVREAVEHPLRIKFVTRGDDTELFVSTPIETCGRGRPRVVYDVTLALRELDICIFLADIGRHLVNDQQWEVYRFLLSEKEDFSLTDPKNRNVITDRVQEMLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSR2</accession>
    <name>A0A8T0HSR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG217500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="141" mass="14580" checksum="476CC2417A3C7894" modified="2022-10-12" version="1" fragment="single">VTYQQLADPFHVHHSRGPHPHPSLLQRASSSHSPPLQPSSSAPSQPATATPPPAREDHYSSAAVAPPTPATPTSQLPHSSPRPSATNAALAPAPKSATLTPPHPSPQEIHAAPARPIAPPPPLPSPSGVREWGAGVHHFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTU6</accession>
    <name>A0A8T0HTU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG244600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14215" checksum="D954CAB83245FC9F" modified="2022-10-12" version="1">MYSLKDLPNVTLIGRTEAMAPLVCSLEVAGTQSLSADRLRVKVSSTSPWNNSFARQHKEISVPLLSALNHHGRRTTTSHNSRKLSITRCKSKWKTGFEEDDICEMAHNHLLMRSVCPLLEEETRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVL2</accession>
    <name>A0A8T0HVL2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG286900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9204" checksum="0B7AD26D3117B21D" modified="2022-10-12" version="1">MTAMVASSSNLISALSLQHKSSAQLVLILVEIQWCLDTSMVSTYLGDFNSAASFNAMYCLLALGGSMMCILYFAVTNCFTFLSVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2024-11-27" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZT1</accession>
    <name>A0A8T0HZT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G069200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027728">
        <property type="entry name" value="Topless_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44083:SF45">
        <property type="entry name" value="TOPLESS-RELATED PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44083">
        <property type="entry name" value="TOPLESS-RELATED PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="53"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1456" mass="165659" checksum="245396CC8D292C02" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0C1</accession>
    <name>A0A8T0I0C1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G055200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0C1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11482" checksum="C57DFC17497F5395" modified="2022-10-12" version="1">MNYDQLYYLVYHCLIISFNSNTISSSESENLVFKQGARRFSLLAIVQLILCYEFCVFIRYFASARGPDGANFEFIVMLCMCLLMHSHLLDLCQGNILNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0F7</accession>
    <name>A0A8T0I0F7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent RNA helicase</fullName>
            <ecNumber evidence="5">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_5G094500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNA helicase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="5">The Q motif is unique to and characteristic of the DEAD box family of RNA helicases and controls ATP binding and hydrolysis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="5"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0F7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17956">
        <property type="entry name" value="DEADc_DDX51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031">
        <property type="entry name" value="RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="86"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="349"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="513"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="521"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0576626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="537" mass="59594" checksum="75DD6B525BF2E3AC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1C6</accession>
    <name>A0A8T0I1C6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G095000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Na(+)(in) + H(+)(out) = Na(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1C6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF197">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="119"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="267"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="312"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="350"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="424"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="14">
        <location>
            <begin position="46"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0576631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="567" mass="62992" checksum="B81762F74CD55B7F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1E4</accession>
    <name>A0A8T0I1E4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G142900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1E4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="423" mass="48021" checksum="43CED5DF64D73639" modified="2022-10-12" version="1">MLVIEVQLPQQEGRKKIEWNKNGDPTFEELKGRIQQCGVPDDWCVEVLRGNSFVSPDLQTHIHGPKITVRASPVLDLRVEEEHPDDIQWTRWMKTAFEKVISHVGRLYLVDTTKEEEVKDARGEGRCVGTVSLMDCHGECICALHCIYPAVENPERYKIYAAFPNYLRGCLSFEAKPRIMDEEVDVCVIEPVQPLKKPYLPTSYLDLATDVREDDIIYCFFFPRDPLKHVTPQVLQNLLMVEKKNPLRAAAARRPQDNPTIIAGTVCFSEWMQGVAAYERPPDCNGGILVSRSGRVKGIHVKAFTCGELRAKVNSENPEELRVARKLCRKMSTYAPTDGIPVFVPPHGLVRLLGLEGGCELLQAAIRQNKEKMKMNLPKQPKPPRSSRSIRSSRSTRSRCSTPHKCRTSNKRRRSIGKKVGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3P9</accession>
    <name>A0A8T0I3P9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G136000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3P9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="42131" checksum="A4D3BD2A71CAC49B" modified="2022-10-12" version="1">MNSATASPRTDAARASPRTNAARASPWTASNLVAPVPLKKVPKLKSIPNVVTPTKFREGKWLECGCPRSAANRAQKVDLTPRQHAHMAVLDESLLHYIFDRQAYLKINELAPQEPHLKQWMIDRCNEGRLFVAKPPTRPPSTEPWRYVSPPKLGRLEPGWRAWDPRDVALTFSPVNTVEEYNEHLETFFLWLNVPRAMKASMMETGEAWMLAAGQETDHLKVNNLRTSKVDRCFVTCDMEFFELLMAKWDRMSFFTRSIKCGEKMNYMKRLMDIRLDPHRSYNSTGTRVDPCKGLKVHGHQLCSTHGEWKLRRAVQSAPAPVNTFKLLSPREPPKTRARKLDEDSKPCRGSRWCSWAIVEEPPLCWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4F8</accession>
    <name>A0A8T0I4F8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_5G168500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the TOP6A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4F8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000228">
        <property type="term" value="C:nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042138">
        <property type="term" value="P:meiotic DNA double-strand break formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000706">
        <property type="term" value="P:meiotic DNA double-strand break processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00223">
        <property type="entry name" value="TOPRIM_TopoIIB_SPO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1360.10:FF:000003">
        <property type="entry name" value="DNA topoisomerase 6 subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013048">
        <property type="entry name" value="Meiotic_Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002815">
        <property type="entry name" value="Spo11/TopoVI_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013049">
        <property type="entry name" value="Spo11/TopoVI_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036078">
        <property type="entry name" value="Spo11/TopoVI_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034136">
        <property type="entry name" value="TOPRIM_Topo6A/Spo11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10848:SF3">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN SPO11-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21180">
        <property type="entry name" value="TOP6A-Spo11_Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04406">
        <property type="entry name" value="TP6A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01551">
        <property type="entry name" value="SPO11HOMOLOG"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01550">
        <property type="entry name" value="TOP6AFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56726">
        <property type="entry name" value="DNA topoisomerase IV, alpha subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52041">
        <property type="entry name" value="TOPO_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Spo11/DNA topoisomerase VI subunit A N-terminal" evidence="13">
        <location>
            <begin position="75"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="Topoisomerase 6 subunit A/Spo11 TOPRIM" evidence="14">
        <location>
            <begin position="184"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0577631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="361" mass="40330" checksum="30B0120758E040D7" modified="2022-10-12" version="1">MAGGTSGSADLLPHIQLFLRQVLHDLSNGDQVAVSIPVYKPREYPLETNKNCLTIFEETTKYEEISCNSKGGSQRLVAMLRVLQIAEGLLQQNRRATKRDIYYTDPALLKGRLDQSINDICSLFHCSRSSLNLVASSKGLVTGQLCYFEEGRLINCSKRNSTSTGLPVPVHMNEVSNISSGAEFILLVEKETVFQRLTNDKFCAKNRCILLTGKGYPDVATRSFLRRLVDELHLPVYGLMDGDPYGLDILSIYRFGSLTMAYDAEVLAVPTIRWLGIFLSDLGTYGLPESCLLHLSKQDVKKADALLSRSYLQYLAPVWWAKLAEFRHRGVKLEIEAVSAASFSLLADQYIPSKIRGQCYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I637</accession>
    <name>A0A8T0I637_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G187800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I637"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11883" checksum="888A1429846A99FD" modified="2022-10-12" version="1">MWARWEGGVVWRDLGLGLSGRAWCDRGEVWWRLGDWEGGGVARNLLSLLRHCSWFWGQTFGSWCDFCFPKCWWLRVVVDFGEYSSFESRGSVACELVERVAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6I3</accession>
    <name>A0A8T0I6I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Large ribosomal subunit protein uL6 alpha-beta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G207000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6I3"/>
    <dbReference type="OrthoDB" id="10252633at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000003">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.930.12:FF:000004">
        <property type="entry name" value="60S ribosomal protein L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="entry name" value="Ribosomal protein L6, alpha-beta domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_uL6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_uL6-like_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_uL6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002359">
        <property type="entry name" value="Ribosomal_uL6_CS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF16">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="60S/50S RIBOSOMAL PROTEIN L6/L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="Ribosomal protein L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00700">
        <property type="entry name" value="RIBOSOMAL_L6_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="13"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Large ribosomal subunit protein uL6 alpha-beta" evidence="4">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0578128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="189" mass="21536" checksum="1FFE885479A8D0D3" modified="2022-10-12" version="1">MKTILASQTMDLPEEVKVEIKAKQLRVSGPRGVLTRDFKHLNLDFQLQDDGRKLKVDAWFGTRKTMAAIRTAISHVNNLITGVTKGYRYKMRFVYAHFPINASIGADKDNIEIRNFLGEKKVRRVEMLQGVTVTRSEKVKDELILDGNDIELVSRSCALINQKCHVKKKDIRKFLDGIYVSDKGTIADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6Q2</accession>
    <name>A0A8T0I6Q2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G041400</name>
        <name evidence="3" type="ORF">KC19_4G041600</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6Q2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="401" mass="43076" checksum="F043BDDAFC8A10AC" modified="2022-10-12" version="1">MMCPVSVPFPSTTVASISLSSWWSTLSSLSFISFISFGSDSTPLEPAFVAAAPPPPIMFVLPPTPAAADAIQRSRPPASLLCLHLRQLLSAKHPLPLRNHIRLALESPHHNTSIAPTATVPHNHTSDIFPNHHPHPSRSTSPTLSVPHQTATNVSTVAVPRANRLVSKGSPGMSSHLPDEPHSPEKPTGGGSETSRHPRPPTATILRRSRDHPTTHPPHNHPNHLYTTTSTQPFATHECPHANPASPRDCRSTATADKSSGLALLLGPDCSLSWMFSAARMLSGPTNVAQTHSLLRSGISTLPHTSTSATPHSHHRGRGAGISIEDGTKSEEHSVLRIAPQVCSFPPAPNYGRTNSLRRRMPGHEREGNATFPHRATSRTAECASLRTRVTPYAAHMLPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I781</accession>
    <name>A0A8T0I781_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G011100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A22B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I781"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098554">
        <property type="term" value="C:cytoplasmic side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098553">
        <property type="term" value="C:lumenal side of endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042500">
        <property type="term" value="F:aspartic endopeptidase activity, intramembrane cleaving"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033619">
        <property type="term" value="P:membrane protein proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007369">
        <property type="entry name" value="Peptidase_A22B_SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12174:SF73">
        <property type="entry name" value="SIGNAL PEPTIDE PEPTIDASE DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04258">
        <property type="entry name" value="Peptidase_A22B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="336"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0578283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="513" mass="55565" checksum="FA57DA2B5F013864" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7R5</accession>
    <name>A0A8T0I7R5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">beta-galactosidase</fullName>
            <ecNumber evidence="3">3.2.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G108300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7R5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000021">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000115">
        <property type="entry name" value="Beta-galactosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026283">
        <property type="entry name" value="B-gal_1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048912">
        <property type="entry name" value="BetaGal1-like_ABD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048913">
        <property type="entry name" value="BetaGal_gal-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="BETA-GALACTOSIDASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21317">
        <property type="entry name" value="BetaGal_ABD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21467">
        <property type="entry name" value="BetaGal_gal-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006336">
        <property type="entry name" value="B-gal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035777434" description="beta-galactosidase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase 35 catalytic" evidence="11">
        <location>
            <begin position="37"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase 1-like first all-beta" evidence="12">
        <location>
            <begin position="410"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-galactosidase galactose-binding" evidence="13">
        <location>
            <begin position="574"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR006336-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF21317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF21467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0579584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="663" mass="73361" checksum="7628A32822F49915" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9E7</accession>
    <name>A0A8T0I9E7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G106400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Cold-regulated 413 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9E7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008892">
        <property type="entry name" value="COR413"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33596">
        <property type="entry name" value="COLD-REGULATED 413 PLASMA MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33596:SF23">
        <property type="entry name" value="COLD-REGULATED 413 PLASMA MEMBRANE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05562">
        <property type="entry name" value="WCOR413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="301" mass="33015" checksum="877EBA1934FD4B0B" modified="2022-10-12" version="1">MKCSNQEETNSAENNAGAAKDDVKERVGEVAEPGIRGAATQGNTRLEPDLDRSIFISSITYYYSLIFPHAPHSQIIPLSDHLHHLPHRFAASVPVFAAMVNPTYGIEMVSSQTLDQDWQAVGAALSQLGAHSVAALGLGYTWTGILQWLAVIAAIYLLVLDRTNWRTNLLTALLVPYLALQLPESIFGILRGNIGLWIAFIAVVIRLFFASQFPQTIHGDLELPAAFILLIVTAPSVLVNYRLSVWAEAICLIIGAYLLIQHINNAGGCRPAFSETRGVSHTIGIILLFVAPLWAIFHYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2024-11-27" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9Q6</accession>
    <name>A0A8T0I9Q6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DnaJ homologue subfamily C GRV2/DNAJC13 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G117600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007032">
        <property type="term" value="P:endosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006898">
        <property type="term" value="P:receptor-mediated endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000641">
        <property type="term" value="P:regulation of early endosome to late endosome transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044978">
        <property type="entry name" value="GRV2/DNAJC13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045802">
        <property type="entry name" value="GRV2/DNAJC13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36983">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36983:SF3">
        <property type="entry name" value="DNAJ HOMOLOGUE SUBFAMILY C GRV2_DNAJC13 N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19432">
        <property type="entry name" value="RME-8_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaJ homologue subfamily C GRV2/DNAJC13 N-terminal" evidence="1">
        <location>
            <begin position="22"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2255" mass="253053" checksum="B951A35E21EA7B60" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAG2</accession>
    <name>A0A8T0IAG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">IF140 C-terminal TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G137200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056156">
        <property type="entry name" value="TPR_IF140_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722">
        <property type="entry name" value="IFT140/172-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15722:SF7">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24760">
        <property type="entry name" value="TPR_IF140_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0966">Cell projection</keyword>
    <keyword evidence="4" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IF140 C-terminal TPR" evidence="6">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF24760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="16250" checksum="013D70B41CD3EFC2" modified="2022-10-12" version="1">MSEALKYLKKSNKFDKDEKVKSLQTRIAEMEHFGQIRRMAKTDPIGMVRACRELLAQLSRTKGSPQASLRVGDLYALLIEFYFRQGNSEQAYQLIEKMRSQKIPIGQFVDQNIVESICEALGMEAAEDNLSEGISEDIASLGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBL8</accession>
    <name>A0A8T0IBL8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G125700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBL8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16467">
        <property type="entry name" value="RING-H2_RNF6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000348">
        <property type="entry name" value="E3 ubiquitin-protein ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46225">
        <property type="entry name" value="C3H4 TYPE ZINC FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46225:SF19">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="277"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="375"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="334"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="423"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="41"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="186"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0579818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="452" mass="47701" checksum="9152791D99709BD4" modified="2022-10-12" version="1">MADRCEDLDLESQTSDTSPLLMDQQASVPQEHVVTIGPDTDSASVDSGTLFRSSSSPSVPQEGASTGETLSRSQSANSSLRGQPSFPSGASTPSARSANSHGRSARQRTSPLNSGLWITIELTITISQIIASIIVLSVSRDEHPEAPLEAWVIGYAAGCVATLPLLYWRYTHRYVRSREQNAVPQAASSPTTPPSGSGATSYRSTARDVVLNTPRHQGSDGHVSLDDDRIGVLVERFKIVLDCFFAIWFVVGNVWIFGGHTSSSEAPNLYRLCIVFLTFSCIGYAMPFILCATICCCLPCIIALLGFREDPNQTRGASADVISALPTYKFKAKGSKKTKGSKDGDESDSESGGEGGLVAPGTEKERQVSAEDAVCCICLGKYTDGAELRELPCTHHFHVECVDKWLKINASCPLCKHEVGGAANAGSGNAGEAVSGSSEGQEGAAVGSGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID76</accession>
    <name>A0A8T0ID76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G212300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="604" mass="67337" checksum="BB4B14CCB5204FEF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDJ6</accession>
    <name>A0A8T0IDJ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G222000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="32" mass="4046" checksum="13B69F5079F9EB91" modified="2022-10-12" version="1">MVVVMFWDHVVAVWVCSNEWRCVTWFRMMCFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDT1</accession>
    <name>A0A8T0IDT1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G223200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7356" checksum="62C44A1F507B3A7C" modified="2022-10-12" version="1">MCAVHTSVCVEVVKSKDWRLLRRLQRCSGAREGARSLSRYHSAILPPLPAWMLWVCVLPSLHGRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEP4</accession>
    <name>A0A8T0IEP4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G243300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044159">
        <property type="entry name" value="IQM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31250:SF27">
        <property type="entry name" value="IQ DOMAIN-CONTAINING PROTEIN IQM5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00612">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="362"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="398" mass="45171" checksum="1CACA27C481525DA" modified="2022-10-12" version="1">MAEEAEPLSPKTAAVRIQKSYRGYRARRKLADAAIMAKAFGWWNIVDSAVLQEHTQQYYAHSKSWKAIDHWKRLKRKASKVGKGLEKSKDKPLKLALQHWLEAIDARHRYGHNLRPYYLHWLQLETHEPFFYWLDVGDGRQIELEKCSRAKLQEQQINYLSPEQRKHFEVSIYKGKLFFKESGELVSTTESDSDDRWIFVMSPSGKLYVGKKERGTFQHSSFLAGGATTAAGRLSIHKGILQLMEAHSGHYRPSPENFEALVRILIESGADLSFAKVQLVSDDLREKKQGKKLAGEVREAIKEVSEEEHVSVKVENQSLVSVDSGLDETSYLVTNVTFPSDEPSAAKKLKKTKESTVGEALPSSQGFSRNSSLAALRPEERHEALQKYVMEPSPMVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IER9</accession>
    <name>A0A8T0IER9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">CAAX prenyl protease</fullName>
            <ecNumber evidence="15">3.4.24.84</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_4G215000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Proteolytically removes the C-terminal three residues of farnesylated proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 15">
            <text>Hydrolyzes the peptide bond -P2-(S-farnesyl or geranylgeranyl)C-P1'-P2'-P3'-COOH where P1' and P2' are amino acids with aliphatic side chains and P3' is any C-terminal residue.</text>
            <dbReference type="EC" id="3.4.24.84"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="14 15">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Endoplasmic reticulum membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12 15">Belongs to the peptidase M48A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.84" evidence="15"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IER9"/>
    <dbReference type="OrthoDB" id="360839at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.10:FF:000005">
        <property type="entry name" value="CAAX prenyl protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.10">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10120">
        <property type="entry name" value="CAAX PRENYL PROTEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 15" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 15" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 15" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 14 15" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="CAAX prenyl protease 1 N-terminal" evidence="17">
        <location>
            <begin position="36"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M48" evidence="16">
        <location>
            <begin position="224"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="13">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="371"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00044456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00060927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU366005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0580978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="48952" checksum="72D9C61C8B189DB3" modified="2022-10-12" version="1">MEVHGQAMASPFPYLEAVVGFMIVMYLFETYLDVRQHSALKLSSLPAPLKGVVSQEKFEKAQAYSLDKSRFHFVHAAVNIVEESAILLLGLLPLVWDKSGSLVGMLGLDEKSEILHTLSFLAVTTLWSQVLELPFSLYSTFVIEARHGFNKQTVWLFFRDMVMGLLLMVVVGPPIVAAIIVIVQKGGPYLALYLWGFMLLLSLVMMALYPVLIAPLFNKFTPLPEGPLRVKIEKLASKLDFPLKKLFVIDGSTRSSHSNAYMYGFYNSKRIVLYDTLIEQCKDEEEVVAVIAHELGHWKLSHTMYSFLAMQVLTLLQFGGYTLVRNSKDLFLSFGFTTQPVLIGLILFQHTIMPFHHLVSFALNLVSRAFEFQADAFARSLGYREPLRAGLIKLQEENLSAMNTDPWYSAYHYSHPPLVERLQALDEASKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEX8</accession>
    <name>A0A8T0IEX8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mediator complex subunit Med12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G051100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Mediator complex subunit 12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="20828at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003712">
        <property type="term" value="F:transcription coregulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019035">
        <property type="entry name" value="Mediator_Med12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46567:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09497">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01281">
        <property type="entry name" value="Med12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Mediator complex subunit Med12" evidence="7">
        <location>
            <begin position="159"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="782"/>
            <end position="816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1404"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1814"/>
            <end position="1872"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1922"/>
            <end position="1962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="801"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1819"/>
            <end position="1831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="1842"/>
            <end position="1851"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1852"/>
            <end position="1861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1933"/>
            <end position="1942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2253" mass="246444" checksum="4C0F9C148FA823ED" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGI0</accession>
    <name>A0A8T0IGI0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G025600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + acetyl-CoA = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 2 lipoyl cofactors covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGI0"/>
    <dbReference type="OrthoDB" id="537444at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06849">
        <property type="entry name" value="lipoyl_domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000010">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.559.10:FF:000003">
        <property type="entry name" value="Acetyltransferase component of pyruvate dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="entry name" value="E3-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151:SF90">
        <property type="entry name" value="DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52777">
        <property type="entry name" value="CoA-dependent acyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="Single hybrid motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="98"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="231"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="368"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="182"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="316"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="215"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="323"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0581986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="668" mass="69728" checksum="E6E4AE9E8E2FB247" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGR8</accession>
    <name>A0A8T0IGR8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G035600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35486">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35486:SF1">
        <property type="entry name" value="OS02G0689500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="476" mass="52046" checksum="913399703A0F2BAE" modified="2022-10-12" version="1">MRECKRHPSESQPGGGVCARCLEERLLWLWKGESFRGDDREEVPSASTSAGASVPEQRLGHSGSSHNPDARPEPAASSIASVRKQLQVHGVARPGGARARAGVSSDVVNGDNHRDGVGLGAVVVASSGDGAERTCVGDGDPGFGNLTLHDSKGVMEEWTEFHARRRRNLEPGLEGELDSCKAKSKSFDLIETIEAGASDDATMDTENLQSVARNPELVILMNAQKMRSQSMPLDNRSAEDTALRVINEQADDLFFDEFDAYGIAEDVQDRDGGGEALQESMAAQRCFSPVWQSRKSPKWVKVLVSPMTSRNRVFPSRSKEDARKGRGSRKRGARFASSDWSGSEAHRGGSSPQWMGSSRAEEEMPAHPRTSMRSSVFSWLKQDADTTHHKRYDQGEQLTSSSSSSLTNSVSTDSWLRDLTTVGHLHEIAEEMEIVEESSEEENDLGDMTSFGKFLLLAAQRQPEARLTRLVSANSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHQ1</accession>
    <name>A0A8T0IHQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="5">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G060000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RBR family. Ariadne subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="5"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHQ1"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20346">
        <property type="entry name" value="BRcat_RBR_ANKIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22583">
        <property type="entry name" value="Rcat_RBR_ARI7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23141">
        <property type="entry name" value="RING-HC_ARI6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1750:FF:000005">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000019">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045840">
        <property type="entry name" value="Ariadne"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19422">
        <property type="entry name" value="Ariadne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26000">
        <property type="entry name" value="UBA_ARIH2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="11" id="KW-0862">Zinc</keyword>
    <keyword evidence="9 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="15">
        <location>
            <begin position="139"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="143"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="526"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="530"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0582441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="599" mass="68039" checksum="72A881F586E88F60" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJ86</accession>
    <name>A0A8T0IJ86_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G096100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the gamma-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJ86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd04645">
        <property type="entry name" value="LbH_gamma_CA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047324">
        <property type="entry name" value="LbH_gamma_CA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050484">
        <property type="entry name" value="Transf_Hexapept/Carb_Anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061">
        <property type="entry name" value="DYNACTIN SUBUNIT P25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13061:SF50">
        <property type="entry name" value="GAMMA CARBONIC ANHYDRASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00034694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="28856" checksum="46CDFDBDD623284C" modified="2022-10-12" version="1">MGTLGRVVYSLGKAARTTGQALDRIGSRMQLGYTFKDEVSKHQTILSIFGKSPVIGESTFVAPGASVVGEVHIGEKSSIWYGCVLRGDVHSIKVGSETNIQDNTLVHVAKTNVSGNVQPTIIGNRVTIGHNSVLHACTVEDEAFVGMGSTILDGAVVEKGAMVAAGSVVTQKTRIPTGQIWAGSPAKFLRELTAEEQASLTGNTSIYMDLAEVHAHENSKTFGEIEADKALRRKWDVQDDDYDSHLGIIRSKRPEIEFPNKMISKGPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2024-01-24" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJA9</accession>
    <name>A0A8T0IJA9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C-terminal of Roc (COR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G100200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF1">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1294" mass="147661" checksum="2BC027734F7E353B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJZ4</accession>
    <name>A0A8T0IJZ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G084000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJZ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11459" checksum="081E9633A8C5212A" modified="2022-10-12" version="1">MSHSNMTPKKPVVASKEYPARFLDFLAPRFCKLHADILTSADNPPARPINSAAIRPPTIAVKFGTMHAILLSIISKILLFVSSRASTHKQASMIFFWFSSDNGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMM0</accession>
    <name>A0A8T0IMM0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Peptidase A1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G183500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMM0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05476">
        <property type="entry name" value="pepsin_A_like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034161">
        <property type="entry name" value="Pepsin-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032799">
        <property type="entry name" value="TAXi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032861">
        <property type="entry name" value="TAXi_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683">
        <property type="entry name" value="ASPARTYL PROTEASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13683:SF375">
        <property type="entry name" value="PEPTIDASE A1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14541">
        <property type="entry name" value="TAXi_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14543">
        <property type="entry name" value="TAXi_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="12" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035844126" description="Peptidase A1 domain-containing protein" evidence="13">
        <location>
            <begin position="29"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="14">
        <location>
            <begin position="90"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="12">
        <location>
            <begin position="362"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0584081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="512" mass="55145" checksum="D01E36827798E8C4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INM3</accession>
    <name>A0A8T0INM3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Coiled-coil-helix-coiled-coil-helix domain containing 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G181000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INM3"/>
    <dbReference type="OrthoDB" id="70030at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47587">
        <property type="entry name" value="OS05G0103500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47587:SF2">
        <property type="entry name" value="OS05G0103500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="186" mass="21000" checksum="63A43CB0CF17CB7A" modified="2022-10-12" version="1">MAPAQDAFSLQVTSELMQKLTKENIVAKEPAKGRKPTQKAAAPKPSMKPVEPAPMNLKQDLSLPYYPGFLSSLPGMNKPEVQTHEQTHDLVPIYKVLEETEKLGEKLQKQEEKELEKVKQLAQDLQDKQFRAPSYPIPCQTEKETCLQCYRGSTKSPLECAEAVRVFKECSQRVQQDFAQRTAAPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INM9</accession>
    <name>A0A8T0INM9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G209200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035727382" evidence="2">
        <location>
            <begin position="18"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="23858" checksum="94985A37D5EFB79F" modified="2022-10-12" version="1">MFESRVLVVGVNPLVVASLLGVATDVATDVAGTAAVEVELIRGCDSVLQNLLTGFEDCSLNLGTVVTIRLLDSTNMAEGEIPDVIARGGAAMHAAPDGAPSHPNNAGGAPVLADPNGPAAPHPKRAGGGAAMIPGRRRAGPPPNIRGGAAMHIAGAGAPPHQAHRNAGGVAVALAGPALPPGQQYFDVDGGLEGPRLGRNSLIFFAGPALPPVQQYFDVDSGLEGRRLGRNSLIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP66</accession>
    <name>A0A8T0IP66_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G206900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP66"/>
    <dbReference type="OrthoDB" id="1933362at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053288">
        <property type="entry name" value="TGD_Bridge_Protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34201">
        <property type="entry name" value="GLYCINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34201:SF1">
        <property type="entry name" value="GLYCINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="13567" checksum="3293B4B8279DDA39" modified="2022-10-12" version="1">MADDDRKGIMSRLPKLRTHDWGTLGPAFGYGIGCGVGFGAGIVGGAGLGLGFPGLQVGFGVGAGCGVGIGFGYGLGKGRAYDDNVTYSNIGRLPKRQKSFAGSTGAELGAIVDDFVTGVKRALEGIKTNDGKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPM7</accession>
    <name>A0A8T0IPM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Beta-catenin-like protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G234100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000245">
        <property type="entry name" value="Beta-catenin-like protein 1 isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039678">
        <property type="entry name" value="CTNNBL1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013180">
        <property type="entry name" value="CTNNBL1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978:SF0">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14978">
        <property type="entry name" value="BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08216">
        <property type="entry name" value="CTNNBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01156">
        <property type="entry name" value="DUF1716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Beta-catenin-like protein 1 N-terminal" evidence="6">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0584786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="529" mass="59640" checksum="F8171CA4651F48A6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISV8</accession>
    <name>A0A8T0ISV8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G044000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="14"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="14712" checksum="475CE59F89E6C069" modified="2022-10-12" version="1">MQQTECSVRAPASKPQTSNLSSPSANPEKHTQCMSGDEEQPSGQAISPKGLTPDVTLALPCSHQSSYHKPSGSLLRLCHVAGTPECNDLFGSLLGRTSYYFSGVGFGISIAGWSNQLLGGLVELLRPIGIRGLDGLVGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IT66</accession>
    <name>A0A8T0IT66_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G126900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IT66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0052">Apoplast</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035965170" description="Germin-like protein" evidence="10">
        <location>
            <begin position="30"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="11">
        <location>
            <begin position="69"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0586914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="24442" checksum="11AA32F897314A72" modified="2022-10-12" version="1">MAQSSSTTVLSLLFIALCAAASFMSAVHAADPDPLQDYCVADVSANAPLLNGYACKPRSEATDEDFTFTGFRKAPKSDSEIAKSPTGAIAVLTTPLTYPGINTQGITHARLDFAVGGVTPLHTHPRAAETIFILKGTVYTGFISDDNKLFASTLKQGDVFVFPKGLSHFQINVGKETAISFNTLTSQSPGFLVTANQIFQTNITSAVIEKSFGIDADLVKKLTATVPNFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITD7</accession>
    <name>A0A8T0ITD7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PARP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G087500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITD7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="185" mass="20954" checksum="68DC1BCAE982AFDE" modified="2022-10-12" version="1">MNEILPFSIIFEAFKSFLRRSCFGHKWERVSQLLLEVCGTAMSEYWTISQGRANHTGHTCRECRGTIFTNEPIYVRDGRKIRLFYHRKCYSGDADPRTQASSSFTDKSLRIRESAPEHKGRGKWWTSEFGYRGHVVAPPTIRNLASPLPSQALRRTTSVIQSGSSSSRVGANMASNNSFKTVLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW47</accession>
    <name>A0A8T0IW47_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G160800</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015421">
        <property type="term" value="F:ABC-type oligopeptide transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010329">
        <property type="term" value="F:auxin efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043481">
        <property type="term" value="P:anthocyanin accumulation in tissues in response to UV light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009926">
        <property type="term" value="P:auxin polar transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090374">
        <property type="term" value="P:oligopeptide export from mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009640">
        <property type="term" value="P:photomorphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009958">
        <property type="term" value="P:positive gravitropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1900459">
        <property type="term" value="P:positive regulation of brassinosteroid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008361">
        <property type="term" value="P:regulation of cell size"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009637">
        <property type="term" value="P:response to blue light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009741">
        <property type="term" value="P:response to brassinosteroid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048367">
        <property type="term" value="P:shoot system development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18577">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18578">
        <property type="entry name" value="ABC_6TM_Pgp_ABCB1_D2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03249">
        <property type="entry name" value="ABC_MTABC3_MDL1_MDL2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000009">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1560.10:FF:000029">
        <property type="entry name" value="ABC transporter B family member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000251">
        <property type="entry name" value="ABC transporter B family member 19"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394:SF11">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43394">
        <property type="entry name" value="ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="ABC transporter transmembrane region"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="364"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="732"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="778"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="858"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="883"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="960"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="96"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="421"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="13">
        <location>
            <begin position="736"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="1058"/>
            <end position="1294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0587385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1304" mass="141327" checksum="9264972746CDB7FD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX37</accession>
    <name>A0A8T0IX37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="5">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G158600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:16185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17478"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.2.1.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="5"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07130">
        <property type="entry name" value="ALDH_F7_AASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000018">
        <property type="entry name" value="Alpha-aminoadipic semialdehyde dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521:SF1">
        <property type="entry name" value="ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="35"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0587356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="559" mass="60668" checksum="6A083F1B61600DDB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J025</accession>
    <name>A0A8T0J025_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chalcone-flavonone isomerase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G228800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the chalcone isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J025"/>
    <dbReference type="OrthoDB" id="18193at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.890.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016087">
        <property type="entry name" value="Chalcone_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016088">
        <property type="entry name" value="Chalcone_isomerase_3-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016089">
        <property type="entry name" value="Chalcone_isomerase_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036298">
        <property type="entry name" value="Chalcone_isomerase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47698:SF2">
        <property type="entry name" value="FATTY-ACID-BINDING PROTEIN 3, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02431">
        <property type="entry name" value="Chalcone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54626">
        <property type="entry name" value="Chalcone isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chalcone isomerase" evidence="3">
        <location>
            <begin position="13"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="22457" checksum="E0C97C4DB1A84575" modified="2022-10-12" version="1">MSETMPESFVESVTGVKFPASLTSPGSSTQLAFAGAGVREKKVAFINVKVYAVALYVESGVKAVLAAWRGQSVSSLSNNSAFFNSALSAPVQKALQIVLVRDITGAQFWGALSESLQPRLKAAKAGEAGDKALSELGKVFQTRPLTNGMSITLNWIHPSTLQVAVAPSPSGKATVEASIDNKALVSSIFDIYVGDQPISPGAKFQFASGLARFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0W2</accession>
    <name>A0A8T0J0W2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G272700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0W2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="47" mass="5325" checksum="EFC8EE0289784E10" modified="2022-10-12" version="1">MCLQKDSSKSMIHQQIEAINRSKLTSCNKLLDLVSLDLVFDSSTRRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2N0</accession>
    <name>A0A8T0J2N0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PLAC8 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G293300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2N0"/>
    <dbReference type="OrthoDB" id="6407410at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009975">
        <property type="term" value="F:cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051762">
        <property type="term" value="P:sesquiterpene biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021369">
        <property type="entry name" value="DUF2985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045:SF30">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31045">
        <property type="entry name" value="PLAC8 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11204">
        <property type="entry name" value="DUF2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="398"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="580" mass="63713" checksum="517FA42ACA1253E7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2R0</accession>
    <name>A0A8T0J2R0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="4">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G015600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a 5'-end NAD(+)-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:60876"/>
            <dbReference type="Rhea" id="RHEA-COMP:15698"/>
            <dbReference type="Rhea" id="RHEA-COMP:15719"/>
            <dbReference type="ChEBI" id="CHEBI:14649"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:144029"/>
            <dbReference type="ChEBI" id="CHEBI:144051"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:60877"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nudix hydrolase family. NudC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2R0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.79.10:FF:000040">
        <property type="entry name" value="Nudix hydrolase 19, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001299">
        <property type="entry name" value="PRK00241.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF6">
        <property type="entry name" value="NAD-CAPPED RNA HYDROLASE NUDT12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="12">
        <location>
            <begin position="194"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="329"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="335"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0589356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="387" mass="43247" checksum="5BF43F899B19EF50" modified="2022-10-12" version="1">MMSGRETVNAFAGNPIVGGKREAEEVEEVLRSPEAASKVKVLPMCDGKPLVEAQSQGLVPWRLAWQELDDIQYYGSAEERNIQLVYVGDGDGFSYFAIAVPAKDFGDRQELKSLADGFGKEGLTFYDLRSLMQAADFGNHDIMGELSIAGHARAMMEWHKQAKYCGRCGTSTRPILCGQRRQCTNAKCNNKLYPRIDPVVIMLVIDKERDCAILGRQSRFIPRMWSCIAGFIEPGESLEEAVRRETREEVGLEVGEIVYHSSQPWPVGPSSMSCQLMVGFFAYAKSFDIRVDKKELEDAQWHRREDIRRILQNTRYKSDQQEAIQKIQKAASGNGEAQVQGRTSSDSKKESTTGTSTLGFVPGPYAIAHHLISTWANEGPVMTQSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4W6</accession>
    <name>A0A8T0J4W6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G138800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4W6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="235" mass="26373" checksum="04B34EC51CC2CF23" modified="2022-10-12" version="1">MAPSANGQKAGGAQQHRVYVVERRAEFRELNAQIDPSADQQPFEPEISYLDFAYLDEKQAYAIAIREQILELDENGKAHDGRKVAAQANLSLKERLKGIHKVVDAAADGEGGPGEAPVVKFEVLEFPLAPVQAFQEGDLLKELGDQSDSEDIEEEEEEEEEEEELGDEEDVDEEDVEEEVYEGEEGVEEEEVEEEEDEEAEDDLEDLDDEDEGEEVDDDEDDDSDAAPQTKKQRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5R2</accession>
    <name>A0A8T0J5R2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Ferritin</fullName>
            <ecNumber evidence="14">1.16.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_1G161000</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>4 Fe(2+) + O2 + 4 H(+) = 4 Fe(3+) + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:11148"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.16.3.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the ferritin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.1" evidence="14"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5R2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004322">
        <property type="term" value="F:ferroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01056">
        <property type="entry name" value="Euk_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1260.10:FF:000006">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014034">
        <property type="entry name" value="Ferritin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431:SF123">
        <property type="entry name" value="FERRITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00540">
        <property type="entry name" value="FERRITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00204">
        <property type="entry name" value="FERRITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="3 14" id="KW-0409">Iron storage</keyword>
    <keyword evidence="6 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="15" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035712665" description="Ferritin" evidence="15">
        <location>
            <begin position="18"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Ferritin-like diiron" evidence="16">
        <location>
            <begin position="102"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR601519-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0591244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="269" mass="29616" checksum="40C5EE483919373C" modified="2022-10-12" version="1">MLTFGLSSLVMAQAATATAPGAVCAFSTSTAGNVSFKASSVNVVSWRSQPKRSLTVQASGGSENTNVGFAKAETGIVFEPFAEVQSELVKVSSAYPASLARQRFAPSCEAAINDQINVEYNVSYVYHALYAYFDRDNVGLPGFAKFFKESSEEEREHAEKLMKYQNKRGGRVKLNTIQSPVMEFDHTEKGDALYSMELALALEKLVNEKLLSLHQVAVDNNDPEMCDFIEGEYLNEQVEAIKKISGYVSQLRRVGKGHGVYHFDLQLQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6N5</accession>
    <name>A0A8T0J6N5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G110300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8544" checksum="8575C04C27F91050" modified="2022-10-12" version="1">MADEMVCTVLQARFNACWNILTRGHAGHGGVGRWRSEKTAVVAASDREHGPDAAVRKRWILNPWTVQSLRTRLAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6T6</accession>
    <name>A0A8T0J6T6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G104700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6T6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17371" checksum="761169BDE91DE69D" modified="2022-10-12" version="1" fragment="single">MWSAERREEACAQPPSQHLRCDPEIRETQVRETLREQDLDEQWRCCAEEPGCGEELEVPERFSVAFIHDTKVLNAPFKLAVAVGQCAVKASNSSVSCVCLRSNSVVVAMIPVQRWSMLATVGSCTESLLPDPAQLGKLENVCFAPIPRLPPIYLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J980</accession>
    <name>A0A8T0J980_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein SDA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G253500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Required for 60S pre-ribosomal subunits export to the cytoplasm.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDA1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J980"/>
    <dbReference type="OrthoDB" id="2196187at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027312">
        <property type="entry name" value="Sda1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012977">
        <property type="entry name" value="SDA1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730">
        <property type="entry name" value="HSDA/SDA1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12730:SF0">
        <property type="entry name" value="PROTEIN SDA1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08158">
        <property type="entry name" value="SDA1_HEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SDA1 N-terminal" evidence="3">
        <location>
            <begin position="81"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="249"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="512"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="717"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="249"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="519"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="717"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU365057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="815" mass="91139" checksum="E1D855CEBDB692AE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9G3</accession>
    <name>A0A8T0J9G3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_1G210200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9G3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000177">
        <property type="entry name" value="Cysteine-rich receptor-like protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035917432" description="Protein kinase domain-containing protein" evidence="15">
        <location>
            <begin position="28"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="505"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="533"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0591896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="838" mass="93154" checksum="0F864844138E8827" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA90</accession>
    <name>A0A8T0JA90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G283100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA90"/>
    <dbReference type="OrthoDB" id="1933492at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039391">
        <property type="entry name" value="Phytocyanin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003245">
        <property type="entry name" value="Phytocyanin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021">
        <property type="entry name" value="BLUE COPPER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021:SF496">
        <property type="entry name" value="OS08G0482700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02298">
        <property type="entry name" value="Cu_bind_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51485">
        <property type="entry name" value="PHYTOCYANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035871650" description="Phytocyanin domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Phytocyanin" evidence="2">
        <location>
            <begin position="26"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="179" mass="19125" checksum="0780910281D330EF" modified="2022-10-12" version="1">MKHFKSAGCTLAVLVVVMLAREAAGVTIVLGGLDGWTNSANVDYNQWLSTYKMKIGDTLQFDNNDSTDHTAVVVDKEAYDTCGKSGQMDGPFTISPGIGYKLTWFQSGDAYVICDIPGHCIQGQKVYIQVLNSDGTVNTTANQAPGKSAAPQMPGFSWTSQLITIVVSTFSLMVAATTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAV4</accession>
    <name>A0A8T0JAV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rubisco LSMT substrate-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G287200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAV4"/>
    <dbReference type="OrthoDB" id="341421at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1410.10:FF:000003">
        <property type="entry name" value="Rubisco methyltransferase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1420.10">
        <property type="entry name" value="Rubisco LSMT, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015353">
        <property type="entry name" value="Rubisco_LSMT_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036464">
        <property type="entry name" value="Rubisco_LSMT_subst-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF9">
        <property type="entry name" value="RUBISCO METHYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09273">
        <property type="entry name" value="Rubis-subs-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81822">
        <property type="entry name" value="RuBisCo LSMT C-terminal, substrate-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rubisco LSMT substrate-binding" evidence="5">
        <location>
            <begin position="376"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF09273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0592877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="525" mass="58638" checksum="70643858EF860899" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB72</accession>
    <name>A0A8T0JB72_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G260800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB72"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.80:FF:000003">
        <property type="entry name" value="WRKY transcription factor 57"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044810">
        <property type="entry name" value="WRKY_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221:SF334">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR 57-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="7">
        <location>
            <begin position="339"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="147"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="578"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="41"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="157"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="209"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="253"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="317"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="580"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="613"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="637"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="660"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="695"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0592536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="728" mass="77477" checksum="A0F3FD6FB423391B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6I5</accession>
    <name>A0A8T0G6I5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G126900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6I5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="12130" checksum="8FD3BE48A417AF91" modified="2022-10-12" version="1">MPFIIANYYYNYQSEDVLFFRNTTYKHLANIEVANDNSEVVGTSKIPWGGNLLQEELIVGRLQHMCLMCDDDAAEDGEDGLISVYDDTATLEVKVKGNHLTCGYWTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G723</accession>
    <name>A0A8T0G723_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">protein-ribulosamine 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.172</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G142500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>N(6)-D-ribulosyl-L-lysyl-[protein] + ATP = N(6)-(3-O-phospho-D-ribulosyl)-L-lysyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:48432"/>
            <dbReference type="Rhea" id="RHEA-COMP:12103"/>
            <dbReference type="Rhea" id="RHEA-COMP:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:90418"/>
            <dbReference type="ChEBI" id="CHEBI:90420"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.172"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:48433"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.172" evidence="1"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G723"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102193">
        <property type="term" value="F:protein-ribulosamine 3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="FRUCTOSAMINE 3 KINASE-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149:SF11">
        <property type="entry name" value="PROTEIN-RIBULOSAMINE 3-KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00048655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="389" mass="43871" checksum="F5DBD6DFCB00FED4" modified="2022-10-12" version="1">MASAMLLCSHTPWPWQPPSAAMKNYHSRSGSDGGEQLEIASGARFPWPPPGQTLPAKTKHMRWECRASWFDFSSESSTKSGGRMTTGDFTILSHLKELGCGELLRRPREVHFSGCINESYAFHCAGGDFFVKINRASEMDSMFVGESEALKRIEATETVTVPTPLGCGNLPDGGSYIIMKHLRFRPFGMMQVSSQSALGRDLARLHLAEAGNLFGFPMQTRVGIVPLDNRWSSSWCEFFIEQRLRDRFQRVCERLEEDKTDIEEKGAMVLKIANTILKDHNPKPCILHGDLWMGNSGLVATGEVAIFDPACFIGDAEFDLAFEGWKPVPDFPGLSVDFYTAYHQLLPQAPGFEKRHQLYQLFHLLNHFVIYGGEYYTHVMDMMDRILDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCD2</accession>
    <name>A0A8T0GCD2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G031600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCD2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="14063" checksum="812F2EA75D9052ED" modified="2022-10-12" version="1">MWPQKYSHKDLHFNLRVVLYQQQNQYHLSLDCSTSSQHTPSKLHFLPRMKIIMCHRYPLDHGNLHSGHRLLVPENQMSSVRAPCPAENSCQHLLQLHLNPDTVGITLRLRNAAHEGSRTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD20</accession>
    <name>A0A8T0GD20_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G067800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. ABCF family. EF3 (TC 3.A.1.121) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD20"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000309">
        <property type="entry name" value="ABC transporter ATP-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000011">
        <property type="entry name" value="Putative ABC transporter ATP-binding component"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051309">
        <property type="entry name" value="ABCF_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855">
        <property type="entry name" value="ABC TRANSPORTER ATP-BINDING SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42855:SF1">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="138"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="466"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="103"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="683"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="721"/>
            <end position="733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00061344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="733" mass="81952" checksum="26957CC85ECBC9D9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GES1</accession>
    <name>A0A8T0GES1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_11G095900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25017"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
            <dbReference type="ChEBI" id="CHEBI:58456"/>
            <dbReference type="EC" id="3.1.3.67"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PTEN phosphatase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GES1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016314">
        <property type="term" value="F:phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14509">
        <property type="entry name" value="PTP_PTEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000053">
        <property type="entry name" value="Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051281">
        <property type="entry name" value="Dual-spec_lipid-protein_phosph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055183">
        <property type="entry name" value="PTEN2A/B_C2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045101">
        <property type="entry name" value="PTP_PTEN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014020">
        <property type="entry name" value="Tensin_C2-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029023">
        <property type="entry name" value="Tensin_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305">
        <property type="entry name" value="PHOSPHATASE WITH HOMOLOGY TO TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12305:SF96">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND PROTEIN-TYROSINE-PHOSPHATASE PTEN2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22918">
        <property type="entry name" value="PTEN2_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22785">
        <property type="entry name" value="Tc-R-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01326">
        <property type="entry name" value="PTEN_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51182">
        <property type="entry name" value="C2_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51181">
        <property type="entry name" value="PPASE_TENSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphatase tensin-type" evidence="8">
        <location>
            <begin position="187"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="7">
        <location>
            <begin position="294"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="C2 tensin-type" evidence="9">
        <location>
            <begin position="373"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="508"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="7"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="514"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0557017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="684" mass="72876" checksum="C1AB91E19BAA0CC3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF88</accession>
    <name>A0A8T0GF88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cyclin-dependent kinase E-1</fullName>
            <ecNumber evidence="3">2.7.11.22</ecNumber>
            <ecNumber evidence="2">2.7.11.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_11G092100</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10216"/>
            <dbReference type="Rhea" id="RHEA-COMP:11321"/>
            <dbReference type="Rhea" id="RHEA-COMP:11322"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43176"/>
            <dbReference type="ChEBI" id="CHEBI:68546"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.22" evidence="3"/>
    <dbReference type="EC" id="2.7.11.23" evidence="2"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF88"/>
    <dbReference type="OrthoDB" id="6284126at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07842">
        <property type="entry name" value="STKc_CDK8_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000350">
        <property type="entry name" value="Cyclin-dependent kinase e-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000374">
        <property type="entry name" value="Putative cyclin-dependent kinase E-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF495">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 14 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="19"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="355"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="16">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="16">
        <location>
            <begin position="434"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00067338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0556974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="475" mass="53983" checksum="AF1DF00F57E66C55" modified="2022-10-12" version="1">MVADGAGKQRTRPEWLQQYELVGKIGEGTYGLVYLAKSKEPAHRGTKIAIKKFKQSKEGDGVSPTAIREIMLLRECIHENIVKLVNVHINHGDMSLYLAFDYAEHDLYEIIRHHREKISCNINAYTVKSLLWQILNGLNYLHNNWIIHRDLKPSNILVMGEGEEQGVVKIGDFGLARIFQAPLRPLSENGVVVTIWYRAPELLLGSKHYTSAVDMWAVGCIFAELLTLKPLFQGIEDKSSPNPFQLDQLDKIFKVLGNPNADKWPTLTTLPHWQSNRQQIQSRKYENPGLYSIVQLPPKSPGFDLLSRMLEYDPVKRITAAQALDHEYFRNDPIPGRNSLVPANAADKVIPYPQRPVDYSTDFDGTTAPPPPQMPNSSNMSNQLHQSMNVGMQQQQQHRVQNPNNLGVNQPVAMHGMNSGSSMYVQRGNAAALQQQQQQQQQQQQQQQQQGMRRKEQTNMGYPGHYQPPNKSRRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG06</accession>
    <name>A0A8T0GG06_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G133700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG06"/>
    <dbReference type="OrthoDB" id="24670at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000234">
        <property type="entry name" value="WD repeat-containing protein LWD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045159">
        <property type="entry name" value="DCAF7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19919">
        <property type="entry name" value="WD REPEAT CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0007">Acetylation</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="4">
        <location>
            <begin position="254"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="335" mass="37704" checksum="B813C882CD89DB2B" modified="2022-10-12" version="1">MNLNIQDARRRGVYTYDAPWTIYGMNWSVRKDRKFRLAVGSFIEAYKNKVEIIQLDDDSGKFHANPRLAFDHPYPATKIMFIPDMEGEKLDLMATTGDNLRIWQIHNDRVQLRSLLNNKRNSDYCSPLTSFDWNDSDLRRLGTCSIDTTCTIWDIETGVADTQLIAHDKEVHDIAWGGVGVFASVSADGSVRVFDLRDKQHSTIIYESPQPDSVPLLRLGWNKQDPRYLATILMDSSKVVILDIRFPSVPVSELQRHQACVNAIAWAPHSASHICTAGDDSQALIWDMSAKAVEGGLDPMLAYTAGGEVNQLQWSASHSDWVAIAFASHLQVLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG40</accession>
    <name>A0A8T0GG40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">sucrose-phosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_11G170600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>sucrose 6(F)-phosphate + H2O = sucrose + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57723"/>
            <dbReference type="EC" id="3.1.3.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; sucrose biosynthesis; sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sucrose phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.24" evidence="5"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050307">
        <property type="term" value="F:sucrose-phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02605">
        <property type="entry name" value="HAD_SPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006380">
        <property type="entry name" value="SPP-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013679">
        <property type="entry name" value="SPP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051518">
        <property type="entry name" value="Sucrose_Phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012847">
        <property type="entry name" value="Sucrose_phosphatase_pln/cyn"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01482">
        <property type="entry name" value="SPP-subfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01485">
        <property type="entry name" value="SPP_plant-cyano"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46521">
        <property type="entry name" value="SUCROSE-PHOSPHATASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46521:SF4">
        <property type="entry name" value="SUCROSE-PHOSPHATASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05116">
        <property type="entry name" value="S6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08472">
        <property type="entry name" value="S6PP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01141">
        <property type="entry name" value="C2.B.1:_Sucrose_Phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01140">
        <property type="entry name" value="C2.B:_Phosphomannomutase_and_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00043">
        <property type="entry name" value="sucrose-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sucrose phosphatase-like" evidence="10">
        <location>
            <begin position="8"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="Sucrose-phosphatase C-terminal" evidence="11">
        <location>
            <begin position="287"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="419"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="467"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0557980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="529" mass="58742" checksum="FB33861F790EC866" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHL2</accession>
    <name>A0A8T0GHL2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">L-aspartate oxidase</fullName>
            <ecNumber evidence="4 10">1.4.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_10G066400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the oxidation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-aspartate + O2 = iminosuccinate + H2O2</text>
            <dbReference type="Rhea" id="RHEA:25876"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="1.4.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (oxidase route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.16" evidence="4 10"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008734">
        <property type="term" value="F:L-aspartate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.700.10:FF:000002">
        <property type="entry name" value="L-aspartate oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.100">
        <property type="entry name" value="Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-dep_OxRdtase_2_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005288">
        <property type="entry name" value="NadB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00551">
        <property type="entry name" value="nadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716">
        <property type="entry name" value="L-ASPARTATE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42716:SF2">
        <property type="entry name" value="L-ASPARTATE OXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-dependent oxidoreductase 2 FAD-binding" evidence="12">
        <location>
            <begin position="122"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="Fumarate reductase/succinate dehydrogenase flavoprotein-like C-terminal" evidence="13">
        <location>
            <begin position="564"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="577"/>
            <end position="604"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00050942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0558946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="684" mass="74676" checksum="69AF8DBE65C4C695" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHW9</accession>
    <name>A0A8T0GHW9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mitogen-activated protein kinase kinase kinase</fullName>
            <ecNumber evidence="2">2.7.11.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_11G164100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.25" evidence="2"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHW9"/>
    <dbReference type="OrthoDB" id="266718at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004709">
        <property type="term" value="F:MAP kinase kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06606">
        <property type="entry name" value="STKc_MAPKKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000382">
        <property type="entry name" value="Mitogen-activated protein kinase kinase kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000387">
        <property type="entry name" value="Serine/threonine-protein kinase STE11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF56">
        <property type="entry name" value="MAPKK KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="15"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="458"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="523"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="644"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="523"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="542"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="575"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0557884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="681" mass="74539" checksum="DF555E2D1228CC44" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIT1</accession>
    <name>A0A8T0GIT1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G063200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="7764" checksum="E80E90EF6AE1FF79" modified="2022-10-12" version="1">MVPNVPPQLHTELKSELLVKQTPGFTAKNSREGITNGDCEITEAGISTTRHRSDPHQTDAQQACIHVSIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK10</accession>
    <name>A0A8T0GK10_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Sec-independent protein translocase protein TATB, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_10G136000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK10"/>
    <dbReference type="OrthoDB" id="2017985at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.3310:FF:000003">
        <property type="entry name" value="Sec-independent protein translocase protein TATB, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.3310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATA, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33162:SF3">
        <property type="entry name" value="SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATB, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="9" id="KW-0811">Translocation</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="161"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0559876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="31193" checksum="99307050A659A370" modified="2022-10-12" version="1">MATMAGVVCSRASLLPCAAHFARTTVDIPSCSTSSGSSGSVSGGLHSAVLSRQLGCRKTSLVLRARAFSSASSSFQGRLCLVLSCPTGKVREGKRSGVRASLLGVGAPEALVIGVVALLVFGPKGLAEVARTLGKSLRAFQPTIKELQQVSREFKATLEQEIGLDELRNPTPYDSPPTSTPSRPNTVSSTPTSMPTTLSATEAPPAAPKTEEAPAPPKPYTTEDYVRITEDQAKALVSEEQRKASEAAAWGGAPPVKPVAETSSEDQAQMSADSAAKDGSGVVGSTPTEPLEKSSDNGSPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKB6</accession>
    <name>A0A8T0GKB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phospholipase</fullName>
            <ecNumber evidence="6">3.1.4.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_10G042100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1,2-diacyl-sn-glycero-3-phosphate + choline + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14445"/>
            <dbReference type="ChEBI" id="CHEBI:15354"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="3.1.4.4"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phospholipase D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.4" evidence="6"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004630">
        <property type="term" value="F:phospholipase D activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009395">
        <property type="term" value="P:phospholipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01254">
        <property type="entry name" value="PH_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09138">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09141">
        <property type="entry name" value="PLDc_vPLD1_2_yPLD_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06895">
        <property type="entry name" value="PX_PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.870.10:FF:000011">
        <property type="entry name" value="Phospholipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016555">
        <property type="entry name" value="PLipase_D_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015679">
        <property type="entry name" value="PLipase_D_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896:SF76">
        <property type="entry name" value="PHOSPHOLIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18896">
        <property type="entry name" value="PHOSPHOLIPASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00614">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009376">
        <property type="entry name" value="Phospholipase_D_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="448"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="917"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="622"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="708"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="723"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR009376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0558629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1126" mass="127410" checksum="2335724538BC9B9F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKM4</accession>
    <name>A0A8T0GKM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Lipoxygenase</fullName>
            <ecNumber evidence="11">1.13.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G154800</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.</text>
    </comment>
    <comment type="pathway">
        <text evidence="11">Lipid metabolism; oxylipin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the lipoxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.-" evidence="11"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034440">
        <property type="term" value="P:lipid oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031408">
        <property type="term" value="P:oxylipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.375.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.372.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.245.10">
        <property type="entry name" value="Lipoxygenase-1, Domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.60.20">
        <property type="entry name" value="PLAT/LH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000907">
        <property type="entry name" value="LipOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013819">
        <property type="entry name" value="LipOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036226">
        <property type="entry name" value="LipOase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020834">
        <property type="entry name" value="LipOase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001246">
        <property type="entry name" value="LipOase_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027433">
        <property type="entry name" value="Lipoxygenase_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001024">
        <property type="entry name" value="PLAT/LH2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036392">
        <property type="entry name" value="PLAT/LH2_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11771">
        <property type="entry name" value="LIPOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00305">
        <property type="entry name" value="Lipoxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01477">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00087">
        <property type="entry name" value="LIPOXYGENASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00468">
        <property type="entry name" value="PLTLPOXGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00308">
        <property type="entry name" value="LH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49723">
        <property type="entry name" value="Lipase/lipooxygenase domain (PLAT/LH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48484">
        <property type="entry name" value="Lipoxigenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00081">
        <property type="entry name" value="LIPOXYGENASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51393">
        <property type="entry name" value="LIPOXYGENASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50095">
        <property type="entry name" value="PLAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 11" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 11" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 11" id="KW-0925">Oxylipin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLAT" evidence="13">
        <location>
            <begin position="97"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoxygenase" evidence="14">
        <location>
            <begin position="227"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0560106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="934" mass="104771" checksum="264CF98CC8C9660C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLE8</accession>
    <name>A0A8T0GLE8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G100400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7866" checksum="871140992B266952" modified="2022-10-12" version="1">MSQGLSPRPQWLNLVIAPCRPRDEEEPFWLLGRCRVEIRIQSEVAGWAIWVLEIGELVLCGGFLRCGSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN50</accession>
    <name>A0A8T0GN50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G180900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6440" checksum="1DA067465F74EA63" modified="2022-10-12" version="1">MVANGGLNCRYGVSIRPSFSLCGTDTVVAAVFGIVRLQLAAEQYHMELAYGIGGLFTVVVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN70</accession>
    <name>A0A8T0GN70_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G029400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11555" checksum="5757F00D4627B5D8" modified="2022-10-12" version="1">MISITLHPPPLHPPLHTLPPSTTCRWIHLPSCSPPLPPGLNRLHHWTTDLRNSETAELRSLHELRHLMSTGKNLDIQDDVDDAVAGSRDVKLRQQVGVAAGVGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQG5</accession>
    <name>A0A8T0GQG5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G049500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQG5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="117"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="165" mass="19199" checksum="CBBF5C3239E906E2" modified="2022-10-12" version="1">MDLLFWGRTTLDAQLKVWQRSMCSELPRGTKKLECENTSRLDQLCSIASVTQPTYIAESPWFVRRKSVWQPTSQRGSKYDHLHAPPVKQPTREMRIDEELGLNWEQEGWKSGGKSLHNRELPVLEKGNDGPKQLQRSHPAPYPANYFSWRPRPEVQVAIYEVCHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQM9</accession>
    <name>A0A8T0GQM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytochrome b561 and DOMON domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G022100</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 2 heme b groups non-covalently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045265">
        <property type="entry name" value="AIR12_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017214">
        <property type="entry name" value="UCP037471"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF199">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03188">
        <property type="entry name" value="Cytochrom_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04526">
        <property type="entry name" value="DUF568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037471">
        <property type="entry name" value="UCP037471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50836">
        <property type="entry name" value="DOMON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0732">Signal</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035748613" description="Cytochrome b561 and DOMON domain-containing protein" evidence="11">
        <location>
            <begin position="26"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="DOMON" evidence="12">
        <location>
            <begin position="48"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="13">
        <location>
            <begin position="177"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037471-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0560887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="404" mass="43292" checksum="44360BA16099676D" modified="2022-10-12" version="1">MGSRGGRDVLLLCVVMGALFGVAFSAQSCSTLLASNKGFSACQDLPKLASTLAWRIDNATNSVDFAFSASAPNANGWVAWGINPTAANGQWMAGTQALVAYQTAAGAKVAGYPITGAMKGGAPAVPGTLSVNFTGTSTVITGTEMTIYTTLALKANDSFTMNNVWNVGPSVDQTSFAIASHSLSGDSLSSGSVIDLSSGQAFNNIELPNQKLKNNHAIISAVAWGLLLPLGVMAARYLRPFSNGNPAWFYIHVTCQCTGYALGVIAWALGMRLHSLNQGLVPYKHRNLGISIFALATLQVLAIFLRPNPDAKYRKYWNVYHHSVGYATLVLIIINIFEGLDLLQPGNKWTLIYVIILCALGAISLIMEIITWSKWIRERNSNKQAMHGSQYKGSSAYRSGREDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSC1</accession>
    <name>A0A8T0GSC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G156500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NRAMP (TC 2.A.55) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015086">
        <property type="term" value="F:cadmium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034755">
        <property type="term" value="P:iron ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00221">
        <property type="entry name" value="NRAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01197">
        <property type="entry name" value="nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF037982">
        <property type="entry name" value="Nramp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706:SF33">
        <property type="entry name" value="NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="157"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0562571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="564" mass="62687" checksum="061A0CFECF47203A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVT4</accession>
    <name>A0A8T0GVT4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ubiquitin thioesterase OTU</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G146300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVT4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22760">
        <property type="entry name" value="OTU_plant_OTU4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.80:FF:000007">
        <property type="entry name" value="OTU domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047947">
        <property type="entry name" value="OTU4_OTU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003323">
        <property type="entry name" value="OTU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312">
        <property type="entry name" value="HIV-INDUCED PROTEIN-7-LIKE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13312:SF6">
        <property type="entry name" value="UBIQUITIN THIOESTERASE OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02338">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50802">
        <property type="entry name" value="OTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="OTU" evidence="4">
        <location>
            <begin position="216"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU367104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0562439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="360" mass="39391" checksum="89085657FFFABAFE" modified="2022-10-12" version="1">MVLSMMLKSFSVSASVPGKAYNTVQNYSSFSLRNGGRLKVSSISLTCPQHHPTLCLLAAKIAPTGTSGRTFQQSREISAAFRPSKQLAAAPFSVNRVDVNKNSRVPWAKSSEAFKFSSTNLKATHGKANMSVSSPAPGSPQKLQAVQHRHAPWLLFGLCICLSVAAGSFAPRLLIGSPPAFAEVVVRTAGRPTASGSRCRSSETEESQGKKVHFDYHVTGIPGDGRCLFRAVAHGACLRSGKPAPNEGTQRQMADDLRNKALDELVRRRETSEWFIEGDFDAYVRRMRNPYTWGGEPELLMLSNVLQMPITVYMKHKGGIIAIAEYGQEYGNENPIRVLYHGSGHYEAVQLPGDKRKSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW72</accession>
    <name>A0A8T0GW72_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G018500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW72"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5789" checksum="DBACD987FB86D259" modified="2022-10-12" version="1">MAMMAQLPTTTMPDHLAYCTSSSPKPSLLCLCFQFQSEGGRLNLLLLLLLQCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY95</accession>
    <name>A0A8T0GY95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G167200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12996" checksum="B7D501BAE301D5C7" modified="2022-10-12" version="1">MSESTNRSSVVLANSLKVTFENHCEFSDVLEMACFYWLRFVVCRAHVAPVDLRRNLRSCEILRCNRQIWNDLNILVFLVYVYHARIHPVSPPHSLLLLMDTLKNPRRPSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYQ2</accession>
    <name>A0A8T0GYQ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Uridine kinase</fullName>
            <ecNumber evidence="10">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G024300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>cytidine + ATP = CMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>uridine + ATP = UMP + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the UPRTase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="10"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYQ2"/>
    <dbReference type="OrthoDB" id="106623at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000904">
        <property type="term" value="P:regulation of starch metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000015">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000339">
        <property type="entry name" value="Uridine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001097">
        <property type="entry name" value="PRK00129.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004018">
        <property type="entry name" value="PRK05480.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14681">
        <property type="entry name" value="UPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00988">
        <property type="entry name" value="URIDINKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="11">
        <location>
            <begin position="41"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphoribosyltransferase" evidence="12">
        <location>
            <begin position="257"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0563359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="55129" checksum="1ED19A2FE73B0C39" modified="2022-10-12" version="1">MVKSDPEAIMEATSTAHFSGLHFDDEYPATKYKGANKVPFVIGVAGGTASGKTTVCDMIIQQLHDHRVVLVNQDSFYRGLTPEEMANVGEYNFDHPDAFDTEQLLECLGNLKANQPVQIPVYDFKKHQRCTERFRKVNASDVIIMEGILVFNDPRVRELMNMKIFVDTDADVRLARRIRRDTLERGRDVNGVIEQYGKFVKPAFDDFILPTKKYADVILPRGGDNHVAIDLIVQHIRMKLGQHDLRKIYPNVFVIQSTFQIRGMHTLIRDQETTKHDFVFYADRLIRLIVEHGLGHLPFTEKQVITPTGSIYVGVDFCKQLCGVSIIRSGESMENALRACCKGIKIGKILIHREGDDGKQLIYEKLPHDIADRHVLLMDPILGTGNSAVQAIELLLRKGVPEAHIIFLNLISAPEGIHTVCKRFPLLKIVTSEIDAGLNEVYRVVPGMGEFGDRYFGTDDDGPDQMHPAPIEPKLLQSHLNMPLKSLGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZA5</accession>
    <name>A0A8T0GZA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit L</fullName>
            <shortName evidence="4">eIF3l</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G004400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the eIF-3 subunit L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZA5"/>
    <dbReference type="OrthoDB" id="15082at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005852">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03011">
        <property type="entry name" value="eIF3l"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019382">
        <property type="entry name" value="eIF3l"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13242:SF0">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10255">
        <property type="entry name" value="Paf67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="5">
        <location>
            <begin position="309"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0563098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="62599" checksum="917EECAD4FADE81B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZK0</accession>
    <name>A0A8T0GZK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G162900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="9"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZK0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18037">
        <property type="entry name" value="DEXSc_Pif1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051055">
        <property type="entry name" value="PIF1_helicase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47642:SF5">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="7 9" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="160"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0565086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="701" mass="78679" checksum="1C9DC9BC4FA4F3BF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0H6</accession>
    <name>A0A8T0H0H6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G068100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0H6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035735510" evidence="1">
        <location>
            <begin position="16"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9555" checksum="930A49FDD41D961B" modified="2022-10-12" version="1">MLLLILACQVDDVLPFKPQSELTSSTHSTYPFSTPTQLTKTIISINTDLTSIHFFSNNPAASRKSCNNLKQPIHRHPTEQIHLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Q7</accession>
    <name>A0A8T0H0Q7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G167600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0Q7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287">
        <property type="entry name" value="OS03G0453550 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33287:SF11">
        <property type="entry name" value="OS03G0778400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="244" mass="27468" checksum="93547048C62B0778" modified="2022-10-12" version="1">MSEVESELLEIVSGGPGGGWSSIALDDAEGYWPPRDSGRLSPRSSLRRAHLEEVAGNVGPVSAYVEVRNEWWVEQDPFLGAALRQWEKKLAYFDNSVYRRQKKTYQIRNQIFNLVGIFFIFQGILLVVVSLLKASNGTAHCGLVWSPLALSLFTAWGTGSGVSSKFIRLRALEISIQDEKQAIKTIKYRIQALQARGRWFRFFNDAKDPKQLTPRTFAKSWSFALLALLAATAIFIVSYFVILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H559</accession>
    <name>A0A8T0H559_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspergillus nuclease S1</fullName>
            <ecNumber evidence="3">3.1.30.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G016800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage to 5'-phosphomononucleotide and 5'-phosphooligonucleotide end-products.</text>
            <dbReference type="EC" id="3.1.30.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nuclease type I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H559"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000014">
        <property type="term" value="F:single-stranded DNA endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.575.10:FF:000002">
        <property type="entry name" value="Endonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="entry name" value="P1 Nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146:SF26">
        <property type="entry name" value="ENDONUCLEASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="Phospholipase C/P1 nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="10" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035883259" description="Aspergillus nuclease S1" evidence="11">
        <location>
            <begin position="24"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0565827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="312" mass="34760" checksum="DC1DDCD53554CF98" modified="2022-10-12" version="1">MAAWGGLGRVVLWLLVGVVLCVGSFPGRAGAWGADGHHATCLLAEPLLEPATWKAVRSLLPEYANGSLASLCTWPDDIKWMWKYHWTAPLHYIDTPDFLCRYNYDRDCYDENGHKGYCASGAINNFTSQLTNYHLRESNPPLVTRALETEYNLTEALLFLSHIVGDIHQPLHVGFTSDAGGNTIMVHWYRRKANLHHVWDTEIIDKAKDLYYNKSLLTMVNAIMENITNDGVSKAQMWSECPNGEIACPDTYATEGISLACQYAYRNATPGSTLADEYFLSRLPIVESRLAQGGVRLAAILNRLFGANSTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5S6</accession>
    <name>A0A8T0H5S6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lon N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G112200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5S6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732:SF5">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035766927" description="Lon N-terminal domain-containing protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Lon N-terminal" evidence="2">
        <location>
            <begin position="111"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="37557" checksum="25441A2D2BB5FB85" modified="2022-10-12" version="1">MAITSLAMAALAPLPTFSSSSSSSCACSSASSAPTCSISPRGSLSVQLPLGSSLRLQRWSGLRLGFGQLGSRRFRTGAAGLSGTSGGSGASGALRVFAEMSTLDEATILELPCLPFSPAEVFIPTSSKTLHLYEARFLSLLEEVMAKGNNLLAHIVIEPVKGGEGGVASFVATYGCLARIESVKQLEIGALVSIRGLGRIKMVNLTQMEPFIKSTVMPVRDEYPEERDSLPVKIESLKKTLAEVQQLQIKIKTAKEVPLLTPLEKALQWADKGESDPVVERFVPSREERLSFAALQPIAGASPGELHKLLQERLKAMTTVDTEVRLNNAMDYAEQSRASVAAKVALQSLQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8N9</accession>
    <name>A0A8T0H8N9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein cereblon</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Protein ohgata</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G160400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Has an essential role in mediating growth by negatively regulating insulin signaling. It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Likely a component of a DCX (DDB1-CUL4-X-box) protein ligase complex. May interact with pic/DDB1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRBN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8N9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031464">
        <property type="term" value="C:Cul4A-RING E3 ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15777">
        <property type="entry name" value="CRBN_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.150.20:FF:000005">
        <property type="entry name" value="Blast:Protein cereblon homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1480:FF:000007">
        <property type="entry name" value="Lon protease homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.130.40:FF:000015">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="entry name" value="LON domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.20">
        <property type="entry name" value="Peptide methionine sulfoxide reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034750">
        <property type="entry name" value="CULT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255">
        <property type="entry name" value="CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14255:SF4">
        <property type="entry name" value="PROTEIN CEREBLON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51788">
        <property type="entry name" value="CULT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="8">
        <location>
            <begin position="146"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="CULT" evidence="9">
        <location>
            <begin position="523"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="308"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="308"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00046796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0567783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="631" mass="69661" checksum="C092897FA7A0EEA7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H998</accession>
    <name>A0A8T0H998_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G134700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H998"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="1">
        <location>
            <begin position="123"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="19699" checksum="DE9CE373FF4D0CCD" modified="2022-10-12" version="1">MAQVVGLSPNRMISVSSQDSEIRNAVYISILTFNNLWEIVDFLCFATELRRWYPEVEILKAERRRPPGQAEAQGNNVGVRLVKLRKAAQKRPEPTEISHHETTQTMVIFPKASLQANREGDESWLTKHADFSMCFVMGESAGSNIVHHLGLQFAKSDLNTLSISKRAHLPGTVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAX7</accession>
    <name>A0A8T0HAX7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G182100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAX7"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00177">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045096">
        <property type="entry name" value="EDR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009769">
        <property type="entry name" value="EDR2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002913">
        <property type="entry name" value="START_lipid-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136">
        <property type="entry name" value="ENHANCED DISEASE RESISTANCE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12136:SF100">
        <property type="entry name" value="PROTEIN ENHANCED DISEASE RESISTANCE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07059">
        <property type="entry name" value="EDR2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01852">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00234">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50848">
        <property type="entry name" value="START"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="3"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="START" evidence="5">
        <location>
            <begin position="206"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="137"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="737" mass="82311" checksum="6802FEBF2B152417" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB03</accession>
    <name>A0A8T0HB03_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G052600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15254" checksum="F7EF791321719A59" modified="2022-10-12" version="1">MDPPAAPSSLHPMVNDLNLKLQSPDNKTVYPNGMNKEDSINNVEVIHVMKPRKGPWRVTVDGARVVNDIQPYALVATGTFRASRRTFGSGAHRFHNFTSDSDSSTSAADRQGRSEWQNNLFLCVCSGVLCSILFLFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB35</accession>
    <name>A0A8T0HB35_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G146900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044559">
        <property type="entry name" value="WOX13-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46777">
        <property type="entry name" value="WUSCHEL-RELATED HOMEOBOX 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46777:SF5">
        <property type="entry name" value="WUSCHEL-RELATED HOMEOBOX 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="104"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="2">
        <location>
            <begin position="106"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="206"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0567598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="276" mass="29846" checksum="90546991D1F8E505" modified="2022-10-12" version="1">MESESRLGRMGDMVSMGQPGSGLVLGPSLESSLPQPLYTRGSGQVMTEEQLETLRRQISVYSTICQQLVEMHKASVSQQAALPGMLVGGQISSLDQMTGTPTHKSTARQRWTPSQHQLQILEKLFEQGNGTPNKQRIKEITAELSQHGAISETNVYNWFQNRKARAKRKQQMVTPKDGESEADTDVESPKEKRSKPEGDHIQDEAGGVGDGNGGGSSDGGGNGVPEPRSAKFDQQDATSSALLHPQSDTKPDVSSFNRSAGFDTHNIPQGIPSMMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCS2</accession>
    <name>A0A8T0HCS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G100000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCS2"/>
    <dbReference type="OrthoDB" id="529367at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0038023">
        <property type="term" value="F:signaling receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009725">
        <property type="term" value="P:response to hormone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009744">
        <property type="term" value="P:response to sucrose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="ADIPOR/PROGESTIN RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855:SF132">
        <property type="entry name" value="HEPTAHELICAL TRANSMEMBRANE PROTEIN 4-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="14"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="376" mass="42769" checksum="0FB7E842C91E9842" modified="2022-10-12" version="1">MGADHYDEGRVASVGVTRRRGAGEEGRDEMTTTTSPKGKTLERNLSNKEKAIELWCNVKHQLVEYSALPEYLKDNSFIVRYYRADWSFKHSLYSMFSMHNETFNVWSHLVGFFLFLGLFIYTVVHMPGIVDPETLERWQSGVIMEKLPSYLQLPEALSSCVPGTFDGSRCIQKPITRGPFLVFLVGAMYCMLASTTCHLLGCRSAMTFYTLMRIDYSGIATLIAASFYPPVYYSFMCNPILCNMYLGMITTMGIFSVCASLVPVFQTAEYRNVRAALFFSMGISGIIPCFHKIFLYQDDPMAYQALYNEIYMGIIYAMGALVYATRIPERWKPGMFDIIGNSHQLFHVLVVLGAYVHYRGGLIYLQWRDVKGCPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE64</accession>
    <name>A0A8T0HE64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G119900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035749369" evidence="1">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="80" mass="8922" checksum="323E3615C8183867" modified="2022-10-12" version="1">MRTVVLFCGSRFLSALSAPNALSQLEHTVVNFQVLLENAKQPRTIDNLKDRISCYVQIIPEVTAHELLKKIVVAIELSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF36</accession>
    <name>A0A8T0HF36_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G048800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF36"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000132">
        <property type="entry name" value="caffeoylshikimate esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="57"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="320" mass="35466" checksum="C18C8DECBF8D5A2E" modified="2022-10-12" version="1">MEREPHPCCDATSASIFGEMDPVEFYAKHRVVYIEDTLVNSRKLRQCWRSWVPEGGRVRGVVCVCHGYGADAGWLVQLSCIAIAKEGYAVYAIDHQGHGKSEGLKGHIPDLNAVVDDCIAFFDPKRGSHKGMPCFLYGESLGGAIALLIHLRQPEVWQGVVLNGAMCGIGKFKPPWPAEHLLALVAGFIPTWPIVPTKDIPTISFREPWKRDLARNNPNRYPGKPRAATAQEFLRVVKEIESRASQVTAPLLILHGDHDVVCDPDGSKMMYQNAGSKDKTLHIYPGMWHQLVGEPAEGVEQVFGDMFAWLEAHLPTQAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFA4</accession>
    <name>A0A8T0HFA4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G082000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFA4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035773520" evidence="1">
        <location>
            <begin position="26"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="10606" checksum="DE9B0D3B5C502A0B" modified="2022-10-12" version="1">MLTTRGSTILLALMMGFMTLITSEAQPQLRSCCQVPEFGRRQCCFEHPEDRCCGRGGHQTPPPPFNRQHCCDSPDIRNCCMSGPPSAIDSCCLDPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFC8</accession>
    <name>A0A8T0HFC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G072100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000322">
        <property type="entry name" value="Probable disease resistance protein At1g63360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.430:FF:000003">
        <property type="entry name" value="Probable disease resistance protein At5g66910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058922">
        <property type="entry name" value="WHD_DRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766">
        <property type="entry name" value="PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766:SF30">
        <property type="entry name" value="TIR-NBS TYPE DISEASE RESISTANCE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23559">
        <property type="entry name" value="WHD_DRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="3" id="KW-0611">Plant defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="NB-ARC" evidence="4">
        <location>
            <begin position="176"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance protein winged helix" evidence="5">
        <location>
            <begin position="427"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="724"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="898"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="977"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="6">
        <location>
            <begin position="1150"/>
            <end position="1232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0569188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1245" mass="140764" checksum="BEBDAE0DA2E7B3D1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFM7</accession>
    <name>A0A8T0HFM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribulose bisphosphate carboxylase small subunit, chloroplastic</fullName>
            <shortName evidence="7">RuBisCO small subunit</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">RBCS</name>
        <name evidence="10" type="ORF">KC19_6G172300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7 8">Heterohexadecamer of 8 large and 8 small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Plastid</location>
            <location evidence="7">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RuBisCO small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009853">
        <property type="term" value="P:photorespiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019253">
        <property type="term" value="P:reductive pentose-phosphate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03527">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.190.10:FF:000001">
        <property type="entry name" value="Ribulose bisphosphate carboxylase small chain, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.190.10">
        <property type="entry name" value="Ribulose bisphosphate carboxylase, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00859">
        <property type="entry name" value="RuBisCO_S_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024681">
        <property type="entry name" value="RuBisCO_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000894">
        <property type="entry name" value="RuBisCO_ssu_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036385">
        <property type="entry name" value="RuBisCO_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL CHAIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31262:SF0">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL SUBUNIT, CHLOROPLASTIC 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00101">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00152">
        <property type="entry name" value="RUBISCOSMALL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00961">
        <property type="entry name" value="RuBisCO_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55239">
        <property type="entry name" value="RuBisCO, small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0113">Calvin cycle</keyword>
    <keyword evidence="6 7 8" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="1 7" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 7 8" id="KW-0601">Photorespiration</keyword>
    <keyword evidence="2 7 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribulose bisphosphate carboxylase small subunit" evidence="9">
        <location>
            <begin position="72"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0570581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="19925" checksum="B81BFA7C503711CF" modified="2022-10-12" version="1">MASIVAASTVVAPAAFAAASSSVGASESTSVKAFSGLKSATLFSAKSQTLSSVQNGSRVQCMQVWNPTGNLKFETFSYMPDLSEQDISKQVDFMIREKLIPCLEFDPVGVISRTNNRSPGYYDGRYWTMWKLPMFGCNDASQVLSEIQECKKAYPQCYIRVLGFDNIKQVQIAGFLVARPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFQ5</accession>
    <name>A0A8T0HFQ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G163300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035830373" evidence="1">
        <location>
            <begin position="19"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="50" mass="5625" checksum="06C149FC6CC16173" modified="2022-10-12" version="1">MSLHLLLFCHCLVNRSYFYANDDGFSVLSSCRGSVYLFHGGLGISHIILF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH82</accession>
    <name>A0A8T0HH82_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G129000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035807489" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6833" checksum="D671B5DCACE662B4" modified="2022-10-12" version="1">MLNMLMWCWFCFLSYRLIECLEVLLQSSCLSFSRPLFECRGWKPIIDLRWRSGLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKG7</accession>
    <name>A0A8T0HKG7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG000600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="160" mass="17788" checksum="ADF948FFEE46F6D7" modified="2022-10-12" version="1">MVWPWAGHGKVQVLPRQSPSLSWEDGGAHATEVCVKTGKTERDAEFEIWRSFETSWVLEGRRPLRDWRRRGRLPLWRALTATPAALWAAAATTPAAGALASASTTITGGLSTHDHHPRRWELLQIFLGFCFAISSAGEFPAKSNHPCLLGLDFLVWISRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL08</accession>
    <name>A0A8T0HL08_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG013500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL08"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="11161" checksum="AD31EF08224E03E6" modified="2022-10-12" version="1">MESEQMRFSLSTECLQVGLQLNNMERYHWRLAFGNSQQPEYCCCRKLVDLSWSHKPLTCSADDPYAMQLAQSLVNNSVQVPTPTLHLPYQVLVILSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLE4</accession>
    <name>A0A8T0HLE4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG028800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLE4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="155" mass="18362" checksum="8549AA05B84721D7" modified="2022-10-12" version="1">MRSTSSQLRLRRCGNQENRCRMLSLEHRRRVKQRIDLMEANIGFPLNDVRRIQARDLKLQYREDMLSDRWHAKDRRNGCRLRTIKCKCCICMGSSWSKRSRTMARKHLENVGRHSFCRGRTEESETTNGHYKENTLAASKHQMNIGVSKSRLPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM57</accession>
    <name>A0A8T0HM57_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG050100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="9004" checksum="B9B6C5C640473987" modified="2022-10-12" version="1">MKRGFRQCFRELCETTYYLQDTPSTNSRPSFLQGFRMSSSHKLLIQLHGGVFTRWQASGSKRSRAMHNADQGCTVLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HND0</accession>
    <name>A0A8T0HND0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG084600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HND0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48258">
        <property type="entry name" value="DUF4218 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48258:SF14">
        <property type="entry name" value="OS02G0583300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="288" mass="33031" checksum="40EDF7584C223F41" modified="2022-10-12" version="1">MRSFFLENADILEPYRLQYAEVTQERANARQQWRSRHYARAGARAPNFPPHLSEIQPFPEWLRDTVQAQILTDMYVDEMVEAISKFPLLVAKKYCSLYSYGYHLRVQSAEEHLKTCDSGIAGTFIRACRAGVGDRNIVVAPVEYVGSLDEIIELDYGIFTQVVLVALWIKANYRGTNATMKRDRWGFTLANFNKIIDFGEDSFALPSHVQQVFFSDCSETPEWRVVIRTEPRGRRVVASATDREEGQLFQLGRDDEFEGLQIPVNISEDLPPRTEEGRVLLRKTCLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNL1</accession>
    <name>A0A8T0HNL1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG078700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054502">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051358">
        <property type="entry name" value="TF_AMS/ICE1/BHLH6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31945:SF144">
        <property type="entry name" value="BHLH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31945">
        <property type="entry name" value="TRANSCRIPTION FACTOR SCREAM2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22754">
        <property type="entry name" value="bHLH-TF_ACT-like_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="6">
        <location>
            <begin position="145"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0572243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="383" mass="43043" checksum="56E3CB339AB42D68" modified="2022-10-12" version="1">MIEKCSLASLYPLHGSIWPDTAVTLKEREDTEMNRVFYSDFKDQVICTTEDTNTVWRLQEFNPAQSNTHRAHKNNEFLELNQMKITRDHSQVPDLPLANEVTRGTVSSLGSKRTKSMTDHNDQDLVEGVGLRSSKVKNQGRASSVHASKNLISERKRRKKLNESLYELRSLVPNITKLDKASIIGDAINYIKELHQEVETIELEISKKENASMVEGSGRSMASDSGENAVKSGAITETGAVTTVNYTIDSQPNHQYFGIEYVENFSEDIDQDQSPAAIDQEQSPAVVDQQKMVEIEIDKLDQKSYLLRVFCQKESGILVQLMDSLESLNANFLSANCTTLEESMMNTFVIEMQEAEIMEIEEVQTIITNVVAEHGLTSVVLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNU8</accession>
    <name>A0A8T0HNU8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG109200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9221" checksum="D1DFEB5F82F36813" modified="2022-10-12" version="1">MSPIVGIPPRAWTLSRISIANCTSFSWDQSSGTRSRISCSQVQPQTSAMVYSSDASIPLSFNIVIFSPRLKPSHSPTSLSSSFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPA7</accession>
    <name>A0A8T0HPA7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG123400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000117">
        <property type="entry name" value="Monoglyceride lipase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051044">
        <property type="entry name" value="MAG_DAG_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11614">
        <property type="entry name" value="PHOSPHOLIPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="221"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="486" mass="53644" checksum="A048349A864CA22A" modified="2022-10-12" version="1">MSMSGHQDSSAAITSCTHPAIFYTIAPECSSQSFLHHTTISEWQRRGVFRGSPMSLMAAPRTVYARNPAAESAIRVEKQGAPTSVLHYFSPFILGSFPLRALRGLAMAFNSLSAMAPSSFHLNAIRLAMLKKDEGDESQSDESVVEGESSESQPRLPLLWFPRFGRSVKEINEVQKRREIAMKRMIESEETERKVVPFVNARGQTIFTQSWTPANPRVDLKALVILLHGLNEHSGRYAEFAMHLNGQGYGVFGMDWIGHGGSDGLHGYVESLDHVVADAQEYIQRVRAEYPGLPCFIYGHSTGGAVALKAAFQPEAVESLEGGVILTSPAVRVKPAHPVIGAVAPLFSVLLPRYQFRGANRKLAVCRDPAALVTKYTDPLVYTGSIRVRTGTEILRLSCYLLKNLKTVNIPFLVLHGSDDQVTDPKGSQELYDQASSPHKNIKLYTGLLHDILFEPEKFEIIQDIVQWMDDRLALINVGDGLIADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPF0</accession>
    <name>A0A8T0HPF0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG127200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPF0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="7014" checksum="32672E5D5590FA6C" modified="2022-10-12" version="1">MSSWRHCDGRFQCILRYVNSWLKCIKRVCRSKQPFLLFADNANEYGIRAKLKIMISGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPL6</accession>
    <name>A0A8T0HPL6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG132500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="148" mass="16607" checksum="B14BC83254504B1D" modified="2022-10-12" version="1">MDYSTMAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRCHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQHQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQS4</accession>
    <name>A0A8T0HQS4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG133700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQS4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008889">
        <property type="entry name" value="VQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039612">
        <property type="entry name" value="VQ_5/9/14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33783">
        <property type="entry name" value="PROTEIN HAIKU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33783:SF1">
        <property type="entry name" value="PROTEIN HAIKU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05678">
        <property type="entry name" value="VQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VQ" evidence="2">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="29873" checksum="F065B0667527E311" modified="2022-10-12" version="1">MAAPISVDFGEAGEGGKVGNKSLAVNKSSTKIKKGLRPMLAQPRLAPTVYKTEPSDFRSLVQKLTGTSQTIATSPPCGPKPPNSRLQRIAPPPLRPTSTYLSFGHSACPSQSACAQLESEPVTYTSPSGNQLFPLSSFSSLPKHVTSPFPVSPLSFSPLPQLSPSDQGWVNSLNGLESPGSVVIRQLAQSIVEGNVLSSKQEQATRAAATATSSLPPVSPNFSSLRFSSSAFGLLSPSGFPSPSRFGFGLGNVYGISGSFTPSAALSMDATFSFPEPDIAMSPTSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR21</accession>
    <name>A0A8T0HR21_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG172900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR21"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="10800" checksum="1D70BC741ABFAE33" modified="2022-10-12" version="1">MIGPDENPLGKTRALKRSKTDGIAQDSSLVGNLSRDSSGVQEGEESSGKGKRKAASKKTSSKKGTSEEQLMSPKNVDAPEDVLSPPRASKREPRLKKHKGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSN2</accession>
    <name>A0A8T0HSN2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">VTT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG226700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSN2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="VTT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="GOLGI APPARATUS MEMBRANE PROTEIN TVP38-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677:SF24">
        <property type="entry name" value="OS07G0655900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="VTT_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="VTT" evidence="7">
        <location>
            <begin position="102"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0573982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="34615" checksum="D962644D4BF4A200" modified="2022-10-12" version="1">MKVVKLATSAKLRVHLAGKRPSLDIDRKGRRWRVNMSTRAWRLLLTITAILLSLGVGIQLPQFSHYVEQTLKQFLIWVQNDAGAWGPIILALAYVPCSVLAIPASILTLGGGYLFGLGVGFVTDSLGSTLGATAAFLVGRTIGRTYVTSKLKDYPRFQAIAIAVRKSGFKIVLLLRLVPLLPFNVLNYLLSVTPISIATYVLATWFGVMPMTLAFVYVGTTIKDIQDISHGGAHFTRARVIMLSVGFAATIVVAILVTRIAKDALRTAIEESGSENDMGLVADDESDVRQPLIVRIDSMNGTDGAQASQYPISRVESVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTK4</accession>
    <name>A0A8T0HTK4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG240800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8141" checksum="88A9A4DC15675323" modified="2022-10-12" version="1">MSIAVMKANVLPKPARNKSGILEVSAILADRLVETFVFTLLSSFLLHSVISFTCWHRFYFLLTECSELTWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUW0</accession>
    <name>A0A8T0HUW0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG296000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUW0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5840" checksum="2F8ABCDEAD552899" modified="2022-10-12" version="1">MAAGMESVAVDDQESNAELVLFQVKECYVCMIPPRKSAASYKADEWDINKWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVM5</accession>
    <name>A0A8T0HVM5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG271900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="9856" checksum="ABFBAF2AA6CAA46C" modified="2022-10-12" version="1">MLAFPLPASALGALDCERSPVPSMFAAGIAPFKWCQTNSRSSPRSHVSCARHSDSPGGSTLLGAGGGHFLGGSNGEVDAVFFLDVAAYSCKTSAHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVT3</accession>
    <name>A0A8T0HVT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Integrase core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG294400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058913">
        <property type="entry name" value="Integrase_dom_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791:SF5">
        <property type="entry name" value="CLR5 DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46791">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24764">
        <property type="entry name" value="rva_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase core" evidence="1">
        <location>
            <begin position="3"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="19523" checksum="E792B676E4DB30CE" modified="2022-10-12" version="1">MFGIWIHGCIDGVSHYVLYACVASNKTQETLFEPFSVDVQKFGPPLRKRSDFVAEHALIKRYMEEVRPATSNPFLMGSSVHNQRIEYWWRLLWEEIVWYHKNAVQEMVDQGYFIPDDLYHRISFQDVYIPILQEIINEWIGTWNLHRVQLIDEQGRFRPSHVPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW13</accession>
    <name>A0A8T0HW13_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG312300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="534"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="745"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="148"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="197"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="354"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="753"/>
            <end position="763"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="786" mass="88669" checksum="6D2B19D43B56E3D7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWH5</accession>
    <name>A0A8T0HWH5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG312000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="234" mass="26457" checksum="C85B28134270BDD3" modified="2022-10-12" version="1">MNHTQKFIVLWSRMEMVRMLVKWVALSASLSSRAWGHFLPLDQCDFYFQGHKETAPMLDVMVTRNLTASPPILTIGDMEVVAAEIGAECAFLPDPSMVFEKRSCTGHFHVRNHHLSGRFASEEFASLEAFRFHQVLLALESAELADGTLLDKNDTNVEYRRPRRCVTFLTTPAIIPHYNSGTGIQRVDIITRIVDLVPKMLNKAHRKKLNKITTSMEQVGRDMGVLAQSVADFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX05</accession>
    <name>A0A8T0HX05_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G020500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="209"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="452"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="62"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0575650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2055" mass="225749" checksum="6246018455AC9BC5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZE3</accession>
    <name>A0A8T0HZE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">O-methyltransferase dimerisation domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G058800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZE3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012967">
        <property type="entry name" value="COMT_dimerisation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11746">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08100">
        <property type="entry name" value="Dimerisation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="O-methyltransferase dimerisation" evidence="1">
        <location>
            <begin position="34"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="22038" checksum="2ACB80B053538E9D" modified="2022-10-12" version="1">MAGWDAMTMLSKTGAAAQDGRRPPQSAMDVLSPLLFGHAAAMTLKAAVELNIPDILARAEPQRHLSVHEIAAELPSGSVDELSLHRVMRALVHLGVFSADQVESHSSEPLARYGLTPASRMLVRENNPGSLAPMVMYLNYKSSQTPWQHLHETILCGKNPFKVAYGKVRTHQFLDGSSSDSLRNKGLGLAFVVLNAQRCCLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZI1</accession>
    <name>A0A8T0HZI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G090700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="152" mass="17646" checksum="F28EEADCD352B181" modified="2022-10-12" version="1">MRNQHQLPTYYNHLKQKEFSSNAKSDITRLHSTSLKQSNAIIHKKYQKHTGGAEIIYQHPSKDNTNKLDHKATHGTNQEVEIKGGSKRRVTVHSIDKYCTHNGNHKVSFSKPYSLQFQQLLHLKWLIITTACKKKNLQNIYHTGRAHDDKHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I015</accession>
    <name>A0A8T0I015_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MHD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G106000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I015"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd09257">
        <property type="entry name" value="AP_muniscins_like_MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036168">
        <property type="entry name" value="AP2_Mu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028565">
        <property type="entry name" value="MHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018808">
        <property type="entry name" value="Muniscin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37769">
        <property type="entry name" value="OS08G0243900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37769:SF1">
        <property type="entry name" value="OS08G0243900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10291">
        <property type="entry name" value="muHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49447">
        <property type="entry name" value="Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51072">
        <property type="entry name" value="MHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MHD" evidence="2">
        <location>
            <begin position="404"/>
            <end position="656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="656" mass="69458" checksum="07FF9588928FC751" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0D6</accession>
    <name>A0A8T0I0D6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin-like RBCX protein 1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G116300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0D6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110102">
        <property type="term" value="P:ribulose bisphosphate carboxylase complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.210">
        <property type="entry name" value="Chaperonin-like RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038052">
        <property type="entry name" value="Chaperonin_RbcX_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003435">
        <property type="entry name" value="Chaperonin_RcbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33791:SF12">
        <property type="entry name" value="CHAPERONIN-LIKE RBCX PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02341">
        <property type="entry name" value="RbcX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158615">
        <property type="entry name" value="RbcX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0120">Carbon dioxide fixation</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0576900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="317" mass="35303" checksum="E98E350488807222" modified="2022-10-12" version="1">MCTCCCMRWFLRLGSKGDGRSKGGRSQEPGATTGLSCVCSHGFRFQPQSESESRSEARPREVELDAKTSSLHEFAAVGDVLLPGGWCWNAQFWAGCLNSVVILVCSHLRTMATAMRSTGCCAIANTASLRQTQNTSKQDRWKRSSSTGCRTGAMLVPSATGLTSELFCNKKCFMPKNGSRRNFRVGRVNPIRSKMFVPGFGEASPEAQAAAALHNFFTYVAVKIVASQLEDYNKEAYVDLMDFLEKTPLKDGDKFIAQLMRESFRHKNLALRIMEVRSAYATQDFEWDNLQDLSGKQIEKANTALMREFLTETSNME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2F9</accession>
    <name>A0A8T0I2F9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit epsilon</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G168700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasmic vesicle</location>
            <location evidence="2">COPI-coated vesicle membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the COPE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2F9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000140">
        <property type="entry name" value="Coatomer subunit epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006822">
        <property type="entry name" value="Coatomer_esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10805:SF0">
        <property type="entry name" value="COATOMER SUBUNIT EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04733">
        <property type="entry name" value="Coatomer_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016478">
        <property type="entry name" value="Coatomer_esu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00025582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR016478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0577634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="31891" checksum="E1FDA78B9AFA61B4" modified="2022-10-12" version="1">MSGPDVLFPLRNNFYLGAFQAAINESNVRNLSDADATEKDSFVYRSYIALGQYQLVIDEINDSAPTALQAVKLLALYLSGGAQKDKALSGLSEWLSDTAVSSNPTLLLIAGMIYTHEQNYNEALKHTHVGGTLDLCALNVQIYLKMHRADYAEKQLKIMQQIDEDHTLTQLANAWVNLSLGGAKVQEAYYIFQELCEKYTRTVMLMNGSAVCQMHMGQFEDAEASLLEALNKDSKDANTLANLIVCSLHLSKPTARYLSQLKITHPNHVLVERAAAGEASFERAVQSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I394</accession>
    <name>A0A8T0I394_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G143000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I394"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="11297" checksum="090074528E965C8B" modified="2022-10-12" version="1">MGLCLARSIQRVRAGAHSAMSFSRILWLTGICFYMRISPARSLHWSSPLMIMWMPGRLEYTRRPVMRSVIGSLYHVIHLKNSRASPLLFRIWLLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4C3</accession>
    <name>A0A8T0I4C3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G190900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4C3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="13870" checksum="E856DA1F4E0FA4B7" modified="2022-10-12" version="1">MTRKHDSARTTGADPKPDQNPNCQLWSMLPDLHHELDSRSRRAPRALGRRGGGSERGVGRGGASGELWRWRRNLGLPTYWLLDNRASGSASGRPRPGDSPGEGPLPRVPPAPRDPPGRRLARESRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I835</accession>
    <name>A0A8T0I835_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G034700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I835"/>
    <dbReference type="OrthoDB" id="651283at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11454">
        <property type="entry name" value="bHLH_AtIND_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.280.10:FF:000022">
        <property type="entry name" value="Basic helix-loop-helix transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045843">
        <property type="entry name" value="IND-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914:SF59">
        <property type="entry name" value="TRANSCRIPTION FACTOR BHLH83-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45914">
        <property type="entry name" value="TRANSCRIPTION FACTOR HEC3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BHLH" evidence="7">
        <location>
            <begin position="449"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="22"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="22"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="64"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="151"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0578583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="538" mass="58622" checksum="6B2AEF2A93DB946A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICR1</accession>
    <name>A0A8T0ICR1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G188300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICR1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF148">
        <property type="entry name" value="ATMRK SERINE_THREONINE PROTEIN KINASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="399"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="180"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="56"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="235"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="698" mass="76895" checksum="185AC2627FEB645E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICU7</accession>
    <name>A0A8T0ICU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Actin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G200900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the actin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICU7"/>
    <dbReference type="OrthoDB" id="503831at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048767">
        <property type="term" value="P:root hair elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd10224">
        <property type="entry name" value="ASKHA_NBD_actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000291">
        <property type="entry name" value="Actin, alpha skeletal muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000001">
        <property type="entry name" value="Actin, muscle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000404">
        <property type="entry name" value="Major actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000058">
        <property type="entry name" value="Putative actin-related protein 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004000">
        <property type="entry name" value="Actin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020902">
        <property type="entry name" value="Actin/actin-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004001">
        <property type="entry name" value="Actin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11937">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00022">
        <property type="entry name" value="Actin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00190">
        <property type="entry name" value="ACTIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00268">
        <property type="entry name" value="ACTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00406">
        <property type="entry name" value="ACTINS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00432">
        <property type="entry name" value="ACTINS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01132">
        <property type="entry name" value="ACTINS_ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="377" mass="41579" checksum="5618696731A2D6A6" modified="2022-10-12" version="1">MADGDDVQPLVCDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDALMKILTERGYSFTTTAEREIVRDMKEKLAYVAIDFEQELDTARSSSSLEKSYELPDGQVITIGAERFRCPEVLFNPSLIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWIAKAEYDESGPSIVHRKCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID56</accession>
    <name>A0A8T0ID56_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G243800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015185">
        <property type="term" value="F:gamma-aminobutyric acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015180">
        <property type="term" value="F:L-alanine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005313">
        <property type="term" value="F:L-glutamate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015189">
        <property type="term" value="F:L-lysine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45649:SF30">
        <property type="entry name" value="AMINO-ACID PERMEASE BAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006060">
        <property type="entry name" value="AA_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0581342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="57489" checksum="4048EF197D197179" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF22</accession>
    <name>A0A8T0IF22_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">rRNA adenine N(6)-methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_4G225200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6 7 8">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000007">
        <property type="entry name" value="rRNA adenine N(6)-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727:SF7">
        <property type="entry name" value="DIMETHYLADENOSINE TRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 8" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 7 8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribosomal RNA adenine methylase transferase N-terminal" evidence="9">
        <location>
            <begin position="91"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00061109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0581103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="44243" checksum="3338C81833C54180" modified="2022-10-12" version="1">MNVCLGAAGRSLGRCRGRLVIQAVQGSLLPASDFHQRAGNSPSISKGIDERWDDTAMAGGKAVKGKPAPQRFQGIQFQKSKGQHILKNPLLVQSIVQKAGLKSTDIVLEIGPGTGNLTMKLLEVCKKVVAVELDPRMVLEVTRRVQGTPYANKLQVIQGDILKTELPYFDVCVANVPYQISSPITFKLLSHRPLFRCAVIMFQKEFAQRLVAQPGDSLFCRLSVNTQLLARVFHLLKVGKNNFRPPPKVDSSVVRIEPRNPLPPINFKEWDGLIRLCFNRKNKTLGSIFRQKAVLALIERNYKTFQALQEASGSEVPAVDPSILGDLAEDHSMEVDMNADGDGMEVEEEDGQQGNAYFKEKCLAVLAEGNYEDKRSSKLTQDDFLRLLALFNKSGIHFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG51</accession>
    <name>A0A8T0IG51_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G079200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG51"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12458" checksum="2A445AB593B0CAB8" modified="2022-10-12" version="1">MAYLDVRQPGSPVGSLRNFGMRCERDHGFPCNEVENEEDDSEVSHQSVHSRVTHLVEDGQFHLFDRDLESEDPSGSCKLGGAPCILPELTQAIQLFKLSALGTIRLNYQHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJX3</accession>
    <name>A0A8T0IJX3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G082200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47418">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="138"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="396"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="396"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="539" mass="58364" checksum="5D6B7C10A8E04EB7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INL2</accession>
    <name>A0A8T0INL2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G004000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INL2"/>
    <dbReference type="OrthoDB" id="1913782at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="402" mass="45709" checksum="78527E2D5140F66C" modified="2022-10-12" version="1">MGAGIVTRDCKALHAEVSDRCDERCWGRQWLSGMWNSTQMSGQQLRGSSFALTEATLDDEAVESVLAASTSGRVDFTFWNERRKRRRRAWSSPTGVLYVVNRPNDFLYCELEQGRKLEENVSIDMKHSVSTCFEQGRLGEDKSILMSTSHKLDACNMLTTHYVNNLKGGEEFSCNSSHSIRPASRLSTCFHSASIGDPTLEVELEHESETKKISETFLANLRTGERLLRLQSKNVINDSVAFSNTYITNLRGQHSVRLEAALPVWGFANISKSFTTDFQQSHQFCLKAQQRIGEQNTIRTAFIRNLHHNNQISVELKHVAQGRRDVAVNLTSDLHGSTQFKVTSSHIRQANCWGWTFRKVFGEAHLIGVEWKREVAPDKFLLLRTSTQDRVCTVYAELRRPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISZ9</accession>
    <name>A0A8T0ISZ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G076300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11614" checksum="8351794F82526CD5" modified="2022-10-12" version="1" fragment="single">VTSTRWCRLKRSSLLSHLVDENEYLPRENNIRDVKRHRPTSHGTYLQSERAMETADECKKSSRISWIVVSPVPNYFSDKSTVSNSPTNLKNRSGLIPVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITY7</accession>
    <name>A0A8T0ITY7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G077200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITY7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5538" checksum="178DB2EEF29C98E4" modified="2022-10-12" version="1">MSWFIILKVRTTWKLALIRNTEVQLVAGIVSCYNPVKVGASRRLHSLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU86</accession>
    <name>A0A8T0IU86_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G154400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035747314" description="NADH dehydrogenase subunit 1" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="49" mass="5538" checksum="07A3DBE8BD5C82AB" modified="2022-10-12" version="1">MWIVCGLFVDFLCIVCRLCVDCVWIECVGHIGLKQLSIGRGMDSVEYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUX1</accession>
    <name>A0A8T0IUX1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G092700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUX1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004158">
        <property type="entry name" value="DUF247_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31170:SF25">
        <property type="entry name" value="BNAA09G04570D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31170">
        <property type="entry name" value="BNAC04G53230D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03140">
        <property type="entry name" value="DUF247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="494" mass="56068" checksum="C721036F2B6009BB" modified="2022-10-12" version="1">MMEESILEMARQQLKHGNQHQALQVDTAECTIFEVPGLVRAKSPTSFQNKGIELGLHYRTLKKSQIEIFKIEIAQVLHSKLVKGNSSWDHFAQKVLGDVSIARRAYGVSSAKFSDEEVQNLLALDALFLVVFWKFVNGGRFFLKEFEAIAGRLKEIVSGIDKTDFFLIENQVPMYLLQSVVRQLCETDEKTEARRVSDPSFLDTKVEDELEMILYAAVIHLNPFKYPENTRSVTLHGCLNGSFCSQQIPKNSRQRLHQYLKSAYPIEPLEKSLINCQHLLDCLYRVVCGHLLPFKAEKHFNSDIELENIPTASRLEAIGVRVVGTAPTLNDIKLSGSGYLRSAKLELPKVALYDYSAAAFHNLALHEQLALGGQSGELRCYLKCMACLCTNASDLRVLSEQGVIDSHITSKDTVIDIWDQTRKGIFTPLSLPSNWVKCNRRIHQHRNARLKRWRQECWTLFFAKPWTLVSVLAAIILLFLTATQAWCAVFPRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWK2</accession>
    <name>A0A8T0IWK2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G216100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWK2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9832" checksum="4406942D6D2B524E" modified="2022-10-12" version="1">MDTVQFSLKKASKLVKAIGGKMATDRCIKFFLFLIAVGIVAIITVKVIFSTYRYLSNTSLYADFNIFAPGGREVLLAGLYEGVGGCVDRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWV2</accession>
    <name>A0A8T0IWV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G174800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01285">
        <property type="entry name" value="nucleoside_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079">
        <property type="entry name" value="CYTOSINE DEAMINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11079:SF149">
        <property type="entry name" value="TRNA-SPECIFIC ADENOSINE DEAMINASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="Cytidine deaminase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="40"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0587582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="234" mass="25414" checksum="03BE2894F6B2163B" modified="2022-10-12" version="1">MGDNVVCNELEGTTTQDLEDDRFLEQNGLGSRSVTTAAGNSVMNFMKLAFAEAKGALARLEVPVGCVIVKDGEVIGRGSNRTNETRNATRHAEMEAIDMVLCLWQQSSTAHSDNVSTEGFQQCDLYVTCEPCIMCASALSLLGFRKVYYGCGNDRFGGCRSVLDIHTDGCAPCGLSYDQAEVHEVQKTRGFECVGGLMADEAVALFQGFYENGNQNAPRPHRPVRIEKSPQLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXK3</accession>
    <name>A0A8T0IXK3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G167300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXK3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035922284" evidence="2">
        <location>
            <begin position="25"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8091" checksum="C92785A8A545D8F0" modified="2022-10-12" version="1">MRPCLGIDVSLCLLFLFGVESVVACFDDLVLSILNLHFQFANFNLLFYSEISTIASIFSVTCFGKFLLTMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY32</accession>
    <name>A0A8T0IY32_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G199700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11578" checksum="68D70E19F75B22D6" modified="2022-10-12" version="1">MLSRGDAVASSTVMHRHLTLLDRQKRKRDEFTEDGRSVPPPHFLCLYHSHWWYCACESRSYTTVPSLLHRSRGARGPGPSTSIIASRSHQSKFCETMECMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYP4</accession>
    <name>A0A8T0IYP4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G216700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050655">
        <property type="entry name" value="Plant_B3_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920">
        <property type="entry name" value="B3 DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31920:SF122">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="65"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="319"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="47224" checksum="35801776F367246A" modified="2022-10-12" version="1">MRFFFKDSPERGVAQMGSSHGNLSEVLNELEGKMCFVKEMTSSCVWPLDPEGRIHRGRPYSKCQLLLPRHFARAHKMVNISRICVVVHSGNTKKSWSLRLSHYPSRGETAIISGWGQFVTDNGVAKGDRLVFSLTAMPKFRVYIFDSNGLPKAPQMLQPSSFPTEIKVSRRIHRVLESLRNKREDSTAEGTENLVSMSSVPRSKRKAISDDESVDLTSNAASLNTFHRSARPTKAEIVEDSPLKTCAQCSYPFKQDTHVKKEPLSKEEELVKEEILFDREEFVMPFTKKSKEGTSDRNLNLSQKSKIHAPPTAEHLLQTASFQKQLAKGNLSRMEIPAAFVKEYGSRFQTRVQLQGTLELSPVRDVGCFCYGFAGQFRCFFKKGWQDFVSDNMLREGQNIIFTLTANSVFKVRVVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J184</accession>
    <name>A0A8T0J184_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G259500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Nucleoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the exportin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J184"/>
    <dbReference type="OrthoDB" id="27218at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009846">
        <property type="term" value="P:pollen germination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009860">
        <property type="term" value="P:pollen tube growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000055">
        <property type="term" value="P:ribosomal large subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000056">
        <property type="term" value="P:ribosomal small subunit export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000022">
        <property type="entry name" value="protein EXPORTIN 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041123">
        <property type="entry name" value="CRM1_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041235">
        <property type="entry name" value="Exp1_repeat_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013598">
        <property type="entry name" value="Exportin-1/Importin-b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045065">
        <property type="entry name" value="XPO1/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014877">
        <property type="entry name" value="XPO1_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040485">
        <property type="entry name" value="XPO1_repeat_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223">
        <property type="entry name" value="EXPORTIN 1/5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11223:SF2">
        <property type="entry name" value="EXPORTIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08767">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18777">
        <property type="entry name" value="CRM1_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18784">
        <property type="entry name" value="CRM1_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18787">
        <property type="entry name" value="CRM1_repeat_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08389">
        <property type="entry name" value="Xpo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01102">
        <property type="entry name" value="CRM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="36"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0588651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1072" mass="122512" checksum="7DD3EA6E45954128" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2D3</accession>
    <name>A0A8T0J2D3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HVA22-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G292400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2D3"/>
    <dbReference type="OrthoDB" id="10009287at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004345">
        <property type="entry name" value="TB2_DP1_HVA22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300:SF176">
        <property type="entry name" value="HVA22-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12300">
        <property type="entry name" value="HVA22-LIKE PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03134">
        <property type="entry name" value="TB2_DP1_HVA22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="291"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="13"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="36693" checksum="80A57F1550575564" modified="2022-10-12" version="1" fragment="single">SPLFASLRSSSPRSPPPLPSPALPSPFPSPPLPSSPLLSSPLLLPCVPCSWIVSSDPSLPPSHACIHACIHPSVAPPPPPPDLGLPRIITGLAILTILLLLSPSPSPSLAYAPPALAMAAAVSALGGELGLRLLLTPAASHVIVRTACTVVGIGFPIYSTHKAIESQNHTEQEEWLVYWAAYGCFSVAEVFSDKLLSWCPFYYHAKFVFLVWLQLPKNYGARHLYTNLLRPLLLKHHVRLDRIVDGTRNEMNKFIVSHQHEVQAVQRMLKKFSILVYQAAQDALQSARALEGGANPVGTRSSQDSSTPPPPPSPSDSAYDESTDDAGWIYTDHPRQSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2Q1</accession>
    <name>A0A8T0J2Q1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G014800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2Q1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="64"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="252"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="306" mass="34835" checksum="C7D797EBD6424AC6" modified="2022-10-12" version="1">MLRIATELAVVASVQMLGEISDINTPYSRVLRTILQNLEQAIYSNYVTPHTEGTFDQVPYFELVDKLEAQNQKMLEEQQRWKVIVKEHKSAADGIQEHMEDLNDLLLKEKAKVAELQHDLLIAQKSLRKVTEKAKDLDHKVEQSRALVFDASNIKQKYEEMVEKHDNVQARYIELTKEVQRLQQNLAAARQEAADGVRKSKYNALHDELMNTQSLLQKAQKYERQAQTYTPRPNWPQIRGGPFIGFPTTQQAAEIVNENKELMERNLRLEAEAATLAVALAEAQQPKAPPEKKGKGKGGKGKGKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2Z0</accession>
    <name>A0A8T0J2Z0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G058000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2Z0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008390">
        <property type="entry name" value="AWPM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294:SF5">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05512">
        <property type="entry name" value="AWPM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="20328" checksum="509A8F2FF53D6002" modified="2022-10-12" version="1">MAFGAGSWGISCALLAVNSVMTIIIAGIAGWAFNRSVEHVLCMTDFQDNVEGAAVASHFLPLALVASVVGMGSILAGIYHLRVWRTDTLAAAVSVALVAWLLSLLAAGVALKEIHVGGPRSSKLKVVETFTVLLPLFEFYYLLSLHAAVLFNGREGQGTPHATDSQTQTPITLPELPDVVVEEGLDHFMGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3W2</accession>
    <name>A0A8T0J3W2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G086900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3W2"/>
    <dbReference type="OrthoDB" id="256333at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05285">
        <property type="entry name" value="sorbitol_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000068">
        <property type="entry name" value="Sorbitol dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045306">
        <property type="entry name" value="SDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161">
        <property type="entry name" value="SORBITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43161:SF27">
        <property type="entry name" value="SORBITOL DEHYDROGENASE-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="9">
        <location>
            <begin position="29"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="369" mass="40197" checksum="65B699F414279282" modified="2022-10-12" version="1">MAPAVGSKSDDDQLQSTGRQENQGAYVCGINDLKLRPYKLPESLRPEQVRVRIKAVGICGSDVHYLKYLKVGAYEVKEPMVIGHESAGVVEEVGSQVRHLAPGDRVALEPGVPCWKCSFCREGLYNLCPDMAFFATPPVHGSLADQVVHPAELCYKLPDGVSLEEGAMCEPLSVGVHACRRAQVSPETRVLIIGGGAIGLVTMLVARAFGSPRIIVADTHSERLTSAKEMGADETVLVSRNPEEMEKEIEEIRKKMGGPIDVSCDCVGSTKSLTTCLEITRSAGRVCVVGMRETDMTLPIITAISREVDILGVFRYRNTYPLCLDLIGSGRVDVKPLITHRYKFSEQDIKDAFEMSANGGNAIKVMFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J464</accession>
    <name>A0A8T0J464_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G062900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J464"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015187">
        <property type="term" value="F:glycine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904983">
        <property type="term" value="P:glycine import into mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46181:SF3">
        <property type="entry name" value="MITOCHONDRIAL GLYCINE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="4">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0590002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7706" checksum="0472AD63837F5492" modified="2022-10-12" version="1">MIRTRLQLDRGHQTGIVSTVKHIVEVHGLKGLFVGVVPRVGRRALQQAFAWTIYEDIVVETTFQCCLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J644</accession>
    <name>A0A8T0J644_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <ecNumber evidence="4">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G085600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J644"/>
    <dbReference type="OrthoDB" id="184182at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.170.8.10:FF:000001">
        <property type="entry name" value="Phosphoenolpyruvate carboxykinase (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.449.10:FF:000009">
        <property type="entry name" value="Uncharacterized protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.8.10">
        <property type="entry name" value="Phosphoenolpyruvate Carboxykinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006820">
        <property type="entry name" value="PRK09344.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006821">
        <property type="entry name" value="PRK09344.1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031:SF0">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE CARBOXYKINASE ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="PEP carboxykinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53795">
        <property type="entry name" value="PEP carboxykinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="56"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0590263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="655" mass="72531" checksum="ABB22DF20D068783" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J761</accession>
    <name>A0A8T0J761_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G127600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J761"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10538">
        <property type="entry name" value="SET_SETDB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.850">
        <property type="entry name" value="Histone-lysine N methyltransferase , C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043017">
        <property type="entry name" value="WIYLD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018848">
        <property type="entry name" value="WIYLD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46450:SF24">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUVR4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46450">
        <property type="entry name" value="INACTIVE HISTONE-LYSINE N-METHYLTRANSFERASE SUVR1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10440">
        <property type="entry name" value="WIYLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00468">
        <property type="entry name" value="PreSET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50867">
        <property type="entry name" value="PRE_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pre-SET" evidence="8">
        <location>
            <begin position="850"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="946"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="9">
        <location>
            <begin position="1091"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="74"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="152"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="624"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="679"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="732"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="178"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="682"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="770"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1109" mass="122314" checksum="5B060723749B6BF1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7S1</accession>
    <name>A0A8T0J7S1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Transportin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G128400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="9">
        <location>
            <begin position="65"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="IPO4/5-like TPR repeats" evidence="10">
        <location>
            <begin position="112"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="324"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF25780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0590811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="43507" checksum="B1AB1B7BAD73AB57" modified="2022-10-12" version="1">MHFSLHVCVQLVIVDNMKLCFNTALIVSWGFDLKLMEWHTMVVTVKKLDMHAREFNLEKTMLLQGDAVNIRQAAGLLLKNNLKSSYSLVHPLHIQYIKAEVLPCLGSPDFGVRSTVGTIVSVVAQQGTFQGWPEALQALVQCLDSNDYNHMEGALGALFKISEESPEIMHMDVGGLLERPITVFLPRLLKFFTSEYALLRKLALGTFNQVIVLMPTVLCNHIESYLQSLFSLANDNSPDVRKLVCAALVQLLEVQPTVLKPHMRNVIEFMLQANKDSDKDVALEACEFWSAFCESQLPTDLLREFLPPLIDNLLDNMAYAEDDEALQDDDENKNVPDRDQDIKPRFHQSRFHGDGGAEDDEVVSLEGNLSMLAHSFIPGVNSHQLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8X5</accession>
    <name>A0A8T0J8X5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G228800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8X5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426">
        <property type="entry name" value="ACYL-COA N-ACYLTRANSFERASES (NAT) SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47426:SF3">
        <property type="entry name" value="GCN5-RELATED N-ACETYLTRANSFERASE 6, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="126"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="298" mass="32896" checksum="A03D0124F2143F15" modified="2022-10-12" version="1">MEGSFMLVSGSLLLVPKFVPSGLSSVSARRPIWKGIGQELGRTSLGWRFCSDRGFLREGFDRGGSGLRIGSNGGARPMLPKVFACLESLDSDNELLSFQNDSSAMYERFDIREARLEHEFKGAAWLRADAYSEQQSYTRYVDSFKKKFAEQEFSALKRRISGQPGSYICLVAVSKVLPKDAVDLTWQDGGKETRVLGTLDVSLHHPSPGEAFGGQGLPYGYIANVCVDKSLRKQGIASTLMESAVQVGRKWGLNAIYVHTHATNNPAYKLYLKKGFEVIQSGSPQNLVDGNLLLRLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBE8</accession>
    <name>A0A8T0JBE8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dof-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G304800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBE8"/>
    <dbReference type="OrthoDB" id="1927254at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045174">
        <property type="entry name" value="Dof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003851">
        <property type="entry name" value="Znf_Dof"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089">
        <property type="entry name" value="CYCLIC DOF FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089:SF22">
        <property type="entry name" value="CYCLIC DOF FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02701">
        <property type="entry name" value="Zn_ribbon_Dof"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01361">
        <property type="entry name" value="ZF_DOF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50884">
        <property type="entry name" value="ZF_DOF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Dof-type" evidence="9">
        <location>
            <begin position="50"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="95"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="306"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="282"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="307"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="332"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0593097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="380" mass="40843" checksum="15858DD78E25123C" modified="2022-10-12" version="1">MHLPASKDGTSLGTPLEKLNANRKVVSVDGTPASPSSPSKTAREKPQKVLPCPRCESMNTKFCYYNNYSVNQPRHFCRQCQRYWTVGGTLRNVPVGGGSRKKNRHQRGEPYLRTGPAGTGSPLAMATPGMVPPLGAFQHPLPHDMTGFNFSQLPGFVPQNHPFGGGAFPMDQSSQPMPGMYINPLSNKPGGQQEFPVMQPMYGAMNPHAQAVGASFYPDLGALQLEHQNPGGGGVKAEFWGNHHVMQSQGGNGNGNQAQMNQGLWEQSKQASGGEDQVGAKTGNSASLQTKSGGYESSMLLHLGLNSRPQMNGKSAAWNNNQDHTRGGHPVNGTSPPHGSSTIEEEGSTPTNGYSNSGYEEGDTVSSMWQEMHDMHDIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBJ9</accession>
    <name>A0A8T0JBJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DYW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G285400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000366">
        <property type="entry name" value="Pentatricopeptide (PPR) repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000344">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000031">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein mitochondrial"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032867">
        <property type="entry name" value="DYW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046848">
        <property type="entry name" value="E_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14432">
        <property type="entry name" value="DYW_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20431">
        <property type="entry name" value="E_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="13"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="252"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="353"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="423"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="454"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="524"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="555"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="625"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="656"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="726"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="757"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="827"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="858"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="995"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="domain" description="DYW" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1165" mass="129669" checksum="100F1191681610D5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JES4</accession>
    <name>A0A8T0JES4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G333600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JES4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035877581" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12804" checksum="50AF19D066974F4C" modified="2022-10-12" version="1">MTRILFAVMQLINVVCSEISIVFWMKRCPHNTPWLCITYGARAFKLECRSYALSNTLPVKSQQVLLKNHNSVLSAHETNVTTHPDGNSSGANPQVLLKDFRIRQAECLCLTAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G503</accession>
    <name>A0A8T0G503_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">NADP-dependent glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="6">1.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Triosephosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G053000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>D-glyceraldehyde 3-phosphate + NADP(+) + H2O = (2R)-3-phosphoglycerate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.9" evidence="6"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G503"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008886">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008911">
        <property type="term" value="F:lactaldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07082">
        <property type="entry name" value="ALDH_F11_NP-GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.309.10:FF:000016">
        <property type="entry name" value="NADP-dependent glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.605.10:FF:000013">
        <property type="entry name" value="NADP-dependent glyceraldehyde-3-phosphate dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051020">
        <property type="entry name" value="ALDH-related_metabolic_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42991">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42991:SF1">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035770952" description="NADP-dependent glyceraldehyde-3-phosphate dehydrogenase" evidence="12">
        <location>
            <begin position="20"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="13">
        <location>
            <begin position="96"/>
            <end position="552"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00040853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00042470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00042646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0553975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="565" mass="61311" checksum="44528598BD76770C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6Y2</accession>
    <name>A0A8T0G6Y2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G075500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6Y2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="222" mass="24635" checksum="D13F9CB8ABF66A50" modified="2022-10-12" version="1">MDHGVRESNMEMGLLRNEGTSEPHVDTRSEQGSMEETELSTSSNLLGMTRRSASLSAWGGSNRQQRTPGQAVTTQGSHSEIYGVTSRSYIRMRHKALIVQFNSYAVLLVLLAGAMSVAILQPPGSFDTDGHIRKGAQLYLFMASMSFLFAIMGLFAVMIVFLNLFRPEFNAPPRTDDTLDGSATSREVEIMEVIARGLVRVYYYLGAVVIFHKVLNMSRDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8G2</accession>
    <name>A0A8T0G8G2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ER membrane protein complex subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G162300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EMC6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8G2"/>
    <dbReference type="OrthoDB" id="16510at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072546">
        <property type="term" value="C:EMC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008504">
        <property type="entry name" value="Emc6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029008">
        <property type="entry name" value="EMC6-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20994:SF0">
        <property type="entry name" value="ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07019">
        <property type="entry name" value="EMC6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="15260" checksum="ABC4EFD5D1736698" modified="2022-10-12" version="1">MAPTPRTAIVQKSSSAKETAKKVDDADEVPAYSQENVQINMRIIYYSRTFLSIVGGVIAGVLGLTGISGFLCYFLIMMLASGGIAAKAKFDVHSYFDSWNRVLFDGIGQGMLVSFVILSCHLWYVSFCIISLLCRNVVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8K1</accession>
    <name>A0A8T0G8K1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G024400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8K1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055105">
        <property type="term" value="F:ubiquitin-protein transferase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019516">
        <property type="entry name" value="Glomulin/ALF4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013877">
        <property type="entry name" value="YAP-bd/ALF4/Glomulin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15430:SF1">
        <property type="entry name" value="GLOMULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08568">
        <property type="entry name" value="Kinetochor_Ybp2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="639" mass="69674" checksum="E38AE5B2AEF9CBA4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9S2</accession>
    <name>A0A8T0G9S2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G004900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9S2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19154" checksum="2306E90470AC0BEC" modified="2022-10-12" version="1">MVVHKEKMDLLKKTHGELELSIAKMRLEDLRAENFKKQYEVEQAVSKHYKKGASTSQARTGHGVHASPGEVEALMKKMEAEELGIQAWARSRTLIARIHLIEGDLHTLEKIMSTWVENPGVHIETLFEFLTSDLVEFENAFQLAGLDCRCSDAKCEFPFEISDAHREM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA00</accession>
    <name>A0A8T0GA00_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G063600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase GT106 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA00"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11299">
        <property type="entry name" value="O-FucT_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024709">
        <property type="entry name" value="FucosylTrfase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019378">
        <property type="entry name" value="GDP-Fuc_O-FucTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31288:SF22">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31288">
        <property type="entry name" value="O-FUCOSYLTRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10250">
        <property type="entry name" value="O-FucT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0294">Fucose metabolism</keyword>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="31"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="31"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00030350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0554112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="641" mass="72170" checksum="D6426818316B387B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAD6</accession>
    <name>A0A8T0GAD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Dolichol-phosphate mannosyltransferase subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G025200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the dolichol-phosphate mannose (DPM) synthase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Endoplasmic reticulum membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the DPM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAD6"/>
    <dbReference type="OrthoDB" id="2014333at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033185">
        <property type="term" value="C:dolichol-phosphate-mannose synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013174">
        <property type="entry name" value="DPM3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16433:SF0">
        <property type="entry name" value="DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08285">
        <property type="entry name" value="DPM3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0556091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10113" checksum="428F02EA7D7BDD9E" modified="2022-10-12" version="1">MKQVWKIGTIFTAVVGIWISLLLTPGLPPSLQLIVPYFPMYALASLGCYGLGALGYGMMVFRVCPEEADLLQKDITEAKTFFKEHGVDLSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBF3</accession>
    <name>A0A8T0GBF3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_12G159500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44229:SF4">
        <property type="entry name" value="15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0555309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="21648" checksum="413A6F2980CE86CF" modified="2022-10-12" version="1">MKAEIMGQAAFITGAAGGIGRALALALASRGVQVTVLDLKTAMGKETVRLVEEQHATISYKPTSPSAIFIHCDVTKPDELAAAFARHHEVFGRLDIFINNAGIGGGEPFYDGADWRKVIDVNLVAVIEGTSKAIQAMKDQGGLILNVASASSIVPTPYLPVYSASKAGVAMFTRSIAHIGMGIRVKTICAEVQRNWLMEPIKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBY6</accession>
    <name>A0A8T0GBY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle subunit SRP72</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G061100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SRP72 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:003738">
        <property type="entry name" value="Signal recognition particle subunit SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013699">
        <property type="entry name" value="Signal_recog_part_SRP72_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026270">
        <property type="entry name" value="SRP72"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031545">
        <property type="entry name" value="SRP72_TPR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14094:SF9">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08492">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17004">
        <property type="entry name" value="SRP_TPR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038922">
        <property type="entry name" value="SRP72"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="Signal recognition particle SRP72 subunit RNA-binding" evidence="10">
        <location>
            <begin position="579"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="574"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="577"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="596"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="620"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="667"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0556540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="702" mass="76313" checksum="74941F9C835E3549" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEK2</accession>
    <name>A0A8T0GEK2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G160000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEK2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035833677" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7085" checksum="8F94066AFBFE8A00" modified="2022-10-12" version="1">MLWICVVCIWFKNLLKLVQAGSALFAGTALIELDFMISSITGGLSSWPSSTRIHYLIESSHDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFD9</accession>
    <name>A0A8T0GFD9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Homoserine kinase</fullName>
            <ecNumber evidence="3">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_11G085400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-homoserine + ATP = O-phospho-L-homoserine + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13986"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFD9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="entry name" value="GHMP kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002288">
        <property type="entry name" value="PRK01212.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF1">
        <property type="entry name" value="HOMOSERINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861">
        <property type="entry name" value="HOMOSERINE/4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00958">
        <property type="entry name" value="HOMSERKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="GHMP Kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP kinase N-terminal" evidence="12">
        <location>
            <begin position="155"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP kinase C-terminal" evidence="13">
        <location>
            <begin position="293"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0556869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="397" mass="41157" checksum="9EC227096AAB6B8B" modified="2022-10-12" version="1">METLAGPKLPLQCHYSTRSKASLLHNGMLCDQPSLKVFPFSVRRECVKSQRLQVTCEKKATVLTPPLKQLTLSEPKVEYKYVKAFAPATVANLGPGFDFLGCAVDGLGDYVTAEVSEAVPAGEIRIEAITGDNGRLSCVPEDNCAGIAGKATLELLGAQSVGIILNLHKGLPLGSGLGSSAASAAAAAAAVNGLFGSPLSKAELVHAGLESEATVSGYHADNVAPSLMGGFVLVRSYSPLHLIPLTFPSGKDLYFVLVIPDFEAPTKEMRAVLPKEISMKTHIANCSQASALVTAVLQGDPSLLGAALSSDSIVEPQRAPLIPGMSAVIAASEKAGAYGCTISGAGPTAVAITDTLEKGKAVAAAMVKAFKEHGGLKAEAHVNRLDREGARIVEYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFE8</accession>
    <name>A0A8T0GFE8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G061700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11943" checksum="C78504B3BBFD21D8" modified="2022-10-12" version="1">MMRSSACYLAFQFQNGTSDSPSSTQIPPPYTSQDSAAEIQCRIPQKSIVTDEHKLTCSRFDSSREVRFVMIQAYTISVLLMAFVLFWTAGDACFVYGHSYRDSRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFQ3</accession>
    <name>A0A8T0GFQ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G105700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFQ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.160:FF:000002">
        <property type="entry name" value="Cysteine protease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000068">
        <property type="entry name" value="Cysteine protease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.160">
        <property type="entry name" value="Granulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000118">
        <property type="entry name" value="Granulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037277">
        <property type="entry name" value="Granulin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00396">
        <property type="entry name" value="Granulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00277">
        <property type="entry name" value="GRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57277">
        <property type="entry name" value="Granulin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035856767" evidence="7">
        <location>
            <begin position="28"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="10">
        <location>
            <begin position="46"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="9">
        <location>
            <begin position="132"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Granulins" evidence="8">
        <location>
            <begin position="372"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0557144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="50413" checksum="0F0589899ADFB8B7" modified="2022-10-12" version="1">MANSGENMALVATLALVLLVAVTHVESHVNLRLKTDPGLSEEERQFGDWALRHGRVYSGLEERQRRFRVWRENLDYVQRHQGKNSSYQLGLTRFADLTNEEFRRLYTGTRVDSGRVRRSSSSSGFRYKDVVAPESVDWREKGVVTKVKDQGSCGSCWAFSAVGSVEGINAIRTGEAISLSVQELVDCDQKYNQGCNGGLMDYAFDFIIENGGIDTEKDYPYTAYDGRCDVSKKNAKVVTIDGYEDVPENDEEALKKAVAGQPVSVAIEAGGRDFQLYTGGVFTGHCGTDLDHGVLAVGYGTEKDLDYWIVKNSWGEYWGENGYLRMQRNLKDSNAFGLCGINIEPSYAVKTSPNPPNPGPTPPSPSPPEVVCDKYRNCPAENTCCCTFPVGKMCLAWGCCSLKSATCCEDHYHCCPEEYPVCNLAAGLCLKGPQEKEGVSLMKRTLAHINWAAAWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGL0</accession>
    <name>A0A8T0GGL0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G008500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGL0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050568">
        <property type="entry name" value="Transcr_DNA_Rep_Reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252:SF93">
        <property type="entry name" value="DNA POLYMERASE II SUBUNIT B3-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10252">
        <property type="entry name" value="HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="4">
        <location>
            <begin position="58"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16755" checksum="E53FCC41D579CCD9" modified="2022-10-12" version="1">MSASNSESESQRSGEEDERTENGHSHEENGHSYEENENVNENGASTWRAGKAPLTPAFPISRVRRLVKSGGDVQWVGVEAGFLIAKAAEVFLEKMVEDAFDKMLEKRQHSILYPHLSSHVASSERLEFLSDFVPIKIPGETALANIKMANQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGY3</accession>
    <name>A0A8T0GGY3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G128600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18773">
        <property type="entry name" value="PDC1_HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051173">
        <property type="entry name" value="Ca_channel_alpha-2/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166:SF37">
        <property type="entry name" value="STOLID, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="199"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="630" mass="68483" checksum="DD2A405112D6D229" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQB0</accession>
    <name>A0A8T0GQB0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G183100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF298">
        <property type="entry name" value="MIXED LINEAGE KINASE DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="203"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="93"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0560479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="497" mass="56289" checksum="C7FEFC389E589472" modified="2022-10-12" version="1">MARVSDIDTEMIRANDGKQTNMMITSSGVEGTLETGANRCRNKHESGVSDEDLTTQDPWYSLLAFLNIGLYSSFFRFIGLCCSSASSSLDMAPHPPLTPDSPASPPSSSLWYHSSRIQRMIENQRMLEERGQFRTKVESEIEASKVTWTQIDATISQTEHSRKANREYFDLLKRRKYVRKGDQIVVKHEEQPDGHLFRDYDGLVVGQKLAEGGQAEIYEAVDQDGEDMVVKVFKAGTLLQDLETQWPAALMQVDDPKRMMPASIDGATLLQDPRMLDRFAFVMERQWGDLRTLIDQQMMRSHNRGPPFTPMQVVWLMLQIAEDMNMLHGQHPPILHKDLKAANVLVESPDPAPQQQQQQQQQQQQEGPVDDDGMYHVSVADYECSVGAEGTGLWRAPEILQQLKEEQYVSGSSGLMFSDKCDVYSFGMTCYELVTGRVPFEDCDFRQGCDLVLQGQRLQLPPDLDPCIHELILSCWALTPSHRPSFVHIIDVVTKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQJ8</accession>
    <name>A0A8T0GQJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G044900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00882">
        <property type="entry name" value="Ras_like_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="105"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="952" mass="108161" checksum="338596656BDA1E92" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR12</accession>
    <name>A0A8T0GR12_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">SOSEKI DIX-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G001700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SOSEKI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010369">
        <property type="entry name" value="SOK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048351">
        <property type="entry name" value="SOK_DIX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31083:SF6">
        <property type="entry name" value="PROTEIN SOSEKI 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31083">
        <property type="entry name" value="UPSTREAM OF FLC PROTEIN (DUF966)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06136">
        <property type="entry name" value="SOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SOSEKI DIX-like" evidence="9">
        <location>
            <begin position="12"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="233"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="300"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="409"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="522"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="664"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="268"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="310"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="676"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0560644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="764" mass="85861" checksum="5B17C250A8A92F6F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRZ1</accession>
    <name>A0A8T0GRZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G125500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="42477" checksum="368A2978AB06AB15" modified="2022-10-12" version="1">MKRNQRSPVLDSKTKRRPAKSAKLSSCGSSLRSAGSAAPPTFLDDLIEPVLAQLSISQIDALKQDSELWASMLQTPSLRRACAVVHPKVFGLVRWDSNRDTLLTSTFDLKSSEWVDIHLTDFPQGREYDDAMLAADGGLVCFVPRIGKKLAALPILVYNPLTNDRNSIRQGEGYKGELILVQLVMDEERKCYKVMLVYGDKYNGEASGAVVYDSRTGKWTKKNDGVVCGAGNTLLCDQPNFRVYDCSHRLLHDMDKRCARSRSFSSFKNHLYVLDDITTLPGKFVLSEYTLSRREIPIRDLKTLSGPSEEQGYIPVLLACKGFILLAWDNGDYYEHDQIFKLYDIAVNKEYNINADSGTTLQDLRSSLICDLRWDAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSF9</accession>
    <name>A0A8T0GSF9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G053100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015217">
        <property type="term" value="F:ADP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005347">
        <property type="term" value="F:ATP transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007031">
        <property type="term" value="P:peroxisome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045900">
        <property type="entry name" value="Peroxisomal_Ade_carrier"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46650">
        <property type="entry name" value="PEROXISOMAL ADENINE NUCLEOTIDE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46650:SF1">
        <property type="entry name" value="PEROXISOMAL ADENINE NUCLEOTIDE TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 9 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="5"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="104"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="9">
        <location>
            <begin position="208"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="355" mass="38361" checksum="68D748973DAA6A92" modified="2022-10-12" version="1">MGVDFKSLTEATSGAVGGLLSTTLLYPLDTCKSKYQAEAKAGVNRKYKSLFDVFWESVGQGKVSSLYQGLGTKNLQSVISQFIYFYSYSIFKQWYLAKAKVSKMGTGTNLLVAAAAGTCTAVLTQPLDTASTRMQTSAFGKSKGLWATLTEGSWQEAYAGFGASLVLVSNPAIQYTVFEQLKDFLLRPEVVVEVVGTERVRKTSPKVLTAFQAFLVGALAKTVATILTYPAIRAKIMLQAAESDEDKARRLNGGNDPNVRHRARNMLEAFQQIGTEEGVRGYFKGLHAQIVKTVLSAALMLMIKEKVASSTWLVMMALQKYLAASETKMKTVSLPASAVAPIGVVGIALASKAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTK4</accession>
    <name>A0A8T0GTK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G068800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121:SF21">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24121">
        <property type="entry name" value="NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="860"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="899"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="949"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="3">
        <location>
            <begin position="857"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="30"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="985" mass="113553" checksum="2746277995241D78" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU75</accession>
    <name>A0A8T0GU75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">homogentisate 1,2-dioxygenase</fullName>
            <ecNumber evidence="4">1.13.11.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G184900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.5" evidence="4"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU75"/>
    <dbReference type="OrthoDB" id="1689029at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07000">
        <property type="entry name" value="cupin_HGO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000034">
        <property type="entry name" value="Homogentisate 1,2-dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046451">
        <property type="entry name" value="HgmA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046452">
        <property type="entry name" value="HgmA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01015">
        <property type="entry name" value="hmgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056:SF0">
        <property type="entry name" value="HOMOGENTISATE 1,2-DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20510">
        <property type="entry name" value="HgmA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="9 12" id="KW-0408">Iron</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase N-terminal" evidence="14">
        <location>
            <begin position="32"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Homogentisate 1,2-dioxygenase C-terminal" evidence="13">
        <location>
            <begin position="309"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="370"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>homogentisate</name>
            <dbReference type="ChEBI" id="CHEBI:16169"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR605708-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF20510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0560502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="473" mass="52576" checksum="40415F1577A636F8" modified="2022-10-12" version="1">MAVEKVNSLMEGLKVNGDTDNASHDTGFEDLEYQRGFGNHFSTEVLKGALPVGQNSPLKCPYGLYAEQISGTAFTVPRMHNQRSWLYRIKPSVTHEPFHPREPTHERLVSDFSSTSAASVTPTQLRWKPSPVPEAETNFIDGLSTVCGSGSPFLRHGYAVHMYTANISMEGCAFANADGDLLIVPQLGRLWIKTEMGKLEVKPGELVVLQLGIRFAIELPDGPSRGYVVEVFSGHFQLPDLGPIGANGLADPRDFLTPKAWFEEKSFGTGGFTVIHKFGGALFDAKQDFSPFNVVAWHGNYAPYKYNLKKFCPFNTVLFDHADPSINTVLTVPSEKPGVAVVDFVVFPPRWSVAEHTFRPPYFHRNCMSEFMGLIYGMYEGKADGFVPGGASLHNCMTPHGVDTATYERTICEDPKPSKIPDHALAFMFESSLIPRVTPWALNSPQRDPDYYKCWIGLRSHFDRTNEPEAEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWT3</accession>
    <name>A0A8T0GWT3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G189300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0563007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37713">
        <property type="entry name" value="OS05G0176600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37713:SF1">
        <property type="entry name" value="OS05G0176600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8170" checksum="4034728136C7A6DB" modified="2022-10-12" version="1">MSNELEVRRREPKKPPFKFLVPLLYAPVLPLIRIGLRRQPVLRDRLFGVVLAAGLLHGGYLVTDLYDQESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY09</accession>
    <name>A0A8T0GY09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G007000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="103" mass="11130" checksum="C85607987943E4DF" modified="2022-10-12" version="1">MLSNGSCVSFNPDDDFGTSCSVLKIDRRSAEQAVLVRNATVQERNALIDGISGHFQQPPKSVEPVISACPRSQRVQKAHPVPKIETVRVRYGDTLADIASGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY17</accession>
    <name>A0A8T0GY17_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="8">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G092200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
            <location evidence="8">Extracellular space</location>
            <location evidence="8">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="8">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="8"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02176">
        <property type="entry name" value="GH16_XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.200:FF:000025">
        <property type="entry name" value="Xyloglucan endotransglucosylase/hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008263">
        <property type="entry name" value="GH16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01034">
        <property type="entry name" value="GH16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0052">Apoplast</keyword>
    <keyword evidence="8" id="KW-0134">Cell wall</keyword>
    <keyword evidence="8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0964">Secreted</keyword>
    <keyword evidence="1 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GH16" evidence="9">
        <location>
            <begin position="26"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="32969" checksum="20EEAC151E28B846" modified="2022-10-12" version="1">MGFKGSPNGVVAISFFTVVCLVMAGVSYGATFTEQFDAFSSDGYHVQVAPDGQEAKIVLDQVAASGFGSKNQYLFGNISMKIKLVPGDSAGTVTAYYLSSAQPAHDELDFEFLGNASGQPYVLQTNVFANGVGGREQRINLWFDPSADFHSYGVLWNKNQIIFTVDDKPIRLYKNSEDLGVAYPKSKPMGLYASLWNGDQWATEGGLIKLNWTHAPFIVSFKEFSTLDGCVVTNNDITPCTATTTHWWEASAFQTINRNQAEQILWVKENYEVYDYCKDTKRYTTEPVECSRNVPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZY8</accession>
    <name>A0A8T0GZY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CDT1 Geminin-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G084300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Cdt1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070182">
        <property type="term" value="F:DNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000076">
        <property type="term" value="P:DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071163">
        <property type="term" value="P:DNA replication preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030174">
        <property type="term" value="P:regulation of DNA-templated DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08767">
        <property type="entry name" value="Cdt1_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08674">
        <property type="entry name" value="Cdt1_m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1420">
        <property type="entry name" value="DNA replication factor Cdt1, C-terminal WH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045173">
        <property type="entry name" value="Cdt1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032054">
        <property type="entry name" value="Cdt1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038090">
        <property type="entry name" value="Cdt1_C_WH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014939">
        <property type="entry name" value="CDT1_Gemini-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28637:SF1">
        <property type="entry name" value="DNA REPLICATION FACTOR CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08839">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16679">
        <property type="entry name" value="CDT1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01075">
        <property type="entry name" value="CDT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDT1 Geminin-binding" evidence="4">
        <location>
            <begin position="71"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="401"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="497"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="620"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="403"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="535"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="556"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="819" mass="90049" checksum="23EC90A30E1E9E99" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H151</accession>
    <name>A0A8T0H151_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G085500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H151"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="44460" checksum="CE49E833414EDB88" modified="2022-10-12" version="1">MQSTRLHHRLSERRSGAENLYSEAIDINEADTVFTLPPKHSELILEDNSGLPGVRVGTGYIADDGQLVPQPMDFSKKNYMSTMDLQDLLIKLVRPDIKVETTGLELDAAMRLLLMEAMAQYPSQSANPKYDGTDYPDDYCKFFLPGLSRVRPKGALRIYNKIGRAYGFTIDNSYVFDIETGRSFFLTAVIYTNANGVLNDDKYEYEYADRILADLAEVLGRALWQIPDSSAALSSPLDCTPSSLWPIRTKPPTISTFSESRTATQENEDSKLPAEDKSYPVEKMLSELVVISRAEDHSLSRNQSPVQRMTSNIVVPEEGSMGSSKEKPNNSGCSSILQHGADKRVQTDTINLPTTAEQQSYTFVLLPITQVSPSEVVSSPPCADTFKSIKPCYKYFLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1T7</accession>
    <name>A0A8T0H1T7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G165600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1T7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="5341" checksum="00B4794B70B76BF7" modified="2022-10-12" version="1">MVVIGGGAQGEAALAATEDSGFFVCRANNSSHEAPVAATPAAPAPSPAPATPAAPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2M1</accession>
    <name>A0A8T0H2M1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G157400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2M1"/>
    <dbReference type="OrthoDB" id="643149at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009627">
        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00010">
        <property type="entry name" value="AAI_LTSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039265">
        <property type="entry name" value="DIR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122:SF13">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_LIPID-TRANSFER PROTEIN_SEED STORAGE 2S ALBUMIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122">
        <property type="entry name" value="LIPID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00234">
        <property type="entry name" value="Tryp_alpha_amyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035915472" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0565027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="11871" checksum="C727E7DA6B2C2982" modified="2022-10-12" version="1">MKLQATPAAAMCMVMLLVASEMLVTSQAAGCDIFQLVPCMSASKNAKVVPSKQCCTNIANMGKGLPGAKCLCSLLSHPLAKSNGVVPRIALGIPQKCRIAVPKGFVCQGIRVPGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3E3</accession>
    <name>A0A8T0H3E3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G178200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3E3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33133:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33133">
        <property type="entry name" value="OS08G0107100 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="336" mass="37253" checksum="FC194DCBBC42F6AD" modified="2022-10-12" version="1">MVEGYPYGLGGWGVPGIFKEGGRLMVKHWKLLAPFVFAFVLPTALVQLAEVLGISWYSGQSPFLPPGPHPHNHALHVYSKVSAGMDADAPLPPTPSGTALLVMLAVGILMWLLASLAVASIAKTVQYIYAEQDEDPAVIKSTFQSLPHALWRLLLTSIWIFLLTVATIFTVSLPFYIIAWLFNHKHAQLFNTLQQIFLSVSLTILGFLFLLSQEVAVLEPHNYGLEALKRSAKLVQEKFLASLIVFLVSIGVGALLSRLSTVAGAYPSKLPHWTIYIFAVLLAILYLVYMVYMLLVTIVLYFSSKLQYDAEDESLPEFRYRSGDNPYTPLVVPAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H679</accession>
    <name>A0A8T0H679_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G090300</name>
        <name evidence="2" type="ORF">KC19_7G090600</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H679"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="19315" checksum="A05A66A467AF967C" modified="2022-10-12" version="1" fragment="single">MRNTLPTQPPLPNCIAEQLPVDGPQISHPWASSKDVCQEMGTDGISPSPHTISQQSPFELHYGSKRSYVWTVIWKEGPLHCLIYHCRQWFPEYTLLPRHSPISQSQDVNLFQKPKSFPFRRQDPGTCKTQRILHSAYYCLEISNQLSSAISRLGCHGPFKHIEYVSSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6G4</accession>
    <name>A0A8T0H6G4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G058400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast stroma</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RuBisCO activase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009579">
        <property type="term" value="C:thylakoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044960">
        <property type="entry name" value="RCA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32429:SF32">
        <property type="entry name" value="RIBULOSE BISPHOSPHATE CARBOXYLASE_OXYGENASE ACTIVASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="19909" checksum="639A9877CA31D497" modified="2022-10-12" version="1">MASSCAVMQTVSTAQVNASLGAQATSKSTLPSSALFGCKSKASANVALGVAKCKGRVVAEAEGAPKKVDKWAGLGKDISDDQQDIQRGKGMVDALFQGAQGMGTQTVMMSSYDYISTGQRTYNFDNTSDGLYIAPAFMDKLVIHVAKNFMNLPGIKIPLILGIWGGKGQGKSFQSELVMKKLGIKWVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H770</accession>
    <name>A0A8T0H770_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Adenine/guanine permease AZG1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_8G150000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H770"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005345">
        <property type="term" value="F:purine nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015853">
        <property type="term" value="P:adenine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015854">
        <property type="term" value="P:guanine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045018">
        <property type="entry name" value="Azg-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337">
        <property type="entry name" value="XANTHINE/URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43337:SF1">
        <property type="entry name" value="XANTHINE_URACIL PERMEASE C887.17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="292"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="478"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="508"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="557"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0564922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="583" mass="62149" checksum="CAFFC706883EDE32" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H945</accession>
    <name>A0A8T0H945_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G173600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H945"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035895761" evidence="2">
        <location>
            <begin position="29"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="277" mass="28767" checksum="9570C870645102C8" modified="2022-10-12" version="1">MCRPSWVGVAFAAVVLVVTASCVGTASARLLEGDIRAAVLGKDEEDSTMTVAVPDEVDHVLNVEGADLNTKFQGRMLAGGGGGGGGGNRGGGGGGGEEEGVVEEEVVVATSREEGVEAVEVVVEEEAVEVVVEVEEVVAVTGEEGTTTGEEGEAHTVPRTSHQGEAVAEILPEGVEEVVAEEEVVAEEEEEVVVVVVVEAAAAEEVVAEGSALVIAQEEVPEEAVAAVAVETNHRLPRPPQFRPLQRHSHLLRTQSDDHVKIPASKLWTPVKGEAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9Y6</accession>
    <name>A0A8T0H9Y6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNI-like superfamily protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G115900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9Y6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318">
        <property type="entry name" value="PARTNER OF PAIRED, ISOFORM B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13318:SF119">
        <property type="entry name" value="RNI-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="410" mass="44685" checksum="8C1FC46B80D6A20F" modified="2022-10-12" version="1">MDGGGRCQQSELGRLGTDRVCTCAFCTEGRIESKFGECSRCAAASSREPATSAAVPLRGDVKANSVPVLANSVSGQGDRSSVGLVSSRSLQTGEALKASSRHCRSLVSLCVGYLGEHLEDLIEDIDDIAPAFPFHVKGKLLAIARRRGLLCDELLASLADNSWEILDVSGSDVTDASLIVAAQTCPRLQDVDISRCNKLTPTAVRALVEHCPSLRTLRCGGTPMSDTVARKSISHILPKLNRNEEEDSWEALETKPVAEGAQALRWLVWPGIDANSRERLANECPRIVINPIFSWKTYGVVPRAAQPRVVLDEFLLDDIDPKTWAVVTKVAVRLPKAAVSTTDELKNELSVAEKFRLAFVARDERLAPKRAKNARQNQRRAEKAWLSSDTEAKSHVWAGIARKSLKNLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAM4</accession>
    <name>A0A8T0HAM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GTP diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G021700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RelA/SpoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.5" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="427950at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008728">
        <property type="term" value="F:GTP diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.460.10:FF:000025">
        <property type="entry name" value="probable GTP diphosphokinase CRSH, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.10">
        <property type="entry name" value="Hypothetical protein af1432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262:SF12">
        <property type="entry name" value="GTP DIPHOSPHOKINASE CRSH, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21262">
        <property type="entry name" value="GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13328">
        <property type="entry name" value="HD_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="HD" evidence="8">
        <location>
            <begin position="339"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="699"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="736"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="117"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="862"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1314"/>
            <end position="1335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="866"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0568473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1335" mass="147172" checksum="80E41D1417521A40" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCE1</accession>
    <name>A0A8T0HCE1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G094600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:001016">
        <property type="entry name" value="Leucine Rich Repeat, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF7">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="263"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="286"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="419" mass="45880" checksum="462793C5FD47B1AB" modified="2022-10-12" version="1">MVRLTAALISALNDGCDLATIETLTVPGRYFHEISGIDACEKLSRLDISKNSITSLESISMCTNLKWLSVAENKLTSLKGIETLTKLTVLNASRNAITSVSEISTLVELRALILNDNQITKVTRFDNLVKLNTLVLSHNPIRELGKSLNKQLELTKLSVSHCKIQILGASLKRCVALEELRLAHNQLSELPKEIERNGRLRILDLGSNNLQNWQSLQVLKALHSLSNLNLRGSPICSVADYEQEVKSLVPTLQILDGHPLVPGKVKRKYEGKKPSSKMTDESVGGPKRDTNGDQTKRTKVNSIADGAKEKGSRPPKDSQDEDAPDKPFVELIKAQPTEVKRLSDIRQDSGVVAVIDGKKDVGGVWKRKRGIEALTLLKEPEIGTGGPSSWDTPGAAITNDVAAAKLPPTSYSRWALKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE40</accession>
    <name>A0A8T0HE40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type E3 ubiquitin transferase BRCA1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G040100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd22671">
        <property type="entry name" value="FHA_APTX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47776">
        <property type="entry name" value="F5A8.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47776:SF2">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN TRANSFERASE BRCA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BRCT" evidence="10">
        <location>
            <begin position="437"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="793"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="401"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="600"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="756"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="401"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="611"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="657"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="759"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0568708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1025" mass="112381" checksum="C4F1EF6DE2424D7B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE59</accession>
    <name>A0A8T0HE59_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G075900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7726" checksum="25A42CC24A8B96A9" modified="2022-10-12" version="1">MVSGTDSDLDKLRINATSLGQYLPGIRQKECIQVQYSSSHKYSTHKCLGVLFSQIRLRKPCLPCKSIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFR8</accession>
    <name>A0A8T0HFR8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">VPS37 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G067200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VPS37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000813">
        <property type="term" value="C:ESCRT I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006612">
        <property type="term" value="P:protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043162">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037202">
        <property type="entry name" value="ESCRT_assembly_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009851">
        <property type="entry name" value="Mod_r"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13678:SF2">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07200">
        <property type="entry name" value="Mod_r"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140111">
        <property type="entry name" value="Endosomal sorting complex assembly domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51314">
        <property type="entry name" value="VPS37_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0967">Endosome</keyword>
    <keyword evidence="5 6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="VPS37 C-terminal" evidence="9">
        <location>
            <begin position="189"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="185"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="29799" checksum="C862C7DE3F1978B7" modified="2022-10-12" version="1">MLFSRGGQQQQQQQGQPPPPSQSWYPPSVAGAANSGPSRVPPPPPPNFGAHPSGINPLARHPVTDSRPTSGVYPPSTLAGSYSSGGYPPPTSLPPSSSGSYSSNAGPANSVAGIKDKSPEELTRLLNDKDAYSAFLHSLDEVRRLDKISEELRKSTIDESKNNLEKESEIAELRTQCMIIRNTELAASREKFEEVDKRYREVQANCSPHALLNKLQDAANEADEESENLHRSFLAGEIELLEFIQKYRKQRLHYHRRSLIRMAALSAMTPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG79</accession>
    <name>A0A8T0HG79_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Rubredoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G153200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00730">
        <property type="entry name" value="rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024934">
        <property type="entry name" value="Rubredoxin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024935">
        <property type="entry name" value="Rubredoxin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48136:SF1">
        <property type="entry name" value="RUBREDOXIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00301">
        <property type="entry name" value="Rubredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57802">
        <property type="entry name" value="Rubredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50903">
        <property type="entry name" value="RUBREDOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rubredoxin-like" evidence="6">
        <location>
            <begin position="104"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="18182" checksum="9CC3C3FD78F10DAC" modified="2022-10-12" version="1">MASSVMSLCGSSVVTVAAVQRVAGTSGFEQAPTSVRFGNGAVAFKRASLVVRAEGKVEPGPGGRGNAPTTPTSPPGLSGTEIPLSVITSSAPLAQGTDKPVGERIAYVCQDCGYVYDQETPFEDVPDEYNCPQCSAPKMRFTMANASVEEMLDTTKEDDAVSRGSGEKSGSPPSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG89</accession>
    <name>A0A8T0HG89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G153900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035516">
        <property type="term" value="F:broad specificity oxidative DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051747">
        <property type="term" value="F:cytosine C-5 DNA demethylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA alkylation repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="entry name" value="Alpha-ketoglutarate-dependent dioxygenase AlkB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032852">
        <property type="entry name" value="ALKBH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573">
        <property type="entry name" value="ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31573:SF1">
        <property type="entry name" value="DNA OXIDATIVE DEMETHYLASE ALKBH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="3">
        <location>
            <begin position="217"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="316"/>
        </location>
        <ligand>
            <name>2-oxoglutarate</name>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR632852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0570320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="352" mass="38664" checksum="3E46EECDCA7871F1" modified="2022-10-12" version="1">MMAAARSPNQIMAMYARKKQKLSSPEPAAAESNPAPVPLPAEAKEILGQAAETTRPVRTYSTHPTYPFPIADLPITSAALQAGLAPTSAGKVIKKGDLDLLYFQPFIKSPTANLLYKHLLEELPWYKVMYLARGMTINTPRFTTVFGLDETAFFEPPPNEHEDEAKAGTHIPVAGSRVMSAISKQPVPGNVYQKPPRPIPRCLQELKGFVEQATNETYNFILVNFYADGTHSISPHSDDESFLGHNPCVASLSLGGTRDFVMKHKTKKDLGSEKFALRSGDMVVMRGTTQANWLHSIPKRTGKTQTTMARINVTFRKCINAKGSNNYSHYNVGSGPVHRFVNGSMVQSSTTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIT8</accession>
    <name>A0A8T0HIT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G122500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIT8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="28373" checksum="775EE12D32A88FA0" modified="2022-10-12" version="1">MSQDKVQSPYMPGLKEPVDLMDEQEGDKSGGGAGRFISLGNPGDVGGAGREKQQGDYYTPVATEVVKKGGDEGKPSKGLDGSREGAEMNDLYSPEAGVDIVTSDKQSPPQKKTKEMAGAGTDEHEQRGEESGTVVSGPGLVEAGKGMATEVSDSLVSVRGRMMEKLSGLQLPSESLEAVRRTFETGLKGAYTTTRDAVQRTKQSLLDLFPSSHTSSSATEARKVVEEMEKDMLGNSEGSGEDMSQISEGPKVSISETTSAPQFMRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJJ8</accession>
    <name>A0A8T0HJJ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G201500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036435073" evidence="1">
        <location>
            <begin position="27"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="153" mass="17208" checksum="71280F32222D09C1" modified="2022-10-12" version="1">MEMSLVMRSFVLVTLAFCLVTVAASAYELPLMPALDPVVESQSSQAPGSMSQLIGVYFGDQVRWRPFLQRHEQRAYHTRHRFVRAYRPRPNLQSTDTIGKDVDLEMGSNPGHDLEGQQFYLRGNLPASPLVSNPETVVEVATRQHIPVELVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJZ1</accession>
    <name>A0A8T0HJZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G212400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJZ1"/>
    <dbReference type="OrthoDB" id="1936518at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052116">
        <property type="entry name" value="Centro_Cilium_Assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23170">
        <property type="entry name" value="NY-REN-58 ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="97"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="98"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="173"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="386"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0571116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="402" mass="42602" checksum="0FB4F1A77D076249" modified="2022-10-12" version="1">MASENSEDGSAALSDASSYKCDTLSPESRVASPKVQINPDSIGKPSPRKSPRTSAAFGSYLNKAIAQGSRAFYGTDSEASDDEACCDKELIGKAAHALSEDINDRIRHRVESCSPTSSKREPVAGESATGKEVHDPVSTDEAPSSAAKVDQGCNSSQPDCEDRSSQTASPGEEAGKIESNKRPDVAHTATQSSDAAPPAEITPPKPDDAHRPSANPELLKQRAIQLEERVRLLKERKSSSRMPSSIPGGSFVEQLKKIDLSLDGGTLKVCDRNLSENALATIVNAVKNNDKLTELDLSGCCIQKGDDLADLVRNAPSLQRLLLAWNCLGSARTGVAALAAAVASATSLQEVDLRSNRIGPATAAALALALRTNNTLKRLGSSRVGKEKRKNRTSKHFVLSHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJZ6</accession>
    <name>A0A8T0HJZ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G211900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJZ6"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF99">
        <property type="entry name" value="GLYOXAL OR GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035724910" description="Galactose oxidase" evidence="2">
        <location>
            <begin position="27"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="42"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="432"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="528" mass="55604" checksum="B7AAF64818630B3A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK87</accession>
    <name>A0A8T0HK87_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G219800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK87"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035929342" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="98" mass="11051" checksum="D3813055EB3A8108" modified="2022-10-12" version="1">MPLVLLLHKCCCPLVMQSVWLRVWPLAKADRSPTTCVVSATPYELKNLQLSIKSWTLGFGRRVGVRNFPQETNATFGRISTEIYSLFQTPSVHKGCKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKA5</accession>
    <name>A0A8T0HKA5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G221500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="123"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="17601" checksum="59A857C3334BE1AA" modified="2022-10-12" version="1">MERQQGVQPAGSTTDVTNIHGRMDEICAWAALPRWAVDELRPLARQLARALSPKEAPLLGSTGGAQPGRRVLVYHVREPRGSASGGECNAGSGNWRAAGVTARIDIHVQGGFSDGWIDRRKEGRKEVRKEGMDRLGQSRGAGEDDPSTSAALIRSALHCTAHLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKB9</accession>
    <name>A0A8T0HKB9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G223100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34863">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34863:SF1">
        <property type="entry name" value="OTU DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="480" mass="56186" checksum="DB8C6AE7CF725238" modified="2022-10-12" version="1">MDSQPLNADVDAACFMMDIRDLPQMFGELIRPAIHLSFLRDLNHFKQWIIIISDPVIVKLYGGDTIEERQHYKRLICRELRRKHGLTLTIAEHDLILSKSRVNIPLQALVESLWTCGHRECRVGFYGMKWAYEKAKPKIDRCIQLHGSLRAGSVRGSRQNMFDIGVKLHATEVNIFGYGESQRWPGRIFRKGRVHEMFNIPDFGSIDFGIRDHPVIGTIKIYQELTHEVLSHIPKASLDDYPATVRTMRIRWYQLDSLLRAWEGYGEDELRENLLGTRIEVSIKNVHTVTEAYNYCIIYDLLTIRGLEKMLGGPFHVRTIPVNEILTDFSNKLNRFARKVRGRDETRTTDQMLAALTEARQSIGWSGKNMDAQLKKARWWRGRHDRNRGAGEDRQFHYDGWEADEPRLRPMIQDFLDSVEWYNHSASRTYDPHPIYLKKARGSGFLQQRGRYTDRVGAARWYVGRYQERWRNEVRTRPGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKP2</accession>
    <name>A0A8T0HKP2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG005400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11330" checksum="2AF085C56540CC22" modified="2022-10-12" version="1">MLQDIAKGGLDVLQRRCIGVQDSPSRDAVPASGDITLKPLLSVEILCLSFHHPHRPSVGVTLHGVESSFADFIGDNLKENPTLERRILLIGVSTSGGAEASLTEGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKR8</accession>
    <name>A0A8T0HKR8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG007600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7808" checksum="45743424F3B40684" modified="2022-10-12" version="1">MQSDSERRCCPGQVPLPDSVCSHGPKVYTTFCRFVVSSQSHRLVRREKTLTPRQHEPHASASLYGGSHLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKY5</accession>
    <name>A0A8T0HKY5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG012600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9348" checksum="8EECEE4ED871FCDF" modified="2022-10-12" version="1">MECTNSVLARECQSYRRGRVGLVPFVEGNFCLCNRCPRISRPVESRRYGGKTCTPLYAQGVCGAFGTEIYGFQHAVAVSPPCPPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL71</accession>
    <name>A0A8T0HL71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG012900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12119" checksum="112D5272DAF96A3F" modified="2022-10-12" version="1">MTRDQCQFRQTKGDIKLPKKNLPHSLTSGQNSGQCSNVVEAEKESTWADYGKMIGTLQGKHTPEEEKSNRLLLLSPLDSDILLADILDTYLSIEFALPQLIPCQRLDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLG9</accession>
    <name>A0A8T0HLG9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG024300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12151" checksum="9551284B63469A14" modified="2022-10-12" version="1">MESWSPQTKLKYGLCTLDDTGRIASIWNFPDFNELLREIDEGEESTVQSSARSSEVNGDAADSDVVSDSVEGELDAIVTFRVTNVSIRHSLPLTEDAAKTIESDGNAKLVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM10</accession>
    <name>A0A8T0HM10_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG040400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035814688" evidence="1">
        <location>
            <begin position="27"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="21068" checksum="5FA703681BD1B061" modified="2022-10-12" version="1">MINTSTFLGPFFLHLLLSNSFFGRVAVPLPSHATTITYQTKQVHVNVTNWHSKLITFKCEFICNKGINTLTHANPLKNQSALFRSAFTSTKSGEGSNKALGSTHREQQNESVLNCHHLVLLSCGPPIRLSKHCRVVQLRNTRLEILIHLVEINSSLFLEQILGVHGFHTINVHHHLDFADCSQRLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMS6</accession>
    <name>A0A8T0HMS6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG070700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14891" checksum="29C9B48335A4BDB5" modified="2022-10-12" version="1">MHSSSSCQSMGDRQRLPSEWFSSGFYSFGTRVATGVVAADLVRRRRPLCEKMRDFGRNLQVEVGVDVSNAVAVNGERGRRDFVELWRSYSQISEICTHPNNPFSCKQQHFSFYYGYWVLCNLWLYVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQE4</accession>
    <name>A0A8T0HQE4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="14">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">KC19_VG151700</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 14">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="14"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQE4"/>
    <dbReference type="OrthoDB" id="10248617at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.270.10:FF:000011">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.150:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1070.20:FF:000001">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1110.10:FF:000005">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1800.10:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerase subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1070.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF007175">
        <property type="entry name" value="PRK09606.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 14" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 14" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="19">
        <location>
            <begin position="32"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="18">
        <location>
            <begin position="202"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="20">
        <location>
            <begin position="465"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="21">
        <location>
            <begin position="564"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="22">
        <location>
            <begin position="649"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="16">
        <location>
            <begin position="708"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="1079"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="828"/>
            <end position="892"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0573134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1185" mass="134351" checksum="3B8122A625CEBC59" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQJ2</accession>
    <name>A0A8T0HQJ2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG161100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035903095" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="59" mass="6558" checksum="C953174C4798E4E5" modified="2022-10-12" version="1">MISMVTFHFCLIFISIGRLSSVLVHSVGWSPTKVRSRAVLFASQGGRGREGRGYYPKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HST2</accession>
    <name>A0A8T0HST2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG230100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HST2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9851" checksum="2DC3F70602DCA386" modified="2022-10-12" version="1">MAGSREDAHQHGDEDGSRSEWEDENTLVPNTVFLYSPLIPRLSRMFKNPLLAESCLIRGTNLIMRVQTSMRFEIGLNQSNGGVHQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSV4</accession>
    <name>A0A8T0HSV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG193200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase zinc-binding" evidence="1">
        <location>
            <begin position="289"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="60707" checksum="B8D58B794E41ECE5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSW2</accession>
    <name>A0A8T0HSW2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG194100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSW2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="14443" checksum="0691A1A92F48D4CC" modified="2022-10-12" version="1">MLILPLRVTGSKEVGFDVEGGCGRRRYVMSGALAREGGSDAREGSGEPTVSGVEASGGGRWGGWGDSEASWGCEKGSGVQSTRVGSGLVGIGSLWTCASNLGVDNSLLVFCENGLVLSTNVLHPKTLRWLTEGLSPVSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSW4</accession>
    <name>A0A8T0HSW4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG211600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9932" checksum="68EB31D67BF39D83" modified="2022-10-12" version="1">MYATYWMERTAASAVCGHWIRLVVESNLCSLLTLIPPLWMVSLKRSLNLEIVQIRNLEKSVELAGRYFKMTFFSELLSKCLYLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTQ8</accession>
    <name>A0A8T0HTQ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG220000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035828102" description="Secreted protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="7393" checksum="C42592AE5197F625" modified="2022-10-12" version="1">MAFCLVLLVFWYISGSALIVSTHKWCSLQLHQGSSWCHDYFNLGKLLCREHRIFFEKMYYGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUL6</accession>
    <name>A0A8T0HUL6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG245200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7681" checksum="5E995A18CFEC0748" modified="2022-10-12" version="1">MYPGVALTAHWGVAAGCNASQEIGNNTQESLVILFTGRAPRGSQMYCQVWIWWVWQMSPKQLGGFSILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUN6</accession>
    <name>A0A8T0HUN6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG271200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUN6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37705" checksum="D3C926F2D008B5B6" modified="2022-10-12" version="1">MGNCNHKFHITCIAKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTANDAGMDDFSWMTHDYEVEMRASEIPDAKDREFFCRNFGGHWSIHRNRFFRFPKPEVVVDADGKRREVERDYGQLDEYKMYDRTPVGRALVLAKLEEAILHRRTFTEESFKYSDLDYWVITEKFDDALQKIVNDWRRALRAEDNSSRWSRNRIEKIVQETVAKIDKAKELWNGKNSKKRNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUY8</accession>
    <name>A0A8T0HUY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG299900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051419">
        <property type="entry name" value="Lys/N-term_MeTrsfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176:SF79">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12176">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0574882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="16423" checksum="B923AC8A6BC2A510" modified="2022-10-12" version="1">MAPKKKGGAKKGKGEKKPAKVLMYHDEEYWNNRYTKHPEPFDWYQSYKELKALLTIYISKDQVNMNVGCGNGLLGEEMVLDGYVNVISIDNSAVCFEQLNARYKGKKEYTGLTWFRQDMKELKMLKDLTIDNVIDKGKLPFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVW5</accession>
    <name>A0A8T0HVW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Gfo/Idh/MocA-like oxidoreductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG274300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840:SF5">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42840">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12117" checksum="864E0191E15F0914" modified="2022-10-12" version="1">MRKMFWRVVGSLGTVEAERTVQNGQHGYKTTYQPAKGETQEVFGPFAGVYEELRVFAKDVAKCVFQGLSGEEADKRSSVLEAMRDVAVIEAMINSSDNKGTPKVVEIALT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZK6</accession>
    <name>A0A8T0HZK6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G052600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ZIP transporter (TC 2.A.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZK6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004698">
        <property type="entry name" value="Zn/Fe_permease_fun/pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00820">
        <property type="entry name" value="zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF44">
        <property type="entry name" value="PROTEIN ZNTC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0576065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="40263" checksum="BF48EED90901BD47" modified="2022-10-12" version="1">MSSQPSYIVRMFGRSSELPVSSSNFLHNLLKLPSEELVSGTVEMSSADCSPAGADSCYDKDAANRLKAAAIAVIFFASALGVLIPLIGRRSHFLRTDGNPFFIAKAFAAGVILATAFVHMLPTAHDTLANPCLPEDPWGKFAWAGFIAMLAALATLVMDFAATEFYMHRHGHSHGEDKISDSAVKSDDVESNNHHGQVMAHPHIHEHVTDDSAFSNVRHIVVAQVFEFGIVAHSIIIGITVGVSSSPCTIRPLFAALTFHQFFEGFALGGCIAQAGFRNMTALVMGFFFAITTPLGIAIGMGISTTYNENSPKALIVQGVFDSISAGILVYMALVDLIAADFLSKRMRSSRQLQLFAFLALFLGSGCMSVLGIWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I014</accession>
    <name>A0A8T0I014_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">2-phytyl-1,4-beta-naphthoquinone methyltransferase, chloroplastic</fullName>
            <ecNumber evidence="4">2.1.1.329</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Demethylphylloquinone methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Menaquinone biosynthesis methyltransferase ubiE-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">MENG</name>
        <name evidence="5" type="ORF">KC19_5G047800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the biosynthesis of phylloquinone (vitamin K1). Methyltransferase required for the conversion of 2-phytyl-1,4-beta-naphthoquinol to phylloquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>demethylphylloquinol + S-adenosyl-L-methionine = phylloquinol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:40551"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28433"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:87844"/>
            <dbReference type="EC" id="2.1.1.329"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Plastid</location>
            <location evidence="4">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.329" evidence="4"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I014"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052624">
        <property type="term" value="F:2-phytyl-1,4-naphthoquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042372">
        <property type="term" value="P:phylloquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01982">
        <property type="entry name" value="MenG_phylloquinone_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032904">
        <property type="entry name" value="MenG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001244">
        <property type="entry name" value="PRK00216.1-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="34149" checksum="00912FDF135A3B96" modified="2022-10-12" version="1">MAAMMQGCGVQAIGILCSSPAVCSTSSSSSCVQLPRSSFLGGRWAHVKEMGISSCRSKVAHAGVAVRASVVEEGKVRPLVTTEQVGEAEVGQRQELFNKIAPMYDSLNDWLSLGQHRVWKRMAVAWSGAKRGDRVLDICCGSGDVSFLLAGKVKPTGSVVGLDYAQEQLDVAARRESESSFAGGRRIDWRLGDALALPFEDGSFDAVTMAYGLRNVASVPLALKEIHAVLKPGAKASILDFNRSENEDVVGFQGWMLDNLVVPVASQFGMQEEYAYLKTSIARFPTGPQQEELAISAGFSTAVHYELAGGLMGVLVLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I607</accession>
    <name>A0A8T0I607_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G000300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I607"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="376" mass="38597" checksum="B7663B0135CD7E76" modified="2022-10-12" version="1">MAESDVKIADLTPEVEKKTESVPDAVVDPTPVRTADSAPEKEESNVEPKVEAPEPTEVTTSGEPVPHAPAAEPSAPAPAADLLAPAPVEESPVAPAEESKEVKALETETPAELKESSPAVDTKAVEPASKSDHSTLFQKLKKTFEFPKSHKSKESPSKEAPVPADTTEAVLPSEVPAPAPVAEEAEAAVETSPAPAASEPKPTASDKVAEKVSEGKGFFNKVKKSFFTKSHSFSGSIPDSKSGAGTATPPPAIAEVSKDAETVPTPAASGTSVTPAPEPAGEASPAPGPVEVPSSAVETAPTPVAEVATPVTDTFTPAEESKDAPKETVEEKGAVKEEKPKNKFFQKIVRRLLPKNTHNSPPSAAPAAAPVVAASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I798</accession>
    <name>A0A8T0I798_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G060500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I798"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12225" checksum="3296B5F4366C80AD" modified="2022-10-12" version="1">MSLVVSKYFVALQTNPKALYNHNPTTPDTIFSTQCNHGRLVRESQTTSEGSRTASSFDVEPHGPWAMATARTEIMKREDKLERQGGGGRSKAASRRVLSCTWNDPGKGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8V0</accession>
    <name>A0A8T0I8V0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G056100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="383"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="914"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="392"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="914"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="932"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="960" mass="104816" checksum="77BE60B2E81033A4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9H5</accession>
    <name>A0A8T0I9H5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Calcium-activated potassium channel BK alpha subunit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_4G165600</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9H5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005267">
        <property type="term" value="F:potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003929">
        <property type="entry name" value="K_chnl_BK_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047871">
        <property type="entry name" value="K_chnl_Slo-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048735">
        <property type="entry name" value="Slowpoke-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10027:SF39">
        <property type="entry name" value="CALCIUM-ACTIVATED POTASSIUM CHANNEL BK ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03493">
        <property type="entry name" value="BK_channel_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22614">
        <property type="entry name" value="Slo-like_RCK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21014">
        <property type="entry name" value="Slowpoke_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="Calcium-activated potassium channel BK alpha subunit" evidence="13">
        <location>
            <begin position="97"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="15">
        <location>
            <begin position="442"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="domain" description="Ca2+-activated K+ channel Slowpoke-like C-terminal" evidence="14">
        <location>
            <begin position="678"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="364"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="279"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="325"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="366"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF03493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF21014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF22614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0580334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="742" mass="83753" checksum="E03CCB8EFF6D41AF" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9I7</accession>
    <name>A0A8T0I9I7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutaredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3 9">1.11.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G111400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62624"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:10730"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.25" evidence="3 9"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="11">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0579629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="20036" checksum="0489FB1C1AAF3F55" modified="2022-10-12" version="1" fragment="single">LTIGVSSVPEADLCYFDKEGNVHTVKVSELTRAKKVVLFAVPGAFTPTCSTQHVPGFVAKAEELRKAGVDVLACVSVNDAFVMRAWGEQMKVGENVLLLSDGLGKFTKAMGATVDLSDKPVGLGVRSRRYAMVVDDGVVKALNMEEGGAFTHSSAEDILKCLQKHKASNVECSAGQNVMVCLISHHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBG7</accession>
    <name>A0A8T0IBG7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Acyl-[acyl-carrier-protein] desaturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_4G198000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="15">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBG7"/>
    <dbReference type="OrthoDB" id="1924153at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045300">
        <property type="term" value="F:stearoyl-[ACP] desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01050">
        <property type="entry name" value="Acyl_ACP_Desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000002">
        <property type="entry name" value="Stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005067">
        <property type="entry name" value="Fatty_acid_desaturase-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155">
        <property type="entry name" value="ACYL- ACYL-CARRIER-PROTEIN DESATURASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155:SF9">
        <property type="entry name" value="STEAROYL-[ACYL-CARRIER-PROTEIN] 9-DESATURASE 7, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03405">
        <property type="entry name" value="FA_desaturase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000346">
        <property type="entry name" value="Dlt9_acylACP_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="14" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12 15" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="binding site" evidence="15">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000346-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0580772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="411" mass="45720" checksum="DCD73F3492BDF8BB" modified="2022-10-12" version="1">MAAMAVSAPVGASSCLGAASSAWKGERVEGKLSMGRRAVRAGGMEVVMTATLPPKLQGAGVSGGKPPAEKHALRMHSIAPEKLELFKSLEGWASETLLPYLKPVEKCWQPQDFLPDPAAEDFLDQVRELRERSACLPDDYMVCLVGDMITEEALPTYQTMLNTLDGSRDETGASPTPWGVWTRAWTAEENRHGDLLNKYLYLTGRVDMKQIEKTIQYLIGSGMDPQTENNPYLGFVYTSFQERATFISHGNTARHAKEHGDAKLAQICGIIAADERRHENAYTKIVEKLFELDPDGAMLAFADMMKKKIAMPAHLMYDGQNDHLFDDFSLVAQRTGVYTARDYADIMEHLVKRWDVAHVRGLSPEGEAAQQYVCGLPPRIRRLDERAQAKVKKGPKTGSFSWIFNREVALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC22</accession>
    <name>A0A8T0IC22_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">40S ribosomal protein S24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G240500</name>
        <name evidence="8" type="ORF">KC19_4G243100</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC22"/>
    <dbReference type="OrthoDB" id="10251131at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.3370:FF:000001">
        <property type="entry name" value="40S ribosomal protein S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00545">
        <property type="entry name" value="Ribosomal_eS24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053709">
        <property type="entry name" value="eRP_eS24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_eS24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018098">
        <property type="entry name" value="Ribosomal_eS24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_uL23/eL15/eS24_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10496">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="Ribosomal proteins S24e, L23 and L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00529">
        <property type="entry name" value="RIBOSOMAL_S24E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="104"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0581294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15465" checksum="699149BB8A44563D" modified="2022-10-12" version="1">MAEKACTIRTRKFMTNRLLARKQFVIDVLHPGRANVSKAELKEKLTKLYEVRDPQSIFVFGFRTQFGGGKSTGFGLIYDSVDSAKKYEPKYRLIRNGLATKVEKSRKQIKERKNRAKKIRGVKKTKAAGDAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFA4</accession>
    <name>A0A8T0IFA4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G231700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small hydrophilic plant seed protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFA4"/>
    <dbReference type="OrthoDB" id="540492at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038956">
        <property type="entry name" value="LEA_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022377">
        <property type="entry name" value="Sm_Hydphi_plant_seed_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000389">
        <property type="entry name" value="Small_hydrophilic_seed_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671">
        <property type="entry name" value="EM-LIKE PROTEIN GEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671:SF19">
        <property type="entry name" value="EMBRYONIC ABUNDANT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00477">
        <property type="entry name" value="LEA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00431">
        <property type="entry name" value="SMALL_HYDR_PLANT_SEED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9373" checksum="5AB07F4835EC37D8" modified="2022-10-12" version="1">MASREELDQRAQAGETVVPGGTGGKSLKAQEHLAEGRSKGGKTRASQLGHEGYAEMGKKGGLASNGADPNESAEAQDIDIDESKFTNIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFS8</accession>
    <name>A0A8T0IFS8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G000200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="936"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1012"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1057" mass="121722" checksum="C863DA7E64B759D9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH15</accession>
    <name>A0A8T0IH15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G050100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="611"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="465"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="620"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="630" mass="69422" checksum="3BB0E6D33A4F1B5D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK32</accession>
    <name>A0A8T0IK32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Repressor of RNA polymerase III transcription</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G094300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the MAF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000994">
        <property type="term" value="F:RNA polymerase III core binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016480">
        <property type="term" value="P:negative regulation of transcription by RNA polymerase III"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1000.50:FF:000003">
        <property type="entry name" value="Repressor of RNA polymerase III transcription MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1000.50">
        <property type="entry name" value="Repressor of RNA polymerase III transcription Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015257">
        <property type="entry name" value="Maf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038564">
        <property type="entry name" value="Maf1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22504:SF0">
        <property type="entry name" value="REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09174">
        <property type="entry name" value="Maf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037240">
        <property type="entry name" value="RNA_polIII_Trep_MAF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0678">Repressor</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR037240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="227" mass="25613" checksum="5E73E3F646856D12" modified="2022-10-12" version="1">MKFLEYTPLARINTFLSHVDVGGCMIQGVMEAYSCKLAGVDKKLSRSLEQEVVDSLAYSPLDLSTSPVGPLSNTASRRTLIYLILTLNHMYPDYDFSMLRPHHFTKEHGVLAAKQKIDVSLVEASKIWSTEVGEETTLMDSIWNGIDEVMNLEECEVYSYSPDAEGDPFADTGSIWSFNYFFYNKKQKRVLYFSSRCASKQSMDSFSSDDGSGEWDMDFVDGMDLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK89</accession>
    <name>A0A8T0IK89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-acylglycerol-3-phosphate O-acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.51</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Lipid droplet-binding protein CGI-58 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G091200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055088">
        <property type="term" value="P:lipid homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006654">
        <property type="term" value="P:phosphatidic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000124">
        <property type="entry name" value="Probable 1-acylglycerol-3-phosphate O-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886:SF29">
        <property type="entry name" value="PUMMELIG, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42886">
        <property type="entry name" value="RE40534P-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035751971" description="1-acylglycerol-3-phosphate O-acyltransferase" evidence="13">
        <location>
            <begin position="23"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="14">
        <location>
            <begin position="119"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00075419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0582853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="422" mass="47637" checksum="1F58C03D8E80CFAA" modified="2022-10-12" version="1">MGSLMVGCCWCWCWEFLVVVLAPRSMKMTATEAATEAATEATQPSWMSTWQQYLRWSPTSKQEVLASENRLFSLLKTPYIQEQVNIGTGPPGSQVRWFRSVSNEPRFINTITFERENAPTLVMVHGYGAAQGFFFRNYDDLAQRFRVLAIDQLGCGASSRPDFTCKSTEETESWFVDSLEEWRRTKKLDHFILLGHSLGGYVAARYALKHPEHVQHLILVGAAGFSEESDRIIQFRSTWKGAVANFMWDRNLTPQKIVRGIGPWGPALVRKYAGVRFGTYTTGNMLNEQESKLFSDYLFHTLAGRASGELCLKYIFSLGAFARTPLITSAPDWKVPTSFIYGMDDWMDWGGAQEARKKMPVSTELLRVPQGGHFVFLDNAPGFYSAIVYACRHFLPGLAVKHLPEGLIQVPHPNNKIDTGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILS7</accession>
    <name>A0A8T0ILS7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G193700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILS7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="210" mass="24113" checksum="C398BB4B885ACC0A" modified="2022-10-12" version="1">MGDLCIFAFLRMNFAMCTPEIDHWRILETTVNVLPGLPTLLRLADCEYVANFRAEPKHQPGEDYNAWEGRGESYPKLFRPPAETLLPNEDHRVRCCDDDPIPYHEGSNIMGPGPLLLKKQLPLTARELHVKAMLDVADGHRRSLRRQTIVPLARNSLAAATRKSFRKLSYVPPTVPQDWLAEDKREKKGPPHPPTRTINEFNDFEYNPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMZ3</accession>
    <name>A0A8T0IMZ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G261000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11985" checksum="8F0D3D0AA9307A46" modified="2022-10-12" version="1">MSSSIRMTHLSTVILMEWIQENYGSPENEDNDELIVFWILSQTCSWARQYSRNFPRMIGNAHMNYLFSLEDCRLYYNPVMYDYDNDEVNFAAFWSRVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IND8</accession>
    <name>A0A8T0IND8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branchpoint-bridging protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G204700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the BBP/SF1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IND8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02395">
        <property type="entry name" value="KH-I_BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.60.10:FF:000011">
        <property type="entry name" value="splicing factor 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.10:FF:000047">
        <property type="entry name" value="splicing factor-like protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045071">
        <property type="entry name" value="BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055256">
        <property type="entry name" value="KH_1_KHDC4/BBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032570">
        <property type="entry name" value="SF1-HH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047086">
        <property type="entry name" value="SF1-HH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208">
        <property type="entry name" value="RNA-BINDING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11208:SF45">
        <property type="entry name" value="SPLICING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22675">
        <property type="entry name" value="KH-I_KHDC4-BBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16275">
        <property type="entry name" value="SF1-HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="8" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="CCHC-type" evidence="14">
        <location>
            <begin position="459"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="13">
        <location>
            <begin position="637"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="71"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="516"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="713"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="886"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="101"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="571"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="582"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="721"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="779"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="802"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="847"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="12">
        <location>
            <begin position="886"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="900"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0584346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="942" mass="96911" checksum="FA6AEB3B9B972BEE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPC3</accession>
    <name>A0A8T0IPC3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G199600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013989">
        <property type="entry name" value="Dev_and_cell_death_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46444">
        <property type="entry name" value="DCD (DEVELOPMENT AND CELL DEATH) DOMAIN PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46444:SF19">
        <property type="entry name" value="OS02G0745600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10539">
        <property type="entry name" value="Dev_Cell_Death"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00767">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51222">
        <property type="entry name" value="DCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DCD" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6676" checksum="1DD92E1A8ACABBAB" modified="2022-10-12" version="1">MRIAPGAAIFLFNFRTKCMHGIFEATSHGGVHIIREAFGGKYEAQVSSLYPLFEILGGADM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR25</accession>
    <name>A0A8T0IR25_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G000200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47202:SF2">
        <property type="entry name" value="G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47202">
        <property type="entry name" value="HISTIDINE-RICH GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="239" mass="26380" checksum="C28A2DDD3E2F00F1" modified="2022-10-12" version="1">MGWEGWYGDGMGMGWDGWDGMGWDGMGWDGWDGMGGWAGMGWDGMGWDGMDGMGMGWDGMGWDGMGWDGMDGMGWDGMDGMGWEWELGWDGIGWMGWDGMGWDGWDGRDGMGWDGRDGMGWDGWDGMVWDWMGSDGRVGGMGWDGMGWDGWDGMGWDGMGWDGMGWDGMGWDGMGWMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGMGWDGRDGMGWDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRI1</accession>
    <name>A0A8T0IRI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G084100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001313">
        <property type="entry name" value="Pumilio_RNA-bd_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051728">
        <property type="entry name" value="RING-FYVE_E3_ubiquitin-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879">
        <property type="entry name" value="CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14879:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00806">
        <property type="entry name" value="PUF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="33"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="5">
        <location>
            <begin position="834"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="552"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="629"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="797"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="882"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="920"/>
            <end position="987"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="992"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1092"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="578"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="637"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="662"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="683"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="705"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="739"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="760"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="888"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="933"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="992"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0586350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1143" mass="121364" checksum="2E9AE013FC0E8C58" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRT1</accession>
    <name>A0A8T0IRT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Subtilisin-like protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G016900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02120">
        <property type="entry name" value="PA_subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.2310:FF:000001">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000006">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.30.30:FF:000005">
        <property type="entry name" value="subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046450">
        <property type="entry name" value="PA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041469">
        <property type="entry name" value="Subtilisin-like_FN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17766">
        <property type="entry name" value="fn3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52025">
        <property type="entry name" value="PA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035804990" description="Subtilisin-like protease" evidence="9">
        <location>
            <begin position="28"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="12">
        <location>
            <begin position="43"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="10">
        <location>
            <begin position="157"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="11">
        <location>
            <begin position="396"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease fibronectin type-III" evidence="13">
        <location>
            <begin position="689"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="228"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0585501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="799" mass="83940" checksum="A0FC6F9A5464F516" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWV7</accession>
    <name>A0A8T0IWV7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Mitotic spindle assembly checkpoint protein MAD1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G155100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWV7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000776">
        <property type="term" value="C:kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072686">
        <property type="term" value="C:mitotic spindle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051315">
        <property type="term" value="P:attachment of mitotic spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007094">
        <property type="term" value="P:mitotic spindle assembly checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.457.60:FF:000004">
        <property type="entry name" value="Mitotic spindle checkpoint protein MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.457.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008672">
        <property type="entry name" value="Mad1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168:SF0">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23168">
        <property type="entry name" value="MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05557">
        <property type="entry name" value="MAD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75704">
        <property type="entry name" value="Mitotic arrest deficient-like 1, Mad1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0498">Mitosis</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="199"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="435"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="532"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="638"/>
            <end position="665"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0587306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="770" mass="86730" checksum="385F35C344DD0FBC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1L5</accession>
    <name>A0A8T0J1L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Epidermal patterning factor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G274400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1L5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010374">
        <property type="term" value="P:stomatal complex development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039455">
        <property type="entry name" value="EPFL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109:SF4">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17181">
        <property type="entry name" value="EPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035887922" description="Epidermal patterning factor-like protein" evidence="6">
        <location>
            <begin position="24"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0588858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="148" mass="16043" checksum="DCAFA64C778EF76B" modified="2022-10-12" version="1">MPIPPSCRILLLLTMVPIVAVAGRRIPAAPLIASLTPTPQVELSAQETGSEGVTWEHGQHHQEYVSRAPPPSRKLFRGNVKMEDSIYGHRLLVGSAPPSCQGKCGSCVPCTPIHVSIGSSPVHAGSVTQQEYYPEVWRCKCGNKFFMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4J4</accession>
    <name>A0A8T0J4J4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G107300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4J4"/>
    <dbReference type="OrthoDB" id="1946at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007434">
        <property type="entry name" value="FemAB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47017">
        <property type="entry name" value="ACYL-COA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47017:SF1">
        <property type="entry name" value="ACYL-COA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04339">
        <property type="entry name" value="FemAB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="481" mass="54661" checksum="7CE525C816B67297" modified="2022-10-12" version="1">MAALAIQAHGHGLLQRHGFSCSHLPLHMNLSLAYPSTLRKCPVIPTALFWGERRSSKRVTPRPNREQFVISAEQVSQQAKQETARESDASPLTLTVSVVSSISLVSAEAWDLCALEAAGPEAVNPFVSHAFLSSLEDSKSAVAEEGWLPQHLVARDASNEVLGVVPLYLKSHSYGEYVFDHAWANAFFRYGGKYYPKLQCCVPFTPATGPRILVRTGSFREQVFDGLAKCMQQLTDQMKASSLHITFPERQEWERVAKMGYLQRMGVQYHWKNRNYSSFDDFLMDLKQSKRKNIRQERKKVVAQNLTLKRLRGDDIKPHHWDAFYTFYRNTTDNKWGQAYLTREFFHLMGERMGDRVLLVVAEDKGDLVAGALNLIGGDTLFGRNWGCKEYAHYHALHFEACYYQAIEAAIEMKLQTVEAGAQGEHKIQRGYLPTATYSAHYLPDPDFHDAIESFLLRENVQTKMALQYLQEASPFKDGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4N9</accession>
    <name>A0A8T0J4N9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_1G064700</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4N9"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000001">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 16 17" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4 17" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12 17" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 17" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="15 17" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="6 17" id="KW-0934">Plastid</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 17" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>4</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0590019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="28355" checksum="A468CC43289C840F" modified="2022-10-12" version="1">MAAATAMHSTALAGQSLLKPVNELARQVGSSESRITMRKSASKSAGSDSIWYGADRPKWLGPFSGETPSYLNGEFAGDYGWDTAGLSSDPETFARNRELEVIHARWAMLGALGCLTPELLAKSGTKFGEAVWFKAGAQIFSDGGLDYLGNPSLVHAQSILAIWACQVILMGAVEGYRVAGGPLGDVTDPIYPGGSFDPLGLADDPDTFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLNDHLADPVANNAWAYATNFTPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7M1</accession>
    <name>A0A8T0J7M1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G139500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7M1"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12325">
        <property type="entry name" value="RRM1_hnRNPA_hnRNPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12330">
        <property type="entry name" value="RRM2_Hrp1p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000051">
        <property type="entry name" value="Heterogeneous nuclear ribonucleoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033">
        <property type="entry name" value="RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48033:SF10">
        <property type="entry name" value="RNA-BINDING PROTEIN SQUID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="96"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="185"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="42"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0590969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="44613" checksum="C7FF95CF727D2A9D" modified="2022-10-12" version="1">MEGGGDEERMHEVAPDLNGTLEDNYVDDDDQQQQDADPLHGDEDDDPLQGDEDEHEHEHEHEHGYQNGGSAKDAMVESDPKDSPTASQGKASSSGGKIFIGGLSWDTSTDNLQSHFKKYGEIIDAVIMKDRSTGHPRGFGFVTFADPAVCDNVVLDKHVIDGRTVEAKKSVPRENMAASKGPKTKKIFVGGIPPSITDDEFKSYFAGFGSVVEHQIMQDHSTGRSRGFGFVTFDSEQTVEDILAHGKMHELGGKQVEIKKAEPKRAIQDSPGGGYPGGRGGAYGASAGGYGGYDGGYGGSGSAGGYGGSYRSGGYGGRGGYGSAGYGGGYGGGYGAGGGYGGGYGGGLGVAGYGTGVGGGYGGSLGYGSGAGYGAGMMGGYGDAADGYGSMGYGGYSGTGYGAGYSSSGGYGSGYASSRGYSGSGGGSSHGRYHPYGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8X6</accession>
    <name>A0A8T0J8X6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G157600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8X6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="10575" checksum="51DA48BFC6CD7DF0" modified="2022-10-12" version="1">MNTCDCPGLLSSCFVAELSNFIPSSFIKCDSSDSSNMVDSSGQASDQSLIMAKKLVYKEDFEGVIVPNSFKVKPSTASGLQGGQLTLFIPFIRKISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9B0</accession>
    <name>A0A8T0J9B0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G197300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9B0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="13557" checksum="CC7A3E5DE53B1065" modified="2022-10-12" version="1">MVLPIIKRSKKLWRSTCILMQLRLYTKPRYVLPYLVINYPVNAQLLNNNTPHFDSQIVVAWKSWNVSLNHLDLRILYKSHSWSHSPEIVKGKCMLRKIQLVTVEICPLSMVPSSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9I1</accession>
    <name>A0A8T0J9I1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G184700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9I1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="5557" checksum="4625C7E57A9243E2" modified="2022-10-12" version="1">MAKDNGKCGANCDCAAGTCAKENGKCGANCDCAAGTCAKENGKCGANCDCAAGTCAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA38</accession>
    <name>A0A8T0JA38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G246700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="185" mass="19938" checksum="9346AED19E79B20E" modified="2022-10-12" version="1">MFRHGTALQTQPHGMFRFETDQQRHLDNGGHVPERNRRAEAERKACSGVESGVQTSPGPGFMHLGAGGGCLRALCCCCCCCCCWCCCGVVSDAARDRLRSAFLSRGGVLRGRHRTFFLASAHVTRFLIIAGSRHFRTSFSTFALPPSGFSSRPGVCDALRSVAVAGGLWRNSLQRTQNGSGSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAI5</accession>
    <name>A0A8T0JAI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G238900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="13836" checksum="9AAEF0D54ABE9346" modified="2022-10-12" version="1">MPLMAQGHMLLRTAWSSAAVLGNPPLRTPCKNLIHCRKRRCHSLPLLSSFNHPASTPSLPQVTDTPPHPLEPKLTQVTTQNSLLWNLKQAPKHQPNHTIPHSEPKNSLPLSLSSRKTRLKTSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCN3</accession>
    <name>A0A8T0JCN3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Early light-induced protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G280700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ELIP/psbS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCN3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="80"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0592783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="234" mass="25304" checksum="523E5304F072FFC8" modified="2022-10-12" version="1">MAAAMTNMVMTVRADGLQALPLLQTSKFSKVAGARVMAAPRVPRTLLAGSVRCESGKNPIADVREAVDRSTKKVITEDEILRNQETNESEKKSVMGTEPTSGAPWPRPEVERRPETGSKSFWSVFAFDGAAPETINGRLAMVGMVWAVVGEQMTGQTVVEQLVGPGQTGLLYFLVAAQVLTYASLVPIMSGESTDARRSGPFTARAERWNGRMAMLGFFSLVVTEMFTHSAIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCT8</accession>
    <name>A0A8T0JCT8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G269800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCT8"/>
    <dbReference type="OrthoDB" id="534912at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3430.10:FF:000005">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="entry name" value="Ammonium transporter AmtB like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029:SF10">
        <property type="entry name" value="AMMONIUM TRANSPORTER MEP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111352">
        <property type="entry name" value="Ammonium transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="160"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="348"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium transporter AmtB-like" evidence="9">
        <location>
            <begin position="24"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0592648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="487" mass="52397" checksum="C8D9366D15067E81" modified="2022-10-12" version="1">MSVPSAYNNTGGVTPDWLNKGDNAWQLTAGTLVGLQSVPGLVILYGSIVKKKWAVNSAFMAFYAFAAVLLCWVVWGYKMSFGDKLLPFWGKGGPVLSHTLLLNQAILPATVHYHSDGTLETGALAPLYPLATMVYFQFVFAAITVILLAGSLLGRMNFRAWMLFVPLWLTFSYTVGAFSLWGGGFLFQWGVIDYSGGYVIHLSSGVGGFVAAFWVGPRLNRDRERFPPNNVLLMLAGAGLLWLGWAGFNGGDPYSANIDAALAVLNTNVCAATSLLMWTIMDVMVFGKPSVIGAVQGMITGLVVITPAAGVVECWAAIVMGVCAGSIPWFTMMVVHKRWSLLQRVDDTLGVFHTHAVAGLLGGLLVGLFAEPTLCNYFLSVTGEQGGFYGGVGGIQFGKQLAGAFFIIGWNVVVTSIILIVIQFVVPLRMTQELLVVGDDAAHGEEAYALWGDGEKYDMTKHGNADFDDMTSFHGVDIRSRGPTVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4V9</accession>
    <name>A0A8T0G4V9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bulb-type lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G015000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4V9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035882811" description="Bulb-type lectin domain-containing protein" evidence="1">
        <location>
            <begin position="34"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="2">
        <location>
            <begin position="227"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="348" mass="38601" checksum="B43053CB7C337BF6" modified="2022-10-12" version="1">MTRSMIHVTGLLLLHVGAIILLNVENPCTKVEAYEIVFSTDLTTDFAKGSIDVPSLIRQDWLTLPLIGFCGLASKFSTAHKFDTSTIRGTFYTTFEYLTQDCTAEYKRDNNTCALLTAAFAVCLGFPLDRRTCNHPWGYCSNFNFRLSYMWVPNVTLPGLPKLSNLPVHQLQSSTSELARSGTSDPAALATIHQDIESLREASVRASATGGRLDTGCDWRYSSLVPVAWDGVQNVLTVGQSLQSPDSTYNFIMQQDCNLVLYKKGADGKYEFNARWASYSHFNDPFFHNCSTVLQPNGNLVVLDPWGFPRWSSNSTTPSWYTSALAVLRNGSVAVYEMNSGTVLWSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6M7</accession>
    <name>A0A8T0G6M7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G065800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6M7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="128"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0554137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="485" mass="55414" checksum="2F7FB1379543FD4D" modified="2022-10-12" version="1">MAKSKLCVARAQERKATGRVTFSHNELKALSKVCLEAYHSEEVNFLIDVNAKNQWLRTVIGHEDLHPTTWTEANDELLSKIVIQSNLVPYDPFWSKPLAKKDGTNFKRVHFPSSVLKDALDEFKPLATKLQEWICSGKTCEIGMHSREQLVTSKWFWEMKEDEVDPIKELSTAGIWLITWHGGRFIQKETPDNSEVEIVRRFSHPHIVYCFGLLYRETRRPAYFMEYMENELHAFMGDRKRADNEKPPFLLHESVSILLQIARAMEYMHEVVNVVHCDLKSANVLITEITISDTVKHYLVKVADFGSARSGNSGSGSMTGFVAGNGTTPYTAPEALQQQQQFKDIELKDKTAYISYPHKIDVYSFGIISFEVLTGDTYEYFQLYRSSPTKFKAGVIGGTIRPSLCREWQNVKFLQDKGLKLLIESCWHPDPSKRPTFVKICKDLDCALERLSGVSSKNSLLDRVFRKLPALTSHLSCQSQSSTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6X7</accession>
    <name>A0A8T0G6X7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G040800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6X7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10289" checksum="5C89CB03661B0ED8" modified="2022-10-12" version="1" fragment="single">PHVACGLRLDPVGVHALPAPLPPRRSLAVPLLNRQGRHSSAAMGRSITSELRGAVELQLTISLGGLRPLGWVIGGGLCLRATSAPSCGPSHASWVGSGRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8W8</accession>
    <name>A0A8T0G8W8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G119800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8W8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="183" mass="21325" checksum="18A13BE2F05662F2" modified="2022-10-12" version="1">MSRSRSRRGDARKLRRWGWRGRKGRCKGQARDDHHLGGLSRHVRHAGASEFGHQPTNRREIPLRKPTTCSFRCARRVVETSHIIKSRGCRMKESQLPRLPENSGSSRGHKKRGKLPQPPKSRAISALSLPLSRSLSLELSTRILNHHLFSFFRPFRLRFTRFSRMNSCGYHVRSRFLMSGFWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G926</accession>
    <name>A0A8T0G926_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G087600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G926"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16937" checksum="5ED20508BEEF2E2C" modified="2022-10-12" version="1">MAPYIVYYDTWRVCPNCIHTKLVAQFYEDLWTFSQCEDHPIPIQPLEVPNDEETNLVEEFECKCLECEQNMETTRWFKCLIANMISEVVENEDSRSEKEQVDSITKETHGSLSIAFQCGSEDEDINQESHGPSLTMEFQCGYEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9Y0</accession>
    <name>A0A8T0G9Y0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G109800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000322">
        <property type="entry name" value="Probable disease resistance protein At1g63360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058922">
        <property type="entry name" value="WHD_DRP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766">
        <property type="entry name" value="PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766:SF30">
        <property type="entry name" value="TIR-NBS TYPE DISEASE RESISTANCE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23559">
        <property type="entry name" value="WHD_DRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0611">Plant defense</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="235"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="532"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="532"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1388" mass="157130" checksum="706D9FDC4428E809" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA43</accession>
    <name>A0A8T0GA43_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">L-gulonolactone oxidase</fullName>
            <ecNumber evidence="4">1.1.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G067300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-gulono-1,4-lactone + O2 = L-ascorbate + H2O2 + H(+)</text>
            <dbReference type="Rhea" id="RHEA:32363"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17587"/>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
            <dbReference type="EC" id="1.1.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; L-ascorbate biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.8" evidence="4"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050105">
        <property type="term" value="F:L-gulonolactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055154">
        <property type="entry name" value="GULLO2-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010030">
        <property type="entry name" value="GULO_Plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01677">
        <property type="entry name" value="pln_FAD_oxido"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF67">
        <property type="entry name" value="L-GULONOLACTONE OXIDASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22906">
        <property type="entry name" value="GULLO2-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0060">Ascorbate biosynthesis</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035848243" description="L-gulonolactone oxidase" evidence="9">
        <location>
            <begin position="28"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="10">
        <location>
            <begin position="59"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0554152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="602" mass="65737" checksum="3D0EE6418B5FF04A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBY3</accession>
    <name>A0A8T0GBY3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G174100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBY3"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097546">
        <property type="term" value="C:ciliary base"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019894">
        <property type="term" value="F:kinesin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042073">
        <property type="term" value="P:intraciliary transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44117">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44117:SF1">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="203" mass="22252" checksum="957719A32DAD63E2" modified="2022-10-12" version="1">MASPNFCKSPPFPRPSGSLQATASLPPRDPADDLYEGYNDYDPQLHQIYTGSQSQIGLRESFESKMDSIGVYDHVPVYSRSSSASDIQGPAFSRTLTPHTTASMMWRPPSTSMSSRAQYNPYSSTDSSRPMTAIRAAGYSSRGSKFDPMNQASTNSSLGAQKKEEVNPEYQCREMERAVNQLLEASAVASLAVRPAYSRLLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC65</accession>
    <name>A0A8T0GC65_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G067500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC65"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055308">
        <property type="entry name" value="TEX47-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24787">
        <property type="entry name" value="TEX47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15805" checksum="C8093294CEC6AA42" modified="2022-10-12" version="1">MNIMQARPNMLDATLEAAALKRGPSISRMLYAARIPEDKHPEPDKTRIASWHELTLKQVGMLLRMSGFLIVYPTCVLHLLEVSYSHRSSPQSPNLMIQDDDDATLSQKHRLLCILRKYRGGISGGCRYWSGWKQGVALAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCW7</accession>
    <name>A0A8T0GCW7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G143100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The B regulatory subunit may modulate substrate selectivity and catalytic activity, and may also direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the phosphatase 2A regulatory subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCW7"/>
    <dbReference type="OrthoDB" id="6274823at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000569">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000609">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000009">
        <property type="entry name" value="PP2A_PR55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018067">
        <property type="entry name" value="PP2A_PR55_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11871">
        <property type="entry name" value="PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037309">
        <property type="entry name" value="PP2A_PR55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00600">
        <property type="entry name" value="PP2APR55"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01024">
        <property type="entry name" value="PR55_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01025">
        <property type="entry name" value="PR55_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5" id="KW-0853">WD repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="169"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="444"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="172"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00034298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU331113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0555082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="58986" checksum="BF1DCD847EE2D914" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFC2</accession>
    <name>A0A8T0GFC2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">fructose-bisphosphatase</fullName>
            <ecNumber evidence="3">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-fructose-1,6-bisphosphate 1-phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_11G095500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="3"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030388">
        <property type="term" value="P:fructose 1,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005986">
        <property type="term" value="P:sucrose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000009">
        <property type="entry name" value="Fructose-1,6-bisphosphatase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="FRUCTOSE-1,6-BISPHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556:SF12">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035925935" description="fructose-bisphosphatase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class I N-terminal" evidence="10">
        <location>
            <begin position="159"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Fructose-1-6-bisphosphatase class 1 C-terminal" evidence="11">
        <location>
            <begin position="343"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0557014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="487" mass="54293" checksum="2CA07D4F2EB0EE69" modified="2022-10-12" version="1">MNAYLVLFLICFVPLATHRYAQTQKPSIPEYPASKPLEPPPPPPTPPSRSLLYRFFAFLFRKTFTSSSERRNRKPPPSPPPSSEYTYYASPPVVKVPQKPSPVSRWFSTSARARARRAPPPPTSQGSYFRRAPLNSYAAARNAEGVITLTAFLGTEGSNVDVDLVVLMAHIQGACKHIGSILSTPKDLQSTPSAYDPPFGNRERENPRSLRTLSNNILHMALRSSGKVAAISSEEDDAPFWFGDSGPYVVVFDPLDGTQAFDELTPTGTMFSIYYRLREADHLPLGQKAAINVMQRGERLVAAGYGIYSSATMMCFSVGTGLHGFTLDSDVGEFVLTHPDIRIPERGSVYSINDGRYFDWSAQLRHYVDTIRQGRGQNSRRYSAKYISSMVADLHRTMLYGGICMNPRAHLHLVHEANALSFLVENGGGRAIDGRRRILEIQPAHLHQRLPLFLGSRADVSELESYGDVQQVININPEYDDDDDYFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGB4</accession>
    <name>A0A8T0GGB4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G001200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGB4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="80" mass="8757" checksum="92DC8ED5F4E572BB" modified="2022-10-12" version="1" fragment="single">FHNTIQCNSIQFNSIQFNSALEVIHSSTHIYIYIYMREGGSLYLPISLISLSVCLSVSLSRPVQSSPVQSSGCSVCLSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHL9</accession>
    <name>A0A8T0GHL9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G000700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHL9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035820710" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="53" mass="4787" checksum="3001DF1811F9372D" modified="2022-10-12" version="1">MGVGVGVAVAVAVAVADAGGGGGAGAGGAKLGEGFCKPPKSVCCCVCARYCLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI96</accession>
    <name>A0A8T0GI96_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_10G048400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000162">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035754943" description="Protein kinase domain-containing protein" evidence="16">
        <location>
            <begin position="29"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="452"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="516"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="545"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0558720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="845" mass="94375" checksum="D61F7B470C23C48B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ05</accession>
    <name>A0A8T0GJ05_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G105000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF2">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="537"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="91"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="9">
        <location>
            <begin position="403"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0559441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="570" mass="63012" checksum="0B8078B6E8463626" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJY3</accession>
    <name>A0A8T0GJY3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G096400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJY3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12184" checksum="B1ADB3AA4FAB303D" modified="2022-10-12" version="1">MSRSLESRSRRNPNLEPNVDGRRPRLSRWGIRVRRRRVKLQVSPLLGYLRGAYRMDPRLPGSKLGPLLAKLQFSCKRARRIHSIQASYESYEQAQPLLDSNPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMP0</accession>
    <name>A0A8T0GMP0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G169100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39596:SF3">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="810" mass="92745" checksum="82360636EA6B83AB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN01</accession>
    <name>A0A8T0GN01_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G024800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN01"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035946793" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="80" mass="8948" checksum="F9329690FF51D30F" modified="2022-10-12" version="1">MPRLLLQSPLCLIPKALILMGLHTSLHCWGSFTSQHRVNLGVDQRRIVVPDASMHSLKLSSRSASNRFEVGMVYGVVRSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNB1</accession>
    <name>A0A8T0GNB1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G185600</name>
        <name evidence="3" type="ORF">KC19_10G185800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNB1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11703" checksum="5ADCE258F1CB0CA6" modified="2022-10-12" version="1">MITTLGHLARPKFHRLDRCETFRVASRWERIIAKQNPGRAKLPTLRTGTRIVPKCSGNLNETTPPARVGTESARSMPSHSRSALPPHSTLTMPCHQFSVSTQPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP31</accession>
    <name>A0A8T0GP31_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G173600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="17576" checksum="361E4DD0E5311281" modified="2022-10-12" version="1">MGRLFLLNESFSMEVIFFKLVTLGIVGVCKLCTTPDGKIDFCKLGSVFGLEPDSITLCGVLFPTIHDLSYASWTQIKDILGVAGTEDDPVLVRGRLKIGASLVMGGILVIHKGTCEICKLRAPKYTSQVLNALRPNGHIFDQDGVQLIGTDTLEAGNYFLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQH8</accession>
    <name>A0A8T0GQH8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-CH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G091500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQH8"/>
    <dbReference type="OrthoDB" id="273089at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16495">
        <property type="entry name" value="RING_CH-C4HC3_MARCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011016">
        <property type="entry name" value="Znf_RING-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46214:SF16">
        <property type="entry name" value="OS10G0481450 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46214">
        <property type="entry name" value="ZINC FINGER, RING-CH-TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12906">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00744">
        <property type="entry name" value="RINGv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51292">
        <property type="entry name" value="ZF_RING_CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="RING-CH-type" evidence="6">
        <location>
            <begin position="223"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="410"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0559262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="47033" checksum="35EDC79BCE771F83" modified="2022-10-12" version="1">MLRRFNSLIKGPKGGQISDDELSELHVSLRPALSVDSSLFTSSQHHHVNPLQQQLARAREESLTRARSTRSTGQTSLNAGLLQQGSEEGQQAGRANGHVFVIGRVPEERLWKDGYENGTHNFHSSLDSKLSPVQSNTELRSGESHRSGENGSQFAFRSTPAPADAPRVLRTSSDAVTVDRANSQDLHTIVDIPDAQAGSVVDLDNVRKSVLTTGPGRTISSWSTDSAAEHCRICQQHTEEPLIELGCLCRGEMSKSHKSCIETWFKNKGTNKCEVCQHVASNIPAPETTPSSHFWVWRVGGAYGTGQAQGAQAAGARRVGMSLLVNRPVLLMIIRNHPLIPVMWLGLLAFMTYLFVDAINTSTIGYAAMPIGFLFGVLVVLGLGTAVRLVLEYAQERNVQRNIRLMESLGQPGNEDSVDGTDRPAAQNGPSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQT7</accession>
    <name>A0A8T0GQT7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G151200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="259"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0560058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1138" mass="128474" checksum="29ED47499C42C5DF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRZ3</accession>
    <name>A0A8T0GRZ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G037000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRZ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="13479" checksum="F3C91C08EBD1BA79" modified="2022-10-12" version="1">MAVLRTKQPLCLPFPSELVTWDAAQSEFGKSKACRLTSTVEVQRGHEVSCSVLFVRRLTLRSPAKLLDCALALTLRFASLTSTSGGSLFSGCLGEPGGSLRSPCSSTVLPTERSSPWVSLRTSVCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS01</accession>
    <name>A0A8T0GS01_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G125800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS01"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.830.10">
        <property type="entry name" value="Metalloenzyme, LuxS/M16 peptidase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050626">
        <property type="entry name" value="Peptidase_M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690">
        <property type="entry name" value="NARDILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43690:SF34">
        <property type="entry name" value="ZINC PROTEASE PQQL-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="LuxS/MPP-like metallohydrolase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M16 N-terminal" evidence="9">
        <location>
            <begin position="122"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="10">
        <location>
            <begin position="282"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M16 C-terminal" evidence="10">
        <location>
            <begin position="766"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="52"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0559732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1038" mass="117151" checksum="737B5F555CD875DC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSS2</accession>
    <name>A0A8T0GSS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_9G079500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Fe(2+)(in) = Fe(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28486"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:28487"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02435">
        <property type="entry name" value="CCC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035790934" evidence="10">
        <location>
            <begin position="26"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="281" mass="30085" checksum="F9BED906DAF97E02" modified="2022-10-12" version="1">MAMLAALHFLLPSLLLLQLTSDCEIIKPSGAHHRVQNFVIVVNSLPDKMCPATLHTERHFTAGEVVRDIVIGMSDGLTVPFALAAGLSGAAAPSSIVVTAGLAEVAAGSIAMGLGGYLAARSDADHYENERKREEDEIVQVPDTEADEVAEILANFGLEPNEYWPVVEALRKRPEAWVDFMMRFELGLEKPDPARALQSALTIAASYIIGGLIPLLPYIIISEALEALKVSIVVTLLALFIFGYVKGRFTGLRPVWSAFQTVFIGALASAAAFSIAKAISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTL0</accession>
    <name>A0A8T0GTL0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G190200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0563016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTL0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20339">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20353">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16630">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047545">
        <property type="entry name" value="BRcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051628">
        <property type="entry name" value="LUBAC_E3_Ligases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047546">
        <property type="entry name" value="Rcat_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047544">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770:SF47">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22770">
        <property type="entry name" value="UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26200">
        <property type="entry name" value="Rcat_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26191">
        <property type="entry name" value="RING-HC_RBR_RNF216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="305"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0563016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="609" mass="67848" checksum="6250D883B91045BF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU29</accession>
    <name>A0A8T0GU29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G115300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="380" mass="43772" checksum="44A207AABB3FFB06" modified="2022-10-12" version="1">MDFRAALWSDLPLEILEQVLSYLHVPDLCRYRTVCRRWDRLMCDPKFGSLCAQNTAKRDASLFAMRYSICGRRHEGWCFLDVNARRWYVVKDDGQGIRRNFPLENVRMDGGLVCQYLLNDLRPDRIIVYNPITQTHRKLPCTSKYFSKLTLVVDNISQSFKIILFNIPRKEPPILNTPLKLVYDSVTNEWKTSTNPFCISSGSKLLGSRVIFQGYVYNLRPLWRYNLVNDACENLDVPIRGEFSSACFVVSANRLFLVVWSKGGGLGFDDGGPSWSFQLSELKIPIMTRELLFEMPTADVVERFETGIKNRIPSLPEISAFSFGNSILFMSKSTGITAAFDVVTRAWDWNFPPNPLEYLPHEECEWVGEQMNLLLPCTPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWV5</accession>
    <name>A0A8T0GWV5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G096000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="23"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="377" mass="44221" checksum="167689786C1B04DA" modified="2022-10-12" version="1">MELRKLRRRGDEGTCVYQDVEWWSRLAPEICDMILEKLPTLERLRLRIVCKDWNCNVLQRLERKPYFVTIFRSTISSHYLSGVVVYDVVSKSLCFEPLPLKLHQTDQFYFRLPPFAVEGLILMNQPRARLRRKSWSVDVRKNQWCVYNIHTRTTHLLPRAPGCDRSSMCICGMMVDTSIKPHTFKLVVSNYCDEKRQIYDSASRTWSSHPKSNPNSNLWPYWNRGWYFCMCHKNCMYMATANAMDGVFVYSMEEDQWSRLSGSPFRGMEQTYLGVWDDRIFAVLHDPGAKSVTVWELIDATQQEWVEYAGCSKAQYEHLTENDEVVDYSCKIVSVFNAEYVLMYNWKTALNRSDALVLLNLKTSAWEPVVSKPNIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYG8</accession>
    <name>A0A8T0GYG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_8G045000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000015">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0430">Lectin</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="416"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0563607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="551" mass="62177" checksum="79CB474DE834030F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZV6</accession>
    <name>A0A8T0GZV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G021200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14609" checksum="197F0504EFAD5A02" modified="2022-10-12" version="1">MSVSYTRINTKNKPIMRIILPWQCAIIPVWLPVVTDCHILFSISHIEQFLFNNVGELKTLLTVLSISSLIIQTRFRIDVVMIGEEESGSIPVCLLCRAFRPRLDHHVHQSLITLLCSELQNATILSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1F1</accession>
    <name>A0A8T0H1F1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial</fullName>
            <shortName evidence="10">Glu-AdT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">GATB</name>
        <name evidence="12" type="ORF">KC19_8G067300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="function">
        <text evidence="10">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-aspartyl-tRNA(Asn) + L-glutamine + ATP + H2O = L-asparaginyl-tRNA(Asn) + L-glutamate + ADP + phosphate + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>L-glutamyl-tRNA(Gln) + L-glutamine + ATP + H2O = L-glutaminyl-tRNA(Gln) + L-glutamate + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1F1"/>
    <dbReference type="OrthoDB" id="1722066at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070681">
        <property type="term" value="P:glutaminyl-tRNAGln biosynthesis via transamidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032543">
        <property type="term" value="P:mitochondrial translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.410:FF:000001">
        <property type="entry name" value="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.150.380:FF:000001">
        <property type="entry name" value="Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="entry name" value="GatB domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="GatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004012">
        <property type="entry name" value="PRK05477.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004014">
        <property type="entry name" value="PRK05477.1-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF0">
        <property type="entry name" value="GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="GatB/YqeY motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="Glutamine synthetase/guanido kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="6 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asn/Gln amidotransferase" evidence="11">
        <location>
            <begin position="415"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0563888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="564" mass="61105" checksum="8A2672FEE77D4442" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1P6</accession>
    <name>A0A8T0H1P6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G074700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1P6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="28669" checksum="876D47AFB0220C4C" modified="2022-10-12" version="1">MANRSWVASVMFASKCAVSPLYFHEGKTKVDPHLASLMECEVVVKKISIYKTPLRTDLRQASAAQLNEQQGAGSSWTQLHHHFLIVEVSSPPHLHIIRAEKSGLDPEGFAGITVNIVPFIVEGKAAKEHHGRVVNLPIQLKKLIEILTAHHPDYDLLCDNCWKYADNTFKALEDTLRATTGSTEVQRQGQSQQLLANEGSMPPLIMPIERITQAAKVTTMIVSLGVLTTCAYKGLKWWMTREDEVKKEEVPAKQYCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2M9</accession>
    <name>A0A8T0H2M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_8G124200</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000129">
        <property type="entry name" value="Leucine-rich repeat receptor-like kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000468">
        <property type="entry name" value="PTI1-like tyrosine-protein kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000039">
        <property type="entry name" value="receptor-like protein kinase FERONIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052422">
        <property type="entry name" value="Auxin_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986:SF1">
        <property type="entry name" value="OS04G0685900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986">
        <property type="entry name" value="OSJNBA0070M12.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="687"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="514"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="1000"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="19">
        <location>
            <begin position="514"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="19">
        <location>
            <begin position="1000"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="715"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0564599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1038" mass="109411" checksum="444481C78369D1D5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2Y5</accession>
    <name>A0A8T0H2Y5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G034100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="192"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="207"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="39976" checksum="308255B00DB345AE" modified="2022-10-12" version="1">MSSAVAGTGDEDVSMATQQKRRWIKYYCEECKAWETREMFEVAKLGQGGVATQSTASPPGSSALWSWGCSKLVRHATFQTFRVQELNDADGHDAAPKLDFPSTESPASTEPVGQVQQPTHPGNTEATEEVSALQTVHAASQSNGSSQSKRPKRNVRSAYARDSVTDQATSPVNSQGGVTSSSPDEVVPDENGASTVHVKNNPKVTKNSKDSKDSKDSKESKDSKDTKDSKDSKDGEAATAAADTSVLESPAVIDAEHHENGVHKRPRRLTAGDRYLAQALQDEKPSRAAAKPLAEVNDVKPSQSSLEMKRPKRVTAGLRGAVLSAENAKSSPSPRVLAKKEEKKDAVHEVRTRSETAKKPSKKNRKLGDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5A1</accession>
    <name>A0A8T0H5A1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G066300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5A1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035769620" evidence="2">
        <location>
            <begin position="34"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="484" mass="53618" checksum="75415AE69F7D984F" modified="2022-10-12" version="1">MANFGPRRAPSKSSSIAFLMLCIAHLCISSSDGDEPVCRGSPTACSVDDSLSWLSDLRLWNPGDKGSQVSRSVLNSWCNDTVQDAARHVLELEDNVSVLMKEKLTCQQTMIEKENEWMEAESQLKMEYFRGKRELQRLCMEKEMLLRVKLGGERDAVAADLAHCRAMGQVMISAEECSYQKQLVLSKCEAEWDAGQLGLQKELVDRSLDENSQLGLCADSDTQQQNRMRWLEESLGTCRFERAQAQAVVDIGPEVEDLQLEQLRRSIKILSTLLVLSVTLCFGLAAALAVWIVSTVKGERGEGSSKLSTAMLGTYPQVLSSEEARRMLASLFEESKGDLSSILTSPDSTITNGADCVFLLVPLALASARKFALFGGGGDFTKQVEVAQDLVAHQLGKRLVIVLYHSGGHAFTQKTLDSIEMTAEKLVFEAVPKDRDFPSDDDVLVLWLNERYELQVSDSGGESELSEVITQQSWAHYLENRAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB74</accession>
    <name>A0A8T0HB74_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G058100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB74"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11908" checksum="C4A38E678091588C" modified="2022-10-12" version="1">MNAKMKCTKSLLNPAIPDAAYFCLETSNLSLTNENETSLASHTVQAELHEVYFWLRSCSHLIDNVHLAQLGFAEMSFCWCLALVIQELTLNVTRFVRSAGRGDSGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEI3</accession>
    <name>A0A8T0HEI3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G109200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13709" checksum="EA772E247600E98A" modified="2022-10-12" version="1">MGTLSKPEIDFMQFSLHSVGSKRSFIFVRIYYTQVSRQKYAASGIAGKLVGSTVFNSDFVHFILAFIRIIVVFRRVCLLLEVLSSLFSPLLTVKPKFSKLLLSHAVLSFKNIPIFEFRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGQ1</accession>
    <name>A0A8T0HGQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Killer toxin Kp4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G119400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGQ1"/>
    <dbReference type="OrthoDB" id="4177994at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.430.10">
        <property type="entry name" value="Killer Toxin P4, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015131">
        <property type="entry name" value="Killer_tox_Kp4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011329">
        <property type="entry name" value="Killer_tox_Kp4/SMK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09044">
        <property type="entry name" value="Kp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55221">
        <property type="entry name" value="Yeast killer toxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035820619" description="Killer toxin Kp4 domain-containing protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Killer toxin Kp4" evidence="2">
        <location>
            <begin position="18"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="13379" checksum="3CC56B10937D2C97" modified="2022-10-12" version="1">MASAMERKAVALLLSVLLLSAAGNTSALGINCRGSSNCGFQSSHTLSEINTKVQAIPDGNIFSNGVHIACVGNICAFLQNIASPGTKTAAQIKGFVTDLLNHGCTVCGSDPTEPGNDVNNGELTVNFVSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIF0</accession>
    <name>A0A8T0HIF0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plastid lipid-associated protein/fibrillin conserved domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G080600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIF0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039633">
        <property type="entry name" value="PAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006843">
        <property type="entry name" value="PAP/fibrillin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31906">
        <property type="entry name" value="PLASTID-LIPID-ASSOCIATED PROTEIN 4, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04755">
        <property type="entry name" value="PAP_fibrillin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastid lipid-associated protein/fibrillin conserved" evidence="3">
        <location>
            <begin position="97"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="293" mass="31668" checksum="089E33E3BCF1950B" modified="2022-10-12" version="1">MAMTLVSSSAVHPPCGLLAKGGPQFKWGNNRTGDVNLRFLRAELRSSCSRPLHLGKHGLYNHVTIGTDNTVQITRAMSSGSASEGTTTSAGGRTRKELKKLVMRAVTNTNRGKTATDEQKQYIYSLLVELEGQNPTADPINSPALSGRWALLYTAPIDERTSDKYAGTEEGPFLSRVKPVSLGTVRQSRSFQVIDTEGGAAENIAEFTFLGREGSLTIYGSVTKSAATEKGAVRVDVTFDSFVLKIGSIAFPSVSLSWISPKGWIETTYLDENFRIGRGDKGSIFVAARAKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKR4</accession>
    <name>A0A8T0HKR4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG009100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="12112" checksum="4A87C504760EF95D" modified="2022-10-12" version="1">MFGRRMFQLIPTKGACDGIHVIHGSSEQPRASQEMIPMKNGIATSIGIMVRMPERSLFAIDVDGWMRASTSLRWSWTPMNWQIEFEQMWRGMQLFEMDWWGGGGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL43</accession>
    <name>A0A8T0HL43_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_VG019900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL43"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001023">
        <property type="entry name" value="Os07g0541700 protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="5"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0571536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="202" mass="23189" checksum="A32388808914967A" modified="2022-10-12" version="1">MCPEFHPDKKLGQGAHGIVYKGVEADGTEKEVKNLTGQTQQRLDEFLNEVLLITGARHRNLVELKGCCLKDHRRLLLSEYVENNNLAEVIFEGVGAHDLNWGVRYRMCLGVAQGLHYLSESAEPRIIHRDIKAPNILLDKNLNPKIADFGLARLFRDEESHITTLHVAERMFGAGYWQFFLFILLQLEVTPRRKLRCMQLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMY9</accession>
    <name>A0A8T0HMY9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG060400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMY9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="38205" checksum="0F6464A24CDC673F" modified="2022-10-12" version="1">MLRNKLWASSPSKRSKWPGNPLWGLVLIHAPISGSKLWSKVHLAWKKMLKNLQEAPPINVADACQKPVWWGVDFKGGDFNLSQQDALSLYTRGLSTVGDLWCPVLNDIKPIDQIEDEFSLVGHEIPVMQAVGDWILNQYGNQLRRSDQETPPETWLGGYSLDDDNDPKFLIKTCKNWLPSPIGRPFRLSNVPSRYPVYRVGSQSRSVIPDTSENFLNLVRTWTGPLKQARVMEVDKHNSARKILLVYYGRVGRLSHFDPMHWKWKNDMGFTMYNAKIGRELLSDKFTLQKPIVEKWRHEEPPLLQPSTRRGWAGRWASDSQEPPPGVTPFRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP23</accession>
    <name>A0A8T0HP23_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_VG111400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0572624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7249" checksum="B392E14412E7B9FB" modified="2022-10-12" version="1">MCACGTPVAAVYVDHAPGNIRLSECAQCGYAADEYVECEIMVLHCTSMCRCARDQSEGRALGANACCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQF8</accession>
    <name>A0A8T0HQF8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG141500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8607" checksum="5F0AEEF0A98C86EE" modified="2022-10-12" version="1">MASPSEAPRHRPNELQSIISLSTYAVGLNSITGSSKLLRIPLKHTEDLRRETMRGRRGVGKERDGEGGSYKMKNRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQG0</accession>
    <name>A0A8T0HQG0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG153000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="11236" checksum="2955C3467FA16A36" modified="2022-10-12" version="1">MRSLTCGYGDCFNVETMRLLRRCSCCPFYLVSVLLPVSMLKVTEFVSRWQRIECPEKGGGRSSRKDFEIKKNRILPSCVSIIDSQYLSRSVMVPCGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR79</accession>
    <name>A0A8T0HR79_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG170300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="80" mass="10326" checksum="FDE2103EE476BA0B" modified="2022-10-12" version="1">MFVTLLCCLFFFFFFIFFFFFFFVYFIGMYLYLSVFFYLNFPLFFIFLYFSCLRTFHFPFFNYLLIFSFLFFLIFLIFCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR91</accession>
    <name>A0A8T0HR91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG179000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9195" checksum="69C641F14C067E7E" modified="2022-10-12" version="1">MWPSAAMKESLETTWVTTSRSILNRLTAQFPLEIACCKPFVSVSSLMGWQNLEQLANEGHKADSIPPVYARDERADAALAKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRI5</accession>
    <name>A0A8T0HRI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG187000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11438" checksum="DC15A3080300B2C0" modified="2022-10-12" version="1">MDQFLSVPCLGSVKLPISPSFSSLVVLCVHSMMSMMAFLCDCLRCVEALMMLSCGSAGLKYELMPVYIELQQLSHKNLSSCRFLTTKPHRVSEMLSCWHSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRZ1</accession>
    <name>A0A8T0HRZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG201400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="21602" checksum="29E5A76DDB9AFA72" modified="2022-10-12" version="1">MGFSTIVYNSDYGIRSGRINRFNGVSSWTEQSIREYELGFLGPRHECIEDCGCVACRRLHWLNHLDCKCPLGNWRWKSLSLEDAMKRKLLRCRCQPTIESYSPEECCPCLLLLTTQEGTVSANDSEEYVGSPYGDNATLFRLMNSEGESSDRLNRPLTEREIQSITAMAQRLQKEYEAMASAFPPLGVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS85</accession>
    <name>A0A8T0HS85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG211300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS85"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33977:SF1">
        <property type="entry name" value="ZINC ION BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="287" mass="32457" checksum="727CFF8AE5A96063" modified="2022-10-12" version="1">MPHANQDTNAAVESYHTNLKAILRTSRQKFGGRRVDWLIYHLLKDVLTHYWYAMQCKLYGFIKNGKAEGIVASAVIRDEEIPDEHVKISEEYDITYVASQTNFPTIWVISSPNSDWASCNCPLGMRGNICKDVVKVFCMINVDLHPVEIIRFGGSLRGTIQMGALTAGLQTFDGDCREVGTREKSQNVPKLEDPEEILDEINADLAEMGTTARENLNSRSQFLAMIRELKGKMATLRVKSEKGLLHPLSQPSFKVTTRSSNLRRFKACSETGRKKANTRGKRRRSQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1D7</accession>
    <name>A0A8T0I1D7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G104900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1D7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="95" mass="10688" checksum="289A9384406CE0DF" modified="2022-10-12" version="1" fragment="single">MLPSSLRPVLTLVMMESFLGRLYCNIDVFRGCSRNRTLSSITLQPVRSTSPASTRKPFQAPRRRLLTDRFPQTKLSSPTLPTISATQLNKPTPQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1M9</accession>
    <name>A0A8T0I1M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SigF-like NTF2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G111900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057514">
        <property type="entry name" value="NTF2_SigF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393">
        <property type="entry name" value="CHROMOSOME 1, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35393:SF1">
        <property type="entry name" value="SNOAL-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24840">
        <property type="entry name" value="NTF2_SigF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SigF-like NTF2-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="176" mass="20615" checksum="F1E6B0CA400806DF" modified="2022-10-12" version="1">MEDPVREVEGVLRALVDKPTLRRQKETLEKYCTEDVEFYHLYINLNTGLKALIAVYQGAELFLNYSGVDFHKIVYDAHANALAIRMTVYIRPWLLLWRTTPLRFHVLLELEDAIVNGRKVKKIKVQRDYFIRSPILQLIPFLGEIYDSDTLRFFLGNTLALMNKFILWLVNLLSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I378</accession>
    <name>A0A8T0I378_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G153900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I378"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6924" checksum="F1879255F7158777" modified="2022-10-12" version="1">MNSFSMLFVDNSSNGRRAQQRTDFSALMRILLVLTRWLAYPYSTTLQESPHSKLCTARVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I457</accession>
    <name>A0A8T0I457_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">adenylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G175400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I457"/>
    <dbReference type="OrthoDB" id="442176at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000315">
        <property type="entry name" value="Adenylate kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0577709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="227" mass="25518" checksum="037B3A3D8EF92701" modified="2022-10-12" version="1">MGKTKICHHNHHHPKSRPIIFVLGGPGSGKGTQCDRIVRDFGYLHLSAGDLLRDEVKKGTEIGRECEQLMKDGKLVPVDVTLRLIKKAMKEGKMNNAKGFLVDGFPRAVDQAEMFEKKVGRPRLVLFLECPREEMEKRLLKRGETSGRSDDNMATILKRFDTFLRESVPVVKFYDNLQPGILVKVSSVPPPDDVYKEIYCAILSFKGESDDDPMCAALHTDSCDKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4F6</accession>
    <name>A0A8T0I4F6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
            <ecNumber evidence="4">3.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_4G023700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the LpxC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.108" evidence="4"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4F6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001289">
        <property type="term" value="P:lipid X metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="entry name" value="lpxc deacetylase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="entry name" value="lpxc deacetylase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694:SF1">
        <property type="entry name" value="UDP-3-O-ACYL-N-ACETYLGLUCOSAMINE DEACETYLASE 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0578450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="347" mass="37036" checksum="41E0F6D9B4716105" modified="2022-10-12" version="1">MLRAAAMPHLSAMSCLRGSWNGWRSGTGTLVKLQAARRGITAALHVCQTAQLQQTIATPVTRVGVGLHSGERATVKLMPAGAGEGRYFVKLRQNATILPALVKNVTDTRLSTCLGRDGCAVHTVEHLMSALEGLGVDNCRIEIEGGDEVPLLDGSAREWVEAIEESGLSVAIDSSTGAQSARNSFVVVAPISVTHGDSFVAAFPSPFTRLTYGIDFPQVPAIGSRWFTWTPTGSSSYKDEVAPARTFGIAEQIEELRAAGLIKGGSLENALVCSMDKGWLNPPLRFEDEPCRHKLLDLIGDLALCASPGHAGLPVAHIVAFKASHALHVKFGAALLRHRMKCEEVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4R8</accession>
    <name>A0A8T0I4R8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G034400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4R8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035739479" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5951" checksum="E25B6E06DDA775AF" modified="2022-10-12" version="1">MFLFTSLLLVFSQFRLISVHHTSCYHPHIFVNINEPVLFRASSSLNDINFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I587</accession>
    <name>A0A8T0I587_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G009700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I587"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7186" checksum="027C937E3FF6B5E4" modified="2022-10-12" version="1">MLSVWVNHPKDLAVNPAAASLDDPAMAGSLGDPLSSVHTVMAPMAFVVAWRTVSSTSNAACPSGSSTDWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8M8</accession>
    <name>A0A8T0I8M8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Heat shock 70 kDa protein 12A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G096300</name>
        <name evidence="4" type="ORF">KC19_4G097100</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8M8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10229">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187">
        <property type="entry name" value="ALPHA KINASE/ELONGATION FACTOR 2 KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14187:SF5">
        <property type="entry name" value="HEAT SHOCK 70 KDA PROTEIN 12A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="683" mass="75911" checksum="8B42CADB67807655" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8N0</accession>
    <name>A0A8T0I8N0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G125100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8N0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="344"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="358" mass="39783" checksum="C339A78FBE4A96D1" modified="2022-10-12" version="1">MASATERAAIGAEEARMEGKGPVGRAGDAAKAAATGRVDNNRGVGPFNDGLHNDGLHHDGLHNDGLHHDGLHHDGLHHNGLHHDGTHLGPNGTQVGDRGLLKDHHHHNHGGLLGHTEEEMARLRNRTSITHEGEAYCPNPNIRDLPKEFETRVQVIQRYPEMKTVEKTDFVKEVHHEERTIIVPKTRIIHDEVERIDRVPVVRQVPKTRIEIVYRVVEEEREVTDMVPEVDYIDVPRIEMVPRVITEDVEERVTVPVVREVPVTRMVEVPTGNYCEAPVGEFVNPGDFNLLTHKHGHHGGTLGGLLNRTKSSSSSSSSSSSDDERRVREGNVTHHADGTISPGAHKKKPGLLQRIIHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I926</accession>
    <name>A0A8T0I926_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G083000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I926"/>
    <dbReference type="OrthoDB" id="370932at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1050.10">
        <property type="entry name" value="At2g23090-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039713">
        <property type="entry name" value="At2g23090-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039438">
        <property type="entry name" value="At2g23090-like_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007513">
        <property type="entry name" value="SERF-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026939">
        <property type="entry name" value="ZNF706/At2g23090_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788">
        <property type="entry name" value="OS07G0114300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33788:SF1">
        <property type="entry name" value="ZINC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04419">
        <property type="entry name" value="SERF-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12907">
        <property type="entry name" value="zf-met2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118359">
        <property type="entry name" value="Expressed protein At2g23090/F21P24.15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Small EDRK-rich factor-like N-terminal" evidence="2">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="At2g23090-like zinc-binding" evidence="3">
        <location>
            <begin position="39"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0579221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="8480" checksum="938F1AFC3D89261D" modified="2022-10-12" version="1">MGGGNGQKAKMARERNAEKLKGAGKGSQLDSNKKAMNIQCKVCMQTFMCTSNEAKCREHAEAKHPKVDVTACFPHLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9T0</accession>
    <name>A0A8T0I9T0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G084700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9T0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="14738" checksum="ECC60BFCC485D181" modified="2022-10-12" version="1" fragment="single">CRRSCLNPHSAIGETNLKGDSSTSPLEACTGPGAGLVQRHLMLPAVANLDDENLERVCKVPAHVHQTLQTQAYGWELFTDHARLHTRKTLLVALARHSTQRRSMHGLNLTPNSPCRRSKQARRALKSLKSMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGQ0</accession>
    <name>A0A8T0IGQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G095200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00183">
        <property type="entry name" value="TFIIS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.10">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003617">
        <property type="entry name" value="TFIIS/CRSP70_N_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035441">
        <property type="entry name" value="TFIIS/LEDGF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017923">
        <property type="entry name" value="TFIIS_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46548">
        <property type="entry name" value="BAH AND TFIIS DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46548:SF1">
        <property type="entry name" value="BAH AND TFIIS DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08711">
        <property type="entry name" value="Med26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00509">
        <property type="entry name" value="TFS2N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47676">
        <property type="entry name" value="Conserved domain common to transcription factors TFIIS, elongin A, CRSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51319">
        <property type="entry name" value="TFIIS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BAH" evidence="5">
        <location>
            <begin position="38"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="TFIIS N-terminal" evidence="6">
        <location>
            <begin position="323"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="177"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="438"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="718"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="843"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="911"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="963"/>
            <end position="1149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1204"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1311"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1370"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1623"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="220"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="451"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="519"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="566"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="643"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="786"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="914"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="994"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1070"/>
            <end position="1114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1658"/>
            <end position="1667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0582910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1704" mass="179128" checksum="6C9C91D7B4228EC6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGQ9</accession>
    <name>A0A8T0IGQ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nucleolar GTP-binding protein 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G034900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biogenesis of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
            <location evidence="1 6">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGQ9"/>
    <dbReference type="OrthoDB" id="415015at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01897">
        <property type="entry name" value="NOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1190:FF:000001">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000496">
        <property type="entry name" value="Nucleolar GTP-binding protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024926">
        <property type="entry name" value="NOG1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041623">
        <property type="entry name" value="NOG1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010674">
        <property type="entry name" value="NOG1_Rossman_fold_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012973">
        <property type="entry name" value="NOG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45759">
        <property type="entry name" value="NUCLEOLAR GTP-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06858">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17835">
        <property type="entry name" value="NOG1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08155">
        <property type="entry name" value="NOGCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038919">
        <property type="entry name" value="NOG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="OBG-type G" evidence="8">
        <location>
            <begin position="169"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="474"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="519"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="485"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="597"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="609"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="635"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR038919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="673" mass="76545" checksum="5F9E0EFC7BEDF391" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKA8</accession>
    <name>A0A8T0IKA8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidinol-phosphatase</fullName>
            <ecNumber evidence="4">3.1.3.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Histidinol-phosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_3G123900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-histidinol phosphate + H2O = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="4"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKA8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:L-histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01641">
        <property type="entry name" value="Bacterial_IMPase_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.540.10:FF:000021">
        <property type="entry name" value="Inositol monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.80:FF:000013">
        <property type="entry name" value="Inositol monophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.540.10">
        <property type="entry name" value="Fructose-1,6-Bisphosphatase, subunit A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011809">
        <property type="entry name" value="His_9_proposed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051090">
        <property type="entry name" value="Inositol_monoP_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02067">
        <property type="entry name" value="his_9_HisN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200:SF6">
        <property type="entry name" value="3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43200">
        <property type="entry name" value="PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56655">
        <property type="entry name" value="Carbohydrate phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="12">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600760-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0583287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="372" mass="40177" checksum="9C0CB8543C455DE2" modified="2022-10-12" version="1">MNSAAKAVGRKVLTVFAGRGGVRAAGELASGARASSSLADITVQNLESSYTTDVLDRARVLPFRHRQARFSTSFAGEVPKLTHVTTRSEHSAALAVEDDKGYESSSSMEDFVEVGHKLADAARSIILKYFRSGFTIIDKEDLSPVTIADRETEAAMCSILSQYFPDHAIFGEEGGLTMPEGGSDYVWVLDPIDGTKSFITGKPVFGTLISLLYKGTPVLGIIDQPVLGERWVGVQGQGTTLNGRRVRTRSSTALLKDAYLYTTSPHMFSGETEEAFVRVRNEVKIPLYGCDCYAYGLLASGHADLVIEHGLKPYDYLALVPVVEGAGGKITNWSGESLKWLPEVGEHSIGVLAAGTRSLHKAALDLVEERNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL63</accession>
    <name>A0A8T0IL63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G177100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="12533" checksum="F608000DBD27E3F7" modified="2022-10-12" version="1">MFHRKHNQTAEYANVPAGAVGGTSNYPAGQSAGYGYEAGRDVNVKSGYGNTGNAVPQQSGGYGGGYVQHQQTPVSYGPAGQPVEAYPRKRSNRAANWCAAAFVACWACTWPCHGPCCCGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILE6</accession>
    <name>A0A8T0ILE6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G157300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="15363" checksum="18256240FE416015" modified="2022-10-12" version="1">MSSTLWSSVYQGISNFLSGGPNSQSSVILPSNLPWPGCFRVEFIRRRNTRAEQRRVYDFYFGDPNRTVGPLELFLRLVACPEWIQGELELRGPHFDDLISESFVFLPSGSYLSRISNRWAGLFERALSLSHNFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILQ1</accession>
    <name>A0A8T0ILQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein arginine methyltransferase NDUFAF7</fullName>
            <ecNumber evidence="7">2.1.1.320</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G142300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>L-arginyl-[protein] + 2 S-adenosyl-L-methionine = N(omega),N(omega)'-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-homocysteine + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:48108"/>
            <dbReference type="Rhea" id="RHEA-COMP:10532"/>
            <dbReference type="Rhea" id="RHEA-COMP:11992"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29965"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:88221"/>
            <dbReference type="EC" id="2.1.1.320"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NDUFAF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.320" evidence="7"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035243">
        <property type="term" value="F:protein-arginine omega-N symmetric methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003788">
        <property type="entry name" value="NDUFAF7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12049:SF7">
        <property type="entry name" value="PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02636">
        <property type="entry name" value="Methyltransf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="37"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="37"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0583508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="482" mass="52128" checksum="2E9A9CCD510492E7" modified="2022-10-12" version="1">MAGPHLLLRSAHALQRSCRFLSSSALVFSTRPPGAHPLPGADAAADADQPAPVDRSGLSNAPGAAKETAMAKHIKALIRSRGGPITVAEYMEEVLTNPSAAFHLNRDVFGTHGDFVTLPEISQMFGEMVGVWTMCLWHQMGQPEAVNLIELGPCRGMLMADLLRGTAKFKDFSQKVSVHMVECSPALRKIQRETLICVPKVGEEGKLAEDSRSPVPTNEQISQISGAPIFWHLDIEQVPRGVATIIIAHEFFNALPVHQFQKTPRGWCEKLVDVAEDSSQGLKFVLSPGPTAASEEFLTRRMRWASLDEKAEVEHVEVCPRAMKVTAEIAKRVGEDGGGALIVDYGELEKVVSDSLQAIKKHQFVNVLDSPGDADLSAYVDFSALKHVVEESAAGASAYGPITQSELLGALGINFRLEALVRNATDKEAEALNHGYWRLVGVGPSPWLDSFDDPNSLPPGMGAEYKALTIVNDNCGVPIGFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILX2</accession>
    <name>A0A8T0ILX2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G171800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILX2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035802288" evidence="3">
        <location>
            <begin position="25"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="24004" checksum="F7855861BEB762AA" modified="2022-10-12" version="1">MASTGGAFFLLLVICSSCVLSVAASIDGRPRPANFPDQPTTTYDQTPALSDANGLAVDCTWYGFANELYDPATTASCLTVLRLALTNATVNPPAQMKPYIYYTLKRLVDPTNNQSYCYQGCFNLDGFLAPTPGVVGAAPPVGMDAPPPATFGVPPSSFSPVPSATPDASPPVESPAPLGAAVPPMGVAPASGPSSGLGASPPAPPILIPNSGAFLQPGALLSFIVAFVAVFVNFAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM71</accession>
    <name>A0A8T0IM71_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Suppressor of white apricot N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G241500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040397">
        <property type="entry name" value="SWAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019147">
        <property type="entry name" value="SWAP_N_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161:SF4">
        <property type="entry name" value="CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13161">
        <property type="entry name" value="SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09750">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01141">
        <property type="entry name" value="DRY_EERY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Suppressor of white apricot N-terminal" evidence="4">
        <location>
            <begin position="39"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="175"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="196"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="252" mass="28530" checksum="B2879F382D21298E" modified="2022-10-12" version="1">MWHEARRSEKKVHEIMDAARRRAQKRAIFLAKRRVDPQQTLRIVGTRCRVHHDATVYQATEDQQGLIPWNGKEDNLIDRFDGRALLDMIREYSSATHQHLLPERTEEEDELEVMVNFQRYRDLIKQRRRGLSDKQGLEDVEQELEARSTAPFPGDKQRAAVAKPTYGQVGFAYEGAGGSSGGAAKEEALGAGLGESDSDEEAVEEEEGSSSEDSEDELIESIGQDYGVQRFNSLLSLDRKLKEEEGRAKELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMM1</accession>
    <name>A0A8T0IMM1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G197900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009943">
        <property type="entry name" value="DUF1475"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36318">
        <property type="entry name" value="OS06G0581300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36318:SF3">
        <property type="entry name" value="OS06G0581300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07343">
        <property type="entry name" value="DUF1475"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="74" mass="8672" checksum="7A614185AF444F20" modified="2022-10-12" version="1">MQVWVCYKESSLASRLLWVVLLICFGSITTCWYVAIELFKMSPEDPMYYVLLRDRTMRWTGSSVLDNGHTPSIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ14</accession>
    <name>A0A8T0IQ14_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G258100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ14"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000056">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="532" mass="58732" checksum="5AF8D9389AE857A2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRC7</accession>
    <name>A0A8T0IRC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G265400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRC7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035943417" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="10261" checksum="35190C0DD4148657" modified="2022-10-12" version="1">MTYYRCFCWWLCPVSVCCSLQAVSHLPTCFNRIFLQYFLVVYKRPVQNLHHLFRGWLIVLQRFLSIIPCDGLVILISNLFSDAWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISM9</accession>
    <name>A0A8T0ISM9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G060900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051553">
        <property type="entry name" value="Ran_GTPase-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45982:SF1">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13540">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="435" mass="46771" checksum="7B2C8A33C07E805E" modified="2022-10-12" version="1">MEPKRPPAALAAVRYASASNAENLEYYGWGEVVQCYRTRCSELAAMKLKPTASPIVHLAASQHHLAALTAAGQVIVWRNQHGNIRTRCDGWEFISDLENKGVVLIDIAGPDIDRRSAGYGSEQEDQVPDPFYLDAITSNGEDYLLQGSCPQEHVRTQRLRDNPKIKGLRSTLSQINPGSLKNLGLVVQASVGTIEAPDETPFVGYITDANQVFIRSATKEFMDEVNLVTGYTGMPLKIQCGGVYHAVLLTDDGRAWTWGRGYYPLPTSQVSSSKSKNQSPFSTCHLALGTLVGRKVVDVGCYGEDFVALTSDGCVHHWTHGVANPAADIYNFPSTPAAGQGPSVAPGDKITRVSIGVGVCAGVTEQGKVHTWRALWRGALVGLRGPGTPLGREYSGQQTVVPFLGTKFAIQVICVAGSLIVVAEKKAKGKLGPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITE4</accession>
    <name>A0A8T0ITE4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G133500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITE4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13934" checksum="6A70719F34B9E48E" modified="2022-10-12" version="1">MSLSSLIQVPGGTTQQAEPVRYTIDRSISPSSVSNRHRKCTTKLHLQILRRFLKTTHSVPENNPIQCTPANLITQTLNPRRSSLSLLHTHTHTHTPSQNPKDSKLLELDRLFVSHCFFAKVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITG3</accession>
    <name>A0A8T0ITG3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">adenylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G133800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITG3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:AMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="NUCLEOTIDE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00406">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0587000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="17243" checksum="9D371D5419C070FB" modified="2022-10-12" version="1">MIQNMMKDGKIVPGEVTVKLLQKAMEESDNDKFLIDGFPRNLDNLKCFETVTDIEPQFILFFDCSEEVMERRLLGRNQGRVDDNIETIRERFKVLVESSVPVVQFYEEAGKVHKIDATRTVDEVFSSIEPLFQQSNPTSIQPCQQHFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUH7</accession>
    <name>A0A8T0IUH7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G118100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035783887" description="Secreted protein" evidence="1">
        <location>
            <begin position="40"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14472" checksum="B40948E6C4DC36CC" modified="2022-10-12" version="1">MITEARESGGRGHCQKPGVALQLVCCSSLLLLQLRLARCNHRCERSHRLAGVWTLPGTLAAPPLDLITLSYSALPVGASREFSCSQSLVFSRFGQRLLFLLLHPQLWRPSYWFFIWVSEVLDGERGYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVA6</accession>
    <name>A0A8T0IVA6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G080700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVA6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="102"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="15743" checksum="8D8B190ECF193814" modified="2022-10-12" version="1">MREAVVKGKDMGPRFAGTTDLVRVFNRALELLNSTTPESDQELLELVKKSKREMEKESSVPPTKKSRRGPSEVGDFQALGHRPNIATLTGDHGSGQSGSGSEGTPTQSTSGTSANVAHAQVRPIQMIRNPGRGGGRGEKHKRKINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVN4</accession>
    <name>A0A8T0IVN4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G148900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="173" mass="18468" checksum="BF2E0077105E645E" modified="2022-10-12" version="1">MSCTIFNIPKSYRGSFGTSKKLGYSLEAILSCNPCINLGDRIDYITGNGREYLNLYVHFCDPGCRSGDNIRAGGCVEEGRVSLRRVGRVLLGSEGGHSVVKADRPCEGACASPSGLRHILRLRRGGGAHLHFGVSHRWTCGVQGVAQGAAKGASEGVPEDFHTCGARMDNSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVN9</accession>
    <name>A0A8T0IVN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G114000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVN9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013">
        <property type="entry name" value="THAUMATIN FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31013:SF2">
        <property type="entry name" value="THAUMATIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035752176" description="Thaumatin-like protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="31"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="134"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="215" mass="22151" checksum="A995372BEBF27559" modified="2022-10-12" version="1">MANVQLAAVVLSLLAITSCVCATKINVRNQCSFAVTACDQGQGSGVTCYALQNGGQQQKDVGASWPGGLFWGFPSGSGDAGQGNAAKPQANLAEFTIGSNGQDYYDLSNVNAYNLPLMINPTNTNGDTISGSHCGTLSCTINNLNSFCQAPNRLTGTPGNGCYNVDGPGNNPTAGTQAFKNACPSSYAYSKDDTGNPPVVYACKAGSDYEVVFCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWN4</accession>
    <name>A0A8T0IWN4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G115200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWN4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="324"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="446" mass="49930" checksum="C377BBFEE73D4A0E" modified="2022-10-12" version="1">MKTSPRTSRCDSAYSGQIPKGLGAAILRNPDAVFGLVKRRKSKRKSVKASIRKHQSEIIPIVDPNARKTKSASQARRRSSAAAPRRISTSAGGSGSGGAAATKRRSLNAPIGGMGEIRTNEVQDEDRPSKWGSPRGSIEAMAMSGTLDLKDKVTPPFPTGKRDVPHWPFVGGVPQTRGPAGRFSLMQIHFSDVYGEKRPKKNKYSLRLFLQDCHRKEREAKLAEFGDKDHKLWQMGLRGDQKMPGIVGEGNEYYRKKFEKWARNIIDREKKLLSHTEVEGSGETSFMPGVATSEMMKLKKGRGKDGRPQYIPPGHKETSSIIDIGCLKAGDFFGERGLMTASKRAASIVAVTTVETLVLTKWDFHRHCDRQVLKIFKGIRRVVNEVFEGKARRFHVGPRKIRVLPKPNRNKHELPVKEWLFKSQPTVLPSFPNQDPFALMRLTMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZ95</accession>
    <name>A0A8T0IZ95_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G232400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZ95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="15913" checksum="B816E8643A7E4996" modified="2022-10-12" version="1">MPDPGPHQQPPSCDVAEQVDAPDEVAALGQNPHDASYILDPAPASYTLDDSSMLDEDHAPSENLEYNWWEVLGELIEDNPNRALGNESSDLFPLALSTDRFGTMNSDPGPDNFDCDEETSDIDKELAAEADRLIASADGLHELFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZJ9</accession>
    <name>A0A8T0IZJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AP-2 complex subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G240200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type and beta-type subunits), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000020">
        <property type="entry name" value="AP-2 complex subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3 8" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="11">
        <location>
            <begin position="771"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="623"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="715"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="7"/>
            <end position="8"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="53"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate)</name>
            <dbReference type="ChEBI" id="CHEBI:57836"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00054328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR037091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR037091-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0588402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1031" mass="113947" checksum="0E22F49210216763" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZK5</accession>
    <name>A0A8T0IZK5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G191700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZK5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12964" checksum="3716F027AFEF70B7" modified="2022-10-12" version="1">MRGSTFQTRTQVDRGTDSSKDTSCTITTSKPVQALSTHRQRLSKNRTSIVNSMPSPRWAKCSHKWHIHQAPLILFGTSKWAWNWPRLLRELDVESCQLEEHGGLGTTKICKPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0J2</accession>
    <name>A0A8T0J0J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DIS3-like exonuclease 2</fullName>
            <ecNumber evidence="5">3.1.13.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G292800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
            <location evidence="5">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNR ribonuclease family. DIS3L2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000956">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990074">
        <property type="term" value="P:polyuridylation-dependent mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.690:FF:000007">
        <property type="entry name" value="DIS3-like exonuclease 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03045">
        <property type="entry name" value="DIS3L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028591">
        <property type="entry name" value="DIS3L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF9">
        <property type="entry name" value="DIS3-LIKE EXONUCLEASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNB" evidence="7">
        <location>
            <begin position="948"/>
            <end position="1309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="113"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="211"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="255"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="408"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="596"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="739"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="813"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="121"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="429"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="960"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="969"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="5">
        <location>
            <position position="968"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0589125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1587" mass="172963" checksum="8E059807F5856346" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1F6</accession>
    <name>A0A8T0J1F6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G273900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1F6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="284" mass="32058" checksum="04D3145C8624BB96" modified="2022-10-12" version="1">MPSLHHSDFPWNPDGGFEVDAGSGSRCKKRKLGNHRNRGVTGIASSRSDYMGVRNRGFTVEIKKWFEGLDFYRNDVKMSEKEAALVHDLARLYVDITWDRLNIQALESRMQEEDPALAKFNRTLQIGKDFLIGFVEMHPLMEVAGNSKERADSMKDDIIALAPVAYECLKEKITSEHSIRAVRQKKEVDDVSSFAQLKRENEDLKATVSAQDAEITSLKGALNAAHEKGRYMETELYAAKQAARAARMTPCEPAGVAERERFPQNESNPASETWKDCIDWSTNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J240</accession>
    <name>A0A8T0J240_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G061200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J240"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="204" mass="23266" checksum="E0668E75C917D30F" modified="2022-10-12" version="1">MECRKVQEQASSDEYEVHVVVVGSSSSYQSLRFALLASSWLPLRLGILVWSVVHLLLVVVSILACVIFMLCSNPCFIYMLCFIILYYFFALPLMFFINALRDIVVLIIDTLRFIFVTIRVIVSGEATPGTATKVAYERIGGIRLFRRVIAFMIANHSVEELCRDPNERGEAQEPGMGPAEPRNTLEWQIKRWCKEIVPHYDVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2Z5</accession>
    <name>A0A8T0J2Z5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G006500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2Z5"/>
    <dbReference type="OrthoDB" id="2019572at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF99">
        <property type="entry name" value="GLYOXAL OR GALACTOSE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035717933" description="Galactose oxidase" evidence="2">
        <location>
            <begin position="26"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="41"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="426"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="527" mass="55516" checksum="D3529F2ACEB32D73" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J350</accession>
    <name>A0A8T0J350_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiaminase-2/PQQC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G028600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J350"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19368">
        <property type="entry name" value="TenA_C_AtTH2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050967">
        <property type="entry name" value="Thiamine_Salvage_TenA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198">
        <property type="entry name" value="BIFUNCTIONAL TH2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198:SF2">
        <property type="entry name" value="SI:CH1073-67J19.1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035948696" description="Thiaminase-2/PQQC domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="2">
        <location>
            <begin position="90"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="575" mass="64759" checksum="FBF5B3C22AE1F512" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3I7</accession>
    <name>A0A8T0J3I7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G103800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035907874" description="Secreted protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="83" mass="9572" checksum="307CF4CA9A3DC64D" modified="2022-10-12" version="1">MPARAYATWCCLLLSHFIVPFPVIVMGELCVQTQYSIVRSVVGCSCRKDICQIDDGVRLFRWCTANYFLTWKNHTHSVVVSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4M4</accession>
    <name>A0A8T0J4M4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G131600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 40S subunit of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Part of the 40S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4M4"/>
    <dbReference type="OrthoDB" id="2013099at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000008">
        <property type="entry name" value="Ubiquitin-40S ribosomal protein S27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_eS31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038582">
        <property type="entry name" value="Ribosomal_eS31_euk-type_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="11">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00035123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0590854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="155" mass="17715" checksum="860EA0F8A121DC5A" modified="2022-10-12" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKLKHKKKKVKLAVLQFYKVDDSGKVQRLRKECPNPDCGAGTFMANHFDRHYCGKCGLTYVYQKAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5B1</accession>
    <name>A0A8T0J5B1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G083000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5B1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="10678" checksum="7158D86D73C28304" modified="2022-10-12" version="1">MMLFDRVHAVSRSWKGTVQRRRRMGESTGGGGAGRAFSCCPSGLNSERKQVGCGFGNSVTWEISGGGLLNPGKNTAFVFKGGIAPGVVQGFTPWRLLQFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5B3</accession>
    <name>A0A8T0J5B3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G150400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5B3"/>
    <dbReference type="OrthoDB" id="541154at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="78"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="266" mass="28967" checksum="17AD86665D0329AF" modified="2022-10-12" version="1">MVDKAIKEPKDFKSPDMKHAQGGSSQAFVLGSSQSQGSQGGSEGREGKERSPHQRLHGMRTRSSGACDFLETPAERLHLEPHHFAEGWSGRIVRGTYEGQRIVVKLAPTGSDRAEALLTEVVAYHKLKEFWGKYVPKLVSYGTTAGGKVVYIATEEIDGREIGMGTLSPQVVKEIFDALAVVHGSGILHGDIRPSNILVVKGRQAGVRLLDFGFACPITSSEDCMRERDQLECLLNEFTCSDVGVTRQSQLGEIVAVCDSQGRRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8C7</accession>
    <name>A0A8T0J8C7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G200200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8C7"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16461">
        <property type="entry name" value="RING-H2_EL5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044289">
        <property type="entry name" value="ATL67-70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46592">
        <property type="entry name" value="RING-H2 FINGER PROTEIN ATL67"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46592:SF14">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="113"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="188" mass="19981" checksum="7C85471BD3C798D6" modified="2022-10-12" version="1">MDSSNTTTMQVSLSKVGLGYGIAIAVGILVLISTIMLASYVCVRVHQTSSGSSHSGTNSTVPPHHSGRGDDGSGTGPFGEWSTGGLDQITVESYPKVVYSSSQPLPHLQDTSCSICLGDYKDGDMLRMLPECRHMFHAPCIDAWLRLHASCPICRTSPLPSPLATPISTPLSELIPLARHPLGIRSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8Q5</accession>
    <name>A0A8T0J8Q5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_1G161900</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15 23">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14 23">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8Q5"/>
    <dbReference type="OrthoDB" id="543442at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000108">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase S.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000178">
        <property type="entry name" value="serine/threonine-protein kinase PBS1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 19" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="19">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035869704" description="Protein kinase domain-containing protein" evidence="19">
        <location>
            <begin position="24"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="384"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="283"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="689"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="288"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="17">
        <location>
            <begin position="705"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0591263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="728" mass="80015" checksum="E66E467EB8FE128E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J910</accession>
    <name>A0A8T0J910_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Reticulon-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G216800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Endoplasmic reticulum membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J910"/>
    <dbReference type="OrthoDB" id="567788at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009617">
        <property type="term" value="P:response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003388">
        <property type="entry name" value="Reticulon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045064">
        <property type="entry name" value="Reticulon-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10994">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10994:SF193">
        <property type="entry name" value="RETICULON-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02453">
        <property type="entry name" value="Reticulon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50845">
        <property type="entry name" value="RETICULON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Reticulon" evidence="7">
        <location>
            <begin position="55"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="241" mass="26670" checksum="6CF45D47C2477D25" modified="2022-10-12" version="1">MSEQSDVTQNVPDPVMETVNKMPASQTAPVSQYGPGNRFLTKDKTVHQILGGGRAADSALWRDKYLSAGTLGGSTLAWFLLEKSGYTFMTLLCNILMFVVVILFVWSNVAALLHRPGPPVPELSLSEDFVLSTASVFRYDVNKALAIARDVALGKDFKLFLLVIAFLYVVSTVTSWFNFLTCVWIGIVLLHIVPFVYDKYEDVIDHHAKKAADVASTHYKNVDAAVLSKIPRAPAKQKKMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9C9</accession>
    <name>A0A8T0J9C9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Protein-S-isoprenylcysteine O-methyltransferase</fullName>
            <ecNumber evidence="3 10">2.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G258400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12125"/>
            <dbReference type="Rhea" id="RHEA-COMP:12126"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90510"/>
            <dbReference type="ChEBI" id="CHEBI:90511"/>
            <dbReference type="EC" id="2.1.1.100"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Divalent metal cations. Probably Zn(2+).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Endoplasmic reticulum membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.100" evidence="3 10"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9C9"/>
    <dbReference type="OrthoDB" id="422086at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025770">
        <property type="entry name" value="PPMT_MeTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714">
        <property type="entry name" value="PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12714:SF9">
        <property type="entry name" value="PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51564">
        <property type="entry name" value="SAM_ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0592510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="243" mass="27767" checksum="A122E369C2FF8D7A" modified="2022-10-12" version="1">MGEDSCRSTWKEIIYSLGVSHLKWVRERAADLRHVRVLESAAVSVAGTASMGFTPWEQLWVMLGAVVFFHTSEFLLALAHHGRRRVNAASTLISGPYLVALAFSMVEHALESRFAPRLKEQAFVSYTGLAMVVVGEGLRKLAVVTANKSFTHDIKVDKRQEHKLITHGIYRFFRHPSYLGFFIWSIGTQVLLVNPVCTVGYAIVTWRFFDHRIPYEEYFLRRFFGQDYVDYANRVPSGMPFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAP3</accession>
    <name>A0A8T0JAP3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G218800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ADIP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAP3"/>
    <dbReference type="OrthoDB" id="312015at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021622">
        <property type="entry name" value="Afadin/alpha-actinin-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057">
        <property type="entry name" value="AFADIN/ALPHA-ACTININ-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47057:SF1">
        <property type="entry name" value="AFADIN_ALPHA-ACTININ-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11559">
        <property type="entry name" value="ADIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="82"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="357"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="377"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0592023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="48907" checksum="A77861A1FEDD0D0F" modified="2022-10-12" version="1">MGMSDGDAGYMGAYDPSYTSGDDTFADIHNLDHCIKYLNQSLVTFGFPSGLNLYSSEPGSIVRTCNCIYAMIQQRQRDIEYRETANETRQRLMSDMSRLEAKVERLTDQLASKERELQAITSKEQKAAATSRAQIERLQHEKDEFQRMVISTQQVKIQQMHELKKKEKDYIKLQERLNQVLMEKKKESKTGIEIMNLLQKEGRQRGTWNTKKADGDFYKMIVDAYETKKQELVAENSDLRALLRSMQGDMRDFLNTPSGLMRPGTGASSHELEPPPTPLGGRTDVFDLPFHMARDQIEHSLRAKMSTIKERMTQLQESQIGLNAGRETSEREQALEAQLVEARSIISEQASLMNKQTSDDDSRNVSAERVDSEDRASTAQDTNSGEHGNIIAGSNDPSSVGDDYILHRKTVPNGGLGSLRPHRVPLVPTGYHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JBC6</accession>
    <name>A0A8T0JBC6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G240000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JBC6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052374">
        <property type="entry name" value="SERAC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48182:SF2">
        <property type="entry name" value="PROTEIN SERAC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="7">
        <location>
            <begin position="68"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0592293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="340" mass="38289" checksum="C8549A5BA06934F7" modified="2022-10-12" version="1">MDSWFSWMLGTVVVLWLTRWFLRQIGIGFSGLRTAPEDPKSPPPLGIKQLSDAVYLLHEPEGTPEIDIVFIHGLQLSEYKDAYWKTWTVPVDGTGEEICWPQTWLSEEFPNARISSVSYDSSALRTESRGRGDVYVVGESLVAEMVEFGQIGQQRPVLFVCHSLGGLVIKEVVIQAYRQHHDEEKYKNFLNNIRGFFFYATPHAGSKLADLAIALPLPSEKGPMLKHLEALGDTNSRLDSEFKTITDLPEFPNKWKFSVVAEKNATKMGNFSALVVSEASATYGGRRPYFANLDHFQVCKPTSKKASVFQKLTNFIVEDIMMSEKITTGAQVRENAKLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCC1</accession>
    <name>A0A8T0JCC1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G272500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SFH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.20">
        <property type="entry name" value="N-terminal domain of phosphatidylinositol transfer protein sec14p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="5">
        <location>
            <begin position="109"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="311"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0592682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="55452" checksum="8144B951A7C48891" modified="2022-10-12" version="1">MKAAFNKHREKHREKNLNKSAASLKNRAPSVKVEDYRELQEQRVVEKFRQKLIADESLPEHLDDYHTMLRFLKARKYDVHKAREMWKGMLQWRHEFGADTIETDFQFTELDSVRRYYPQGHHGIDKEGRPIYIELIGKVDPQKLMECTTLDRYLKYHVLEFERTINLKFAACSLATKRHVDSATTIIDVDGVTLHRMFIINAGTGFRLLWNTIRGFLDNKTAAKINVLGGNYQSKLLDIIEPSQLPVFLGGTCTCAEEGGCLMSDKGPWKDPTIVQAIKEGKLKTATKVVSIVDGKGEELACSNPKGKEAATTTEAGVSGSNVSTPEPAHELEDRFDAGSEHSTYNSDDPPEVEPSIGVLGNVVGFITSGVKLVFGVITFPFQLIVNIWSSLATLFSFPMRMPSDDHEPLQRRLTHLEQEVGKLKPLQEIIPKHIDQQPPADPTQKLSVLETELANTRKTLRSVLSKQEELYDLLERMKEFKCMQGKCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCH3</accession>
    <name>A0A8T0JCH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-terminal of Roc (COR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G299500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF1">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1388" mass="156613" checksum="274FFC6A02D420CB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G355</accession>
    <name>A0A8T0G355_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G028200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G355"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="14637" checksum="1843F2F6BBAAAC30" modified="2022-10-12" version="1">MAVQCRARQLMSRSEKRCACRRLPRGFRSPFATCASLARITPHAHAHAHAASPRCVQLQVTALVSMQNCSWESRSSSFSHCLSIILVALSEIDTLVSRERERVHRLSGCMVGGRGGVDRKRSGDQMKGLTGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3J8</accession>
    <name>A0A8T0G3J8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G014800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3J8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="209" mass="25355" checksum="3C0C2FFBEDDF7C0A" modified="2022-10-12" version="1">MTENKKTRPIVDFHIHRDEGRKQKAEYEEERLQGDLYNLKHNYRCVCYAPRRPLYSSLWPLKGFREPLEINNDPPKHDHKLQVITGRFNYFELEWKTIDILQYDFEKRIWFEVSSMPENYVKGHFQLQSWDSMHAYNYQDKIWIRRTDGVSQGAVYDCEKGTWELDWRFPIFPEGTAWFHSIAPYNVILNETPWVKYLPRCITHGMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5P8</accession>
    <name>A0A8T0G5P8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G104500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5P8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47381:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="122"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="379" mass="42084" checksum="A1A2010961E00403" modified="2022-10-12" version="1">MDTRVEGSTTALVWRNREGEEVRARLLDVLNSRRQLPVVPPEIFPAEHHNRPYLQQEASFVNPQVLALCPNAEGSCRQNTEELEEEDLVLRVEAGEQGNIPFLVIRPKLQNSTKVVLRRPVVICLHSTGNSKETMRPFMRAYASLGYVAVGMDARNHGDRGRSPHAYANALVAAWKTGQEMPFLFDTVWDLIKLIDYLTGRPDIDPQRIGMMGISLGGMHTWFAAAADPRIAAAVSLIGVQSFGWAIAHDQWHARVASIPQPFEAAAQDLGKNEVDTDTVAAVWQRLAPGLMDFLDSPHTVPAIAPRPLLVHNGEDDPRCPIEGLAEVVFRTVERYKEAGALEHFKFLAEEGLGHTVTAAMGDEAITWFNKHLRPETTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9K8</accession>
    <name>A0A8T0G9K8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G110000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9K8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="232"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="321" mass="36609" checksum="C01059BED1E9AFC0" modified="2022-10-12" version="1">MAEQEYMHPPSDAGNAGLYEKLEIYTRHVNERCIKAVSKVDSCKFNNKQCAYLASKLEGLVECSSSFLRAAQCEPCSSGIVEKWVETFKLMLILSKQIDDFVQSCCKEEWIQTAMTMTNTSEYVSSLGCNVEICKVACEGFLEERGGTENFTAVELQRFTWAELDKMYKKEVGIVKKKAEEDLVTLRDKATAELDGERDKVAKYLLRLLSKVQGRQIKDKKSLRASIFNWRVRRGRKLGKGATASVYEATWLGLRVAQKVFVGLDNPHFEEEVTNLAPLRHPNITSMFYCEQKNGNSSIIMELMDEDLHTYLHNRGICHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA78</accession>
    <name>A0A8T0GA78_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G182900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="296" mass="33328" checksum="5D8604B07E4BA428" modified="2022-10-12" version="1">MAEAIAIGIVVSLLQQAIPAAINKLKARFQQAKATQGETQELEDFLRCVQDCSIKYQNTSGGRVKTKTTTRSFAKSLENVQKTLDSWSSQNSGFFSRSSSERAEELRSLRRTLESAINVEILGMMVDQQRNIDLIMEKMGIRNSRTLERHPPPDVTKQPPKTQTNKERTKTTKSTNHARSNSTGRANTNPSKAPVLNRSRSKSVQRDPSHSSHRSEKRRTIDLWVSLDSEKQAKDVVNKLEGLQDVKKVFYDLVTKKVSVRLGEGSKLSTATLISEIQKAQSKDKVAPTLWLQHRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA88</accession>
    <name>A0A8T0GA88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G021100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA88"/>
    <dbReference type="OrthoDB" id="256303at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000146">
        <property type="entry name" value="protein RAE1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10971">
        <property type="entry name" value="MRNA EXPORT FACTOR AND BUB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="65"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="107"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="246"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0556041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="346" mass="38461" checksum="2884B2C5278F85EB" modified="2022-10-12" version="1">MANFGIAGAQPHNPNKSFEINSPPTDGISSLSFSPKANYLVATSWDNQVRCWEIQSNGSSDPKAAISHDQPVLCSAWKEDGSTVFSAGCDKQAKMWPILSGGQPVTVGMHDAPIKSISWIPEMNLLVTGSWDKTLKYWDLRQQTPAHTQQLPERCYALSVRHPLMVVATADRNIVVYNLQSPQTEFKRIQSPLKYQTRCVATFPGKEGFLVGSIEGRVAVQHIDEAQQSKNFTFKCHRDNNDIYAVNSIDFHPVHGTFATSGSDGAFNFWDKDSKQRLKAMQRCNQPIPCSTFNHDGTIFAYGVSYDWSKGAENHNPSQARNYILLHPTQDSEVKAKARVAASGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAH9</accession>
    <name>A0A8T0GAH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G171200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006502">
        <property type="entry name" value="PDDEXK-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01615">
        <property type="entry name" value="A_thal_3542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579:SF39">
        <property type="entry name" value="OS01G0973600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31579">
        <property type="entry name" value="OS03G0796600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04720">
        <property type="entry name" value="PDDEXK_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="373"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="43505" checksum="BE5FA2071C8D071A" modified="2022-10-12" version="1">MPGLRFPGPPTTVPNGSYSFFHDVQTPTGKDGTWDPVDINSVNFAAVEAVPFVPNKHKACRPPQFHAAWIKGKAGSATNAFNGLGCSLSTTGTMSAPVQGNGGNDSDDLAAMVLDFIESGSPAFLDASDSDNGPPNILQLRDTLEGLISSYGRMEAELVIAVRKLILAIDVDNDLICNSGGTARDCRCGCIKRLVVNQLRAAGYDAAVCKSKWEGSGRVLGGPVHMGEYEYIDVEVYCNQSVERLIVDVDFQDQFVLARATPNYLTSLKLLPTVFVGTTKRLEQILQIMAEAVKVSLKHNSMPLPPWRTLDFMKSKWLSPHERVADHKWGQSLPRGGSSSLILKGRLASTPETRQCDVQLRRIKDSLLSEVNHGSTVNVPGRGRTRHYSKPRAKRSMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCL1</accession>
    <name>A0A8T0GCL1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G080300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCL1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36077">
        <property type="entry name" value="BNAA02G07370D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36077:SF1">
        <property type="entry name" value="HOMEOBOX PROSPERO PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="18421" checksum="D32C83DBCD6EF2BA" modified="2022-10-12" version="1">MSYDAWKQVGKAMAGTYALMGLAWWWDETAPLGWWTLKPRTKEEREMAEQYERRVFPYPGDKEAVKEFIEQGGASGTTIGTKSDRQRAGDDRVSELQKEKFDREAQKLWIRMQQEATREFQEQGFEPMVAETLIYSSGLSNHPIQLWIILFLLYEVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFU5</accession>
    <name>A0A8T0GFU5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G098000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="5768" checksum="46405351D1B665AC" modified="2022-10-12" version="1">MEWDCYCDCDKLASALELLMDHSSDDSVALGFSSICPLPASVGLPFIISKSTPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG89</accession>
    <name>A0A8T0GG89_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G173500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG89"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10242" checksum="C6516CC3121DBD86" modified="2022-10-12" version="1">MVRIVCQWCTSWGLQQRPFQLTKHGIPWRGHVHPKASMCASGDWATRLPLSFELLNAKQEHFNTGSCPVLHAQRSVFLFLFCMSVLFKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGQ7</accession>
    <name>A0A8T0GGQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G011800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035716296" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10645" checksum="1D50A6ED92369E0A" modified="2022-10-12" version="1">MLRFVLPLGIRFLCTSVALAFEEYSCNMVISSRVIRTESTLSKFPTCLFVIFKTSTNYFLYVIYGVVLMPYHHRSIEPKGGYVKRKRRHSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHC8</accession>
    <name>A0A8T0GHC8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G063700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="208"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="56027" checksum="1F5577A764818514" modified="2022-10-12" version="1">MSGLCLELARLTGRSPTETVDTWLDEFGEELVSELLLDTMELERFEQGPDNELRSYLDKKMGTDDNLQFFRLSADFSKIPSWKVIKYRWLLANESESFYRCISTEEQWLRTVIQPQKQNPDAIEIHSNVVPRQAYLTRLAGVMPNCPGRVLCMRGFVPTGVLLRDAEPPRQCCENCTLMTQLRGGAGHTDAAVAKFWEFLNEDVFKTVTGHASLGQGSQGGVEKIMWRKGIFVRKRFDLSQKPYFIREFSVAINVSHPNIVHYFGYSLWSDEAEYSDLYMELLEGDLEKLLFEGARKEEDRLSYEDSLEVLLQIAKAMRHLHERNFVHGDLKPGNIFVSRLPMPHSDAQFCLVKVADFGCAQYVDSNSGATVKPFDYAIGTLHYAAPEVLRCRKHRDSSLIRHPQKIDVYSFGVVAYQVITGVTIVYPKGLRGIRDRVMDGTLRPDDPSLRKLPVLDDDCLSLLRFVRKCWDPNPDERPTFEQICARLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJG1</accession>
    <name>A0A8T0GJG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G121800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="242"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="872"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1175" mass="131664" checksum="4C9E333F09C199A2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJP7</accession>
    <name>A0A8T0GJP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G125400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="11824" checksum="F12141746FFB51DA" modified="2022-10-12" version="1">MSSASSTACTMSEPRAVMADSSTPAATSSHWKITAAWAPEGDDEVTPLLLTTLAACCSVTEVAIADGAAAEWREPDGMGGVLVSKVDVADMTKLFTDRSLNLASTRRRFAWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM44</accession>
    <name>A0A8T0GM44_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G091200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035839652" evidence="1">
        <location>
            <begin position="25"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6741" checksum="083C747EBE2D97F9" modified="2022-10-12" version="1">MRLQSSMAALFLLILLHFGLLSWSAHHCCSGISNTTYQHSFHSHIHVMEGSRIETSAAATT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNR2</accession>
    <name>A0A8T0GNR2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G003000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNR2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="29084" checksum="DD5ECE39303B7B6D" modified="2022-10-12" version="1">MMSNDMTSSQFAPTFPQDFKKFKNNSLSHGKYFAFRILEKRTFSPCQHVVFPRDVFTASVIFPSRLCGTPNIFLLCFRYTYQDVVNPWVANGAVRENSKPKWKRCNPKSSPAEIAILIENTKPLQDPVNFTTGPLTFKVQRNPNCSTSEYGEEMLEVRAKVDYMELFSITAYAFHPAAWMGESLGCGEFLGTTANFPHVGTSPKLQEAGLVWRMGIRRQLEVMGRAEFEYIVVTLAGSEANQHNITFTDASVIYSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ41</accession>
    <name>A0A8T0GQ41_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome c oxidase assembly factor 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G131600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PET191 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ41"/>
    <dbReference type="OrthoDB" id="282149at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033617">
        <property type="term" value="P:mitochondrial respiratory chain complex IV assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018793">
        <property type="entry name" value="Cyt_c_oxidase_assmbl_Pet191"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28627:SF1">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY FACTOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10203">
        <property type="entry name" value="Pet191_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51808">
        <property type="entry name" value="CHCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0559818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7949" checksum="4F30A686A35645C5" modified="2022-10-12" version="1">MAKSCKGLAMELAKCLSDSPCIKDEKRSFKDCAKEKPPSVPSTCVGLRETYFQCKRGQVDMTKRIRGNKGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVF7</accession>
    <name>A0A8T0GVF7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">B box-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G120300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19821">
        <property type="entry name" value="Bbox1_BBX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049808">
        <property type="entry name" value="CONSTANS-like_Bbox1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000315">
        <property type="entry name" value="Znf_B-box"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717:SF60">
        <property type="entry name" value="B-BOX TYPE ZINC FINGER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31717">
        <property type="entry name" value="ZINC FINGER PROTEIN CONSTANS-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00336">
        <property type="entry name" value="BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50119">
        <property type="entry name" value="ZF_BBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="B box-type" evidence="5">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="211"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0562124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="40878" checksum="58043B53061B38E1" modified="2022-10-12" version="1">MTKRRGCELCEGEAALYCAADEAHICWECDAKVHGANFLVARHTRAVLCGGCGMATAGKATGATPVPRAGVCAECAQGESQGECASRDEGSVVDAGRVEVRGVDSGYETGCSSSRGESGLGEVVEEESTVRAEPCESVSQLSGERVGGVTVDSRSVQASVSTGISKVLKRKRLDCCSPVAVPQSKQIATRALEDVNRSVSHRQCDCDSTASSSPSNQSNQRAAHASQDPSLETSFGFNNRAFGTLSLSSAKRQRMDDRTQMRPSLSRHQQLAALPSTARLMRMLAKWHWDLQLSSPGTVPLALRMYRKVSRALAPAVLSNSGVRVTLAACLRLAAGLDEAQITVPKASEVAACAGVSTRRLAMTEIHLLALLGWRRFPVWAGSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVG4</accession>
    <name>A0A8T0GVG4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G056100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVG4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031966">
        <property type="term" value="C:mitochondrial membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005381">
        <property type="term" value="F:iron ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758:SF3">
        <property type="entry name" value="MITOCHONDRIAL SUBSTRATE CARRIER FAMILY PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45758">
        <property type="entry name" value="MITOFERRIN-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="2"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="102"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0563741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="191" mass="20857" checksum="D8CA5C8919792B15" modified="2022-10-12" version="1">MDNPVTQFAGGVLATLVQSSVMVPVEVIRQRQMIQTGGEGTYTGSVHAVKTIVAHEGFGALYRGFLLAQLVWGPYNAVYLPLWEANKRLCVRLSGAESVEKLGVQYELGSAFVSSAFAAGLTNPMDVIKTRLQVQGKKKQYSGALDAAKKIYAHEGYRGFTSGITSRMLWVAPSATIMFTTYDQLMKRLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW81</accession>
    <name>A0A8T0GW81_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G019100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9039" checksum="9D23E817A70106DB" modified="2022-10-12" version="1" fragment="single">DGRIAGNLIQSSVTSDQHRSLKPSARRIIFADVESRSSTAGAAICSKSIHVDRLLVVDRFSLTCYNIPGRCVFSYAHMPFGAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXB7</accession>
    <name>A0A8T0GXB7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_8G010900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXB7"/>
    <dbReference type="OrthoDB" id="1937547at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051032">
        <property type="entry name" value="AP2/ERF_TF_ERF_subfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31985:SF273">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31985">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF042-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="9">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="228"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="162"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="242"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0563197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="287" mass="31034" checksum="9F0F01700F1C2FDD" modified="2022-10-12" version="1">MVEKNANQREAAVIRAAGARGLSLGVTKKEKSQVALKKDDNGSNATSPKYRGVRMRQWGKWVSEIREPNKRSRIWLGSFPTAEMAARAYDAAVVCLRGPNATLNFPDSPSQKLPRCQSPKDVQIAAAAAAAAVEPCTPLSLPAQPVAQSLEAQLHKMESVGELSSQSQITHQSEMQLSPQSQLSVSKKPDKIGAEESASMGESVPTPSTSFVTLDEVDLAWTPDMKLDELPPLDDFLDTTTASSGSKSNLPAPSGDFQREGEFQAYCRQLSGPFESDMMDFSNVFTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXW9</accession>
    <name>A0A8T0GXW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G056300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="15649" checksum="31EF290D650E66A6" modified="2022-10-12" version="1">MSSPASDQHGLSTTSMEQEVLKILKENNAQLRDRVRRLEEEAEQRRMFMIEENRKLEAQVVELQQQLAVQYRELDQVLRLRDSLLFEAEVARLLREEDEEEPINEIDMEMALLQLQEVEADENRRMRLATGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXZ1</accession>
    <name>A0A8T0GXZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G187200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="34" mass="4065" checksum="ABB81F9F1AF82515" modified="2022-10-12" version="1">MLNIFNHSQAAFTCLVLQALWRLCVDHWVVICRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZB9</accession>
    <name>A0A8T0GZB9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G058900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="207" mass="23485" checksum="8BD66D1F519602B6" modified="2022-10-12" version="1">MERRMLLNAFHRTGGRSLQSANPSTDAFWRLCANPLLPRCVRSRITGFITEPDMAIDSHDIPRNPHRGSPRWFFVDKKLNNYGYLPGAPRRDRDALPDIVVNEEKCAKRWGPKQHGKFWYARPGSSESPRMIQRIESLYEVTHQRPNGEAALHWTRLCTGTDCREARARSGLGLLCRQAVSAGGASVHILRRAEKQNKTGVRLVATD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZM7</accession>
    <name>A0A8T0GZM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">aspartate--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Aspartyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_8G117200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>tRNA(Asp) + L-aspartate + ATP = L-aspartyl-tRNA(Asp) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="3"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZM7"/>
    <dbReference type="OrthoDB" id="372395at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017101">
        <property type="term" value="C:aminoacyl-tRNA synthetase multienzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04320">
        <property type="entry name" value="AspRS_cyto_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00776">
        <property type="entry name" value="AsxRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.930.10:FF:000013">
        <property type="entry name" value="Aspartate--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000132">
        <property type="entry name" value="Aspartyl-tRNA synthetase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="entry name" value="Bira Bifunctional Protein, Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003483">
        <property type="entry name" value="PRK05159.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450:SF1">
        <property type="entry name" value="ASPARTATE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="ASPARTYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="Class II aaRS and biotin synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminoacyl-transfer RNA synthetases class-II family profile" evidence="13">
        <location>
            <begin position="230"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0564520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="535" mass="59893" checksum="BC042032CC3E65CC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1L5</accession>
    <name>A0A8T0H1L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G013900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1L5"/>
    <dbReference type="OrthoDB" id="277802at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005689">
        <property type="term" value="C:U12-type spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097157">
        <property type="term" value="F:pre-mRNA intronic binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030626">
        <property type="term" value="F:U12 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045164">
        <property type="entry name" value="RBM41/RNPC3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16105:SF0">
        <property type="entry name" value="RNA-BINDING REGION-CONTAINING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="420"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="25"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="98"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="209"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="123"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="209"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="475" mass="51236" checksum="365C5BD5EFC2847B" modified="2022-10-12" version="1">MAAMVPPPPLPGVSSSVPSVEGSRITLLIRHLPEGLPADTLKRLFSHYGASDFRLCQSGKMKNCAFVDYDNEAAAAAAQSQMHRLRFLGKVLSVERATPASSKDGLSEDNSMMTSTGEGTETAPPPPLPPVPQSGEAVQAGRVASGREPIAPSLGVDYPFPPQLEYAYPPPDGNILTNIVNTLIAVPRFYTQVLHLMNKMNLPAPFRPALPTPPLPPPVPAPVAEKRQAGELSSGESELESSDEEDNNALGGEDETDAAEKELDTHKARRKRAKLEAVVGPAVDKGASHEAAGLKYINIIPKTAPIKKNKPVMQIKISTKASVGEGASRDIGNQEEMDITREEVDDPARTATRAELQAGQLSEAEFLSLSILKNYSAGTPSQVLYIKNLAKEVVSEDIFYVYGAFFPSLEEGKNALNVNLMQVLTCASLFLVSILIHALIFVINPSFEFPVYYSSKDSTADLIFVAHLQLVERSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H476</accession>
    <name>A0A8T0H476_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isopenicillin N synthase-like Fe(2+) 2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G199200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H476"/>
    <dbReference type="OrthoDB" id="438224at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48253">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48253:SF2">
        <property type="entry name" value="ISOPENICILLIN N SYNTHASE-LIKE FE(2+) 2OG DIOXYGENASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="493" mass="53961" checksum="A27EAC37ADD041F2" modified="2022-10-12" version="1">MLVLDYHQLVALSRHGSNPHQRNNGALLSVQEPGDDGRAEPDWGVADSCMEAMGPNGDGFVAVRGMRDYASLRSRLLRLAQTLALMPTSERAAVLKEHGLGTDVPLKDPGRPVSSFAAQLWFGSLREFKQSEPTLIDDCGGLNAHWSSDGDSLSDLGSLFKQLGMCMVEVGLLIARLCDAARSQGSMREARLEQAILESGTAKGRLIHYHSSLEQEIMSSLRKDFRKGHKQNKSGDGGRKTDISNLATDFAGSAPTWWQQWHCDYGIFTVLTSPLFLRPTRVIPVNSNVGMERSCCLKDVPMSAGIQLQANLELPKLNSSRVIHQGKMEGKSPRTRSPQLSSSPPRLVDLNSSVQECLSPDGHSLLVVMDSHGRTTSLVIPSDYLIVQVGEAAQLLCGGELVARAHCVMRPTSAKDVSRETMAVFLQPAWDRRMTLPLGVPQEQALEAGGNATNLETHIPQLASRWKDGCTFAELSKETTRQYYGADGYQSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6H4</accession>
    <name>A0A8T0H6H4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="11">dUTPase</shortName>
            <ecNumber evidence="4 11">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 11">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G021300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>dUTP + H2O = dUMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4 11"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6H4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.40.10:FF:000004">
        <property type="entry name" value="Deoxyuridine triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001862">
        <property type="entry name" value="PRK00601.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241:SF0">
        <property type="entry name" value="DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="dUTPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase-like" evidence="12">
        <location>
            <begin position="133"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU367024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0565889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="268" mass="28995" checksum="BC66EA537F6A0C25" modified="2022-10-12" version="1">MAAGEFGPGGSHSSLSLRFDILVFKNLPHCPRRRFRCSFELGGAKLIRGERFIFRAVHWIFSRRRLMLCSRFWGLKLSSASSLVLARLQSAGKQKSKVVAMEPQPKVQKLDHHNAKVVQVASQALRVKKLAAEAILPSRGSALAAGYDLSSAYDTKVPARGKALVKTELSIAIPEGTYARVAPRSGLAWKNSIDVGAGVIDADYRGPVGVILFNHSDSDFPIKAGDRIAQLILELIVTPDVMEVEDLDATVRGEGGFGSTGVSLVVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7V3</accession>
    <name>A0A8T0H7V3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec1 family domain-containing protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G179400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STXBP/unc-18/SEC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1910">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001619">
        <property type="entry name" value="Sec1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027482">
        <property type="entry name" value="Sec1-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036045">
        <property type="entry name" value="Sec1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11679">
        <property type="entry name" value="VESICLE PROTEIN SORTING-ASSOCIATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00995">
        <property type="entry name" value="Sec1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56815">
        <property type="entry name" value="Sec1/munc18-like (SM) proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="784" mass="85268" checksum="3F02D849CD77C9EF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H860</accession>
    <name>A0A8T0H860_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">chlorophyll(ide) b reductase</fullName>
            <ecNumber evidence="13">1.1.1.294</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G063900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>7(1)-hydroxychlorophyllide a + NAD(+) = chlorophyllide b + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24768"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83356"/>
            <dbReference type="ChEBI" id="CHEBI:83357"/>
            <dbReference type="EC" id="1.1.1.294"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>7(1)-hydroxychlorophyllide a + NADP(+) = chlorophyllide b + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24772"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:83356"/>
            <dbReference type="ChEBI" id="CHEBI:83357"/>
            <dbReference type="EC" id="1.1.1.294"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.294" evidence="13"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H860"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034256">
        <property type="term" value="F:chlorophyll(ide) b reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010304">
        <property type="term" value="P:PSII associated light-harvesting complex II catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05233">
        <property type="entry name" value="SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000223">
        <property type="entry name" value="Chlorophyll(Ide) b reductase NOL, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052625">
        <property type="entry name" value="Chl_b_Red"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314:SF21">
        <property type="entry name" value="CHLOROPHYLL(IDE) B REDUCTASE NYC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24314">
        <property type="entry name" value="NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0881">Chlorophyll catabolism</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="6" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00050138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00066856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0566439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="634" mass="68704" checksum="C10DBCC9DE8FA64E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9S3</accession>
    <name>A0A8T0H9S3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_7G097600</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9S3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000129">
        <property type="entry name" value="Leucine-rich repeat receptor-like kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000198">
        <property type="entry name" value="receptor protein kinase TMK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000226">
        <property type="entry name" value="receptor protein kinase TMK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052422">
        <property type="entry name" value="Auxin_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986:SF1">
        <property type="entry name" value="OS04G0685900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47986">
        <property type="entry name" value="OSJNBA0070M12.3 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="13 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-0675">Receptor</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036435063" description="Protein kinase domain-containing protein" evidence="20">
        <location>
            <begin position="27"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="535"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="643"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="470"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="593"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="18">
        <location>
            <begin position="967"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="470"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="18">
        <location>
            <begin position="495"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="18">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="18">
        <location>
            <begin position="605"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="671"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0566929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="994" mass="105587" checksum="5AA9B2623FDD6518" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAQ7</accession>
    <name>A0A8T0HAQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G175200</name>
        <name evidence="15" type="ORF">KC19_7G175700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Required for the correct development of pollen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAQ7"/>
    <dbReference type="OrthoDB" id="27652at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02663">
        <property type="entry name" value="Peptidase_C19G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000035">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF733">
        <property type="entry name" value="RE52890P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-0519">Myristate</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="USP" evidence="13">
        <location>
            <begin position="25"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00053800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0567959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0567965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="42504" checksum="971DB28683CCF2E1" modified="2022-10-12" version="1">MVMGSSGSKLEKALGDQFPEGERYFGLENFGNTCYCNSVLQALYFCVPFRDQLLEYCGQNKAVQETEENLLTCLSELFTQINSQKKKTGVIAPKRFVQRVKKQNELFRSYMHQDAHEFLNFLLNELVDILEKEAKAAKSNSGPQASPEKAVANGSVNGLSNGNHKEPIVTWVHKIFQGTLTNETRCLRCETITARDETFLDLSLDIEQNSSITSCLRNFSSTETLNAEDKFFCDKCCSLQEAQKRMKIKSPPRILALHLKRFKYIEQLGRYKKLSYRVVFPLELKLCNTTDDAPGSEAEYSLFAVVVHVGSGPNHGHYVSLVKSHNHWLFFDDENVEIIDESIVQTFFGSTQEYSNNTDHGYILFYESLEQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBF5</accession>
    <name>A0A8T0HBF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G064500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF11">
        <property type="entry name" value="OS04G0670900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="133"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="416"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="382"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="422"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="52764" checksum="9F524C2E1F60F57C" modified="2022-10-12" version="1">MHSCVELGGQVMSSISWDYVFNESDQSPWFESPYGDPCVYLDDPLRSLYALDQTFSASGSASDSHLHGSSQEGVANVPSVDVSELPPLFNEDLPHTKLFLSYVEEHIKKYFLSVGDPVQSNEITSVEDHEESSKRHRSPNWIPEENLPFLELKEEAQEKGMGKPWNYISEGLRDRYNFDRSAKVCEDHWGTLLKGFKAIRKNESSRPCVSYWDMDNDERSRKKLPPTFLLEWYKMMEGIELAGKKKRPRSADHGGNQTSDRKYSGTKGFGATLEENSHLLKKLGPFIKRQIGDYVDSEVEGVGFRMTSNVTSKQEAILTSMIPHVKHQVEAAAISALELSILTGKFVGDEQDLITMLASDVGIRKIIKDALDSALQPVAFDLQALAQEEQKDQARLQAIEEQKRALDLEAKNIISKRRRGGRHDQRAQETSKRQVPRGKNYSTAGKIVPKFKGLRIAGDQGGVSILEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFF9</accession>
    <name>A0A8T0HFF9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <ecNumber evidence="8">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G168200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="8"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFF9"/>
    <dbReference type="OrthoDB" id="60984at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009051">
        <property type="term" value="P:pentose-phosphate shunt, oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.360.10:FF:000018">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000222">
        <property type="entry name" value="Glucose-6-phosphate 1-dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.10">
        <property type="entry name" value="Dihydrodipicolinate Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429:SF22">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55347">
        <property type="entry name" value="Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 8" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase NAD-binding" evidence="9">
        <location>
            <begin position="103"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Glucose-6-phosphate dehydrogenase C-terminal" evidence="10">
        <location>
            <begin position="284"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0570516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="588" mass="65868" checksum="08523C3BB92D8BD1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGE7</accession>
    <name>A0A8T0HGE7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Small ribosomal subunit protein uS15c</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G136200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGE7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.3130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_uS15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_uS15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47546:SF3">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S15, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47546">
        <property type="entry name" value="S15/NS1, RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="57"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00035250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="27023" checksum="5B14CB60990A0354" modified="2022-10-12" version="1">MASRVQSRLLRPLLQRSGVCAGVREVSTFNPLRSPENDTTARGETEDFASKILLEMRGRKGEEKQASSEESVPDSGSSYLSQLTMRGLKARTEDGAPAESPLQKLGQLSRLGDMNQGPGYMFLPPKEHLLEKYYADEHLSAMERQKMELKKVREEYRIHEGDCGSSQVQIALLTAKIKYMAEHMKTHKKDLHSRKGLEGMLEQRKKLLKYLRRTDWDEYCILITRLGLRDKPNEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHP1</accession>
    <name>A0A8T0HHP1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G041200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07383">
        <property type="entry name" value="MPP_Dcr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000172">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011230">
        <property type="entry name" value="PAP14/16/28/29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF11">
        <property type="entry name" value="METALLOPHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030250">
        <property type="entry name" value="Ptase_At2g46880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="52"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="385" mass="42279" checksum="6E2E1D928AA5BD77" modified="2022-10-12" version="1">MMRSGCRMSLVMWIRVWVMVAAVVDVLGGGCLIAAGMEVGCGVRFKDEVASFKVAIFADLHYGENAWDEWGPRQDVNSTAVQSFLLDHERPDFVVYLGDLITANNLPCHDAVLHWFQAVGPAVDRKIPFASVFGNHDDASFEWDPHSGVGPDEPLQTTSRTELMDFDMSLPSSYSSSGPKTLLPSVSNFFVPIASSDGTRIVAIMYFLDSGGGSMAEFISADQIAWFTTTASKFNSDASIPELVFWHIPSIAYTRSGPKPNQPIEAPCVGSINDESIAPQETEWGIMNVLTNRSSVKAVFVGHNHGLDWCCPYNNLHLCFARHTGYGGYGKWKRGARFVEILQEPTTLQIRTSVTLEDGSVVSELILALDKVEPYIQQNVASSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHS5</accession>
    <name>A0A8T0HHS5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G122200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1146"/>
            <end position="1206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1241" mass="140102" checksum="4EA2059A979F1D53" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHV4</accession>
    <name>A0A8T0HHV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G048000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004392">
        <property type="term" value="F:heme oxygenase (decyclizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006788">
        <property type="term" value="P:heme oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19165">
        <property type="entry name" value="HemeO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000002">
        <property type="entry name" value="Magnesium/cobalt efflux protein CorC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002051">
        <property type="entry name" value="Haem_Oase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016053">
        <property type="entry name" value="Haem_Oase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777">
        <property type="entry name" value="HEMOLYSIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22777:SF17">
        <property type="entry name" value="UPF0053 PROTEIN SLL0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01126">
        <property type="entry name" value="Heme_oxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="324"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="529"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="597"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="727"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="804"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="897"/>
            <end position="936"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="728"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="815"/>
            <end position="834"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0568832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="936" mass="103820" checksum="751D3DD1855A894A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIH8</accession>
    <name>A0A8T0HIH8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Bystin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G164800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bystin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIH8"/>
    <dbReference type="OrthoDB" id="2192561at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030688">
        <property type="term" value="C:preribosome, small subunit precursor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.480:FF:000001">
        <property type="entry name" value="Bystin (51.6 kD)-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007955">
        <property type="entry name" value="Bystin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12821:SF0">
        <property type="entry name" value="BYSTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05291">
        <property type="entry name" value="Bystin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00074032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="468" mass="53905" checksum="4A8401CE37736626" modified="2022-10-12" version="1">MASQMKPRAPAQHKKKRKDAGPEKHGLSLGDQMEQNQEALPPKRRHPRNRNRQQAQDEYVTPVMSNKILGEARMQQLEIDNERDEETGVAATRRAFTAVVPDQRMDSDSDNDEDGFSDGEDIPEEFEEVTEEDERIISMFMASDAAPQRTLADIIMERINDKGGDAMVATEEEGGGRTIPGVDSKVIEVYQGVGKLLSRYRAGKLPKAFKIIPSLSNWEDVLFLTEPERWSPNAMYQATRVFASNLNARMAQRFYNLVLLPRIRNDIREHKRLHFALYQAMKKAVYKPSAFYKGLLLPLCQSRTCNLREAVIIGSVLQKVSIPVLHSSVALLKIAEMEYCGTNSYFLKLLLDKKYALPYRVLDSVLAHFVRFIEDDRDLPVIWHQSLLTFIQRYKNELSEDDKEKLKQLMRKQKHYLVTPEIHRELLNSRNRGQKDENMSVIPMKIEKAVVEEDMWNLPEVQIGMDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ53</accession>
    <name>A0A8T0HJ53_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G190200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ53"/>
    <dbReference type="OrthoDB" id="45365at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="CDD" id="cd22152">
        <property type="entry name" value="F-box_AtAFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344:SF27">
        <property type="entry name" value="KELCH REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46344">
        <property type="entry name" value="OS02G0202900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="3">
        <location>
            <begin position="62"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0570826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="483" mass="53628" checksum="B9312EA27EE55A63" modified="2022-10-12" version="1">MLLEFALRVLRCVYADIVIAMGNFLSSARSQEDEVLIANNDSQKRQRISIEYEQQPAIIPGLPEEIALQILARVSRGNHPLLRCVCKSWHQVLSTPEIFNLRKELGVTEEWLYVLMKDEEERLGWHVLDPVDGKWRKLPPMPEIANIAKKPETAETSWGWRIPLGPLRTMRFAGLFRGWFQRKGFLDKTPFCGCSAGAINGSLYVLGGFSWASAMRAVWRYDSRTNRWASSAAMEVARAYCKTGVVDNKLYAIGGVDRGRGGLTPLQSAEVYDPETDSWSQVAPMPFRRAQVLPTAFLADMLKPIATGMAAYNGKLCVPQSLYSWPFFVDVGGEIFDPATDMWAEMPIGMGEDWPARQAGTKLSVVVGGKLYALDPTSSMDGSKIKVYDSDQDVWKVVLKKVPILLDLSDSESPYLLAGFDGKLHVITKDINDNVAVLRAELGSDNSNSSQQAVKDSVEFGWKTISSASFGTVELVACQVLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJM9</accession>
    <name>A0A8T0HJM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alcohol dehydrogenase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G203400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJM9"/>
    <dbReference type="OrthoDB" id="417550at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051903">
        <property type="term" value="F:S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046294">
        <property type="term" value="P:formaldehyde catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43880:SF56">
        <property type="entry name" value="ALCOHOL DEHYDROGENASE-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="120" mass="13189" checksum="058E9DFA60FE1D61" modified="2022-10-12" version="1">MTDGGVDYSFDCTGDVGVIKSALECCVEWGGVSCILGLVESSQRVKFHPASLLWGRAWTSGLFGGYKGRTELPGLVDRCIKGHINLDHYITHKLPFSKINEAFTLLNQGGCIRCVMDYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJP7</accession>
    <name>A0A8T0HJP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G205600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005459">
        <property type="term" value="F:UDP-galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005460">
        <property type="term" value="F:UDP-glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037185">
        <property type="entry name" value="EmrE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013657">
        <property type="entry name" value="SCL35B1-4/HUT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10778:SF10">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35 MEMBER B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08449">
        <property type="entry name" value="UAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103481">
        <property type="entry name" value="Multidrug resistance efflux transporter EmrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="202"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="299"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0571020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="325" mass="35917" checksum="B98F2897C95DF237" modified="2022-10-12" version="1">MEKSGGGSQVLMLGVCVAAIYAAYITQGVVQENVSTKRYGEKGERFEQLTFLNLAQSVVCFVWSMLMLQLWPNKKGSQAPVTAFWSPGISNAIGPACGIVALKYISYPAQVLAKSSKMIPVMFIGALVYGVRYTLPEYLCTFLVAGGVSIFALFKSSKKVVSKLANPNAPLGYALCFLNLGLDGFTNATQDAITKKYPKTNAWHIMMGMNLWGSIYMSLFMFGWPSGGGWEAVKFLQEHPAAAWDIFLFCLCGAVGQNFIFLTISRFGALTNTTITTTRKFVSILVSAIWNGNRLSSQQWAGVFMVFSGLMYQIYLKWRKRKRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK67</accession>
    <name>A0A8T0HK67_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G216500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK67"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000042">
        <property type="entry name" value="probable strigolactone esterase DAD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43039">
        <property type="entry name" value="ESTERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="24"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0571168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="29644" checksum="2D3D63454BC3A402" modified="2022-10-12" version="1">MIPSSSSLLASHNVTIVGNGDQYVVLSHGFGSDQSVWKYVLPYLVNDYKVILYDLMGAGTTNPDDFSFNRYSSLHAYADDLLAILDELEIESCVYVGASVSGMVGCLASIERPEVFKKLVLLASSPRYLNDVGYYGGFNQEDLDQLYGDMKSNFKSWVTGFGPLAVGSGLESSAVQEFSGTFYSMRPDIALSVSKTIFQSDLRATLPLVTVPVHLLQTTKDMAVPFDVADYMLRHLGGWTTMEILNTEGHLPHLSDPNVVIPALLRCLSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMH4</accession>
    <name>A0A8T0HMH4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG062100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMH4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="245" mass="26674" checksum="7C21798E9D2FDB50" modified="2022-10-12" version="1">MNQKTEDDTWNPLLEDDDPDYLNWNESEASLASESMNQINMLQATTGSNPMSEEAILSTPVPVSFDDRTPSSKAGSVQEMEARPTSQRSLNQRLFTFETELKRSIFQWQDNVQNQLDVNHTKMTSMERKLDMVLDMHASLIMKSASKAIGTNPSDDVLVNDNTVSPGICTQQTGCPSVEWQTPLACEKTSSGSGPSVDLCGNDVSHVGGDGGIDSEGILQGRSCEIPFEFPSVGGVAQEKCSSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNA0</accession>
    <name>A0A8T0HNA0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG083900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNA0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="98" mass="11368" checksum="011EDFAEAB780E79" modified="2022-10-12" version="1">MEWHYDSNEIAKISLRRNSKEAMVHGVGGRNYVIGERIIVARRPVDIFLRIIVARRPVDYIGWFAGCLRTLGRYPFLSEPDYPINITEYCQILITLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNX3</accession>
    <name>A0A8T0HNX3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA (cytosine-5-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG106600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="1"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050390">
        <property type="entry name" value="C5-Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23068:SF25">
        <property type="entry name" value="DNA (CYTOSINE-5)-METHYLTRANSFERASE DRM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23068">
        <property type="entry name" value="DNA CYTOSINE-5- -METHYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="639"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="650"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0572572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="691" mass="77871" checksum="31CD22F2A2D2EF42" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPL4</accession>
    <name>A0A8T0HPL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_VG117900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000021">
        <property type="entry name" value="Glutamate-1-semialdehyde 2,1-aminomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000012">
        <property type="entry name" value="Glutamate-1-semialdehyde 2,1-aminomutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000818">
        <property type="entry name" value="PRK00062.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43713:SF3">
        <property type="entry name" value="GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0572695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="571" mass="60360" checksum="7DA074CD38C9398C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ34</accession>
    <name>A0A8T0HQ34_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG141000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12296" checksum="880863F08C421A04" modified="2022-10-12" version="1">MIPMNPLHPLPLCLLEVIPKITRSRHPPTVVLMVMEVRIQKVLMKWVMNPLCPSILSVTIHRSTTRLLRRPPAKTVHTIRSPLGRRRASPGRKVEQTRLLSVTTLSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ41</accession>
    <name>A0A8T0HQ41_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG118700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ41"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="12662" checksum="DF38FE95C9043521" modified="2022-10-12" version="1" fragment="single">SQVALYLREPSMRAISIAIAATVDALSPHPRPDPRLPHSSHCQPRLVAHAGIARSSQQCSAPQCSISCTSGLSLSCTSSSQGSGPGCQFEVAASQVRCRKFVAGGLLIRAQDVAMMPGTCAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HR49</accession>
    <name>A0A8T0HR49_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome b6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_VG177400</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">The 4 large subunits of the cytochrome b6-f complex are cytochrome b6, subunit IV (17 kDa polypeptide, PetD), cytochrome f and the Rieske protein, while the 4 small subunits are PetG, PetL, PetM and PetN. The complex functions as a dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HR49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00284">
        <property type="entry name" value="Cytochrome_b_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.810.10">
        <property type="entry name" value="Cytochrome Bc1 Complex, Chain C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00633">
        <property type="entry name" value="Cytb6_f_cytb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005797">
        <property type="entry name" value="Cyt_b/b6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023530">
        <property type="entry name" value="Cyt_B6_PetB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027387">
        <property type="entry name" value="Cytb/b6-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048259">
        <property type="entry name" value="Cytochrome_b_N_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002990">
        <property type="entry name" value="PRK03735.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19271:SF16">
        <property type="entry name" value="CYTOCHROME B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00033">
        <property type="entry name" value="Cytochrome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000032">
        <property type="entry name" value="Cytochrome_b6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="Transmembrane di-heme cytochromes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51002">
        <property type="entry name" value="CYTB_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b/b6 N-terminal region profile" evidence="15">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="16">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00035697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0573422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="201" mass="22796" checksum="75CE592A63435C04" modified="2022-10-12" version="1" fragment="single">YDWFEERLEIQAIADDITSKYVPPHVNIFYCLGVATGFAMTFYYRPTVTEAFASVQYIMTEVNFGWLIRSVHRWSASMMVLMMILHIFRVYLTGGFKKPRELTWITGVILAVLTVSFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSVSVGQSTLTRFYSLHTFVLPLLTVVFKLMHFLMIRKQGISGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS92</accession>
    <name>A0A8T0HS92_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG177000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS92"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="47" mass="5569" checksum="F04D07542052F256" modified="2022-10-12" version="1">MPTIQQLIRNRRQPVENRTKSPALRGCPQRRGVCTRVYVRLVMVKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTE9</accession>
    <name>A0A8T0HTE9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Reverse transcriptase zinc-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG246300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026960">
        <property type="entry name" value="RVT-Znf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13966">
        <property type="entry name" value="zf-RVT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase zinc-binding" evidence="1">
        <location>
            <begin position="68"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="283" mass="33056" checksum="720D6C979E19E1A9" modified="2022-10-12" version="1">MCLQFSNLLNVEFSDLANTARLLASVNFVLDDVSSKVLFISPKSPHNLLCGHTKSPQVLLLSVEGDYRLLWKSVSPKERTRKESSLMWLIWHRAVAVNHWRGRIDGNVDIRCPICHRGSEESVLHRFWECESSQRAWQFAIHIMNQLVKGKDVRGPWQPLSWKQGIFSYRIPRKFDAFKQIWLELRSVVLWTLWIERNDIVFNNQRWPPAKLLQQVKTGIIDYGRVEWDNLTRIKPGDSEPRSASLGPFIDRRCRFDIFDSMGLGKPWWMLSAPLEGFVFQPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVF5</accession>
    <name>A0A8T0HVF5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG266500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11317" checksum="B08A588EA0B25783" modified="2022-10-12" version="1">MKRVYGEISHGGPCDVVGVRAWLRRVQLYAEVNWETELPSYSAITHLIDDDFVFDWTPLCSRQYEAVAAVTAVTGIVHVDNFVVSVLLGRDYVEASPMNSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVJ5</accession>
    <name>A0A8T0HVJ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG287700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="9276" checksum="C2689B8F87DFF05D" modified="2022-10-12" version="1">MDASPALEAAMSATDADSPLDSLGLWCRVPVCAISIGVSGCNTFSAHIRTCPCRAQSMGLSSTHSVQKHASCRVCKYVTVVGEREDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I177</accession>
    <name>A0A8T0I177_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RNA-binding protein 25</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G098600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I177"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1390.10:FF:000008">
        <property type="entry name" value="RNA Binding Motif protein homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.10">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002483">
        <property type="entry name" value="PWI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036483">
        <property type="entry name" value="PWI_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053294">
        <property type="entry name" value="RBM_PWI_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47334:SF2">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47334">
        <property type="entry name" value="SPLICING FACTOR PWI DOMAIN-CONTAINING PROTEIN / RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01480">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00311">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101233">
        <property type="entry name" value="PWI domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51025">
        <property type="entry name" value="PWI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="152"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="PWI" evidence="5">
        <location>
            <begin position="790"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="319"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="565"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="705"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="269"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="388"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="709"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0576675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="888" mass="100519" checksum="CF91493B917EF71E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1W6</accession>
    <name>A0A8T0I1W6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exocyst subunit Exo70 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G156100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Component of the exocyst complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the EXO70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1W6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005546">
        <property type="term" value="F:phosphatidylinositol-4,5-bisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.170">
        <property type="entry name" value="Exocyst complex component Exo70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016159">
        <property type="entry name" value="Cullin_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004140">
        <property type="entry name" value="Exo70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046364">
        <property type="entry name" value="Exo70_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542">
        <property type="entry name" value="EXOCYST COMPLEX PROTEIN EXO70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12542:SF85">
        <property type="entry name" value="EXOCYST SUBUNIT EXO70 FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03081">
        <property type="entry name" value="Exo70_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20669">
        <property type="entry name" value="Exo70_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74788">
        <property type="entry name" value="Cullin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex subunit Exo70 C-terminal" evidence="5">
        <location>
            <begin position="292"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="659"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU365026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="681" mass="76710" checksum="E2EAC4E6A170C81F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2X9</accession>
    <name>A0A8T0I2X9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_5G152200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2X9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.540:FF:000001">
        <property type="entry name" value="Phosphomethylpyrimidine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.540">
        <property type="entry name" value="Radical SAM ThiC family, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00089">
        <property type="entry name" value="ThiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037509">
        <property type="entry name" value="ThiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038521">
        <property type="entry name" value="ThiC/Bza_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006763">
        <property type="entry name" value="PRK09284.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009895">
        <property type="entry name" value="PRK13352.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00190">
        <property type="entry name" value="thiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557:SF1">
        <property type="entry name" value="PHOSPHOMETHYLPYRIMIDINE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30557">
        <property type="entry name" value="THIAMINE BIOSYNTHESIS PROTEIN THIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00407">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01114">
        <property type="entry name" value="phosphomethylpyrimidine_syntha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00113">
        <property type="entry name" value="Radical_SAM_Phosphomethylpyrim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="7" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0577377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="675" mass="74751" checksum="449188292DFDC0BC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3G1</accession>
    <name>A0A8T0I3G1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_5G136300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000146">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase IOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000415">
        <property type="entry name" value="receptor-like serine/threonine-protein kinase NCRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0675">Receptor</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="446"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="15">
        <location>
            <begin position="509"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="537"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0577173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="846" mass="92421" checksum="112D9C584A603E90" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5C2</accession>
    <name>A0A8T0I5C2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G013300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Plastid</location>
            <location evidence="1 8">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5C2"/>
    <dbReference type="OrthoDB" id="423598at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000007">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="3 8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 8" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4 8" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5 8" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0793">Thylakoid</keyword>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>6</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0578307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="32590" checksum="5F996A6B3F7551D8" modified="2022-10-12" version="1">MAAMAAAKAEFLGQSVVASKSDVVAQKQGGLRVVSLFSKGKKAVAKATKEVKKAAPKVAPKAASAAKKAVAKVNRPDNEELAKWYGPDRRIYLPEGLLAKEEIPAYLTGEVPGDYGYDPFGLSKKPEDFDKYQAYELIHARWAMLGAAGFVLPEAFNKFGAVCGPEAVWWKTGALLLEGDSIQYFGATIPINLAAAVIAEVVLVGGAEYYRSTNKSPLGSDLDRLHPGGAFDPLGLAKDPDQFALLKVKEIKNGRLAMFSMLGFFVQAYVTGEGPVENLSAHLSDPFGNNLLTVIQGTAERVPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6M9</accession>
    <name>A0A8T0I6M9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G091100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6M9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="15311" checksum="B4B9C232C10AB6F8" modified="2022-10-12" version="1">MTSCDTYIAMYWITVVVILAVMISDVAARELSGSPMASPNATIVKSQDKVLNWLNITLVPLGVSLIGLCIWGCIKKSDIWRSLTCEHRSASIAPEANEMRSAHELPNNSSHDGSDLEEGIALSERGVDEGPAMTAETLPIPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9P9</accession>
    <name>A0A8T0I9P9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G114100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9P9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="31403" checksum="0679271F376BD07F" modified="2022-10-12" version="1">MPQYWVMPGTGLPAVRIAGDDDDFFRRATRSLDKLNGTVAGHALLTALANRRAAVPALNVTIHLTTEINQCAGIPRTIAGAAVSDGRTLLAQALIDGLGNIPGEIQDCLNAMDPPMLGIAGHAWLANAVNMTPIYNIEGMPPLPQSVIRLTANDVTNWINGVTIYPAPIPAARREDLALLLLTVLWPGSRNRPGNGLHSRVNWDPTKRQITLTNGVVLRGSKTVSLAHELTHALYNGEGQQLGNENGHFSSVLYEYMCVGLGPWATEECSENKYRAEWTRPTLELRPCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAH7</accession>
    <name>A0A8T0IAH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G141400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8445" checksum="D308FB24061782F4" modified="2022-10-12" version="1">MNTCYELLIDPNPCCNETIQKVLENRLRVVSSDFNATPLRQCFGAEQSRLCHSYICSFIQSARIFQVKMHNSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICT5</accession>
    <name>A0A8T0ICT5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G232900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35381">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35381:SF1">
        <property type="entry name" value="EF-HAND DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="135"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="831" mass="96191" checksum="0789F9700B65E82E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE58</accession>
    <name>A0A8T0IE58_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G228600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006301">
        <property type="term" value="P:DNA damage tolerance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039577">
        <property type="entry name" value="Rad18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027370">
        <property type="entry name" value="Znf-RING_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RAD18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14134:SF3">
        <property type="entry name" value="RING-CH-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13445">
        <property type="entry name" value="zf-RING_UBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="174"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0581161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="285" mass="31649" checksum="2B2412688ADFF348" modified="2022-10-12" version="1">MDIENLSVLNSGWLSCGSSASSPSSVIDDSSTCPICFALMKPPHLAPIILTPCGHTFCAKCIAVHTAVQRKKARLVGGPISAPPCPQCKATIMAQCVNITLQNIITERLAIEENMRRAEIESIYPKTPVRGQLLYEELVTSRKADFARTARDKFGVHVNTSPGPLCCHSLQDALLETRHRQDRLEMDLSSAEEKLNLLDSREKELKQILQKASLEHRMVQSELEDTKSKKGMLHQAHADTLKKSQLIEASMVAMTFEKECERSRSLGPTTKEIEDICSAHFWSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEU2</accession>
    <name>A0A8T0IEU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G248500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040014">
        <property type="entry name" value="CIR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019339">
        <property type="entry name" value="CIR_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041670">
        <property type="entry name" value="Znf-CCHC_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151">
        <property type="entry name" value="CBF1 INTERACTING COREPRESSOR CIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13151:SF2">
        <property type="entry name" value="COREPRESSOR INTERACTING WITH RBPJ 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10197">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15288">
        <property type="entry name" value="zf-CCHC_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01083">
        <property type="entry name" value="Cir_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBF1-interacting co-repressor CIR N-terminal" evidence="2">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="54720" checksum="3A1EB7C59CA4A9B1" modified="2022-10-12" version="1">MKKTGNEEVEYKQKSGTAWSHSYLNQKPWHPLSYPNQRRKWIAEQQNAQKARKAEEVAHEFSQQQEFFRQTAEMNRREKEKVEALQAVSFMYMRPPGYNAESARAAEIADERKLLGIDAPPSSSQDASLAVTSHGEAGGVELEVKKKPRVKDVFGRNVATEEEFAVLKDAPKMDTGVVGRVKPFAIEIRNVKCAKCGGFGHQSGDRECPLKDVITPNEMERLKRNDPLNAIIAQATGDEPFKWELKNQPGAMSPARGGFRPDDPNQQILADEDIYDEYGGFLAGGGIGDESDGEGKLPIPDILASLTKEQRKELAALRVDEKKWKREDRRKKRKKKRKSRRDGSSDESSDEDYDRKGKQHRHKNRSHKHRKRSQSDTHRSDRGHHRKHHHSDSTSSCTSSELDHAATASESRDVSSRKKLEGSDDSNVQRAAVHERHYRSHRSSRTKDRDRDRERKVARDTVLDEVYENFKRQRKKDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEU5</accession>
    <name>A0A8T0IEU5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G259500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="16536" checksum="9A83006323005E23" modified="2022-10-12" version="1">MGSPKHNQEGKKKNPESHSGDVQIINAHAQFRYLSGSSYVHNRSSTSLIFALWQSGHFFQRTHTHFQPTYAIRDTLPTPFKQHPKDIMSCTSQLIPGKLLNSMLRRRTFLNNGSQNTCGRAHKTYTITLPDVHDSPPMLCNCSLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEY8</accession>
    <name>A0A8T0IEY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Calcineurin-binding protein cabin-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G222800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031491">
        <property type="term" value="F:nucleosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033053">
        <property type="entry name" value="Hir3/CABIN1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15502:SF7">
        <property type="entry name" value="CALCINEURIN-BINDING PROTEIN CABIN-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="118"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="350"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="501"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="642"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1269"/>
            <end position="1297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="354"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="384"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="402"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="436"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="507"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="642"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1271"/>
            <end position="1284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0581073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2217" mass="244490" checksum="31F6674E5FC2DAF9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF71</accession>
    <name>A0A8T0IF71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G053900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF71"/>
    <dbReference type="OrthoDB" id="1988819at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035742249" evidence="2">
        <location>
            <begin position="22"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="178" mass="18530" checksum="F27ABC14AE5BAF7F" modified="2022-10-12" version="1">MAKLLCFVAVLLVASAILAEAHTAPATPPTGSKSGSKSTAAPVPAPAPSVRGLIKKSATFSLKCIIHNLADRSLTFKLVIQRKDAAKAVVAKAKQWTAIGPVTVGCKVPVVQLYVTVKTNKGVVVTKSFPVKLAAFLKNIVPKSSKALVVTASEVKSLLGGKKLVIKVGRKVELSVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFG6</accession>
    <name>A0A8T0IFG6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G235700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFG6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5826" checksum="C6FF6B8B1D2A2F89" modified="2022-10-12" version="1">MAMCSFVFHMLIFYLNCITINNFTSFAARSEIRLRSDTIGSSGVPKLCTEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG37</accession>
    <name>A0A8T0IG37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G253000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000150">
        <property type="entry name" value="Alpha/beta fold hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46438:SF2">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="129"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="44445" checksum="B91216EAE97A23A1" modified="2022-10-12" version="1">MELQAAIRAVPSCWASSALASKSSSFVTVGVRGLGPLPALVAVRRHRSVSRKTWTPLVGELRVQRRAFVRDGVLAGAGLLVCAAAMAETAVQGGSSKTGLEQLPYKKDGYNFWTWRGHKVHYVVKGQGPPMVLIHGFGASAFHWRYNIPELAKTHTVYAMDLLGFGLSEKALIEYNADVWRDQVADFVREVVGKPAVLAGNSVGGYTILNAAAANPDLVSGLVLLNASGQFESSDQKLGEETPEKDVVEMEESLLKRIFITPIKDTVQKYSILFAFWQAKQPARIESVLRNVYKDQTNVDDYLVNSIVQPTSDPNAGEVYYRLMTQVLFKRSNQTINKLVTQISCPVLLLWGDLDPWMGPSKCDQFKKLYPKATIVRLQAGHCPHDEVPEQVNKALLDFANSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGK1</accession>
    <name>A0A8T0IGK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G270300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035828536" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6669" checksum="B47E4E2673160871" modified="2022-10-12" version="1">MLSVKFISFVVLGDCFLVCVSNSLQLLSHFQAFINVNASFLDLKFFVTRIRKRRITKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHF4</accession>
    <name>A0A8T0IHF4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">cytokinin dehydrogenase</fullName>
            <ecNumber evidence="3">1.5.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G017000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.99.12" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHF4"/>
    <dbReference type="OrthoDB" id="415825at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019139">
        <property type="term" value="F:cytokinin dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009690">
        <property type="term" value="P:cytokinin metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.462.10">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="entry name" value="Uridine Diphospho-n-acetylenolpyruvylglucosamine Reductase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016170">
        <property type="entry name" value="Cytok_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015345">
        <property type="entry name" value="Cytokinin_DH_FAD/cytokin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050432">
        <property type="entry name" value="FAD-linked_Oxidoreductases_BP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878:SF53">
        <property type="entry name" value="CYTOKININ DEHYDROGENASE 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13878">
        <property type="entry name" value="GULONOLACTONE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09265">
        <property type="entry name" value="Cytokin-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="FAD-binding/transporter-associated domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="FAD-linked oxidases, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="8">
        <location>
            <begin position="88"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0581883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="559" mass="62104" checksum="969370963A173929" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIC2</accession>
    <name>A0A8T0IIC2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G073300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIC2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15259" checksum="BEF9A59A8D5F49AA" modified="2022-10-12" version="1">MMSVTEWAYLGTSASGIRGYSCHDEPRCLHDRLCQAACSDPSSFPRELQDGSRVFRRKALNAREPTVGDPGERWICSVDVQDDSIVRGWARKSGGHSLSLRKMTSLQHVGTGRHVRFNEIKVQTHAQKYWKTAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJU2</accession>
    <name>A0A8T0IJU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycosylphosphatidylinositol anchor biosynthesis protein 11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G146100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJU2"/>
    <dbReference type="OrthoDB" id="17366at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009580">
        <property type="entry name" value="GPI_biosynthesis_protein_Pig-F"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06699">
        <property type="entry name" value="PIG-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0583552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="230" mass="24750" checksum="F6F7490CE113B718" modified="2022-10-12" version="1">MADQQKAEVQDDGFLSRDPGAIALLSLQGLCGVALVVGVKTVPAYYGLNLIAHPVAAIRCALALTLPTVVVAYTLLYIFSSRPRPVWRCIGSGLLSLPLGTVVIALLALAFGAPTSLQYASRTLHWAFLMSVLVVLPAAIVLGSSWPDWQRIFAFTRPRGGLERAICIPAHGALIGAWVGAFPMPLDWERPWQEWPISCTYGAAGGYLVGLTISILLQFLLPKDVRSKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK07</accession>
    <name>A0A8T0IK07_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G185700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK07"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45136">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45136:SF2">
        <property type="entry name" value="ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="29"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0584110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="156" mass="17701" checksum="333B57F47B7CCFB1" modified="2022-10-12" version="1">MAKGENDVFAALVQLQEAHQEAEAEIGAETAELKEKTVRNSSSFHKRSVSSSRKSFEESRLSTSKRDYSMNSNQGNATEKKAKMKPQIPSFRRLLALNRPEWRQALLGLTGAIAFGFVQPCYGFFLGDMMASFYDTDRSKLRHDIKIYARIFCGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILN5</accession>
    <name>A0A8T0ILN5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G140300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILN5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="17677" checksum="2AA63688B24FB54D" modified="2022-10-12" version="1">MLPARFRWWRSEYLFCDEAAQHVTTSLADLPLSMQESRLLESPCTLHPQSRLKTNRSSYAFPLICIYKQDIKCQLSMSRHLPGMPSKSQMSTGSLESLKAPSKPPRNDSPEVPQDNHWHDGSTGSCPQGPRDARDVVKWYFLFLKRNQILCLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMG1</accession>
    <name>A0A8T0IMG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G179500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="11"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="435" mass="49494" checksum="3ADD2B67322D004F" modified="2022-10-12" version="1">MAGPSLSLIHGVQQSNLPLEVMERVLSLLPLPVLCRMRTVCKEWNHIICSSSFHDCYEQTLEERGHGVCFLTRFVSSYPNKKIDRSVRGTTCFLDLEERRWYLIKGSVDQGFETKGVAMSDGLVAEICCPVPPKEGYNHGARTVCCIQMSDPILKMRWRLDPCPNESKLPYLVVVAADRGSRVFRVFEIDNPGFREIGFHRCLWIYESSTNKWRWASQKLGCLEANMLAIPHKIYPRSAVVFQQGLYAIFTAKLSLWRFLMLYDIEKDTWSMVLEDLPTAICEELVVSSGKLFMLFWRSASFCSSSSSMMLEMVEIQVSEKTLRSVFQIPASTLSHSCGGQISYYEWSDFTCLALRLNSDSSCSSVVLFSKSSGKVIIYNVVSATVDILPEHPLGKSDALNHEYWASHQNLYVRDILQKDAQSHPPVYMPKEQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMH9</accession>
    <name>A0A8T0IMH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G152300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMH9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="302" mass="33200" checksum="29B379FBDD3705EE" modified="2022-10-12" version="1">MRPTNVHGDVHGETSMRSRSQFNSPATLPVQAPETPPPRAYIDIDLAADSSWLPNPLTISLLEGPFVPDDDLAMMAPLDIPAPAPADPGPSTSSPDPAPGPSSAGPSTAHNDHHPLLNRENEEDRAYYLENPEDLPGVLNTIERNQRMWQTNILELGPEDYGAEYYGAEDYRAEDFRAEDYRAEDYGQEDLYGAEDCGEDSGDENQLHDQGQISKLGLANSTKFSGVDLVHDDESVGARLLNYSNEFEQLQDVKTSQQLDTKRNSSKSDNTQPEYVVCEILYSHFGMAAVSCVTMILVKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INN8</accession>
    <name>A0A8T0INN8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G181900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11635" checksum="23542BAF00B12EAD" modified="2022-10-12" version="1">MGSSYRTTRVHHGTRLDRALMRHQLPAPLQGVSWSRAPATLLQAHPRHRQARTTHRQARTHRQARTHRQARTTHRQAPTTLSHAPPSSSHGVAVRGNNPSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISA4</accession>
    <name>A0A8T0ISA4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G059100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISA4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12182" checksum="F397C040E6F0E8B3" modified="2022-10-12" version="1">MQYHFQMKNLNVNMGFTWPRRPLMLIATALSIERYNMPVISMHSSSTYAWQQGPQALGHLPCSLAPAFPEMHRIYPVHECPGLAQVQLRKAAQVTPRSSRREYLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISB5</accession>
    <name>A0A8T0ISB5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G103600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISB5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF160">
        <property type="entry name" value="HXXXD-TYPE ACYL-TRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="16553" checksum="6BC17A10A53D7879" modified="2022-10-12" version="1">MALVEYYPFAGRFTKGEDGRELVRCDDAGAFFTEVVVEETLDEIGGFEGCVMLSGMEAAGLTTTGLHSLDDHEEIPPLVIQVTSFKCKSIALAVNWYHLVCDGFSGMTFLKAWSELARGLPITSLPDHRRCHLFYRQTCCQYSSWGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISM5</accession>
    <name>A0A8T0ISM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">XRCC4 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G064800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032807">
        <property type="term" value="C:DNA ligase IV complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005958">
        <property type="term" value="C:DNA-dependent protein kinase-DNA ligase 4 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010165">
        <property type="term" value="P:response to X-ray"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010585">
        <property type="entry name" value="DNA_repair_prot_XRCC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014751">
        <property type="entry name" value="XRCC4-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053961">
        <property type="entry name" value="XRCC4_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28559">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28559:SF1">
        <property type="entry name" value="DNA REPAIR PROTEIN XRCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06632">
        <property type="entry name" value="XRCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58022">
        <property type="entry name" value="XRCC4, C-terminal oligomerization domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XRCC4 N-terminal" evidence="2">
        <location>
            <begin position="26"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="236"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="271"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="37757" checksum="3ECC0A07105EA9E3" modified="2022-10-12" version="1">MAEFDNKTCAKLEVQEGIEDGVKKLLFVKSEWNPTSFELAVSDGLRAWRFEGSEAIVNARAEAWDKGVSWVMEKLKFYLKVGQPGVAYRFTKTRDNQRKLSFDIEDKESELALTANFLMVNASDPESVTCDLLRFLHDSNARLTDSYLRKVQSLSQSFREQNALLEDDTKLKNAKTEIQNDYLKKFAAVLNSKKTKIREQQKEIERLKKENEKLREDSKSKAIDEDERDDTTSSSSEDEDDEEMSTPEKKVKRAEAFSERLVSEEKPFTEPASTSGVNVVNQDPEATQPFLEEVENDAPVSELPKEDPPSLPALIGDEPYKGIQRRRRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU94</accession>
    <name>A0A8T0IU94_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Legumain prodomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G111300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU94"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21115">
        <property type="entry name" value="legumain_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.130:FF:000001">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000005">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043577">
        <property type="entry name" value="AE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048501">
        <property type="entry name" value="Legum_prodom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046427">
        <property type="entry name" value="Legumain_prodom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000">
        <property type="entry name" value="HEMOGLOBINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000:SF42">
        <property type="entry name" value="LEGUMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20985">
        <property type="entry name" value="Legum_prodom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500139">
        <property type="entry name" value="AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035845644" description="Legumain prodomain domain-containing protein" evidence="9">
        <location>
            <begin position="22"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Legumain prodomain" evidence="10">
        <location>
            <begin position="377"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0586712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="53910" checksum="7C25B057D1775406" modified="2022-10-12" version="1">MGRVLGVVLLFFLGSVGVVSGWDGRIVMPTEERVKEPEPAEEGQRWAVLVAGSAGYGNYRHQADVCHAYQVLKKGGMKDENIVVFMYDDIAHNHINPRQGVIINHPDGADVYNGVPKDYTGKNVTVNNLFAVLLGDKEALKGGSGKVVNSGPNDHIFVYYSDHGGPGVLGMPTTPNLYADDLISTFKKMHEAKRYKEMVIYIEACESGSIFEGLLPEGLNIYATTAANAVESSWGTYCPGMFPAPPEEFDTCLGDLYSVAWMEDAEIENLKKETVRDQYLIVKSRTSNHNTYKTGSHVMEFGDLKINTEELDWYLGFDPANENVTGPIIPRENFANSLGDPKERHVNQRDADLIHYWHRYHKSKEGSTAKAEAGLDLTRAVSHRMHIDNSVELVGKLLFGVDAGPTILAAVRPRGLPLVDDWSCLKRMVRAFESSCGELTQYGMKHMRAFANICNAGVDSSKMGTVTAEACALSAFGSQTWKPLTTGFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUL5</accession>
    <name>A0A8T0IUL5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G120300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUL5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314:SF164">
        <property type="entry name" value="HTH MYB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="5">
        <location>
            <begin position="58"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0586822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="289" mass="32248" checksum="78AE29B046CDB3A4" modified="2022-10-12" version="1">MALGAKSTHVRSEVGNEMSRGTSTLPYPTKKRGVIPMTAEDSVAEFKRDRSNVRLYVRTSTQKLKWTRELHQSFMRAVNRLGGKDKATPKRILQHMDKDGITIAHIKSHLQMYRTGKINAEGLPSSATCSLDDHDPEQLKSNSKEFSSPHLQIPLKEAREVHMALQFLKEGRISGAAGTETLLKGLADIQAFKRIKTSDERMKQEDVKTHEFGLVPNAEPRPTSWSFFDEFRGIGNAVDVTDSLSGRKRKAEEDIELDLTMATRSASPRIQFPCPSTPEEATLSLGLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVX2</accession>
    <name>A0A8T0IVX2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">V-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G155300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVX2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd15873">
        <property type="entry name" value="R-SNARE_STXBP5_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042855">
        <property type="entry name" value="V_SNARE_CC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50892">
        <property type="entry name" value="V_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V-SNARE coiled-coil homology" evidence="3">
        <location>
            <begin position="166"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="30"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="51"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="137"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="152"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0587315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="25107" checksum="1C9B0E93A3FFD49B" modified="2022-10-12" version="1">MQDKVSIAATKEKVSNVAAKGGKAFMSLIHKAKHSVESPKSPKDLSESKSPEGSSELKSPEASSEPKSLEASSEPKSPRTLSAPKSPRNLSQLKPTGTFNETDGDSDELAASSPKTSMERKGKLVNRLKRGLKVGKKNTDAENRSELLDGNPNDQSPRIRSTDSIKAAYGHKPSTDPTSIAAQNREKLIERQEKLEAMNKDSEEMVEGAGDFASMAEELAKKIENKPWYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXD6</accession>
    <name>A0A8T0IXD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G196500</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12195">
        <property type="entry name" value="CIPK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14663">
        <property type="entry name" value="STKc_SnRK3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000279">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000096">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.80:FF:000002">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.80">
        <property type="entry name" value="Kinase associated domain 1, KA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018451">
        <property type="entry name" value="NAF/FISL_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004041">
        <property type="entry name" value="NAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895">
        <property type="entry name" value="CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43895:SF123">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03822">
        <property type="entry name" value="NAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50816">
        <property type="entry name" value="NAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 12" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="18"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="NAF" evidence="14">
        <location>
            <begin position="311"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0587855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="446" mass="50709" checksum="F31D7F451E91D327" modified="2022-10-12" version="1">MATKGITTNLERTRVGKYDLGKTLGEGTFAKVKMARHIETGMNVAIKILDKEKILKHKMVEQIKREISTMKLVKHPYVVQLLEVMASRTKIYIVLEYVTGGELFDKIARQGRLSEDEARKYFQQLIDAVDYCHSRQVYHRDLKPENLLLDAKGNLKISDFGLSALPQQFREDGLLHTTCGTPNYVAPEVIMDKGYSGATADLWSCGVILYVLMAGYLPFEEPTIMALYKKIYRAQFSWPTWFSSGARKLISKILDPNPRTRITAAQIYKNDWFKKGYTPAKFDREADVSFDDVDAIFSGSTEHMVTEKKETRPVTMNAFELISMSQGLNLSSLFETKEVPEKEDTRFTSKKSAKEIISTIEEAAKPLGFNVQKKDYKMKLQGDKLGRKGHLSVSTEVFEVAPSLFMVELQKNSGDTLEYNHFYKNLSKGLKDIVWKADPAEGVEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZ17</accession>
    <name>A0A8T0IZ17_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G206400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZ17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035792524" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="62" mass="7099" checksum="13B8755658BCD053" modified="2022-10-12" version="1">MVDFSACRAVCLVFFCLFRSSGKQELLNSRAQAPWQWPENRRTVSTNALLFKSSHFPFGFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J040</accession>
    <name>A0A8T0J040_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G236600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J040"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035760376" evidence="1">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6443" checksum="216DB72E8ACD42EE" modified="2022-10-12" version="1">MHSTTLGAVVVVSFVRVISTLKATQNATSNPEWNYSTDSEMEPVCNWHIKCKTAIWCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0F3</accession>
    <name>A0A8T0J0F3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G247100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0F3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11830" checksum="34D6486E713F0D53" modified="2022-10-12" version="1">MTLDDESEFKVVSEGGGTGYAMFYRMVLRSRWILRIAGLPVTLKHKRGICLRESPLIYNIVTCVAHRARLMRYSITTVIRASAVLLSTWNHYLTGTSNVLFSTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1L3</accession>
    <name>A0A8T0J1L3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G286200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1L3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9186" checksum="9933996A80CA4CA6" modified="2022-10-12" version="1">MEEDAALHQMQEAAQAVSNFHGKAKDVPDADAVMAMCKDWGVTADLKLHQAQGVSWLIGRYVQGVNVILGDEVRIPDCLDDMFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J213</accession>
    <name>A0A8T0J213_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G278500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J213"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="361" mass="39430" checksum="72040739C7E910BC" modified="2022-10-12" version="1">MFLKRTLTKHKFEFINLSTTVELKAQQYAEKALALHDQATSAGETAEAAWASIQSIVEKETKAEENVATAGATVLEAQENFTRAEKAFQVARWKLEPPGTSLDDLSLEIPETFLQQDDVESVDDRANGGASLETSEAEPSGDSKVESSEGDDNPPEESISKSKAAKEAGARKEYQLMESARVNFSDSEAALAQCEAELAQIQGTKMELQKEALRRSELSQAAKEAAALADEDVASAMILAEEAVALEVEAAQRVSDAEIALRKAEASAEEAAKAAVLAAAGTEKLANQVAESVSGTSVTSEPGKDEEESIIQRSRKKSLRRRRTRWWILNQKSPTQIQRVFWRLPPTRINRTNYLSLINTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4R0</accession>
    <name>A0A8T0J4R0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G074100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4R0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="entry name" value="B-lactam Antibiotic, Isopenicillin N Synthase, Chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050295">
        <property type="entry name" value="Plant_2OG-oxidoreductases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47991">
        <property type="entry name" value="OXOGLUTARATE/IRON-DEPENDENT DIOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="6">
        <location>
            <begin position="221"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="374" mass="41573" checksum="98D36A80F8EEFDB4" modified="2022-10-12" version="1">MGREVPRLAPGQELQSGNSIDTATKRPEEMLISIVESGIEQVPPEFIRPPHERVSRLDSDSQGPHEQIPVIDLSMMDDEGAGKRQVLAEIVRACEDWGCFHLINHGVPALVMDAAMKATKGFFALPASEREKYRMTKIGGKGYGQAYGGQTKDWNDRLFLTDFSGEEEPKSERGAFFDLVLTNPPGAQEALETYGEAVYKLVQRTMVLVSEALGQSPEFLSTEIPLRFGTITNHYPPCPQPDLVLGLLPHEDGGIFTFLHQDEVLGLEVLKDERWVPVPPIEHAFIFMVADLLQIVGNDRFKSVTHRVLAGPIARTVMANFAVTGNDAVIQPAPELCSDLEPPAFRSVVYKDYLKMLLRDDIHAKRLEAFRLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J522</accession>
    <name>A0A8T0J522_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G115300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J522"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF15">
        <property type="entry name" value="SLL1173 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="138"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="44748" checksum="A53F6EECFB9E727A" modified="2022-10-12" version="1">MMKYGVVVCLVLVVLCFGIAQYNNTCFLWRKGPWSRNASDLVNDPANEKQEPRPSTELSRLLKETVVHGRAGKVTIHLVKIMEEVKRPFFMFVCSNCYCDICEKVRDLGYLSPVKSMIFHYILRRSHMCKNGKGLVVDVGANVGYFSLISASYGCGVASFEPKSEAIRYLNLSRAINNYDNIHLHQQGVGQADTRAMYRRTDTSALKGSVERRRKLMSADSTLDVNGRLVEMESHPDSSMLNFQNLERRFSRRRILETADVTVLDSVIDGSVLLLNIDADGYEANILTGAKDLIHHRQVDHILVRVKQATSPAKRGLLWTLAKTGAYTHVYNWDEVVAPLSMPFHRFRLRNATIVDVTCIVHDQTSTAPLLYQDFWFSRQPLPWLRQFIDTIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5F5</accession>
    <name>A0A8T0J5F5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G068400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5F5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035724664" evidence="1">
        <location>
            <begin position="28"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11331" checksum="EBF8724157BC75F1" modified="2022-10-12" version="1">MNNFSMITMATLGNCTLILLLTPTASASFALHAPELHALPVPTHAKLDTPVKLSNWSNKHCEPGQCTSNTGTGNWQMTEGLVALYGSGTNRKLIIKTSCSVSGDGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7L5</accession>
    <name>A0A8T0J7L5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">KOW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G129800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7L5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000009">
        <property type="entry name" value="60S ribosomal protein L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_uL24_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_uL24_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="Ribosomal_uL24_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="134"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="205"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0590833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25595" checksum="29EDEFE03A85B161" modified="2022-10-12" version="1">MTLFRTQKLPLTPAAHATASAAIVAAAYRGRGNSSRRLPLGQVEVGETLKQGGTRQKLFRSHSQATPRWASLSSSVAAPPAPLPAAMKFSPRVSSSRRKSRKAHFSAPSSERRILMSAALSSDLKNKYNVRSVPVRKDDEVMVVRGTYKGREGKVVQVYRRKWVIHVERITREKVNGATVNVGIDTSKVVITKLKLDKDRKALLERKGKGRSAEKGKGKFTDADVAPPLQEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7T3</accession>
    <name>A0A8T0J7T3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Intraflagellar transport protein 122 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G185900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7T3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056152">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057411">
        <property type="entry name" value="TPR_IFT122"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF4">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23377">
        <property type="entry name" value="Beta-prop_IFT122_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25295">
        <property type="entry name" value="TPR_IFT122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT122 second beta-propeller" evidence="4">
        <location>
            <begin position="40"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Intraflagellar transport protein 122 homolog TPR" evidence="5">
        <location>
            <begin position="303"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="927"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0591585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1001" mass="113320" checksum="1D731498CD0EC2DA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7U8</accession>
    <name>A0A8T0J7U8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G130400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7U8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48017">
        <property type="entry name" value="OS05G0424000 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="9">
        <location>
            <begin position="42"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="14"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="51275" checksum="DE21E97BF2D91E84" modified="2022-10-12" version="1">MGESGVPTEAPHGVSSNGGTATANGSESGETTKVGLSSLWKGNSVFDAWLIAAAGQIGFVLVTMPYTMSQMGYAWGIAASVLYGLIGAWGVYLLVWLYLEFKSRIALQGKVRPENYIIQYHEVIGGLTGRWGRKITYFFIILTLFMVAIIHLVATSSNLYYANPRLNKREWTYIVGGVSFLAVLVPDFGHFRSGAFIGVITTTITSIYLLVAALSFGQRPGVKHTGANDKVEFFTGVANILSTYGGHGITIEILETMKRPSAYKYVNLAVFFYALLVTIPSSVAVYWSAGDILLKQSNAFSVLPRGGWQTLAIATIIAHQAMGFILFTHPIFLVCEKAAGVHTRRFFLRVLCRIPVVAIMFFFALAVPFFGPINSLLGSFGVAIGMYLIPAIAFLVTYRTKSARENSPVKPPWFLPTWSLVFVANVVVILWTLVVGVGLGGWAGISNLIRQIHTFGFFDKCFQCPPKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9C7</accession>
    <name>A0A8T0J9C7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Trafficking protein particle complex subunit 2-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G225500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAPP small subunits family. Sedlin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9C7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14854">
        <property type="entry name" value="TRAPPC2L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006722">
        <property type="entry name" value="Sedlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044760">
        <property type="entry name" value="TRAPPC2L"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12403">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04628">
        <property type="entry name" value="Sedlin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00024408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15973" checksum="06E549ACFD8FCF57" modified="2022-10-12" version="1">MIVCVAVVGHNNNPLYLQSFIDDDNTLKFHYIVHCSLDVIEEKVSNSKRAGVNLNETFLGLLYPTEDYKVYGYMSNTKIKFVLVTTDQDSRDADVRNFFRRLHAAYVDAASNPFHVPGKKITSAVFAERVGNIVKSFGAPAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA63</accession>
    <name>A0A8T0JA63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G188900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7598" checksum="F1D1723B08B50610" modified="2022-10-12" version="1">MLVQFLVVSHVVSCLLVISLPNHQEDFNSFKFHSSATTVPYRVTHCLLICISKKRPSFQQPLVSIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC33</accession>
    <name>A0A8T0JC33_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_1G286200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC33"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000415">
        <property type="entry name" value="receptor-like serine/threonine-protein kinase NCRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="189"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0592866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="59202" checksum="6291A906387A5F6E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7K6</accession>
    <name>A0A8T0G7K6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Chromatin modification-related protein MEAF6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G093400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7K6"/>
    <dbReference type="OrthoDB" id="440324at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000123">
        <property type="term" value="C:histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015418">
        <property type="entry name" value="Eaf6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13476">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09340">
        <property type="entry name" value="NuA4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="5 8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="88"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="14"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="133"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="148"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="160" mass="17591" checksum="BFF63F2638D1A355" modified="2022-10-12" version="1">MSGQRVTSNPHQTLNLLNARKEQLQEELRTVEKQLYDLETTYLHDSSQCGNVLKGFEGFLSSMKGSGNLKRPRKFQPEDRLFSLSSVTSPVVEESAGGRDADGKIDGSGPGRTKTNGFFGNGPGKQKRGRTAGPREGKRIKQVTDHGQEEDDDIDGLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G818</accession>
    <name>A0A8T0G818_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="7">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G147200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Secreted</location>
            <location evidence="7">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Secreted</location>
            <location evidence="7">Extracellular space</location>
            <location evidence="7">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="7"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G818"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02176">
        <property type="entry name" value="GH16_XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0052">Apoplast</keyword>
    <keyword evidence="7" id="KW-0134">Cell wall</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="1 7" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035967145" description="Xyloglucan endotransglucosylase/hydrolase" evidence="7">
        <location>
            <begin position="27"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="8">
        <location>
            <begin position="7"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <feature type="glycosylation site" description="N-linked (GlcNAc...) asparagine" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="33609" checksum="AF111EDD565DF197" modified="2022-10-12" version="1">MGLFRGAGYLAITTLVLLSLVAGSQAKLKDQFTTWTPNGCNYSADGRAVDLVLRSKNEPYASMTSKKSWMYGQIGAWIKLASGNSAGTVTTLYLSSTGNKHCEFDYEFLGNETGQPYLLHTNIFVDGVGGREQQIRLWFDPTLDYHYYNFQWNKDLLVFYVDNTPIRMFRNLEGTVTNFLYPKACPMKLYLSMWDGSKWATQGGRVKLDWNAAPFIASYKNFRLNGCEAMQDDKAAIHNCQNSTYAAPGEKFQRMGGTRTKQLREVKNNYVHYNYCDDRPRYPEMPEECKYNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G821</accession>
    <name>A0A8T0G821_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G166600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G821"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="57717" checksum="0F2E1DED57879E0A" modified="2022-10-12" version="1">MPKNKKQKNVGEWANKFDDMPSLHCRDYIVAFIVEFYQENTLVSLNSRYVRYEEDGPRKFKSEMETKIRDRLMDPCWHSDTQKPGYDHFVSQRAHDALWNAKEVITKYAKAQRGGVQAFKDTIAKADCFTRLMAPHSSRKHRRASITWWNSPIGMETAADLRKRHLTILADFAVFYYLDKEVQRGRYATIRRVRIEGNPQIPPYWEFAEKRPLNWSMRPDLARVDHNNESLAIRIPHPGVIRFQAIHQLEHVGFMFWWNGGTLRAMLQRDNEAPGDLPIDYIFRENADDSPILGKRLQLFRSKRTELAWALCNIIDAVHKYGYLHNDLSPDNILLHFPEDESKIYIGVCDWGLMTKTLENRRSPWVFENVHQKEETMRRRYWVDPRVVYVHKENQDIQIIPDLTVASEDFAAAKIAAKINRGNMCTAYHEAEPVETRHFQNIGELAMVFEGYLERVCQNNRGTIGGLGHLINRFRDTHNWPTPIEHYREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8A5</accession>
    <name>A0A8T0G8A5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_12G171700</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Vacuole</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8A5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010623">
        <property type="term" value="P:programmed cell death involved in cell development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.160:FF:000002">
        <property type="entry name" value="Cysteine protease 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000055">
        <property type="entry name" value="cysteine protease XCP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.160">
        <property type="entry name" value="Granulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000118">
        <property type="entry name" value="Granulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037277">
        <property type="entry name" value="Granulin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00396">
        <property type="entry name" value="Granulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00277">
        <property type="entry name" value="GRAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57277">
        <property type="entry name" value="Granulin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0926">Vacuole</keyword>
    <feature type="signal peptide" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035923481" evidence="14">
        <location>
            <begin position="27"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="17">
        <location>
            <begin position="50"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="16">
        <location>
            <begin position="135"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Granulins" evidence="15">
        <location>
            <begin position="376"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="357"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0555473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="468" mass="51525" checksum="CFBF5E4E3D91730C" modified="2022-10-12" version="1">MGWGGRVALGLALVLVFAAVAEQAQAGRANSIVGYDAHELHSEDALLDAFHAWLERHSKVYHSLAEKQRRFQIFKDNFVYIHNHNKQQKSYWLGLNKFSDLTHEEFRSQYLGTRPAGRANRVRSEANFIYEDVVADSKVDWREKGAVSEVKDQGSCGSCWAFSAIGSVEGVNKIVTGEMISLSEQELVDCDRGQNQGCNGGLMDYAFEFIIKNGGIDTEKDYPYKGSDGRCDEGRKQNSKVVVIDDYQDVPTQSESSLLKAVTKNPVSVAIEAGGRDFQHYQGGVFTGPCGTELDHGVLAVGYGTDDDGTNYWIVKNSWGPSWGEKGFIRMERLGSKDNDGKCGINIEPSFPIKKGPNPPPGPPSPPSPIKPPSQCDNSHSCPASSTCCCAFNIGKYCLQWGCCPMESATCCEDHYHCCPSDFPVCNLRAGQCLKSKSNPFGVPMLERTPAKFNWPKFTEESEGKASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8L9</accession>
    <name>A0A8T0G8L9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G166000</name>
        <name evidence="2" type="ORF">KC19_12G166300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8L9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="17193" checksum="12FE80F7323CF581" modified="2022-10-12" version="1">MLMPPRHNLNSKVPCKYRMMRLTALQCDGPALDMNWLTMLTAKARSGRVATMAYINEPTPALYGIPSISPSMASNSSNDSFINLTFTSSGVPMGLQSSMLNRLSTSLMYFLWHMVMVRALRFLSNATPRQYFNSPRSLIWNSPLSLALSHSNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8S1</accession>
    <name>A0A8T0G8S1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G091000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621">
        <property type="entry name" value="ASPARTIC/GLUTAMIC ACID-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33621:SF2">
        <property type="entry name" value="RIBOSOMAL L1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="336"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="647" mass="71151" checksum="AE19484397AF2577" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBK4</accession>
    <name>A0A8T0GBK4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">N6-adenine methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G108400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019369">
        <property type="entry name" value="Efm5/EEF1AKMT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041370">
        <property type="entry name" value="Mlase_EEF1AKMT1/ZCCHC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200">
        <property type="entry name" value="EEF1A LYSINE METHYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13200:SF1">
        <property type="entry name" value="NUCLEIC ACID BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10237">
        <property type="entry name" value="N6-adenineMlase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0554652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="190" mass="22334" checksum="1CE2A03E7E42F01D" modified="2022-10-12" version="1">METSNEPRTKRNRFLARTEEKWELNQYWYASNTIAMLTKEIEEHATKVAFLSTPSVWFSLENGDIKSRSYFFDVDLQWEKHPNFVHWNYNQPTEVDPKMHHEFDCVVIDPPFVTAEVWAKYAEAARLLLKDGGKIILSTIPENAVMLKEMLNVEPRAFQPSVPHLVYQYNFFTNYDSTNFASLNPEVESF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCH7</accession>
    <name>A0A8T0GCH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G079000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="9968" checksum="32C5B5AAD1D7818E" modified="2022-10-12" version="1">MLAEQALGVLHAGISQLARRERTTMAFLETVWELNSLMSTVTFSRGLPQRRRTTGVTFIFGVERECLLVGTFVCPFRKEKTKDCVSSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD67</accession>
    <name>A0A8T0GD67_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G055500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD67"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12217" checksum="2D8EF346A1795E8B" modified="2022-10-12" version="1">MEGPAFFSGLVRHRSGHERCQNHDQCSCSNCNIDTLFGSPMTTEDSSLKMVEPEMFSHTEGPSFVYFPDPSNGCGCDKWHCEKCRPRWTRDLHTAHFVISYFFDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGN1</accession>
    <name>A0A8T0GGN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G009600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035834688" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="6115" checksum="3A31FB51DF700CF2" modified="2022-10-12" version="1">MNFRAFAFLLGLLWRHVEVYSILDPFRNHGLPWISELISLSLQNWLTLALDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GH57</accession>
    <name>A0A8T0GH57_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Omega-hydroxypalmitate O-feruloyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G053400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GH57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF160">
        <property type="entry name" value="HXXXD-TYPE ACYL-TRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="512" mass="56339" checksum="537ADD4FFFAB971D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI58</accession>
    <name>A0A8T0GI58_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G082300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the alpha-ketoglutarate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI58"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02016">
        <property type="entry name" value="TPP_E1_OGDC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12470">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="entry name" value="Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1150">
        <property type="entry name" value="TPP helical domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="ODO-1/KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006914">
        <property type="entry name" value="PRK09404.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152:SF35">
        <property type="entry name" value="2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="EF-hand" evidence="5">
        <location>
            <begin position="760"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1056" mass="118435" checksum="FC6059387E87DDFE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIP0</accession>
    <name>A0A8T0GIP0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G094400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIP0"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF277">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE HT1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="193"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="471" mass="53097" checksum="98F828AD6B6FCF94" modified="2022-10-12" version="1">MAQLAFVYAMAKPRENREKVTIKEPVHDPKVTIKEAADDVTVGLGKVNVGGGRGFPHRFFSGNKTKTIPLGVHFTGPEKIQDAAELEKAEQKAKSRSLESSPEKDIPPARMKDDGGSAGNAGSHWLRKQKSIGTLMPRTNSMELPPSSKIKKVKFPDMKKSASWAHFVEVSQVEAPHLDMEVPEQYVCDMSALFLGQKFASGNHSRLYQGVYNDQDVAVKLLRLDNCEDAAIATRLERQFMQEMHCLSQLHHPNIVKFVAASWKPPVCCLIMEYVPGGSLRAFLRKLEKGSMPMKTILSMALDVALGMEYLHSQGVVHRDLKSENLVLTEDLHIKLTDFGVGCLETECDQRSADTGTYRWMAPEMISHKHYSKKVDVYSFGIVLWELVTGLLPFQNMTPVQVAYAVVNKNLRPTIPEDCPSSLRYLMEDCWLADPERRPNFYQIVQILEDLDKSWTEEPYHQQYAKSILFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJH6</accession>
    <name>A0A8T0GJH6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G024900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12300" checksum="29DCC30DBBB52583" modified="2022-10-12" version="1">MSMEILEIRGRVANAHKYLITALAWRKGECQRATLNALEARCNSMVLPHMGSKDTHACSASTVDEGSAGSTQNERRPCEACRQSRHAIAIGVSAECSPRCEAVSMLRRRHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK32</accession>
    <name>A0A8T0GK32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G134100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08267">
        <property type="entry name" value="MDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052733">
        <property type="entry name" value="Chloroplast_QOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44013:SF1">
        <property type="entry name" value="ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13602">
        <property type="entry name" value="ADH_zinc_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="1">
        <location>
            <begin position="15"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35521" checksum="32EC2F27D8B123E2" modified="2022-10-12" version="1">MAKMMQAAQYSKYHGGPSALEYVEVPVPTPKEGDMLVKVEASSVNIVDWRIQDGLLKHVLPRKFPHIPGTDISGEVVSVGPGVVGFAPGDKILSWIDLLRGGGFAEYALAPVTSTVKRPPTMTAVEAASLPVAAMTALQSAINLVGVKLDGSGPKLNILITGASGGVGLFWTQIAKLAGCFVTATCGARNMELVRSLGADEVLDYKTPHGAKYESPSGKKYDVVVHLAPYQPMEAFKPQLTKWGKVIDMTPTLRTVLRNWYNKITLSRQSFLPFVLDAKNTTFLQMVTDLVEEGKLKVIVDSTFPLSKARDAWARSIEGHSTGKIVLVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK60</accession>
    <name>A0A8T0GK60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FCP1 homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G005100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48469:SF1">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="3">
        <location>
            <begin position="1351"/>
            <end position="1549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="461"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="996"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1197"/>
            <end position="1263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="221"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1006"/>
            <end position="1018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1019"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1051"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1216"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1238"/>
            <end position="1252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1591" mass="178112" checksum="53ADEA87B7F825CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKU3</accession>
    <name>A0A8T0GKU3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G159800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKU3"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630">
        <property type="entry name" value="DIENELACTONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17630:SF44">
        <property type="entry name" value="PROTEIN AIM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="29"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25049" checksum="AC7E60C152858808" modified="2022-10-12" version="1">MVTEACCTPAPPAAPTQVGKEEVLAGTKVYITGSASASAAVIMINDVFGFDAPLLRKLADKVAVEGGYFVVVPDVLKGDPFTGSFAAGDFGPWIAKHGAKDEALEMTRGVVEAVKDKGFGAVGCAGFCWGAKVAVCLGKEKDVRAVVQLHPSFVEKSDYEEVVVPIAVLAAPTDGVEQYEELLASRTEVKSFVKVFSDVRHGWTVRYEENDENDVEKANEAHKLMLDWFAKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM03</accession>
    <name>A0A8T0GM03_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G149800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035748062" description="Secreted protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="53" mass="6364" checksum="F404E0E04A4E0790" modified="2022-10-12" version="1">MFSVRIPVMRLLCLCRAFFSLFCNLCQLRNWQCDFRDCSSFFAKLTQRAESFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMD0</accession>
    <name>A0A8T0GMD0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_10G123200</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMD0"/>
    <dbReference type="OrthoDB" id="1732493at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070985">
        <property type="term" value="C:transcription factor TFIIK complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004693">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008353">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07841">
        <property type="entry name" value="STKc_CDK7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000554">
        <property type="entry name" value="CMGC/CDK/CDK7 protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000097">
        <property type="entry name" value="Putative cyclin-dependent kinase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050108">
        <property type="entry name" value="CDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037770">
        <property type="entry name" value="CDK7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056">
        <property type="entry name" value="CELL DIVISION PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24056:SF0">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 15 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 17" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="21"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="14">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="27"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15 16">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR637770-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0559685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="37876" checksum="D136267124ED1538" modified="2022-10-12" version="1">MSGGASAGKMAMGDVTGVNRYEKGATIGSGTFGIVFKAIDKLTNRTVAVKMIRTGKYKEGVNVTALREIKLLKELFDPNVIELVDVYQHKRNLYLVFEYMESDLEAVIYDRNTFLSPADYKSYIQMTLKGLAFCHKKWILHRDMKPNNLLLGSDGQLKIADFGLARIFGSPDRRFTHEVFARWYRAPELLFGSKMYGPGVDVWAAGCIFAELILRRPLFQGTSDIDQLGKIFATFGTPREAQWPDMTALPNYVEYSYSPPQSFRSLFPQASEDCLDLLQRMFVYDPRQRISAQQALEHRYFRTEPAATPPHLLRRPVRHEGQTNALEPAPEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMU8</accession>
    <name>A0A8T0GMU8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ycf3-interacting protein 1, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G173900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048564">
        <property type="term" value="P:photosystem I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080183">
        <property type="term" value="P:response to photooxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040340">
        <property type="entry name" value="CEST/Y3IP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33672">
        <property type="entry name" value="YCF3-INTERACTING PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33672:SF3">
        <property type="entry name" value="YCF3-INTERACTING PROTEIN 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035730161" description="Ycf3-interacting protein 1, chloroplastic" evidence="3">
        <location>
            <begin position="18"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="297" mass="32667" checksum="A35EFDD504F48F37" modified="2022-10-12" version="1">MVGATLIGASMAGTAAAVGLTGTTCRCANAESILVSPVSAVRSSSGFTQVARQFAPRSYLNLQQGLRRGRKQESALCFQNVAGLWQRTSGSGRIMVKAMADESSESSVTTEDRTLSPQEEEDQANISEILRVVDLLKKKRDMTFNEVRLTIMIEDPREVERRRQLGIEDERGCSKEDMAVALQEVMDGKVPEDRLILRELTKEMLNWPNLEDEISGLNPLASPYAKMTPTGVDPKLAAQRAKVDWDAAAEIQPGEEPKDLSDMVPPVVGFSFLYFVSFIPVIIVVAVILILFFNSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMW2</accession>
    <name>A0A8T0GMW2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G021500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMW2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13906" checksum="0B2C31A9A1D29CDC" modified="2022-10-12" version="1">MDSQELDTMPLMSSQPTNSRRRSRDEEPPVPRRRRRIPSNRSLVIVFEVEPAFNGLPEGVFVGQFHNEDTEVHAWSEVEGVGHYRWLQGPMNHLPREQQLEFIADVMRQIFIFLRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNA9</accession>
    <name>A0A8T0GNA9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G033900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNA9"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47041">
        <property type="entry name" value="SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN / PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47041:SF2">
        <property type="entry name" value="SEC14 CYTOSOLIC FACTOR FAMILY PROTEIN _ PHOSPHOGLYCERIDE TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="CRAL-TRIO" evidence="3">
        <location>
            <begin position="233"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="403"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="53723" checksum="853A30B5479F21C6" modified="2022-10-12" version="1">MSGEMEENIVAEDEQAVVSYGNRGTRSSLPQELWRKSIAPVKSLKRVNLTNAAGQFLLFGAKVAALEAVRRISQARFRPLWWGLQGIFTIQAPPFNWLQRWSPFQHIAQATQSFSKPLVFLSIATAVASAIEEVRHATDESILDNLRALDDTPHHDHSDSEDSEEAILPTDQRALTMHLLKEELEDKGITLPERMDADELGRFLVAANGNVSNFISKVKKTVQWRERHHIFSATELKRWEHLVYWHGRDAQGRPTLIIRLGLAYTVLDPADHPGFAQAVVSQVEAGVLKLVVDKDDPTITVVMDCECENTVGFPLERLKSRIRLLQDHYPCRLASLLVVNLPPEMRGFAQEVLQILSPVTQKKVHLKGYRRYMGLLAVQLGPGENVPPFLGGRCKCQICSSKVISEEEQRRILERQAEARQRELEDAGRAMEIVSSRDPLSAEQSYTSTLRLLILGFVIIWIMVAMVAGHGSPKSPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNJ4</accession>
    <name>A0A8T0GNJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G096200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11865" checksum="B6131A179E4F18F9" modified="2022-10-12" version="1">MALSDSVPSSFVARRERQIFNVMAKEDCEDEGPNEAGGEGDEEHGGVTERLRQRTKRKPVYVEDDESMEDEEWEAPEEEEEEEEDDEDDEKDVRKGSRYDLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP46</accession>
    <name>A0A8T0GP46_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G165800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044183">
        <property type="term" value="F:protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034551">
        <property type="term" value="P:mitochondrial respiratory chain complex III assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20267">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045298">
        <property type="entry name" value="Complex1_LYR_LYRM7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050435">
        <property type="entry name" value="MZM1/LYRM7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46749:SF1">
        <property type="entry name" value="COMPLEX III ASSEMBLY FACTOR LYRM7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="4">
        <location>
            <begin position="8"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0560255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11324" checksum="AB5EC68F4F6CC1F1" modified="2022-10-12" version="1">MAGARSAEALSIFRALLRTRKQCFAGDPEMLVAAAKQIRDDFDEHRNVGPGEELDKLMTKAREAIKFMKANIIQAKQNDRGNYEVKLKPEHQGASIEEVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRI5</accession>
    <name>A0A8T0GRI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G169900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11246" checksum="334CEFD3054B4749" modified="2022-10-12" version="1">MCCNMTPSGMHSQTTKPLQTKPHQSHQHQHLQHHHSGTHQSLPQSSNTPSYSLFKPLPTAQDTTQNCKISPLQQPTLPPQFTPHPLQVSFIICPNVSFSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSI3</accession>
    <name>A0A8T0GSI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G072200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF1">
        <property type="entry name" value="OS02G0516800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="129"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="475" mass="52553" checksum="34340B9C8D835A8D" modified="2022-10-12" version="1">MARTDDEVEFQNDYEMPDDWNVLSFLQDNESCDKATIGNNMAPIFETATIDPSRSSTPNFTLSADHPHTALFTAQAVEGNTSNVTASLGQEHMVDDAEVKTPAEPVSQPKRSIARSNDKSAKPKRVRGPNWSEEEKNALLVLKLEALTRGPVIKCAGWSNDVSKNLLEKYGFDRNSKSCQQQWDTLLKDYKSIKKFHESTHSGISFWKMDEHQRSKSNEKFPQVFYKAWYVLMESIIEAEKAAKKTCSVKGTASIKGTATSIEVDANLPSPSIQVPSTTITINSADLIQLGQASDANYILSGPSQDQLVSTIVSTAAQFSNLATTDQSSQGHEDVVLDVSLRSTSQGNLQQSEDAEVSNMSNDDLISRIAPFVNKLIEDKLRHVLQSRQEEEQTYREKMLAIEKEKLALMHEKHNMLSTHHGATIMGSFASTSAYNQVVAPLNLASTSLAGQEDHIADDGSHGEVNLMQHYLRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUZ8</accession>
    <name>A0A8T0GUZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G173800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035801272" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8950" checksum="176163BCC520DE9F" modified="2022-10-12" version="1">MVWVTSRFRLLMLVVCCHWISASLSAEQHCANACTSLHSQVGIPLHPTSSFHSLALALALVRTCLPPNPTAKPKRVTSVRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX21</accession>
    <name>A0A8T0GX21_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_9G163300</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX21"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000178">
        <property type="entry name" value="serine/threonine-protein kinase PBS1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051824">
        <property type="entry name" value="LRR_Rcpt-Like_S/T_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48006:SF34">
        <property type="entry name" value="OS08G0203700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035865193" description="Protein kinase domain-containing protein" evidence="16">
        <location>
            <begin position="28"/>
            <end position="789"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="392"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="454"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0562664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="789" mass="87247" checksum="BA7BF570CE5D2026" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXX9</accession>
    <name>A0A8T0GXX9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-recycling factor, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Ribosome-releasing factor, chloroplastic</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G019600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Responsible for the release of ribosomes from messenger RNA at the termination of chloroplastic protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032544">
        <property type="term" value="P:plastid translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000001">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.20:FF:000017">
        <property type="entry name" value="Ribosome-recycling factor chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="entry name" value="Ribosome-recycling factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982:SF3">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOME RECYCLING FACTOR PSEUDO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="RIBOSOME RECYCLING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="Ribosome recycling factor, RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="9 11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Ribosome recycling factor" evidence="12">
        <location>
            <begin position="105"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="216"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0563295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="285" mass="31400" checksum="AFA50AB0BA6C1338" modified="2022-10-12" version="1">MSLCATVSVGPCMARMKEVMSPVQCSSPTYLCRAKAVGGGVALPQQLSSATVALRKCGVSSLKSLGRTIRQAVIRGATTEDVEAEKELIEMDAMERMEKALEATKSTFNTVRTGRASPNLLDRVQVEYYGTNVILKSIAQVSTPDGSTILISPFDKSSLTSIEKAIVKSDVGITPNNDGNVIRLNVPQLTADRRKELLKLVSKLTEDGKVAIRNVRRDAIKSYEKLEKERKLSEDNVKDLSDDIQKMTDDYIKKIETLFKQKEKVSVCFPNIDMHPSYCFSGSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY74</accession>
    <name>A0A8T0GY74_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G011100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY74"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007166">
        <property type="term" value="P:cell surface receptor signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.930.20">
        <property type="entry name" value="Adaptor protein Cbl, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036537">
        <property type="entry name" value="Adaptor_Cbl_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="234"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="554" mass="63254" checksum="130BFEF28C4905D3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1G9</accession>
    <name>A0A8T0H1G9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G122300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035881282" evidence="1">
        <location>
            <begin position="17"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="68" mass="7587" checksum="C15B0331E382E4F6" modified="2022-10-12" version="1">MYCRFLLHLCVHALQAASLLEPFRVAVTFEIGFLDSQNIQVLIILSVMSLICTIELLRGRLGSVCGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1I9</accession>
    <name>A0A8T0H1I9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G173600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1I9"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052138">
        <property type="entry name" value="GATA_ZnFinger_Domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47255">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR 22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47255:SF4">
        <property type="entry name" value="GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="6">
        <location>
            <begin position="187"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="64"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0565210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="348" mass="37887" checksum="CD83CA878B7EDD8D" modified="2022-10-12" version="1">MVGVVAIASPKEMEEEPSLCNLSLAVDCTLSLGSTLSRTVEAPASRLSRAGSPDPDLALSLSVRSERVDGSRRHTVEHDRSDQDMSWGSSCIRSDSDATPEYYPQVSERVARVGDGAKRSFKAWPRSSAQSYKDEVNTSKTLFGMIDDHKYSNRVSRQPWLSNYLPSSAVVEAKVASRVEQCMQEGDSFSRVCAHCGTSKTPLWRNGPGGPKSLCNACGIRFKKAGRRSAANGGSDSQVSPPVSTKVAKRKLVEDEQQYWLFPADAKPRKRSRGTAIRTSDSLLSGSCMTWQSSLLYSPKSPLQRDFPASPPSESEEKKELLEMGSFSSDEEEGAVLLMALSCGMVNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2E9</accession>
    <name>A0A8T0H2E9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G196000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum lumen</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2E9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005788">
        <property type="term" value="C:endoplasmic reticulum lumen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000005">
        <property type="entry name" value="Heat shock protein ssb1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0565510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="559" mass="63404" checksum="EF40303A1CC5653C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H623</accession>
    <name>A0A8T0H623_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-tyrosine-phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G016500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H623"/>
    <dbReference type="OrthoDB" id="10252009at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043622">
        <property type="term" value="P:cortical microtubule organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015275">
        <property type="entry name" value="Actin-fragmin_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035010">
        <property type="entry name" value="PHS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47100">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47100:SF5">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09192">
        <property type="entry name" value="Act-Frag_cataly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="775"/>
            <end position="922"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
        <location>
            <begin position="843"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="510"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="578"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="592"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="630"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="665"/>
            <end position="676"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="973" mass="107568" checksum="B9D06D097C032CE7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6A9</accession>
    <name>A0A8T0H6A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G015700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6A9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000344">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000031">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein mitochondrial"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000285">
        <property type="entry name" value="Pentatricopeptide repeat-containing protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24015:SF739">
        <property type="entry name" value="OS03G0644200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24015">
        <property type="entry name" value="OS07G0578800 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12854">
        <property type="entry name" value="PPR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="255"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="286"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="321"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="356"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="485"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="520"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="555"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="586"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="133"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0565809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="680" mass="76619" checksum="EF56CCA5CBB7930F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8P9</accession>
    <name>A0A8T0H8P9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione transferase</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G107900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Phi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8P9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03187">
        <property type="entry name" value="GST_C_Phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03053">
        <property type="entry name" value="GST_N_Phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000004">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000016">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034347">
        <property type="entry name" value="GST_Phi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900:SF3">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01154">
        <property type="entry name" value="Main.5:_Phi-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0567067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="215" mass="23843" checksum="FBC0DD8E419E8273" modified="2022-10-12" version="1">MTLIVHGAPYSTCTQRILATLVELNVEDYKIEFVDLRKGVHKSPDFLKLQPFGQIPVLQDGDITIFESRAIVRYLCEKFAGQGTPLLGKTVKDKALVSQWLEVESQNYNPAASLIVREKVFAPRMGAPSDESVVAAQTPKLEKTLDVYEAHLAKSKFLAGDFFSLADLSHLPYTNLLVNAAGKSDLISSRPHVSAWWNAISQRPAFQKVLAMAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H947</accession>
    <name>A0A8T0H947_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="10">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_7G093600</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="10"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H947"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1100.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="entry name" value="DNA-directed RNA polymerase, subunit 2, domain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1800.10">
        <property type="entry name" value="RNA polymerase alpha subunit dimerisation domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="entry name" value="RNA polymerase Rpb2, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007646">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007647">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04566">
        <property type="entry name" value="RNA_pol_Rpb2_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04567">
        <property type="entry name" value="RNA_pol_Rpb2_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RNA polymerase beta subunit protrusion" evidence="14">
        <location>
            <begin position="109"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="13">
        <location>
            <begin position="287"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="15">
        <location>
            <begin position="557"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="16">
        <location>
            <begin position="656"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="17">
        <location>
            <begin position="747"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="domain" description="DNA-directed RNA polymerase subunit 2 hybrid-binding" evidence="11">
        <location>
            <begin position="803"/>
            <end position="1164"/>
        </location>
    </feature>
    <feature type="domain" description="RNA polymerase Rpb2" evidence="12">
        <location>
            <begin position="1167"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF04566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0566864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1262" mass="141814" checksum="F1BEF1D9690A75AA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA02</accession>
    <name>A0A8T0HA02_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G006400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005254">
        <property type="term" value="F:chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044669">
        <property type="entry name" value="YneE/VCCN1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281">
        <property type="entry name" value="UPF0187 PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33281:SF19">
        <property type="entry name" value="VOLTAGE-DEPENDENT ANION CHANNEL-FORMING PROTEIN YNEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25539">
        <property type="entry name" value="Bestrophin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0568253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="362" mass="40952" checksum="3EA51F6F165C2186" modified="2022-10-12" version="1">MRGIATVYGHAEWAKHKSSWRHARHMKTILSSPVVVAIGPPAVVCTLIAVFVSVFNHEVSEGHLPHWVPLLHVAPLPFSLTSAVLSLLIVFRTNSSYNRYDEARRAWGSTTNRIRDLSRQVLSWIQKPADLHNLHCLLRHIKAFSYCLKDHMLEANLLREELLEVLNDPQEVDSILGSDHRPNYVLQLLAHILKQCHVSEWERLSMDRNITQFHDNVGACERIFKTPIPVAYTRLTSRVLFIWHIFLPFALIDSCGWLTAPATFLSAAALFYIEEVGVLIEEPFSILPLLAICDSNFSSIDGLLTAHLAIRKLFCTQPREPTACEDHVVVTVLEGSRSCTLDRAIREQDTGVNTFKRVNSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB31</accession>
    <name>A0A8T0HB31_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G056400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13132">
        <property type="entry name" value="MATE_eukaryotic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045069">
        <property type="entry name" value="MATE_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11206">
        <property type="entry name" value="MULTIDRUG RESISTANCE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="274"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="434"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0568981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="529" mass="57432" checksum="7C2A531A716A3435" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDK7</accession>
    <name>A0A8T0HDK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G042700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006527">
        <property type="entry name" value="F-box-assoc_dom_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017451">
        <property type="entry name" value="F-box-assoc_interact_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01640">
        <property type="entry name" value="F_box_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07734">
        <property type="entry name" value="FBA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="28"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="441" mass="51257" checksum="6A6C5CB236EE9785" modified="2022-10-12" version="1">MAEGYLDQMGKLGIGTATGVVAPDAEEAFLWKKLPRELQNRVLCCLPLQNLFQMRCVCKAWRNIVLHRDFATMYDAMHISDPSSPATVYINSSSPDRVEWSAYDYTQNKWQKRTTLPSRSHSRLTRENISYSVHPVGGLLVFRFWRLGVNHWVVWNPLTNKWKTLPPCKTRTSKTTVVFEHAFVADERFKRYKILMAHNPYSKDWRSFEQSTRNMVTEVYDSATGVWTQSESSLQSAVHPGFEYYYREEKYYPPDPPGVLSNGVIYFVSSSLRRDDSLESVLYCFDIKSERWHEEFRHGLPSWSITAIHGMTYDACKSVFEWDCRLMTAMVHPLDEEGGGRWELLVYERDLGTRTWVETGIKVPDSMVTTDSEFFTPEVEIVAEGNHLVLGEFRSRYGRFTCAVYRKAQNCWTCSPSGQFDVQDRKGNNLVLFKPRLDWRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEW6</accession>
    <name>A0A8T0HEW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G072400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02079">
        <property type="entry name" value="P-type_ATPase_HM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000022">
        <property type="entry name" value="Putative cadmium/zinc-transporting ATPase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051014">
        <property type="entry name" value="Cation_Transport_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01512">
        <property type="entry name" value="ATPase-IB2_Cd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085">
        <property type="entry name" value="CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48085:SF5">
        <property type="entry name" value="CADMIUM_ZINC-TRANSPORTING ATPASE HMA4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="396"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="562"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="589"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="912"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="261"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1317"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1317"/>
            <end position="1331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0569197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1408" mass="149318" checksum="6213E53034FDE051" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGJ5</accession>
    <name>A0A8T0HGJ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Triosephosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G115200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + NADP(+) + H2O = (2R)-3-phosphoglycerate + NADPH + 2 H(+)</text>
            <dbReference type="Rhea" id="RHEA:14669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGJ5"/>
    <dbReference type="OrthoDB" id="310895at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008886">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008911">
        <property type="term" value="F:lactaldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="entry name" value="Aldehyde Dehydrogenase, Chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051020">
        <property type="entry name" value="ALDH-related_metabolic_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42991">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42991:SF1">
        <property type="entry name" value="ALDEHYDE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="ALDH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldehyde dehydrogenase" evidence="9">
        <location>
            <begin position="46"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00040853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00042470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00042646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00043052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="12616" checksum="BA348B26F99C8D05" modified="2022-10-12" version="1">MIFPFGVDGAYHLVRTEVFFVTQDQVLDFRGMHLGCFSDAHVDKLIAASMVKEASLAQVKKLKVGNPFEEDTFIGPMNSEKDAERIEDWAKEAVEKGGKLLAGGGRKGAVIPAQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGW6</accession>
    <name>A0A8T0HGW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endoplasmic reticulum-Golgi intermediate compartment protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G176300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGW6"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF82">
        <property type="entry name" value="ENDOPLASMIC RETICULUM VESICLE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="7">
        <location>
            <begin position="10"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="6">
        <location>
            <begin position="152"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0570630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="43286" checksum="1A524A8CDD03184C" modified="2022-10-12" version="1">MAGRDLVQKLKQLDAYPKINEDFYSRTLSGGIITIISASFMVLLFFSELRLYLSPTIVNQLVVDTERGGTIRINLDVTFPALACSVVSLDAMDISGEQHLDVKHDIFKKRLDAHGKVIEPAKQDSVNQPTLEKPLQKHGGRLEHNETYCGSCFGAETEEDHCCNNCEEVREAYRKKGWALSNPDLIDQCKREGFLQKIKEEDGEGCNVYGTLEANKVAGNFHFAPGKSFQQANMHVHDLMAFGKESFNVSHKINEISFGVHFPGVVNPLDKVERTQIPMHGMYQYFIKVVPTVYTDVKGRKIISNQFAVTDHFKGGGPGEGHSLPGVFFFYDLSPIKVQFTEKTMSFFHFLTNVCAIVGGVFTVSGIIDAFLYYGHKQLKAKLGKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIC9</accession>
    <name>A0A8T0HIC9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G075600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DExH box helicase family. SKI2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000460">
        <property type="term" value="P:maturation of 5.8S rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18024">
        <property type="entry name" value="DEXHc_Mtr4-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18795">
        <property type="entry name" value="SF2_C_Ski2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000083">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000141">
        <property type="entry name" value="ATP-dependent RNA helicase DOB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.300:FF:000003">
        <property type="entry name" value="DEAD-box family ATP dependent helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1500.20:FF:000002">
        <property type="entry name" value="DEAD/DEAH box helicase, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3380.30:FF:000002">
        <property type="entry name" value="superkiller viralicidic activity 2-like 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3380.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025696">
        <property type="entry name" value="Beta-barrel_MTR4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048392">
        <property type="entry name" value="MTR4-like_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016438">
        <property type="entry name" value="SKI2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012961">
        <property type="entry name" value="Ski2/MTR4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF25">
        <property type="entry name" value="DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08148">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21408">
        <property type="entry name" value="MTR4-like_stalk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13234">
        <property type="entry name" value="MTR4_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005198">
        <property type="entry name" value="Antiviral_helicase_SKI2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01142">
        <property type="entry name" value="DSHCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="89"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="322"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="290"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="547"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00061045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1007" mass="113598" checksum="C729F4A4B6DD5C29" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKZ0</accession>
    <name>A0A8T0HKZ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG014100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="14074" checksum="1683AEC6ABCCEC22" modified="2022-10-12" version="1">MENNLLQLPSYSKRRGAPLSSWCLQRGDANGVKPSISSLAMSKNSRRSWRWLLRRFWDQCQQPQVPRLEKMNPSRGREVLDDHLVPLKHYRVQNSRRSPLSQTSTHGVRLDVKKLRILSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLR6</accession>
    <name>A0A8T0HLR6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG038200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLR6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="21564" checksum="EE24A20354C6E6B7" modified="2022-10-12" version="1">MMVDLPKVSLVSLILVFKSTTALRDLRLLLLRGNSTTHRDMRQDWRRARCLMQTWVQTWEDFLPITLSPGESVSPSASFTEMPLQELGVYNEEEDTGSWDFASVWANDQWKQTELTLRGSRDFTGPERGPRTSQVNPRTTFYNSSHVRRCLEFATRLTVVGFLTVDMLLKWTMMSRTSPTDELIGHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM29</accession>
    <name>A0A8T0HM29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG050800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33116:SF78">
        <property type="entry name" value="OS12G0587133 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33116">
        <property type="entry name" value="REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035869842" description="Reverse transcriptase domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="342" mass="38146" checksum="DEE7F091375C50BA" modified="2022-10-12" version="1">MLHMGFSSTWTNRVMTLYLLVANVLGHMLEDPKRGVISFMLPDGSRTTNLMFADDTNLLLKGTEANLDIAMQVLSTFCEATDAKLNESKLVAIWASRQPRDWTRTNDLGIVWLAEGANTKYLGSPIGFKMNPANRDRKVIIQLTKQLMISSPRKLSMTGRHLIVNQVLLASIWYLCSCASLTTSAFKQIRGIVRNYLWGAKLDKHTRAKVSWAIAVQLIAVGGLKVLDPAMQARALLTKLLDRGLSPEYAPWKTLVRHRVNQTRLMGGGKWTANAHFVMQPRAAPLASPPLWKAVHKAFSTIRQGLDQIPPTTFYEKLRQPIFANSLIKSSTGTPFGCKPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRS1</accession>
    <name>A0A8T0HRS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG198200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035859120" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="113" mass="12451" checksum="D837946177F4B9F8" modified="2022-10-12" version="1">MRRGARVVSKLSITPFVNSCCCLIWCGVSQSNRGSVWSEVKGDRLVAGGFFWRSEVEEYERYCCLVEVRSVTEVSVSGDGGVRCEGPGTLVRGCCRLDFNCVQLLENKSGSWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS82</accession>
    <name>A0A8T0HS82_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG192900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS82"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9470" checksum="93FB5CB6E2B06AE6" modified="2022-10-12" version="1">MTNLGIYWLGDGPRVHWSEAIKTFILDSLSTPAYEESESGKSSFTSGDDRRSVVFRIITLCCSRLHNGVMSLICGRYSFIYRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSG7</accession>
    <name>A0A8T0HSG7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_VG225200</name>
        <name evidence="10" type="ORF">KC19_VG225500</name>
    </gene>
    <organism evidence="9 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.210:FF:000009">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057444">
        <property type="entry name" value="Znf-CCCH_AtC3H23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF90">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25512">
        <property type="entry name" value="zf-CCCH_AtC3H23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="255"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="378"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="458"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="556"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="378"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="463"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="503"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="556"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0573960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0573963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="649" mass="69267" checksum="0D014A5F9290D304" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT29</accession>
    <name>A0A8T0HT29_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG227200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="10156" checksum="6173D11F34CC804F" modified="2022-10-12" version="1">MAKSLKVPKLSQNNEYGHDWGKYPRSEKRSMLYALQQSLKIVYPGSIYLTIISSKVKVVRSSTLVKKTFFERRSTPPNTHCPSTLRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV63</accession>
    <name>A0A8T0HV63_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG275000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV63"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16115" checksum="570ABA83AEA6FF60" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLHVLSPKRQSSTPKKRALYNNVVDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSDTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HW39</accession>
    <name>A0A8T0HW39_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG331600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HW39"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000320">
        <property type="entry name" value="Protein phosphatase 1 regulatory subunit pprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454">
        <property type="entry name" value="NISCHARIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15454:SF37">
        <property type="entry name" value="OUTER ARM DYNEIN LIGHT CHAIN 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="767"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="198"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="835"/>
            <end position="845"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0575264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="862" mass="93995" checksum="729D4258A32F37FF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWJ2</accession>
    <name>A0A8T0HWJ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG291300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWJ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035948272" evidence="1">
        <location>
            <begin position="39"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="12550" checksum="824A1414A5F1767B" modified="2022-10-12" version="1">MGASSNPTHGWVPSSHFALPLLLISRLLFLSLLPFSCPQQPRLPSASSLSTSPPCIHRWRLRIAPCSPASLLPCTHVAGIRASPLHYPPSTLIQFNSFIGFGTAILLKNMYIRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWU4</accession>
    <name>A0A8T0HWU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG321600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="10040" checksum="B2B9D9684DEB5549" modified="2022-10-12" version="1">MTKRFLSKVGKSLTRACAVTLPKVTEQVRAKVENGSNQNQHRRIRRHPVGSGYKFRIILQHRHIKMYRQRKTHHAVRLSLSNKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY88</accession>
    <name>A0A8T0HY88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G021200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY88"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005385">
        <property type="term" value="F:zinc ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040:SF210">
        <property type="entry name" value="ZINC-REGULATED TRANSPORTER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11040">
        <property type="entry name" value="ZINC/IRON TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0575659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="31058" checksum="8441F5F6F493B8D8" modified="2022-10-12" version="1">MNSAIEDEVVSFGSQVWVALALTMVGGLSTALGGLVVVLQPTPNLKRLGILQGLAAGLMFTISFNDLMHNAINAIGFPRANLWFFGGVMMFAGIVTLIPEPSLTPAQNAAMDAVGKGKKGGKEGKETAHLMRQRRKQVLMSGIVTAIGIGLHNFPEGIAVFLGSIKGLRVGISLACAIALHNIPEGVAVALPVYFATESRWKAFQLAAFSGLAEPLGVVLVATLFPQSMPHHILEGLLAGVGGIMAFLTLHEMVPLALEYAGRRQAIASVFIGMALMSVSLYLLEISVPQDIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0P5</accession>
    <name>A0A8T0I0P5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PROP1-like PPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G126900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0P5"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033443">
        <property type="entry name" value="PROP1-like_PPR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17177">
        <property type="entry name" value="PPR_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="187"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="257"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="327"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="507"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="PROP1-like PPR" evidence="5">
        <location>
            <begin position="522"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="542"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="577"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="612"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="706" mass="79963" checksum="DBFD6BE226147A94" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I214</accession>
    <name>A0A8T0I214_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G135800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I214"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7950" checksum="6E4D0885B767AFA0" modified="2022-10-12" version="1">MNSPCIPLTSNRHCAYNRHYLPKQSAQLRNSTCRCKLVGTVPTFQNFSVIVYGYGRLSKSVRLSATSKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3Z6</accession>
    <name>A0A8T0I3Z6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G009100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3Z6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372">
        <property type="entry name" value="DAUER UP-REGULATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47372:SF11">
        <property type="entry name" value="RE19971P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="229"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="277" mass="29626" checksum="C291A8F1A77523C1" modified="2022-10-12" version="1">MNESSFPSLNIIIVVVVHCSICTIDHRLLQRLTFCRQLPKLQLIRHPKSRICASGRMGSSSSPTTHSLQKCQGMQQFSFGDPHGSSRASQVSALLRQVAHFGATHVVTSVLFLSHKTTSPLIICISTAISFALSHSQNSYHFLVFIFGTHLARLRTPLDNMSNFDATKDSAAQKAEETKGFGQQKAGEAHQATMDAAGATQDKAQDAAGTAQDKANQAGGMAGEKWEQTKQASSDATQAAQDKAMAAKDGAGNMLQQAQNAVGNAFNQAKDAVTPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6R4</accession>
    <name>A0A8T0I6R4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Complex III subunit VI</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Mitochondrial hinge protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_4G049300</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UQCRH/QCR6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6R4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006122">
        <property type="term" value="P:mitochondrial electron transport, ubiquinol to cytochrome c"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.20:FF:000001">
        <property type="entry name" value="Cytochrome b-c1 complex subunit 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.20">
        <property type="entry name" value="Ubiquinol-cytochrome C reductase hinge domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003422">
        <property type="entry name" value="Cyt_b-c1_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023184">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036811">
        <property type="entry name" value="Ubol_cytC_Rdtase_hinge_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336:SF0">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15336">
        <property type="entry name" value="UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 7.8 KDA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02320">
        <property type="entry name" value="UCR_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81531">
        <property type="entry name" value="Non-heme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Ubiquinol-cytochrome C reductase hinge" evidence="13">
        <location>
            <begin position="68"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="15"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="67"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00044364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00076110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0578787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14757" checksum="4889E86A2137A0EC" modified="2022-10-12" version="1">MVKWWCATGLVCRAAEAEEQHQEAPQEEVAEEKAEETPSEEEAPVEEEEDAPAEEEEEEEEEEEEVHDPKPELESSCKPKCVKQLLALQACEKRVEEDEGGEKHCTGQYFDYWGCVDKCAAPKVFRKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7P6</accession>
    <name>A0A8T0I7P6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G071000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7P6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8637" checksum="EFE79B6D195DEC39" modified="2022-10-12" version="1">MVQPIIKMSIGKPVYGNLERFTAPAFHQRKPLMELEVSDPLTFHTISSRMILLMSFVQFCTRTLHSQLCICRAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8B0</accession>
    <name>A0A8T0I8B0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Dynein axonemal assembly factor 11-like CS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G044900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tilB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8B0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000052">
        <property type="entry name" value="Leucine rich repeat containing 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056496">
        <property type="entry name" value="CS_DNAAF11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849:SF0">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18849">
        <property type="entry name" value="LEUCINE RICH REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23602">
        <property type="entry name" value="CS_DNAAF11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14580">
        <property type="entry name" value="LRR_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0966">Cell projection</keyword>
    <keyword evidence="6" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Dynein axonemal assembly factor 11-like CS" evidence="10">
        <location>
            <begin position="210"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="177"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="371"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="182"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0578718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="415" mass="47774" checksum="9B2CF938FB113BFD" modified="2022-10-12" version="1">MGGDITQEMIRRRSEHNECVLYTMEELVLQEESIERINKTLGILCPHLKILYMPNNLIPRLENLHKLKELEYLNMAMNNIIKVQGLEKCEQLKKLDLTLNFIDLQNLPSVTSLNANVHLRELFLTGNPCTDWDGCRSYVIAKLPHLKRLDAWEIKPRERITALQEIHRLEEDLQAMNSSEEPIVKETQVEKDEKGELKRMYTPDTRIAEHRELKELREQEEKKSERPDSQRKESTRRKGFDPLPVNGRVYQKNEGGWEIKLDESDCGTKIILDVAISKFLDTSLIDIDVQPLLIRVLIKGKLLQLHLPTEVKTDASSAERSLTTGHLVVTMPLVTPSVAFKPKHFPDYYVTGQPKVEASPPQTQVVNIHNITNKEEPPKEPSKHNPRTNCTYPAKSEPEGKQQPPSWTDDVPQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA25</accession>
    <name>A0A8T0IA25_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G128100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF9">
        <property type="entry name" value="PROTEIN DETOXIFICATION 46, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="585"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="619"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="653"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="52"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="724" mass="77182" checksum="72D90E9DB62F9252" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAF5</accession>
    <name>A0A8T0IAF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G193900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013187">
        <property type="entry name" value="F-box-assoc_dom_typ3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF12">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08268">
        <property type="entry name" value="FBA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="33"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="445" mass="50943" checksum="C4E13A378897DD61" modified="2022-10-12" version="1">MSDEETLYDFNTNNSNVLELDNRFIEEDNRELDSRWGSLPDDLIDRILAWLPLPSFFGFRSVCRRWNDILYSPSFYQLCSCVPQTIPWLIISAYESCKTSATYDPLTNRWYMYKFPTNICCGGKNNNNNNLSHPIAAADGLLCSSMFQDGSEYLLICNPMTRACTKPVPIPVNCDNVLAGMIVDKKTRTYQVILAECKSYSRTNIEVSSVSSSSSSDTELEEAEYCEVCTFIYDSRKPSTWRNGANFVIEGHLDVGSATCNNILYFITHGAYKPNGLIAYDVTYNRWRRINVTMPRLLLYAYLVDHHGHLLMIGGLGKFSVTTKIWIWKLDTSDDDWVLIGKLPPKLFKEFFSMTPSKYFMCAGQGNLLYLCAYKSTKCLVYNIYQKNWHFLPPCPLLVKYPSVTPSGFCFEPRLDGSVLGKFQPDPKSICINNSFRNCMKWKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBD6</accession>
    <name>A0A8T0IBD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G158300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBD6"/>
    <dbReference type="OrthoDB" id="9421954at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00074">
        <property type="entry name" value="HFD_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000009">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007125">
        <property type="entry name" value="H2A/H2B/H3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032454">
        <property type="entry name" value="Histone_H2A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032458">
        <property type="entry name" value="Histone_H2A_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00125">
        <property type="entry name" value="Histone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16211">
        <property type="entry name" value="Histone_H2A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00046">
        <property type="entry name" value="HISTONE_H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0158">Chromosome</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core Histone H2A/H2B/H3" evidence="9">
        <location>
            <begin position="8"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Histone H2A C-terminal" evidence="10">
        <location>
            <begin position="89"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF16211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0580226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="13887" checksum="4FD5656768F14DFF" modified="2022-10-12" version="1">MSGRGKSSGKKTVSRSSKAGLQFPVGRIARFLKAGKYATRVGAGAPVYLAAVLEYLAAEVLELAGNASRDNKKTRIVPRHIQLAVRNDEELSRLLGQVTIANGGVLPNIHTVLLPKKTGTTAGGKPGKAGSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBV9</accession>
    <name>A0A8T0IBV9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PPPDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G233900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DeSI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070646">
        <property type="term" value="P:protein modification by small protein removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1720.30">
        <property type="entry name" value="PPPDE domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008580">
        <property type="entry name" value="PPPDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042266">
        <property type="entry name" value="PPPDE_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12378:SF7">
        <property type="entry name" value="DESUMOYLATING ISOPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05903">
        <property type="entry name" value="Peptidase_C97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01179">
        <property type="entry name" value="DUF862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51858">
        <property type="entry name" value="PPPDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPPDE" evidence="5">
        <location>
            <begin position="28"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="261" mass="28678" checksum="538CA1CF1321906E" modified="2022-10-12" version="1">MCKSLLNHLIRLKSCKVSKNQRMEEEGEKVFLYIYDLSQGMAREITTNFLGNTIEGVWHSGIGLFGKEYFYGAGIQCVPIGRSPFGAPVEVLELGITHIPKDIFEEFLREIGPRYTVATYSLLNHNCNNFTDEAAQFLVGSGIPHHILRQTDLALNNPLGALMLPMLQQLETTLLHGGILMTPRNSFGGSSVHPIPTTPRSTSEVSATRESVSTFPAPFPPSTNRVAPTINSTTPTSPRRSDQNMTNNSDIGAGTENSKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC29</accession>
    <name>A0A8T0IC29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G177500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1357022at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF385">
        <property type="entry name" value="DISEASE RESISTANCE PROTEIN (TIR-NBS-LRR CLASS)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14559">
        <property type="entry name" value="TPR_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="18"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="1155"/>
            <end position="1188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0580497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1314" mass="147748" checksum="F1132EECD7439051" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDS8</accession>
    <name>A0A8T0IDS8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G018000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDS8"/>
    <dbReference type="OrthoDB" id="5585087at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005736">
        <property type="term" value="C:RNA polymerase I complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005665">
        <property type="term" value="C:RNA polymerase II, core complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005666">
        <property type="term" value="C:RNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.28.30:FF:000002">
        <property type="entry name" value="DNA-directed RNA polymerases II, IV and V subunit 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.30">
        <property type="entry name" value="RNA polymerase ii, chain L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006591">
        <property type="entry name" value="RNAP_P/RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039747">
        <property type="entry name" value="RPABC4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASES I, II, AND III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12056:SF2">
        <property type="entry name" value="GEO11084P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03604">
        <property type="entry name" value="Zn_ribbon_RPAB4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00659">
        <property type="entry name" value="RPOLCX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="RNA polymerase subunits"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0581894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6247" checksum="28E61CDDD85C06F8" modified="2022-10-12" version="1">MDGGMGAPPPEPVTYLCGDCGADNTLKPGDVIQCRECGYRILYKKRTRRIVQFEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE64</accession>
    <name>A0A8T0IE64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G230200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37244">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37244:SF1">
        <property type="entry name" value="NADP-SPECIFIC GLUTAMATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="36885" checksum="6455D90B3951F77A" modified="2022-10-12" version="1">MASLPKVMSSHKSAAQADQVSCFDASMLYIRVTNCQPTPGIPESLIMHFLPRDKSVCLEVNGARIPSSEEVSLVLRCSRNLKNNTDPPADFMYVSTDSICTSSTLQFQILDQADSGNLIISGYLEKKMPDDSAITPKAQWIMGSNCEISSDGCAFVKRKHELSKHQGVDVSIPSVAGTAMEMGVVGRCMGKPMILTQTVSLKCRHNLSSYDILNDMPDDNEVGKPADGVAATMRMTSLDFFDKGGEVAFFDIPRSSHADSTSKALAKAAGFESKVMIVKFDSSSLSMTNTDQEKWYNRGISTGIKLGLGFGIGMCIGVGIGLGLIIHKFRTTTNSLKRITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IER1</accession>
    <name>A0A8T0IER1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="5">2.4.1.143</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="21">Beta-1,2-N-acetylglucosaminyltransferase II</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">GlcNAc-T II</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="19">Mannoside acetylglucosaminyltransferase 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="18">N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">KC19_4G216400</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="22">
            <text>an N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;3)-[beta-D-GlcNAc-(1-&gt;2)-alpha-D-Man-(1-&gt;6)]-beta-D-Man-(1-&gt;4)-beta-D-GlcNAc-(1-&gt;4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12941"/>
            <dbReference type="Rhea" id="RHEA-COMP:13526"/>
            <dbReference type="Rhea" id="RHEA-COMP:14369"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:60615"/>
            <dbReference type="ChEBI" id="CHEBI:60651"/>
            <dbReference type="EC" id="2.4.1.143"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 24">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glycosyltransferase 16 (GT16) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.143" evidence="5"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IER1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005795">
        <property type="term" value="C:Golgi stack"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008455">
        <property type="term" value="F:alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009312">
        <property type="term" value="P:oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006487">
        <property type="term" value="P:protein N-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007754">
        <property type="entry name" value="GlcNAc_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12871:SF0">
        <property type="entry name" value="ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12871">
        <property type="entry name" value="BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05060">
        <property type="entry name" value="MGAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 25" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="16" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="17 24" id="KW-0464">Manganese</keyword>
    <keyword evidence="14 26" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 24" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="28" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 26" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 26" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="26">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="binding site" evidence="23">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="24">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="25">
        <location>
            <begin position="185"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="25">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="25">
        <location>
            <begin position="318"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00014817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00029663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00032552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00032915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00093257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PIRSR" id="PIRSR607754-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PIRSR" id="PIRSR607754-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="PIRSR" id="PIRSR607754-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="26">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAG0580993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="49859" checksum="765AD2ABA81077AB" modified="2022-10-12" version="1">MGLFSSKRGAAASSCGGRQLWILLLLQIMVLVFVVGPYLAATEEFNGWLEGGNLRRPAGSPVVDPEALRLRGVNLPELNELAKQLLVRNSLPPRNRDLFPALSDDRVVIVLYVHSRPKYLELVVSSLAEVRGINETLLIVSHDGFYEEMNTIVESIRFCQVKQIFAPWSPHLYTDQFPGFTPGDCQSKDDADRLGCKGNADQYGNHRSVRIVSLKHHWWWMMNTVWDGLEETKGFNGHMMFIEEDHYMLPNAYRNIQILAKLKQEKCPDCIAVNAAPFDVKSRGEGFSKLVAEKVGNVGYTFNRTVWERIHDKAESFCTFDDYNWDITMWATIYPTFGSARYTLRGPRTSAVHFGRCGLHQGYSKSRSTECRDSSMRLGIIDEGDKVPNIDPRWPVHTFPIKGYSSGFRGWGGWGDKRDQQLCFAYSSMYSNPIIPTDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFF1</accession>
    <name>A0A8T0IFF1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G034400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFF1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="131"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="415" mass="47253" checksum="08DE02BC0D44E9CE" modified="2022-10-12" version="1">MESTEGIGEKWKQIDLDLDDYTNYNDEIKQLCDRCSGVRSTGPCSGKEKGKCCCNPNGLPSPLCVYYSPRIMGLLNGEKTEFDTAREHWTALDPEGEAEAEKIADENRKYFDEVLAKHPEWGAFFTRIQHLEVGDKIGEGAQAEIFAISSSPRIVDVREEVELVAKVWKAGVSLKHLERQWPPQVMSQLSQETKEYPFTNIYGGIFIREGEFKNRFAFVMKRYVCDLRTYIDQHQMLEMLHKKNHGPPLKHIQAVYEVMLEVAIDLEILHEAGVVHRDIKASNVLKGDDETYLSPGSFLIDYECSVGVVGTRFWRAPEILEQLQKGVCGCDMVFTKKADIYSFGMMCYEVVTGCIPFEGHPHNDYSIVISGERPPLPDDMNSELRSMIVECWHQEPLSRPNASTLREKLYTLYGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGY1</accession>
    <name>A0A8T0IGY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tyrosine-specific transport protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G072000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015173">
        <property type="term" value="F:aromatic amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003333">
        <property type="term" value="P:amino acid transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1740.10">
        <property type="entry name" value="Amino acid/polyamine transporter I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018227">
        <property type="entry name" value="Amino_acid_transport_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013059">
        <property type="entry name" value="Trp_tyr_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195">
        <property type="entry name" value="OS07G0662800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32195:SF26">
        <property type="entry name" value="TRYPTOPHAN OR TYROSINE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03222">
        <property type="entry name" value="Trp_Tyr_perm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00166">
        <property type="entry name" value="AROAAPRMEASE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="186"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="437"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0582592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="500" mass="52493" checksum="BB4CA00ACEC5E788" modified="2022-10-12" version="1">MEAVAIALPSQLGCHGRRCDGVGIFRSRSAVRGARFGVNVRRGGSVVVVRSKQPDVEQEKEELSSGFDMPTRGGMKLERKLEFGEDRRVERMFSNLNEVSLKHEPGSLLNAVLLIAGTTVGAGILAIPSVTQESGFLASSVACIGCWLYMVGSGLLVAEVNVNTMCELGSGGVSLVSMALRTLGDWGVRVACGAYLFIHYALLVAYIARSSDIVTNAVGTPLWVSAALFTGSLGGLCYFGSQRVIGLVNGGLVVGILGSFGLLVTVGSAGLDFNSLLRANWEAVPHSIPVIALAFVYQNVVPVVSTSLEGDLPKIRTAVVLGTGIPLVLFLIWNAVILGTSSSLVDGSGVVQAISDPLLRLRSASGIVGPTVEIFSLLAVATSFIGFVLGLSDFLCDLFKLPGGGRRSPLPYILTLLPPFFLSQTSPEIFYQALDFAGTYGVLVLFGILPAAMAWSERYSGTCLPPSTKPIVPGGRVTLAFFIGAAGFVITSEAISKLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHE6</accession>
    <name>A0A8T0IHE6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G118400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotransferase class V" evidence="3">
        <location>
            <begin position="227"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="19"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="66"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="583" mass="63187" checksum="4BAF9168B16C7946" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHZ9</accession>
    <name>A0A8T0IHZ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Zinc finger PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G068400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd15565">
        <property type="entry name" value="PHD2_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15566">
        <property type="entry name" value="PHD3_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055198">
        <property type="entry name" value="NSD_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055197">
        <property type="entry name" value="PHDvar_NSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46235:SF3">
        <property type="entry name" value="PHD FINGER-CONTAINING PROTEIN DDB_G0268158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22908">
        <property type="entry name" value="PHD_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23004">
        <property type="entry name" value="PHDvar_NSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="7">
        <location>
            <begin position="347"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="7">
        <location>
            <begin position="410"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="Zinc finger PHD-type" evidence="7">
        <location>
            <begin position="480"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="304"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="584" mass="65112" checksum="25A8EAFA3F5A3B9E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IID8</accession>
    <name>A0A8T0IID8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DEX1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G044000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IID8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056376">
        <property type="entry name" value="DEX1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045232">
        <property type="entry name" value="FAM234"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21419:SF23">
        <property type="entry name" value="PROTEIN DEFECTIVE IN EXINE FORMATION 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23722">
        <property type="entry name" value="Beta-sand_DEX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="Integrin alpha N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035884315" description="DEX1 C-terminal domain-containing protein" evidence="7">
        <location>
            <begin position="21"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="domain" description="DEX1 C-terminal" evidence="8">
        <location>
            <begin position="670"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="236"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="237"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="255"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="814" mass="89651" checksum="3CE4914F897E0E57" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJQ6</accession>
    <name>A0A8T0IJQ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G143600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJQ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF1">
        <property type="entry name" value="RAS SUPPRESSOR PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="4">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="41519" checksum="0826E5218268B3F7" modified="2022-10-12" version="1">MDKGGDAISLTIKFGVTNIAISLPASSKVSDLMHQLQSATDILPRVQKLIFKGKVLTPDLTLKNAQLKDGSKIMLMAAQGFQSRFPVRSASPVKRKTSPPKSSITSKQIPLKPTEVEESRLKAWKLTGVVSLRDSGSQKVPAAVWSLQSAVRVLDLAGNCLSAFPSDIKGLTNLQRLRLWGNQLKSDSIDWKSLASLSQLSVLALDHNLLDTIPPEIGQLTSLKYFTASNNKLASIPEEIGNLRVLEKLDLSYNCLRDVPAGIGRCAQLSEINLTGNLLISIPASWSQMMFLKKLLLDSNQLKDFPPAILQKCAQLQTLSLHSNELTMDDLRELEGWSEFDKRRKDKYTKQIDMQVMGSTSGFDEGADTEQWQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INA4</accession>
    <name>A0A8T0INA4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">sulfate adenylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_3G172200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>sulfate + ATP + H(+) = adenosine 5'-phosphosulfate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:18133"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16189"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="EC" id="2.7.7.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the sulfate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INA4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00517">
        <property type="entry name" value="ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.400.10:FF:000002">
        <property type="entry name" value="ATP sulfurylase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000006">
        <property type="entry name" value="bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.400.10">
        <property type="entry name" value="Sulfate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025980">
        <property type="entry name" value="ATP-Sase_PUA-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024951">
        <property type="entry name" value="Sulfurylase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002650">
        <property type="entry name" value="Sulphate_adenylyltransferase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00339">
        <property type="entry name" value="sopT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055:SF37">
        <property type="entry name" value="ATP SULFURYLASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11055">
        <property type="entry name" value="BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01747">
        <property type="entry name" value="ATP-sulfurylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14306">
        <property type="entry name" value="PUA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="ATP-sulfurylase PUA-like" evidence="14">
        <location>
            <begin position="85"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Sulphate adenylyltransferase catalytic" evidence="13">
        <location>
            <begin position="257"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF14306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0583923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="53690" checksum="D90E71418DA163CE" modified="2022-10-12" version="1">MEAVLGRVSLVAATGSRSVVVGDSKVKSGTGWFSGGSVVVLPVTAKLQRRERLYRSVAAKLATDNASASTSATMDAAVPRTGGLIEPDGGVLVDLHVPEQEKESKRAEAATLPRIQLAKVDLEWVHTVAEGWASPLTGFMRQSEYLQALHFNCLRLPDGSFVNMSLPIVLSIDDEKKESLAGVTAVTLVGPDGNDVAILRNIEIYKHNKEERIARTWGTTASGLPYVDEAIANAGNWLVGGDLEVLERIKYNDGLDHYRLSPAELRAEFERREADAVFAFQLRNPVHNGHALLMTDTRRRLLDMGYKNPILLLHPLGGYTKADDVPLEWRMKQHDEVLEAGVLDPATTVVAIFPSPMHYAGPTEVQWHAKARINAGADFYIVGRDPAGMGHPTAGRDLYDADHGKMVLSMAPGLERLNILPFRVAAYDKTQSQMAFFDPSRAQDFLFISGTKMRNFAKNNELPPEGFMCPGGWQVLVDYYQGLQKQESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INK6</accession>
    <name>A0A8T0INK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-carbonic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G218600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INK6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035809029" description="Alpha-carbonic anhydrase domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="3">
        <location>
            <begin position="44"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0584569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="282" mass="31804" checksum="C640BC28C6E0BAEA" modified="2022-10-12" version="1">MVSSATNAVAVVLLLQSCWWIGALAAPLHDITVEGGERHGGGEVHWDYSDGPHGPAHWHELKPEWAVCKTGKQQSPLDVDPNDVVSKSSLGPLWYEYRLERTPATIVNEGHAVVVEFPADKSYGYISIDYWSYQLRQFHYHMPSEHRFSNSSYPLEIHQVYRANHPAIRTGNTLAVVSFLFVEGDESPFLAQFCDKLPSYQTPNVKSNIGNITLLEMSKSYGRYMGSLTTPPCTEKVYWTMNWNTLTASKRQLEKLRAALPHANNRPTYPSTGRDLGVWRSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INW3</accession>
    <name>A0A8T0INW3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G228500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the plant self-incompatibility (S1) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060320">
        <property type="term" value="P:rejection of self pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010264">
        <property type="entry name" value="Self-incomp_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31232:SF18">
        <property type="entry name" value="S-PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05938">
        <property type="entry name" value="Self-incomp_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0964">Secreted</keyword>
    <keyword evidence="3 6" id="KW-0713">Self-incompatibility</keyword>
    <keyword evidence="5 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035964434" description="S-protein homolog" evidence="6">
        <location>
            <begin position="19"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0584695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="17722" checksum="4DD4472F917DF58A" modified="2022-10-12" version="1">MATAKLLILMVLIKVASASYDPSLPYYLLFQNRLPGQLNVHCVTKNNDLRLHPMPPGADYKFFFKLNFWLSTSFHCRFNYVGTNMWQAFETWRGPGFWFKDSWPCRQCTWMVNPDGFFRAQENETLVMIWPWRRDPEKYLVESKLPESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQF7</accession>
    <name>A0A8T0IQF7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G255000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035924721" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="54" mass="6219" checksum="01B8E29958496014" modified="2022-10-12" version="1">MIVVLSLLVSSPCACKVVAVDSYEFRYFRSSLRVWIEDYCRVRLIACRGRNTSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQJ3</accession>
    <name>A0A8T0IQJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G002800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040306">
        <property type="entry name" value="Os02g0753200-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35321">
        <property type="entry name" value="OS02G0753200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35321:SF1">
        <property type="entry name" value="OS02G0753200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="229" mass="25038" checksum="F88FBC1322A9CE2E" modified="2022-10-12" version="1">MSLSLVQGYDSPEEVPQDYFSNSDDEYASDGFKEKVAPVIKPSKLQQEKPPARTSELPTAFEMFTEVTGPPDFLKHSMTARVNGDLTSMTPTDFSRGYIAPKEPKPKHTPTTVAVVQAKPQVSNVEQDTANAAIAAKKGAPGVGLPPAEDAANLLRMCLNCGVPKTYSGAKESMVCPLCDDRPVVAGTEEKNKRGNKVKDKEHSKRMKGQSAHSTWKSETEMHLRQQFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IR73</accession>
    <name>A0A8T0IR73_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G075600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IR73"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="139" mass="16206" checksum="DA8C6272A6D4994E" modified="2022-10-12" version="1">MPLQRRRMTLPTIPEESEFIVDDSTIMMTMVKRKMDSNMLPAAAQLNGHLLKRCKHIRPDVADMLDQEYEEITLPPTKLHRLSHFKHAKDVTKTLVQKLFPNLRRSEHSDEQHDNTNCHHIRRSIGISLGVRSSLQYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISQ3</accession>
    <name>A0A8T0ISQ3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Cation-transporting P-type ATPase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G011200</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01657">
        <property type="entry name" value="P-ATPase-V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF11">
        <property type="entry name" value="CATION-TRANSPORTING P-TYPE ATPASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="379"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="547"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="581"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1043"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1069"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1108"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1159"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1188"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="1256"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="14">
        <location>
            <begin position="324"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="13">
        <location>
            <begin position="417"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0585433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1296" mass="146053" checksum="504919E4070F96D4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITC5</accession>
    <name>A0A8T0ITC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Histone-lysine N-methyltransferase ASHH2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_2G048800</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046975">
        <property type="term" value="F:histone H3K36 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
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    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
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        <location>
            <begin position="450"/>
            <end position="504"/>
        </location>
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        <location>
            <begin position="568"/>
            <end position="618"/>
        </location>
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        <location>
            <begin position="620"/>
            <end position="737"/>
        </location>
    </feature>
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        <location>
            <begin position="745"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="158"/>
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        </location>
    </feature>
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            <begin position="228"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="300"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="399"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1029"/>
            <end position="1197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1298"/>
            <end position="1475"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="61"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="164"/>
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        </location>
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        <location>
            <begin position="237"/>
            <end position="247"/>
        </location>
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            <begin position="300"/>
            <end position="309"/>
        </location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="339"/>
            <end position="353"/>
        </location>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="425"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1111"/>
            <end position="1128"/>
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    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1138"/>
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            <begin position="1299"/>
            <end position="1314"/>
        </location>
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            <begin position="1353"/>
            <end position="1364"/>
        </location>
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        <location>
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        <location>
            <begin position="1457"/>
            <end position="1472"/>
        </location>
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    <evidence type="ECO:0000256" key="1">
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        <source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51050"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51215"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0585908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1565" mass="169355" checksum="6321496A5B897729" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITQ9</accession>
    <name>A0A8T0ITQ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G086200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG0586379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8101" checksum="5EBE83B2565E647C" modified="2022-10-12" version="1" fragment="single">MPKISSATPPPLPLLHNRPTPSCRHIPRPIHPLPIPLNPWSRRRRIPAAAWLSAKLETQQLGFMASNLGEVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITV4</accession>
    <name>A0A8T0ITV4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G089400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11389" checksum="5531086C781E0412" modified="2022-10-12" version="1">MNESLLAARFAMSLLSTCDNKQRPSNVLHDLHTFEDPILALNYVSALPHLKNVIKDVDIIMNGRNEVGVRAPTQRLQHNNFYESVKEPGLVSFLNTQAANAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV61</accession>
    <name>A0A8T0IV61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD(+) diphosphatase</fullName>
            <ecNumber evidence="3">3.6.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G110700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the janus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.22" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006742">
        <property type="term" value="P:NADP+ catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03429">
        <property type="entry name" value="NUDIX_NADH_pyrophosphatase_Nudt13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.20.20">
        <property type="entry name" value="Janus/Ocnus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007702">
        <property type="entry name" value="Janus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038596">
        <property type="entry name" value="Janus_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050241">
        <property type="entry name" value="NAD-cap_RNA_hydrolase_NudC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015375">
        <property type="entry name" value="NADH_PPase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049734">
        <property type="entry name" value="NudC-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015376">
        <property type="entry name" value="Znr_NADH_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001299">
        <property type="entry name" value="PRK00241.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904:SF8">
        <property type="entry name" value="NAD(+) DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42904">
        <property type="entry name" value="NUDIX HYDROLASE, NUDC SUBFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09296">
        <property type="entry name" value="NUDIX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05005">
        <property type="entry name" value="Ocnus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09297">
        <property type="entry name" value="Zn_ribbon_NUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143724">
        <property type="entry name" value="PHP14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="10">
        <location>
            <begin position="243"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="465"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR607702-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR607702-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0586706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="58473" checksum="3E86AE647B245F0C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY70</accession>
    <name>A0A8T0IY70_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G194500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY70"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="169"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="435"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="466"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="564"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="636"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="727"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0587829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="755" mass="79159" checksum="62D40204CD3C5044" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYL3</accession>
    <name>A0A8T0IYL3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G271700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10892" checksum="0AEEB0F5C8A4588C" modified="2022-10-12" version="1">MSSPDDDDDGGGPLCRTNKGSQVHNFITSPALSSPGIPDDAVLNHSLREHQQQFELTRWYPTYLNTSCLAFKNIIPVAPIYSPASVADLDLEQLRHIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYV8</accession>
    <name>A0A8T0IYV8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G276300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="499" mass="55541" checksum="B30EB4B5F35AD121" modified="2022-10-12" version="1">MGLPLCAATRCPSQNDCQGYITTNAGNPELLAHLVACCKVLCSEGDKGILALQCGGASNSGAYFIASYIVVLTIAAFGMLIVGLSVKFKRLSFLISAFGTAIFGTAVTGIYVTYVTSSFTYLQALVPAVGAMIIAVFSYFFAGFEYNVGVTYGSGPLVALLTAVIPIWKAVPENRDSNRVALTMLFFAFLWVLHSVSFRVLGYRVLWRHFEAPKRREAGNPVNVCYLLGAGQSHPTWKTPVGQTTCLLFMAFAWAIARAARHDLKNQQCEADWVLNAMIWIPPSLMTAAFVYILLSALRGRTIKHKIRAILYTEERVGEYPGMQYYREFRKFLRASLSHYKQVVALHRRGRNTYTTEVVPEDMVETLDKVIGTLAWLLALFGLLMGWPVTKAMSCMAHFVTTTVSEEHQEGAKRVLTASYVGPYEQRTSRMAKMRSDLNTADDETGRYINLPYLLDTISHEELHALLNRPNEPRKLEPVKSKPKGLKTAKYSQYKTLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J516</accession>
    <name>A0A8T0J516_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-carotene isomerase D27-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G062700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J516"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038938">
        <property type="entry name" value="D27-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025114">
        <property type="entry name" value="D27-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591">
        <property type="entry name" value="BETA-CAROTENE ISOMERASE D27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33591:SF4">
        <property type="entry name" value="OS08G0114100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13225">
        <property type="entry name" value="D27-like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-carotene isomerase D27-like C-terminal" evidence="1">
        <location>
            <begin position="149"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="274" mass="30220" checksum="2738E20DB17FB1BC" modified="2022-10-12" version="1">MHSVAVRTPWEGACTSLRSSRNHESRVATNSRPCVVRCGVAEPDGKPVPFGQLTRYNDNLLDKAFMALFRRKMEQFTGKSTPLQGYEGFVDVSKKIMQGRTAVEQRAVVRNVLLSLLPPGAPAQFRKLFPPTKWSAEVNAAITVPFFQWLVGPAELMEIEVNGVKQMSGVKITKCRYLENSGCVGMCVNMCKIPTQDFFTNEFGLPLTMTPNFEDMSCEMFYGQAPPPIAEDPAIQQPCFASMCSIAPPKSTACPKLQQVAQDLSPSEVSLSEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6G5</accession>
    <name>A0A8T0J6G5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G158200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6G5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042856">
        <property type="entry name" value="RSP14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599:SF1">
        <property type="entry name" value="RADIAL SPOKE HEAD 14 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15599">
        <property type="entry name" value="RTDR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="483" mass="54406" checksum="0F37759E0F6CEFD2" modified="2022-10-12" version="1">MPRQPDKFDKRDRRVEDALIADDKRIREEKARLAALEKAKKKQKPPDDRNIVRSEQAKWCEDEKQVNWFHDNPNEDGLMRPYLQWRYCLKQLGVSGTDIIAVPWPNDVNNERAYPLLNCERHGHDIWMHQAQPNVTPQLPSTVTPGHLNFMYSKMARTLKSNLLIVRQKSVRWCVELLCVPDNRARCIAAGLLPILAGMIPETDLYIRQQLALCFKYFSAAITTWNDLVELGCIRGLIEMLRTDDVVLRCNALDALNDCALSCEVRDSIVEDGTTLPFVVQGLAKDTDPGNVCFAMDLCSKCMGSLNYCQKAIDQVLAAGGVPIVLKLAKTVYQPTMVSCGRFICLIGFEEKGRKQAVSLGAVAVFVPYIDHVEARIMAYGTAALLSLTLEIKGKKDFIIANGVPLMTAMIHLTDGELSFLAMNLIINVTEDPAARRKVQHGIGICRKLILETFNGTLKKCARQTIQELQFTSRAYQNLRDVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6S2</accession>
    <name>A0A8T0J6S2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G117800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6S2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="6">
        <location>
            <begin position="53"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="20965" checksum="2048AEF6B352CF03" modified="2022-10-12" version="1">MANQTQHGDHLDTESESESESLRLWFHSVDTDHSNSINVDELQVALEASNLRFPKTIVAQMIRMYDADHNGSMSFEEFTSLHNFLNTVHFAFSNVARNQQSISLNEVYMALHQAGFSLDQPSFLTTCQSFDPTRSGKFEVNDFISICIFLQSAKNLFTAFDTTKQGRISLDYNQFIYCAANLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J728</accession>
    <name>A0A8T0J728_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ATP synthase F0 subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G113400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J728"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035763408" description="ATP synthase F0 subunit 8" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="53" mass="6050" checksum="5BAA2449E7323A3C" modified="2022-10-12" version="1">MWVVLFSFFWLVEVVASVLSSKCFLTELTHLVFPNFIFVAGQGVKLHCFGEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J992</accession>
    <name>A0A8T0J992_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G204200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J992"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006461">
        <property type="entry name" value="PLAC_motif_containing"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01571">
        <property type="entry name" value="A_thal_Cys_rich"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15907">
        <property type="entry name" value="DUF614 FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04749">
        <property type="entry name" value="PLAC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="157" mass="17167" checksum="97AD76B0ABFE7FEA" modified="2022-10-12" version="1">MSNPESSPVVSLGGKTGVTISAPASRLATPPALLPSAPQPWSTSIFACYKDIGSCCWTMFCPAATFGTLANALDNKKGTKANCCTYFLRQFCCATASLSSKYRARIREKYNLMEKPLSDFATHCFLPQCALCQEYRELKRFKVELGSKAPPSQSMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAL2</accession>
    <name>A0A8T0JAL2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 20">Peroxidase</fullName>
            <ecNumber evidence="4 20">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_1G228900</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="17 20">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="17 20">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 20">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="20">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="4 20"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAL2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17 20" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 20" id="KW-0349">Heme</keyword>
    <keyword evidence="20" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="12 17 20" id="KW-0408">Iron</keyword>
    <keyword evidence="8 17 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 20" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0964">Secreted</keyword>
    <keyword evidence="9 20" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035967317" description="Peroxidase" evidence="20">
        <location>
            <begin position="32"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="21">
        <location>
            <begin position="32"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="18">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="42"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="75"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="124"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="203"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0592152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="320" mass="33640" checksum="9A6D6B2DC8D3DA33" modified="2022-10-12" version="1">MGESQGTLVGVAAIFLTVAVVTLYMSNAAEADLVVGHYANSCPTVETIIADSMKNSIASDSTVAPGVLRLAFHDCFVRGCEASVLLDKANSEKTAPINVNLHGFEAIDAAKAAVEKACPGVVSCADILQYAARDAVVLTGGQSWDVFAGRRDGTESNAAEPATELPLQTMTVSQLLSVFALKNLNAAHMVALSGSHSIGVAHCSFVTDRLYPNADSSIPADLLASMKASCPTAAATTQLNLDEQTPNTFDSKYFDNIINNRGLLASDQVLLDDSLTASEVQANNGANFGTKFAQAMVVMARYQVLIDNAGEIRTNCRNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAX8</accession>
    <name>A0A8T0JAX8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HEAT repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G289400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAX8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055037">
        <property type="term" value="C:recycling endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032367">
        <property type="term" value="P:intracellular cholesterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021133">
        <property type="entry name" value="HEAT_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040362">
        <property type="entry name" value="RELCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32059">
        <property type="entry name" value="RAB11-BINDING PROTEIN RELCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32059:SF0">
        <property type="entry name" value="RAB11-BINDING PROTEIN RELCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50077">
        <property type="entry name" value="HEAT_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="HEAT" evidence="1">
        <location>
            <begin position="912"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1104"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="219"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1109"/>
            <end position="1119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="126455" checksum="5EFAA795EF28D72E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC09</accession>
    <name>A0A8T0JC09_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Citrate transporter-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G322600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43302:SF5">
        <property type="entry name" value="TRANSPORTER ARSB-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="570"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="617"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="682"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="9">
        <location>
            <begin position="18"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="Citrate transporter-like" evidence="9">
        <location>
            <begin position="530"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="260"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="337"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0593347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="703" mass="75932" checksum="4273D2167251E238" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC98</accession>
    <name>A0A8T0JC98_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G337000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC98"/>
    <dbReference type="OrthoDB" id="2015991at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="773"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="8">
        <location>
            <begin position="57"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="8">
        <location>
            <begin position="406"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0593534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="832" mass="95472" checksum="C851983B9AC95E56" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JFN2</accession>
    <name>A0A8T0JFN2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G332500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JFN2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="17862" checksum="23AE92047FEC6AA9" modified="2022-10-12" version="1">MRSQTTTAPRPKLDRPGPPVLPPQICSKTRGVAANTSNLARPGVSSSSSSSSSATTALSPANSTPPATRQPGRSLWESPQPSQAKPSPRAAFARGSLLAVPIVAPAASRRSTEHSHGPRKRRPRCRVGAQRQLPSGAAPRLPSRQAPPESRDPSSLACFREETRLRPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7Q0</accession>
    <name>A0A8T0G7Q0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G047800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7Q0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="120"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="4"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17881" checksum="326DC6C483E490CF" modified="2022-10-12" version="1">MEELKRLQSVMEDLQLKSDRLKEKLEKIAKLLPIPLTLHTSHHIQGDPTGRSSFQIKVNHCALCESSFTQMDILVAPCHCTYHLWCVVMQSMLADECANSECKETFTESWKKSLGLDKLPDYDLDKPPRQVNQPSQKRKHTNSDIGGVNFSKKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7Y3</accession>
    <name>A0A8T0G7Y3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">COX assembly mitochondrial protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G054000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7Y3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013892">
        <property type="entry name" value="Cyt_c_biogenesis_Cmc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22977:SF5">
        <property type="entry name" value="COX ASSEMBLY MITOCHONDRIAL PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08583">
        <property type="entry name" value="Cmc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0553988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12504" checksum="DA99708AF241A2B5" modified="2022-10-12" version="1">MHWCAIARPPIRHCILRPRGGERHGDPGGCRRVSHEEEGRRSKMKAQALKECDPIVAKFAECAKGRTFSVIWACRAQSKETNACLHQYTNDEAFAKYKKLYEEETSQKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAC1</accession>
    <name>A0A8T0GAC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G041400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0556296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="18198" checksum="67450F07E21329D0" modified="2022-10-12" version="1">MTTCRRKLEVQGVKKCRRDHPLRCFTLGGHAERLQRYQQRIGARTVRQSKGTTAQVQRDGAFHTLLGTCAHLGLSTCKLPALGLFARNPYPAGPYRASGVSCPRCSCSLPIGFVARPSALLRFPPQPHHSFSIARDFWISGVHENGLFPFLQVHFTYHLLLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBX5</accession>
    <name>A0A8T0GBX5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G060300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035776475" description="Secreted protein" evidence="2">
        <location>
            <begin position="25"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="100" mass="10701" checksum="A4D0FABE6B7D4A15" modified="2022-10-12" version="1">MAFLNAKFAVFIVVLVALVQLHECGRAPCVSTGDATAVDFDGGDVPQSMECTEKVTVDVGAGELGAKPARLLRGERMLRRWAQSPPPMNPYRPGSNSDDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGF1</accession>
    <name>A0A8T0GGF1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Xyloglucan endotransglucosylase/hydrolase</fullName>
            <ecNumber evidence="6">2.4.1.207</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G024600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Secreted</location>
            <location evidence="6">Cell wall</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Secreted</location>
            <location evidence="6">Extracellular space</location>
            <location evidence="6">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Contains at least one intrachain disulfide bond essential for its enzymatic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.207" evidence="6"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGF1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016762">
        <property type="term" value="F:xyloglucan:xyloglucosyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042546">
        <property type="term" value="P:cell wall biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010411">
        <property type="term" value="P:xyloglucan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010713">
        <property type="entry name" value="XET_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016455">
        <property type="entry name" value="XTH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06955">
        <property type="entry name" value="XET_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005604">
        <property type="entry name" value="XET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0052">Apoplast</keyword>
    <keyword evidence="6" id="KW-0134">Cell wall</keyword>
    <keyword evidence="6" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="1 6" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035969013" description="Xyloglucan endotransglucosylase/hydrolase" evidence="6">
        <location>
            <begin position="28"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="7">
        <location>
            <begin position="4"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005604-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="295" mass="32895" checksum="98B5015A58C65A34" modified="2022-10-12" version="1">MGSSSGSSQCVALMALLCLSFVVGGQALLSDEFNTWQPQYVNYWTNGKGLTLTLDQGNSAAGCGSKDSYLYGSFGAWIKLPGGNAAGTVATLYLSSPFPDQCEFDLEFLGHLEGRPRKIHTNVFVDGKGGMEQQIYMPGDFDPTAAYHYYSFEWHSDMVVFYVDWKPIRMFKNLQGTVPGFNYCNHKAMSLYLSIWDGSNWATEGGSIKLDWNAAPFQCHYTDFVMNGCKVNSWDTNAISACQQSSYATGPGVTPEQWQYMESIKNNATLVKYNYCTDYARYPQGTRPECQYNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI40</accession>
    <name>A0A8T0GI40_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G045300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035920072" evidence="1">
        <location>
            <begin position="23"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5864" checksum="69114825C89CBF96" modified="2022-10-12" version="1">MSLREFSVHLIAVLILLYRHQSNHPCIALHCTNHLITDTHSPSFVCLLALIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI46</accession>
    <name>A0A8T0GI46_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SMP-30/Gluconolactonase/LRE-like region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G159200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SMP-30/CGR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004341">
        <property type="term" value="F:gluconolactonase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019853">
        <property type="term" value="P:L-ascorbic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907:SF65">
        <property type="entry name" value="ALDONOLACTONASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10907">
        <property type="entry name" value="REGUCALCIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63829">
        <property type="entry name" value="Calcium-dependent phosphotriesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SMP-30/Gluconolactonase/LRE-like region" evidence="4">
        <location>
            <begin position="26"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="211"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR605511-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="312" mass="34789" checksum="13DC2B2548182A48" modified="2022-10-12" version="1">MAEVAQSKCGTDPKITIFYEAGAVVGKGAIWDPETENYHYTDITGMTMHRLHVPTQVRKDYNLGTQVGAMALIEGGEGLVLAFEDGFAKWSFVHENLTVLATPYGKYSGWRMNDGACDSRGRFWAGRLFKTDESKPGEIYKLETDGKTATKVIDNICCTNGLLWSPDNTKLYCGDSTLKKIFVWDYDEESGTPSNRRLFLDTAPLFDGVPDGATIDTEGYLWVCFFDGQKLVRISPNAERVCTIDMPVKRPTQPSWYGEHLDELLVTSASLGVDVTQWPLSGHVFHLKPAGAQGRLKAKYHYNPICRYVTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIQ6</accession>
    <name>A0A8T0GIQ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G027400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIQ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17615">
        <property type="entry name" value="C166"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035818601" evidence="1">
        <location>
            <begin position="24"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="537" mass="58120" checksum="B4E212A7986AEB6B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIV8</accession>
    <name>A0A8T0GIV8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G100800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005202">
        <property type="entry name" value="TF_GRAS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31636">
        <property type="entry name" value="OSJNBA0084A10.13 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03514">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50985">
        <property type="entry name" value="GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="117"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="79"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="150"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0559391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="773" mass="85073" checksum="AED2F95B47292FBC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPF8</accession>
    <name>A0A8T0GPF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Omega-hydroxypalmitate O-feruloyl transferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G158200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF231">
        <property type="entry name" value="BAHD FAMILY ACYLTRANSFERASE, CLADE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="458" mass="50739" checksum="28FD350A0B8C4F8E" modified="2022-10-12" version="1">MTYCNPDEVEAGTAVPENGPSFNNFTVVVHAMKVVQPAEVTKEETIYLTNIDQMLVVPVESFFVYLPNSKKSSESVFWVLEDALAKVLVPYHFMAGRFEVNTEEGRLQVKCNRAGVGFVVASSEQTIEDLGDLKLMNPGFRKLVPSPPGDNVSLFDDFLLMVQVTRFRCGGFTVGFRMSHSLCDGTSSAQFFRSFCKLARGAPLTEFPDLDRTILKPRDPPAPEFNHPECFRSGGVIPNGAGTVDNIDIVAPQYITKHIPMSLMEIQTLKTIAMADGSIKRCSSFEVTIAHFWQARTRSLEFAPDELTNLLIAVDFRAKMHPPIQPTFCGNTIISAHVSALASEVAHNPLSYCVAKIQEAVARIDERYVRSALDWLQLHGGVPAIGSAKDMLVSAWWKFPFYEHDFGWGKPVHSGPPSGSTPQFALIVSNGTEDGGLLLLVSFQPHEMVKFERYLKDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPX9</accession>
    <name>A0A8T0GPX9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G075000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPX9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="14378" checksum="22B5CD17BA7125F5" modified="2022-10-12" version="1">MWFAINSHLEGHNYHCQTANPAPSPLFPPHCNVLHLIPSPPTMEERCRLTELSTARSCHNPSLTGHNTTSVSTSGDDHNLFDMNTFTSKCNLSATVCMLLVSMMMFPGQVLAFYTVTSCEMEPGVQHGGVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR52</accession>
    <name>A0A8T0GR52_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G159100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR52"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="522" mass="57371" checksum="BDFBC4BC9C6AA949" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRT5</accession>
    <name>A0A8T0GRT5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA-binding S4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_9G053800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000003">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.580:FF:000013">
        <property type="entry name" value="Ribosomal large subunit pseudouridine synthase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="entry name" value="Pseudouridine synthase I, catalytic domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050343">
        <property type="entry name" value="RsuA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00093">
        <property type="entry name" value="pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683">
        <property type="entry name" value="PSEUDOURIDINE SYNTHASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47683:SF2">
        <property type="entry name" value="RNA-BINDING S4 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="4">
        <location>
            <begin position="131"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0561307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="381" mass="41573" checksum="08C84B0D183130CE" modified="2022-10-12" version="1">MGGLATPLRCAHASSLLFATKPSLIQPRLASRFARLSLAINCVAQPESGASEGKRIVPSRVARPVLDINDKGEIYMKDVGGVASVEEGEVKRRAKPDSTRISVGVKKSSAVPRYSKAARRFYNETYRAESERLSKVLAAAGVASRRSSEEIIFAGRVKVNGKVCTVPQTPVNPLKDIIFLDGRSLPKKAPPKFYFALHKPKGYICSSAKDAPKPVLSLLEEYWKIWDKKNPGGVRPRLFTVGRLDVATSGLLLITNDGDFAQRVSHPSSGLTKEYIATVAERVTKRQLQLIAAGTKVQDVHVVPTEVEPLPVEAGDARQRIRIVVCEGRNREVRELVANAGLEVLGLKRVRIGGLTLSRKLGPGKYEALTEIQVNTVLNLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRT8</accession>
    <name>A0A8T0GRT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G141100</name>
        <name evidence="2" type="ORF">KC19_9G141700</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRT8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10726" checksum="C158289DCF2847A9" modified="2022-10-12" version="1">MSFSLNPISPCCENTSILKKEDTHLWTSPRAVIKLVAHSKKILSIRVYMVVIQISGMIERCTRGITIGNYLNIRILELDCIVKLHVIAWLTMRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS88</accession>
    <name>A0A8T0GS88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G189100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46629">
        <property type="entry name" value="OS01G0917900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="653"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="51"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="89"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="567"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="594"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="701" mass="74948" checksum="FCFE6F5BA8DA1094" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSK7</accession>
    <name>A0A8T0GSK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G057600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSK7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054416">
        <property type="entry name" value="GST_UstS-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22041">
        <property type="entry name" value="GST_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="279" mass="31481" checksum="A5C5D3788BB4C7E7" modified="2022-10-12" version="1">MTDAEPLVFYDIASTVEPRSYAPNPSKTRLALSFKHVPFKTTWVDIPDIADVRKRLNCRATRKFDNGLDYPTLPMLQDPASGRVVGDSFDIANYLEDTFPDSGGCLFPPNSTRTGLNYESPNKDTAFFAPLTSNQGSKNEDYAKFNMHVDATFSAYVVLVGQYLPFNPNSASTVRALFVERAHLSSWNDICIQGEPREQLKAAFRVALTSLAQLYMIHETGPYLEGQTANYADLIVGGWLNMFSITMPEEEWKEFRTWHDGVFAQLHDALQENYFECLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSW4</accession>
    <name>A0A8T0GSW4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G082500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF7">
        <property type="entry name" value="OS05G0564100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25500" checksum="66F129C6132F2C1A" modified="2022-10-12" version="1">MKFSAYPVVDLTVGGETLHFEQDNGSMYVGTSVWPSSLVLVKWVEHVFEKGLSSVCEGLSPATFAGKKGVDLGTGVGVAGMGLALMGLNCLLTDISPVMPALKRNFKKNLGSTSLGSAGKAGVKTGKVKVAQLYWGNVKQIEALKPPFDYVIAGDVVYLENIVQPLLETMSALAGPETVIILGYQIRQAEAHEMFWRLCPEYFTVVKVPREELHPEYCWPENEVYVLKKKCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTT9</accession>
    <name>A0A8T0GTT9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G074700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="13293" checksum="9DEE48414E3DC096" modified="2022-10-12" version="1">MQPLPYSASPLTPPLHNPTYHRRFTAQHTQHTTAASQPNTPNIPPPLHSPTHHHHFTAQHTITASQPNAPPPLHSPTHHHHFTAQRTTTASQPNTLSLAHTLLGPLALNHRIPSHQAPLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUN1</accession>
    <name>A0A8T0GUN1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G026900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUN1"/>
    <dbReference type="OrthoDB" id="1924952at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019005">
        <property type="term" value="C:SCF ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031146">
        <property type="term" value="P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09917">
        <property type="entry name" value="F-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874:SF9">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12874">
        <property type="entry name" value="F-BOX ONLY PROTEIN 48-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="137"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="479" mass="53370" checksum="4302A27CE19665A3" modified="2022-10-12" version="1">MDELVGHTGEIDEGEEDALDAALDMELAATYVKHPVVNPSQSEPGKHHVREEVVDVIQEPAMSQLTFAFPGWEIGISKGEKLRMPSVSRIINDPQSAPSKKGKQVKSPTGSAGSIRAESVASDDPSVPVDGCPADSVDDDLLACVFMRLNVKDLCASMRTCRRWHRVACKEDVWTHIPLPANVPGALPRWMEVRNAGISMDLRIRFQVFRRGYEFVRSALNAWWDHGQPDGKHPSVIFRSLTQKLVINDWSLLYEAFGTAFSDRADRIAAIILAVIQRIEVSKQFMRREMATELGSGNGLAEMFSNLPSKPDGDSNASGNDREGNMWDEVEVQEVWVLVLSLWRRYKRWLMLVVSHCPELNHEVMAERARSNALATTPTVYGKGIICFRSQVILKYGVRSLLQATWSGLASAKRSGIASDNQLDLFRSADHLFQETSVLDDLTLSPTTFTQQKLRRCFGNETSSKTKPTRGKSNSTALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW76</accession>
    <name>A0A8T0GW76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G141900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="62"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35286" checksum="90276909F2E54782" modified="2022-10-12" version="1">MSGREVDAEGGGMRRGEDCVEVGVQASGVDRVAPCDGAGVRSPYPAVVDPFKRRVALREYVKQLRGDNKENERGKDSEVSEKSPVSGGVVKKTLGLCRRHVGGVAAVAVSREGMLRDKRKFNAPRQTPEKRQRPDQVDVSPGTELSRMESRMVVEEGGEEMSGGMRQPVFSFASREHVQLELSPGQVSGGDGGDGVAGARWSPYGGRDSFLSPAPSPAPSPSRQAQLPESYTLPFKWQAPEPKTPTIRKPLAPVNIPVNRQTVDLHPSPMDQPRPNFSGSLERNSSGSGGSLFQTASGKPFQASAAAKARAALLFESDAELADFFAMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWP3</accession>
    <name>A0A8T0GWP3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G032400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWP3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396">
        <property type="entry name" value="METHYL-CPG BINDING PROTEIN, MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396:SF46">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MBD" evidence="7">
        <location>
            <begin position="696"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="115"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="183"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="364"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="759"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1086"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1149"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="115"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="238"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="400"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="759"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="795"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="818"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="860"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1184" mass="129501" checksum="ED729972D49EBD89" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ33</accession>
    <name>A0A8T0GZ33_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G149200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ33"/>
    <dbReference type="OrthoDB" id="1938612at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.890.10">
        <property type="entry name" value="cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007858">
        <property type="entry name" value="Dpy-30_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05186">
        <property type="entry name" value="Dpy-30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11722" checksum="D187A4E5B0F8084A" modified="2022-10-12" version="1">MSEKKGSVAGEKKKSSVRGSQIAVAVVETVPLTPEVWFDLKEEEAALAQAAKEAQELLEMRALPVRQYLEASVVPLLLHGLQLLAIERPENPVDFLAKYLLEKNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0F4</accession>
    <name>A0A8T0H0F4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G124600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0F4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035721764" evidence="1">
        <location>
            <begin position="19"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5473" checksum="CFBD8436C8F0811F" modified="2022-10-12" version="1">MELVALALFMLNLTRVDGSAEGMFQPPEDALRFRLLSIQISMMTVNSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Z3</accession>
    <name>A0A8T0H0Z3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G054900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0Z3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="7337" checksum="3D5DA41A48646C6D" modified="2022-10-12" version="1">MLVDEVVEQKLPSFYFFCFVFVKGFLWLSFKLGVKEVHERLRDSVANCRHILHYVVVYQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2D3</accession>
    <name>A0A8T0H2D3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G041900</name>
        <name evidence="3" type="ORF">KC19_7G050500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2D3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="246"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="300" mass="35791" checksum="54E926517E22689A" modified="2022-10-12" version="1">MGNCNHKFHITCIAKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHEFDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTANDAGMDDFSWMTHDHEVEMRASEIPDAKDREFFCRNFGGHWSIHRNRFFRFPKPEVVVDADGKRREVERDYGQLDEYKMYDRTPVGRALVLAKLEEAIQHRRTFTEESFKYSDLDYWVITKKFDDALHKIVNDWRRALRAEDNSSRWSRNRIEKIVQETKRNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3D7</accession>
    <name>A0A8T0H3D7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trafficking protein particle complex subunit 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G062300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3D7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021773">
        <property type="entry name" value="TPC11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374">
        <property type="entry name" value="FOIE GRAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14374:SF0">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11817">
        <property type="entry name" value="Foie-gras_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trafficking protein particle complex subunit 11" evidence="1">
        <location>
            <begin position="37"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="577" mass="64076" checksum="29E2D46E16DBE110" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5X7</accession>
    <name>A0A8T0H5X7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription factor CBF/NF-Y/archaeal histone domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G083500</name>
        <name evidence="8" type="ORF">KC19_7G083700</name>
    </gene>
    <organism evidence="7 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NFYB/HAP3 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5X7"/>
    <dbReference type="OrthoDB" id="386949at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001228">
        <property type="term" value="F:DNA-binding transcription activator activity, RNA polymerase II-specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000978">
        <property type="term" value="F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22907">
        <property type="entry name" value="HFD_NFYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000035">
        <property type="entry name" value="Nuclear transcription factor Y subunit B-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027113">
        <property type="entry name" value="Transc_fact_NFYB/HAP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003956">
        <property type="entry name" value="Transcrpt_fac_NFYB/HAP3_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064">
        <property type="entry name" value="CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11064:SF189">
        <property type="entry name" value="NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT B-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00615">
        <property type="entry name" value="CCAATSUBUNTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00685">
        <property type="entry name" value="NFYB_HAP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Transcription factor CBF/NF-Y/archaeal histone" evidence="6">
        <location>
            <begin position="39"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0566733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="23744" checksum="778A3CBDEF196919" modified="2022-10-12" version="1">MADSYGHNAGSPESSPHSDNESGGHYRDHDASVREQDRFLPIANVSRIMKKALPSNAKISKDAKETVQECVSEFISFITGEASDKCQREKRKTINGDDLLWAMSTLGFEDYVEPLKVYLHKYRELEGEKASMAKGGDQSGGKESSQGGMGSMGMGGGMNGMNGAMGGNMHQHGIPVSMQMMQQPYGQQAPPGMMYSPHQMMPQYQMPMQSGGNQPRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6K1</accession>
    <name>A0A8T0H6K1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Limiting CO2-inducible protein B/C beta carbonyic anhydrase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G145400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6K1"/>
    <dbReference type="OrthoDB" id="2014244at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040703">
        <property type="entry name" value="LCIB/C_CA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016:SF1">
        <property type="entry name" value="LIMITING CO2-INDUCIBLE PROTEIN B_C BETA CARBONYIC ANHYDRASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38016">
        <property type="entry name" value="UNNAMED PRODUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18599">
        <property type="entry name" value="LCIB_C_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Limiting CO2-inducible protein B/C beta carbonyic anhydrase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="28937" checksum="6CEFC2010DD234B9" modified="2022-10-12" version="1">MAEHLEGRQASPQALETIAKYFPVALVEDAFFQTAHDTLQELGFKRDNTFVLVNTCRDELARPISHFFDKHYGHTFNLSGISGIITAGTLGFIAATSHAPTNPDGRDKYVFIGATHTAVDENGKEGAVVREGQGSVSNACGAIEAILGEIHAGTQQNGTIREDNVEYDTLKKKIFAKNLPAHPTNFDLTKITAQAITHTIEDHIAKTVDPTKSDYAVIVGVQIHAGVKAGLWTPESVIDYFAPVTSYTVIKGVKHELKVEGKKLVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7C5</accession>
    <name>A0A8T0H7C5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G113800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7C5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="11812" checksum="1B0B8BE0BD769092" modified="2022-10-12" version="1">MVIMTSDRPKQHPSSGSITPRAGYLESPYVLFSRLHNGLTANTAKLLTTHPSRKLPTLLPLQHTSLSLLPSFCKTPLIHTKEATTLHGTSLRDEKARWGALEILGSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7Z3</accession>
    <name>A0A8T0H7Z3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G130100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7Z3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040275">
        <property type="entry name" value="At5g39450-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31370">
        <property type="entry name" value="F-BOX PROTEIN FAMILY-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="45"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="312"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="562" mass="61958" checksum="2716BEF4A572A20D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8I9</accession>
    <name>A0A8T0H8I9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G006700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8I9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="243" mass="27881" checksum="CCC3C19660C46BB5" modified="2022-10-12" version="1">MSQKKKDEAVWEDCGCPLSMAIGDFTPDVGAITSLPHMCTISSAEYTRHYIFDHVSYEKLINTAPDSPLAQWTQKRCQEERMFVARPPDRPIRPPEPWRYDEPPFDWALPSGWRAWAPSNPKLVFSDENSVEDYQMNLDSFFLYMNIKDPVKQEQMRDGVEAWVMACGEADVLIKGKHPSISDRCFVTSSGELFAYLFAAGDKLNDFLKDLKLRKRTRHLRRLVDLMIDAKVKIGGCGHTFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAT8</accession>
    <name>A0A8T0HAT8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ZF-HD dimerization-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G139600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAT8"/>
    <dbReference type="OrthoDB" id="1884189at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006456">
        <property type="entry name" value="ZF_HD_homeobox_Cys/His_dimer"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51523">
        <property type="entry name" value="ZF_HD_DIMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZF-HD dimerization-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="258" mass="28774" checksum="E7E755223CDF56F0" modified="2022-10-12" version="1">MGTAHHLDQAMLHSRNRGKCTKMHAHLGPGVDGCQLFDGENPNDMLCGACGCHMSFHVKLNVGSRYGLEKYEVIDLEPGLKRCKMSFEASPAESVGDNLDSPGLEVNSGTSHEDLARVFRANKIEEPVTVMPISIKPELRANNIKPNDSMMFADSPLYTRLCTKLKLIQQDYPEEIHGKFSIVHDEEHGFRVYCGGCDKRYGITKPGYSLGNFERGHLASKRHKDVGALDGRMKVQKMKDFLQQAELAKRTAKTMYCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAU4</accession>
    <name>A0A8T0HAU4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">At3g05675-like ankyrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G017000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038920">
        <property type="entry name" value="At3g05675-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058039">
        <property type="entry name" value="At3g05675-like_ankyrin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31060:SF4">
        <property type="entry name" value="1,8-CINEOLE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31060">
        <property type="entry name" value="OSJNBA0011J08.25 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25553">
        <property type="entry name" value="BTB-POZ_ANK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="At3g05675-like ankyrin-like" evidence="5">
        <location>
            <begin position="250"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF25553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="410" mass="45238" checksum="CE874F9E911B1796" modified="2022-10-12" version="1">MEGGAMQAVGSSWLVPSGVEAIDVSRPGVLVHQFHVMAAMMLWMVATCAKVILALLPSLVPLPVLTTFLRRISAVWDEYSSVSRVMRRRNGDDGDLRSRGVVSEGTIERALTQVLRLVNDVPASSNKYLFLLDMADRLIKENRMESGKYTSINRAALRRGFSRTINLLGQSLESRGQNQSFLGRLVNQILPSGGALVPSMAIPEPFGKIWSFVGNVLSPLTGWSLSKRPIHTEAARLANLADSDIAEKFAKELLWMTQKLIACGGMEDVVQQWSSASPLAELSLCASPKVQKSLVRLSALLCKGVVENTGTPHEVCVNLILAWLPLLCIATHGGDGPIFNSLEKGDLERELERLVVSLPETDQEQVLSTWLEHYAMSQSEWPNLQNCYNAWCYTTRKLELDMSKVMKLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAX6</accession>
    <name>A0A8T0HAX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G126800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0567329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9665" checksum="63DA8EC89B3412AE" modified="2022-10-12" version="1">MPLQQQFTLFPVPLVCSPHSAIRFSKLPHLLFDVLGGNPQRANRFEAQTSAKLRGLRSNEWDWHSREALVQQFFADSDRIRAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBJ3</accession>
    <name>A0A8T0HBJ3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G182300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBJ3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11501" checksum="76A017D4BFEB011D" modified="2022-10-12" version="1">MLSEPSMPAKQISLQCSLPPSLSPCSEEEPGNDVLMAFLYLLQSGFFTSHFHMPNPLFIPHHKCGAPMPKPYTTYCSALHYTKPSVIVKYYHRLLAAWALFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC95</accession>
    <name>A0A8T0HC95_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G088100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AP2/ERF transcription factor family. ERF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31241">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31241:SF62">
        <property type="entry name" value="DEHYDRATION-RESPONSIVE ELEMENT-BINDING PROTEIN 2D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13912">
        <property type="entry name" value="zf-C2H2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0010">Activator</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2H2-type" evidence="11">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="AP2/ERF" evidence="12">
        <location>
            <begin position="88"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="46"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="183"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="194"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0569401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="281" mass="31399" checksum="073E133DC363E99E" modified="2022-10-12" version="1">MARISRTTSYSSDSGGSQAGSPGPSTRPGSKTYMCKVCGNEFSSGQSLGGHMNVHRRDQRSPSSSHSGADYHSPGTDHQSGQNDWSQSYKGVRYRKEQNKWVAEIRPPKANRTWWLGTYSTAREAAYAYDVAITYFGSETSLNFDGHPIYEQIPKIDTDLPNQDFAAQLRKVVKKYGKMAMESGAGPSTGYQEETGRSSDRDQAGHQPQVLSWEDFPTTLPPPDSTTSDYNPFNVDDMMPQADPSEYNYQGQVNDSEASLYYGYGYQQQYGWPPYNPRDYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCY8</accession>
    <name>A0A8T0HCY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G010500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCY8"/>
    <dbReference type="OrthoDB" id="996720at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002673">
        <property type="entry name" value="Ribosomal_eL29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12884:SF0">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01779">
        <property type="entry name" value="Ribosomal_L29e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="42"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="65"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12653" checksum="0FE0A3C3A535AEDA" modified="2022-10-12" version="1">MGPLFIHPGKPLGKEEGFLGLEERPASSLSLPRLLVCLPERHSAAPPSGKMAKSKNHTAHNQSYKNHKNGIKKVKKHKYTSRKGMDPKFLRNQRYAKKHNRSGAAGEVEETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEA3</accession>
    <name>A0A8T0HEA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G057000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="24997" checksum="9D227B8CD1892593" modified="2022-10-12" version="1">MEELPPRSNMDDLSAQNSVENFLADNGVADLTISPVYQAGVDLVHPSRGMMRFVYEELSTRDNMELSTRDNMELSTRDNMELSIRDNMDKNSMWTDEEIEVANILLECESLILAREEEKEQRHTLYDAIKTTPRPKKKPCRYKDVEVNPNLPSTSKSFTCERCKSIFPNGQALGGHRKACNRDKNDLLLNSNEVTPSNHSQDDTVLDSKSKIKDISQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFT3</accession>
    <name>A0A8T0HFT3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G176200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47712:SF3">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47712">
        <property type="entry name" value="OS09G0555300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="91"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0570626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="464" mass="51315" checksum="6E867D31CD17D905" modified="2022-10-12" version="1">MDSFGEDLNSPLPKRMLASPPEMMEGVVMERPALARSGAHSSTVKAPSEIEPRAVTLRPLSERLGRITLRRAPVTAVEEQKRSADDLWSQLSDDMVEFILARLPLFPLKASRKVCKRWEAIISTPQFENLHKELGEQQPWLVCYCVNNLVPSKSHGVVYDVESDTWITLPPLQFPSHNYGSLAGASGLVYAIAGPGEDRFRYMLTSSSTSPENFGETWYETPAMAFPRSAPVVSVALGTGRTGFGHKVVVAGGVPDFEAEHSAVEVFDSETGAWEVYDDLPDDFSESSSRAWMSGVVCDNKFYVSLIHSWSIHVLDLCTKEWAAIEWEHPQNLICHHIMAIGSTLVVAGLCGDADQPEEIVLKIWKVSLKSNRLIQIGLMPRQVMATLGRQSALPRYNFLMTENLLYVSNSDAQDSALVVGEVSLQECKTQWRCLPSLSTSGHRFDHMITFCSSISISAHTSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG20</accession>
    <name>A0A8T0HG20_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G059600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG20"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="78" mass="8811" checksum="D81D3F276700476C" modified="2022-10-12" version="1">MTSSLLYLRSPQLLMQKSKRLLSLGHHSLTPETSRESALLTTEKAAIIPQQSHAWKVPAHHHHRRASSTRICDSESET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGC4</accession>
    <name>A0A8T0HGC4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G156500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14058" checksum="BA68288297FE963E" modified="2022-10-12" version="1">MRIDRPGGFGKTWCKYCSVLMNPGLSFLPLVRGGRSGGTMAQNALCGSLSMAQLNLLLRQISKSSQWVIFRRLMLVIFLISWFSMVMTSVYVRMSTDGEFPASFTSESTAPEPLFHARKLAAWSPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGP6</accession>
    <name>A0A8T0HGP6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G002900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGP6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="6662" checksum="21AA60B28363BC7E" modified="2022-10-12" version="1">MPWQGSYPTPAMQCSSRSKAMQKRLHECSRGRNLALALALALPLALPLALPLALPSRHALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ68</accession>
    <name>A0A8T0HJ68_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G190700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035726113" evidence="1">
        <location>
            <begin position="27"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10932" checksum="98F58085BE13BB08" modified="2022-10-12" version="1">MASCHHSARIAFLFFLLLAIPEMQECSRPFAPDQADTVLVHNDNWISNLVEAVDDGTAEHGSGATPIHNPMVRDIRGSRLLLFVKSPPLPPPSNPCCTGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLC8</accession>
    <name>A0A8T0HLC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG017400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000003">
        <property type="entry name" value="40S ribosomal protein S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_uS15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_uS15_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="uS15_NS1_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="RIBOSOMAL PROTEIN S15P/S13E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885:SF6">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN US15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="S15/NS1 RNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12273" checksum="666F9841C907B5CD" modified="2022-10-12" version="1">MVCVRRDTGGERGSDGLFGGFGPGIAEGLYHLIKKAVAVRKHLERNMEDKDFNFRLILIESHVHRLARYYKGTKKLLLTYILSEVERIILMTEDLELFRHQISNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMU5</accession>
    <name>A0A8T0HMU5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG056400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMU5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6734" checksum="5DCDFADD06E8E3AC" modified="2022-10-12" version="1">MLYRMAVEEVLVDDYTLPLSSAEVMRKGSDITLAGWVPMPRWQFQAFILSRVSACLLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN77</accession>
    <name>A0A8T0HN77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG081500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF173">
        <property type="entry name" value="MYB-LIKE PROTEIN K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SANT" evidence="5">
        <location>
            <begin position="70"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="6">
        <location>
            <begin position="75"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0572286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="202" mass="23137" checksum="E48C223D0E8D94D1" modified="2022-10-12" version="1">MEQCGMMIEPASSRKVKSMIPDHYLQNMDTLGLQQLEHLEKELEQAKKKILVLKAQEHRETSSPDTKQVSESRYWTNEERQRFKKALKTFGTDFAAIAKFVGTRSSTQVRTHAQKYYAKLLVADTRGQRLSLHCLKIGGKLPLHRERLNMPAAKWPRHLSQGSHTHACFIVGTLVHFPANLFIANKRLQALRQSWGSNNESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNE0</accession>
    <name>A0A8T0HNE0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG088700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNE0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="196"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27121" checksum="395A2A21A0DE68A6" modified="2022-10-12" version="1">MDQEKGAILAWMSIIFFNRDAKNHREPKLWLLDVPALSRIFQDSSHFLWSDDCYEDFTHLGNAAGYTFETFLAQLNVPFEPSGSCFACPINVDATFGNTSAGAARTEQGNPEPITPPQCQPFQGEDVDMEEVPGTDVNPDATEVVAEGNVRSPPLTHTDGDSEGVGAGLASSKAGEDRQMSSEPYVLENPFARGYGPVIQASGPSFGSPPPSEDLPNQSHRRRGVWRQWGGGGGSENSSSEDFHSHCAHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNY0</accession>
    <name>A0A8T0HNY0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">ADP/ATP translocase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">ADP,ATP carrier protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_VG100300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell. Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane.</text>
    </comment>
    <comment type="function">
        <text evidence="16">Catalyzes the exchange of ADP and ATP across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ADP(in) + ATP(out) = ADP(out) + ATP(in)</text>
            <dbReference type="Rhea" id="RHEA:34999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:35000"/>
        </physiologicalReaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 16">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNY0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005471">
        <property type="term" value="F:ATP:ADP antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140021">
        <property type="term" value="P:mitochondrial ADP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990544">
        <property type="term" value="P:mitochondrial ATP transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.40.10:FF:000001">
        <property type="entry name" value="ADP,ATP carrier protein, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002113">
        <property type="entry name" value="ADT_euk_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45635:SF50">
        <property type="entry name" value="ADP_ATP TRANSLOCASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00927">
        <property type="entry name" value="ADPTRNSLCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0050">Antiport</keyword>
    <keyword evidence="11 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 14 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="203"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="100"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="205"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="14">
        <location>
            <begin position="306"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00024143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00045250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU368008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0572499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="43815" checksum="38679FAC3A89AA98" modified="2022-10-12" version="1">MMGTERSNSRARGALHSLFGSSSNLITLLVPSSAHQRQLSPSYPVRALTTPMELSTYVHARTVARSGVLHFPTQVIYNAKVSFGNKVRPLSVVAHAVQEKSFIMDFMLGGLSAAVSKTAAAPIERIKLLIQNQDEMIKQGRLSEPYKGVADCFKRTMADDGVIALWRGNLANVIRYFPTQALNFAFKDHFNKMFGMKKDVDGYWWWFAGNLASGGAAGASSLFFVYSLDYARTRLANDSKSTKKGGGERQFNGLFDVYKKTMATDGIGGLYRGFVISCVGIVVYRGLYFGMYDSLKPVLLVGDLEGNFLASFMLGWSITIGAGLASYPLDTVRRRMMMTSGAAVKYKSSMDAFSQIVAKEGYKSLFKGAGANILRAVAGAGVLSGYDQLQIIFFGKAYSGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNZ7</accession>
    <name>A0A8T0HNZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG109400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11945" checksum="D6C55C33EC075E80" modified="2022-10-12" version="1">MPVHSNNATFTDGWGCTWPKDTMLISGTYYRRLASVGRDAGSFRYELLEDEPKAWNYSHLVVQSKVELVQYKTNKRNPRFKMSADTREAILSNVEERQAYNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP66</accession>
    <name>A0A8T0HP66_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG107100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035834203" evidence="2">
        <location>
            <begin position="22"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0572579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="5967" checksum="CE978F4DBD6CAE28" modified="2022-10-12" version="1">MHHQFLLLLQALRFLAANSSATESSPSSQTPSTKSSTPAAETTLSSNASDRVPQHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HPF5</accession>
    <name>A0A8T0HPF5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">COMM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG120000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HPF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017920">
        <property type="entry name" value="COMM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037354">
        <property type="entry name" value="Commd2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15857">
        <property type="entry name" value="COMM DOMAIN CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15857:SF0">
        <property type="entry name" value="COMM DOMAIN-CONTAINING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07258">
        <property type="entry name" value="COMM_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COMM" evidence="1">
        <location>
            <begin position="23"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14662" checksum="F8F4DB68486F3501" modified="2022-10-12" version="1">MFAQRHQELFGIVALCGTSYGRLDWRLDIQVVSRSVGQQAIPRFLLALQTTDGLKHLEADYTVLKDVCLQLEAALAESCSTRSWRFLCVFHRYPLLMVDLLVCTLNPRILLYKLMLSALCKNVKLQSGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRW9</accession>
    <name>A0A8T0HRW9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG199400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="17793" checksum="C7B373C7A0F1E9BC" modified="2022-10-12" version="1">MPLQMTLVSVRSDKHLWGSSKLTVFGCKLAFSPYLVSFPDSTNASIVPASFVVACAVFVGASSAVPMCGVDLGGEFCGRHRRCRQRRTLLLVSVEILGLQWSLHVFLNASLGLRRVASAELDNTQARGEGSRQSFTLNMFWVIDVIKNAAEAENFSQVGALALI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT19</accession>
    <name>A0A8T0HT19_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG224000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT19"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="79" mass="8678" checksum="0A095FBC75DD1A30" modified="2022-10-12" version="1">MSLSATLAGCPIGRRPLGLRIGISIQVAYIKQLHRVKLQSKSVNGERFSVTSNRVSVSLLRHGESDEVPECRPSWIFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVY1</accession>
    <name>A0A8T0HVY1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7869 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG296900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVY1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057191">
        <property type="entry name" value="DUF7869"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33153">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33153:SF3">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25273">
        <property type="entry name" value="DUF7869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7869" evidence="1">
        <location>
            <begin position="436"/>
            <end position="622"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF25273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="878" mass="100443" checksum="D493288A386704B8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX91</accession>
    <name>A0A8T0HX91_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G027000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX91"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF160">
        <property type="entry name" value="HXXXD-TYPE ACYL-TRANSFERASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="466" mass="52100" checksum="90A02C6ED30E9BDF" modified="2022-10-12" version="1">MADGRLLVENRVESKPFQVLSTSLVKPAVETPREKRWHAFSNLDIIWMPFYTQAMSVYKATEAGRDVGKRLRESLQRALTLFYPLAGRVVTESNEHGAAGMLCNDAGAVFVEASIDADLEEFQYENFQPSFRLTGMAEAGLGDYPRLPDDPAGRPALIVQMTHFRCGGITLAFNWAHPVADGFSGFHFLKSWAELARGEEVSLLPVHDRALVKPRKRLILSNPFTGGHPELQTSDGEQTLPQRNVEEKLQTTPMVQVVEITKQDIEEMKREVESGASGESPRLSRVCCVSAYLWRAIVKARELPGADLSRFWTLVEGRKKMSLPAGYFGNAIGGLYATTTVSNLLNKPLAYSASLVHASIQHCTKEWYLDLVDWIEAKKDWEYPGLVLGADHECGSSWQNRFPYYELDFGFGVPVCSARNANAAWDGFFVFLPSSQSPENYTAMLHATPDVMKKFLPMVHNFSYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY01</accession>
    <name>A0A8T0HY01_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G027600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY01"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11499" checksum="4CEC87909AA490A6" modified="2022-10-12" version="1">MEDFRMELKTIIILFIGVTVMRASCSSVCVTCLKVVERQSCCSASRSFPLKIENYGRTAAVGFIIPTREFNIFSMRSKQDEKCLLQAPFGRVLRAPSGLQSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYB8</accession>
    <name>A0A8T0HYB8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CNH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG339500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYB8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001180">
        <property type="entry name" value="CNH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032914">
        <property type="entry name" value="Vam6/VPS39/TRAP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019452">
        <property type="entry name" value="VPS39/TGF_beta_rcpt-assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019453">
        <property type="entry name" value="VPS39/TGFA1_Znf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894">
        <property type="entry name" value="CNH DOMAIN CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12894:SF43">
        <property type="entry name" value="VACUOLAR SORTING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10366">
        <property type="entry name" value="Vps39_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10367">
        <property type="entry name" value="zf-Vps39_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50219">
        <property type="entry name" value="CNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CNH" evidence="2">
        <location>
            <begin position="50"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="137"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="862"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="165"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1131" mass="122606" checksum="3837AD7D7439032D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZK5</accession>
    <name>A0A8T0HZK5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G063200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040:SF28">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 39-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040">
        <property type="entry name" value="PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="570"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="606"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="648"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="714"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="800"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1289"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1319"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1404"/>
            <end position="1424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1430"/>
            <end position="1451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1463"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1514"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="201"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="943"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="842"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="844"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="858"/>
            <end position="870"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="892"/>
            <end position="902"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0576207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1545" mass="173534" checksum="F86253C7DCFA44AB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0N5</accession>
    <name>A0A8T0I0N5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G084600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764">
        <property type="entry name" value="UBIQUITIN-LIKE-SPECIFIC PROTEASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="280"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="832"/>
            <end position="851"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="860"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="919"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="867"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="919"/>
            <end position="929"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0576499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="968" mass="110004" checksum="F83B82CBA0A41947" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I211</accession>
    <name>A0A8T0I211_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G101300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I211"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="203"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="569" mass="64968" checksum="25F7C778BCD48A95" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I338</accession>
    <name>A0A8T0I338_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G150800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I338"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd12087">
        <property type="entry name" value="TM_EGFR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="23355" checksum="2AAF2DD937FDA0F3" modified="2022-10-12" version="1">MGLSDNVTLFLSTLPQQQGVLDISNLDIGGPLPDWANNNISQLQLSELYLDKNRFNGTLNILAFAELSNISKSLKVLSLKDNMFTDVVTSEELVRVAGLTKINLQGNPYCNKSWTSEDDSRRCTFYCGHPCIYLPQKSNNMGWKVITMATSISSAVIVLVILGFGVILRRKQKHIRDLQKKIKEADINELRGLNTVNFELPQKTLLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4G9</accession>
    <name>A0A8T0I4G9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G169300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035941748" description="Secreted protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="88" mass="9184" checksum="9717B866233E3B51" modified="2022-10-12" version="1">MFGESRGLRSWRSALLCSALLYPCPPVPPPPSSCLSVGVDGDGAPTVAAIKANLKPQASASTHIHKLTHMHCTHTTTSSTARFSSANP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5F5</accession>
    <name>A0A8T0I5F5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G042900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5F5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6507" checksum="B518689D5564D07A" modified="2022-10-12" version="1">MLKAYRRFILYDNIISLTPSVLMQSVNQPVSLYARYFTSSRSVGDAQLAVRRCSGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6F2</accession>
    <name>A0A8T0I6F2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G069900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6F2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="106"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="34618" checksum="826A832423305CA2" modified="2022-10-12" version="1">MVTMSAMARTGPLFVAPLSSLCARRVAKASQKHGRLLKLESTCGARFGRVVCGLERSECVRSGVWLDRTLEALGRRSRKALPVRWEERRWTRAWTGQNLTWNEEQSPYETLGVERDADEDSIKGAYRRMAKQFHPDVYDERNGELKEGETPESYFIQIQAAYELLMNRDQRRQYDLDHRTNPLKASTAWMDWVIKKRKSFDQRGEMAASAWAEQQMREMNLKARRAARNKVDPEEERRILAREKAVSAANFENTIRRQALVLKKRDIMNRKAREEAQMRLVQQLLEAEGLELDDEQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8H7</accession>
    <name>A0A8T0I8H7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glycosyltransferase family 92 protein</fullName>
            <ecNumber evidence="8">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G132300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the glycosyltransferase 92 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="8"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8H7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008166">
        <property type="entry name" value="Glyco_transf_92"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21461:SF69">
        <property type="entry name" value="GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01697">
        <property type="entry name" value="Glyco_transf_92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0579894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="575" mass="65478" checksum="6F3504949597167C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9L0</accession>
    <name>A0A8T0I9L0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alpha/beta hydrolase fold-3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G168000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9L0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050466">
        <property type="entry name" value="Carboxylest/Gibb_receptor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024:SF24">
        <property type="entry name" value="ALPHA_BETA HYDROLASE FOLD-3 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23024">
        <property type="entry name" value="ARYLACETAMIDE DEACETYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alpha/beta hydrolase fold-3" evidence="2">
        <location>
            <begin position="170"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="47328" checksum="3E4DC4B31EC94470" modified="2022-10-12" version="1">MLQRSGDTSINKSSWPSQQSTLDVPTTNLTCVETPRLNLTKRIRFLKSTLRASCEESGSEVKQLHLHRNSEDFKRAACCTVADAFVMDVEQHREPSDEGVQSDDGSENRALANMFEQTVSANATPVDGVATFDAVVDSALGVWVRLFVPTQLDGGSKESGSKSAETMPLVLYFHGGGFVALTPDVALYDQFCRRLAAHSHAVVVSVCYRLAPEHKFPAAYDDSFTALEWLNSEAAKSLLPPNVDLSRTFLCGDSAGGNIVHHLAVQVAESKDLGPNLKLAGLVLIQPFFGGEERTPAEVRMQNPAILSIDHCDFAWKAFLPPDATRDHPAAHVFGPHSKDLRNVAMPPALIIVGGLDILQDWEMRYAEGMKEAGKDVVVCFYEDGIHVFCLLDQTAPTADKMMLDVASFIATHSQFPTPTNPVASHSQFVIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9R8</accession>
    <name>A0A8T0I9R8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G172900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9R8"/>
    <dbReference type="OrthoDB" id="3222at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00333">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034294">
        <property type="entry name" value="Aquaporin_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724:SF13">
        <property type="entry name" value="AQUAPORIN NIP1-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45724">
        <property type="entry name" value="AQUAPORIN NIP2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0580434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="290" mass="30337" checksum="4500FA05AFF73DBD" modified="2022-10-12" version="1">MAEIKIRMPGAVPSADEYSTAVTAGNKVLQDPSPNRSQDAQESSQQGRYRAWVTALRPHTTLLQKLIAEVISTFILVFTGCGAAMVNEISNGKVTAVGISLAFGLVVTIMIYSVGHISGAHMNPAVTLAFAVAKHFPWTQVPLYIGAQCGGSISAAFMLRWILHPAASEGATLPFGTDVQSFLLEIVITFVLMFVVAAVATDTRACGELAGIAIGSAVALNALMAGPISGASMNPARSIGPAVASGNYRALWVYVAGPIIGSITGMLAYNCIRLPDTGVQGDKPAKSFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA26</accession>
    <name>A0A8T0IA26_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G124000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA26"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000364">
        <property type="entry name" value="heterogeneous nuclear ribonucleoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000519">
        <property type="entry name" value="heterogeneous nuclear ribonucleoprotein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001502">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="103"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="294"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="442"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="48013" checksum="E3DBAFD5A987D0D1" modified="2022-10-12" version="1">MERNSGDHGMNLGSRKLVVLGIPWDIDTEGLRQYMLKFGELDDVIVMKDRSTGRSRGFGYVTFAAVEDAKKAVSTQHSLNGRMLEVKVATPKEEMKPPAKKITRVFVARIPPSVTDENFRSYFEKYGTLTDAYMPKDQGSKAHRGIGFVTFENPESVDRLMNETHELGGSTIAVDRATPKEDGNKSWGRGFHGGNSNSGSNAGSGAYGAYGVYTAARFGGFGGGFGAYDYAGSGLGNDLGPSGGLSSAYGGGNSWPPAPPGGGYGGPGLGIPGGGSGSYGSGGPPVPPLRGLGTKIFVGRLPPEANAEDLRRYFNNFGRISDVYVPKDAKKTSHRGFGFVTFSDEGAAERVALRSHEILGHQIAVDRAAPQDEMSNISYMNSVGSLGSLSQGAGGPMRGSNAPLQGSGYGSLSCNLDSSGWGGYGGVGGFSFQTPDSGLRTPDSRSSRSEPRYRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBX6</accession>
    <name>A0A8T0IBX6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G173200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBX6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36004">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36004:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="177" mass="19010" checksum="DD24B39A696074CA" modified="2022-10-12" version="1">MAAMATAAGMARLLTTAPSTSCSSRSAAPAARPTSSFSPRRHQSLMPTSGRRLGSLHLANARNVPAERKSVTVTPTEPEMSPADVKVYEETCAKLEGVQPDFWEGSGWNALGWTIQYMWVFGIVVSIVACITAVRTYNLGATDFKNTEVFKEAIEFQTDAAESSGLSAFDESNQEAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IC36</accession>
    <name>A0A8T0IC36_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G177100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the Nibrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IC36"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030870">
        <property type="term" value="C:Mre11 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007095">
        <property type="term" value="P:mitotic G2 DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd22667">
        <property type="entry name" value="FHA_NBN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.20:FF:000017">
        <property type="entry name" value="Nibrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040227">
        <property type="entry name" value="Nibrin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162:SF0">
        <property type="entry name" value="NIBRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12162">
        <property type="entry name" value="NIBRIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SMAD/FHA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="10">
        <location>
            <begin position="25"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="332"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="404"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="496"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="343"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0580489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="709" mass="78322" checksum="CCE4146FC3F05A78" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID88</accession>
    <name>A0A8T0ID88_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G205600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="9008" checksum="DAA44968C9FE21FA" modified="2022-10-12" version="1" fragment="single">MPRNTYTKTELNQKPSTSCSRLEKLKPNYLFSSRTPPHDLHLPRLQTPALPNQPTSLTAPNSKLHLYGSANTTSSPVPKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFL6</accession>
    <name>A0A8T0IFL6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Sjoegren syndrome nuclear autoantigen 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G038500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033362">
        <property type="entry name" value="SSNA1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661:SF1">
        <property type="entry name" value="MICROTUBULE NUCLEATION FACTOR SSNA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28661">
        <property type="entry name" value="SJOEGREN SYNDROME NUCLEAR AUTOANTIGEN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="177" mass="19796" checksum="D78EEBEAB313699E" modified="2022-10-12" version="1">MRTDAKDLALSVFQRQKDRCVRPPDLAFAVSRRQKGRCIRPPVGELPKEASCEDGPPVTPGMAAQGSAAMNVYNNELTHLDLGIEELREKKEKIKKVMQLEEEEKANIQREVAALAKRLAAIDKSLSQKYAYVEEYDKTIQDVESAYCKILESSQALLHVLKTENSTQVPPVAQSAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFP7</accession>
    <name>A0A8T0IFP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G269600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009199">
        <property type="entry name" value="PhoPQ-act_pathogen-rel_PqaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31497">
        <property type="entry name" value="AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31497:SF0">
        <property type="entry name" value="AUTOCRINE PROLIFERATION REPRESSOR PROTEIN A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10142">
        <property type="entry name" value="PhoPQ_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="581" mass="64831" checksum="B5F12B3DA8E18D5F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGL1</accession>
    <name>A0A8T0IGL1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UBC core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G030800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the ubiquitin-conjugating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGL1"/>
    <dbReference type="OrthoDB" id="6600758at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd23798">
        <property type="entry name" value="UBCc_UBE2I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000038">
        <property type="entry name" value="SUMO-conjugating enzyme SCE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050113">
        <property type="entry name" value="Ub_conjugating_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023313">
        <property type="entry name" value="UBQ-conjugating_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24067">
        <property type="entry name" value="UBIQUITIN-CONJUGATING ENZYME E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00183">
        <property type="entry name" value="UBC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="5">
        <location>
            <begin position="5"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" description="Glycyl thioester intermediate" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0582059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="160" mass="17913" checksum="CA60CF9E0B9F59BC" modified="2022-10-12" version="1">MSGGIARGRLAEERKAWRKNHPHGFVARPETGADGALNLMIWQCTLPGKVGTDWEGGFYPVAIHFSEDYPSKPPKCKFPQGFFHPNVYPSGTVCLSILNEDSGWRPAITVKQILVGIQELLDAPNPADPAQTEAYQLFIQDPVEYKRRVRQQAKQYPPPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK04</accession>
    <name>A0A8T0IK04_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G085000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK04"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="CDD" id="cd02989">
        <property type="entry name" value="Phd_like_TxnDC9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21148">
        <property type="entry name" value="THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="74"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="215" mass="24589" checksum="1127481865482527" modified="2022-10-12" version="1">MAAPVAIQKALEDSLATVAKAVEDQLDDELAKLDKLEEDDLEKLRERRIQQMKKQATMRQQWLAQGHGDYQEIFSEKDFFAKVKTSDRVVCHFYRENWPCKVMDKHLLDLSKQHLETKFLKINAEKSPFLTERLKIFMLPTLALVKKGKVEDYVVGFDELGGKDDFSTEELEDRLAKSAVLHGPEGRVMRPVAAQAKRSVRQGSSSYGDNSDDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK96</accession>
    <name>A0A8T0IK96_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dehydrin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G136300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="176" mass="18213" checksum="46EBA2852ED08022" modified="2022-10-12" version="1">MDGQDYEEDGRLGPAEKIALPSEDTHTSQPERDLQPGDPNLVGGAPPAEKKGMADKVKGLFGGMKKGHHEADTDSAVGSGVGHTPDASPYGTPDGDDYNGRSLDPTGAPAGASEFRSEDATDDGVPHPTDPEGVTNDQGGAALTDEKGNLKPGPHQKAVKREGIVSKIKDKLHGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN66</accession>
    <name>A0A8T0IN66_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">THO complex subunit 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G168800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the THOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000445">
        <property type="term" value="C:THO complex part of transcription export complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006406">
        <property type="term" value="P:mRNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040007">
        <property type="entry name" value="Tho2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021418">
        <property type="entry name" value="THO_THOC2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021726">
        <property type="entry name" value="THO_THOC2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032302">
        <property type="entry name" value="THOC2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597:SF0">
        <property type="entry name" value="THO COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21597">
        <property type="entry name" value="THO2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11262">
        <property type="entry name" value="Tho2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11732">
        <property type="entry name" value="Thoc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16134">
        <property type="entry name" value="THOC2_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="12"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunit 2 N-terminal" evidence="9">
        <location>
            <begin position="434"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 N-terminal" evidence="8">
        <location>
            <begin position="587"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="domain" description="THO complex subunitTHOC2 C-terminal" evidence="7">
        <location>
            <begin position="914"/>
            <end position="1209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="862"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1237"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1792"/>
            <end position="1930"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="937"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1283"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1321"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1357"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1376"/>
            <end position="1387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1424"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1452"/>
            <end position="1493"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1519"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1559"/>
            <end position="1696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="1704"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1725"/>
            <end position="1735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1746"/>
            <end position="1758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1792"/>
            <end position="1810"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1852"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1890"/>
            <end position="1923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1930" mass="216611" checksum="1B0B2B9A04F8D6DE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ING6</accession>
    <name>A0A8T0ING6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G206000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ING6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="120" mass="13265" checksum="37096B98FBC93099" modified="2022-10-12" version="1">MPITCTPQLVSSPQIVQVGRVEELKSSRIMWAPPQNKLTLNFDHHNSKNITNPIASRSRFRAITHIGLRAIYALSTANVHIIAGNASLTKGSSKHEEFLTALGSDFSISMEVENEKHRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INZ7</accession>
    <name>A0A8T0INZ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G244000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INZ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0584912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7213" checksum="1DFA6DC24ECC0C5B" modified="2022-10-12" version="1">MNATTESRIKLSGIQRHTEFFDSELQSAWARCRHLNVEDSATGQGADVNFSIVVYWSYECEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPH0</accession>
    <name>A0A8T0IPH0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G027100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056694">
        <property type="entry name" value="DUF7792"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46168">
        <property type="entry name" value="ARMADILLO REPEAT ONLY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46168:SF1">
        <property type="entry name" value="ARMADILLO REPEAT ONLY 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25055">
        <property type="entry name" value="DUF7792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816967" description="Protein kinase domain-containing protein" evidence="7">
        <location>
            <begin position="17"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="237"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0585644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1344" mass="149032" checksum="0A4F656D9F351ACA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPQ5</accession>
    <name>A0A8T0IPQ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Mitochondrial pyruvate carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G234600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Mediates the uptake of pyruvate into mitochondria.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Mitochondrion inner membrane</location>
            <topology evidence="1 9">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPQ5"/>
    <dbReference type="OrthoDB" id="1697690at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006850">
        <property type="term" value="P:pyruvate import into mitochondria"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005336">
        <property type="entry name" value="MPC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03650">
        <property type="entry name" value="MPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 9" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5 9" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0584791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12939" checksum="3EC814396D38509B" modified="2022-10-12" version="1">MATSLRAFWNSPVGPKTIHFWGPIANFGFVLAGLVDIQKPPEMISGRMTGVMCAYSASYMRFAWMVRPQNLLLCGVHGCNEVVQLYQLQRWGRWRYSSTPDEELSTYSSQEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQV0</accession>
    <name>A0A8T0IQV0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G249800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000121">
        <property type="entry name" value="Prostaglandin reductase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051397">
        <property type="entry name" value="Zn-ADH-like_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677:SF3">
        <property type="entry name" value="PROSTAGLANDIN REDUCTASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43677">
        <property type="entry name" value="SHORT-CHAIN DEHYDROGENASE/REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Enoyl reductase (ER)" evidence="2">
        <location>
            <begin position="292"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0584998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="633" mass="67882" checksum="DA99D01E6E2B316A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQW6</accession>
    <name>A0A8T0IQW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G251200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00198">
        <property type="entry name" value="vWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015894">
        <property type="entry name" value="Guanylate-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796">
        <property type="entry name" value="URG4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22796:SF1">
        <property type="entry name" value="VWFA DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02263">
        <property type="entry name" value="GBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="1831"/>
            <end position="2030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="114"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2034" mass="229147" checksum="4A094C0288758C5E" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISB0</accession>
    <name>A0A8T0ISB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G029000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="16694" checksum="869C29E97216E6D5" modified="2022-10-12" version="1">MSPGVRHGIDRKIHKSVRGVKREGSEPVWGRGKVATPSGQVSRHGGGGHGDRGDKRGAAGSTGSRCALACWCTCFISQVCPVGPPRALPPGTCHLPTSLTPPLARPHSLSLHSLSLLASLSSLARALNPSPQSPSPSPLRSLTGLPYISSTSPACAQLDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITT6</accession>
    <name>A0A8T0ITT6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">pyruvate kinase</fullName>
            <ecNumber evidence="4">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G069300</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000010">
        <property type="entry name" value="Pyruvate kinase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000051">
        <property type="entry name" value="Pyruvate kinase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF011314">
        <property type="entry name" value="PRK14725.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="14">
        <location>
            <begin position="380"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="14">
        <location>
            <begin position="571"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="309"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="88"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="310"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0586161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="873" mass="94310" checksum="F5F5670BF55AAAC4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX99</accession>
    <name>A0A8T0IX99_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G133400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="40"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="208" mass="21898" checksum="7F7F84D533B3EBD0" modified="2022-10-12" version="1">MCLRTTMVPAVLRAGASAPSGGQLFHMQGLGNIPQTQHTPPRSSWSIFSSSSSSSSLPPPPLVPALLEGPCPSFALVSPSSSLLTGLVSFKIAFFALLFPEGLAGPLPLPEGEGPATGVVASGCTYPPSEPESESVISASLPMVNNYLVSGRLRGHKMDECMLKSHGLNRGSSTQLIIPGANDLFEQRHEVETSADILDSRFHNFLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXC0</accession>
    <name>A0A8T0IXC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G239200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12042" checksum="5693E99862DB796C" modified="2022-10-12" version="1">MFSELPYSKSGEDNRKIACTIALLYSTSERIPVLDLCRALGSSKMRPFTLGSANTASLHRVTSILLSVVAYSCHLGIQRSLTDCSSRSSTDNLKNRGSIFNDEFSLFLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZ08</accession>
    <name>A0A8T0IZ08_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BURP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G177800</name>
        <name evidence="4" type="ORF">KC19_2G177900</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZ08"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044816">
        <property type="entry name" value="BURP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004873">
        <property type="entry name" value="BURP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31236">
        <property type="entry name" value="BURP DOMAIN PROTEIN USPL1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31236:SF45">
        <property type="entry name" value="BURP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03181">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01045">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51277">
        <property type="entry name" value="BURP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036435089" description="BURP domain-containing protein" evidence="1">
        <location>
            <begin position="31"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="BURP" evidence="2">
        <location>
            <begin position="97"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0587614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="325" mass="35326" checksum="86892253B4991AFF" modified="2022-10-12" version="1">MFHCSHNMATYNFRMLIMFLFFSATSMAYATSRPLAEVTSSSPDQLIREVCSPQSLLTCNNYDNAEPVYVAADEGAEAAGILRDRSIVTINDLQEDFFLESSLVEGRKTTVHNYLYDPAPSRAFLSPTDATTLPTLTTYNTLDIMRFYGVARDSNMATSIATAAYLCGSAALPGEARSCAASTDALAAFVAAQLGNNVRVYATKGAPTSTSTSNMKAPVTIMKVAKGSVEEGRKIVVCHHLAFPSALYYCHAVTGTKVVQATLKTEGRYHQRAHIKAMAVCHLNTELWLSRHPAFKALKIARGEEACHFLVGNDLLFTRVAPIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0F1</accession>
    <name>A0A8T0J0F1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G262200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0F1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11653" checksum="006C4B43AA5E3302" modified="2022-10-12" version="1" fragment="single">VIKRLFEKAYPLLGPLDADSVAKQRSNVPNLRSSKRVQTRSPRLQPVFLAPLHSILHEGLCSPMRMRGLLTTPLPPRFSAHLRYRPSSTALCRTSEVRRYFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J178</accession>
    <name>A0A8T0J178_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G267200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J178"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="390" mass="44742" checksum="493AF7CAE475456A" modified="2022-10-12" version="1">MAEELDAKVWSELPAEILERVLRWLPFSTLCKFRAVCKYWNTLPTVRAEQPYILDIPCNTKKDYVTCLRYCCLYSPTANTWDFIDLSFLPQRMTQLSSCPCYWTPQIERFCSDGGLLCVWGKLLERDLRDYFSDIIPHYTILVCNPLTKRCKLLPPFDFTYQGSIDLVMKRESSGEYKIFAVALAYTGEPGLYLRHYMYDSASDSWMLLLDLKRDCSDVSLLRFGSITFDGVYYCVSGGGRQPYDLYAYNIKQNSWIAAGVKMKLNPKTTRVLFVVSNARLLLIASILEEKLYFSINQVDLRRTETMCSPADYVSLPANFTWKRGVALAYRDSIIFASESKCRFMAVDLLSLSADLKELKSITPMSVIPTSERYTQTNMANASFDVQATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1D9</accession>
    <name>A0A8T0J1D9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein ARV</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G280200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.</text>
    </comment>
    <comment type="function">
        <text evidence="10">Regulates also the sphingolipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Endoplasmic reticulum membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the ARV1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1D9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007290">
        <property type="entry name" value="Arv1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04161">
        <property type="entry name" value="Arv1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0746">Sphingolipid metabolism</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU368065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6525" checksum="FECAE1BE2108DE99" modified="2022-10-12" version="1">MCACGTPVAAVYVDHAPGNIRLSECAQCGFGADEYVECEMMVIIRFALLVLTRISRSSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J429</accession>
    <name>A0A8T0J429_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="5" type="ORF">KC19_1G049400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG0589806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Chromosome 1"/>
    </dbReference>
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        <property type="term" value="C:NuA4 histone acetyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EAF1A/B"/>
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        <property type="entry name" value="HSA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46774">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN EAF1 A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46774:SF3">
        <property type="entry name" value="CHROMATIN MODIFICATION-RELATED PROTEIN EAF1 A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07529">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13921">
        <property type="entry name" value="Myb_DNA-bind_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00573">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51204">
        <property type="entry name" value="HSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="599"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="3">
        <location>
            <begin position="1131"/>
            <end position="1182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="280"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="500"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="774"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="1219"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="1301"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="2">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
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            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
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            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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            <end position="837"/>
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        <location>
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        </location>
    </feature>
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        </location>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <end position="1040"/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
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            <end position="1583"/>
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        <location>
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    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
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            <end position="1793"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
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            <end position="1810"/>
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    </feature>
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            <begin position="1842"/>
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        </location>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2150"/>
            <end position="2165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2289" mass="236668" checksum="55A98AF012A8C6E7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5G3</accession>
    <name>A0A8T0J5G3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ARM repeat superfamily protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G086500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
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            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
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            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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        <location>
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        <location>
            <begin position="234"/>
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        <location>
            <begin position="251"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG0590279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5G6</accession>
    <name>A0A8T0J5G6_CERPU</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="1" type="ORF">KC19_1G065700</name>
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    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
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        <lineage>
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            <taxon>Bryophytina</taxon>
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            <taxon>Ceratodon</taxon>
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        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
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                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12025" checksum="787355B4CDE4DF70" modified="2022-10-12" version="1">MGVIPCTGWHILVLTCVVCREEVHYLVMPCRGCVWCLFWLRGSTGASCSSSFALLGVCRMFDIGARQGYSLLSAALISWLNQTATSNSSNQVCLSTCKNSLRQSVKVDVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6U8</accession>
    <name>A0A8T0J6U8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G105700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6U8"/>
    <dbReference type="OrthoDB" id="18139at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045047">
        <property type="term" value="P:protein targeting to ER"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012098">
        <property type="entry name" value="SND3_fun"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28112:SF1">
        <property type="entry name" value="SRP-INDEPENDENT TARGETING PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10032">
        <property type="entry name" value="Pho88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="201"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="24664" checksum="B1A6B71E993F4998" modified="2022-10-12" version="1">MGFSWKVLVGPAMLVAMKVLKIDYDVPHNILIIRTLYALSQLALFAGLYVIYQRITQDGDEKKTVKVKVTSPAGATEEQVMTYKDYDMSELQKLVKSFGVGAAMTIGIHVYMAVVPALLLQMVTQPITLYDHALFSLYILKKDASKDKKLKRPFPNDSPMAKLEAMKKELAEEEEQRKKKDEDSQPTPVIEDSATTTSHEPVSRAERRPRVRDETDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8U2</accession>
    <name>A0A8T0J8U2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RCC1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G171900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8U2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.30">
        <property type="entry name" value="Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058923">
        <property type="entry name" value="RCC1-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000408">
        <property type="entry name" value="Reg_chr_condens"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051210">
        <property type="entry name" value="Ub_ligase/GEF_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870">
        <property type="entry name" value="REGULATOR OF CHROMOSOME CONDENSATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22870:SF360">
        <property type="entry name" value="ULTRAVIOLET-B RECEPTOR UVR8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00415">
        <property type="entry name" value="RCC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25390">
        <property type="entry name" value="WD40_RLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00633">
        <property type="entry name" value="RCCNDNSATION"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="RCC1/BLIP-II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00626">
        <property type="entry name" value="RCC1_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50012">
        <property type="entry name" value="RCC1_3"/>
        <property type="match status" value="7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="RCC1-like" evidence="4">
        <location>
            <begin position="9"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="33"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="86"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="190"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="242"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="294"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="repeat" description="RCC1" evidence="2">
        <location>
            <begin position="346"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="436"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="443"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF25390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0591389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="459" mass="49330" checksum="9E5635EBF561B096" modified="2022-10-12" version="1">MEEDKAASSEGPRKRVVAVSAGASHTVALLSGDVVCSWGRAEDGQLGHGDAEERHLPLIISALDDCEISSITCGADHTTARSESTKTVYSWGWGDFGRLGHGNSSDLFVPRAIRGLRGLEIRQIACGDSHCLAITGDGEVHSWGRNQNGQLGLGHTEDVLVPNKVAAFEGIAVKMLAAGAEHTAAVTESGKLYGWGWGRYGNLGLGDRNDRLVPGEVAAVPGEKMNLVACGWRHTIAVADSGKLFTFGWSKYGQLGHGDYEDHLVPFQVQALKNKTIQAVSGGWRHTVALDEDGQLYGWGWNKFGQVGCGNTDDQNSPKLVTGIDNQKVTQVTCGWRHTVAITDRGNVYSWGRGTSGQLGHGDAVDRCVPKRVEALSSDGLACQNIERSPSRTCATSNWISPAERYAVVPDETMGPLTNRLHQTNYMDDQAVFVPDASTGSDRTSHLPDSETKRLRTAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA49</accession>
    <name>A0A8T0JA49_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PGR5-like protein 1A, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G205300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA49"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016730">
        <property type="term" value="F:oxidoreductase activity, acting on iron-sulfur proteins as donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009773">
        <property type="term" value="P:photosynthetic electron transport in photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039987">
        <property type="entry name" value="PGRL1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31032:SF1">
        <property type="entry name" value="PGR5-LIKE PROTEIN 1B, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="350" mass="37889" checksum="581E723E90723D56" modified="2022-10-12" version="1">MEMVAGLAMPASTSKLMVCSCSGRNVQAVRGLGLGLRGGVVGRRWVGVVEGRGRRGVVVMQAGEGKKGSEVVPGEESDLDDKILPYCDIKGKGGKKTLGEMEQEFLEALQSFYFDSTPIMSNEEFDNLKEELTWEGSSVVILSSDEQRFLEASLSYAAGKPILNDQEFDNLKMKLKMKGSKVAIAGPRCSLRSKKVVSDATVDYLKMTALNLPAALIALGLVFFLDDITGFEITYLLELPEPYSFLFTWFIVLPVTFLIAQSITNLVLKDALILTGPCPNCGRGTNSYFGSILTIPSAGKENTVKCEGCSSNMIFNVETRLITLDDSPPSAPKKPVRTPKPASEKVSTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAH6</accession>
    <name>A0A8T0JAH6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">C2 and GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G237900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044511">
        <property type="entry name" value="At1g03370/At5g50170-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031968">
        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296">
        <property type="entry name" value="BNAA05G37250D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296:SF8">
        <property type="entry name" value="OS06G0297800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00360">
        <property type="entry name" value="C2DOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00568">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="298"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="6">
        <location>
            <begin position="569"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="7">
        <location>
            <begin position="894"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="162"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="162"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="238"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0592266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1080" mass="121303" checksum="933770420F146803" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB62</accession>
    <name>A0A8T0JB62_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">NADH:flavin oxidoreductase/NADH oxidase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G259800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02933">
        <property type="entry name" value="OYE_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000073">
        <property type="entry name" value="12-oxophytodienoate reductase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="NADH OXIDOREDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893:SF91">
        <property type="entry name" value="NADPH DEHYDROGENASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH:flavin oxidoreductase/NADH oxidase N-terminal" evidence="6">
        <location>
            <begin position="33"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0592526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="43643" checksum="5C60D4BC0D292737" modified="2022-10-12" version="1">MGHEVAASVLEEAGNGGGDAVEFGTMPLLSSYQLGSFKLSHRVVHGPLTRCRSYGCVPQPSHAGLYYAQRATPGGLLIAEATGVSETSNGYPHTPGIWTQEQVEAWKPIVKAVHDKGGVFFCQIWHVGRVSHTSYQPNAAAPISSTNQAVKSEKIYLPSADGAVDCSIPRALETDEVAEYVEHFRKAARNCIEAGFDGVEIHGSHGYLIDQFLKDGINDRTDKYGGSMENRCRFMVEVVEAVTKEIGADRVGIKISPFSHSYDASDSDPTKLSVYIAETLNRYNLLYLLGVEGRDSEAKESIWPMRKAYKGNFFVGAGFNAEEGNEAIKSGKADMVAYGRLFLANPDLVKRFALNAPLNKYNRETFYTQDPVIGYTDYPFLEDALESQLLDSAAGDTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCI9</accession>
    <name>A0A8T0JCI9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G267500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCI9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042548">
        <property type="term" value="P:regulation of photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08866">
        <property type="entry name" value="SRPBCC_11"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005031">
        <property type="entry name" value="COQ10_START"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060:SF2">
        <property type="entry name" value="OS03G0837900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34060">
        <property type="entry name" value="POLYKETIDE CYCLASE / DEHYDRASE AND LIPID TRANSPORT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03364">
        <property type="entry name" value="Polyketide_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="2">
        <location>
            <begin position="245"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="Coenzyme Q-binding protein COQ10 START" evidence="2">
        <location>
            <begin position="461"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="609"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="837" mass="94506" checksum="F7606C1BD12EBBBE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G370</accession>
    <name>A0A8T0G370_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G019700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G370"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044550">
        <property type="term" value="P:secondary metabolite biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000126">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF4">
        <property type="entry name" value="OS09G0441700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0553550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="517" mass="57446" checksum="D1416C44A82BA556" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3F9</accession>
    <name>A0A8T0G3F9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Morc S5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G036300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MORC ATPase protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3F9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031349">
        <property type="term" value="P:positive regulation of defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000075">
        <property type="entry name" value="MORC family CW-type zinc finger protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045261">
        <property type="entry name" value="MORC_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041006">
        <property type="entry name" value="Morc_S5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336:SF80">
        <property type="entry name" value="PROTEIN MICRORCHIDIA 7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23336">
        <property type="entry name" value="ZINC FINGER CW-TYPE COILED-COIL DOMAIN PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17942">
        <property type="entry name" value="Morc6_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Morc S5" evidence="12">
        <location>
            <begin position="395"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="554"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="27"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="629"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0553753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="775" mass="86668" checksum="698F7BFAB75E993B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7M6</accession>
    <name>A0A8T0G7M6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G123400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7M6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035725647" evidence="1">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12850" checksum="F2BBE6532A6D122E" modified="2022-10-12" version="1">MISVRKALEFVNMSMLLQLVAGQNKLLAGQNRILELLEEARLYRAQPLQQIADQANSTMIWTTRYVCQKPSPISKFLKPIIHIVSNEDHELAAAEHGRYVIWKDPRTVHSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G914</accession>
    <name>A0A8T0G914_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G156300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G914"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12545" checksum="20A20D6B045D5296" modified="2022-10-12" version="1">MFVQLPFSLLQQGFFKMRTRPCPSALCPPNRTMKQCSNCEAVPYICNLLCSPKGPKWSSNLFHRQICKGGQNMLHLACSDMMLKAHKMHRNMVLDLDMRFGKLDIIVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G952</accession>
    <name>A0A8T0G952_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">E3 ubiquitin-protein ligase FANCL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G135900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G952"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043240">
        <property type="term" value="C:Fanconi anaemia nuclear complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006513">
        <property type="term" value="P:protein monoubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd23832">
        <property type="entry name" value="DRWD-C_FANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23831">
        <property type="entry name" value="DRWD-N_FANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23786">
        <property type="entry name" value="ELF_FANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16490">
        <property type="entry name" value="RING-CH-C4HC3_FANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.20">
        <property type="entry name" value="RWD domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026848">
        <property type="entry name" value="Fancl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026850">
        <property type="entry name" value="FANCL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043898">
        <property type="entry name" value="FANCL_d2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044037">
        <property type="entry name" value="FANCL_d3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043003">
        <property type="entry name" value="FANCL_d3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019162">
        <property type="entry name" value="FancL_WD-rpt_cont_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13206:SF0">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE FANCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13206">
        <property type="entry name" value="UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11793">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09765">
        <property type="entry name" value="FANCL_d1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18890">
        <property type="entry name" value="FANCL_d2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18891">
        <property type="entry name" value="FANCL_d3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01197">
        <property type="entry name" value="FANCL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fanconi anemia complex subunit FancL WD-repeat containing" evidence="1">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="FANCL UBC-like" evidence="3">
        <location>
            <begin position="100"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="FANCL UBC-like" evidence="4">
        <location>
            <begin position="190"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FANCL C-terminal" evidence="2">
        <location>
            <begin position="296"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0554997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="373" mass="42451" checksum="12312EEE1CA549B9" modified="2022-10-12" version="1">MATVPTVLPLNVDFTAYQVLLPVKGKEFVVGVHNVEAGKSLSVAKIDCCSELRKLLTGFEHIIQERLNQSMDVATFVEELKDVLEHILLAQPQVKLPPAAFYGRIYSEIEEIGWEHIAWVAPTFMSIHLRFFDRAIREHLVQIQLSPDYPEREPSCNADLPIALEIQWRAGGRLKDILSQFEQAAEKYQDFWTVMEDIDKHVWVMEPEHPSRSNCFRRIALGGHCSLCITVEPFSPRMLPEYRFFGSDTAVDPLRLRMSNNMDCWKLERLLRENLEDVLGITFPSPQDSDRDDVSSECIICYSYRLLDGKEGASEKGSVPDRVCDNGSCGRPFHTSCLAEWLRSLPTTRQSFDVLFGACPHCSHPVIVKCSFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9H3</accession>
    <name>A0A8T0G9H3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fe2OG dioxygenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G006700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9H3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF236">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035763567" description="Fe2OG dioxygenase domain-containing protein" evidence="9">
        <location>
            <begin position="17"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="10">
        <location>
            <begin position="174"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="43"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0555833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="274" mass="29802" checksum="ED98D25414B2FCC7" modified="2022-10-12" version="1">MRASTAAMMMILQLLSSPLILIRGPDAALQNPPRRLSSLRMVGAGAAGKSTHTSTAQKPSNNKRKSSASTPKLPELQAWPAVAPKPALRRELLHSTHLFTVPEFLSDKECEAFIRSAEARGLEHQGSGGPAKGEAFRDNERLSDYNVELADMLWQAGLRELFDGVVVGRKVAVGLNPNIRLYRYGQGQRFGPHYDESVDIDGGGATEFTLLVYLTGGLRGGETVFYDRRKIVAEVAPAAGMALFHIHGARCLLHEAKAVLKGIKYVLRSDVVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9X8</accession>
    <name>A0A8T0G9X8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G018600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9X8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032787">
        <property type="term" value="P:monocarboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050259">
        <property type="entry name" value="SDR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879">
        <property type="entry name" value="3-OXOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42879:SF2">
        <property type="entry name" value="3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0555993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11454" checksum="F833C63849B4D529" modified="2022-10-12" version="1">MPAAPKLMMKKRKGRIINISSVVGVTGNVGQANYAAAKAGVIGFTKSVAREYAGRNITLYVRIHSAGECCGSHTARGPKFYRNTVLLRFLINNYQLSGCDFSTQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBI3</accession>
    <name>A0A8T0GBI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="19">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_11G060400</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="19">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="function">
        <text evidence="18">This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17 19">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="19">Membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 19">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="19"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005516">
        <property type="term" value="F:calmodulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000036">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000039">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000006">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000013">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00121">
        <property type="entry name" value="NAKATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0007">Acetylation</keyword>
    <keyword evidence="9 19" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 19" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 19" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="11" id="KW-0112">Calmodulin-binding</keyword>
    <keyword evidence="15 19" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="16 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 19" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 19" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="365"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="935"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="968"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="20">
        <location>
            <begin position="84"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00053300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0556531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1068" mass="117092" checksum="9D588961F390C6FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ74</accession>
    <name>A0A8T0GJ74_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G115100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ74"/>
    <dbReference type="OrthoDB" id="540492at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038956">
        <property type="entry name" value="LEA_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000389">
        <property type="entry name" value="Small_hydrophilic_seed_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671">
        <property type="entry name" value="EM-LIKE PROTEIN GEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671:SF19">
        <property type="entry name" value="EMBRYONIC ABUNDANT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00477">
        <property type="entry name" value="LEA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="13057" checksum="94549E68194A6FEC" modified="2022-10-12" version="1">MAPTHHEDEGPMSEEAQFRVKYGGTKGGLTRGDGEHPEPSEEDVHAKGGLSKEAQERIVEGGRKGGQTRAAQMGREGYQEMGRKGGLATKDKSGEEAAREKGIEIDEAKYKTKSELSDVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJS0</accession>
    <name>A0A8T0GJS0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G090800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CSC1 (TC 1.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJS0"/>
    <dbReference type="OrthoDB" id="1689567at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003864">
        <property type="entry name" value="CSC1/OSCA1-like_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027815">
        <property type="entry name" value="CSC1/OSCA1-like_cyt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032880">
        <property type="entry name" value="CSC1/OSCA1-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF141">
        <property type="entry name" value="OS01G0950900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14703">
        <property type="entry name" value="PHM7_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02714">
        <property type="entry name" value="RSN1_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13967">
        <property type="entry name" value="RSN1_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="565"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like N-terminal transmembrane" evidence="10">
        <location>
            <begin position="6"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like cytosolic" evidence="11">
        <location>
            <begin position="197"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="CSC1/OSCA1-like 7TM region" evidence="9">
        <location>
            <begin position="368"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="739" mass="84512" checksum="E5CA54E9389B9D17" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJV1</accession>
    <name>A0A8T0GJV1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Hexosyltransferase</fullName>
            <ecNumber evidence="6">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G056500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050748">
        <property type="entry name" value="Glycosyltrans_8_dom-fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13778">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13778:SF47">
        <property type="entry name" value="LIPOPOLYSACCHARIDE 1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="19"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="471" mass="54466" checksum="A1CB472BC3ABFF02" modified="2022-10-12" version="1">MPDYQPSSGMATRRVQPRNSDEEANRSRTIRPDLEPAPQPWPGLPYVAVLVMCGFLALQLYPSTHWRHPQDRLKRWVPHGDPQIVQATGKDSFYSTLDEVQVQQAEDLAAQEELSALPKDEDHDEDTLAFLKKAGEQEVHIFVSTDASDFRPLAVLVNSTISNALHPERLHFHLVMPPSHRFRAKHLSAFFRDVKIEIVSENIDLKEMESHISFRNNSKARPELQSVYNFVPFLLPRYFKDIDRFIYLDADVVVKGNIEELLQIDLEDRAAAAVEDCSQKLETYFDFDQLAKIQARPNKPAWVPSVPINSEACVFNRGVLVINTKQWIKEQVTEAILWWMDEFHDADSVLYKYGLSQPPFLLALYGKYKKLETLWNVRGLGRHEFSEHEREFLEKKYNHKPDRKPFISFEADSAKILHFNGKFKPWKRVRPVGASKDVISRCGAKGVECAKLWWEYLSPLADEILKHDDTM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN69</accession>
    <name>A0A8T0GN69_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dof-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G149500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045174">
        <property type="entry name" value="Dof"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003851">
        <property type="entry name" value="Znf_Dof"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089">
        <property type="entry name" value="CYCLIC DOF FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31089:SF22">
        <property type="entry name" value="CYCLIC DOF FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02701">
        <property type="entry name" value="Zn_ribbon_Dof"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01361">
        <property type="entry name" value="ZF_DOF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50884">
        <property type="entry name" value="ZF_DOF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Dof-type" evidence="9">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="112"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="337"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="18"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="384"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0560037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="403" mass="43736" checksum="A2F01273F18261F1" modified="2022-10-12" version="1">MHLPISHLSGFEEDASEELQAQLQGAQSGSQDDEGSHNSQSQGSGKEGSKEGGSGDGAGGGDGAVGGRPPKDLPCPRCQSMNTKFCYYNNYSVNQPRHFCRNCQRYWTVGGTLRNVPVGGGSRKKSSRSRARSDPYYRPNAPATGSEEGQDDDQRDPRHGQHPAMARPMHPDGAFGDAGFPDFPMHPSQISSFLQFALHGQATHGLGLQFPPFLDPPGFAMTPEEEAELQAFYEATTQSGMMTTAAAMMGSGLWVPELEPAHVALMQKAALWAEAQRIQSMARRAQAAAWADQERECKPVVSPPILQQRAPMEEAGQRQQAAASLHRRPGFWETALMHSRPSRRPAGSSQRSSPWDEAKPEGDNSQNNIVAEDGTYSQPGYDVESSSWAPSTALNSSNPEMFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRJ0</accession>
    <name>A0A8T0GRJ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G132400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRJ0"/>
    <dbReference type="OrthoDB" id="2014733at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874:SF4">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33874">
        <property type="entry name" value="RING FINGER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27605" checksum="12264FE3900C8C2C" modified="2022-10-12" version="1">MGVNDVSEAVVEVAWAALNTQQEAELKELLAVEVIENDKLRRSLKVYEKVIEDLELADAVAAARIEDSSSDSASTASCQEPRTPDMYDKLRDKLSSPEFLQQLASNEGEKPVDPSVMRGGDQEKGLWMFVSDDNVLPKEERDELGTNEGYVVITQQDIVDGVACFVARSISSLPQSKTMSPDELQQAIISAFSELQKTGKLRNLWSCAHLLYAATSWGSTALGLYKNPVIRRAAWMAVYTSSSIILRLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTZ5</accession>
    <name>A0A8T0GTZ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G097000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTZ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="64"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0561845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="356" mass="38615" checksum="B0FDA891E52BA455" modified="2022-10-12" version="1">MSSEVISITLKKHTWTALEHLFQFYCTRAMPQSASSGSASAPDLKRHLLVPTQKSTKGISARASPQTSSSFYSSSQKSGLNGGKAISNRKLSQGTKDATANARVSSPESSAEITGAKFESSNKPNEAKHITGNAEPSLLISQPRLKDLSSQADLNVVHTNLVETWFNVDDPVFDDFVNIKADIDPQKARSEKQNSLGNSLLIAAEATANLGSSLQDNINNSCVKELIEGAIGVKTTFQLDEKNEDGIAPGKAVVEGLNSKIVPDVTVCYEAIQNSLKYEDGSTLLEKLAVRGKALREIRQACANQLRRTNHGIHVFRGWRGMKFLLPSSYVVVLSILLIFVNFFNNSAPDVHLTPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU69</accession>
    <name>A0A8T0GU69_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G013700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035734597" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="64" mass="7512" checksum="BA05598E5D28E350" modified="2022-10-12" version="1">MFRSLIFNFQVSAKLVTALNWLVASLWQPCHRKSDLTADMVTFVDERMHVVQIHFQCWDSAVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUJ8</accession>
    <name>A0A8T0GUJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G129000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="2">
        <location>
            <begin position="40"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1047" mass="119939" checksum="C76ED2ADF1F215C9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUW9</accession>
    <name>A0A8T0GUW9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin--tyrosine ligase-like protein 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G007800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tubulin--tyrosine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUW9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF39">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="74"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0560722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="514" mass="59605" checksum="2D127DCF95D3C55C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWF5</accession>
    <name>A0A8T0GWF5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G082000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWF5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071007">
        <property type="term" value="C:U2-type catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036002">
        <property type="term" value="F:pre-mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017070">
        <property type="term" value="F:U6 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12224">
        <property type="entry name" value="RRM_RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000476">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000036">
        <property type="entry name" value="Zinc finger CCCH domain-containing protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039171">
        <property type="entry name" value="Cwc2/Slt11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048995">
        <property type="entry name" value="STL11/RBM22-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032297">
        <property type="entry name" value="Torus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14089:SF6">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR RBM22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21369">
        <property type="entry name" value="STL11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16131">
        <property type="entry name" value="Torus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="9">
        <location>
            <begin position="228"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="157"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="311"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="345"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="398"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="421"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="444"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0564091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="479" mass="53980" checksum="F8BBB46775D5088A" modified="2022-10-12" version="1">MAHRMLRDVEADGWERSDFPIICESCLGDNPYVRMTKANFDKECKICTRPFTVFRWRPGRDARYKKTEVCQTCSKLKNVCQVCLLDLEYGLPVQVRDTALNINTSESIPKSDVNREFFAEEQDRKAKAGLDYESSFGKARPNDTILKLQRTTPYYKRNRAHICSFYVRGECTRGAECPYRHEMPVTGELSQQNIKDRYYGVNDPVAAKLLRKAGEMPSLAAPEDMSIKTLYVGGLVDRVTEEDLKDQFYSYGEIESIRMVPQRACAFVTYTTREGAEKAADHLANKLVINGLRLKLMWGRPQVAKADLEAAAEKNEDGKSNPGGGILSHGGMLPRALISQQQQHPHQHPHPHPHPHPGHEQVSNYFNLPPPTLSTDRPFYPSMDPQRMGAVMKHDSSGAEQGEGSSSEQRPQPGQYGGQPMGPPPYGYAQHGPPPHFQHQHFRGPPPFPQGGPPPHSYQPYPPPQFQGGPPPQYFRPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZS2</accession>
    <name>A0A8T0GZS2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">SSD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_8G045400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the patched family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005319">
        <property type="term" value="F:lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008203">
        <property type="term" value="P:cholesterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015918">
        <property type="term" value="P:sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1640.10">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053958">
        <property type="entry name" value="HMGCR/SNAP/NPC1-like_SSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004765">
        <property type="entry name" value="NPC1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053956">
        <property type="entry name" value="NPC1_MLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032190">
        <property type="entry name" value="NPC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00917">
        <property type="entry name" value="2A060601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45727:SF2">
        <property type="entry name" value="NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22314">
        <property type="entry name" value="NPC1_MLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16414">
        <property type="entry name" value="NPC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12349">
        <property type="entry name" value="Sterol-sensing"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82866">
        <property type="entry name" value="Multidrug efflux transporter AcrB transmembrane domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0153">Cholesterol metabolism</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 16" id="KW-0732">Signal</keyword>
    <keyword evidence="14" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="12" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035886919" description="SSD domain-containing protein" evidence="16">
        <location>
            <begin position="21"/>
            <end position="1264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="616"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="658"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="683"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="727"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="759"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1109"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1138"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1171"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="1204"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="17">
        <location>
            <begin position="617"/>
            <end position="781"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0563614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1264" mass="138904" checksum="AE61AFC95BCFD152" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H458</accession>
    <name>A0A8T0H458_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G081900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H458"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="93" mass="10230" checksum="D710F9768C4827A7" modified="2022-10-12" version="1" fragment="single">MIRSFVTSPRSLHSGFHFVAVAALRFASNGSLRLKFGSRGAITVEAQEARRHANIAVRFVGVWSGVLISRSSFRRIDDALLSEERVLVSTVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4X2</accession>
    <name>A0A8T0H4X2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 18">Pyruvate kinase</fullName>
            <ecNumber evidence="7 18">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_7G012700</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17 18">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 18">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 18">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="7 18"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4X2"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.60:FF:000001">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1380.20:FF:000005">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004491">
        <property type="entry name" value="PRK05826.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004978">
        <property type="entry name" value="PRK06354.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15 18" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="12 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="14 18" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 18" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="19">
        <location>
            <begin position="23"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="20">
        <location>
            <begin position="383"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0565757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="528" mass="57748" checksum="E8E613E0283397C6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H584</accession>
    <name>A0A8T0H584_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G199100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H584"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12586" checksum="9B72E4A02D2F809A" modified="2022-10-12" version="1">MPWSPHCILLSGTRWCTVQYSTVQGCFTYQKRMSGLQAGHGLLQTRGSRREQGMSMGFFWFDLPVCTLPNSISTSCKCGIFAIRFDLFNLVKSLRVKHGRWRMREIMIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5J1</accession>
    <name>A0A8T0H5J1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G105400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5J1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13848" checksum="BB59016772798568" modified="2022-10-12" version="1">MEHSTDRAMAAFTWPRLGTPVLREGAAMALLQAPWLAAIASEKVNKHRYCKRRVGCERRKEGSTRAGCKRINGNSSEHCTARQRQLRWQSRLKLERECERELGLLLECEDGNGVGCQQPRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5X3</accession>
    <name>A0A8T0H5X3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_7G043200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5X3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034732">
        <property type="entry name" value="EPHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050973">
        <property type="entry name" value="H3K9_Histone-Lys_N-MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007728">
        <property type="entry name" value="Pre-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223:SF3">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SET-23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46223">
        <property type="entry name" value="HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05033">
        <property type="entry name" value="Pre-SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13771">
        <property type="entry name" value="zf-HC5HC2H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51805">
        <property type="entry name" value="EPHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="12">
        <location>
            <begin position="287"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="10">
        <location>
            <begin position="624"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="11">
        <location>
            <begin position="767"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="416"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0566165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="785" mass="88047" checksum="8BEBB3D21E95BBEF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H652</accession>
    <name>A0A8T0H652_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Serine incorporator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G088800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TDE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H652"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005016">
        <property type="entry name" value="TDE1/TMS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383">
        <property type="entry name" value="SERINE INCORPORATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10383:SF9">
        <property type="entry name" value="SERINE INCORPORATOR, ISOFORM F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03348">
        <property type="entry name" value="Serinc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274495" description="Serine incorporator" evidence="8">
        <location>
            <begin position="18"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="305"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="331"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="431" mass="47290" checksum="D35A2DFC32BDCCEA" modified="2022-10-12" version="1">MWAAGCLASCCASCACAACQGVASGISRRSARIAYCGLFAMSLIVSWLLRDFAGPLLAKIPWINTFTDTPSPEWFATQAVLRVSLGNFLFFVAFAVLMIGVKDQREQRDAWHHGGWMVKLILWCITIILMFFLPNGLVNAYGSVSRFGSGLFLLIQVVILLDFTHNWNAAWVAKDEQFWYIALLCVSVGCYLASFVFSGFLFHWFTPSGEECELNTFVIAFTLILGVSFAIVSLHPQVNGSLLPAGVIAAYCTYLCYSALSSEPRDYECNGLHKHVNAVSKGTLGLGMLTTLLSVVYSAVRAGSSTTFLSPPSSPTAGGSKKALLSNNDVEGGDESESDDDTKPIRRGGRHSKEPRPVTYVYSFFHLIFALASMYSAMLLTGWGNANMAEKDIIDVGWPSVWVRIITQWITAALYVWSLVAPQLFPDRDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H826</accession>
    <name>A0A8T0H826_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA-directed RNA polymerase subunit</fullName>
            <ecNumber evidence="6">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G059400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>RNA(n) + a ribonucleoside 5'-triphosphate = RNA(n+1) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.180">
        <property type="entry name" value="RNA polymerase ii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="entry name" value="RNA polymerase II, clamp domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="entry name" value="RNA polymerase Rpb1, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376:SF36">
        <property type="entry name" value="DNA-DIRECTED RNA POLYMERASE IV SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11523">
        <property type="entry name" value="DUF3223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64484">
        <property type="entry name" value="beta and beta-prime subunits of DNA dependent RNA-polymerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA polymerase N-terminal" evidence="8">
        <location>
            <begin position="291"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1462"/>
            <end position="1505"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1545"/>
            <end position="1579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1820"/>
            <end position="1850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="1462"/>
            <end position="1479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1558"/>
            <end position="1579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1876" mass="209646" checksum="1AD5982E81A7781A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HA68</accession>
    <name>A0A8T0HA68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">glutathione transferase</fullName>
            <ecNumber evidence="2">2.5.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_7G108000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>RX + glutathione = an S-substituted glutathione + a halide anion + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16437"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16042"/>
            <dbReference type="ChEBI" id="CHEBI:17792"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:90779"/>
            <dbReference type="EC" id="2.5.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GST superfamily. Phi family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.18" evidence="2"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HA68"/>
    <dbReference type="OrthoDB" id="422574at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043295">
        <property type="term" value="F:glutathione binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009636">
        <property type="term" value="P:response to toxic substance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03187">
        <property type="entry name" value="GST_C_Phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03053">
        <property type="entry name" value="GST_N_Phi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000004">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000016">
        <property type="entry name" value="Glutathione S-transferase F2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034347">
        <property type="entry name" value="GST_Phi_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43900:SF3">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00043">
        <property type="entry name" value="GST_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02798">
        <property type="entry name" value="GST_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01154">
        <property type="entry name" value="Main.5:_Phi-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00358">
        <property type="entry name" value="Main_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="5">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="GST C-terminal" evidence="6">
        <location>
            <begin position="90"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0567069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="215" mass="23810" checksum="9F63A1CA0D141FCF" modified="2022-10-12" version="1">MTLIVHGAPYSTCTQRVLTTLAELNVEDYKLELVDLSKGAHKGPDFVKLQPFGQIPVLQDGDITIFESRAIVRYLCEKFAGHGTPLLGKTVKDKALVSQWLEVESQNYNPATATIVFEKVFGPMFGKPCDDAVVAAQTAKLEKTLDVYEAHLAKSKFLAGDFFSLADLSHLPYTNMLVYAAGKSDLITSRPHVSAWWNAISQRPTFQKVLALQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAV4</accession>
    <name>A0A8T0HAV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G028200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050258">
        <property type="entry name" value="Leguminous_Lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32401">
        <property type="entry name" value="CONCANAVALIN A-LIKE LECTIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32401:SF48">
        <property type="entry name" value="LEGUME LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="352"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="510" mass="57391" checksum="155E533641DC2ED3" modified="2022-10-12" version="1" fragment="single">MSRAMASCYHFALAELLLVGQIILGAVIVQAQTNFSFLSFPTAESFLVLNDTVHVGNSSFLLNVQGARMSPSCGRLLYNEKIKMKDMASGAVASFHTAFTFQIYGPNMIFVAPEVYYHGDGLAFTFVRSITLSDAVESGSELCLLDRAIDGSINPLFAIEFDTYKTHWFGDISDSHVGVNIDSMRSIWSYNLCESSENQEYCSYLANGGYFTAWIDYYKTSEILQVFLASGSLDDISKPLKPLIEANISKFMPLANLVDEFMYVGFSSGTGVHWEVHEIKSWTFTSSMTQQETVVLSGDQSSGSPVKQIIIGVSVAGGILLLASWKVLGGPLKTPTYSQTSFELQPLTQGLETFRIFISHTGGPNGSEKNFPINLSKALKDYAEEKKCNYEVFIDRKMEKGTKFPEEILRQIAMTHLGIVVVTKEFFKNKWPMIELAKFVELYKPPEVLILPLFYKLKPAEVRSHLEKKFWERFWTEMSSPNHPIDLEKYRNAVETLCNINGVEYNFWND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HB77</accession>
    <name>A0A8T0HB77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G026100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HB77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5948" checksum="2288AB11DBED5909" modified="2022-10-12" version="1">MSNDFIYLWFWFKIPSIDRSICMQCVCISKCSIHHALIIYTFHVRPRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBI9</accession>
    <name>A0A8T0HBI9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G035200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBI9"/>
    <dbReference type="OrthoDB" id="2020323at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37727">
        <property type="entry name" value="ECOTROPIC VIRAL INTEGRATION SITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37727:SF1">
        <property type="entry name" value="ECOTROPIC VIRAL INTEGRATION SITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="13670" checksum="A6A2AFBF60BE7BC4" modified="2022-10-12" version="1">MGGVKKPQAQLLDDQLFQFLHGLLDQVEASSGVEETELKAKIAALQSETRKTPAASTSHMSEVDVARELDNMSAKLESLGALVDEVASDPEVQGLLASSANLWVPVITASAEERTAKAPVEDTPDSSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBL5</accession>
    <name>A0A8T0HBL5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G069800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBL5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035906098" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="9456" checksum="0C6035CCDC1C9743" modified="2022-10-12" version="1">MNWYWKWHIGRFELVVTWLDSVVLYQNKGKRSTTACARFPSLTSQVILEGCYFVTDGRLSTPQVIQHRGGKTLRRLSLPEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD18</accession>
    <name>A0A8T0HD18_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SBP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G109800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD18"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1100.10:FF:000001">
        <property type="entry name" value="Squamosa promoter-binding-like protein 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1100.10">
        <property type="entry name" value="Transcription factor, SBP-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044817">
        <property type="entry name" value="SBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004333">
        <property type="entry name" value="SBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036893">
        <property type="entry name" value="SBP_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251:SF86">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26102">
        <property type="entry name" value="Ig_SPL7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03110">
        <property type="entry name" value="SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103612">
        <property type="entry name" value="SBT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51141">
        <property type="entry name" value="ZF_SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1228"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="domain" description="SBP-type" evidence="10">
        <location>
            <begin position="211"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="91"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="513"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="789"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="122"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="204"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="276"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="518"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="588"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="824"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="847"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0569706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1270" mass="138415" checksum="EB2CA6280972E69B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDF2</accession>
    <name>A0A8T0HDF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH kinase</fullName>
            <ecNumber evidence="11">2.7.1.86</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G082300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.86" evidence="11"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDF2"/>
    <dbReference type="OrthoDB" id="185618at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042736">
        <property type="term" value="F:NADH kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP+ biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.200.30:FF:000015">
        <property type="entry name" value="NAD(H) kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10330:FF:000027">
        <property type="entry name" value="NADH kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275">
        <property type="entry name" value="NAD KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20275:SF28">
        <property type="entry name" value="NADH KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="322" mass="36093" checksum="BF8F2079E5A4FD5B" modified="2022-10-12" version="1">MAAMAARMRRVLVLAKRSAYDMYVARHQDPAFTRFLSEPQMVGNLRDRHEVHERTVRVCKDILSRRQPHVQFEMHLRDELQSPIRDVDLVITVGGDGTLLQASHYVDNSIPVLGVNSDPTQTDEVELNLHRFDASRSTGHLCAATANNLEQMLDDILDGGMKPVELTRISTFIDGVKIDAPALNDVLIAHPNPAAISRCSFSIRREDVEESCTPIIHSRSSGLRISTATGSTAAMKSAGGTVMPVLSTNLQYMVREPNSPHPNYTRFMQGFLESKRILKIDWRSRKGVVYVDGSHLCYPIDFGCKIDVSNDAPPLRIFWKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDH2</accession>
    <name>A0A8T0HDH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_6G056300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDH2"/>
    <dbReference type="OrthoDB" id="421226at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.630:FF:000003">
        <property type="entry name" value="Cyclic nucleotide-gated ion channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000024">
        <property type="entry name" value="Cyclic nucleotide-gated ion channel 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45651:SF12">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45651">
        <property type="entry name" value="CYCLIC NUCLEOTIDE-GATED ION CHANNEL 15-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1071">Ligand-gated ion channel</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="377"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="405"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="12">
        <location>
            <begin position="509"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0568975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="733" mass="84101" checksum="E9A570D6EB3C625D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE27</accession>
    <name>A0A8T0HE27_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G135800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE27"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371:SF6">
        <property type="entry name" value="MEMBRANE-ASSOCIATED KINASE REGULATOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34371">
        <property type="entry name" value="OS01G0551000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="515"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="697"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="735"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="780"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="864"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="962"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="387"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="587"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="623"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="711"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="735"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="809"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="828"/>
            <end position="846"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1151" mass="126268" checksum="F7FE7166BBD0CCEF" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HES6</accession>
    <name>A0A8T0HES6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine/threonine-protein phosphatase 2A activator</fullName>
            <ecNumber evidence="7">5.2.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphotyrosyl phosphatase activator</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G069400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PTPA-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="7"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HES6"/>
    <dbReference type="OrthoDB" id="16120at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008160">
        <property type="term" value="F:protein tyrosine phosphatase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007052">
        <property type="term" value="P:mitotic spindle organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04087">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1150:FF:000002">
        <property type="entry name" value="Serine/threonine-protein phosphatase 2A activator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004327">
        <property type="entry name" value="Phstyr_phstse_ac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043170">
        <property type="entry name" value="PTPA_C_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037218">
        <property type="entry name" value="PTPA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10012:SF0">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03095">
        <property type="entry name" value="PTPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140984">
        <property type="entry name" value="PTPA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0569157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="408" mass="45218" checksum="D8F5A43930DAC505" modified="2022-10-12" version="1">MAEGESTSRALEEQTLGAAEKSVEPVGADRAVSESQGRNGSGSGLGASGGGLQWPAPSSSPQMGRMQAPMSMPMPVSYPEMGSSPASAPQMSMAALAPVPQARPVPVVQPPIAFQVPRKRINSVADIEHFHKSEAGKTFLGFVVGLSDSMVGKKLSDYCRESPIIKTLCGMLEEMSSWIEQLPPKQQPARYGNPAFREWQTWLEERGPGLMLRVLPENLKDGVDEIFPYFADSFGNATRIDYGTGHEANFAAWLLCLARLGLLNEDDYQALVARVFVKYLDLMRKLQTTYWLEPAGSHGVWGLDDYHFLPFIFGSAQLKDHKYMKPKSIHNQDILDTFSHEYLYLGCVQFVKRVKKGALAEHSPMLDDISAVLSWNKVNSGMLKMYKAEVLEKVPIMQHFLFGSLIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF30</accession>
    <name>A0A8T0HF30_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G064000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF30"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31389:SF9">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31389">
        <property type="entry name" value="LD39211P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="606" mass="66734" checksum="768679F6F7B131F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGI1</accession>
    <name>A0A8T0HGI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G102400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="40" mass="4624" checksum="19BD4DF82395AB83" modified="2022-10-12" version="1">MRMIHWEVTQITGDDLRHSDNSIKEGSLIPAILINQMRCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGS1</accession>
    <name>A0A8T0HGS1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G122000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="17"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1142" mass="129961" checksum="99600F1B50ED993A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HH71</accession>
    <name>A0A8T0HH71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G186500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HH71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="151" mass="16861" checksum="34682F7F212B5119" modified="2022-10-12" version="1">MAPFTCYTQTRRGITWLLRQSRKINANVELSTTPVCHSRSSATKEAGFTVCSAFTVGFDKPINISDEGLMPQAMNRVRRTECSKSPQEHGARFQIFNLRGLACCSYGICWLVSWGLSGVMLLCTELELLLPVLWFGSCPCSRLLRSISDET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJP8</accession>
    <name>A0A8T0HJP8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G205200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJP8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="372" mass="42240" checksum="35E38118DF9E3990" modified="2022-10-12" version="1">MDCALDESDARDLGHLGAFVNVSEHNSVPCFYSCTISIASYSQPAFYVLVSRRANDWGAHEDYFVKAVNLVEAIRILVACPTLTEVQFSFGGMAHWEVWNSVLPWSENLLSEVFTLLRSSPSLSCFHFINSQTVHYANLYCKHLQALVCENPRLETLTVSAHGPILVVAKAIADCLSRNTVLKSFTLRIPTLSNDQKQQSLEILLRPFTSSSPSEANASLKELALHLQYADGYCGDAIANLVCRNTTLKKLDLFFPRNFYSWRELRALASALQSNTTLKHVQCINGLDGYGNYTRDDAKKVTDKNLWQEEFQIQEILRTMIDNELRINTRLESFVVGHWTLLRVGTEWRTSYRGPCLREQIKEYNVKVKMIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLC9</accession>
    <name>A0A8T0HLC9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG028500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLC9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19471" checksum="39E7D1800642FBB0" modified="2022-10-12" version="1">MLFLHFHVGLWSKMPLGELKPLLTHILPAGVIERLSFVYSRSDLIERENFPWSYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRRTPNCMCYIPWPFQGHLNFPNDDGVIPNIATDILPLVYPLHMFGSVPEYMAQACRPRQGHWAIEAARKFGRARVDWTEVCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLE1</accession>
    <name>A0A8T0HLE1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG029500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009451">
        <property type="term" value="P:RNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046960">
        <property type="entry name" value="PPR_At4g14850-like_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47926">
        <property type="entry name" value="PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01535">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="92"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0571636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="150" mass="16764" checksum="CD26F7F262F0D47F" modified="2022-10-12" version="1">MVNLRLGAAQNGYFDEAFKFFEAMRNEGRKPDKLTSICILNACSSLEQGRILHSDIVKASFELDVRVGTALVYMFSKCGSVEDVLQVFEKLPQRNVVSMIAANAQNSKFEKALEYFEKMLKEGILPDKRAYTIVLNVCTSGRLGERGTSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLQ4</accession>
    <name>A0A8T0HLQ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG036000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLQ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8366" checksum="79576267367409AF" modified="2022-10-12" version="1">MYTLSRSIRASLLRRNLHIKLMIYVKLPRGMAASVPKVHFVAEQNCKESRSIHHLPHSIGAFYYPRPVPFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLR0</accession>
    <name>A0A8T0HLR0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG040000</name>
        <name evidence="7" type="ORF">KC19_VG042000</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.395.10">
        <property type="entry name" value="Adenoviral Proteinase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="5">
        <location>
            <begin position="1"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="219"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0571759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="243" mass="27712" checksum="9F11DE6B8525317F" modified="2022-10-12" version="1">MDFFCAWFQDCVPEPILLCNSLPATALYEVIRKTTDIEALRRCFHMSSEFRHVKGNTIMVPIVNSEHWSLAILSGEHFLKFDSNSGETLHGSTKLHQSLGKLWCMAVGHEEGSATWVNATDLNSWIRVKCPQQGDDWSCGYYVMCYIIMYVTYWSNKRFVDWRQEISHIFGEKEVLEIKAELKTAILRAIVTGLVDDSECKVSVGFHDVIASKVQDRTKVKTRDASPPRRSGRIKEKTGATWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLV2</accession>
    <name>A0A8T0HLV2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG043400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15900" checksum="5557848903DF4812" modified="2022-10-12" version="1">MAVDKGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSGARKSGDSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVDGMSWTCQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRP0</accession>
    <name>A0A8T0HRP0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG179900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8289" checksum="B6DB6E2EBE59302C" modified="2022-10-12" version="1">MAQESSLVHNFLSHALILLVLVIGGRCMRSMSQMTAGFTRKSAVFVRLDYVTVNAKLFSPYSAVTLSCPPKRGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HS34</accession>
    <name>A0A8T0HS34_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG188000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HS34"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035802055" evidence="2">
        <location>
            <begin position="24"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="177"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="20407" checksum="078D047440F8A977" modified="2022-10-12" version="1">MAFSTSPMSLVRYFLILQSVVLQMGEITVCSRFYTQQERNDLVFPELPVLSSLLLQTGEFQLSNACYEEIFALGTAAGVPFLTYLQNREASYLELRPGNTVANPIVIHSVSEDSPPAGGAPSSVSAHAGSFSGAEVDVVKVSSGNDGEEQGAGDEVEQGAGDGEDEGHGDDDDQEKDDVKEQGADDGEDHGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HU61</accession>
    <name>A0A8T0HU61_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG266600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HU61"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8321" checksum="F6EC651B4B7FD1D5" modified="2022-10-12" version="1" fragment="single">LAIRKGNLDDSTNSGSKLIQESFSQSLNLGNQSLNLGKFDRFAGRVILLFLFFFFRFRRLHCLCSTPLFSKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUI3</accession>
    <name>A0A8T0HUI3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG263500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="28311" checksum="C855890763E66FD7" modified="2022-10-12" version="1">MLSKQSQVGLFGTRRRGESRGGEGGGEERKHKGRGVPSTPPHTAVPGDGHGRPRVDGRRPRPSDLLRREDPTAADDGRPRGDGRGRPRVDGLGRLRGRSPPTPGSAAAVPAGSDKAVPAWTAVADPAVGRSVRVDGPRRPRGRPWPTAGWSTAVPAGSDKAVPGDGHGPPRGRKGRRRGRPWPTTPLQPPTAGWSTAVPAVGRGRPQGRPSTWSAVPTAGRRSTDAPFGERSRPHDRSRPRSWTAATAPATDQLRPLDSPFPEIQRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUQ5</accession>
    <name>A0A8T0HUQ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG273100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUQ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47513:SF1">
        <property type="entry name" value="OS07G0283200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47513">
        <property type="entry name" value="ZINC TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="359" mass="38874" checksum="D43E103C25AC3E4C" modified="2022-10-12" version="1">MLPPRLNVEAFALPPAATKMAPMHAIHIVGRCLRLVSVYAAYHYVIARGVSLTLFVFVCLSGSAAVFSALQRPWRGRPLPNSLLGPALVNGGVMAFSLLLWANGLRNCGPVRTILGEYAGAVLGALSTLLFSRNGLVWRRIGGLLAMCAAYYLLSQGWAMSSYSPFSFGSTNVKEVLVEEEEGLIKSSSMLLPAFSGILAAIRRIISRRVSMKNHAKKRLHAVTVAAAACFIFPFAMFKLAVGKQHSSSEPYGSAAWAYTSTILFGVVLIFYVDTFVEDRLHIVVASPTHILVTGVGIVLFEYIYGMDFSLLGFVICATILGLGIYEATATEPNIRDLDQGNSFLKEDRSSVNVLTLPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUX3</accession>
    <name>A0A8T0HUX3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG291900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035818308" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7618" checksum="72D3CD5B3208883D" modified="2022-10-12" version="1">MWVLQFLGWWRVLCLWKSFGRVLEEFGKVFVGVWEGSGHGDWSSDVRTWVQWTNSRLGFGFEAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HV31</accession>
    <name>A0A8T0HV31_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG303300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HV31"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039218">
        <property type="entry name" value="REM_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM-LIKE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674:SF62">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM14-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="18"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="204"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0574932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="239" mass="27050" checksum="37F7F16E7851A56A" modified="2022-10-12" version="1">MDEQDEQEVAEIEDVRQFYFTVNMLTRSRRTHLEIPEAFTDKTGWPTCEECALVTSSSDRRDWPVHFRFEDVGGGKRTARSVGHGWTVFLRDQNVKSGSLLILEVMDSRSLAVTICHPDSPRKHVVKTQEAALRRRSDGPVFTKTVRASHLRPGLAARLDLPTSYWREVGAERFRDTWFTLVGPLSAVRVKSAAYVTPTQTFCYLSRGWSDFVALNDFKLGDTLQFAAVGTAEFNVSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX76</accession>
    <name>A0A8T0HX76_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G006500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX76"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16263">
        <property type="entry name" value="BipA_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03691">
        <property type="entry name" value="BipA_TypA_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01891">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000016">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.250:FF:000001">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000002">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000003">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000055">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="BipA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047041">
        <property type="entry name" value="BipA_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047042">
        <property type="entry name" value="BipA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047043">
        <property type="entry name" value="BipA_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="1">
        <location>
            <begin position="92"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="685" mass="75314" checksum="1BDC85AF89E54987" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXD1</accession>
    <name>A0A8T0HXD1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Autophagy-related protein 14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G028300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXD1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035493">
        <property type="term" value="P:SNARE complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018791">
        <property type="entry name" value="UV_resistance/autophagy_Atg14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15157:SF5">
        <property type="entry name" value="UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10186">
        <property type="entry name" value="ATG14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="409"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="446"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="85"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="463"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0575754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="522" mass="58349" checksum="ECDB79EEB9791CC8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZS6</accession>
    <name>A0A8T0HZS6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G032500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16109" checksum="DDB62BEED55F044A" modified="2022-10-12" version="1">MVVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1N1</accession>
    <name>A0A8T0I1N1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta-fructofuranosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G149900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1N1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18624">
        <property type="entry name" value="GH32_Fruct1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.115.10.20:FF:000001">
        <property type="entry name" value="Beta-fructofuranosidase, insoluble isoenzyme CWINV1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.560">
        <property type="entry name" value="Exo-inulinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="entry name" value="Glycosyl hydrolase domain, family 43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050551">
        <property type="entry name" value="Fructan_Metab_Enzymes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001362">
        <property type="entry name" value="Glyco_hydro_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018053">
        <property type="entry name" value="Glyco_hydro_32_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013189">
        <property type="entry name" value="Glyco_hydro_32_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013148">
        <property type="entry name" value="Glyco_hydro_32_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31953">
        <property type="entry name" value="BETA-FRUCTOFURANOSIDASE, INSOLUBLE ISOENZYME CWINV1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08244">
        <property type="entry name" value="Glyco_hydro_32C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00251">
        <property type="entry name" value="Glyco_hydro_32N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00640">
        <property type="entry name" value="Glyco_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="Arabinanase/levansucrase/invertase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00609">
        <property type="entry name" value="GLYCOSYL_HYDROL_F32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyl hydrolase family 32 N-terminal" evidence="5">
        <location>
            <begin position="83"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 32 C-terminal" evidence="6">
        <location>
            <begin position="407"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="618" mass="68947" checksum="5F6AD2E7E160E42A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I2A8</accession>
    <name>A0A8T0I2A8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G128100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I2A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13167" checksum="7B1B9E6A03C3960C" modified="2022-10-12" version="1">MSTVQRGHPNAELEDGINCHPKFWKVVITRVKIFTIFLFNEVLKSTPKNNLSSKKNCKNHFTMSCDLIQEFDGHLSLMQRSNDGCPGNIFGPRVQVAVAVHALSLIFLSNYDPTLCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3I8</accession>
    <name>A0A8T0I3I8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G161400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3I8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="193" mass="20647" checksum="E687D20A7AE9BEA0" modified="2022-10-12" version="1">MSSTTQHSTHHPADPPLLPLARKKRDQKATASIDDADHQQPPCPSYLNLNVPNGHPCALSLSLSPKLPGPGSLSLSLSQSVTPVPPPEICLPRPPPKAMTLAVLDNVGVTGATEFPPNATDSARHQSIAACLLANFTLLASKDASNTRSDGDAHAALPARRPVSMCCRCCMLVICRFLFLASRFWLLTSRVWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7D2</accession>
    <name>A0A8T0I7D2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G097800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7D2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="82" mass="8997" checksum="2129D8D80B3E0E68" modified="2022-10-12" version="1">MDSRLHVTEADAFEVQRVLKIAVMCAQVSPDKRSTMFRVVAMLAGDANVVVAPIDDSDVGPMFDFTHYQSAPENSFYCSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7H2</accession>
    <name>A0A8T0I7H2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G018100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7H2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5535" checksum="FB72B6F84630C4FB" modified="2022-10-12" version="1">MKFGGIVQVREELCEIWFHLGVAVIQLLCLTSLEVSCSMQSDYVKSDPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I955</accession>
    <name>A0A8T0I955_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">C2HC/C3H-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G104800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I955"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026319">
        <property type="entry name" value="ZC2HC1A/B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049899">
        <property type="entry name" value="Znf_C2HC_C3H"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555">
        <property type="entry name" value="C2H2 ZINC FINGER CGI-62-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13555:SF68">
        <property type="entry name" value="ZINC FINGER PROTEIN 474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13913">
        <property type="entry name" value="zf-C2HC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52027">
        <property type="entry name" value="ZF_C2HC_C3H"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C2HC/C3H-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="C2HC/C3H-type" evidence="7">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="29"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS52027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="14915" checksum="C8125967F9D496CA" modified="2022-10-12" version="1">MLVCYLCSREFGSKSLPIHIPQCQKKWLQEEEQKPKKDRRPLPLPPAAEQPITTGGGAPSAQAIDDFNDEARAAFEASLEQCPNCQRRFVPKALTHHSKACTSKNPAKPAGTGLTPMSLTNRLVPGAIAGSQHGKASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9X4</accession>
    <name>A0A8T0I9X4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G106900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9X4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035934778" evidence="1">
        <location>
            <begin position="20"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5698" checksum="8DB3A55E31E7DD0B" modified="2022-10-12" version="1">MRILYSSASFLHLLLQAEPVVTCNYGRCQYLKGGKAAGLGSLSLQNNMKLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA96</accession>
    <name>A0A8T0IA96_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G126500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA96"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044800">
        <property type="entry name" value="LEC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31140:SF81">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR ABI3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="520"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="236"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="315"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="452"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="618"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="237"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="323"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="453"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="633"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="651" mass="71486" checksum="D016FE397372992A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAK2</accession>
    <name>A0A8T0IAK2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Disease resistance R13L4/SHOC-2-like LRR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G136100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAK2"/>
    <dbReference type="OrthoDB" id="1668230at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050216">
        <property type="entry name" value="LRR_domain-containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48051:SF56">
        <property type="entry name" value="PLANT INTRACELLULAR RAS-GROUP-RELATED LRR PROTEIN 6-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Disease resistance R13L4/SHOC-2-like LRR" evidence="5">
        <location>
            <begin position="283"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="468"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="115"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF23598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="494" mass="54275" checksum="B22A27D17000088E" modified="2022-10-12" version="1">MSFEEVEMGGGGEEIQVKVLSDVTEFNPLALAVVKLSDARAKVKELGPRPDPVDVEEARKAILRIQDALQDQVGEVYAAPCPPGHDLERWQSSQTEKVKALEESAAKAREPYEALLELEELHILYEEEVKQAELAVEGMEEEPSASNVEAEEEVDEYVSSKLQEALENQLDTLDLSSQFLSYVPESFGRISSLVILNLSNNRLEFLPDSIAGLVNLEVLDLQHNQLKLLPDSIGLLSKLKSLDVSGNALRVLPASLGRCSALVEFIANFNQLEVWPSDFGFQLNNLQTLSLHLNKISSLPPSIGELRALRFLDVHFNKLRGLPSTIGNLSNLTVLDVSSNFRDFAALPDSVGDLVSLTEMDLSFNQIHELPISMGRLTNLRKLKLEENPLMVPPMEVVEQGHEALMQYMAKLWSESLKTEEEKNLAKSSSFGRAFQGNGSTEGWIPAWAGGSLVNSWLGKVQAGGLGSLLGGGKPSSPRAKTQSTDDSYLDQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAS5</accession>
    <name>A0A8T0IAS5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Uridine 5'-monophosphate synthase</fullName>
            <ecNumber evidence="5">2.4.2.10</ecNumber>
            <ecNumber evidence="6">4.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_4G133000</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>orotidine 5'-phosphate + H(+) = UMP + CO2</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the OMP decarboxylase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="5"/>
    <dbReference type="EC" id="4.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04725">
        <property type="entry name" value="OMP_decarboxylase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000092">
        <property type="entry name" value="Uridine monophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2020:FF:000025">
        <property type="entry name" value="Uridine monophosphate synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014732">
        <property type="entry name" value="OMPdecase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018089">
        <property type="entry name" value="OMPdecase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010382">
        <property type="entry name" value="PRK13809.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01740">
        <property type="entry name" value="pyrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278">
        <property type="entry name" value="OROTATE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19278:SF9">
        <property type="entry name" value="URIDINE 5'-MONOPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00156">
        <property type="entry name" value="OMPDECASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Orotidine 5'-phosphate decarboxylase" evidence="18">
        <location>
            <begin position="246"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="active site" description="For OMPdecase activity" evidence="16">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00049157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR614732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0579901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="476" mass="50876" checksum="70A9CFB7B1F54F76" modified="2022-10-12" version="1">MEDAAVESLVLALHGVEAVKFGEFKLKSGITSPIYIDLRVIVSYPALLQQVSEAVWATVAGVEQDVICGVPYTALPIATAISLKHDVAMVMRRKEVKDYGTKKAIEGFFRVGDKCLIIEDLVTSGASVLETVEPLVAAGLKVTDVVVLIDREQGGPQTLAKHGLRLHAALKLTRIVEVLVRHGKLTREVADSVEKFLSENQTTVSVPPVAQTPAKLRRVPFGERAGLSKNPTGKRLFELMERKQSNLSVAADVNTASELLALADAVGPDICVLKTHVDILPDFTPDFGSKLREIADKHDFLIFEDRKFADIGNTVTMQYEGGIYKIVDWADITNAHVVPGAGIVDGLKLKGLPKGRGLLLLAEMSSKGTLAKGEYTEAAAKIAADHPDFVIGFISTNPAAWVGGPGSPALIHMTPGVQMSAGGDSLGQQYNTPSSVIGERGSDIIIVGRGIIKAADPAAAAKEYRKAGWTAYEQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAU4</accession>
    <name>A0A8T0IAU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G145200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAU4"/>
    <dbReference type="OrthoDB" id="1911461at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36070:SF1">
        <property type="entry name" value="OS04G0165500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36070">
        <property type="entry name" value="OSJNBA0019G23.7 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="69" mass="7131" checksum="E47B15675081C6A3" modified="2022-10-12" version="1">MVSRNAILASGLVAFATAGLLFPLVLSKSQSKPIIDSSKPLSPGAIMRGPYINAGSRDVGPDPAPRKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IEK4</accession>
    <name>A0A8T0IEK4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G040600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IEK4"/>
    <dbReference type="OrthoDB" id="755532at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33237">
        <property type="entry name" value="F2P16.13 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33237:SF21">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="15"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12546" checksum="77559E14987AAE9F" modified="2022-10-12" version="1">MGMCAMYSFKYGRRPMLPLEDGEDHDSPRSGTSSSDGSAILGTKGWRETKRGANQYDQHPALWKRTIPKGRRCEPLDFSGLILYDEHGNRLHHFTPNPYPRDRPDQVDVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIC0</accession>
    <name>A0A8T0IIC0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G146300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIC0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="49" mass="5416" checksum="4908B50DB7A760A2" modified="2022-10-12" version="1">MLCLSSVATAVTALAPGNFYCTPQRACPTNFTEFPCEFLERTNSDRVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIJ7</accession>
    <name>A0A8T0IIJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G089000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="11837" checksum="397A8B679E861B48" modified="2022-10-12" version="1">MKLSVAISISPLAIAISKDSPALLTLRAHTRIPPHPRQALLLPAHRTACAGPETVACGCWNTHLKSLSDAGIILHSVFADVRVSDRASSFFPILVNSVPFRPRRRKPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJA0</accession>
    <name>A0A8T0IJA0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Mitochondrial import inner membrane translocase subunit tim23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G102000</name>
        <name evidence="6" type="ORF">KC19_3G102100</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJA0"/>
    <dbReference type="OrthoDB" id="159299at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005744">
        <property type="term" value="C:TIM23 mitochondrial import inner membrane translocase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030150">
        <property type="term" value="P:protein import into mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045238">
        <property type="entry name" value="Tim23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371:SF0">
        <property type="entry name" value="SD19278P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15371">
        <property type="entry name" value="TIM23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02466">
        <property type="entry name" value="Tim17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0583009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0583010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="198" mass="20592" checksum="FB9C50A5DE18B46F" modified="2022-10-12" version="1">MSDERGASEGGGVFGEEAGQGTGRLYNPYADLYGAADLKSLESVYRLPSAPEYLFPDEAAVQRRNWSENLTYYTGCGYGVGALAGGAKGAVEGLRSQEASDTLKIRVNRLLNASGHRGRVMGNTLGILGLLYAGFESTASHYRDTDDMLNTVIAGLGTGVVYKAAAGPRTAAIAGALGGFAAAALVAGKQVSKRYMPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK86</accession>
    <name>A0A8T0IK86_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G192000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1000.10:FF:000001">
        <property type="entry name" value="zinc finger CCCH domain-containing protein 15-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24203:SF86">
        <property type="entry name" value="PROTEASOME 26S SUBUNIT, NON-ATPASE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="394"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="469"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="611"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="11">
        <location>
            <begin position="669"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="742"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="611"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="669"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="838"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="895"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1038"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="838"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="900"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="937"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="952"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1039"/>
            <end position="1049"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0584190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1080" mass="116843" checksum="A186475AB4BC95FC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKI3</accession>
    <name>A0A8T0IKI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">protein-histidine N-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.85</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_3G144800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methyltransferase superfamily. METTL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.85" evidence="3"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018064">
        <property type="term" value="F:protein-L-histidine N-tele-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF39">
        <property type="entry name" value="HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="424"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00038126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0583535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="451" mass="49728" checksum="D38A56D342033249" modified="2022-10-12" version="1">MEENVVFRFNFAAAATPQQEQPQPQSLLKNSNALGIAAEQPLLPPPPPSEEVFPSEAEESTSCVMEPIALQGGMTLLKGRVNSQSILKVSNSDLVPGKYEGGLKLWECTIDLVETLRREIQDGQLSFRGKRVLELGCGHGLPGIFACLKGASSVHFQDFNAEVLRNLTIKNVQANLEQARGGLVRINSVSSDGIAANKGLVVAPDIHYYAGDWSDVHDVLSVVRCGSAGSGDNEDGAFNFRFNESDLYEPMPESGDNEIKSGGLSRTGSKNRLARKLSGSQACERGHTNTTQEGGYDIILMSETVYSLASLPKLYELIKKCIRPPYGVVYVAGKKHYFGVGGGTRQFKHLVEDDGTYLRLAFTIFHCMNVSFIWKVRAFRTGSSRVCFCSICIFFVNYVSLLIYSNSCSLLHESNWLYTLDQCWKVGSSANLCIHFVSFFLHYRVLVRSDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKN5</accession>
    <name>A0A8T0IKN5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA helicase</fullName>
            <ecNumber evidence="6">3.6.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Protein SUPPRESSOR OF VAR 3-like</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_3G204900</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer; in free form. Component of the mitochondrial degradosome (mtEXO) complex which is a heteropentamer containing 2 copies of SUPV3L1 and 3 copies of PNPT1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Mitochondrion matrix</location>
            <location evidence="4">Mitochondrion nucleoid</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="6"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKN5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045025">
        <property type="term" value="C:mitochondrial degradosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042645">
        <property type="term" value="C:mitochondrial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000965">
        <property type="term" value="P:mitochondrial RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17913">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18805">
        <property type="entry name" value="SF2_C_suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000269">
        <property type="entry name" value="ATP-dependent RNA helicase SUPV3L1, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.40:FF:000003">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3L, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000957">
        <property type="entry name" value="ATP-dependent RNA helicase SUV3L, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056377">
        <property type="entry name" value="DExH18_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055206">
        <property type="entry name" value="DEXQc_SUV3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050699">
        <property type="entry name" value="RNA-DNA_Helicase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022192">
        <property type="entry name" value="SUV3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041082">
        <property type="entry name" value="Suv3_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044774">
        <property type="entry name" value="Suv3_DEXQc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131">
        <property type="entry name" value="ATP-DEPENDENT RNA AND DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12131:SF28">
        <property type="entry name" value="DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23703">
        <property type="entry name" value="DExH18_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22527">
        <property type="entry name" value="DEXQc_Suv3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12513">
        <property type="entry name" value="SUV3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18147">
        <property type="entry name" value="Suv3_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="14" id="KW-1135">Mitochondrion nucleoid</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="18">
        <location>
            <begin position="435"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="19">
        <location>
            <begin position="594"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="191"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="17">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00080791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0584350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="957" mass="105631" checksum="2DC875EACD53CBFA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILA1</accession>
    <name>A0A8T0ILA1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Potassium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G218200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Potassium transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILA1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003855">
        <property type="entry name" value="K+_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053952">
        <property type="entry name" value="K_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053951">
        <property type="entry name" value="K_trans_N"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00794">
        <property type="entry name" value="kup"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540">
        <property type="entry name" value="OSMOTIC STRESS POTASSIUM TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30540:SF13">
        <property type="entry name" value="POTASSIUM TRANSPORTER 17-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02705">
        <property type="entry name" value="K_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22776">
        <property type="entry name" value="K_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="4 10" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="566"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="590"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="620"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="647"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter integral membrane" evidence="12">
        <location>
            <begin position="200"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="domain" description="K+ potassium transporter C-terminal" evidence="13">
        <location>
            <begin position="698"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="25"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU321113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF22776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0584564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="882" mass="97867" checksum="B9BC324C3FB0D18D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMC0</accession>
    <name>A0A8T0IMC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Two-component response regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_3G244100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMC0"/>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009736">
        <property type="term" value="P:cytokinin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17584">
        <property type="entry name" value="REC_typeB_ARR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000007">
        <property type="entry name" value="Two-component response regulator"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045279">
        <property type="entry name" value="ARR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43874:SF7">
        <property type="entry name" value="TWO-COMPONENT RESPONSE REGULATOR ARR10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="1 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="Response regulatory" evidence="9">
        <location>
            <begin position="32"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="10">
        <location>
            <begin position="200"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="440"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="440"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="7">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0584914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="594" mass="64675" checksum="2758CDA5ED5B8088" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP54</accession>
    <name>A0A8T0IP54_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_2G019800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08838">
        <property type="entry name" value="ArfGap_AGFG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000005">
        <property type="entry name" value="Arf-GAP domain and FG repeat-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044820">
        <property type="entry name" value="AGD14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46085:SF3">
        <property type="entry name" value="ARF GTPASE ACTIVATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46085">
        <property type="entry name" value="ARFGAP/RECO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="6">
        <location>
            <begin position="11"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="120"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="259"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="332"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="511"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="137"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="200"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="333"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="350"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="363"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="389"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="404"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="511"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="664" mass="72617" checksum="8E77F6A269731A33" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQI5</accession>
    <name>A0A8T0IQI5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G254600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQI5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11116" checksum="3591280BFE034608" modified="2022-10-12" version="1">MTVQECSHHACEKSDHMQRKEVITWRRRRCREGSDDGESEVSRSGGAGTWTPRFSTGMGSEQGRSWGIRDGGGGREGERVGPRGARGAEREVPGLAMAEGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRV8</accession>
    <name>A0A8T0IRV8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G036200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF969">
        <property type="entry name" value="INTEGRIN-LINKED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="146"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0585759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="448" mass="51246" checksum="B323603108ED1BE5" modified="2022-10-12" version="1">MTSNCCAFSCFSSCTRKCKRPSKEDLELSGPMNASSNSRYVTACTTLGEYATTSALPSSDPAPSGSSMERNESVEESIEGSKSHWSEVVKSDPSITDDELVKDNRAVFRELQSHPIWGGFFRTFGYALETPVAGMPGYIHVSSGKLIVGEKFAEGGQAELFHARVIWYKSKIIKYFLKRGYEWVMKVFKKGTSLRQLQSQWPLGYLQFRGELGSNSIDPKLVRYYCEVFFGILLEDGRFAFLMKREHKDLRKLIDQRMLEIGQGEGPFSKEDGELIMYKIACGMNWLHERNIIHRDLKASNVLCRVYGNAYQVYVADFECSIGVIGTGFWRAPEILQAIKDRMIYEKIEVFSKKADVYAYGMTCYEILTGKFPFGNHSNRDYDIVLNDGQLELPEYVEDWIDKIVKRCWNKNPIDRPSFIEILDLFANNSARVSNHIKKLKIRDDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS64</accession>
    <name>A0A8T0IS64_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallo-beta-lactamase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G055600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000534">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041516">
        <property type="entry name" value="LACTB2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050662">
        <property type="entry name" value="Sec-metab_biosynth-thioest"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23131:SF0">
        <property type="entry name" value="ENDORIBONUCLEASE LACTB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17778">
        <property type="entry name" value="WHD_BLACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="511"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="2">
        <location>
            <begin position="239"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="540" mass="58970" checksum="B978CE67A9E1101C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IU15</accession>
    <name>A0A8T0IU15_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Nucleolar complex protein 3 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G080000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CBF/MAK21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IU15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005612">
        <property type="entry name" value="CCAAT-binding_factor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011501">
        <property type="entry name" value="Noc3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016903">
        <property type="entry name" value="Nucleolar_cplx-assoc_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14428:SF5">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03914">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07540">
        <property type="entry name" value="NOC3p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleolar complex-associated protein 3 N-terminal" evidence="7">
        <location>
            <begin position="239"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="CCAAT-binding factor" evidence="6">
        <location>
            <begin position="598"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="66"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="154"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="442"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="77"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="197"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="442"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0586296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="922" mass="102748" checksum="3319FD6647D957B4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVS2</accession>
    <name>A0A8T0IVS2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G193000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the acetyltransferase family. ARD1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031416">
        <property type="term" value="C:NatB complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:protein-N-terminal amino-acid acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000034">
        <property type="entry name" value="N-alpha-acetyltransferase 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051646">
        <property type="entry name" value="NatB_acetyltransferase_subunit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45910:SF1">
        <property type="entry name" value="N-ALPHA-ACETYLTRANSFERASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="4">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0587810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="174" mass="20277" checksum="2F0C3280393D535A" modified="2022-10-12" version="1">MTTIRRFCCDDLLKFANVNVDHLTETFSMAFYQTYMARWPDYCHVAEAPNGSIMGYILGKVEGHGENWHGHVTAVTVAPEYRRQQLAKKLMIILEDITEKTYNGYFVDLFVRASNVPAITMYQKLGYSVYRRVLRYYSGEEDGLDMRKAMPRDVHKKSMIPLKRAITPEELEYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVT9</accession>
    <name>A0A8T0IVT9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Matrin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G117500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071011">
        <property type="term" value="C:precatalytic spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16165">
        <property type="entry name" value="OCRE_ZOP1_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000690">
        <property type="entry name" value="Matrin/U1-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003604">
        <property type="entry name" value="Matrin/U1-like-C_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041591">
        <property type="entry name" value="OCRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013085">
        <property type="entry name" value="U1-CZ_Znf_C2H2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040023">
        <property type="entry name" value="WBP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036236">
        <property type="entry name" value="Znf_C2H2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035622">
        <property type="entry name" value="ZOP1_OCRE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173">
        <property type="entry name" value="WW DOMAIN BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13173:SF10">
        <property type="entry name" value="WW DOMAIN-BINDING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17780">
        <property type="entry name" value="OCRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06220">
        <property type="entry name" value="zf-U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00451">
        <property type="entry name" value="ZnF_U1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57667">
        <property type="entry name" value="beta-beta-alpha zinc fingers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50171">
        <property type="entry name" value="ZF_MATRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Matrin-type" evidence="7">
        <location>
            <begin position="11"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="73"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="174"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="73"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="206"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="250"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0586791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="294" mass="32288" checksum="E42501C6D9295DCB" modified="2022-10-12" version="1">MTEYWVSQGKKWCDYCKIFIANNATSLRNHEIGQRHKEAMAQRLTTMRKDNIAKEKEKQQALKDLERIEQQAKRSYERDMAAAERLSGSANTSAQQIARPPEAPGGAPPAPAIPTPRSSQVNSYLKSDGNVNEWTYDEKSGYHFNAATGYYYDPNSGLYYSDILGKWTTQEEAHRASQKAHAEAGVAPAASTLSKQPSQTKDEPKISSNATSTSHAKPAVKTSTASQGPAPKQKTLPSKGVKGVASSLEINKRRRDEKTGPVSSEEAAALAAREAAKKRVLDREKSLLGLYQAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWY9</accession>
    <name>A0A8T0IWY9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Urea-proton symporter DUR3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">High-affinity urea active transporter DUR3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G228200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">High-affinity urea-proton symporter involved in the active transport of urea across the plasma membrane into root cells. May play an important role in urea uptake by plant cells at low external urea concentrations.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWY9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015204">
        <property type="term" value="F:urea transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11476">
        <property type="entry name" value="SLC5sbd_DUR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1730.10:FF:000006">
        <property type="entry name" value="Urea active transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="entry name" value="Sodium/glucose cotransporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031155">
        <property type="entry name" value="DUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46154:SF4">
        <property type="entry name" value="UREA ACTIVE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="287"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="332"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="383"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="429"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="457"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="528"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="587"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="618"/>
            <end position="642"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00059650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00072203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00079542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0588244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="716" mass="77632" checksum="C2E2AD0F38C7F1C8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXE9</accession>
    <name>A0A8T0IXE9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G198200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34364">
        <property type="entry name" value="WAS/WASL-INTERACTING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34364:SF1">
        <property type="entry name" value="WAS_WASL-INTERACTING FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="179" mass="19675" checksum="77BBE897144BC446" modified="2022-10-12" version="1">MSEPQNPPKLFLHKPKKASHPPGGEMGEQVVRVPVVQQPAAATAVPTAPLKPPFWYRYRAGVGALLLVNLGIGGYVLSRPKPVLDSQLHKGAIEPEPAKAKSAPEQVPVPVVAAAVAAPEWAPPPKVTISEEEQRQVLEWILQERRKVKTQNKAEKARIDEEKKMLKQFLRASHLPPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXT6</accession>
    <name>A0A8T0IXT6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Complex 1 LYR protein domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G169900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I LYR family. LYRM9 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXT6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd20269">
        <property type="entry name" value="Complex1_LYR_LYRM9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008011">
        <property type="entry name" value="Complex1_LYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045291">
        <property type="entry name" value="Complex1_LYR_LYRM9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36758">
        <property type="entry name" value="OS01G0342800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36758:SF1">
        <property type="entry name" value="OS01G0342800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05347">
        <property type="entry name" value="Complex1_LYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex 1 LYR protein" evidence="3">
        <location>
            <begin position="85"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0587511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="169" mass="18605" checksum="6D80921FCC160424" modified="2022-10-12" version="1">MKGVFGVGQSICCRAGGGEGSSTFGVAFAFARAWARWEEGEEGGGRGGRRERREEGEEGGGRGGRRERREEGEEGASMSMSMGGAVKQAYREVLKLIKRLPPQSQGYYSQYARENFITYSEPQDAATVRELLARAHRHSCWILNKYGVNEAAANKLKEICLTDHVQNPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1M5</accession>
    <name>A0A8T0J1M5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G275200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1M5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd03398">
        <property type="entry name" value="PAP2_haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.606.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052559">
        <property type="entry name" value="V-haloperoxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599">
        <property type="entry name" value="PEROXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599:SF1">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE TYPE 2_HALOPEROXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035871649" evidence="1">
        <location>
            <begin position="33"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="52962" checksum="C6B2816C322A79D6" modified="2022-10-12" version="1">MMVKLICTEMERFAGGLLVLALVLSPMIVVQAALPSDNVSVQWNVLLNKLFCTSSGLVHDPIIILANLNLAQWHGLLALKGTGACTKPEAVVAYASRKVLATYFVFDQNTLIDPLLANQLTALGLSETEKKLAKGLGEAVARRLISKSDPAYEFALPELRSAINANQAHPTPGLLRFLPNDTVFGPNALFVTHAIAFDSPYVIPYPNRFIEEYLGDLKPMAVPSDAWDKQYNLLKDVGRINWSGRTYEMNYTASLYLCPRQNTTYCLFIESFWTVAAMNILPKETSLDDIVEVFAKLSVALHDALVVVAAQKDGYWFWRPQMAFTAGDPRHPPIPDWLPYGRVIFTGEYPSGTTMSYAAAATVLQDYFGKKKVPFTVDGGGVFGGATCYLAGTPVKPRHFDSLWAAVEEAKRGRMYVGAHYKFSVDDGAEAGKRVAQYILKHWGDRPPQGVLPDTEYLKVHANLPKKSGDWDPLRFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J392</accession>
    <name>A0A8T0J392_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Glutathione S-transferase 3, mitochondrial</fullName>
            <ecNumber evidence="15">4.4.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Glutathione peroxidase MGST3</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="20">LTC4 synthase MGST3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_1G015200</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione = 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione</text>
            <dbReference type="Rhea" id="RHEA:75963"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:85236"/>
            <dbReference type="ChEBI" id="CHEBI:194498"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="17">
            <dbReference type="Rhea" id="RHEA:75964"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>leukotriene C4 = leukotriene A4 + glutathione</text>
            <dbReference type="Rhea" id="RHEA:17617"/>
            <dbReference type="ChEBI" id="CHEBI:57463"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:57973"/>
            <dbReference type="EC" id="4.4.1.20"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="16">
            <dbReference type="Rhea" id="RHEA:17619"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="14">Lipid metabolism; arachidonate metabolism.</text>
    </comment>
    <comment type="pathway">
        <text evidence="13">Lipid metabolism; leukotriene C4 biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion outer membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.20" evidence="15"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J392"/>
    <dbReference type="OrthoDB" id="410651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004464">
        <property type="term" value="F:leukotriene-C4 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006691">
        <property type="term" value="P:leukotriene metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.550:FF:000004">
        <property type="entry name" value="Microsomal glutathione S-transferase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.550">
        <property type="entry name" value="Membrane associated eicosanoid/glutathione metabolism-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050997">
        <property type="entry name" value="MAPEG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023352">
        <property type="entry name" value="MAPEG-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001129">
        <property type="entry name" value="Membr-assoc_MAPEG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10250:SF22">
        <property type="entry name" value="MICROSOMAL GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01124">
        <property type="entry name" value="MAPEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161084">
        <property type="entry name" value="MAPEG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0564">Palmitate</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00037884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00037916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00039056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00049298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00069748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00075145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00076908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0589351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="148" mass="16474" checksum="E0238D45ECF2F740" modified="2022-10-12" version="1">MAVEMVKGYEWVLMALIANVLVTNVWMMFKVGMARTKYKVSYPAMYAVESENKEAKLFNCIQRGHQNTLEFMPTFLALLLLGGLQYPLVAAGFGALYTLARIQYFRGYSTGVALARYSGGARAQWIGLLGLLCCTFALALHQVFPTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J499</accession>
    <name>A0A8T0J499_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G093600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J499"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044784">
        <property type="entry name" value="At1g01640-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47274:SF10">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47274">
        <property type="entry name" value="BTB/POZ DOMAIN CONTAINING PROTEIN, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="BTB" evidence="9">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="227"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="496"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="267"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="500"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="523"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="545" mass="60813" checksum="7E15831B407FE05F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J585</accession>
    <name>A0A8T0J585_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Smr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G068900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J585"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14371">
        <property type="entry name" value="CUE_CID7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041806">
        <property type="entry name" value="CID5/6/7_CUE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013899">
        <property type="entry name" value="DUF1771"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053242">
        <property type="entry name" value="PAM2-like_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46651">
        <property type="entry name" value="POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46651:SF1">
        <property type="entry name" value="SMALL MUTS RELATED FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08590">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01162">
        <property type="entry name" value="DUF1771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SMR domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="2">
        <location>
            <begin position="537"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="619" mass="66929" checksum="6ACA4CB290843AA3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6N2</accession>
    <name>A0A8T0J6N2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G185400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6N2"/>
    <dbReference type="OrthoDB" id="2018252at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037501">
        <property type="entry name" value="TPLATE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36029:SF1">
        <property type="entry name" value="PROTEIN TPLATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36029">
        <property type="entry name" value="TSET COMPLEX MEMBER TSTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1097"/>
            <end position="1107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1152" mass="127319" checksum="127DB33BF4A0CCD3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6N8</accession>
    <name>A0A8T0J6N8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Intraflagellar transport protein 122 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G185800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6N8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030991">
        <property type="term" value="C:intraciliary transport particle A"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097730">
        <property type="term" value="C:non-motile cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035721">
        <property type="term" value="P:intraciliary retrograde transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061512">
        <property type="term" value="P:protein localization to cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056153">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039857">
        <property type="entry name" value="Ift122/121"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764:SF4">
        <property type="entry name" value="INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12764">
        <property type="entry name" value="WD REPEAT DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23381">
        <property type="entry name" value="Beta-prop_IFT122_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="IFT122 first beta-propeller" evidence="8">
        <location>
            <begin position="2"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="55"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="24321" checksum="99202A2E45F9254E" modified="2022-10-12" version="1">MRAVVAWTDHVPEHDGVRSVCFDIAFRPDGSHLIAAVGSRVLMYDAADGDLLHSLKGHKDEVYCVAYSRDGKRFASGGADKTIIIWTHKAEGILKYSHGDSIQCLAYNPVTQQLASGTATDFGIWSPEQKSVSKHKAPSKVLCAAWTADGQHLALGMYNGHISICDKSGVEQAVVERPGPVWTLQWNTLQNKTSDTLAVGCWDSTLSFYDLSGWEEQEHRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J823</accession>
    <name>A0A8T0J823_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G203600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J823"/>
    <dbReference type="OrthoDB" id="2789670at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20618">
        <property type="entry name" value="CYP71_clan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.630.10:FF:000126">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944">
        <property type="entry name" value="CYTOCHROME P450 98A9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47944:SF16">
        <property type="entry name" value="CYTOCHROME P450 FAMILY 1 SUBFAMILY A POLYPEPTIDE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0349">Heme</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="469"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR602401-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="533" mass="61141" checksum="EC0B0E01D1C5AE1C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J889</accession>
    <name>A0A8T0J889_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G208600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J889"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12647" checksum="9036088B4D2D0FAA" modified="2022-10-12" version="1">MAEGLIEFVQQLNYGNPSLSLDHVEDTYTEWTVWEVPAHLRTKYPANFQNKGLEFDLHRRTWTKSPPEAFKADIARILHSKLALKGSSWDQFVRDLVGDVNKARRAYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J986</accession>
    <name>A0A8T0J986_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G195400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J986"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12005" checksum="103DF9382C0D5E28" modified="2022-10-12" version="1">MPPDSFHCWLVKCVNTFLYYVPFSVLDHVIEKSVDILKQRCACHMCCGSSLFDSVMATIWSGRFHFIAVAKGIAGIFLVLNRYPSPRKDPSPILYVSQNIFISTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAB6</accession>
    <name>A0A8T0JAB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_1G234000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Component of the 19S regulatory particle (RP/PA700) base subcomplex of the 26S proteasome. The 26S proteasome is composed of a core protease (CP), known as the 20S proteasome, capped at one or both ends by the 19S regulatory particle (RP/PA700). The RP/PA700 complex is composed of at least 17 different subunits in two subcomplexes, the base and the lid, which form the portions proximal and distal to the 20S proteolytic core, respectively.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAB6"/>
    <dbReference type="OrthoDB" id="1937997at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000008">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000027">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000034">
        <property type="entry name" value="26S protease regulatory subunit 10B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050221">
        <property type="entry name" value="26S_Proteasome_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032501">
        <property type="entry name" value="Prot_ATP_ID_OB_2nd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23073">
        <property type="entry name" value="26S PROTEASOME REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16450">
        <property type="entry name" value="Prot_ATP_ID_OB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-0647">Proteasome</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="13">
        <location>
            <begin position="165"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="18"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0592206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="392" mass="43992" checksum="88454D6A257F67BE" modified="2022-10-12" version="1">MADPEVVRADYRRKLLQHKEIDSRLRTLRDNVKTARKEFDKTEDDLKALQSVGQIIGEVLRQLDSERLIVKASSGPRYVVGCRNKVDKEKLVAGTRVALDMTTLTIMRALPREVDPVVYNMLHEDPGNISYSAVGGLSDQIRELRESIELPLMNPELFLRVGIKPPKGVLLYGPPGTGKTLLARAIASNIDANFLKVVSSAIVDKYIGESARLIREMFSYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQLDGFDQLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRTEILKIHASGITKHGEIDYEAIVKLAEGFNGADLRNVCTEAGMFAIRADRDFVVQEDFMKAVRKLTDAKKLESSAHYSTDFGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB78</accession>
    <name>A0A8T0JB78_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G224000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035861407" evidence="1">
        <location>
            <begin position="24"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6308" checksum="439BE3AE0047BE56" modified="2022-10-12" version="1">MAILLTRACVVSTRVFWVTVVLSESEREIDNYIQNDFIVRGQHIQVVLRWNVCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB94</accession>
    <name>A0A8T0JB94_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="2 6">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G234400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Cytokinin-activating enzyme working in the direct activation pathway. Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>9-ribosyl-trans-zeatin 5'-phosphate + H2O = trans-zeatin + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48564"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16522"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:87947"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O = N(6)-dimethylallyladenine + D-ribose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:48560"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17660"/>
            <dbReference type="ChEBI" id="CHEBI:57526"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="3.2.2.n1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="2 6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB94"/>
    <dbReference type="OrthoDB" id="414463at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016799">
        <property type="term" value="F:hydrolase activity, hydrolyzing N-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00730">
        <property type="entry name" value="Rossman fold protein, TIGR00730 family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31223:SF70">
        <property type="entry name" value="LOG FAMILY PROTEIN YJL055W"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102405">
        <property type="entry name" value="MCP/YpsA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0592209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="244" mass="26333" checksum="C39DEE1504935CBA" modified="2022-10-12" version="1">MGAKQMMEQETPAVVVPYVEKEKMMMSSCPSKRFKKICVFCGSSSGKKGVFSNEALNLGRELVNRKIDLVYGGGSIGLMGQVAHTVKSGGGHVVGVIPKALIGAELTGSTVGELIAVTDMHQRKAEMARQADAFIALPGGYGTLEELVEVITWNQLGIHKKPVGLLNVDGFYDTLLNFFDKQLEEEFFDNSARSIVVSAPTASELLDKLEAYSRPLAYGPKLCWEVERPCGLGYSTNPIAGLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC42</accession>
    <name>A0A8T0JC42_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G287100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC42"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035733628" evidence="1">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6163" checksum="C8725FE9945373B5" modified="2022-10-12" version="1">MGFCAFTISLAPFLIDAHISVCCTFLTSCRVLHGLSVGKCRGYALAVIFTGIDIRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDH3</accession>
    <name>A0A8T0JDH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histone deacetylation protein Rxt3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G302700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.20">
        <property type="entry name" value="LCCL-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036609">
        <property type="entry name" value="LCCL_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013951">
        <property type="entry name" value="Rxt3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08642">
        <property type="entry name" value="Rxt3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69848">
        <property type="entry name" value="LCCL domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="768"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="266"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="910" mass="101730" checksum="E9DD3114CAE842F0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3W7</accession>
    <name>A0A8T0G3W7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G024700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3W7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="entry name" value="paralog of FGE (formylglycine-generating enzyme)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051128">
        <property type="entry name" value="EgtD_Methyltrsf_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43397:SF1">
        <property type="entry name" value="ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="C-type lectin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine-specific methyltransferase SAM-dependent" evidence="5">
        <location>
            <begin position="11"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="4">
        <location>
            <begin position="540"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfatase-modifying factor enzyme-like" evidence="4">
        <location>
            <begin position="694"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="489"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0553605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="768" mass="87615" checksum="A1B68E237AABA6D7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4T6</accession>
    <name>A0A8T0G4T6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyanovirin-N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G049300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4T6"/>
    <dbReference type="OrthoDB" id="1911093at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011058">
        <property type="entry name" value="Cyanovirin-N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08881">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01111">
        <property type="entry name" value="CVNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51322">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035908062" description="Cyanovirin-N domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Cyanovirin-N" evidence="2">
        <location>
            <begin position="32"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="162" mass="17070" checksum="3D8FDC26E44127EC" modified="2022-10-12" version="1">MVWQRASALAAAGLLCVLALLSGAQAQLQCEGFAASCNTYSFGADGIFRAQCRDHAGRYVAASVNPNPYISNVDGHLIDGANFLESCVASGVGTSENPDVQVRIYATCTKINGALSLTHYDINRKVFNNNGNLVWNNCHRTAPIKATPGLTLAGGGRKLLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G634</accession>
    <name>A0A8T0G634_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L18a</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G020600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G634"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000001">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00273">
        <property type="entry name" value="Ribosomal_eL20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028877">
        <property type="entry name" value="Ribosomal_eL20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023573">
        <property type="entry name" value="Ribosomal_eL20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021138">
        <property type="entry name" value="Ribosomal_eL20_eukaryotes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10052">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01775">
        <property type="entry name" value="Ribosomal_L18A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002190">
        <property type="entry name" value="Ribosomal_L18a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160374">
        <property type="entry name" value="RplX-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL20" evidence="5">
        <location>
            <begin position="10"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0553559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="181" mass="21628" checksum="F85DF99A25E63FAC" modified="2022-10-12" version="1">MMLVWVLQFHQYQVVGRALPTPAKETPKAYRMKLWATDEVRAKSKFWYFLRKLQKVKKSHGQLLAINEIFEKYPTTIKNYGIWVRYQSRTGYHNMYKEYRDLTLNGAVEQMYDEMASRHRVRSPCIQIIKTATIPVSLCKRENTKQFHDSKIKFPLTYRKIRPPTRSLKTTYKASRPNTFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7V3</accession>
    <name>A0A8T0G7V3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G160700</name>
        <name evidence="3" type="ORF">KC19_12G161800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7V3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274436" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="116" mass="12056" checksum="E558ADD973307CDF" modified="2022-10-12" version="1">MNPFLIIFVMSSLIPNALDSTSSLISGLAPNSADAISCTPGFCAFSTDTVTACPLPTFSWKCTRPTGNRKKSPVFSFAANSFPAVSTNPTCTSPFSTVITSDALGCVWGGTRPPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7Z4</accession>
    <name>A0A8T0G7Z4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G007100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7Z4"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47556">
        <property type="entry name" value="SEC14P-LIKE PHOSPHATIDYLINOSITOL TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47556:SF1">
        <property type="entry name" value="SEC14P-LIKE PHOSPHATIDYLINOSITOL TRANSFER FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="153"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="34517" checksum="E772742084BC57D7" modified="2022-10-12" version="1">MAIVRAASRALLPTFRLLCCGQHLLSHFDSSTVRTVRQVDKLAFGRGDLKNHGTSTDLLGHNARRCYSAQATHQSIEAAPVPPDYQTYVDRVKARLETERADLPVGKNGRDDEDLLLWFLRDRNFDVDAAVAKLVEALEWRREFGVGEITEASVSKVASIGEAYVHSYPAKDGRPVIIVISSKQFPNDERLIETRQKHCVYLIEKALTQLSPGGESFLGIFDLRGFQPKNGDLKFVNFLIDVFFKYYPKRLGQVLFVDAPFIFQPGWRMAKPLFGKYAALVQFCSADDVRNDYFTPDTVPEIFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G831</accession>
    <name>A0A8T0G831_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G167600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G831"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008889">
        <property type="entry name" value="VQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039609">
        <property type="entry name" value="VQ_15/22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33179:SF83">
        <property type="entry name" value="VQ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33179">
        <property type="entry name" value="VQ MOTIF-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05678">
        <property type="entry name" value="VQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VQ" evidence="2">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="368" mass="39539" checksum="175849F2E27AADFF" modified="2022-10-12" version="1">MQQVDDVYREGKQGRPAASPTSVLEEDPLVVGSWSMWDLSLPIDSPSVSHHASPIRTSPLRSSMSSPLRDAMHLTSKRGAEGNNNSNSAGSRSLVETLQNCLTSLPQSTNMGDSVGRSLSDPNGAPSSATTSRQLSSRPPGKRRPRASRRTPTTILETNPSEFKDMVQKLTGIPSATPAGVPVRPQPQRASANHLVRPETLRSIRRLPPISSPPRPPITPAPITVLQHSQQNNTSPVLAAMTPTALKREFPEESSSSPLYGSYESVMKRAMSAPTTSMESWWSDNDKPRGPSMTNLNPELPFTMSSGDALTNAILSAASGTTASPDYARLDSADGQLAQEEQEFAFAQIEIESWLSAQDHASAESMCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8H9</accession>
    <name>A0A8T0G8H9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G022700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8H9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="158" mass="17617" checksum="6641CD32C31853AB" modified="2022-10-12" version="1">MPHHSTKPHPPSNSNYTAHNIISTRKPNSIASTKPTSPPTITSIAPHLGHPNAVLQPQRSPSFFPTRSPLLTYHEWRKPIPIAHFWNSHDPLCHLSLPHQSQRQLGLPCPANTPLRTIVMGIPITHFWSSSSLTFQANNASKTYAQSSEDETGRHILH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G916</accession>
    <name>A0A8T0G916_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Legumain prodomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G123300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G916"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21115">
        <property type="entry name" value="legumain_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.130:FF:000001">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000005">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043577">
        <property type="entry name" value="AE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048501">
        <property type="entry name" value="Legum_prodom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046427">
        <property type="entry name" value="Legumain_prodom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000">
        <property type="entry name" value="HEMOGLOBINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000:SF42">
        <property type="entry name" value="LEGUMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20985">
        <property type="entry name" value="Legum_prodom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500139">
        <property type="entry name" value="AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035874418" description="Legumain prodomain domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Legumain prodomain" evidence="10">
        <location>
            <begin position="375"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0554834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="53988" checksum="B07777D5F762B7BD" modified="2022-10-12" version="1">MASTRGLLLALLLSFCVVSALGRTLPWDDKIVMPTEEEDDKGEQGTRWAVLIAGSSGYWNYRHQADVCHAYQILKRGGLKDENIIVFMYDDIAYDPENPYPGKIINKPDGPDVYEGVPKDYTGEDVTVSNFYAAILGDKSAIKGGSGKVVDSGPNDHIFIYYTDHGGPGVLGMPTYPNLYADDFVDTLKKKAAAGTYKELVIYLEACESGSIFEGLLPEGLNIYVTTASNAEESSWGTYCPGMYPPPPPEYDTCLGDLYSVAWMEDTEKENLKKETLEDQYVIVKARTSNHNTYSTGSHVMQYGDIHIDVEELERYLGFDPANENVTKPELPESLSSNFEILTHVPQREADLLHLKHKYYKAEKGSLRKSLAGRQLSRTIVHRKHLDNSVKLIGEILFGSENGLEKLTAVRPAGTVVVDDWACLKGMVRTFEASCGPLTQYGMKHMRAFANICNAGIDTAKMSLASSKACTSSPTAGFGLWSPVTSKFSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9I5</accession>
    <name>A0A8T0G9I5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G007700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9I5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="13206" checksum="15268A413988988B" modified="2022-10-12" version="1">MVQQLRLLRWAYSCRRHLDPDFLVLNFLSLVWANCVVTVSHIQVLKSFSVMVNHLKSFSSIYCKMWSHRSEMYYWTTGPGGFQQRWYEVKFDFPPPLNFSHDSRVCIIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAD0</accession>
    <name>A0A8T0GAD0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G187800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48210">
        <property type="entry name" value="OS05G0352800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48210:SF1">
        <property type="entry name" value="OS05G0352800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="11910" checksum="F42D78A9F61824FF" modified="2022-10-12" version="1">MEEYQVEERKQAAADALMHYSQFAMVCIGEGVAPSKLRLHLLKELSGMPSTLRKETPQQGSPSSASNATTADRADRASSSSGATAAAAAAAAAAAAAAADSQVDRAYIPYHDRGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAF4</accession>
    <name>A0A8T0GAF4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exonuclease V</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G077600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EXO5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAF4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045145">
        <property type="term" value="F:single-stranded DNA 5'-3' DNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036297">
        <property type="term" value="P:interstrand cross-link repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019190">
        <property type="entry name" value="EXOV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14464:SF4">
        <property type="entry name" value="EXONUCLEASE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09810">
        <property type="entry name" value="Exo5"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="151"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="499"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0554262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="520" mass="58052" checksum="55A36A5829285F2D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCL6</accession>
    <name>A0A8T0GCL6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G179400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000246">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="GH_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="GLYCOSYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353:SF36">
        <property type="entry name" value="LP05116P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0555578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="515" mass="58277" checksum="3213234D692C1BA4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDQ9</accession>
    <name>A0A8T0GDQ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G163100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11690" checksum="CF9C0A5271765A63" modified="2022-10-12" version="1">MAPLDRARPEINPQEPRRMLHAHAVAESEPNHRVRSLQINLSQVKLRWMRLSHVAHHHDASSMICPCPLFLLSHRWSHLGCGGTIEHDISCVAVGPGCLGLRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDX3</accession>
    <name>A0A8T0GDX3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G112100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035823819" description="Secreted protein" evidence="2">
        <location>
            <begin position="18"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="33"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="11103" checksum="77F7C1F38B730413" modified="2022-10-12" version="1">MFIIMLRFSMFIYTLSTKRLRVDYSAANEHESSTSYSLSISTTRKRNPKPLETPHQFRNEVFQHSILLRQTNNESFSPHSLSTKQQRKRNPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEZ1</accession>
    <name>A0A8T0GEZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G101800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12959" checksum="1FD316CDF9C6A5DB" modified="2022-10-12" version="1">MSESTNRSSVVLANSLKVTFENHCEFSDILEMACFYWLGFVVCRAHVAPVDLRRYLRSCKILRCNRQIWNDLNILVFLVYVYHARIHPVSPPHSLLLLMDTLKNPRRPSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFN1</accession>
    <name>A0A8T0GFN1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G131800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFN1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="14313" checksum="C30558E606AA72A0" modified="2022-10-12" version="1">MSNHDSNPSQLRTLHVNSHGRCVQILRITSIELHFEEVIAHIHGRRRFKKPPDNGFSNTKPELKNLNPTERPLQQTKYLRAIKTIRQIRTYCKDQQRERMMEGKLLAVLLQKSSALTAETKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHF9</accession>
    <name>A0A8T0GHF9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G110400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF93">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="462"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="487"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="529"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="557"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="581"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="616"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="646"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="711"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="738"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="48"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="176"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="283"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="298"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="803" mass="89606" checksum="20166F6F6DE907FD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI57</accession>
    <name>A0A8T0GI57_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone deacetylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G160200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI57"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000118">
        <property type="term" value="C:histone deacetylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0040029">
        <property type="term" value="P:epigenetic regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09992">
        <property type="entry name" value="HDAC_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="entry name" value="Histone deacetylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="HDACs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625:SF11">
        <property type="entry name" value="HISTONE DEACETYLASE 14, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10625">
        <property type="entry name" value="HISTONE DEACETYLASE HDAC1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="Arginase/deacetylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histone deacetylase" evidence="1">
        <location>
            <begin position="90"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="46728" checksum="4EB0C3C50BDC0563" modified="2022-10-12" version="1">MAMAPCCVKGMVAVSRVGKCRDLIGTRKVEILNQVNQKRRQLAVRCDADSNASASTSRRPRELLVPVSQLVEARVIFAAAPAMGHNQEGHPECNARVPSILEALEKGELTPEFRGKEVLRIQNFKAASQEDVAAVHAMGYVKGLERAMQKAEDEGLIFLDNSGPTYATQSTYYESMMAAGASLALVDSVVAASKETKNPPVGFALVRPPGHHAVPAGPMGFCVFGNIAVAARYAQQVHGLQRVFIIDYDVHHGNGTNDAFYNDPDIFFLSTHQDGSYPGTGKMTEVGAGPGEGSTLNLPLPGGSGDETMAYVFEEVIVPAAQRFKPDIILVSAGFDAHVQDPLAGMQFTTGTYYRLASDIKRLAHELCGGRCIFFLEGGYDLKSLSNSVADSFRAFLGDKSLSSRLDNPAVLYDEPSLYARQAIDKIRSIHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI93</accession>
    <name>A0A8T0GI93_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_11G163000</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI93"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000590">
        <property type="entry name" value="PR5-like receptor kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000415">
        <property type="entry name" value="receptor-like serine/threonine-protein kinase NCRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="454"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="514"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="823"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="15">
        <location>
            <begin position="831"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0557869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="866" mass="96108" checksum="E66DDC6B4B2F60A3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ60</accession>
    <name>A0A8T0GJ60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G106700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="3">
        <location>
            <begin position="259"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="108"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="217"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="233"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0557162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="493" mass="52161" checksum="ECAF03F7637AC66F" modified="2022-10-12" version="1">MNNACCQSAMSVAGVRAAALGSRNLFRLQRQCKFLLGAKGSPHPLTARSSLPHFYWPGATRPTQRSTRAPSLLLAQCSLQDQFPPATTYVLLNTKECADGSVMFKFGSTEQQEQQPEQSPKDLSNGASTEEIKSSDSADRSSVNGSRNNSIADNSVASADVLSDFDDVPDAASLSDLAHGAEELAQELNMKEDEQKAVSSSNEEQVLSEAASDTADKTTSGGNGESNIATPTGSDGSDSSGIGIKDDKVNDDMMFNSAAAMIPHPDKVKTGGEDAYFIDGTRWVGVADGVGGWALSGVNAGHYARELMWNCAERARKVGSTSDPKSVLIYAAKRTKSTGTAATLIASLYDQTLRVANIGDSGFVVVRDSTVVARSEPMVRGFNFPYQIGTGGDDPELAEVYDVQVQKNDVVILGSDGIWDNLFEQQIIEIVSSVQKGGGGPEVVAKQLVTMANKTGLRKQGMSPFAAAAHTAGYDSYFGGKLDDTTAVVSYVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKK7</accession>
    <name>A0A8T0GKK7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peroxin/Ferlin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G150700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VPS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098588">
        <property type="term" value="C:bounding membrane of organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045053">
        <property type="term" value="P:protein retention in Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006614">
        <property type="entry name" value="Peroxin/Ferlin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010482">
        <property type="entry name" value="TECPR1-like_DysF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026847">
        <property type="entry name" value="VPS13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056748">
        <property type="entry name" value="VPS13-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026854">
        <property type="entry name" value="VPS13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009543">
        <property type="entry name" value="VPS13_VAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009291">
        <property type="entry name" value="Vps62"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166:SF137">
        <property type="entry name" value="PLECKSTRIN HOMOLOGY (PH) DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16166">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06398">
        <property type="entry name" value="Pex24p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25037">
        <property type="entry name" value="VPS13_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12624">
        <property type="entry name" value="VPS13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25036">
        <property type="entry name" value="VPS13_VAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06101">
        <property type="entry name" value="Vps62"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00693">
        <property type="entry name" value="DysFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peroxin/Ferlin" evidence="5">
        <location>
            <begin position="3128"/>
            <end position="3189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="740"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1202"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1683"/>
            <end position="1739"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2016"/>
            <end position="2054"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3136"/>
            <end position="3159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="3811"/>
            <end position="3847"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="4362"/>
            <end position="4405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1127"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1140"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1153"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1225"/>
            <end position="1235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1312"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1697"/>
            <end position="1715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="2035"/>
            <end position="2050"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="3137"/>
            <end position="3148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="4372"/>
            <end position="4384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="4392"/>
            <end position="4404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0560051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="4611" mass="510862" checksum="3E830277C4256594" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKS3</accession>
    <name>A0A8T0GKS3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G057800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKS3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="8083" checksum="56716146E92B283A" modified="2022-10-12" version="1">MSSSSNFELDKSVSEVREIPAPSRSERSRETANPRLEKQGRVEKQALVTSLLEFIDWRHLELPESDDHCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM29</accession>
    <name>A0A8T0GM29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_10G116000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM29"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000008">
        <property type="entry name" value="ATP-dependent RNA helicase RhlB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="158"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="349"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="18"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="61"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00037449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0559585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="548" mass="59709" checksum="D5A78221ED00162F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMU6</accession>
    <name>A0A8T0GMU6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G077200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMU6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="66" mass="7872" checksum="313C14AD04369FEE" modified="2022-10-12" version="1">MHLINQLAGACGRRRRGGQKEKSEYGRLAWERRWKEFLCGGVFCVAWCGARRRDCRVSRRREQFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPZ6</accession>
    <name>A0A8T0GPZ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Transmembrane protein 208</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G002600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM208 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPZ6"/>
    <dbReference type="OrthoDB" id="276296at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008506">
        <property type="entry name" value="SND2/TMEM208"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13505:SF7">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05620">
        <property type="entry name" value="TMEM208_SND2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="142"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0560657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="174" mass="20450" checksum="16A202D67B4ECCF4" modified="2022-10-12" version="1">MANKGAKKRKEENEKHMAFLRNVILISNVIYVVLRFGLRFRSLWWFHGVMFIFTSVIYKLVYDQLAGMAKPEIDEATGEILDGGFDMKTGGLCSYMHDLLYITSFLQVASILSDKFWWLYLVIPGFGIYKVWPYFYSAFLKPSEPEGPMDEREKKRLEKAERRANRPKFGKVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRK2</accession>
    <name>A0A8T0GRK2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_9G046300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 18">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRK2"/>
    <dbReference type="OrthoDB" id="3638488at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21742">
        <property type="entry name" value="MobB_NDR_LATS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05599">
        <property type="entry name" value="STKc_NDR_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000042">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000106">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000102">
        <property type="entry name" value="Non-specific serine/threonine protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000961">
        <property type="entry name" value="AGC-kinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059233">
        <property type="entry name" value="MobB_NdrA/B/Cbk1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017892">
        <property type="entry name" value="Pkinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050839">
        <property type="entry name" value="Rho-assoc_Ser/Thr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988:SF76">
        <property type="entry name" value="CHROMOSOME UNDETERMINED SCAFFOLD_135, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22988">
        <property type="entry name" value="MYOTONIC DYSTROPHY S/T KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00433">
        <property type="entry name" value="Pkinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00133">
        <property type="entry name" value="S_TK_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51285">
        <property type="entry name" value="AGC_KINASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="129"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="AGC-kinase C-terminal" evidence="15">
        <location>
            <begin position="436"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="516"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="92"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="13"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="294"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="549"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0561217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="591" mass="68327" checksum="E2F381A4F74C6A26" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS20</accession>
    <name>A0A8T0GS20_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (quinone)</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_9G148500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + NADPH + H(+) = a quinol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS20"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="5"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0562461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="202" mass="21617" checksum="EA233C70682E0BCC" modified="2022-10-12" version="1">MAVKLYIVYYSMYGHVEKLAREIQKGANSVEGVEAVLYQVAETLPEEVLSKMYAPPKSVDVPFIEAKDLAEADGFLFGFPTRFGMMAAQFKSFLDATGGLWRTQSLAGKPAGLFISTASQGGGQETTALTAITQLTHHGMIFVPIGYTGGAGMSTMDEARGGSPYGSGTLAGDGSRQPSKLELETAFHQGKYTAEITKKLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GST4</accession>
    <name>A0A8T0GST4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G046000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GST4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="171" mass="18779" checksum="D95547F92C656243" modified="2022-10-12" version="1">MMMMMMSAARGGKDGDKAPRAARARPLKIVPRAERLQARFSLSLPLPLSLSPQLRAPSLCKSLRFELPGYGDWALPSAATPRAAPQNRRSPPPLRPASSHSPPIVVPSSPPRLPPQRFRLGSLSGSFQLVVMLPGSWRRMPVSGGIRQKGCTPKPVFDSKIVPWRMFVRVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GT94</accession>
    <name>A0A8T0GT94_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G182200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GT94"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035767425" evidence="1">
        <location>
            <begin position="19"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6002" checksum="14DC29AE25D6E4FD" modified="2022-10-12" version="1">MAILTYMTLLARNAVSCAKAVMCQSSYVTAISKHTTSLAHFKIRVGGTEQNGELAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTM8</accession>
    <name>A0A8T0GTM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G088100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035721279" evidence="1">
        <location>
            <begin position="16"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6215" checksum="948C32508F1868B1" modified="2022-10-12" version="1">MVFFLNLVGVVWVVALVHVCCEGWVCLSVVRGWNRVAHLGLGCCGFVVCDRSFRVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUF3</accession>
    <name>A0A8T0GUF3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G161800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19145">
        <property type="entry name" value="AKR_AKR13D1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050791">
        <property type="entry name" value="Aldo-Keto_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625">
        <property type="entry name" value="AFLATOXIN B1 ALDEHYDE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43625:SF81">
        <property type="entry name" value="OS01G0618100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="19"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="338" mass="37283" checksum="C4B7B0B2040F59E2" modified="2022-10-12" version="1">MQQVPRRKLGSQGLEVSALGLGCMGLSPFYGKPVEEEHGIAVIQQAFNNGVTFFDTSDVYGPHTNEKLLGLALKGLPREQVQIATKFGADVFMQIRGDSEYVRQACEDSLKRLGVDYIDLYYQHRVDTRVPIELTVGAMKKLVEEGKVKYIGLSEAGPDTIRRAHAVHPITAVQIEWSLWTRDIEETVVPVCRELGIGIVPYSPLGQGFFSGKAVVEKHSEYASQLNAVRPRFQDENLEENKVLYERVAALAKKYNCTPGQLALAWVLHQGNDVVPIPGTTKIPNLNENIGAAFVNLTEVEVQEVAAAVPLHDVAGERYIEAVAKLSWNNVTTPPFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUP8</accession>
    <name>A0A8T0GUP8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G028400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUP8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007877">
        <property type="entry name" value="DUF707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210">
        <property type="entry name" value="OS06G0731900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210:SF47">
        <property type="entry name" value="OS07G0564800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05212">
        <property type="entry name" value="DUF707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="420" mass="47425" checksum="B207BE6A00A0CB45" modified="2022-10-12" version="1">MSQALGKWLKQTPVILPMFTPSPSGKSLVVSSKLKKLVWFTKLFYLALLVMAITFIVSTIVVNEQSFKKAIVDRLSGTLQVSGSDECYLTKAHCSRGGGEALPKGIIVETTDLRLRSLVMEKDSKFQPKEAVAKNLLAMAVGIKQKKVVNDIVQKFPLSNFTIMLFHYDGVVDQWHDLAWSNQSIHIVGLHQTKWWFAKRFMHPDIVAEYNYVFLWDEDLGVEHFHADKYLEIMEAEGFEISQPALDPASSDIHHMLTRRQASGRAHTMVMANHGTTLCNKDSNGPPCTGYVEVMAPVFSKAAWRCIWHMVQNDLVHGWGIDFKIGYCAQGVRSEKVGVIDAEYILHKGIPSLGGPRQKNVTTAEQKKQYNNSLRSKVRKRSGAELTTFLQRWKKAAEEDASWMDPFPPRNDSSANYHKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXJ9</accession>
    <name>A0A8T0GXJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP synthase subunit epsilon, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G175100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ATPase epsilon family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXJ9"/>
    <dbReference type="OrthoDB" id="269124at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042776">
        <property type="term" value="P:proton motive force-driven mitochondrial ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12153">
        <property type="entry name" value="F1-ATPase_epsilon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.20">
        <property type="entry name" value="ATP synthase, F1 complex, epsilon subunit superfamily, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006721">
        <property type="entry name" value="ATP_synth_F1_esu_mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036742">
        <property type="entry name" value="ATP_synth_F1_esu_sf_mt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448">
        <property type="entry name" value="ATP SYNTHASE EPSILON CHAIN, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12448:SF0">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT EPSILON, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04627">
        <property type="entry name" value="ATP-synt_Eps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48690">
        <property type="entry name" value="Epsilon subunit of mitochondrial F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="82" mass="8886" checksum="D2AA59D05271EDA2" modified="2022-10-12" version="1">MAQAQAAAAPAVQTGSAYWRAAGMTYIGFANLCAVVVRKCQKEPFKSQSLSREKVHYKYAPYADGAQQKPEYRGVDAGKEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ54</accession>
    <name>A0A8T0GZ54_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G150200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ54"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035729376" evidence="1">
        <location>
            <begin position="16"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6349" checksum="CF255955950ADCAE" modified="2022-10-12" version="1">MLFLSGQIFEHLVLALSCPCGYYYYKSLQIDSTICISTLIGRHVLPMWALLQLVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H056</accession>
    <name>A0A8T0H056_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="21">Ketol-acid reductoisomerase, chloroplastic</fullName>
            <ecNumber evidence="7">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18">Acetohydroxy-acid reductoisomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="ORF">KC19_8G090400</name>
    </gene>
    <organism evidence="25 26">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="25" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="25">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 22">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="25">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="7"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H056"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:L-valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000015">
        <property type="entry name" value="Ketol-acid reductoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000146">
        <property type="entry name" value="Ketol-acid reductoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371:SF1">
        <property type="entry name" value="KETOL-ACID REDUCTOISOMERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 22" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16 22" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12 22" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 22" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0521">NADP</keyword>
    <keyword evidence="15 22" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="26" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="23">
        <location>
            <begin position="103"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="24">
        <location>
            <begin position="302"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="24">
        <location>
            <begin position="451"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="513"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00030209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00030593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00047612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00049021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00074052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="24">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0564187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="589" mass="63336" checksum="54FFDB230CE84594" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0V0</accession>
    <name>A0A8T0H0V0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G135900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0V0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="396" mass="43531" checksum="7D77E5B61479C5DE" modified="2022-10-12" version="1">MSGKSELPVPPTSKPPVDGPKTQWIKQVVNAAGAAHKFEKPIVARRAVQEGTDRLRANGRNGSEAKYKQNQPPELEFKLNPHLTGCSQFHADSSTQIQEDSDHEVLKITHKALYERLNMYGFVFVLLGSISFVAILQPPGGFDNDGHMRSNTLVSCFMFFSTLSFLFTFIGLFGVVVGFLTLFRPAFYLKFEIRASSAKFSQSGSSQVLKSLPSSDISGSSHNNSLSSDRSRSLLYNASPGGLHNKEGMDDLTVMAKLLWDNLERMWRLRIYLIFSLVLIVSAFGCGVFAIIGGSNRSTYLLAGAIIVGVVTLVFEVFRTVHGIHTYHKSKWLKLLQNHAPDADLPSETHTPVQKFMDWFEVHVHSPSRSGSGSARPPRGPSKLSTSSGLGASNNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Z8</accession>
    <name>A0A8T0H0Z8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G077700</name>
        <name evidence="3" type="ORF">KC19_8G078000</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0Z8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274468" evidence="1">
        <location>
            <begin position="25"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0564037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5657" checksum="FA8173E62A7CA39F" modified="2022-10-12" version="1">MQRLCMHNVAILFKCSCTLHRLAADCVEDNMGTIPLNLLPSTHSIQCTIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H675</accession>
    <name>A0A8T0H675_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G137200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H675"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13846">
        <property type="entry name" value="CuRO_1_AAO_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13872">
        <property type="entry name" value="CuRO_2_AAO_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000012">
        <property type="entry name" value="Monocopper oxidase-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034273">
        <property type="entry name" value="CuRO_1_AAO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034271">
        <property type="entry name" value="CuRO_2_AO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="MULTI-COPPER OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709:SF90">
        <property type="entry name" value="OS07G0510900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="42"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="3">
        <location>
            <begin position="168"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="387"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0567471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="552" mass="61469" checksum="E2A9C609FD1BA651" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7I9</accession>
    <name>A0A8T0H7I9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G079600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7I9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004159">
        <property type="entry name" value="Put_SAM_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108:SF1077">
        <property type="entry name" value="METHYLTRANSFERASE PMT27-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03141">
        <property type="entry name" value="Methyltransf_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="108"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="691" mass="77936" checksum="C25B0CCC899A8968" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8G6</accession>
    <name>A0A8T0H8G6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G069400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8G6"/>
    <dbReference type="OrthoDB" id="1908962at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06090">
        <property type="entry name" value="KOW_RPL27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.770:FF:000001">
        <property type="entry name" value="60S ribosomal protein L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001141">
        <property type="entry name" value="Ribosomal_eL27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018262">
        <property type="entry name" value="Ribosomal_eL27_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041991">
        <property type="entry name" value="Ribosomal_eL27_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038655">
        <property type="entry name" value="Ribosomal_eL27_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10497">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01777">
        <property type="entry name" value="Ribosomal_L27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01107">
        <property type="entry name" value="RIBOSOMAL_L27E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="15515" checksum="6BA886390E0DC1A2" modified="2022-10-12" version="1">MVKFLKPNKVVVLLQGRYAGRKAVIVKNFDDGTKERPYGHAIVTGIAKYPRKVIKKASQKTIAKRSRLKAFTKVVNYNHIMPTRYTLDVDLKNTVTAEKLESTASRVEARKAAKAVLEERFKTGKNRWFFSKLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8J1</accession>
    <name>A0A8T0H8J1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G112300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8J1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="13193" checksum="8412BA2FD63FC041" modified="2022-10-12" version="1">MRNDSFNSTSRQSLPDEPSSKCSQSVRTPKRINPEPEQRFQSRKLHTQTNPQSLKCGIFTGARKLQKRAKMGILFPKTGSTDDCTQISWRTIELPTNGTRARTMASKKLRREIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9R3</accession>
    <name>A0A8T0H9R3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Origin recognition complex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_7G017300</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle and development dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Binds unmodified and methylated histone H3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ORC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9R3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005664">
        <property type="term" value="C:nuclear origin of replication recognition complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033314">
        <property type="term" value="P:mitotic DNA replication checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000691">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000199">
        <property type="entry name" value="Origin recognition complex subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041083">
        <property type="entry name" value="AAA_lid_10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017956">
        <property type="entry name" value="AT_hook_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050311">
        <property type="entry name" value="ORC1/CDC6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763">
        <property type="entry name" value="CELL DIVISION CONTROL PROTEIN 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10763:SF23">
        <property type="entry name" value="ORIGIN RECOGNITION COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17872">
        <property type="entry name" value="AAA_lid_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="WHD_Cdc6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00929">
        <property type="entry name" value="ATHOOK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00384">
        <property type="entry name" value="AT_hook"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="15">
        <location>
            <begin position="227"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="BAH" evidence="16">
        <location>
            <begin position="274"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="69"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="407"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="754"/>
            <end position="784"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="149"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="159"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="407"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="418"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="430"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="754"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="775"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0565832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="913" mass="102422" checksum="6F796A9D1AA1BD9B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC10</accession>
    <name>A0A8T0HC10_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G020800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36759">
        <property type="entry name" value="DYNEIN BETA CHAIN, CILIARY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36759:SF1">
        <property type="entry name" value="DYNEIN BETA CHAIN, CILIARY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="216" mass="22876" checksum="82E9D3185C675614" modified="2022-10-12" version="1">MGQALQKLRGGGAGGGGAALRAAAPPRQHASHNIESARPSPSPSPSSSPSSSPLSAPSPQTVRQSVEVKPQAPEPQRIIEPELIKGEWDRGDPKYSMMVQQVVGKISTRPGGNQEMGNAHVTAEFRRPKPANRHTSAATGPDEEHVVATGTLNLAGIQEALRLYQGLGEGQEKPLDVKTLAAKFNVDAVLLEKVLLYTSLPIPSQESQNPPQKLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCG2</accession>
    <name>A0A8T0HCG2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">microtubule-severing ATPase</fullName>
            <ecNumber evidence="7">5.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G096100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers.</text>
            <dbReference type="EC" id="5.6.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.1" evidence="7"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCG2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008568">
        <property type="term" value="F:microtubule severing ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000066">
        <property type="entry name" value="AAA-type ATPase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.80:FF:000019">
        <property type="entry name" value="AAA-type ATPase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000958">
        <property type="entry name" value="Spastin, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.80">
        <property type="entry name" value="Phosphotransferase system, lactose/cellobiose-type IIA subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050304">
        <property type="entry name" value="MT-severing_AAA_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Spast_Vps4_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074">
        <property type="entry name" value="AAA DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23074:SF86">
        <property type="entry name" value="SPASTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="11">
        <location>
            <begin position="67"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="10">
        <location>
            <begin position="264"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="19"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="148"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00036378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="503" mass="54250" checksum="5A0195DF8DBC3CA3" modified="2022-10-12" version="1">MWKLVESLQAAVLGPKAEGEGGAGAGAGGGGGGGGGDEAMESSRGNQPAAASLVLGNVDGERVVGKLRGYFNLGKSEIDKAVRADEWGILEDALLHYRNADRILTEGVALPAMVESSRLADEVKQWKQKMAKWKGQVAERLQILERRARGESIDTSPGPAPVESRPAAARSHSVPLSQPERKISRRPQSAAPNSRNAGLTTPRSVAVPGVDSKLVELIENEIVDRTPSVKWDDIAGLAKAKQALLEMVILPSVRSDIFQGLRKPAKGLLLYGPPGNGKTMLAKAVASESAATFFSISASSLTSKWVGEGEKLVKALFAVAGARQPSVIFIDEIDSIMSARSANENEASRRLKTEFLVQFDGVMSDGNDRVIVMGATNRPEELDSAVRRRLVKRIYVPLPDAEARRALLKNLLKGDDYALQGSDLERLVRETDGYSGSDLKALCQEAAMLPIRELGGLVSTIKKNELRPLRFSDFKAAMKEIRPSVSRSQLQSFEQWNQEFGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD48</accession>
    <name>A0A8T0HD48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-polyphosphate phosphotransferase</fullName>
            <ecNumber evidence="1">2.7.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G004900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09165">
        <property type="entry name" value="PLDc_PaPPK1_C1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09168">
        <property type="entry name" value="PLDc_PaPPK1_C2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.870.10">
        <property type="entry name" value="Endonuclease Chain A"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="entry name" value="Polyphosphate kinase middle domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.310">
        <property type="entry name" value="Polyphosphate kinase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003917">
        <property type="entry name" value="PRK05443.1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003918">
        <property type="entry name" value="PRK05443.1-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003921">
        <property type="entry name" value="PRK05443.2-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218:SF0">
        <property type="entry name" value="POLYPHOSPHATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56024">
        <property type="entry name" value="Phospholipase D/nuclease"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143724">
        <property type="entry name" value="PHP14-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="PPK N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polyphosphate kinase N-terminal" evidence="9">
        <location>
            <begin position="235"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Polyphosphate kinase middle" evidence="8">
        <location>
            <begin position="353"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="domain" description="Polyphosphate kinase C-terminal" evidence="11">
        <location>
            <begin position="566"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="domain" description="Polyphosphate kinase C-terminal" evidence="10">
        <location>
            <begin position="739"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="165"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0568234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="966" mass="106597" checksum="9F57AB7D1DF90D94" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGJ0</accession>
    <name>A0A8T0HGJ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipase-like C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G103000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGJ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056304">
        <property type="entry name" value="Lip-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34043:SF3">
        <property type="entry name" value="ALPHA_BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24708">
        <property type="entry name" value="Lip_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Lipase-like C-terminal" evidence="7">
        <location>
            <begin position="97"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF24708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0569618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="488" mass="55408" checksum="D37062C0E5F58A7C" modified="2022-10-12" version="1">MGMMCRMFWDMVSYGDVIFSCFVHTFYGCHMMLTAIWMDLMSSSASGPEDRFRASPVIEADESETDNRERSNGVVVTTESDGHNLGYAGSFMAGHEKAPIVLVHGCFGFGEYKMGKISYWGGVEKNDERIFAPDLGAVCSMHDRAFELFYYLKGGTVDYGVERSEKYGHSRFGHTYHQGRYPGWSSKHPIHLVGHSTGAQVCRLFQNMLADKVFPGHEDTSADWVLSITSISGALNGTTRVYTDGIRPEDGWSIKRGFCALQALRVVVILYEWLDIPFLKKYYDLGFDHYNLQWRKAGISGLVKALFNRSGPFVRGNYVVPDLSVHSAVEMNKKLRTFDKTFYFSYATKGTKKWFSLWTLPGTVFGTHYLLFIRSLQIALWRYPKGLPLPYEGFSDDEWEDNDGAVNTKSQLYPCVPCEHPSYDLGTDLSGLKEGQVLQPGIWYYTTLVGDHIIFAITRRRAGVTFDLLYDSVFQRCRKQLRLSPNPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGK1</accession>
    <name>A0A8T0HGK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G190500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16076" checksum="4AC47FCB3BFAE308" modified="2022-10-12" version="1">MPMPMPMPMPEGGPVPVPVTQPGAAAGAGAGHAVALIVWCTMWVVAPLRSALRLFSLSALLFPPSAPTHPSPCNFSPLLRRPRSYFSPPLPPDFLLSPDVLYTHPPHLGGSWSTSIPYQGTTPFFQWETSWKQLLSMPFHVCKVYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHI8</accession>
    <name>A0A8T0HHI8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G150300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHI8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035855728" evidence="1">
        <location>
            <begin position="21"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6877" checksum="88F35EA37E0E957D" modified="2022-10-12" version="1">MPRLFVVFWLLGLGITKLSTLQMENYGKLCLLYCFQDFNSSVSHYILQVLFDFSFIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJ71</accession>
    <name>A0A8T0HJ71_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Epidermal patterning factor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G191200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJ71"/>
    <dbReference type="OrthoDB" id="1937916at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010374">
        <property type="term" value="P:stomatal complex development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039455">
        <property type="entry name" value="EPFL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109:SF4">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17181">
        <property type="entry name" value="EPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035861402" description="Epidermal patterning factor-like protein" evidence="6">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="155" mass="17005" checksum="C486380FE83083F1" modified="2022-10-12" version="1">MSILFRSRMLLLLTMVSFLKAVAGRRIPAAPSIFTASSTPTPQIELPSSAELTAEDEMGFVVVTWKRGRYYQDLSSPPPPNISIFRGNIEPANTIYGHRLLLGSAPPSCQGKCGSCVPCFPIHVSLGGPHAGSITEQEYYPEAWRCKCDNRTFMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK15</accession>
    <name>A0A8T0HK15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G212200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13145" checksum="3D2346FB54079567" modified="2022-10-12" version="1">MNTSAFPAKIIRLADERVTWFSSSFATLKTIIEKHFAISYKIRVISHGYPVTAIAHRTEAHKFELRTTRCNPSLVSSQHNVTAHNPSAVDPMQALPRSDTSSTKLTLSMKNAKHIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK22</accession>
    <name>A0A8T0HK22_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Plectin/eS10 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G214600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK22"/>
    <dbReference type="OrthoDB" id="5211809at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000025">
        <property type="entry name" value="40S ribosomal protein S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005326">
        <property type="entry name" value="Plectin_eS10_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037447">
        <property type="entry name" value="Ribosomal_eS10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12146:SF0">
        <property type="entry name" value="RIBOSOMAL PROTEIN S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03501">
        <property type="entry name" value="S10_plectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Plectin/eS10 N-terminal" evidence="7">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="91"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0571147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="183" mass="19913" checksum="7CCDC2E6F33941A0" modified="2022-10-12" version="1">MLIPKKNRVEVYKYLFKEGVLYAKKDFNAPKHPEIDVPNLQVIKLMQSFKSKEYVKESFAWRHYYWYLTNDGIEHLRTYLNLPSEIVPATLKKSARPPSRPMGGAGGDRPPRGPPREGERPRFGGDREGYRSSGGRGGAPGGIGGEKGGAPGEYRPEFRGGRGGFGRGGGGSFGAGAPGASTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNX1</accession>
    <name>A0A8T0HNX1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG102500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNX1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="165"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="213" mass="24147" checksum="D81D46A5E7BE18CA" modified="2022-10-12" version="1">MADVDCRARASFFMRCLGTRKYVCTQNLRHDFRKLFALAPAQYPCRVLVPQVPAVLSCPEAPLATPRARFRLRQEVTLLAQSNCLCSPRLYYPLLSEPNPQSMPSTSNLLNTGILTVNALVHEPQFSPSLLRCAFYTPILKLHFPPSPRASRTPLKRMSHSLMAAAPHDNGYSDRKEVNCKQFKTKPQPRTQASKDPLRRIRGIFACLRVREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSA2</accession>
    <name>A0A8T0HSA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG218900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="57602" checksum="BDBEA058DA07DB3C" modified="2022-10-12" version="1">MSKNKKQKNVGEWANKFDDMPSLRCKDYIVAFIVEFYQENTLVSLNSRYVRYEEDGPRKFKSEMETKIRDRLMDPCWHSDTQKPGYDHFVSQRAHDALWNAREVITKYAKAQRGGVQAFKDTIAKADCFTRLMAPHSSRKHRRASITWWNSPIGMETAADLRKRHLTILADFAIFYYLDKEVQRGGYATIRRVRIEGNPEIPPYWEFAEKRPLNWSMRPDLARVDHNNESLAIRIPHPGVIRFQAIHQLEHVGFMFWWNGGTLQAMLQRDNEAPGDLPIDYIFRENADDSPILGKRLQLFRSKRTELAWALCNIIDAVHKYGYLHNDLSPDNILLHFPEDESKIYIGVCDWGLMTKTLENRRSPWVFESVHQKEETMRRRYWVDPRVVYVHKENQDIQIIPDLTVASEDFAAAKIAAKINRGNMCTAYHEAELVETRHFQNIGELAMVFEGYIERVCQNNRGTIGGLGHLINRFRDTHNWPTPIEHYREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSH3</accession>
    <name>A0A8T0HSH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">fructokinase</fullName>
            <ecNumber evidence="8">2.7.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_VG202800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37721"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.4" evidence="8"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008865">
        <property type="term" value="F:fructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01167">
        <property type="entry name" value="bac_FRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1190.20:FF:000005">
        <property type="entry name" value="Probable fructokinase-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050306">
        <property type="entry name" value="PfkB_Carbo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43085">
        <property type="entry name" value="HEXOKINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43085:SF1">
        <property type="entry name" value="PSEUDOURIDINE KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="Ribokinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate kinase PfkB" evidence="11">
        <location>
            <begin position="38"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0573709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="382" mass="41853" checksum="4CFD059FBB8EB978" modified="2022-10-12" version="1">MPKPKKRPKRVKGGANEVSMTCSCSGRLFSNPFKGKSELVVCFGELLIDFVPTVGGLSLADAPAFKKAPGGAPANVACGIAKLGGNAAFVGKVGDDEFGYMLCDVLKDNKVETKGIRFDSEARTALAFVTLRDDGEREFMFYRNPSADMLFQIHELDLDILRQSSIMHYGSISLITEPSRSTHLEAMRIAKEAGSLLSYDPNLRLALWPSAAAAKEGIKSIWDQADIIKVSDEEVIFLTGGDPKDDTNNMRMFHPLCKLMLVTEGGEGCRYYTKKFKGHVKGVKVQVVDTTGAGDAFCAGLLSQIAQDPSIMDEEKKLRYALLFANACGAITTTERGAIPSLPDKDTVMRLIKKPNKEAVISTDPSWQGYQRWRYRNSTTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTW1</accession>
    <name>A0A8T0HTW1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG243300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="10006" checksum="F6AB43B8CC3DA507" modified="2022-10-12" version="1">MRPTRLGDAYHIERALATRQEFPDIHVVAKKCHGFKSQFVQTVKTYHRKYGYDSKLTKPLMGTQAVPFVGKELLQNIQGRHTKLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVZ2</accession>
    <name>A0A8T0HVZ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG327600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVZ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15995" checksum="B09E188255402A2F" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKRQSSTPTKRALYNNVVDKPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRRHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQCQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZS1</accession>
    <name>A0A8T0HZS1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G100100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZS1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026205">
        <property type="entry name" value="PIBF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18950:SF0">
        <property type="entry name" value="PROGESTERONE IMMUNOMODULATORY BINDING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18950">
        <property type="entry name" value="PROGESTERONE-INDUCED BLOCKING FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10681" checksum="D9EEF4B4CDC817CA" modified="2022-10-12" version="1">MCNLSRRQSQVEQDVPSLEDQLIALKDALHNFDICEPMYMELKSIPEQRRTAREHILIMAYEKYQYCREEIQELRMSRDTSRSDSCGDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I062</accession>
    <name>A0A8T0I062_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G109000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I062"/>
    <dbReference type="OrthoDB" id="1910373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045273">
        <property type="term" value="C:respiratory chain complex II (succinate dehydrogenase)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025397">
        <property type="entry name" value="SDH5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36139">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE SUBUNIT 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36139:SF1">
        <property type="entry name" value="SUCCINATE DEHYDROGENASE SUBUNIT 5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14290">
        <property type="entry name" value="SDH5_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="198" mass="21527" checksum="714AEB270198F71E" modified="2022-10-12" version="1">MFDFGAGEPVAQRSMIFGGFPAQVRYMSSDLSALPDIKDGGILKALHALLGANWTKVEPSVRDAVEASLKISSDDVVGKEALTDAWRAAEAVEKFGGNMLQELLLEITDLSGGTGEDVKPIPDSTYNAVEAAYKKYIAYLDSFEEDEAYLKKKVENELGGLFLQIKQRLAGMDPKWSKITLLGTSGLSGSYIERRALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1I7</accession>
    <name>A0A8T0I1I7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G147400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="119"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="275" mass="30564" checksum="34AD0C55F22BED36" modified="2022-10-12" version="1">MKQEFEIPSGSPVAIPYKWEAAPGRPIAEAVPVVEPWMSPLRPPPGNRKLSVSQFDSFEPEPPVIDESQLAGKVLMKLNRLRRKSIAAGACFKSEATRVMQQSGRLFALEDLNRCNGDPGTMSRSCSVTSTFDPPNTPRYSTSVDSSFSEPFSMRTTNSSPSAGATPSSPCSTNARPPSYRHHLEDGDPRHDSHELPDDDNKTLPGPSESAWHQPHIDEAEQTSDVPQNRQMRRSYSNFVSTFVRQSSPSHSFKHLMFVRTFRKSKTAKQLDFGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I387</accession>
    <name>A0A8T0I387_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G130900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040:SF13">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040">
        <property type="entry name" value="PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="550"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="613"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="660"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="690"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="747"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1225"/>
            <end position="1246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1258"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1314"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1341"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1371"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1398"/>
            <end position="1417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1451"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="148"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="891"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="786"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="815"/>
            <end position="828"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="838"/>
            <end position="851"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0577103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1482" mass="167674" checksum="1899C88FF4E826B8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3E6</accession>
    <name>A0A8T0I3E6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP deaminase</fullName>
            <ecNumber evidence="3">3.5.4.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G128400</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>AMP + H2O + H(+) = IMP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:14777"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.5.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from AMP: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.6" evidence="3"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3E6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003876">
        <property type="term" value="F:AMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046033">
        <property type="term" value="P:AMP metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01319">
        <property type="entry name" value="AMPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.800.20:FF:000001">
        <property type="entry name" value="AMP deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.140:FF:000035">
        <property type="entry name" value="Probable amp deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.140">
        <property type="entry name" value="Metal-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006650">
        <property type="entry name" value="A/AMP_deam_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006329">
        <property type="entry name" value="AMPD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01429">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11359:SF0">
        <property type="entry name" value="AMP DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19326">
        <property type="entry name" value="AMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="Metallo-dependent hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00485">
        <property type="entry name" value="A_DEAMINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="47"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="12">
        <location>
            <begin position="53"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="159"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="712"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="493"/>
            <end position="498"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="690"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="693"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="767"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="768"/>
            <end position="771"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR606329-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR606329-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR606329-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0577068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="874" mass="99741" checksum="1C176A0B1CA43E18" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4E5</accession>
    <name>A0A8T0I4E5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G018200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4E5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="225"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="416"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="440"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="558" mass="60739" checksum="CB80CF05183128A2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5Z6</accession>
    <name>A0A8T0I5Z6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Roadblock/LAMTOR2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G022100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GAMAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5Z6"/>
    <dbReference type="OrthoDB" id="9985637at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.30">
        <property type="entry name" value="Dynein light chain 2a, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10779">
        <property type="entry name" value="DYNEIN LIGHT CHAIN ROADBLOCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103196">
        <property type="entry name" value="Roadblock/LC7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Roadblock/LAMTOR2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="97"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="112"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0578429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14592" checksum="0510950D32661277" modified="2022-10-12" version="1">MGEVETALKRILDLEDVIGLLLIDQDGSVLRNTLPEEHAKKYVMEIPSLTIMCRSAAREIEPKDELQMLRIKSRKHEMIVVVDDKFTLLLLQEYPGFWIEPPPPPPTPPRDSDDEFFDDDEDEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6P8</accession>
    <name>A0A8T0I6P8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein TIC 22, chloroplastic</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Translocon at the inner envelope membrane of chloroplasts 22</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_4G075900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in protein precursor import into chloroplasts. Imported into the intermembrane space via the Toc translocon. May be involved in the import pathway used by proteins without a cleavable N-terminal pre-sequence.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast intermembrane space</location>
            <topology evidence="8">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the Tic22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6P8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031972">
        <property type="term" value="C:chloroplast intermembrane space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1350.100:FF:000001">
        <property type="entry name" value="Protein TIC 22, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007378">
        <property type="entry name" value="Tic22-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33926:SF4">
        <property type="entry name" value="PROTEIN TIC 22, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04278">
        <property type="entry name" value="Tic22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="6 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00053802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00061192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00072390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00082221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0579142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="362" mass="40407" checksum="CAFDF5D830F17585" modified="2022-10-12" version="1">MMDDASGRRNGVQRWSGALVSDLQRRVAGAHNWLGVAVQEGGSAVARLGQVVEERRVMAVERVEAIGRRRGESAEVDLEKKKLWMRLSGFAAQVQPAVEAVVRMARSQGAAPRPLLAALSLGLPVRGEGVEGKHVFDIAMSAEQVSKRLDGVPVYTVSNSSNEFVLVSDLNTSKSLGIFCFREADAEALLSQVRDREPSLGRGAKVVAVSLDKVYQLSTEGIAFRFLPDPRQVRNALETRSRAGESGKAFDGVPVFQSDNLILRSNNRRFCPIFFSKEDLENALQRAFKQQQRVNPSLKVNTDIQVGSFEDVLKRMEVWLFLLFIFTVVCTNFGSPIIKICRRMDLCRQWKLYRSVLVLFYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6Y9</accession>
    <name>A0A8T0I6Y9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G025600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6Y9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030619">
        <property type="term" value="F:U1 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030620">
        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000387">
        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024822">
        <property type="entry name" value="Coilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197:SF0">
        <property type="entry name" value="COILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197">
        <property type="entry name" value="COILIN P80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="174"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="181"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="235"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="261"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="622" mass="70774" checksum="CE25E1F9424AADE1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7I7</accession>
    <name>A0A8T0I7I7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G103100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006120">
        <property type="term" value="P:mitochondrial electron transport, NADH to ubiquinone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032981">
        <property type="term" value="P:mitochondrial respiratory chain complex I assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849:SF20">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54862">
        <property type="entry name" value="4Fe-4S ferredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12145" checksum="A4060C6B8DAE8654" modified="2022-10-12" version="1">MKKPTARKPPAFLDLAYLAPALCLCMWLTSFHQIKYPFEKGPLSPRFRGEHALRRYPIGEERCIACKLCEAVSHLLALEKLQVLCSCFHMVKQCPITVHLQWNFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8W9</accession>
    <name>A0A8T0I8W9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_4G059100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8W9"/>
    <dbReference type="OrthoDB" id="10253408at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000323">
        <property type="term" value="C:lytic vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000057">
        <property type="entry name" value="Cysteine protease RD19A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025661">
        <property type="entry name" value="Pept_asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025660">
        <property type="entry name" value="Pept_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013128">
        <property type="entry name" value="Peptidase_C1A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013201">
        <property type="entry name" value="Prot_inhib_I29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12411">
        <property type="entry name" value="CYSTEINE PROTEASE FAMILY C1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08246">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00705">
        <property type="entry name" value="PAPAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00848">
        <property type="entry name" value="Inhibitor_I29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00640">
        <property type="entry name" value="THIOL_PROTEASE_ASN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00639">
        <property type="entry name" value="THIOL_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035893271" evidence="9">
        <location>
            <begin position="23"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Cathepsin propeptide inhibitor" evidence="11">
        <location>
            <begin position="58"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C1A papain C-terminal" evidence="10">
        <location>
            <begin position="141"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0578908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="371" mass="39896" checksum="AB60CBD5F6F99FDA" modified="2022-10-12" version="1">MAGRGMLLLALLVLGCVGFAAATPIGDGIRQVIDHEGGLGDGTVGQWAHALCGAEKKFEGFMREFGKVYHTVEEYEHRFGVFKDNLLKALKHQALDPTASHGVTQFSDLTEEEFANQYLGLKVPQALKSEPSAPNLPTGDLPANFDWREKGAVSAVKNQGACGSCWAFSTTGAVEGAHFLATGKLLSLSEQQLVDCDHQCDPEERDACDSGCNGGLMTNAYKYVEEAGGLELESDYPYTGRDGKCGFNTNKVAAKVSNFTNIPIDEDQVAAYLVKSGPLAIGINAEFMQTYIGGVSCPLLCNKRNLDHGVLLVGYGERGFAPARLSYKPYWIIKNSWGPMWGEKGYYKICRGHGECGLNTMVSAVAAGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9Z6</accession>
    <name>A0A8T0I9Z6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G109000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9Z6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37716">
        <property type="entry name" value="OS07G0568900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37716:SF1">
        <property type="entry name" value="OS07G0568900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="24275" checksum="3D32F4E7EA74A533" modified="2022-10-12" version="1">MATIVVTPCLADANAGALCHHRPSLQQLRGPQQMRNCAIPLRSGLFGLSRKVVRGSEFTRRSLQGGPRADSETEGNPSRAEGNGRLSGLDELDNQLRSLSSSDNLVSDAKPTSNGNVETPPTREERKRVDWPVFGEGFVLFVSGGLILLTILNNILFKLFLGPPVPRIPLEGLEIPRLGTELPEQPPSDSPRPQRYKLRSYNDPKYLQQFAPSPKTDKPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID97</accession>
    <name>A0A8T0ID97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G002400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="15770" checksum="E388FBA4D4251966" modified="2022-10-12" version="1">MSADISGQNRSMKTLRLLSAWSLRIGCFSFSIFSKPLAVLSTGGLRFAVGLREASVDELSSFFLFFLSFPFPTSMGVYLVPEVAISPDFVHRISSSTQPQIRKFLFTGKSPGVSHLLDFDKSSNTGGIVTSLIQHMQAFPRNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDA8</accession>
    <name>A0A8T0IDA8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G208700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDA8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035797786" evidence="1">
        <location>
            <begin position="21"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6076" checksum="FC3DB2B40635277F" modified="2022-10-12" version="1">MHKDISFRFVLVGIVTYALWESWCSGCRNTAHTFRIGKKGENGRQAPEHGRAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGC8</accession>
    <name>A0A8T0IGC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G264200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035845792" evidence="1">
        <location>
            <begin position="18"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6792" checksum="A3577A939E813AD4" modified="2022-10-12" version="1">MFLFILVLSNVSIHSLSKILYMRIQDMNCFASRACDRWWEFRQWFTSGVLRARSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IH32</accession>
    <name>A0A8T0IH32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G105100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IH32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006869">
        <property type="term" value="P:lipid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21669">
        <property type="entry name" value="SMP_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052847">
        <property type="entry name" value="Ext_Synaptotagmin/KAHRP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031468">
        <property type="entry name" value="SMP_LBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47042">
        <property type="entry name" value="C2 DOMAIN-CONTAINING PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47042:SF4">
        <property type="entry name" value="OS02G0313700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51847">
        <property type="entry name" value="SMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="4" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="SMP-LTD" evidence="9">
        <location>
            <begin position="81"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="8">
        <location>
            <begin position="284"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="430"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="516"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="559"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="637"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="438"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="534"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="637"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="720"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="837" mass="93708" checksum="15DA9B07A72962E8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II89</accession>
    <name>A0A8T0II89_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L18a-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G080700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II89"/>
    <dbReference type="OrthoDB" id="1922941at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46666">
        <property type="entry name" value="60S RIBOSOMAL L18A-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46666:SF2">
        <property type="entry name" value="60S RIBOSOMAL L18A-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16002" checksum="195F02B4684BE0EF" modified="2022-10-12" version="1">MKNGCRCKREDRQVMGEVRDRFRSWRRTMGPYQMLLHPGEYGNMGAEAQPYVGLYDRPLPCCGCGVGWCCFLMGFILPLFWYYGTFLFLGQCQNDPRERPGLAASAIAALVNTVALILALIALFVQHQGFFQSSSTPQAADY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK06</accession>
    <name>A0A8T0IK06_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G092000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK06"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12584" checksum="977EA231AF41C0BC" modified="2022-10-12" version="1">MATSGRAWEQQDRDCCARQNHTPKGASRARDQIAEQTRSTAAARSAIDHHRAVHVCLQAVVRRSDANIYAAYILYIACLRREERSAQHDVRRRRQDCVEHVKRPDIYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK78</accession>
    <name>A0A8T0IK78_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G125000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11445" checksum="9FF375CB9223F20D" modified="2022-10-12" version="1">MFELVHLLRQSFLKLHLKETFYCTMKGALNPLHGHCHIVNALENAEKEMVVSGCVTHLSSIILKKGECRIPCVSLIGKVFYMEYSRMLCFRHLHLRMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKL4</accession>
    <name>A0A8T0IKL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nuclear pore complex protein NUP160 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G099700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005643">
        <property type="term" value="C:nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059141">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021717">
        <property type="entry name" value="Nucleoporin_Nup160"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035192">
        <property type="entry name" value="NUP160_hel_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056536">
        <property type="entry name" value="TPR_NUP160_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056535">
        <property type="entry name" value="TPR_NUP160_M"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21286:SF0">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11715">
        <property type="entry name" value="Beta-prop_Nup120_160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17238">
        <property type="entry name" value="NUP160_helical_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23354">
        <property type="entry name" value="TPR_NUP160_120_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23347">
        <property type="entry name" value="TPR_Nup160_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Nucleoporin Nup120/160 beta-propeller" evidence="5">
        <location>
            <begin position="50"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 helical" evidence="6">
        <location>
            <begin position="531"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 middle TPR" evidence="8">
        <location>
            <begin position="908"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="domain" description="NUP160 C-terminal TPR" evidence="7">
        <location>
            <begin position="1324"/>
            <end position="1482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1156"/>
            <end position="1184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1302"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1307"/>
            <end position="1317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1486" mass="164487" checksum="8E08C9AE22AF5ABC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP44</accession>
    <name>A0A8T0IP44_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G018800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21504">
        <property type="entry name" value="PPP2R3A_B-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.220:FF:000003">
        <property type="entry name" value="Phosphoprotein phosphatase 2A regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.230:FF:000002">
        <property type="entry name" value="Serine/threonine protein phosphatase 2A regulatory subunit B''alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000025">
        <property type="entry name" value="serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041534">
        <property type="entry name" value="EF-hand_13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095:SF0">
        <property type="entry name" value="MIP22305P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14095">
        <property type="entry name" value="PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17958">
        <property type="entry name" value="EF-hand_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="416"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="544"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="555"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0585530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="564" mass="64720" checksum="23952E7D1E77E69C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQF6</accession>
    <name>A0A8T0IQF6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G271800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
            <location evidence="1">Telomere</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQF6"/>
    <dbReference type="OrthoDB" id="2186770at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000783">
        <property type="term" value="C:nuclear telomere cap complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098505">
        <property type="term" value="F:G-rich strand telomeric DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010521">
        <property type="term" value="F:telomerase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032210">
        <property type="term" value="P:regulation of telomere maintenance via telomerase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016233">
        <property type="term" value="P:telomere capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04497">
        <property type="entry name" value="hPOT1_OB1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028389">
        <property type="entry name" value="POT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057620">
        <property type="entry name" value="POT1A/B-like_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011564">
        <property type="entry name" value="Telomer_end-bd_POT1/Cdc13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513">
        <property type="entry name" value="PROTECTION OF TELOMERES 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14513:SF0">
        <property type="entry name" value="PROTECTION OF TELOMERES PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25507">
        <property type="entry name" value="OB_POT1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02765">
        <property type="entry name" value="POT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00976">
        <property type="entry name" value="Telo_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0158">Chromosome</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0779">Telomere</keyword>
    <feature type="domain" description="Telomeric single stranded DNA binding POT1/Cdc13" evidence="5">
        <location>
            <begin position="11"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0585267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="55096" checksum="6DEDAE8718AAF0B5" modified="2022-10-12" version="1">MSNREREGYNYATLAEAVKLVGETVHFYGVVAAYEQPKPTRGRDYLCTMTVIDTSYNSPGLRVLFFAPRLDQMPRVKDLGDVIRFHRLQMKTHSDAPQANGNERSRSSFVLFRGCEGDDYVPYQNPSGTSFTMEASDRNIVGLLRTWASSHSIDTLAGTSKYMKQIKDVAVDSYCDVCCKILFVSEQSAENKVIMHVWDGTDASPACLNPSDHSENGDPGQDLWIAKQVAVPVDVMRGFPALGTVLPLVPDGMPENDSRPLLPVAGDWVKLRNIRFRVRKGLYEGVLYPCSKIGILSPSTQTVQNCERAYEERLASEALRLPQWCPQPPQSMLVTGYDHVKLSALREVLTYPEVTYKFRCMVRVMATWPSDVLDFCEPTDGSAAQPIDHPDQGDFVFVVRLTLEDPTARLHAFLYGEDAVEFFGGCPAANLRRQGDTVVVLKRKVDRLLGVSEHGPPNPPWVTCCLKSYYLDKARPRETRRYRVFGTRFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISI1</accession>
    <name>A0A8T0ISI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Serine aminopeptidase S33 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G034100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050228">
        <property type="entry name" value="Carboxylesterase_BioH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194">
        <property type="entry name" value="HYDROLASE ALPHA/BETA FOLD FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43194:SF2">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN LPX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Serine aminopeptidase S33" evidence="1">
        <location>
            <begin position="253"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="458" mass="51047" checksum="FFBCE15375DB2131" modified="2022-10-12" version="1">MATLKVWAPTKGDRWCSLDCGRQESGLRWFRSRVSGSSRVSFSRAQRLTIMAGMAAAKTPLKLEKAHVLTRQQLDKAKHEMDTFVQKIPNHPERRENASPYYLLHKEGEAVYGTVLVFHGFSATTSQMGLLAHYLFESGFNVYQPALSGHYFLNPDKNWPKHDLKKDIKEKLVKKLMSDPELAAYVQNFISISILTPDTAYGAVDRLKALDEPELLAAVFDEEFGAAFNKYYDSEHMKYLHEAEHRMREVAALPGPLFTVGLSMGGATALSLAATHPEKIAKAAVFAPLLKIVNPHNVRFSKLTGPLGAQEKGWYPDMPFLLSCMVVVDAFGHFVRQDKHLDVLAKIPTFIVQTELDDSADHVVGMQIVKELEDRSAADGPPHISTLYAAAEGVPHPMVHPLEASFAGNTNKFWQSLYQETFRFLTEGTVDVDHLHVKSQDPALPQVKALEIPAVTVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IST3</accession>
    <name>A0A8T0IST3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G033500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IST3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="124" mass="14140" checksum="3AFEF8F06B698E4F" modified="2022-10-12" version="1">MQFSRARRACRLEHPRFGYNLGEVSHSWRRISESVTNMGPETTNSSRELDFLLRWLPSLHMSQCRILFSQSLGGHASTVLAAIPTRRTGRSEADSAHFFFLLAPVITAFCHFKYQGQVQASREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IT11</accession>
    <name>A0A8T0IT11_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Agenet domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G122300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IT11"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008395">
        <property type="entry name" value="Agenet-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014002">
        <property type="entry name" value="Agenet_dom_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36805">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36805:SF7">
        <property type="entry name" value="AGENET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05641">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00743">
        <property type="entry name" value="Agenet"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Agenet" evidence="2">
        <location>
            <begin position="120"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="613"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="668"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1087"/>
            <end position="1101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1101" mass="120942" checksum="B9CFD7FA4B8DBB54" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITP9</accession>
    <name>A0A8T0ITP9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G058800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="53"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="209" mass="22764" checksum="93DDE7FE6EB790C3" modified="2022-10-12" version="1">MSTPMTRTQSESTSINITTREFLASQPCIATPSPPLPSSTPHPTRLQSINTIHSSKTPPLPTSTTKTHTHIPTTSCTHTTNSSNTISSPLAQKIPLQHPKPYTKPLHQKSQTPTHSSTKTLTKTQRLAPTPPPLSSFHNTTQATKTSRPKWQLGSELRPANKQSINVPPENLNPCTTALNSHAIDMPSAQLSSNCSDLSCHNYHIFPTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWX5</accession>
    <name>A0A8T0IWX5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G226300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="7964" checksum="0376656AB5E8CA7A" modified="2022-10-12" version="1">MGRNSLKTYGLLRRSEFRNYEGACNAHSLGWNILGLTIALTFFLCVCEHLFSINSVTLLNELRQIGFLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXY8</accession>
    <name>A0A8T0IXY8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G216200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="19207" checksum="CD2C2F8EB7FB0648" modified="2022-10-12" version="1">MRSPRYFASCGAEFTLRRRSQRQVQRVTLAIILDWYAWVGSRSSFTFLAFRQRLATVCMSPSSRPMVSTAVMSVVVGHPAAAMACLHGQHSCERFQPGGSLKLGRREFLGERNFLHARTRVKGRRGGSRIQVRAGLEELSSNQRQQVLSASSLNLLRQPWPVRVSTGSWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYY5</accession>
    <name>A0A8T0IYY5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G202900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="11888" checksum="C03DC19CBB3A63D0" modified="2022-10-12" version="1">MTGTECIPGKVNGVKHCRLLQHSSVSEVSDMECGHGFSSSPGNCAAETPMWALPGRGGLECGRVDVHSWACGRSVEEGRMGYSQMGHCFRTLDSSVTGVGTCKNLFISMRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZW5</accession>
    <name>A0A8T0IZW5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF4378 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G268900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032795">
        <property type="entry name" value="DUF3741-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025486">
        <property type="entry name" value="DUF4378"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21726:SF61">
        <property type="entry name" value="DNAA INITIATOR-ASSOCIATING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21726">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P DOWN SYNDROME CRITICAL REGION PROTEIN 5 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14309">
        <property type="entry name" value="DUF4378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14383">
        <property type="entry name" value="VARLMGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3741" evidence="3">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4378" evidence="2">
        <location>
            <begin position="974"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="308"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="350"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="519"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0588787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1144" mass="126683" checksum="044BF4359CAC7A82" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0G1</accession>
    <name>A0A8T0J0G1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G284100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36813">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36813:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="81"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12145" checksum="043850081CE38730" modified="2022-10-12" version="1">MGGVCAGCFRGQEKEENGKYARYEAPQFAQHPPVQPQQQQPRPQPKQKKTSEEERAQSEEARSNAAIAAQKRLEAFEKSAGGKAAKKAIAAAKAPPPSRDNRDDVAKDWAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0U9</accession>
    <name>A0A8T0J0U9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Arf-GAP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G259000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0U9"/>
    <dbReference type="OrthoDB" id="983479at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08830">
        <property type="entry name" value="ArfGap_ArfGap1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.150:FF:000014">
        <property type="entry name" value="ADP-ribosylation factor GTPase-activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.150">
        <property type="entry name" value="Arf GTPase activating protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044519">
        <property type="entry name" value="ARF_GAP_AGD6/7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001164">
        <property type="entry name" value="ArfGAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038508">
        <property type="entry name" value="ArfGAP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47021">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47021:SF4">
        <property type="entry name" value="ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01412">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00405">
        <property type="entry name" value="REVINTRACTNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00105">
        <property type="entry name" value="ArfGap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="ArfGap/RecO-like zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50115">
        <property type="entry name" value="ARFGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Arf-GAP" evidence="7">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="353"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="241"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="252"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="445"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0588646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="47776" checksum="CB387E78A720828D" modified="2022-10-12" version="1">MASPAAAAKLREMQAQAGNKVCVDCPQRNPQWASVSYGIFMCLECSGKHRGLGVHISFVRSVSMDSWSEIQLKKMQAGGNAPLNSFLAQYGIPKETDIVAKYNSKAAAVYRDRIQALAEGRSWNAPAVVKESVGTGSQGVGRTSSGGGSGGGGARGSNGWDDWDDEPSRGSGGSGNIRRHGSESSISGGGGGGPPRSNSSGDMYTKSQLEQSAAGKESFFARKQMENASRPDNLPPSQGGKYVGFGSGGGRPPQARGPPAGGDVLNESVTVLTQGFSRLSAVAASAAQNAASVLQASTTDIQAKVREGGYDQKVNETVSVVAAKGTEVGQKAWGFMRGVMAMASQQVEAYTKDGMSSSSNQYGSSYGSLDSRGGSVGYQELNGNHAWDAPAKSNDGWQEWEDTKKVAEPKPQTTTTKKETGSWAGWDDHEDDHQSSTPSKKADDGWGDDSWDAGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1I1</accession>
    <name>A0A8T0J1I1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Enhancer of mRNA-decapping protein 4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G021400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">P-body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the WD repeat EDC4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000932">
        <property type="term" value="C:P-body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031087">
        <property type="term" value="P:deadenylation-independent decapping of nuclear-transcribed mRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.220.100:FF:000001">
        <property type="entry name" value="Enhancer of mRNA-decapping protein 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.100">
        <property type="entry name" value="conserved c-terminal region of ge- 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045152">
        <property type="entry name" value="EDC4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049404">
        <property type="entry name" value="EDC4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044938">
        <property type="entry name" value="EDC4_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032401">
        <property type="entry name" value="EDC4_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15598:SF5">
        <property type="entry name" value="ENHANCER OF MRNA-DECAPPING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21289">
        <property type="entry name" value="EDC4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16529">
        <property type="entry name" value="Ge1_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 7" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 WD40 repeat region" evidence="9">
        <location>
            <begin position="273"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="7">
        <location>
            <begin position="438"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Enhancer of mRNA-decapping protein 4 C-terminal" evidence="10">
        <location>
            <begin position="1371"/>
            <end position="1483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="82"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="649"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="744"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="968"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1029"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="110"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="663"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="687"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="815"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="833"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="859"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1038"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF21289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1502" mass="162909" checksum="F0483B0FFC30910B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1S7</accession>
    <name>A0A8T0J1S7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G054900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1S7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="entry name" value="D-amino Acid Aminotransferase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47703:SF2">
        <property type="entry name" value="D-AMINOACID AMINOTRANSFERASE-LIKE PLP-DEPENDENT ENZYMES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="D-aminoacid aminotransferase-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0589870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="320" mass="35502" checksum="7042D3A8A2C47997" modified="2022-10-12" version="1">MAESFAPWAVLSNHGCVHLDSAPASVFLKTSPHGAYTTTRTGNEGEYLLLWTRHLRRLSQSMEVLASAMPDRFPHPPSTFSGLQNLVKPSLQAGLQRALPLRRSGEELNVTILASTDGHSDRLTWDVSVHLSNYVPRSPPIPAHIAVLGSGRDLPLAKYSLWASAREPLEKAKPPGATEIVLSNDGDGLLEGSVTNFFVVAMNPDVEVQTAALGDGVLPGVIRQLVIEVCEEYEIPVREVMPSWQARGTWIESFVTSSLRMVQPVESIRMCQPWVPPQLLEDSEWVEVRFDRIASVTERIRSRVLQRALDEGLPVREYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2G4</accession>
    <name>A0A8T0J2G4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Receptor ligand binding region domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G073000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2G4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051010">
        <property type="entry name" value="BCAA_transport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30483">
        <property type="entry name" value="LEUCINE-SPECIFIC-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30483:SF6">
        <property type="entry name" value="PERIPLASMIC BINDING PROTEIN OF ABC TRANSPORTER FOR NATURAL AMINO ACIDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="Periplasmic binding protein-like I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="465"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="domain" description="Receptor ligand binding region" evidence="6">
        <location>
            <begin position="65"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="526" mass="57444" checksum="CD0973FF3324C703" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3B5</accession>
    <name>A0A8T0J3B5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G065800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3B5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12483" checksum="6E1895268ED8C133" modified="2022-10-12" version="1">MVDSHVSFLFLFWNQSNLNANSWPLSNSASQLSIFPGLRSFIQTRYFDDATALNAVIAVDSRVVFEFNGDSCYLGNFMLARMSFNCHNSNNIVTCLTCGCRPMLHMRHSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3V8</accession>
    <name>A0A8T0J3V8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH OST-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G082600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3V8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:RNA nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08824">
        <property type="entry name" value="LOTUS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd10910">
        <property type="entry name" value="PIN_limkain_b1_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="entry name" value="LOTUS domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024768">
        <property type="entry name" value="Marf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379">
        <property type="entry name" value="LIMKAIN B LKAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14379:SF82">
        <property type="entry name" value="OS08G0230500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="369"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="557"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="632" mass="69563" checksum="B155C8C55D7A6DDB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4T9</accession>
    <name>A0A8T0J4T9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ATP-dependent Clp protease proteolytic subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G136100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4T9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000050">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF46">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT-RELATED PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0590924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="292" mass="31739" checksum="2C4E2F8E6706D612" modified="2022-10-12" version="1">MATSALASSASSRLLPRSSTPTASASTSSTSTSLFSRPRSLSRSPGAPDLTANFFSNVHLAVTARREGSSSSRGKVTMMAPIGTPKVPYRTPGEGGWQWVDIWNVLYRERIIFLGQYIDEEFGNQIVATMLYLDSVDSTKPMYLYINCPGGDITPCMAIYDTMESIKSPVGTLALGYAYNNAGLLLAAGAKGMRTAMPLTRVALMSPAGSARGQADDIINEARELSRVRNYVYEQVSKKTGQPLEKVVKDLNRIKRFSAKEALDYGIIDRVVRPKRIKPDARRQESVGVGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J528</accession>
    <name>A0A8T0J528_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">glucose-6-phosphate 1-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G055100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:16249"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58247"/>
            <dbReference type="EC" id="5.1.3.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glucose-6-phosphate 1-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.15" evidence="3"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J528"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047938">
        <property type="term" value="F:glucose-6-phosphate 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09020">
        <property type="entry name" value="D-hex-6-P-epi_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025532">
        <property type="entry name" value="G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122">
        <property type="entry name" value="APOSPORY-ASSOCIATED PROTEIN C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11122:SF39">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE 1-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="Galactose mutarotase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="361" mass="38725" checksum="99FB1AEF237EBB90" modified="2022-10-12" version="1">MALLKLSSSIASTSASLGVAPAIAHSSARSGGVALSWKHSCSPFHAALSSSPGCSSRALPSGVARASQATGVSAVSAEDLNEKFGAKGVKVQSGEGGLTKVVLSTPAGSEAEVYLYGGCVTSWKTSEGKDLLFVRPDAVFTGQKPISGGLPHCFPQFGPGPIQQHGFARNVSWEIASSQSDDETTTLVLQLKPSDYSRNMWDYEFLVTFKIVLGGEKLTTELVVENIDSKPFSFTTALHSYFKADASKTSVTGLKGCKRLDKPYEDPANPIEGQEDRDVIEFPGFVDTMYRETPSELLLDNGFGTKLSIKNEGWTDAVLWNPYLTMEACYKDFVCVENAKLAPVELQPGQSWTAKQFLSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7G3</accession>
    <name>A0A8T0J7G3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">60S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G205700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7G3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002181">
        <property type="term" value="P:cytoplasmic translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd13156">
        <property type="entry name" value="KOW_RPL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.30:FF:000014">
        <property type="entry name" value="60S ribosomal protein L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000915">
        <property type="entry name" value="60S_ribosomal_eL6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_uL2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049633">
        <property type="entry name" value="Ribosomal_eL6_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041997">
        <property type="entry name" value="Ribosomal_eL6_KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005568">
        <property type="entry name" value="Ribosomal_uL6_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10715:SF0">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN EL6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01159">
        <property type="entry name" value="Ribosomal_L6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03868">
        <property type="entry name" value="Ribosomal_L6e_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="Translation proteins SH3-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01170">
        <property type="entry name" value="RIBOSOMAL_L6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL6 N-terminal" evidence="6">
        <location>
            <begin position="8"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0591834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="230" mass="25331" checksum="3AF033E1CE59E22F" modified="2022-10-12" version="1">MVKPAGASKSKELVRGIGRNGRSKTYHKRGLWAIKAKNGGTFPTHQKAAVAEAPAVRAPKFYPADDVAKPLHKNKVINPPKLRTSITPGTVLILLAGHFKGKRVVFLKQLESGLLLVTGPFKVNGVPLRRVNQAYVIATSTKVDISSVDVAKYADAYFKRAVTKTKKGESEFFEAEKEKEEKSIPEEKKEDQKAIDGKLIPLIEAVPELKTYLSSRFSLKSGVKPHELVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J903</accession>
    <name>A0A8T0J903_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase 2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G247200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J903"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050834">
        <property type="entry name" value="Glycosyltransf_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43685">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43685:SF2">
        <property type="entry name" value="GLYCOSYLTRANSFERASE 2-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase 2-like" evidence="2">
        <location>
            <begin position="132"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="397" mass="44458" checksum="5FBEB1035E85141B" modified="2022-10-12" version="1">MTGTVEFQNLCISIAYEVKTVMRDSTLSFFQKLIFCFLKIVCVTGFAIGREYPEQRTRAPTLPPPIPTFTTTERQEVAPLPTTESAGEKEKPAAEESTPETRTDFQELTAESADVELSEFKPTVAIVAPIFVRTLQQRKEVLELISSLDNQTYKAAQIILVDDCSPFPWYLSSATGQSEENLVKLPANTRLVRRPKNHGPAAARSLGLGLAMAEHQAQIVNFIDSDCEADSHWVEAMVTAHYYELKKKSEGSDGAILSGLTHAYGNTHVDKFHDHFGTLNGRIKINGEGLLYAPSCNISIRISQKLISQVGGFDESFPKAAFEDVDYCMRASQCGFLTQCVQNAKIWHKYQTTIPQLFRMFKRYGASEWAVLERHPFYFEMYGASYHIPSQAPKVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9R1</accession>
    <name>A0A8T0J9R1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G207200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14133">
        <property type="entry name" value="PKc_DYRK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000216">
        <property type="entry name" value="Putative serine/threonine-protein kinase dyrk2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000380">
        <property type="entry name" value="Serine/threonine-protein kinase ppk15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050494">
        <property type="entry name" value="Ser_Thr_dual-spec_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058">
        <property type="entry name" value="DUAL SPECIFICITY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24058:SF124">
        <property type="entry name" value="PROTEIN KINASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1078"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="128"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="246"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="465"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="593"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="712"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="860"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="929"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="138"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="593"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="619"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="718"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="767"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="797"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="808"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="876"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="969"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1008"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1389" mass="153526" checksum="EC8B2BD3AA393C09" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAF1</accession>
    <name>A0A8T0JAF1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G256000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAF1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12181" checksum="5C9FC26CD1485EC1" modified="2022-10-12" version="1">MAHYHFFSWPNSHLFSRTDIPLLKPRTAQKLSTTSSSSPAPHLHATPNALSHRLPRLTPLRTQTKIIFSTLQPTIRKLQCNKSAGQVLHTESQSPTNPSHKISREGIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC10</accession>
    <name>A0A8T0JC10_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Tubulin alpha chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G330700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 10">Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02186">
        <property type="entry name" value="alpha_tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1330.20:FF:000001">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1440:FF:000004">
        <property type="entry name" value="Tubulin alpha chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.600">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="entry name" value="Tubulin/FtsZ, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002452">
        <property type="entry name" value="Alpha_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023123">
        <property type="entry name" value="Tubulin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03953">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01162">
        <property type="entry name" value="ALPHATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 10" id="KW-0493">Microtubule</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="11">
        <location>
            <begin position="50"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin/FtsZ 2-layer sandwich" evidence="12">
        <location>
            <begin position="249"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00034296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0593450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="443" mass="48791" checksum="9714D012EAD6C914" modified="2022-10-12" version="1">MRECISLHIGQAGIQVGNACWELYCLEHGIQADGNMPCNRGCTPGSDEAFMTFFSETHAKKYVPRCVFLDLEPTVVDEVRTGTYRQLFHPDQLISGKEDAANNFARGHYTVGKEIVDLCLDKIRKLADNCTGLQGFLVFHAVGGGTGSGLGSLLLERLSVDYGKKSKLSMCIYPSPQVSGAVVEPYNSVLSTHSLLEHTDVAVMLDNEAIYDICRRCLDIERPSYTNLNRLITQVVSSLTVSLRFDGALNVDLTEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQMTVPELTNSVFEPMSMMAKCDPRHGKYMACCLMYRGDVVPKDVNGAIGTIKTKRTIQFVDWCPTGFKCGINYQPPTMVPGGDLAKVQRSVCMISNTTSVAEVFSRLDHKFDLMYSKRAFVHWYVGEGMEEGGVFGGQGGFGCAGEGLRGGGRGLGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G531</accession>
    <name>A0A8T0G531_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G020400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G531"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14986" checksum="A0298335863879C3" modified="2022-10-12" version="1">MVISDGADVQVTTYRTWISRANQKYHAVFIITVAQDCSAFIPNTHTDTQTANTSKILAHTRCPHLSAKLPRQRGERERETATVMSSAHIVTASVSRFHVSTLLTHLVQLFGAVGGSLHGFLQRDIYHETGAWLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G630</accession>
    <name>A0A8T0G630_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G001100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G630"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018790">
        <property type="entry name" value="DUF2358"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123">
        <property type="entry name" value="OS04G0578200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34123:SF4">
        <property type="entry name" value="PHOSPHORIBOSYLTRANSFERASE-LIKE PROTEIN, PUTATIVE (DUF2358)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10184">
        <property type="entry name" value="DUF2358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="NTF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0553308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="281" mass="32089" checksum="B60088ACD3ECB686" modified="2022-10-12" version="1">MASLRLLPMPMLSDYSFGFSSRELSPSTYHVYCNLYCSRIRLQTGMQLGVGLRCGASWGGLLRRTRVEHGVVRMMSLGDNDVVVEEAKQDDEEPEPLLLRMGVSLVTEILRLFSNFGSSQSATATLEVEPSPAVVEDQNVLGALREDYERAYFLTGDFTGTLYADNCLFADPTIQFRGRDKYQRNLKLLVPFFEDPKLTLFDIQEEDLKFGQERSINAKWNLRTYLRLPWKPLIDVDGSTLYVIDANSKIVKHIESWSISGREAVQQLFVPSDRAFFRKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6C9</accession>
    <name>A0A8T0G6C9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G055500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6C9"/>
    <dbReference type="OrthoDB" id="416496at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043527">
        <property type="term" value="C:tRNA methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11715">
        <property type="entry name" value="THUMP_AdoMetMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2130.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RlmKL-like_Mtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054170">
        <property type="entry name" value="RlmL_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47313:SF1">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22020">
        <property type="entry name" value="RlmL_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RlmL ferredoxin-like" evidence="5">
        <location>
            <begin position="110"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal RNA large subunit methyltransferase K/L-like methyltransferase" evidence="4">
        <location>
            <begin position="327"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF22020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0554004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="605" mass="67582" checksum="18674625D03DDEAB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7E8</accession>
    <name>A0A8T0G7E8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G132400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7E8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035835504" evidence="1">
        <location>
            <begin position="21"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6049" checksum="A0B5C084789C807E" modified="2022-10-12" version="1">MNMPRHLATLSLSLIAAAQAIARDKSRLSFKNVRPQPAPGCSILMLHLASKTNLGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9K7</accession>
    <name>A0A8T0G9K7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_11G002400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9K7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="21"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0555781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="262" mass="29229" checksum="716F6DD99AD6D7B8" modified="2022-10-12" version="1">MAMAVAMARTGVVGCRAAHTQLYEVLKVDKSATPAQLKTAYRNLAKDYHPDVSSHPDAQARFVELSSAYEVLIDPEMRAVYDETGERGINSREGKRRGAAQEVWESWAEFKPFKRKTRKGDARSSAAARSGSDYTPENGESVWGSEAQNGDIVEYPLSDAIKAQHQDDRLRGVGLVVSRNIDRGDKDKLSLENLALVEIEPLYREPDSNVWRADPMEGAAFASLPDLRILRTEFNRVTDEWVILDELSHGCDSPSYAEEIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAP1</accession>
    <name>A0A8T0GAP1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha</fullName>
            <ecNumber evidence="4">2.5.1.58</ecNumber>
            <ecNumber evidence="3">2.5.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">CAAX farnesyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">FTase-alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Ras proteins prenyltransferase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Type I protein geranyl-geranyltransferase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_12G168100</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-cysteinyl-[protein] + (2E,6E)-farnesyl diphosphate = S-(2E,6E)-farnesyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:13345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11535"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:86019"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.58"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>geranylgeranyl diphosphate + L-cysteinyl-[protein] = S-geranylgeranyl-L-cysteinyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21240"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11537"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:86021"/>
            <dbReference type="EC" id="2.5.1.59"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein prenyltransferase subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.58" evidence="4"/>
    <dbReference type="EC" id="2.5.1.59" evidence="3"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAP1"/>
    <dbReference type="OrthoDB" id="272289at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005953">
        <property type="term" value="C:CAAX-protein geranylgeranyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005965">
        <property type="term" value="C:protein farnesyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004662">
        <property type="term" value="F:CAAX-protein geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004660">
        <property type="term" value="F:protein farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.120:FF:000004">
        <property type="entry name" value="Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.120">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002088">
        <property type="entry name" value="Prenyl_trans_a"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11129:SF1">
        <property type="entry name" value="PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01239">
        <property type="entry name" value="PPTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48439">
        <property type="entry name" value="Protein prenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51147">
        <property type="entry name" value="PFTA"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00040965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00041392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00042436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00050225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00050428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00055749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0555424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="37839" checksum="524E30201B35D126" modified="2022-10-12" version="1">MAEGGEGGEVRFDWSDVEPIPQDDGPRPVVPIAYTDEFRELMDLFRAVLAKDERSARALKLTADVIAVNAANYTVWHFRRLVLESLGRDLHEELEYLDAAAEGNHKNYQIWHHRRWVVQKLGKDAVYKELEFTEGALKDDPKNYHAWSHRQWLLQELEDWKWELDYCSKLLEEDSANNSAWNQRFFVVTRCPSLGGLLQMRDSEVSYCIDSIKQVPTNESPWRYLKGLFLDDRAAFVSNSVASEACITELVKDPNNVPAFGFLLDLLSAGFQPTSGQKEMLQKVLPAWETPSELTDAVCMRLQKVDAMRCQYWAWRRSLLPLTVAAPEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAW2</accession>
    <name>A0A8T0GAW2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G090400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAW2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8370" checksum="D69E40FB40F9A458" modified="2022-10-12" version="1">MSHRFLYLENLRELGSRLWQQKPRHHRLSSPIPRENPHIMHLACILKPLTVSLDGELNNMDTEKEGLDQID</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCI3</accession>
    <name>A0A8T0GCI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G023000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCI3"/>
    <dbReference type="OrthoDB" id="5407653at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="71"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0556064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="205" mass="24083" checksum="B5158036D92EA914" modified="2022-10-12" version="1">MVSLKLQKRLAASVLKCGERKVWLDPNEVNEISMANSRQNIRKLVKDGFVIRKPQKIHSRARARRALEAKRKGRHSGYGKRRGTREARLPTKVLWLRRMRVLRRLLRKYRDAKKIDKHMYHDMYMKVKGNVFKNKRVLMESIHKSKAEKAREKTLSDQFEARRAKNKATRERKIARREERQAQGIPDVAPAQAPVSDAPVKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCR3</accession>
    <name>A0A8T0GCR3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G006200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCR3"/>
    <dbReference type="OrthoDB" id="1924375at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="248" mass="27502" checksum="DA914CA347142F25" modified="2022-10-12" version="1">MGSWVQGTGTLGHGQSNIYGIHPTALPVVSIQSTNPEAWLQVVQQAMQQTSGVFVISDLQKEMDWREACILSDMLLKSYMSATQHNPLELHPGVDLEKGEGFSTSELAIQKLKFFHPHRDRGLFNVVLGSRSAFRALFIQFGANNRVFGVIPSVPSVYELTAGWDDDALLAVVIPGYSLHLFEPRVPSLTHWVHHTDNTDRVTQVFRCRLRPDFVVAGTQIGLAIQSIEHSPEASRRGSLAASQVRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCS6</accession>
    <name>A0A8T0GCS6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MBD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G096300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCS6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.890.10">
        <property type="entry name" value="Methyl-cpg-binding Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001739">
        <property type="entry name" value="Methyl_CpG_DNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396">
        <property type="entry name" value="METHYL-CPG BINDING PROTEIN, MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12396:SF46">
        <property type="entry name" value="METHYL-CPG-BINDING DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50982">
        <property type="entry name" value="MBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="MBD" evidence="7">
        <location>
            <begin position="637"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="422"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="831"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="861"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="907"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0557021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1169" mass="127558" checksum="F4299202D00DB1CA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCV3</accession>
    <name>A0A8T0GCV3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cilia- and flagella-associated protein 157</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_11G086400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CFAP157 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCV3"/>
    <dbReference type="OrthoDB" id="1901059at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038844">
        <property type="entry name" value="CFAP157"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31954">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31954:SF1">
        <property type="entry name" value="CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="7"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0556883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="245" mass="27943" checksum="02DD1639C85F92B3" modified="2022-10-12" version="1">MTLWKENERLIEENHEQTRQITLLKEVQVQLEQKVYMYQKTLRILVHKLREKENQLEGTKAKILSQMTPEEREDEEDFQELLIRAERLKNAKNAPTPKRIAGKGKGTVPDQKLTQESAIEFLYACLEDMELNSFTKLAAGDAETSEVPSDVPLDQLNLQQRHALLQSLLKRATAVRVITQSLANAAPNKNPPRHQPYTPVISRSNQGGNLVFDVQEVLDLPVKDIMADEDGDRSHDRDNSLLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHK1</accession>
    <name>A0A8T0GHK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G113500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHK1"/>
    <dbReference type="OrthoDB" id="16284at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.140">
        <property type="entry name" value="Cytochrome c oxidase, subunit VIb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048282">
        <property type="entry name" value="COA6_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048280">
        <property type="entry name" value="COX6B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036549">
        <property type="entry name" value="CX6/COA6-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47445">
        <property type="entry name" value="OS08G0441400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47445:SF1">
        <property type="entry name" value="OS08G0441400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02297">
        <property type="entry name" value="COX6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47694">
        <property type="entry name" value="Cytochrome c oxidase subunit h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="116" mass="12712" checksum="0ECD64ACF4D76E04" modified="2022-10-12" version="1">MAGANSATENQPHVEKDVLAAGRASCYKARDAFFNCVEADSGHTTPTEVASVGLLYPSQCKPARAFFEENCRSTWVKHFDRQYSAKKRVKRLLDAGDQNRGPITLPSNKVGLQPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIX5</accession>
    <name>A0A8T0GIX5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein MIZU-KUSSEI 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G150200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIX5"/>
    <dbReference type="OrthoDB" id="1859415at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010274">
        <property type="term" value="P:hydrotropism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006460">
        <property type="entry name" value="MIZ1-like_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01570">
        <property type="entry name" value="A_thal_3588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31696">
        <property type="entry name" value="PROTEIN MIZU-KUSSEI 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31696:SF71">
        <property type="entry name" value="PROTEIN MIZU-KUSSEI 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04759">
        <property type="entry name" value="DUF617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="24879" checksum="CEFC99406F0F4D70" modified="2022-10-12" version="1">MGKSFVDSRKVTSSVNGKSMLVPSEKRIPKPKKVSSLLRAFFHLLPHPLFSCRGSEPSLDNHPQPGNCVIGTLYGQRKGHVFLAIQDDPKCFPLFILELATPTSSLVKEMASGLVRIALECEKSPGEGKLLLQESTWSMFCNGRKTGYATRRDCTEIDRHILTLVQAVSMGAGVLPMANEGFEGELMYMRARFERVIASADSESFYMMNPDGSEGPELSIFLMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKD7</accession>
    <name>A0A8T0GKD7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 17">Peroxidase</fullName>
            <ecNumber evidence="4 17">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_10G011000</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="14 17">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 17">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="14 17">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="17">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="17">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="4 17"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKD7"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000008">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31517:SF84">
        <property type="entry name" value="PEROXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 17" id="KW-0106">Calcium</keyword>
    <keyword evidence="10 16" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 17" id="KW-0349">Heme</keyword>
    <keyword evidence="11 17" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 14 17" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 17" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 17" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 17" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="17" id="KW-0964">Secreted</keyword>
    <keyword evidence="17" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="17">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035966598" description="Peroxidase" evidence="17">
        <location>
            <begin position="32"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="18">
        <location>
            <begin position="33"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="15">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="43"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="76"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="129"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="16">
        <location>
            <begin position="212"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0558188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="36617" checksum="2D0266A68770FC57" modified="2022-10-12" version="1">MGGLRYGRSTTAAVVHIVVATLVLQAQVLLGQDIFVGFYDQSCPQAESIVTQTVKEFNSQDPTTPAALLRLLFHDCFVEGCDASILLDSTPANPNIEKMASPNLTVRGYEVIDKAKERLEAACPQTVSCADIVALAARDGAVLAGLNFQGLPLTMATGRWDGRVSSMDAANSALPSSKSNVQQLTSQFGNKGLSQDEMVTLSGAHTIGKAHCVNFMDRLYDFPGSPNGVDPTLDPAYAAQLQAQCPRGNPNQNTVVDLDQSTPFVMDNNYYSNGFAGKVLFGSDMALFHDFETQFTSNLNVVNGMTWNQKFGNALAQMAAIELKDEFDGEVRLNCRRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLV8</accession>
    <name>A0A8T0GLV8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G114200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLV8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11440">
        <property type="entry name" value="LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="528" mass="60233" checksum="233CEC881C5F4739" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLY8</accession>
    <name>A0A8T0GLY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Puromycin-sensitive aminopeptidase</fullName>
            <ecNumber evidence="10">3.4.11.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Cytosol alanyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_10G001100</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Release of an N-terminal amino acid, preferentially alanine, from a wide range of peptides, amides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.14"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.14" evidence="10"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016285">
        <property type="term" value="F:alanyl aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09600">
        <property type="entry name" value="M1_APN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.390.10:FF:000002">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1730:FF:000005">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1840:FF:000001">
        <property type="entry name" value="Aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.50.10:FF:000002">
        <property type="entry name" value="Puromycin-sensitive aminopeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.2010.30:FF:000002">
        <property type="entry name" value="Putative aminopeptidase N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2010.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="entry name" value="Neutral Protease Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.50.10">
        <property type="entry name" value="Peptidase M1, alanyl aminopeptidase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="entry name" value="tricorn interacting facor f3 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038438">
        <property type="entry name" value="PepN_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012779">
        <property type="entry name" value="Peptidase_M1_pepN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024601">
        <property type="entry name" value="Peptidase_M1_pepN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037144">
        <property type="entry name" value="Peptidase_M1_pepN_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035414">
        <property type="entry name" value="Peptidase_M1_pepN_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02414">
        <property type="entry name" value="pepN_proteo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46322:SF1">
        <property type="entry name" value="PUROMYCIN-SENSITIVE AMINOPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11940">
        <property type="entry name" value="DUF3458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17432">
        <property type="entry name" value="DUF3458_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="Leukotriene A4 hydrolase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Aminopeptidase N-like N-terminal" evidence="16">
        <location>
            <begin position="209"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 membrane alanine aminopeptidase" evidence="13">
        <location>
            <begin position="413"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase Ig-like fold" evidence="14">
        <location>
            <begin position="631"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M1 alanyl aminopeptidase C-terminal" evidence="15">
        <location>
            <begin position="750"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00066316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00081993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF11940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF17432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0558052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1072" mass="117846" checksum="815C3F127F88B694" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMV4</accession>
    <name>A0A8T0GMV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Elongation factor 1-alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_10G114100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01883">
        <property type="entry name" value="EF1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03693">
        <property type="entry name" value="EF1_alpha_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03705">
        <property type="entry name" value="EF1_alpha_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000003">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000005">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000255">
        <property type="entry name" value="Elongation factor 1-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00483">
        <property type="entry name" value="EF-1_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF008969">
        <property type="entry name" value="PRK12317.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="9 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0488">Methylation</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="38"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="480" mass="52964" checksum="06DB8BF76389DCF8" modified="2022-10-12" version="1">MTCSRTPQTPLSPRLRRLPSPSSCFARNSRLFKMGKEKVHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETVKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARFEEITKEVSSYLKKVGYNPDKIPFVPISGFEGDNMIERSSNLDWYKGPTLLEALDAVTEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMLVCFAPTGLTTEVKSVEMHHESMPEAHPGDNVGFNVKNVAVKDLKRGFVASDSKNDPAKEAANFTAQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFAEILTKVDRRSGKELEKEPKFLKNGDAGFVKMIPTKPMTVETFAEYPPLGRFAVRDMRQTVAVGVIKAVEKKDATGAKVTKAAAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN55</accession>
    <name>A0A8T0GN55_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G030100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN55"/>
    <dbReference type="OrthoDB" id="10392851at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="375" mass="44582" checksum="2BB2350B113195EB" modified="2022-10-12" version="1">MPSAASTNDPFAPCEQDPRTPKPPKWDGRKDALPEPQYLPQFKNYQFRYGAYPGYRDCSENPPWPDGAVSEHARRQESPIKYVVGRPGRTTFKPNERVCGDLQFGKPKAKAAHEDMWYRIKDPDYYNLKSKRWDVSGVKRIPPRPFYNREDGHFLLNNTCTIANLCLLPELRRLQCYFFPKLPKIRKDRNFYLPMKKHGRQHTRWRWTETWKRQLIPWYTNYGPEEPEIAQCKEAERLELDKKHTRWHYFMNKESIETLRAWHRRVKVKTPPPKTRPIDYHVKLGRETLNGVRKVKELFEDPILSFWTDPPIDIMEIILFEEAERKRLEEEAKRKNPTPPPPPSICDVCDYYGDRGVIEDKHCSQCTFRTSPTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNZ6</accession>
    <name>A0A8T0GNZ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G050400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNZ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="183" mass="20067" checksum="16080324748388EA" modified="2022-10-12" version="1">MAKGKGFGGMRSSSMDGSYGRINPTKDLYSISELHETEVKSVNFGYERVAKPSIARRSSFSWSRRSSKKHFDIEGLGELDTEPHPSTTSSSKAAAESNHTQAQKKKSKFGIKNFLTGIMDSYKKIMQSAEDSNMHLSDLYPNNSMVAPVTPAAGNRGIKYISPSPGVGRRSLGRVAEEASRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNZ9</accession>
    <name>A0A8T0GNZ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G106500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNZ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="368" mass="41491" checksum="D8446440174A6635" modified="2022-10-12" version="1">MSSLQMGKNMGISTQIVVLVMLLTSTAIITRMVVLSNIDPDSFTSPEFQIADCTSSHDSLTATYASQPAKYTNSRYHDEEADPAKYRPYRDALDTAFELHGYIISMKKERYDYASSVLAKLQITPHHYVPYSYNSQLVWDEMQKFNNGSLQYHKDSHNLKMFSHRMAHTGMLFDFVNDQTAKMNSWRFFFEDDIEIHPDVTIEDARIALAKGMEIGAADGIIYLGICGPGKQDLEPAVKLVRGVTARRSHGTCTHAYGVTKWRAAGLLSYLDKVKVPEHYPSLAYMYFDILTRAYGMTVTRAYILGFNLKSPVPQTFRAKQSHVGLIFQDRAKYPSFITPKKNATSADPKKYATTADPPHVDSADPPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP40</accession>
    <name>A0A8T0GP40_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphatidate cytidylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G174500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP40"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="14576" checksum="122283CADDC36383" modified="2022-10-12" version="1">MTLLDCPTATVNPACVHKVPYVFDFECEKKLMLSRVFAGLISACYVSSIVIAAMSRTVEPGRSLGRDSSQGFVEPLREEREDVPLKGLIAPLDSMPPVDFAFAYGSGVFTQALHSRARSNEVCVSEFWKPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GP83</accession>
    <name>A0A8T0GP83_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G169600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GP83"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11685" checksum="A69BC06F8E12C283" modified="2022-10-12" version="1">MLRVYHSGNLGRSRLFRSYKLAPDNGSTTCWAPHNLRHHKLEEECYRSLTSQAFSHEWTKASSDKGFLAMIELWEAIMVSLCLGRCRNQPTLESNQVANPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQ60</accession>
    <name>A0A8T0GQ60_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CASP-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G132800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3 8">Homodimer and heterodimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cell membrane</location>
            <topology evidence="1 8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the Casparian strip membrane proteins (CASP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQ60"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006459">
        <property type="entry name" value="CASP/CASPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006702">
        <property type="entry name" value="CASP_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01569">
        <property type="entry name" value="A_tha_TIGR01569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33573:SF50">
        <property type="entry name" value="CASP-LIKE PROTEIN 4A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33573">
        <property type="entry name" value="CASP-LIKE PROTEIN 4A4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04535">
        <property type="entry name" value="CASP_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Casparian strip membrane protein" evidence="10">
        <location>
            <begin position="54"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0559838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="23398" checksum="BBEA2F5CCB742E3F" modified="2022-10-12" version="1">MATGGAWASETFDNGRDFQKTPNHATQAPPMQGAGTPPAMYNPSPVGMSKDSSSFGVIALFLRIAQIVFTLLAFAIMAANKETIYSSYYSYYYYTVSTTYKFSEVKAFIGIVALNCIVCLYAIVQLVQCFINMSSKGSFISSATTGFAMLTFVFDTVLAYALAAASGAGADSAALISDGGCAVDKFCQKAQASVAMSFFAFAVLAASAALYPVRLLRLTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRS5</accession>
    <name>A0A8T0GRS5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G121400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="12935" checksum="81AECD380789E07F" modified="2022-10-12" version="1">MNYLVSTLSCIEPQSLPLDRSASLTAASHSSCKAWVRRGRFEPDDVPRRYSRLRTGFVRMGARGTVDCFRACSSIVLVFRPGLASASNDNSVRSLKAHLGTHLLRLGSRGSESLLILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSS8</accession>
    <name>A0A8T0GSS8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G148100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10963" checksum="DD1E740F01CB62AD" modified="2022-10-12" version="1">MKETKSFEYTMPAQNFKRSPLQKTLNLKRHGLTLQMSTADCTKTYSTTATHKTIALLANKNQAKFCPISNPLTTNASKCQNGRANPPPKPPTKTKPNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GW85</accession>
    <name>A0A8T0GW85_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Retrotransposon gag domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_8G070900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GW85"/>
    <dbReference type="OrthoDB" id="1696034at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005162">
        <property type="entry name" value="Retrotrans_gag_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032567">
        <property type="entry name" value="RTL1-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15503">
        <property type="entry name" value="LDOC1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03732">
        <property type="entry name" value="Retrotrans_gag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Retrotransposon gag" evidence="2">
        <location>
            <begin position="135"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="43176" checksum="B813C295532CA7B6" modified="2022-10-12" version="1">MECKEEQNPVSVTEEEKINKASFAHEVTQHDKRSTSGQSCPSSSSKDSRHEIFDFNASANEDRLKKRKGDPQIYEVNEQAKFIVCLTNMLPKFIATIPPCFAGTQDKRKLDTWLIKVENYLRSIQVKSDRLKISIATTLFDGYAADWWYNRTKHVEEGHELPVLSWENFLNIMEQTFVPTETRFPIQDKLAVLKQTGSVPSYIAKFLSLAIHLENSSESEKVSRFIDGLKPTPSFYISSKRPTSMLEAINLAEKWAYSSVEEGEIITHKRRKIVTRTPSPIKTDRQLPYPSNNRVEAHNHPNRSNISKRLTDAEMTEYRKRGLCFNCSGHGHTFFQCTQRFLWHERMLQHPRSIPPMRGFHSIPSPLVFRRFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWC3</accession>
    <name>A0A8T0GWC3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G011500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWC3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="48" mass="5596" checksum="52A6F06A5090D689" modified="2022-10-12" version="1">MLLCFQFTANLLASRISFFDLWTWASQSTLPILVDKVAETVFLIFRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY10</accession>
    <name>A0A8T0GY10_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="17">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_9G189000</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0563004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000074">
        <property type="entry name" value="Potassium channel KAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000123">
        <property type="entry name" value="Potassium channel KAT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.630">
        <property type="entry name" value="Helix hairpin bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045319">
        <property type="entry name" value="KAT/AKT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021789">
        <property type="entry name" value="KHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45743">
        <property type="entry name" value="POTASSIUM CHANNEL AKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45743:SF2">
        <property type="entry name" value="POTASSIUM CHANNEL AKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13637">
        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11834">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51490">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="15">
        <location>
            <begin position="386"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="566"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="664"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="KHA" evidence="16">
        <location>
            <begin position="839"/>
            <end position="923"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0563004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="951" mass="107416" checksum="A7BD3B08016B5228" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H018</accession>
    <name>A0A8T0H018_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G175900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H018"/>
    <dbReference type="OrthoDB" id="5125733at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112">
        <property type="entry name" value="DOMAIN PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33112:SF12">
        <property type="entry name" value="HETEROKARYON INCOMPATIBILITY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="1">
        <location>
            <begin position="214"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="741" mass="83463" checksum="660FAB2D3F26AB84" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0F5</accession>
    <name>A0A8T0H0F5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G186300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0F5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="111" mass="12799" checksum="DCB34C0043FC8921" modified="2022-10-12" version="1">MTIQNMCYRHAFKSYLPKTLEKNMKKHVFGGILDLWQLIRVIGFRIVYRLLLGNSSSSCTVLLLLFTFGKRTGSGSWKFEEIGFGWRWFGALSIVAPLLPQFPVVAHKSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1C4</accession>
    <name>A0A8T0H1C4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G182300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1C4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13611" checksum="A8E7964582A6D6E7" modified="2022-10-12" version="1">MSILNFLGSSRLCCLGGIRLVPFSPVPCAWLGHGVQASRNGDGDSMDDGMFKVVLESGAWQLWQVWVTTSSRLLSRVCRRLECGQFRERRRTWIYLHDGDGLVILAFPGCMLGRPAISLLGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2T4</accession>
    <name>A0A8T0H2T4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin/FtsZ GTPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G128000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2T4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="5">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0564649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="138" mass="15663" checksum="07DE69812074ABB7" modified="2022-10-12" version="1">MREPDRDGVLEAAVLGAWHQQGRHSGGFATQGGDRKDVFFYQADDEHYIPRALLIDLEPRVINSIQNSEYRNLYNHENVFVSDHGGGAGNNWASGYHQGEQVEEDIMDMIQSRRLSLLPLYCWRNGFRYGFVSSGSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H322</accession>
    <name>A0A8T0H322_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L34, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_8G167500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H322"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3980">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_bL34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_bL34"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035742244" description="50S ribosomal protein L34, chloroplastic" evidence="5">
        <location>
            <begin position="22"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="116"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="127"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0565135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="137" mass="14293" checksum="C47B40F2D1399531" modified="2022-10-12" version="1">MAAMALSTSMSALSLATPASSLKLASSASNARCGLVSSFTSSRVVSSFSSSSFAGVALRPTTFGLPIVKRGFSLVVRAGSPCMGCTKRSRSRKSIARVSGYRARQATPTGRNVLKRRRAKGRKVLVTKSNPSSGKFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3G2</accession>
    <name>A0A8T0H3G2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_8G147600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3G2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045103">
        <property type="entry name" value="RNF5/RNF185-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018957">
        <property type="entry name" value="Znf_C3HC4_RING-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12313">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00097">
        <property type="entry name" value="zf-C3HC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="22"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="12">
        <location>
            <begin position="142"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0564884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="239" mass="27221" checksum="8B6025FF95FC3034" modified="2022-10-12" version="1">MEMGQGSAHKHQAEFPRSILECQICLAPPTKPVATSCGHLFCWPCLFRWIQDEPKPCPVCRTMVTIDINITPIYGSHEEGSTDAGCSDPDQGGNSDGVIPPRPNPPTRTINIRIDTGSDQIISLAATSEQIINGSLLAVNTLMEVNHRNERARRELRAALEIERARVHMLRRERRHLTAGLNYLRRRNYALIHEAGQRVRRQGEERQAFLNWVRNSARQHFARFEEQLVASQYVNDHQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H850</accession>
    <name>A0A8T0H850_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G187300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H850"/>
    <dbReference type="OrthoDB" id="1841769at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035873904" evidence="1">
        <location>
            <begin position="28"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="12409" checksum="86EE88DCF37D6182" modified="2022-10-12" version="1">MSSQIRAVILSVVAVTLMCSVFSVIDAKVCGGDADCLTNNADGTCVSGTCKYLCHSNYKDCDHDMDNGCECNILTDEANCGGCGRYCPSPYNAKASCEAGKCVITDSDEDFFIPGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9Q7</accession>
    <name>A0A8T0H9Q7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G178500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9Q7"/>
    <dbReference type="OrthoDB" id="681454at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050511">
        <property type="entry name" value="AMPK_gamma/SDS23_families"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780">
        <property type="entry name" value="AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13780:SF128">
        <property type="entry name" value="CBS DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="447"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0568000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="488" mass="53011" checksum="AB35FF2C8DCA5DB2" modified="2022-10-12" version="1">MAGFFHARQAGDLAVGKPPLHKYPKNLSVGEALKALKSSDDSELSLWEELCPLTEKPIKEAHGNAREIVSHVSSNQTASNGDGSGCLQVPIGSKETLWRCVGKIGMVDIICFLARDESLADQAAALRTPASSIVSDTAFAIQHVDSRSKLIDALAHVLDGAQHLVVSIDRSISSRLARYNSLPKPRRGFSQTISKPKQGKSLDSTWSLPPRISAHGVQEYCWLTPEDLLQFLLSCIGLFSPLPMMTIQQLGIIRMDVLTVKADADAITALPLIQRAAREITAVAVVEVDDSHNTQELKLVGEISPFTMKSCDEKAALALATLSVREFLAFSRDCDCPPNSLVQLVETRLCAKMEILQMTPRESLLSDSDSPVSFPSPLSTSTFNGPLATIYSLDSGEESSSDEDIYAVNHSPTGPFSSGLHRTSHSYSKGRLAPNMCRPWSSLVAVMAQALTHRVGYIWVTDDDNSLLGIVTYLDIIHCILGHLYSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAX3</accession>
    <name>A0A8T0HAX3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G030100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAX3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="9660" checksum="D837E90BA4C8FDA3" modified="2022-10-12" version="1">MTSTTTAATSPRLDNTIIQTCHQRHHGPYFHEAECEFRWSSHRPKTGPIHLQSNFIITPNFETGPTGHSICSSPLRLTTHYNRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC50</accession>
    <name>A0A8T0HC50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G048400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="16788" checksum="C015A1D0EE6C3C05" modified="2022-10-12" version="1">MSGMGRGSRTSSPKSNSSRHSSPSPKQATKPNSPEEGQVIRPHSVPSNREQGTDHQGTSSGKSSTGGSIVNYVKKNRKAVQKYYKSTGVPITPGEPSEITVHSVPLRTKIGTPHLIGDELGTPSNKGSSFFLSASHNGVRDFHRRVTPKKQQNSER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDP0</accession>
    <name>A0A8T0HDP0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G124800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8701" checksum="4727E2542E4CFD51" modified="2022-10-12" version="1">MLVGFICMLDEEPTRAIKTQERQLLVDVWTSTCFEAIASLVLIVGVSYRHWVEMRSSEKVPTGNVCKHRAIAPLRGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFH2</accession>
    <name>A0A8T0HFH2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G159400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047126">
        <property type="entry name" value="RNF141-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109">
        <property type="entry name" value="RING FINGER PROTEIN 141-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12109:SF5">
        <property type="entry name" value="RING-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="4">
        <location>
            <begin position="920"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="863"/>
            <end position="918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0567772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="978" mass="111363" checksum="FEF66716682F4474" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJD1</accession>
    <name>A0A8T0HJD1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G196000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJD1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035750118" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="41" mass="4683" checksum="09105FDBBC23CFDE" modified="2022-10-12" version="1">MRVVSVLSLICWTSMRVSGLCVRMSIIYKGFALRPLCMTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKK1</accession>
    <name>A0A8T0HKK1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG002700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="6836" checksum="B2DB7561628FA0CA" modified="2022-10-12" version="1">MVQNLPAVQRSRLGRSTWQNGRTSVMLGGNIGLLHGRCGSAQRCISRGAGLLRPGDIASSDARAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLA7</accession>
    <name>A0A8T0HLA7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG015500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLA7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8752" checksum="387D7BBA61D4EE69" modified="2022-10-12" version="1">MGIAMRRDQRHKQQHNFGTDKKFESHSYLIRVPTGRGAPRKLWRVRFRCFRICVVLVCFVEEIYVVYCGEGFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLV4</accession>
    <name>A0A8T0HLV4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ABC-2 type transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG046500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLV4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="ABC-2 type transporter transmembrane" evidence="7">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0571830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="186" mass="21839" checksum="F407F2D11B6618AA" modified="2022-10-12" version="1">MYSAIPYALAQVLIEVPYVLVQATLYGLITYSMLQFQWTAAKFFWYLYILFISFLIYTFYRMMMVAITPNFILASICSAFFYTLFNLFTGFLIPRPDIPPWWIWYYWFCPLAWTIYGLVVSQFGDYSGPMEVVGSTVPTTIQGYLCHTFGFRHDFLAAVGPVLVLWMMLFAGIFIFAIKFLNFQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM90</accession>
    <name>A0A8T0HM90_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10 14">Peroxisomal membrane protein PEX14</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 14">Peroxin-14</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_VG055300</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 14">Component of the PEX13-PEX14 docking complex, a translocon channel that specifically mediates the import of peroxisomal cargo proteins bound to PEX5 receptor. The PEX13-PEX14 docking complex forms a large import pore which can be opened to a diameter of about 9 nm. Mechanistically, PEX5 receptor along with cargo proteins associates with the PEX14 subunit of the PEX13-PEX14 docking complex in the cytosol, leading to the insertion of the receptor into the organelle membrane with the concomitant translocation of the cargo into the peroxisome matrix.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with PEX13; forming the PEX13-PEX14 docking complex. Interacts with PEX5 (via WxxxF/Y motifs).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Peroxisome membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the peroxin-14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990429">
        <property type="term" value="C:peroxisomal importomer complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005778">
        <property type="term" value="C:peroxisomal membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005102">
        <property type="term" value="F:signaling receptor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016560">
        <property type="term" value="P:protein import into peroxisome matrix, docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000217">
        <property type="entry name" value="Peroxisomal membrane protein PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025655">
        <property type="entry name" value="PEX14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054154">
        <property type="entry name" value="PEX14-like_M_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006785">
        <property type="entry name" value="Pex14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23058:SF0">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN PEX14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23020">
        <property type="entry name" value="PEX14-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04695">
        <property type="entry name" value="Pex14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="5 14" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 14" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisome membrane anchor protein Pex14p N-terminal" evidence="17">
        <location>
            <begin position="45"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Peroxisomal membrane protein PEX14 central plants" evidence="18">
        <location>
            <begin position="133"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="77"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00053920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00064754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF04695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF23020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0571936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="320" mass="33850" checksum="344C6AE112193E9C" modified="2022-10-12" version="1">MCLGDRYGNGGAQGAVANETGAGVAVEGVEKPKADPWKLETQPIRKDQVVNAVKFLSHPKVRGSPIVHRRSFLERKGLTGEETDEPFRRVPDPSSSEAAATAAAAKDVQAQAPSSQPIAPAQQVVVAQKPRELSWGQKLLGLGVIVAAGAGVGVVTKAYILPKFKSWVRSILLDDGETDKKISPHTEGLPVEPPVNEAALADNAAAAAASEVAAAMREFSHARAKESLQLGSIIKALETQTLELKSALSGMRDVVNNNSNNNYGYNNSSSELTPTTTLGSIRLAKALGWPRLRPDCAQIALQKRCLILASLLSSGSSFME</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMR3</accession>
    <name>A0A8T0HMR3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG054500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMR3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="273" mass="29663" checksum="983CED59C82E2A16" modified="2022-10-12" version="1">MASDLTSSKEQINEVKQLLLCLIHPTLPPSPVPVRTFTPTTERQGEPLTAQVIKPTTLPLQDPHYTIPLDIRERRVSSRLNRIEEVHASVTQTATIRHHHEDRSMPIVVHPMVQSPSWGSGETVPITPNSLLQNFTNKMPIGAATSTDISGSFGAMSNKLSPQPATESMPRSPVRCFPVGMSSCGLVGCSFENPSSEGIPEEGDYTKTHNGVTTWGMATQAEKEPEVRAPRPNFKYGPLPRLNENAIAANSLCFVYHVDHGDVIIAQGQAGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNC1</accession>
    <name>A0A8T0HNC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG084400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="12745" checksum="E8C8101F3097D1E4" modified="2022-10-12" version="1">MVDQVHAGEHPRGDPHQQRFPNGVSDDLGQENRASPVGAGRGGGIPSPERSSDSAIPLREEGNAAGEDGRDISDAPSVDVSDDSSGDEGAHQWGDSDDETDASIAALEEGSDYSLVPRIRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ32</accession>
    <name>A0A8T0HQ32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG132400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="136" mass="15396" checksum="572E4BA25CA31277" modified="2022-10-12" version="1">MTQGGRQQFGRQNRDEESWQRPIGQGRGHSINELKKRTQCNYCRQKGHWEKECQKKLTHEGTSGANITMAEPSSVFIVATEQSAESFNADSGCSYCRMSGHCVQCPAGNMTKNTLYPTCSRSTVLINSSDHWHDHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQB8</accession>
    <name>A0A8T0HQB8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG153500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQB8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035892505" evidence="1">
        <location>
            <begin position="33"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="61" mass="7382" checksum="A8F4FE4C4ABAB257" modified="2022-10-12" version="1">MCSIFLLMPISKFHQFMVFSCLDLFLTRLVSSNVERSYHYSDQRTNLTLWYDETRLIQVRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSI3</accession>
    <name>A0A8T0HSI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_VG217300</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15840">
        <property type="entry name" value="SNARE_Qa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF38">
        <property type="entry name" value="LD27581P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14523">
        <property type="entry name" value="Syntaxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="168"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="119"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0573874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="261" mass="28941" checksum="94AB08C2F2810CE3" modified="2022-10-12" version="1">MSFEDIETGESGGGWKQDRSDGVAAGIFWINTSVSTYKRLVNTLGTQRDNHALRERLHATEQKIGQLVEETVAMLKEENEADLVSSSATKKIRGAKLAKDFQLLLQEFQTAQKAAQSRQRKNAPFLLPASSSSGSNSGRGEREEETGLLRQSQQSVVEVNESEVLFNATVIEERDQGIQDIQQQIGEVSMIFKDLAQIVSNQGYIIDDIEANIESSVSTTLQANIHLTRAARSQKLLEYWKCVILAVVGTVLFAFLIIMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSV1</accession>
    <name>A0A8T0HSV1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BRCT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG235100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BRCT" evidence="1">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="10183" checksum="32784E6A960F1D36" modified="2022-10-12" version="1">MLEALYAGATEADNVFDRVTHIVVFHNDRQTIPERNIIRSLGGQPEQDMVRFSNFLSPGGVKINIVYHDWLDACLKAKKVLPVQDYDALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTV9</accession>
    <name>A0A8T0HTV9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG250700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTV9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="348" mass="39222" checksum="F48C091E6FFBB69A" modified="2022-10-12" version="1">MQLQLLSCHQSGNSGRELYDSVCVGGVKKLEMTTGREIARGEKGAKVAYQESSRCSSRGSTRIKPGGMGESIPPALRSSGSKPTSPRLEGEIGVKQREGSNGSPSVDELLKTVKRLEKGFLSLADAVIAEIEGMREDARSWQEEREELWKTVMAFHSHQKSDMEPVRHRLDSLEKRASDIEKHLQSRDPETRIPANDRLEELERRAYELEKQVKKQHAHLLHGPLQTGQEKPVFKEELVYRPGNLLEQHRSKLEGSKRLGLSSRNSDSEEAILAVRKEIEEFHGGRVGDRGMSSENGELQQTELENNVSAVSAVIHDLHKLQEWCKLVENDQAMRLQRLTESVSEHHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUL4</accession>
    <name>A0A8T0HUL4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG285400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="13826" checksum="97E25B73CA66DCB9" modified="2022-10-12" version="1">MECGASSSPSLAPSKNFKANPGYASVPPSPFPTPFPTPFPPRSPIPASRLPPLSPSPRLSAPNSRAARRRPALRARRDSTSCISQVKWLPLQRFRRRGHRAWACTPEEGTQSGGHPSKIQGPGLEWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUS5</accession>
    <name>A0A8T0HUS5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG244700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUS5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="37564" checksum="E649D5F2BB86ECDD" modified="2022-10-12" version="1">MGNCNHKFHITCIAKAALNNKQCVMCRSPISSRFYEMLGLQHVMPPGHELDRWNLPLDQLPKKELNYYDWGKSLAWNPETMTHQLSTANDAGMDDLSWMTHDYEVEMRAREIPDAKDREFFCRNFGGHWSIHGNRFFRFPKPEVVVDADGKRREVEQDYGQLDEYKMYDRTPVGRALVLARLEEAIQHRRTFNEESFKYSDLCYWVITKKFDDALQKIVNDWRRALRAEDNSSRWSRNRIEKIVQGTVAKIEKAKELWNGKNSKKRNRDNPYEDDPEWGEDNRRSLDRVEEEYRSGGTITHPSQRRQTRRSNANNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWH1</accession>
    <name>A0A8T0HWH1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG326900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7612" checksum="9EDAA7338071B65A" modified="2022-10-12" version="1">MGTALSLVMLHTPCFHHMARDATPHLKIVYFWTKFLKKTFTIHLCFLLHGLINWTNLMNHSPTSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWV5</accession>
    <name>A0A8T0HWV5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG327200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="36871" checksum="95FF846DB2EBDF52" modified="2022-10-12" version="1">MSSSTWEDRATPAQTSPPDSYHPDQPYAHSDHDSRKGCNDDPGTCNYGYASPPSLPRYYSDQGSVHDNNRVKGHGSIPHSHHGSVKDFPINYGGSGGGNGGDYQGSVRLSGSRNGSHHSSVKDFGSDHGSGHSHFCSYLAKNEAKQDNNSVTLQEDFVRPSMSWLDRRSFHMGESCAVPLNWKYHPTLRQVPPEEQQNYRHAKIEEWLSTSHKRKPKENFGAYLWRASALANSELTHRKKQCWGDDYRDPLDRFVMRLFYGMKLKLERTESIFLGIYEETDILDILREECEELSNKGQLPIDQRSILYTPIIISEMQEISNIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXD0</accession>
    <name>A0A8T0HXD0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG336900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXD0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="58" mass="6592" checksum="4313B32763A25590" modified="2022-10-12" version="1">MSTRTAFLRWLSALPRTLRKNPLLNFELYSNFSANFSLASRSFSFGNLRISTTEGSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HXQ2</accession>
    <name>A0A8T0HXQ2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G039200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HXQ2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056284">
        <property type="entry name" value="AIR9-like_A9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055474">
        <property type="entry name" value="DUF7046"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31149">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31149:SF7">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23080">
        <property type="entry name" value="DUF7046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23197">
        <property type="entry name" value="IG_AIR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIR9-like A9" evidence="3">
        <location>
            <begin position="553"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7046" evidence="2">
        <location>
            <begin position="663"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="400"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="173"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="524"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0575910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="769" mass="85010" checksum="AD756F716575D172" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ07</accession>
    <name>A0A8T0HZ07_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G076900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ07"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011692">
        <property type="entry name" value="Stress_up-reg_Nod19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07712">
        <property type="entry name" value="SURNod19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11790" checksum="6B8DCBB31CBF671F" modified="2022-10-12" version="1" fragment="single">ESHEGFRTHEFVTDQQILFKRGKVQNYRFYLIRGGFSCGEVGNGRFSREMVMEDGTTMLVPLFETYLLHWQMCEYVFAKSDRDMLKYCNLTVDLKKGGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZB2</accession>
    <name>A0A8T0HZB2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G048700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1037" mass="116663" checksum="5C03A1DA491F2EC6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZQ8</accession>
    <name>A0A8T0HZQ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G075100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Fe(2+)(in) = Fe(2+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28486"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:28487"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZQ8"/>
    <dbReference type="OrthoDB" id="73465at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="FE(2+)/MN(2+) TRANSPORTER PCL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="4" id="KW-0926">Vacuole</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00044464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0576376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="298" mass="31910" checksum="8402878D64134B80" modified="2022-10-12" version="1">MERGKSWRHEGGKFKRRLSSLSIRRKQALEEPLVGDGERRDGDVEEGSNSGRTARVAGKERPKEGGWGGDYLKSIVYGGLDAIVTSFALVASVSGGDLPAGAVLVLGFANLIADGISMGYGDFLSSTAEKDYSANQQLIADWEIENNIHGEMLELVSAYQEQGMEKDDADKVVDILSKYKDIMADQKLTMTQGVLPPDPEDSPFKNGCVTFVSFLAFGSTPLLTYLILTPITDSKDIKFLGACIVTILALALLGAAKARISGERILSSMAVVVFNGGIAAAAAYGISYLLNNVFGIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7J9</accession>
    <name>A0A8T0I7J9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Apoptosis inhibitor 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G102100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the API5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7J9"/>
    <dbReference type="OrthoDB" id="19224at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043067">
        <property type="term" value="P:regulation of programmed cell death"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008383">
        <property type="entry name" value="API5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12758:SF19">
        <property type="entry name" value="APOPTOSIS INHIBITOR 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12758">
        <property type="entry name" value="APOPTOSIS INHIBITOR 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05918">
        <property type="entry name" value="API5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0053">Apoptosis</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="484"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="421"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="543"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0579482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="578" mass="63366" checksum="8F499277FB12EB1C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7N1</accession>
    <name>A0A8T0I7N1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G105600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7N1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="13835" checksum="1B22FED8864B88FA" modified="2022-10-12" version="1">MDSQELDTMPVMSSQPTNSRRRSRDEEPPVPRRRRKIPSNRSLVIVFEVEPAFNGLPEGVFAGQFHNEDTEVHAWSEVEGVGHYRWLQGPMNHLPRKQQLEFIADVMRQIFIFLRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I844</accession>
    <name>A0A8T0I844_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G116600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I844"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="47031" checksum="EC0A2576BC447FE6" modified="2022-10-12" version="1">MAPRPSRNLKEDATVLGDMKDDVAMDPTLWGNLKDYVAMEIIYAKVPFHKFFQLRLVCKEWNHLAGDRKFLEDHFKEYLVPEPYFYIPGGCEYLDPRPYLELPNGRCMNGFVTIDINSEDVGWIGLNNPWKDRGGCCAVNGLIYSETVPSPDYLSPPKRTPEVVQKRAESRRQEVFNIHTRVRHKLPPSQLTTAIPVVGMLVDTSVRPYGFKVIQGCGDLGTQIFDSRTNAWELRPSRLPAGIAARLDSFRSGSPHWSYHGSVNCNGLLFIACDDGDKILVYNEKEDIWSTLYASRRDAWWSFLSIGSWHGRLFKAYRVIDGIDLTWDLTWVNPSRHEWELYDQMPANLCDWLFKDYKFSKVVLDYCRNYILICYDLTSQEDSKTKIVLYDLATKSWKKFTFRLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8J0</accession>
    <name>A0A8T0I8J0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_4G047200</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8J0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000101">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000146">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase IOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF77">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 15" id="KW-0732">Signal</keyword>
    <keyword evidence="3 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035843592" description="Protein kinase domain-containing protein" evidence="15">
        <location>
            <begin position="31"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="243"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="309"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0578753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="624" mass="68314" checksum="BA6EA09A2437828B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9N1</accession>
    <name>A0A8T0I9N1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G177200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9N1"/>
    <dbReference type="OrthoDB" id="29308at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030124">
        <property type="term" value="C:AP-4 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin/coatomer adaptor adaptin-like N-terminal" evidence="6">
        <location>
            <begin position="60"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="697"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="757"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="992"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="762"/>
            <end position="771"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="807"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="863"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0580490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1038" mass="113270" checksum="EA69162AE7834D4D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9P6</accession>
    <name>A0A8T0I9P6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/hydrogen exchanger</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_4G117000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>K(+)(in) + H(+)(out) = K(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29467"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Na(+)(in) + H(+)(out) = Na(+)(out) + H(+)(in)</text>
            <dbReference type="Rhea" id="RHEA:29419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9P6"/>
    <dbReference type="OrthoDB" id="196264at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015386">
        <property type="term" value="F:potassium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015385">
        <property type="term" value="F:sodium:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051453">
        <property type="term" value="P:regulation of intracellular pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098719">
        <property type="term" value="P:sodium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004709">
        <property type="entry name" value="NaH_exchanger"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00840">
        <property type="entry name" value="b_cpa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="SODIUM/HYDROGEN EXCHANGER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110:SF127">
        <property type="entry name" value="SODIUM_HYDROGEN EXCHANGER 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01084">
        <property type="entry name" value="NAHEXCHNGR"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0050">Antiport</keyword>
    <keyword evidence="6 11" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0915">Sodium</keyword>
    <keyword evidence="8 11" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="3 11 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="118"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="221"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="308"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Cation/H+ exchanger transmembrane" evidence="14">
        <location>
            <begin position="40"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="451"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="512"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="560"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0579687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="615" mass="67761" checksum="4C5C63E3BC8E85A5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA06</accession>
    <name>A0A8T0IA06_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G179500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA06"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035921750" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11997" checksum="F5C77EAAF944A73D" modified="2022-10-12" version="1">MLPHSNTLLLSFLYILCTAPTKTIKHQFHNNLTTISQQSHTNLTTISQQSHNNLTTISQQSHNNLTTISQQFQIPGAETPSHNLKQIPIACTKTKKIKSLPQKLQPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICE6</accession>
    <name>A0A8T0ICE6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G178800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39211:SF1">
        <property type="entry name" value="ABNORMAL SPINDLE-LIKE MICROCEPHALY-ASSOCIATED PROTEIN ASH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39211">
        <property type="entry name" value="CHROMOSOME 7, WHOLE GENOME SHOTGUN SEQUENCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="733"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1476"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2621"/>
            <end position="2703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3637"/>
            <end position="3660"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1365"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1477"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2621"/>
            <end position="2630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2655"/>
            <end position="2682"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2683"/>
            <end position="2698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3637"/>
            <end position="3650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="3720" mass="409942" checksum="BCA32BA7CF8EE9B0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICM8</accession>
    <name>A0A8T0ICM8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G189100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICM8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="54" mass="6237" checksum="F3F46AC26CBCA68F" modified="2022-10-12" version="1">MLRVARNITSPLCLHCPDPKLRYVKKANGDLQFHTFLHPITSHLSRSLIAHIYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICU2</accession>
    <name>A0A8T0ICU2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G197000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICU2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF59">
        <property type="entry name" value="EXOSTOSIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="Exostosin GT47" evidence="6">
        <location>
            <begin position="222"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0580757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="574" mass="65466" checksum="2A053FE91FA21337" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDB2</accession>
    <name>A0A8T0IDB2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G174200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDB2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="258" mass="28902" checksum="BCCE79784C137B0D" modified="2022-10-12" version="1">MPVKLKGMPSAEGRGGSIWLPLRCCLRACCARGRRCARLGRFLFPYWYISALYHLSLSPSSSPSPFQRESVPLPAAPRPQPSLSLALSASRVPLPGPSSPSLPAGRRRRRLRRRVLLRTVECWAPTQRTALQFAVWRRPTSLPLSATTHVPTHALARRWGPAGARLSAFGKWDLFLHLFQCQVAISGLGNGQPCQRPDACSYFTISCGHFLRRFEVALLIKGLQGPRKMHSIKLILKVLHFTHVNSQDLAHVYVTWRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGI1</accession>
    <name>A0A8T0IGI1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G092500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="46663" checksum="75A87B711459ECFE" modified="2022-10-12" version="1">MEMEMERAEDAFVHTEVDTGVGQSVSVGLDAALWSTLPKELIRFICARLPLPKLLRLQHTARVENWKLNLDDSEFRQLCAKTHTNMCAIMVPEYGSGVVFNLELHSGESVLWRKLKLPIEEPDYVSRGRSNIMSSADGGLVCFALKFQSPENEETMVILVVNPLTGDCKELPAHGMCPVELKMMQLVMDRETKLYQVILVGPKSGNGGGTQAMLYHSGTGVWANAKEFTGLFFGLQYCFYVSVMKYDMIGPCVYDCAAEKLHCLDRDTFRSIYISNHRVDVALLQDHFFALTHEDHGKAGHLQNYGLCEYQIQLQQDGVRCLKLKDHHEVQTELLVSGTENIWLCKGFLLLTGCRANLTTDPNDVPIYGAWLCNMSTGDWLEIQSFSTFLGDWQYYFDISTNLLCELQWDAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGJ9</accession>
    <name>A0A8T0IGJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alpha-taxilin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G093900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the taxilin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019905">
        <property type="term" value="F:syntaxin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026183">
        <property type="entry name" value="Taxilin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127:SF13">
        <property type="entry name" value="GH01188P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16127">
        <property type="entry name" value="TAXILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09728">
        <property type="entry name" value="Taxilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="141"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="303"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="395"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="497"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="600" mass="66909" checksum="16431DBCC18C642B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHB6</accession>
    <name>A0A8T0IHB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_3G050500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb-like" evidence="2">
        <location>
            <begin position="46"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="475"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="377"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="391"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="496"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0582309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="508" mass="57063" checksum="6FD8B2CD4F1635AF" modified="2022-10-12" version="1">MSVQEEAQGGRMEGGGREEEEDDNDAYLKRIRDEEGVERQDVCAKRRRIRSENWGASETLQMLELRKAVVQTSTAKGSDAWKQIAQQLAAMNPESQARSFKQVAQRWDTLVKVYVSVEEHCCESGRTCGDVIDERQKRCKTEYRQLWHELIAEGNPGKRRAPSKASVQPDDQTPARLVNDAPQVVTTLTQKFGEIAKSFTEMLDTIDRSITSSEERSQAPGHMNKNIVTGCNWELEEDQAGLERVVFVSGLKKQQDETKAEVARATQSMADTMQSISEAASTSESFCLEVDQRDWSMVIRRLSEISQRYREISVQGIRDEVGADVHDPNSQQQTTSAARSTHDHPNNSIQRSLSLTSSFYISGKLCKKTLSSLNTTRSEKSCSSGKRDNGSPASPATSTATFAGLPDIVHLSPKSDCESLSGSKSVDQGGWTNLCFRNSRFKKGEKLVLRKEKKKRTERRTSILKFQERLTLEEVGEKSSRSMTRTMTRFGPRVQSSEEQKHRSLSET</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHU9</accession>
    <name>A0A8T0IHU9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G130700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048544">
        <property type="term" value="P:recognition of pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00028">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.90.10.10">
        <property type="entry name" value="Bulb-type lectin domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000858">
        <property type="entry name" value="S_locus_glycoprot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32444">
        <property type="entry name" value="BULB-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32444:SF108">
        <property type="entry name" value="OS02G0527900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01453">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00954">
        <property type="entry name" value="S_locus_glycop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00108">
        <property type="entry name" value="B_lectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035869843" evidence="4">
        <location>
            <begin position="23"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="464"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="5">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="6">
        <location>
            <begin position="365"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0583364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="508" mass="55925" checksum="E458D54BF5EB1DB4" modified="2022-10-12" version="1">MKRCKALLWVLHLLIRFLPVWTLRLQNLTLSSSRLNVGDTLISPSGHFELGIFPYPAESGRYYLCVRYAAPIQQVAVWVANREIPLSQQSYLELSSPNGNLQLSDPDNNVAQIPWSSNTADAGVGRAQLLDTGNLVLVDNDGNPIWDSFKNSSITDTLLPGQYFYKIGNINLTSWLTKDDPATGNGTYTFGWGTRANMSGSILQLAWTSPKVFSVWRGGTYIPGPDDTNPHIIPDVDYVYFDATQGNLYFPSTPANIVIISGGDLVSSTTLKRLTLDADGGLRIWQFTVGTSKTWTAEANWVVTERHSQCFTIGTCGPFSLCNMSPFGSLDRVQCTCPYGFKPINPDDLSRGCTPIERLSGSDLCNASKVNLTVLNDIDMPWGGDYRNLTGAESANCQAECLKDCKCAGAVYSKNEQRCWMKMTPLYNLGYPTVTLHGSDRTAFIKISLYQPPSPESDQGKFKLWMIALVVVGGLLGLGLLVACCVYYRRENHITGPGGEPLHPPWRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHW6</accession>
    <name>A0A8T0IHW6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit O, mitochondrial</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G063100</name>
        <name evidence="9" type="ORF">KC19_3G063400</name>
    </gene>
    <organism evidence="8 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHW6"/>
    <dbReference type="OrthoDB" id="1262810at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0582476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="229" mass="24956" checksum="144EE47BC845093B" modified="2022-10-12" version="1">MWRSQQLVRSSVALARAAAGTSGQPAGRAVRSFAAQAEAEQHVEVPVPMYGVAGKYASALYVTAVRKNVLDPVETELQQVIGAAEQNPVFADFLRDPSVSKTVRMKAVEELFGQTKFTDVTKNFLAVLAENGRLAQLQRIMGCYSELLHAHRGEVQALVTAALELSPAELEDIKSALKGYLKPGQTLKVEQKVDRSIIGGIVVDIQDKHIDLSIDTKIKQMEKMLAEAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IL02</accession>
    <name>A0A8T0IL02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nuclear transcription factor Y subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G150200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the NFYA/HAP2 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IL02"/>
    <dbReference type="OrthoDB" id="1097733at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016602">
        <property type="term" value="C:CCAAT-binding factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.2430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018362">
        <property type="entry name" value="CCAAT-binding_factor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001289">
        <property type="entry name" value="NFYA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12632">
        <property type="entry name" value="TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02045">
        <property type="entry name" value="CBFB_NFYA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00616">
        <property type="entry name" value="CCAATSUBUNTB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00521">
        <property type="entry name" value="CBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00686">
        <property type="entry name" value="NFYA_HAP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51152">
        <property type="entry name" value="NFYA_HAP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0010">Activator</keyword>
    <keyword evidence="3 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="175"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="292"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU367155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="326" mass="34846" checksum="786B31694AFD9A02" modified="2022-10-12" version="1">MQISFGDEHTGGSDAAAGDWCLGRSDQLRSSFATISMQAPSSAPADTESLLPTMQALPPQPGVLLYFAEPQSRDESSYATTGAEDQPPRPPTGVPASGDYILPHTQLELGHSMARAAYPFADPYFGGIVAAYGAQAVIHPHMLGVQQARMPLPSEMMEEEPVYVNAKQYHGILRRRQSRAKAESENKLIKSRKPYLHESRHQHALRRARGNGGRFLNTKAKEGDPKSNSDGNHGSHEGQSSQGGNTSNARASHSGMEMLNGQGDSVNYHTNMLAHGQNNAYLNLHPPQSFHSSAFHTLPGGSESGDGGSNGNNLVVSGSEHTAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILM5</accession>
    <name>A0A8T0ILM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G159400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin U/P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019901">
        <property type="term" value="F:protein kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20604">
        <property type="entry name" value="CYCLIN_AtCycU-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013922">
        <property type="entry name" value="Cyclin_PHO80-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15615:SF121">
        <property type="entry name" value="CYCLIN-U1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08613">
        <property type="entry name" value="Cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="36"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="240"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="39"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="288"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="40410" checksum="5A78447903AEE79B" modified="2022-10-12" version="1">MPPSCRTPGFLGSHPKADEDDVFGADASRMQLTVSNLRSSAKGASSQGSSTLTFEAPDIDDDSNASSDREVPKVLNVLAAVLERLVARNEQFANAPSQQGKKLTIFHGLRAPSISIAKYLERIFKYTSCSPSCFVVGYVFLDRLIHRQPDLLVTSLNVHRLLVTSVMVATKTLDDVHFNNAFFARVGGVSVVELNRLELEFLFRLDFKLSVSVSMFESYCTYLERDISAVDKKPERVERSLPAFGSPPISSPGTPRGSAPGTPTEMSPRFKKRVPHGLPVAYASRKNSSSYQASSHQPSSYQTSSHQTSSYQTSNYQPSSYQTSSHQPSSYQTSSHQTSSYQSSYQPSYQPTYQQPLPQYKSLFAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INA3</accession>
    <name>A0A8T0INA3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">BCAS3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G201600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Preautophagosomal structure</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006914">
        <property type="term" value="P:autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042594">
        <property type="term" value="P:response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045142">
        <property type="entry name" value="BCAS3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022175">
        <property type="entry name" value="BCAS3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048382">
        <property type="entry name" value="BCAS3_WD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268:SF0">
        <property type="entry name" value="BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13268">
        <property type="entry name" value="BREAST CARCINOMA AMPLIFIED SEQUENCE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12490">
        <property type="entry name" value="BCAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21034">
        <property type="entry name" value="BCAS3_WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BCAS3 WD40" evidence="4">
        <location>
            <begin position="188"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="BCAS3 WD40" evidence="4">
        <location>
            <begin position="382"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="domain" description="BCAS3" evidence="3">
        <location>
            <begin position="650"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="954"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1074"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="678"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="688"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1112"/>
            <end position="1122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1134" mass="119603" checksum="243236BDE60B7596" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUU7</accession>
    <name>A0A8T0IUU7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G067900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUU7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071277">
        <property type="term" value="P:cellular response to calcium ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009704">
        <property type="term" value="P:de-etiolation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090333">
        <property type="term" value="P:regulation of stomatal closure"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044690">
        <property type="entry name" value="CAS_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209:SF1">
        <property type="entry name" value="CALCIUM SENSING RECEPTOR, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34209">
        <property type="entry name" value="RHODANESE/CELL CYCLE CONTROL PHOSPHATASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="252"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="400" mass="41990" checksum="3DBD0FF54E1210C7" modified="2022-10-12" version="1">MAQAMRAMQVTALNGSLAGSSQNVDTSVVSHRSSKRFPKSRRPALSLRASMEDGRDAQVAVVAPATIASFVVMADAGAANALTAEDVTETYMKVQSTASQVSNVASQTFGVAKSVFGQVVETVKPAVTAVTPYVKQSADFVYKTVFPFATDIEKQAEKALQSSGVDTKPVLDAAKSAASAAGEVGKYVEGAQPSISSTLQNVLSSDPIVLATGAGGLLLLYLLAPSVFSSISYAARGFKGELTAPQALDLLSKEDYILIDVRSEKEKAKSGVPSLPRNAKNKFLPVPVEELPGKVRGQLRNVRKVEAEIAALKISSLKKINKGSRLVIIDSNGDIAKTIARSLSGLGFNNTWVITDGFDGGRGWVQSRLGTESSGTSFTEILSPSRVISSGTKLLQASSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUW6</accession>
    <name>A0A8T0IUW6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G129000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUW6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="75" mass="8292" checksum="D341353DAD0F6836" modified="2022-10-12" version="1">MSFRDPKPNKAAVHFIAMRADFKLCLPVGNMCHTLLTILGISTRIIPDCQSTQAGNFESRCIVHAGRPDLPKRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV99</accession>
    <name>A0A8T0IV99_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G103100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018971">
        <property type="entry name" value="DUF1997"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34133">
        <property type="entry name" value="OS07G0633000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34133:SF8">
        <property type="entry name" value="OS07G0633000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09366">
        <property type="entry name" value="DUF1997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="339" mass="37527" checksum="1514A314B34F7B81" modified="2022-10-12" version="1">MLLCGSFNNTLIKPRADSFLRSLDNLVHQPDRDQIATMASVQCTSLSTSRVLTERTSSSACSSTSSFQRVSAPFSARTCHSSVSPTSSDLKYGAVERQSSEHFHSSFFHNNTRSPFKTNISPAKKPVGTLIRAQHVSFKATRTVTIPFKEGAFPANEYLKETERIVKVTFPDSTRIEYLGDQKWRSRLRPLTFINVTATPTVEMRVSFEKGSLRLYSNNLFLDFTGVPESFAVADFSFLLDGSMRATLRSPEAVTVRHNSDFAGSVSLGLSTDLPAAFALIPEGIVTRAGDEILDRIIGAMEGALLQGIIRDYNIWCRMKSRKVAKPRQPVVPLRTSTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVJ5</accession>
    <name>A0A8T0IVJ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G132100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Activates SnRK1.1/KIN10 and SnRK1.2/KIN11 by phosphorylation of their activation-loop 'Thr-198' and 'Thr-176', respectively. Required for the regulation by SnRK1 kinases of the transcription of a large set of genes, the modification the activity of metabolic enzymes, and the control of various nutrient-responsive cellular developmental processes.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Associates with the SNF1-related protein kinase (SnRK) complex. Interacts with AL1, a geminivirus (TGMV) protein essential for viral replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the protein kinase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd14008">
        <property type="entry name" value="STKc_LKB1_CaMKK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000747">
        <property type="entry name" value="Serine/threonine-protein kinase GRIK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000206">
        <property type="entry name" value="Serine/threonine-protein kinase Ssp1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346">
        <property type="entry name" value="MAP/MICROTUBULE AFFINITY-REGULATING KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24346:SF39">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GRIK1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 13" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="113"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00054601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00066296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0586979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="390" mass="43411" checksum="181457016E4B5611" modified="2022-10-12" version="1">MDKQCTYCCGLFWFGNKSSAGRDTKSSSKPGIVKRISKEHLLSFTAEENDKATKNGVESQTPAQINLYSLPYKANVGSHGPVLVLPFLRAGVKETRHEFQSNDSDGSKMVNEYVQKCKIGTGSTGKVVLYQSKKDEKLYAIKILHKPRLTKLRVSPTETAMMDVLREIAIMKRLDHPNVVKLYEVIDDPESERLYMVMEYAEGNWIFEGSGPPGGIGEAVAREYFRDVVAGLSYLHNHNVVHGDIKPENLLISGDGSIKICDFGCSRMFEGENDELRRSPGTPVYTAPECCSGSHYSGRTADIWALGCTLYCMVMGRYPFLGDTFPSVFEKIVKQPLFIPEGTDPDLADLLRGLLCKDPRKRMPVEAVATHPWLSRGFGQVQAPSYKAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IW76</accession>
    <name>A0A8T0IW76_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G205900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IW76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11676" checksum="A9D28FEF81B443D2" modified="2022-10-12" version="1">MTVQELARLQAEAQAQATQLTQMLASSDLSQLAARRLLTPPGSIRHTEKVTTPLLCQAPGMDCLPGEEVRCEIGRHAGCDCEYIRVCFPRAAECSHYNATHVTTCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWW5</accession>
    <name>A0A8T0IWW5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G175800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWW5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11506" checksum="D02E593C68E4CD10" modified="2022-10-12" version="1">MLCSSPRSHSLCSLANETNFASLAELVRYQSLEFWSFVCGFVDWFVGGGVRRGGVWRSWEDLRSWEVVWSGEEWDLGEGRLGGGRGRGGRGGGEGRKEEVLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXD8</accession>
    <name>A0A8T0IXD8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G240400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MIP/aquaporin (TC 1.A.8) family. SIP (TC 1.A.8.10) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXD8"/>
    <dbReference type="OrthoDB" id="1580043at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015250">
        <property type="term" value="F:water channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="entry name" value="Glycerol uptake facilitator protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044222">
        <property type="entry name" value="SIP1-1/2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46739">
        <property type="entry name" value="AQUAPORIN SIP1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46739:SF3">
        <property type="entry name" value="AQUAPORIN SIP1-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="Aquaporin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0588404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25361" checksum="C97F80001F1E39DA" modified="2022-10-12" version="1">MDRDLWLAEMAAKDAIITFLWMTCMSAVGVGANLVVEDLKLAHDIPIVLVAGAMFAVLPAFLSLASWMGGASWNILGLVAFAYMGESFNRHTVVSIAVRLMAQMVAAVWTAVFIMRFTPPEYKHMVGGPTLQVDPFKGVLVEGILTYMLMLVSLMTTSRGSCSPRTKLIISVVTTVMLVILGGAYTGPSMNPTNVYGWAVINRQHESEEHYAVYWLGPIIGTLAAVKTMKLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYY8</accession>
    <name>A0A8T0IYY8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Acyl-CoA oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G203700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYY8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000013">
        <property type="entry name" value="Acyl-coenzyme A oxidase 4 peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000014">
        <property type="entry name" value="Acyl-coenzyme A oxidase 4, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000021">
        <property type="entry name" value="Acyl-coenzyme A oxidase 4, peroxisomal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045008">
        <property type="entry name" value="ACX4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43188:SF1">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43188">
        <property type="entry name" value="ACYL-COENZYME A OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="8">
        <location>
            <begin position="83"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="7">
        <location>
            <begin position="197"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="6">
        <location>
            <begin position="306"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0587946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="470" mass="51293" checksum="79AEBA40BBA6E141" modified="2022-10-12" version="1">MERVMTAEGMDEKGWHRLARISQQLQPTGVPGLLSPGQLESMPTLGIGLPALDVASAFPQATAASTFPEAVSDYFGVEDLLSQEDIALRKRVRGVMEKHVAPVMTKYWEKAEFPFEIIPHLASLKIAGGTIKGYGCPGFSILSHALVCAELSRVDASCCTFALVHSSLCMSTIGMLGSEEQKQKYLPSLARFDTVGCWALTEPAYGSDASSLNTTAVKVEGGWLLNGQKRWIGNATFADIAVVFARNTQSNQINGFIVKKGTPGYKTTKIENKIGLRMVQNADIVMKDVYVPDEDRLTGINSFQDTNKVLAVSRIMVAWLPIGVSMGVYDICHRYLQERKQFGAPLAALQINQEKLVRMLGNIQAMFLLGWKLCKIYETGKMTPGQASLCKAWNTLRARETVALGRELLGGNGILSDFLVAKAFCDMEPIYTYEGTYEINTLVTGREITGIASIKPSASGKTKGLLVSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J273</accession>
    <name>A0A8T0J273_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G289100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J273"/>
    <dbReference type="OrthoDB" id="203097at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF30">
        <property type="entry name" value="SODIUM_METABOLITE COTRANSPORTER BASS6, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0589068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="425" mass="45807" checksum="744D6009C8C4B6AB" modified="2022-10-12" version="1">MTAQWSSLCLQHRGANVSVDASGARNGPLQRRSYARSIQLHLKGQPRFLKQCTSWRQIDVTSFNPLGHGRKTIRRALPTGKVTCSAGAADQNEKTQEAMPGLTGLKKWEDALKHVNVYIPHAVLFSTVLALSYPPSFTWFTTKYYAPALGFLMFAVGINLSIEDFKHAVERPGPIALGLAGQYVLKPLLGVVFAALSVRLLPLPEAVGSGLILCACVSGAQLSNYATFLTEPKLAPLSIVMTALSTALAVVVTPLLILLLLGTRLPIDLVGMITNITEIVVVPVAAGLFLNRFVPQVTRLIRPILPLLSLLTTCCCIGSPLAVNIHAIRSPFGLEILLPVVLFHTSAFIVGYKVTEATFPNAPDLTGLARTISFETGMQSSLLGLALANKFFPDPNVGLPSAISVVIMSLMAFGLVIYWNKHKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3A2</accession>
    <name>A0A8T0J3A2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA 3'-terminal phosphate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G095900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3A2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003963">
        <property type="term" value="F:RNA-3'-phosphate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.20">
        <property type="entry name" value="RNA 3'-terminal phosphate cyclase, insert domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023797">
        <property type="entry name" value="RNA3'_phos_cyclase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037136">
        <property type="entry name" value="RNA3'_phos_cyclase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000228">
        <property type="entry name" value="RNA3'_term_phos_cyc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036553">
        <property type="entry name" value="RPTC_insert"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096">
        <property type="entry name" value="RNA 3' TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11096:SF0">
        <property type="entry name" value="RNA 3'-TERMINAL PHOSPHATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01137">
        <property type="entry name" value="RTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="EPT/RTPC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNA 3'-terminal phosphate cyclase" evidence="1">
        <location>
            <begin position="79"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="475" mass="51295" checksum="9DC846985CCD5499" modified="2022-10-12" version="1">MLSWALKSINSPGFLLTSPVSSSIPLSHSPRILKREGFECKPTTPILPNSLRPTISDSTGSSAAVYRMEDVVKIDGAVMKGGGQVLRNSACYAAILGKSVQFVNIRASRKSPGLRSSYVEGLEIVAKLSKCTLVNACEGSQEVSFIPRELAIRDSQFSEPSCTDPVSSAYEIHTTNGATPLVLQGSLPVLLFSPNVTEMTLTGGTDMLISPSIDYMKRVLVPLLHRHFNVVVDVDIVRRDFMPSGEALVKVRTHPTESLPPISLRDRGSVARVSSIVYGYGKADDQFVEAAKMALHETLRDNGINMDASFSSDMQGAETEHPLVCRALVYAEMTTGCILGGGSRIPKGEVVSDPKELMSSAVLDLVKQLAHGGCIDEYLQDQLVIFMALADGVSEVVTGPITEHTEHALEVAHRMTDAKFFVTPVAGSDRFEIRCEGIGHMSRSRHPISNGSAFVTCAQHERQDLGDVLEPVNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3G6</accession>
    <name>A0A8T0J3G6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G019200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3G6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="91" mass="10214" checksum="BBEACF5EFF0A2800" modified="2022-10-12" version="1">MPKHWDHYPSSLSHKSPMWSGIYDMNAEISFKDYATSMFYFLCGLPAPPSYSPIANISGPVAAASPALCLACFNLPNKVSETWRTEFHKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3U7</accession>
    <name>A0A8T0J3U7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G081900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035946247" evidence="1">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7226" checksum="CC588A26BD03B42A" modified="2022-10-12" version="1">MLSIPLQLLLPSVCMHGVHLQVATILDSESSTQQYSLETYLFNPEALGPIHFCEYLGDSERLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6N4</accession>
    <name>A0A8T0J6N4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G101200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6N4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032991">
        <property type="term" value="C:protein-containing complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19499">
        <property type="entry name" value="RecA-like_ClpB_Hsp104-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000017">
        <property type="entry name" value="ATP-dependent chaperone ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.60:FF:000011">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1780.10:FF:000004">
        <property type="entry name" value="ATP-dependent Clp protease ATP-binding subunit ClpC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000025">
        <property type="entry name" value="ATP-dependent Clp protease subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000010">
        <property type="entry name" value="Chaperone clpB 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="entry name" value="Clp, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.10">
        <property type="entry name" value="UVR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050130">
        <property type="entry name" value="ClpA_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11638:SF155">
        <property type="entry name" value="CHAPERONE PROTEIN CLPC1, CHLOROPLASTIC-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="Double Clp-N motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="102"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="11">
        <location>
            <begin position="519"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0590461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="936" mass="102555" checksum="3263D563493EA945" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7D3</accession>
    <name>A0A8T0J7D3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial</fullName>
            <ecNumber evidence="6">2.1.1.201</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ubiquinone biosynthesis methyltransferase COQ5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">COQ5</name>
        <name evidence="7" type="ORF">KC19_1G119800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10858"/>
            <dbReference type="Rhea" id="RHEA-COMP:10859"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:84166"/>
            <dbReference type="ChEBI" id="CHEBI:84167"/>
            <dbReference type="EC" id="2.1.1.201"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; ubiquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with PYURF; the interaction is direct, stabilizes COQ5 protein and associates PYURF with COQ enzyme complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Mitochondrion inner membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
            <orientation evidence="6">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.201" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7D3"/>
    <dbReference type="OrthoDB" id="6329284at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031314">
        <property type="term" value="C:extrinsic component of mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008425">
        <property type="term" value="F:2-methoxy-6-polyprenyl-1,4-benzoquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000064">
        <property type="entry name" value="2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF24">
        <property type="entry name" value="2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01184">
        <property type="entry name" value="UBIE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0831">Ubiquinone biosynthesis</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="178"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00046387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0590691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="306" mass="34060" checksum="8259653C3FDDE1CF" modified="2022-10-12" version="1">MAMALRWRGCARLVFHRSGSRALHLGPLEQPDSSQAQSQPESKFTNFGFREVPEQEKSKLVGEVFSNVASNYDLMNDLMSGGLHRLWKDRLVSKLAPFPGMQHLDVAGGTGDVAFRVVDAIQKAEQRVPGTTLADADEEDQTRVYVCDINPNMLEVGKKRAKERGLGNAACLVWMEGDAEALTLKDESVDGYTIAFGIRNVTHIDRALKEAYRVLRRGGRFLCLELSHVSTPGFKEMYDAYSFNVIPRMGEVVSGDRASYQYLVESVRKFPNQERFGSMIADAGFKEVEYENLVGGVVAIHSGFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7I6</accession>
    <name>A0A8T0J7I6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G188600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11578" checksum="FE011C19EF2F7358" modified="2022-10-12" version="1">MFVHKVTFRVASSIQKLVFDCSCLPGSDSSVKLHCLLRYFFFSYFGWHIPVKVTEVVANVSGYEAELLGRIITLAMLNIVGCCCFPTSPVTYLSSGMLASHTTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J972</accession>
    <name>A0A8T0J972_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G164700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DESIGUAL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J972"/>
    <dbReference type="OrthoDB" id="2015495at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009606">
        <property type="entry name" value="DEAL/Modifying_wall_lignin1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052222">
        <property type="entry name" value="DESIGUAL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31769">
        <property type="entry name" value="OS07G0462200 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06749">
        <property type="entry name" value="DUF1218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="191" mass="20372" checksum="7F26C2B8599E43E6" modified="2022-10-12" version="1">MGSASGLVIGVSLVFYLIAFGLALGAMARRSKGDLTTIDEEMGTLMCKYTTDIATGLAAGAFLFLFVAQMFVMGVTRCLCCGRGYKPGASRTFAIILFIFSWMSFIVASAALLAGASQNKIQTKGLFYSTQTDVSCRQVQKSLFAAAAAFTFITMLMTEVYYVLIEMAREGDSTWQSYGLGGPSVGGSAYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J983</accession>
    <name>A0A8T0J983_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VDE lipocalin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G165700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J983"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046422">
        <property type="term" value="F:violaxanthin de-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015994">
        <property type="term" value="P:chlorophyll metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010028">
        <property type="term" value="P:xanthophyll cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012674">
        <property type="entry name" value="Calycin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022272">
        <property type="entry name" value="Lipocalin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044682">
        <property type="entry name" value="VDE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010788">
        <property type="entry name" value="VDE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33970:SF1">
        <property type="entry name" value="VIOLAXANTHIN DE-EPOXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33970">
        <property type="entry name" value="VIOLAXANTHIN DE-EPOXIDASE, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07137">
        <property type="entry name" value="VDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50814">
        <property type="entry name" value="Lipocalins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00213">
        <property type="entry name" value="LIPOCALIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035759194" description="VDE lipocalin domain-containing protein" evidence="1">
        <location>
            <begin position="17"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="VDE lipocalin" evidence="2">
        <location>
            <begin position="121"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="473" mass="52042" checksum="DEBC7BD7D4C4001D" modified="2022-10-12" version="1">MAAVQALLSLPHLACGNPLQPSAQSVSAPAAQFRSLFSRPCLGVLLPRSGQSSWIASRGRCRARAQRECRNTEAASASSTEVRESTSLYQGFALQAAAAIAAGVLLWGGSNALAADPLKTCACLLKECRVELAKCIADPKCAANVACLQTCNGRPDETECQIGCGDLFENKVVDEFNDCAVTRKGCVPQKQDEGRFPVPAPEALVPEFDTTRFTGTWYITSGLNKTFDTFDCQKHEFTAEPQKLSGNLSWRIATPDGGFFTRGTVQNFVQDDKQPGILLNHGNEFLHYQDDWYIPASRIENKPDDYVFIYYRGKNDAWDGYGGAVVYTKSPKLPESIIPELQAAAKKVNLDFSKFTTTDNTCGPEPPLIARLEKTVERGEEFVEKEVEEGEKFVEKEVEEGESFLVAVTKKLGQAQQSLFGRLGKGAQQLQLDEERFLQELGVEEKQMLKDLEMDAADVGKLFGNAIPIRKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JA06</accession>
    <name>A0A8T0JA06_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G199300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JA06"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031969">
        <property type="term" value="C:chloroplast membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010027">
        <property type="term" value="P:thylakoid membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09912">
        <property type="entry name" value="DLP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001052">
        <property type="entry name" value="Probable transmembrane GTPase FZO-like, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051943">
        <property type="entry name" value="TRAFAC_Dynamin-like_GTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43681:SF1">
        <property type="entry name" value="SARCALUMENIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43681">
        <property type="entry name" value="TRANSMEMBRANE GTPASE FZO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="Thiamin phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine phosphate synthase/TenI" evidence="3">
        <location>
            <begin position="245"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="545"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1097"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0591753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1103" mass="119542" checksum="D137766045494D94" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAM2</accession>
    <name>A0A8T0JAM2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G209700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="57" mass="6467" checksum="12C26D6C00882434" modified="2022-10-12" version="1">MQKKADRRLAGVPRQFEAQEQGCRNSSRILLHAPQQITLHPSLETSHPSAKGTWRCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD97</accession>
    <name>A0A8T0JD97_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G296400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007750">
        <property type="entry name" value="DUF674"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33103">
        <property type="entry name" value="OS01G0153900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33103:SF19">
        <property type="entry name" value="OS09G0544700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05056">
        <property type="entry name" value="DUF674"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0592993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="35150" checksum="F78BC4F13A5D31AA" modified="2022-10-12" version="1" fragment="single">MADEICENCGKPSRKQDDSIPITLLVSRASKQVVCVEVGKEFVDMLMGFLTIPISCLVRVLNNAAMIHRPDEIKIPPKIPESVPYTPGPKKSDPHFALTAIANVFDSVAKLEAEKMTVDKNTLLQAKPTFPFGAGKLLKTKGAPKEGEEMHYPDSGFFSCGAACNFSTAIANTKCPKHKKPMLTPIKMVEDAPIDPTDEKALAAAALAQKEGGYVKPETKFMVTNQLEIFASSSMKALIALEMIRSERVGDLDTMEVLVIADEVLQLLKASLLSTNVLNDVFGKYCVNAKRNMPMSNGTPFFPACGDKPCCNCNRMGVPLHPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G3N0</accession>
    <name>A0A8T0G3N0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G031500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G3N0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36586">
        <property type="entry name" value="PROLINE-RICH EXTENSIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36586:SF51">
        <property type="entry name" value="PROLINE-RICH EXTENSIN-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="38607" checksum="99E82464AADC5A02" modified="2022-10-12" version="1">MASTHGLVVLIIAALTVLIFCNIHIDAARVCNNVDNCGYSHVKCPNRPHSDRFCKDGQCGIKCKGSYRDCDCKQSNGCETDVEEDTLNCGRCKHKCPVPANSVATCNDGECGFKCKPGFKLYNYCCVAVTPPPPPPSPSRPPPPFVYSSPPPPPFLSPSPPPPVVLSSPPPPVVLSSPPPPVVLSSPPPPVVFSSPPPPLVLSSPPPPVVFSSPPPPLVLSSPPPPLVLSSPPPPLVLSSPPPPVVLSSPPPPVVLSSPPPPVVLSSPPPPVVLSSPPPPVVLSSPPPPVVLSSPPPPEVLSSPPPPEVLSSPPPPEVLSSPPPPSVLSSPPPPVVLSSPPPPEVLSSPPPPSVLSSPPPPVVLSSPPPPLVLSPPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4W0</accession>
    <name>A0A8T0G4W0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G049800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small hydrophilic plant seed protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4W0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009737">
        <property type="term" value="P:response to abscisic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038956">
        <property type="entry name" value="LEA_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022377">
        <property type="entry name" value="Sm_Hydphi_plant_seed_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000389">
        <property type="entry name" value="Small_hydrophilic_seed_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671">
        <property type="entry name" value="EM-LIKE PROTEIN GEA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34671:SF19">
        <property type="entry name" value="EMBRYONIC ABUNDANT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00477">
        <property type="entry name" value="LEA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00431">
        <property type="entry name" value="SMALL_HYDR_PLANT_SEED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0553921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9178" checksum="055484681451EED5" modified="2022-10-12" version="1">MSGQDTQDLDARAAAGETVVPGGTGGKSLEAQQHLAEGRSKGGQARAEQLGHEGYVEMGKKGGSATNEMSGGEAAEAVGREIDESKFTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6B2</accession>
    <name>A0A8T0G6B2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dynamin-related protein 3A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G102200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6B2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001027">
        <property type="entry name" value="dynamin-related protein 3A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF21">
        <property type="entry name" value="DYNAMIN RELATED PROTEIN 1, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="6">
        <location>
            <begin position="53"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="5">
        <location>
            <begin position="683"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="589"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="794"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="605"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="624"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="636"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="797"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="856"/>
            <end position="871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="889" mass="98035" checksum="70663775DA32E7CD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G722</accession>
    <name>A0A8T0G722_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_12G043000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G722"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048544">
        <property type="term" value="P:recognition of pollen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001480">
        <property type="entry name" value="Bulb-type_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036426">
        <property type="entry name" value="Bulb-type_lectin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000858">
        <property type="entry name" value="S_locus_glycoprot_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32444">
        <property type="entry name" value="BULB-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32444:SF108">
        <property type="entry name" value="OS02G0527900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00954">
        <property type="entry name" value="S_locus_glycop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51110">
        <property type="entry name" value="alpha-D-mannose-specific plant lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50927">
        <property type="entry name" value="BULB_LECTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035805760" evidence="3">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Bulb-type lectin" evidence="4">
        <location>
            <begin position="32"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="5">
        <location>
            <begin position="349"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0553839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="47428" checksum="33389F87262C8838" modified="2022-10-12" version="1">MAISMWTLIAAVVVAVAVAANAQPVSRLAPYTATITAGKTSAPLVVLKTQNYIVSLEGNPCAITIRHLFSSKVAHLLWTSAYHYSSIIPLNANTCTLKLTSGGNLQLIALTRGFPTTVWTSLSTGMGIVKMALENKFDSGELQLLTAGNVIKYSSFQEKEFALLPRQKISANTQTLVAPDKFFAKDNPQILFSGHRYTMMLVSGDLILYSTFKQIGKQYWSLKKTLAKNVDIRFVASASIVPSVGGIGLYKLDGTLLWTFGKISIGSSNPHDTYLSVDPDGNLRTYVLVKGQFWRKDFEAITNVCDLPDACGPYGVCNNGKCSCLPSWVPIDSKDSKKGCKTQAPMKTCSSGKQTFRSYSGYDQVYNKYDWRGLKISKAECEFRCYGRQPTCGNCSAYFYDDNTKMCYLTNEVRTLRKVTDLKKTVNVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7I2</accession>
    <name>A0A8T0G7I2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Epidermal patterning factor-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G153200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the plant cysteine rich small secretory peptide family. Epidermal patterning factor subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7I2"/>
    <dbReference type="OrthoDB" id="1937916at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010374">
        <property type="term" value="P:stomatal complex development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039455">
        <property type="entry name" value="EPFL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33109:SF4">
        <property type="entry name" value="EPIDERMAL PATTERNING FACTOR-LIKE PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17181">
        <property type="entry name" value="EPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="4 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035824352" description="Epidermal patterning factor-like protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0555223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="149" mass="16215" checksum="95EF16F28AFA8B2C" modified="2022-10-12" version="1">MSVGVVMCLTSALWLLAFFPASAVARIGPSGALASTKTISYLERTPGVFSEAKHEMAELKPQSIERMDLRTAPQEIDSIFDFHSKIGDGGSIRRSLVGSSPPTCRSKCGTCTPCKPVHVAIGSPHGVISETEYYPEVWRCQCGNRYYMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7L7</accession>
    <name>A0A8T0G7L7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G044800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7L7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12937">
        <property type="entry name" value="GUCT_RH7_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059027">
        <property type="entry name" value="DD_DDX21-DDX50"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012562">
        <property type="entry name" value="GUCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF8">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26142">
        <property type="entry name" value="DD_DDX21-DDX50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08152">
        <property type="entry name" value="GUCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="144"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="12">
        <location>
            <begin position="353"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="645"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="653"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0553858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="691" mass="74060" checksum="63929741678ADEE3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9X6</accession>
    <name>A0A8T0G9X6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G009700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9X6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035910644" description="Secreted protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="76" mass="8448" checksum="BB17F094AE250969" modified="2022-10-12" version="1">MWPDWCPRGMRCDAMRCSALLCYAMLCCDGDGGGRERGRGQTTRGREGGRGRMRELQPRATEVALTLQVPAPTSTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAD8</accession>
    <name>A0A8T0GAD8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_12G161900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
            <location evidence="1 12">Extracellular space</location>
            <location evidence="1 12">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAD8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010497">
        <property type="term" value="P:plasmodesmata-mediated intercellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000280">
        <property type="term" value="P:regulation of root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000025">
        <property type="entry name" value="germin-like protein subfamily 2 member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0052">Apoplast</keyword>
    <keyword evidence="7 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 9 12" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035968317" description="Germin-like protein" evidence="12">
        <location>
            <begin position="21"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="13">
        <location>
            <begin position="59"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="30"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0555334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="218" mass="22653" checksum="79B3AEA8F2CBA01C" modified="2022-10-12" version="1">MAKLTVGFVALALLVAVVAAGDAGPINDFCVADLKSALLFNGLACKAPSMVTSDDFSFTGFRAAADTNNPLGIGIIPGFAGVNYPALNTQGLSLAKFNYAKGGLVPPHTHPRASEVITVLKGEVHVGFVDTAGKLFAAKLKTGDFFLFPVGLVHFQLNVGSGHAVTVSVLNAQNPGVQLMASALFGASPEIKDEVLSRAFGIKDDMTKMIKKGFMPAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDN8</accession>
    <name>A0A8T0GDN8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_11G055200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the potassium channel family. Plant (TC 1.A.1.4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDN8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Potassium channel KAT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.70:FF:000123">
        <property type="entry name" value="Potassium channel KAT3"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
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    </dbReference>
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        <property type="entry name" value="cNMP-bd_dom"/>
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        <property type="entry name" value="cNMP-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003938">
        <property type="entry name" value="K_chnl_volt-dep_EAG/ELK/ERG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045319">
        <property type="entry name" value="KAT/AKT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021789">
        <property type="entry name" value="KHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45743">
        <property type="entry name" value="POTASSIUM CHANNEL AKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45743:SF2">
        <property type="entry name" value="POTASSIUM CHANNEL AKT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ank_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11834">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01463">
        <property type="entry name" value="EAGCHANLFMLY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="cAMP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81324">
        <property type="entry name" value="Voltage-gated potassium channels"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51490">
        <property type="entry name" value="KHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="12" id="KW-0407">Ion channel</keyword>
    <keyword evidence="10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="11 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0630">Potassium</keyword>
    <keyword evidence="6" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <keyword evidence="7" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="100"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="162"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="16">
        <location>
            <begin position="392"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="569"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="13">
        <location>
            <begin position="666"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="KHA" evidence="17">
        <location>
            <begin position="869"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="739"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="780"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="792"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="14">
        <location>
            <begin position="817"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="847"/>
            <end position="861"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0556464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="973" mass="109014" checksum="A031F5CD67FA47C6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEE8</accession>
    <name>A0A8T0GEE8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G100100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEE8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6601" checksum="DBFC5CC307F0C775" modified="2022-10-12" version="1">MHTKHRHTRHHFVLLFPIISNALFNTHLVLSHHDFVSARKTNRREPIPVGLNTLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHH3</accession>
    <name>A0A8T0GHH3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G144600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12091" checksum="0D24DA5D6C8667F4" modified="2022-10-12" version="1" fragment="single">YKIQTSQTVASKPRTHHLSTEKLGVRTFNIILIPIEQSFKQKQQSTHLKKISSFHQRTVSLMQIALLFRRATPSQTMQTSVPLHMKFLLNGLAPSEQRELTAFTGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJX5</accession>
    <name>A0A8T0GJX5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)</fullName>
            <ecNumber evidence="5">1.2.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G132600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + 3-methyl-2-oxobutanoate + H(+) = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:13457"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10497"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83142"/>
            <dbReference type="EC" id="1.2.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterotetramer of alpha and beta chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the BCKDHA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.4" evidence="5"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003863">
        <property type="term" value="F:branched-chain 2-oxo acid dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009083">
        <property type="term" value="P:branched-chain amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000015">
        <property type="entry name" value="2-oxoisovalerate dehydrogenase subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050771">
        <property type="entry name" value="Alpha-ketoacid_DH_E1_comp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43380:SF1">
        <property type="entry name" value="2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0630">Potassium</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="14">
        <location>
            <begin position="123"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00031050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0559836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="460" mass="51469" checksum="38709E28E69DA600" modified="2022-10-12" version="1">MKLPGATTTWARLISRRLLHRPSQSQLQSQAHRSSSSSFTSSGVLSQRRCCSGSSSGEDSDGNQDEFHDFPGAKAGFTSKLKYVPETPAEAVPCFRILDEYGRLIKDSHMPEIDKALVLKIYQNMVTLQSMDSLFFEAQRQGRFSFYLTSFGEEAITIASAAALSDDDMVYAQYREPGVLMWRGFTLNEFANQCFSNDLDYGKGRQMPIHYGSAKLNYATVSSPIATQLPHAVGAAYAFKMDQKPLCSATYFGDGATSEGDFHGAMNFAAVLEAPVLFICRNNGYAISTPAHEQFKGDGVVCKGQAYGVRSFRVDGNDALAVYATVKAARKMAVEESRPILIEALTYRVGHHSTSDDSGKYRKGDEMHHWKTMRDPVVRLRRWLEGEGWWDSDADQQLRAETRNEVIAAMQRAGPRMKQPLANLFTDVYDTIPSHLRQQEKELRSTVARHRQDYPFDVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLX1</accession>
    <name>A0A8T0GLX1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G144600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLX1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="56"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10561" checksum="8578416151CDE64C" modified="2022-10-12" version="1">MRLRATLRGRSGGSGFGYGDGDGDGDGDGKPRLDEGRVRASASSCAELCCVQSGEQTEEEEKEGDGSDGSDVPAMVCLFVGFGCDELRFWRMLVMLLLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMS9</accession>
    <name>A0A8T0GMS9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WD repeat-containing protein WRAP73</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G166500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMS9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005815">
        <property type="term" value="C:microtubule organizing center"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990811">
        <property type="term" value="C:MWP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052778">
        <property type="entry name" value="Centrosome-WD_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220">
        <property type="entry name" value="WD REPEAT PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16220:SF0">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN WRAP73"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="52421" checksum="78EDBF6D7F754EBE" modified="2022-10-12" version="1">MEFSDTYKHSGHCVFSPDARFLAVAVDYRLVIRDAVSLKVVQLYSCLDKISHVEWAPDSEYILCGLFKKAMVQAWSVSQPEWTCKIDDGCAGICHARWSPDSRHILTTSDFQLRLTVWSLVSTACVHVPWPKHGSRAVAFTRDGKFAAVATRRDCKDYINMLACRGWEAMGTFGADTIDLADLEWSPTDSNIAVWDSPLEYKVLVYSPDGRCLFRYSAYDNALGLKTVAWSPCGQFLGCGSYDQVVRALNHLTFKPVVEFTHPFALKGSSNAVVFKEIEEAWHSDMQSTYTNGTSGPGNMARTKDSPNDTQTRVRYKVAEFPITVPSQKPLPDKPNPKQGIGLMAWSADSRYLFTRNDNMPTALWIWDVARLELASLLIHKDPIRAAAWDPIFPRVAICTGTPYLYMWTPSGAACVNIPLSHFVVSDLKWSPEGTSLVLKDREAFCCTFVPMLSELEIDDADANDEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNP5</accession>
    <name>A0A8T0GNP5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G155400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNP5"/>
    <dbReference type="OrthoDB" id="591557at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="CDD" id="cd22157">
        <property type="entry name" value="F-box_AtFBW1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.50:FF:000008">
        <property type="entry name" value="F-box only protein 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="2"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="419" mass="48200" checksum="674992164F7235E9" modified="2022-10-12" version="1">MARLLENLPPEILENVLACLPVHVLCRLRLVCKKWNYLISQPEFAPRQASYVLFTPKVLQVKAAATEIGMDWEVLDMAENRFYKLSDSFVAKYMMLTQGHDGIWLKYTMAAGGGLIYAVYYGREGVDREHHIVCNPVSKDFHRIKEPKPFCYHDSDIVAMLVDNATKSYRIVTVEPYQEDRGLAGRLRRGRVYLYDSTTMQWRKLCEAPPENKYRAYSSIFMGDVFYALFMDYSVAPSCPKLYSCDTETGVWSYIDVKLHPPSSQKDKLQLVMILGRLFYVEYHGLVSSLRRIRRIQNTLRATDASTIEVSVKVGIWEILLAKRELINVTQISKMLSISRIILDERPETILRDHAIAVGCEDSILISSLAHRWKFDLLKNSWYEMPDNTDHMQGTREGTAICHGICAGLVHLDLREMSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQI0</accession>
    <name>A0A8T0GQI0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G181900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQI0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="409" mass="44627" checksum="2A4F4793A0F76768" modified="2022-10-12" version="1">MAAAVASSPEIESHIYGGSQSLHPEVTSAYTGNGFVTRPYSGNGFVTRPYSSGGFVTSLGNQGREIYSGQQTLSAASSGQQQSAYLSGQASGLQGISAASLGHQTSGLQGISAASLGHQTSGLQGISVSSLGHQTTGLQGISGASFGHQTTGLQGFHSASFGHQTSGLQAISAAKQAIIVAQSQLDQQIEFERQKSVNYELTSMGSSYIASHNEEELPKQYETRWKVFEKVPEMKVEEETRYKPKVSWETRLVPEPKAVIHYDEVEHIELVAEVKYITKSKPEVYYHVLEEESEVPVMEQVLAYEEVSVTRQEPRFVAEDIEEIIRVPVVREVPVTRMKKVFTGKHSDKLIEEYEDPGNFTDAIANSPHRQMSGVNSPSFSHASYDDNDSRHSKLEATTKMNPLPSIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQK2</accession>
    <name>A0A8T0GQK2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Peroxidase</fullName>
            <ecNumber evidence="20">1.11.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_10G093200</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>2 a phenolic donor + H2O2 = 2 a phenolic radical donor + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:56136"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:139520"/>
            <dbReference type="ChEBI" id="CHEBI:139521"/>
            <dbReference type="EC" id="1.11.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="17 20">Binds 2 calcium ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="17 20">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="17 20">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 20">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="20">Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.7" evidence="20"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQK2"/>
    <dbReference type="OrthoDB" id="2113341at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140825">
        <property type="term" value="F:lactoperoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00693">
        <property type="entry name" value="secretory_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.420.10:FF:000001">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.520.10:FF:000006">
        <property type="entry name" value="Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000823">
        <property type="entry name" value="Peroxidase_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033905">
        <property type="entry name" value="Secretory_peroxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31235">
        <property type="entry name" value="PEROXIDASE 25-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00461">
        <property type="entry name" value="PLPEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 17 20" id="KW-0106">Calcium</keyword>
    <keyword evidence="13 19" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7 20" id="KW-0349">Heme</keyword>
    <keyword evidence="20" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="12 17 20" id="KW-0408">Iron</keyword>
    <keyword evidence="8 17 20" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 20" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 20" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 20" id="KW-0964">Secreted</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="21">
        <location>
            <begin position="47"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="17">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="18">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="57"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="90"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="139"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="19">
        <location>
            <begin position="218"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PIRSR" id="PIRSR600823-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0559282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="344" mass="37924" checksum="BE4B98DA708D1C43" modified="2022-10-12" version="1">MRVFLAFQFELTGALVMRRTMLSLVALLVVSLSMYSVQSLGVSINLGLRNGFYDLSCPDVERVVYLTMQMISRRDPDIPADVLRLHFHDCFVRGCDGSVLLDGPGTEKKAPPNDRLEGFQAIDTVKAAVEKVCPGVVSCADILAFAARDSVKINQGPDWRVPAGRRDGRVSIAAEAVSNLPGPEMTISQLVENFGRQGLSKSDMVVLSGAHTIGDAACHHIDDRLYNYPSKSGVDPIIPADFVTELKRKCPKPGLRLQTVDFDRVTSHRFDPQYYHNLVSNKGVLASDQLLWTDKSTRPLVAQNSVKTLFFANFAQAMIKMSKISPLTGDQGEIRLKCRVVNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQM6</accession>
    <name>A0A8T0GQM6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G010600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="117" mass="12860" checksum="8DB11431EA5562FF" modified="2022-10-12" version="1">MADPSGTVPNSNSPLKCHIIHLTQLTSLFIHSLIHHLTTAQNSITLTSNQSNTLHLPATTNATNKTPRKTSTNNRNAPPHSTSLIKHIHGTITRMAIQLIPPQYHQEHKTPQTPTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GR23</accession>
    <name>A0A8T0GR23_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G104300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GR23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035793927" evidence="1">
        <location>
            <begin position="28"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="440" mass="45758" checksum="9F32385562C49E3C" modified="2022-10-12" version="1">MASASAIAVMFVGVVASLLLCSVHVDAAKVWNDPSNCGSWHFKCPCQPPKTNTKSTCVNGKCGFVCSKSQWQDCDNDINAANGNGCETNVDCDPVNCGGCGIICPAPANSTPRCLKGGRCSFQCNKGFKLQIDNTCIPTTTKCGSGCKPPGPNTDSVCQGGKCKSVCHQDFQDCDADVAGICEANVTEDVYNCGSCKRRCPQPNSLPSVQTVNLGNLYRPDFATCSNGTCGVACGVNHHANCDGVATNGCETDLMNAVSNCGTCGKACAEPPNTTGAACISGVCGYLDCSEGFADCDADASNGCETDIPPTVENGCSSSGSCPGDVSNQNFPCPVPPNTVAAKCKGANTCSYTECLPGFIDCDGEVSNGCEVDTTVDGWNDYTQREYCGICKQTDTCNDDITTDCSSVCTVAPYTAFCHTYPMGVLPGMADNEGFCYLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTG7</accession>
    <name>A0A8T0GTG7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Remorin C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G166400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the remorin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005516">
        <property type="entry name" value="Remorin_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31471:SF52">
        <property type="entry name" value="F12A21.28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31471">
        <property type="entry name" value="OS02G0116800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03763">
        <property type="entry name" value="Remorin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Remorin C-terminal" evidence="4">
        <location>
            <begin position="617"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="333"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="492"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="649"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="302"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0560262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="731" mass="81364" checksum="743E4E7630F133F7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV99</accession>
    <name>A0A8T0GV99_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G116000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV99"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="12061" checksum="ED04B841F645F724" modified="2022-10-12" version="1">MPVHNNNATFTDGWGCTWDKDSMLISGTYYRRLPSVGRDAASYRYELLEDEPKAWNYSHLVVQSRVELLQYKSKKKNPRFKMSAETREAILSNVEERQAYNAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVW2</accession>
    <name>A0A8T0GVW2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G165600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVW2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025875">
        <property type="entry name" value="Leu-rich_rpt_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766">
        <property type="entry name" value="PLANT BROAD-SPECTRUM MILDEW RESISTANCE PROTEIN RPW8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36766:SF30">
        <property type="entry name" value="TIR-NBS TYPE DISEASE RESISTANCE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12799">
        <property type="entry name" value="LRR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="976" mass="111045" checksum="D582BF10178CB702" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWL9</accession>
    <name>A0A8T0GWL9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G081000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWL9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11851" checksum="F1998A7A69C1D39F" modified="2022-10-12" version="1">MTDREFHLKPSQQQNHCQHSIYTLQQPVKISQGSESQLAYSTPTSFTRNAEITVISSIASRKITISQQPQRLLSNPKTGVNLKRRSQDEPIRTQNQNTKTITTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX79</accession>
    <name>A0A8T0GX79_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_8G008800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX79"/>
    <dbReference type="OrthoDB" id="691673at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd12203">
        <property type="entry name" value="GT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000032">
        <property type="entry name" value="Zinc finger and SCAN domain-containing 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21654">
        <property type="entry name" value="FI21293P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21654:SF84">
        <property type="entry name" value="SI:DKEY-66I24.7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Myb-like" evidence="7">
        <location>
            <begin position="43"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="146"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="158"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="197"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0563157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="36625" checksum="F3C8BB90FC6A8D57" modified="2022-10-12" version="1">MGENLGVLPMSLQGTHDMNHSDLGALTPNRGRALKKEDRIPQWGYHETKEFISIRAELEKDFTQTKRNKTLWELIERKMKEKGYRRSADQCKCKWKNLVNRYKGKETSEPDYEFTQGKDPADPENGRQCPFFDELDAIFKERAKNSERLSLEAEPGSRAKKKGKRGKTKSSDDDSEDDDDEEESEEDRVVQRKKRKNEKDNNRPRVTAEKYRANSMQEVLEDFFQQQQRVEEQWRESVERREQERRMREQEWREAMEKLEQERITREHMWREREEQRRARDEARAQKRDELFAALLTKLAQDEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXK0</accession>
    <name>A0A8T0GXK0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">40S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G079900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXK0"/>
    <dbReference type="OrthoDB" id="1727351at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.60.20:FF:000001">
        <property type="entry name" value="40S ribosomal protein S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="entry name" value="Ribosomal protein S17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_eS17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_eS17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018273">
        <property type="entry name" value="Ribosomal_eS17_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="Ribosomal_eS17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10732:SF0">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="Rps17e-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00712">
        <property type="entry name" value="RIBOSOMAL_S17E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="16604" checksum="5070A337181B9CDA" modified="2022-10-12" version="1">MGRVRTKTVKKASRVMIERYYSRMTLDFQTNKKIAEEVAIIPSKRLRNKIAGFATHLMKRIQRGPVRGISLKLQEEERERRMDFVPEESAIKTDVIEVDRETIELLAHLNMPQLPGVVQQAAPAAGGFFKPQVGGFQGNRDRNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYQ1</accession>
    <name>A0A8T0GYQ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G144900</name>
        <name evidence="3" type="ORF">KC19_7G117200</name>
        <name evidence="2" type="ORF">KC19_9G176000</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9452" checksum="B3FE169FF8D4BE57" modified="2022-10-12" version="1">MALYHVLDSERSGDEIAAEVFDLVGDGGFVLIQELLKDRKELVELVHKAISILKSEKAGPGPQSRMPSYGTQVIVTSALDKKMVKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H139</accession>
    <name>A0A8T0H139_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Enoyl-CoA hydratase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G174000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H139"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06558">
        <property type="entry name" value="crotonase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941:SF54">
        <property type="entry name" value="ENOYL-COA HYDRATASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11941">
        <property type="entry name" value="ENOYL-COA HYDRATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="112" mass="11856" checksum="2767AC2D657E045D" modified="2022-10-12" version="1">MMCDIILAGERAQFGQPELNLGTIPGIGGTQRLIREVGKSRAMEMVLTGKHFMGAQEAAQRGLACRVVPGEDEALVAEAISLAKEISKQSKPVVALAKESVNTAYETGLTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H195</accession>
    <name>A0A8T0H195_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">40S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G088900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H195"/>
    <dbReference type="OrthoDB" id="186964at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000462">
        <property type="term" value="P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000007">
        <property type="entry name" value="40S ribosomal protein S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_uS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_uS9_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001749">
        <property type="entry name" value="PRK00474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569:SF16">
        <property type="entry name" value="RIBOSOMAL PROTEIN S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="RIBOSOMAL PROTEIN S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="144" mass="16374" checksum="22890A8BF49F9FB8" modified="2022-10-12" version="1">MATATESVQCFGRKKTAVAVTYCKKGRGLIKINGCPIELVEPEILRYKAFEPVLLLGRQKFAGVDMRIRVKGGGHTSQIYAIRQSIAKALVAYFQKYVDEQSKKEIKDVLLRYDRTLLVADPRRCEPKKFGGRGARSRFQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1Q2</accession>
    <name>A0A8T0H1Q2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G015400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1Q2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="76" mass="8316" checksum="8330AA470598A7DF" modified="2022-10-12" version="1">MISECRVHRIPPLSQAPARTLHYSAISPLKPEIKARSRVWKMMRDASTSTSTTAIVDATVAMSARRSAPLHATGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H261</accession>
    <name>A0A8T0H261_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Long-chain-fatty-acid--CoA ligase</fullName>
            <ecNumber evidence="6 7">6.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G044800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15421"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57560"/>
            <dbReference type="ChEBI" id="CHEBI:83139"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.3" evidence="6 7"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H261"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004467">
        <property type="term" value="F:long-chain fatty acid-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd05927">
        <property type="entry name" value="LC-FACS_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045311">
        <property type="entry name" value="LC-FACS_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272:SF3">
        <property type="entry name" value="LONG CHAIN ACYL-COA SYNTHETASE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43272">
        <property type="entry name" value="LONG-CHAIN-FATTY-ACID--COA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="8">
        <location>
            <begin position="58"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00026121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU369030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="702" mass="76671" checksum="5829ED0E6F0C16C9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H2B7</accession>
    <name>A0A8T0H2B7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G032600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the lin-54 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H2B7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005172">
        <property type="entry name" value="CRC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033467">
        <property type="entry name" value="Tesmin/TSO1-like_CXC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044522">
        <property type="entry name" value="TSO1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46159:SF6">
        <property type="entry name" value="OS12G0605300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46159">
        <property type="entry name" value="PROTEIN TESMIN/TSO1-LIKE CXC 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03638">
        <property type="entry name" value="TCR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01114">
        <property type="entry name" value="CXC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51634">
        <property type="entry name" value="CRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRC" evidence="5">
        <location>
            <begin position="767"/>
            <end position="892"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="109"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="450"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="703"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="895"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1073"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1175"/>
            <end position="1249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="119"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="496"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="928"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="956"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1124"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1183"/>
            <end position="1196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1249" mass="133178" checksum="BA319F59DE08C8B6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5H1</accession>
    <name>A0A8T0H5H1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 15">Catalase</fullName>
            <ecNumber evidence="4 15">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_8G186900</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 15">
            <text>2 H2O2 = O2 + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 14">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Peroxisome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="4 15"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5H1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08154">
        <property type="entry name" value="catalase_clade_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000002">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF23">
        <property type="entry name" value="CATALASE-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 14 15" id="KW-0349">Heme</keyword>
    <keyword evidence="11 15" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="9 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 15" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="10" id="KW-0576">Peroxisome</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="17">
        <location>
            <begin position="18"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" evidence="13">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="14">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0565398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="492" mass="56963" checksum="FD66DFEA8EF67F43" modified="2022-10-12" version="1">MDPYKYRPSSQYDTPFWTTNTGAPVWNNNNSTTVGPRGPVLLEDYHLVEKLAQFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPESLRDPRGFAVKFYTREGNFDMVGNNLPVFFIRDGIKFPDMIHALKPNPKSHIQEHWRIMDFFSHIPEACNMFTFLFDDIGIPADYRHMEGFGVHTFKLITKAGKETYVKFHWKPTCGVKNLLEDEAVMVGGANHSHATQDLYDSIAAGNFPEWKLMIQTMNIADEDKFDFDPLDDTKIWPEDMFPLQPVGRMVLNRNIDNFFAENEQLAFCPGVIVPGIYYSDDKMFQTRVFSYSDSQRHRLGPNYLMLPVNAPKCAHHNNHHEGFMNFMHRDEEVNYFPSRFDPVRHSERVPISQSRISGVREKACIHKENNFQQPGVRFRSWDPARQDRFIKRIVEMLSDPRVTPEIRSVWLSYWSQCDKTLGQRMASSLSMKSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5N8</accession>
    <name>A0A8T0H5N8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G108900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5N8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13497" checksum="E0419DFE7565414C" modified="2022-10-12" version="1">MYALRQPGLNATAPAAHLAPLGVTSVHLKDGLRCGNSELLKYWASSSANFLLMCTAVLQGLHDTCCKHAPWLLILLAGIYDEPLEHSSSRGVKFVSFSADPQIIEYRRYYFGNLADAYWAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6C7</accession>
    <name>A0A8T0H6C7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G050900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6C7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0566267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="46" mass="4933" checksum="E5ED164C9F907FF3" modified="2022-10-12" version="1">MAFLFSIAREVGDSGAGVQPFPRSTSGLLCSCPTQCTARVENRWNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H775</accession>
    <name>A0A8T0H775_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7733 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G109100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H775"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056635">
        <property type="entry name" value="DUF7733"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33829:SF2">
        <property type="entry name" value="OS04G0386700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33829">
        <property type="entry name" value="OSJNBA0044M19.10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24867">
        <property type="entry name" value="DUF7733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7733" evidence="2">
        <location>
            <begin position="45"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="274" mass="30454" checksum="26820E45E801B9C6" modified="2022-10-12" version="1">MAEVLPAGDKIRDYDSRVDPDAPAHVAQAEAEKRQKSHSVLGYFSLVQIHVITLVLVLSSSGLVPVLDLAFAGLTTVYMVFLNSTIFKPVTKGTPPDVMGKKGLVQKYTLFTALVGLLLPSGYILGGFVHGDQKALKAAAPHLFLLGCQILTENVAFRHDGVSLPIRALVPIFYNVRRLFTIMDWVKVDMNKGYESLGMHGAETGPFSPEQWLKFGKYLALSNMIVWTFNLFFFLLPVFLPRTFRKYYEMEFSAGESRAKDAQDPAKVDPSTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H794</accession>
    <name>A0A8T0H794_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Probable voltage-gated potassium channel subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">K(+) channel subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_7G035100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Forms heteromultimeric complexes with potassium channel alpha subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H794"/>
    <dbReference type="OrthoDB" id="2310150at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034702">
        <property type="term" value="C:monoatomic ion channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034220">
        <property type="term" value="P:monoatomic ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19143">
        <property type="entry name" value="AKR_AKR6C1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.100:FF:000042">
        <property type="entry name" value="Probable voltage-gated potassium channel subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150:SF2">
        <property type="entry name" value="HYPERKINETIC, ISOFORM M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <keyword evidence="5" id="KW-0851">Voltage-gated channel</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="14">
        <location>
            <begin position="85"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00053235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00062282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00067572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00077856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0566058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="394" mass="43831" checksum="A0D2F93327BD5F6F" modified="2022-10-12" version="1">MDCIHRRSDINEVLLGLSAHVSSEFPTCHLHHRSCEPIIRLFLSLQSSHCRPFFESDNLAGGCLSGVAAMEYRNLGRTGLRVSTLSYGAWVTFGNQLDVKDAVGILSRCREAGVNFFDNAEVYADGKAEEIMGAAIKQAGWKRSDLVISTKIFWGGSGPNDKGLSRKHIIEGTKASLKRLDMDYVDLLYCHRPDPNTPIEETVRAMNWVIDHGYAFYWGTSEWSGQQITEAWEIANRLDMVGPAMEQPEYNMFSRNKVESEYAPLYEKYGLGLTTWSPLASGVLTGKYSIDNIPEGSRMALANYKGLKEKSLVEATLKKVEGLKAIAKELDVPLAQMALAWVAKNPHVSSVITGATKEHQVVENMKALEVIPKLTPEVMEKIEQVVQSRPVAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8I3</accession>
    <name>A0A8T0H8I3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase 61 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G070900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8I3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049625">
        <property type="entry name" value="Glyco_transf_61_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007657">
        <property type="entry name" value="Glycosyltransferase_61"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20961:SF115">
        <property type="entry name" value="GLYCOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04577">
        <property type="entry name" value="Glyco_transf_61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyltransferase 61 catalytic" evidence="5">
        <location>
            <begin position="332"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="516"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="516"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="536" mass="61375" checksum="724A07AA7572CDB1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCE3</accession>
    <name>A0A8T0HCE3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cytochrome c-type biogenesis protein H TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G090800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCE3"/>
    <dbReference type="OrthoDB" id="421121at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056413">
        <property type="entry name" value="TPR_CcmH_CycH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050498">
        <property type="entry name" value="Ycf3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858:SF17">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44858">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23914">
        <property type="entry name" value="TPR_CcmH_CycH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50293">
        <property type="entry name" value="TPR_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c-type biogenesis protein H TPR" evidence="4">
        <location>
            <begin position="214"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="221"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF23914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0569441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="351" mass="38510" checksum="D1E1382F4622DD6D" modified="2022-10-12" version="1">MMALSRQLSSLVITNAPLPWPSSSLAPLPTMAMTHLNAIQCRASGAPNSQVHAAIQAKSVTRRQALLAGGLVPAFLQLSFPSATPAAVTPATIDLSKVPSRAFDAGDARLREAANLFQEALNATTVEEEEKLWTQVIEKYGGLDAEWVSDIVSRAWGNRGNSRSRQGKMEEALADFDRSIALAPYAADPVLNRGVTLESLGRYEEAAADYQAVLLAQPNDPAAWNNLGNVKAALGQYDEALSNYRRAVQLAPEFSFAAANYALILYQVGKENEAFKQFRSLLRRYPEFPDVRAALAVALYAQGLTAEAETNWGRLEDGRYRDRNWVRYTRKWPPRLVKALEGFLDVKAVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCX6</accession>
    <name>A0A8T0HCX6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Vacuolar protein sorting-associated protein 41 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G178400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for vacuolar assembly and vacuolar traffic.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Late endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the VPS41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCX6"/>
    <dbReference type="OrthoDB" id="244107at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030136">
        <property type="term" value="C:clathrin-coated vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030897">
        <property type="term" value="C:HOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005770">
        <property type="term" value="C:late endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009267">
        <property type="term" value="P:cellular response to starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034058">
        <property type="term" value="P:endosomal vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016236">
        <property type="term" value="P:macroautophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006623">
        <property type="term" value="P:protein targeting to vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16687">
        <property type="entry name" value="RING-H2_Vps8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057780">
        <property type="entry name" value="Beta-prop_Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000547">
        <property type="entry name" value="Clathrin_H-chain/VPS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016902">
        <property type="entry name" value="Vps41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045111">
        <property type="entry name" value="Vps41/Vps8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057779">
        <property type="entry name" value="Znf_RING_Vps41"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12616:SF1">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23411">
        <property type="entry name" value="Beta-prop_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23556">
        <property type="entry name" value="TPR_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23555">
        <property type="entry name" value="zf-RING_Vps41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028921">
        <property type="entry name" value="VPS41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00299">
        <property type="entry name" value="CLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50236">
        <property type="entry name" value="CHCR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0813">Transport</keyword>
    <keyword evidence="8" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="115"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="repeat" description="CHCR" evidence="9">
        <location>
            <begin position="627"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="11">
        <location>
            <begin position="898"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="851"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="936"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="936"/>
            <end position="954"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR028921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0567999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1007" mass="111440" checksum="55BB7C7925F01232" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE81</accession>
    <name>A0A8T0HE81_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G056000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0568967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="210" mass="23416" checksum="4589F3DCD43B98A0" modified="2022-10-12" version="1">MDSHHHRHPKRESVMKRKRRDSKRSKHRYESSSDAAAPSSSASSSSSSSSESSDSDSGSSQSGSSSDDHRSRRSSKRNHHHPNDHHPRRCEFFQIFLGLCFAISSAGEVLALVCHLVYSSWLFSFGFRGTRAQATMTLMTPNGPGNTDGKILRRRGRRQETFHSTAMGAQCWSSSPDCGDLQRCSRGLCSTHSSNLILIDEQCSKYELHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEP7</accession>
    <name>A0A8T0HEP7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G114600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000712">
        <property type="term" value="P:resolution of meiotic recombination intermediates"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000819">
        <property type="term" value="P:sister chromatid segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.670:FF:000001">
        <property type="entry name" value="DNA topoisomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050634">
        <property type="entry name" value="DNA_Topoisomerase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169:SF38">
        <property type="entry name" value="DNA TOPOISOMERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10169">
        <property type="entry name" value="DNA TOPOISOMERASE/GYRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00418">
        <property type="entry name" value="TPI2FAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="9">
        <location>
            <begin position="8"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="86" mass="9857" checksum="CFE1671655473477" modified="2022-10-12" version="1">MSGISVVGRDKYGVFPLRGKLLNVREASHKQIMDNAEISNIKRILRLQHGEDYDSTKSLRHGHVMIMTDQDHDGFHIKGLLMCFIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HF78</accession>
    <name>A0A8T0HF78_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G150900</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the syntaxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HF78"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006887">
        <property type="term" value="P:exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048278">
        <property type="term" value="P:vesicle docking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15848">
        <property type="entry name" value="SNARE_syntaxin1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00179">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.70:FF:000003">
        <property type="entry name" value="Qa-SNARE, Sso1/Syntaxin1-type, SYP12A-group"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000008">
        <property type="entry name" value="Syntaxin 132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045242">
        <property type="entry name" value="Syntaxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006012">
        <property type="entry name" value="Syntaxin/epimorphin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006011">
        <property type="entry name" value="Syntaxin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19957:SF416">
        <property type="entry name" value="T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05739">
        <property type="entry name" value="SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00804">
        <property type="entry name" value="Syntaxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00503">
        <property type="entry name" value="SynN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00914">
        <property type="entry name" value="SYNTAXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="6">
        <location>
            <begin position="213"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0570283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="311" mass="35275" checksum="B788EA4F3C84916F" modified="2022-10-12" version="1">MNSLLNNTVGKARNYVDLKKDARRGDVEMGEAPMGDGGGEVDMTQFFDEVGVIKSEMDRIKQLLEKVQAANDESRTVHKAQEMKALRSRMDSDIAQVTKLAKSIKLKLEVLDRANAANRRVRGCEEGSPTDRTRTSITSTLRKKLKDLMGEFQVLRQRMMEEYKETVERRYYTVTGEHADDDTIENIIETGNSETFLQKAIQEQGRGQVLDTIKEIQERHDAVKEIERNLIELNQIFMDMATLVEAQGEQLNDIEQQVNKASSFVARGTTQLKVAKDHQRAKRKWVCMGIALIIILILIVLLPILRSLGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG62</accession>
    <name>A0A8T0HG62_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G102800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035905179" evidence="1">
        <location>
            <begin position="22"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6417" checksum="846C305AEDB4883C" modified="2022-10-12" version="1">MIPVVSLFSLFFLSPFSVEYSRILYDPQILLCMRVPCEVYFSVKIYFVILCTLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIU9</accession>
    <name>A0A8T0HIU9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Mg-protoporphyrin IX chelatase</fullName>
            <ecNumber evidence="10">6.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G130000</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 10">
            <text>protoporphyrin IX + Mg(2+) + ATP + H2O = Mg-protoporphyrin IX + ADP + phosphate + 3 H(+)</text>
            <dbReference type="Rhea" id="RHEA:13961"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60492"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.6.1.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Redox regulation; active in reducing conditions, inactive in oxidizing conditions.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Porphyrin-containing compound metabolism; chlorophyll biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD and CHLH.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">The magnesium chelatase complex is a heterotrimer consisting of subunits CHLI, CHLD, AND CHLH.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Plastid</location>
            <location evidence="10">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.6.1.1" evidence="10"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010007">
        <property type="term" value="C:magnesium chelatase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016851">
        <property type="term" value="F:magnesium chelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015995">
        <property type="term" value="P:chlorophyll biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.80:FF:000001">
        <property type="entry name" value="Mg-protoporphyrin IX chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000601">
        <property type="entry name" value="Mg-protoporphyrin IX chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.80">
        <property type="entry name" value="Magnesium chelatase subunit I, C-Terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011775">
        <property type="entry name" value="Mg_chelatase_ATPase-isu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02030">
        <property type="entry name" value="BchI-ChlI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF9">
        <property type="entry name" value="MAGNESIUM-CHELATASE SUBUNIT CHLI-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 10" id="KW-0149">Chlorophyll biosynthesis</keyword>
    <keyword evidence="10" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 10" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="10" id="KW-0934">Plastid</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA+ ATPase" evidence="11">
        <location>
            <begin position="117"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0569982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="433" mass="46558" checksum="2F49D2BB3C968AE0" modified="2022-10-12" version="1">MAMLVRGAGAVVAAVGVSSSSGGKQVQSGSSGVLACRASSFCQGVSGRLSCAGFQTLERRAGGPLRVVNVATPVKEQGSSTENVASKENARPVFPFTAIVGQEEMKMCLILNVIDPKIGGVMIMGDRGTGKSTTVRALVDLLPEIKVVAGDPFNSSPEDPELMSEDVRKRVQAKEKLSVTTSRINMVDLPLGATEDRVCGTIDIEKALTEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISISHPARFILIGSGNPEEGELRPQLLDRFGMHAQVGTVKDPELRVKIVEERGMFDANPKSFRVNYEGSQLELRDQIDNARALLPNVKVPHDLRVKISQVCSELDVDGLRGDIVSNRAAKALAAFRGRDEVTPEDIGSVMPNCLRHRLRKDPLESIDSGTLVVDKFNEVFGYSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJI1</accession>
    <name>A0A8T0HJI1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G199700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJI1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0570945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="378" mass="43368" checksum="62358C62976299FC" modified="2022-10-12" version="1">MDCAPDESNAWALRYLGAFVDVRGHDSVPCFYSCNISQSAACGQPSFTVSLSRRGNEWGYETFNVKAVNFLKAIRLLVACPTLTEVHFSYSNMAYWEDYWTRNSVLPWSEDLMSEVFTLLRSTPSLSCFHFSSSLTYESINCKHLQSLVCENPRLETLTVSASGSGFVVLAEAIAVCLSRNTVLKSFTLRISTYKYGLNQESLEILFRPFTSSSPSDANVHLKELALYLQNPDGYWVDAIANLVCRNTTLKKLDLRFRKLSSGLKHSWRELRALASALQSNTTLKHVQCIYGWDHYVNYPPDDVKYITDKNFWQEVFQIQEILRTMIDNELRMNTSLESFAVEHWTLLRVGTEWQMSYRGPCLREQTNEYNVKVKMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK19</accession>
    <name>A0A8T0HK19_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_6G214500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK19"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000034">
        <property type="entry name" value="Kinase suppressor of Ras 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF271">
        <property type="entry name" value="ATMRK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000654">
        <property type="entry name" value="Integrin-linked_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="85"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0571146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="43448" checksum="E8EC285307070C76" modified="2022-10-12" version="1">MEGSSGNPETGVRTEGNVKVTTGGGDSALHKKNSMVRADLVNLADVDAALERHLNRAQSKPAPSAEQAADPPGPAEEWEINPREITLKNIIARGTFGTVHKGVYKGQDVAVKLLEWGEENTMKKSEVQYYRNQFRQEVAVWHKLDHPNVTKFIGASMGNSDLRIPSAVDGDDGFHHVPNNACCVVVEYLAGGTLKDYLIRNRRKKLSYKVVVELALDVSRGLAYLHSQKIAHRDVKTENMLLDKQRRVKIADFGVARVEASNPKDMTGDTGTPGYMAPEILDGKPYNKKCDVYSFGICLWEVYCCDMPYMTLSFADMTSAVVHQNLRPEMPKCCPNGLADIMRKCWDANPEKRPQMSDVVRMLEALDTSKGGGMIPDGAQPHGCFCFGKYKGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKC8</accession>
    <name>A0A8T0HKC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G224400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="161" mass="17901" checksum="292831ECA0414D1B" modified="2022-10-12" version="1">MVWPWAGHGKVQVLPRQSPSLSWEDGGAHATEVCVKTEKTERDAEFEIWRSFETSWVLEGRRPLRDWRRRGRLPLWRALTATPAALWAAAAATTPAAGALASASTTITGGLSTHDHHPRRRELLQIFLGFCFAISSAGEFPAKSNHPCLLGLDFLVWISRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL17</accession>
    <name>A0A8T0HL17_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG016300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL17"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="159" mass="16821" checksum="C7608E635A90F500" modified="2022-10-12" version="1">MSFPSSASPSPWAWAKSCFPAARRAAIACGSEAFSASFFRAACRALSNDFCKISSSSAPTMISSVSSTSMALASLSSFKILEASAALATALSYRSRRASADAFISSCIIDLREMVSRDPRSVVPRPSATASASRASKSSLSFLRSFFFFFGFLNVVISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL83</accession>
    <name>A0A8T0HL83_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG021500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL83"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="16285" checksum="57498F427FF9A03F" modified="2022-10-12" version="1">MFPPPSVLIVNFDPSLSFLCCANATSAPRCSALRFDSRLSISQETEELDSSDANTEYMFRSSRFMSHASAGQENTGVSGGAKKGESILGRLDLGRPVDALPRFSSPTESALSWLEGDTYGLLAGCCGGCVCLVCGPRPLYMSSCRCPIAASKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLB6</accession>
    <name>A0A8T0HLB6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG027000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11746" checksum="48F6D00DD8AA57D7" modified="2022-10-12" version="1">MRLLTPLQKWQYEMGLPVEGVWNSRRWAEGVGLVSRCKDESTLTKKPRVRQDEEPSKFGGRSSINPVHEEDMNESLSEEEDEADDDGEVKNSLPSRKGKNQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ14</accession>
    <name>A0A8T0HQ14_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG144300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15754" checksum="C72554DA6FA75054" modified="2022-10-12" version="1">MTRGGSAAARRGRWLHVRKSPENADDLRPWLAEVDRARRRGMDIPPLRAIAPILQVDADFRWTIACALELLDIIAASGISYPLNTSVNTSVNSEVDSNSVVQSEDSVSTDSESVSAHRYHLCQPYSYARYSAMNQRHRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSE9</accession>
    <name>A0A8T0HSE9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG198500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSE9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035801063" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="85" mass="9801" checksum="102ACE2D29B2DFC1" modified="2022-10-12" version="1">MYWVWIWLILLWRHRIRAARLWQQGLCRECSGGGLGADEMCTSSCIVKPVVGLEKPNMITMIDALLKVSKLFGLYENVQFGRNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSX7</accession>
    <name>A0A8T0HSX7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG194900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSX7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="166" mass="18789" checksum="CDDE003A67A4D984" modified="2022-10-12" version="1">MKKSDVQAAALACFESMGIPLANRFREPVSTLVHPQTRNWLGFLKVDLLNPSTDGIALLKGYKFFTLQLQDLTYTIEKVEKGFDFLSTATNHRLKLQSPILARYTSRQLLGELPRLKYLAGINLKFIGITKRTKEMETTEITVASNLTKRYLLDTPILFAGHCLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT37</accession>
    <name>A0A8T0HT37_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG221800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14863" checksum="F89D1F649182B00D" modified="2022-10-12" version="1">MAPKRRYKHYAEVVRRSMRLANHDNLPSTSSEVPPITPTIESTPPPPPLHWPPKLLHTPQSLRRKRRTHITGEDGRPKDNAEGHDNTQGEGGARSGAGGKGTSCEQSAGAEGSNMHVEGWAEEEGLDRLFGEKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWE2</accession>
    <name>A0A8T0HWE2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Trafficking protein particle complex subunit 8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG286600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990072">
        <property type="term" value="C:TRAPPIII protein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058541">
        <property type="entry name" value="Ig_TPPC8_1st"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058538">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057651">
        <property type="entry name" value="Ig_TPPC8_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024420">
        <property type="entry name" value="TRAPP_III_complex_Trs85"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975:SF6">
        <property type="entry name" value="TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12975">
        <property type="entry name" value="TRANSPORT PROTEIN TRAPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24545">
        <property type="entry name" value="Ig_TPPC8_1st"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24544">
        <property type="entry name" value="Ig_TPPC8_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24542">
        <property type="entry name" value="Ig_TPPC8_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12739">
        <property type="entry name" value="TRAPPC-Trs85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPPC8 first Ig-like" evidence="4">
        <location>
            <begin position="625"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 second Ig-like" evidence="3">
        <location>
            <begin position="846"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="domain" description="TPPC8 C-terminal Ig-like" evidence="2">
        <location>
            <begin position="1196"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="704"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF24544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF24545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0574738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1403" mass="155633" checksum="F9FBCD9D447E37A6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ80</accession>
    <name>A0A8T0HZ80_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isovaleryl-CoA dehydrogenase, mitochondrial</fullName>
            <ecNumber evidence="5">1.3.8.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_5G054500</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>3-methylbutanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 3-methylbut-2-enoyl-CoA + reduced [electron-transfer flavoprotein]</text>
            <dbReference type="Rhea" id="RHEA:12276"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57344"/>
            <dbReference type="ChEBI" id="CHEBI:57345"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="1.3.8.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-leucine degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.8.4" evidence="5"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ80"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008470">
        <property type="term" value="F:3-methylbutanoyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006552">
        <property type="term" value="P:L-leucine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01156">
        <property type="entry name" value="IVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.540.10:FF:000007">
        <property type="entry name" value="Isovaleryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.10:FF:000003">
        <property type="entry name" value="isovaleryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.110.10:FF:000004">
        <property type="entry name" value="Isovaleryl-CoA dehydrogenase, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="entry name" value="Acyl-CoA dehydrogenase/oxidase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.10">
        <property type="entry name" value="Butyryl-CoA Dehydrogenase, subunit A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034183">
        <property type="entry name" value="IVD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884">
        <property type="entry name" value="ACYL-COA DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43884:SF12">
        <property type="entry name" value="ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016578">
        <property type="entry name" value="HsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="Acyl-CoA dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="Acyl-CoA dehydrogenase NM domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 15 16" id="KW-0274">FAD</keyword>
    <keyword evidence="7 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="10 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase N-terminal" evidence="19">
        <location>
            <begin position="60"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA oxidase/dehydrogenase middle" evidence="18">
        <location>
            <begin position="177"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA dehydrogenase/oxidase C-terminal" evidence="17">
        <location>
            <begin position="284"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="13">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="178"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="295"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="391"/>
            <end position="395"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="418"/>
            <end position="419"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="420"/>
            <end position="422"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00052875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR634183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0576087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="436" mass="47603" checksum="DADACD7792D0BDED" modified="2022-10-12" version="1">MRRQGANLAGRLWNLVDKKTWPRAHSKFVSPACFSSRRMSTSTAFVEEGASGGRSLLLDDTAEQFKESVRQFAQENIAPHAAAIDHNNNFPTDVNLWKLMGDFNLHGITVPEEFGGLGLGYLYHCIAMEEISRASGSVALSYGAHSNLCINQLVRNGTQAQKEKYLPKLISGEHIGALAMSEPNSGSDVVSMKCRAEKTEGGYIFNGNKMWCTNGPKASTLIVYAKTDTNAGAHGITAFIIEKGMEGFSTAQKLDKLGMRGSDTCELVFDNCFVSNDQILGQEGKGVYVMMSGLDLERLVLAAGPLGLMQACLDVVLPYVHERQQFGKPIGEFQLMQGKLADMYTKMQASRAFVYSVARMCDAGHADRKDCAAVILFAAENATQMALQAIQCLGGNGYVNEYPTGRLLRDAKLYEIGAGTSEIRRMLIGRELFKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZH9</accession>
    <name>A0A8T0HZH9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G052200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZH9"/>
    <dbReference type="OrthoDB" id="69150at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37736">
        <property type="entry name" value="GLYCINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37736:SF1">
        <property type="entry name" value="GLYCINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="541"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="437"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="488"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="569"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="586" mass="62576" checksum="61AFD67267F5C0ED" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0V7</accession>
    <name>A0A8T0I0V7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G090100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the plant acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0V7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="entry name" value="Chloramphenicol acetyltransferase-like domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050317">
        <property type="entry name" value="Plant_Fungal_Acyltransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642:SF323">
        <property type="entry name" value="BAHD FAMILY ACYLTRANSFERASE, CLADE V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31642">
        <property type="entry name" value="TRICHOTHECENE 3-O-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02458">
        <property type="entry name" value="Transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="439" mass="49215" checksum="DE36CAC4725A5F23" modified="2022-10-12" version="1">MKLIRRDVSTVYPSEPCEPHVMYMSGADHIVRPRHLPLLVFYKAREDGEEVMPTQLLKNSLSSLLSKFYPAAGRLRRRSSDRKLELLCNNAGVEFVEATVDGTLNEFDGFTPNKFYTELLDPVPVGFGEAFTEFPITYIQVTRFACGGVSLVTTINHACTDGLSVNQFLTSWSEVARGLEMSNPPFHDRTLLKLQTSPNPDFHPKELRSLVSVQQVTPNGDLTSWPTERMFLFTPEQLRRVKKLAVGAGEHGTFTTFEAINAHVWRSVTKARNLPANTPTKFLTTLDMRKRLKPNLPEGYFGNAICFVSASSTSHDIVQNALSYSANVIREAIHGFSESYYRNFLAFAQSHPHPLVMNVNWADSAGHDVSVSSWARMGFMNLDFGSGNPVFCGPGNNPFEGSIFMLPTDKGDGFLNIFVSLKPQHMKNLESDKEFFLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0X5</accession>
    <name>A0A8T0I0X5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">SWI/SNF complex subunit SWI3D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_5G131500</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0X5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02336">
        <property type="entry name" value="ZZ_RSC8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000020">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000014">
        <property type="entry name" value="SWI/SNF complex subunit SMARCC2 isoform C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041984">
        <property type="entry name" value="Rsc8/Ssr1/Ssr2_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032451">
        <property type="entry name" value="SMARCC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802:SF41">
        <property type="entry name" value="BRAHMA ASSOCIATED PROTEIN 155 KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12802">
        <property type="entry name" value="SWI/SNF COMPLEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04433">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16495">
        <property type="entry name" value="SWIRM-assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00569">
        <property type="entry name" value="ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIRM" evidence="13">
        <location>
            <begin position="203"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ZZ-type" evidence="12">
        <location>
            <begin position="363"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="15">
        <location>
            <begin position="417"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="11">
        <location>
            <begin position="417"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="14">
        <location>
            <begin position="425"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="25"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="473"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="602"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="771"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="897"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="704"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="122"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="602"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="646"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0577112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="926" mass="98456" checksum="EE269015601D3209" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I289</accession>
    <name>A0A8T0I289_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_5G127300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I289"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04216">
        <property type="entry name" value="Phytocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000034">
        <property type="entry name" value="Cupredoxin superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039391">
        <property type="entry name" value="Phytocyanin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003245">
        <property type="entry name" value="Phytocyanin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021">
        <property type="entry name" value="BLUE COPPER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021:SF193">
        <property type="entry name" value="OS06G0218600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02298">
        <property type="entry name" value="Cu_bind_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51485">
        <property type="entry name" value="PHYTOCYANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035904664" description="Phytocyanin domain-containing protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Phytocyanin" evidence="5">
        <location>
            <begin position="28"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="131"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="190"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="190"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="234"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0577045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="342" mass="35961" checksum="26D152737E20881A" modified="2022-10-12" version="1">MLEVLVNLALNFVLIILPVSHVRVVMAENYIVGGAAGWGFVPTASYYSDWATGINFVPGDKLNFRYDPTEHNVQQVSLSDFASCNTLNPMLQYQSGDDLIPLPQAGNYYFICGFAEHCDGGGMLMKVTVAATGSTPPPPHHPPPPPTHPPPPSNPPPPPPNHPPPPPNHPPPPPNHPPPPPNYPPPPLYPPPPPSHPPPPPPNHSPPPPTPVPQPPPPPLQSPPPPDLVDKYKPPPPPPTLNPSPPSPPPPPPLAPPTSPPPPSTLTPSPPPPDNLNQNQTMSNSPDAPPPPPPISTDVPPAPSNDTLAPSPSDDDPDAAHALHSGMDLLFTVLVIVAAVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I364</accession>
    <name>A0A8T0I364_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">mRNA guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.50</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_5G191200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-ribonucleoside in mRNA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:67012"/>
            <dbReference type="Rhea" id="RHEA-COMP:17165"/>
            <dbReference type="Rhea" id="RHEA-COMP:17166"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:167616"/>
            <dbReference type="ChEBI" id="CHEBI:167617"/>
            <dbReference type="EC" id="2.7.7.50"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:67013"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.50" evidence="2"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I364"/>
    <dbReference type="OrthoDB" id="200924at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140818">
        <property type="term" value="F:mRNA 5'-triphosphate monophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004484">
        <property type="term" value="F:mRNA guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004721">
        <property type="term" value="F:phosphoprotein phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006370">
        <property type="term" value="P:7-methylguanosine mRNA capping"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07895">
        <property type="entry name" value="Adenylation_mRNA_capping"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14502">
        <property type="entry name" value="RNA_5'-triphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.190.10:FF:000055">
        <property type="entry name" value="mRNA capping enzyme family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.470.30:FF:000005">
        <property type="entry name" value="mRNA capping enzyme, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000689">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.30">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017074">
        <property type="entry name" value="mRNA_cap_enz_bifunc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001339">
        <property type="entry name" value="mRNA_cap_enzyme_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013846">
        <property type="entry name" value="mRNA_cap_enzyme_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051029">
        <property type="entry name" value="mRNA_Capping_Enz/RNA_Phosphat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10367:SF17">
        <property type="entry name" value="MRNA-CAPPING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03919">
        <property type="entry name" value="mRNA_cap_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01331">
        <property type="entry name" value="mRNA_cap_enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036958">
        <property type="entry name" value="mRNA_capping_HCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56091">
        <property type="entry name" value="DNA ligase/mRNA capping enzyme, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10 15" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0506">mRNA capping</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="17">
        <location>
            <begin position="170"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="16">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="16">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphocysteine intermediate" evidence="13">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="active site" description="N6-GMP-lysine intermediate" evidence="14">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="423"/>
            <end position="425"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="542"/>
            <end position="544"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="613"/>
            <end position="618"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00044624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR036958-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR036958-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR036958-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0577910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="675" mass="78491" checksum="2E6A640554276AB3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3X7</accession>
    <name>A0A8T0I3X7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G182600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3X7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0577796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="92" mass="10457" checksum="BDD35166546E5B15" modified="2022-10-12" version="1">MHEAPASALRKGGPSKVVSRALVWPFTDWTMSSFFSPEGIQVEAPVFNDFHGFPLRLVPSCALRRISGIYLWWIASLHFHSFKPFLSSTQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I424</accession>
    <name>A0A8T0I424_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G172100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I424"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580:SF28">
        <property type="entry name" value="BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="24"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="715"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="742"/>
            <end position="752"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="760" mass="80587" checksum="DF452DCAD230366F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4B2</accession>
    <name>A0A8T0I4B2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Alpha-glucosidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G179900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4B2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="entry name" value="Golgi alpha-mannosidase II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048395">
        <property type="entry name" value="Glyco_hydro_31_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762">
        <property type="entry name" value="ALPHA-GLUCOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22762:SF120">
        <property type="entry name" value="HETEROGLYCAN GLUCOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21365">
        <property type="entry name" value="Glyco_hydro_31_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51011">
        <property type="entry name" value="Glycosyl hydrolase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoside hydrolase family 31 TIM barrel" evidence="5">
        <location>
            <begin position="33"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl hydrolase family 31 C-terminal" evidence="7">
        <location>
            <begin position="309"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="6">
        <location>
            <begin position="403"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF21365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="794" mass="89200" checksum="9E0D2FB89AB3FD4B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I665</accession>
    <name>A0A8T0I665_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G190500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I665"/>
    <dbReference type="OrthoDB" id="508070at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031432">
        <property type="entry name" value="MGP1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36013">
        <property type="entry name" value="ATP SYNTHASE 24 KDA SUBUNIT, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36013:SF2">
        <property type="entry name" value="ATP SYNTHASE 24 KDA SUBUNIT, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15704">
        <property type="entry name" value="Mt_ATP_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="159"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="231" mass="26518" checksum="A208403AAA219E9B" modified="2022-10-12" version="1">MAALTRRSAAFLRSVRAMKPERSATCRFLSAAPKADDDIVKKVFIRQQKNFRTYLEEISKSKFDMDHNNENHVKAYQEMQARIRENLGHPSFTQKIADLLDAAADDAPDVRTILMNSRTLRNEAGIEDDMGADDMMLQALNRLEKSIGKPLTRDDANGMSQWKKEIDQINAKLKIKDEDLEKLEEEAEYAAAKAQLEEFRNVAFDKIDSIKRRDNLKVDVTIGDIDHRNYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I761</accession>
    <name>A0A8T0I761_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">plastoquinol--plastocyanin reductase</fullName>
            <ecNumber evidence="3">7.1.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_4G010100</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="20">
            <text>2 oxidized [plastocyanin] + a plastoquinol + 2 H(+)(in) = 2 reduced [plastocyanin] + a plastoquinone + 4 H(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:22148"/>
            <dbReference type="Rhea" id="RHEA-COMP:9561"/>
            <dbReference type="Rhea" id="RHEA-COMP:9562"/>
            <dbReference type="Rhea" id="RHEA-COMP:10039"/>
            <dbReference type="Rhea" id="RHEA-COMP:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17757"/>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
            <dbReference type="ChEBI" id="CHEBI:62192"/>
            <dbReference type="EC" id="7.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="19">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Rieske iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.1.6" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I761"/>
    <dbReference type="OrthoDB" id="1637982at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009496">
        <property type="term" value="F:plastoquinol--plastocyanin reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd03471">
        <property type="entry name" value="Rieske_cytochrome_b6f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.700:FF:000002">
        <property type="entry name" value="Cytochrome b6-f complex iron-sulfur subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.102.10.10:FF:000007">
        <property type="entry name" value="Cytochrome b6-f complex iron-sulfur subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.700">
        <property type="entry name" value="Single helix bin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01335">
        <property type="entry name" value="Cytb6_f_Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023960">
        <property type="entry name" value="Cyt_b6_f_Rieske"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014349">
        <property type="entry name" value="Rieske_Fe-S_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005805">
        <property type="entry name" value="Rieske_Fe-S_prot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057415">
        <property type="entry name" value="TM_PetC"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF045928">
        <property type="entry name" value="Cytb6fFeSPetC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010001">
        <property type="entry name" value="PRK13474.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10134">
        <property type="entry name" value="CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25471">
        <property type="entry name" value="TM_PetC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00162">
        <property type="entry name" value="RIESKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="12" id="KW-0249">Electron transport</keyword>
    <keyword evidence="14" id="KW-0408">Iron</keyword>
    <keyword evidence="15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="16" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="10" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Rieske" evidence="21">
        <location>
            <begin position="119"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00047828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0578263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="232" mass="24140" checksum="6E6B31AA3430615B" modified="2022-10-12" version="1">MATATVASSALASGLSSKLAAVSNGVSGGPCIVAVPNPGWSAGRKDAQGMKVVSMAAAAPERVPDMEKRNLMNLLLLGAISLPTAGLLGPYLYFLVPPGSGGSGLGVTAKDALGNDVTMSGWLKTHQPGDRTLAQGLKGDPTYLVVENDGTLATYGVNAVCTHLGCVVPWNKAENKFMCPCHGSQYNNQGKVVRGPAPLSLALAHVDVTDDKVVFSQWSETDFRTGEEPWWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8A4</accession>
    <name>A0A8T0I8A4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SIAH-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_4G133900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8A4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044286">
        <property type="entry name" value="SINL_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013010">
        <property type="entry name" value="Znf_SIAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46632:SF16">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SINA-LIKE 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46632">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE SINA-LIKE 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21361">
        <property type="entry name" value="Sina_ZnF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51081">
        <property type="entry name" value="ZF_SIAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SIAH-type" evidence="7">
        <location>
            <begin position="115"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0579910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="296" mass="33947" checksum="BCA65E25118B48E0" modified="2022-10-12" version="1">MSILESEVGEQSQTRTMDPHQDVKPFSNELRLSGERRRRSKSPESDNRRRKYDVDVGLLLCIICENELLPPVCQCKNGHMACQACCKTRTRGQCPKCFQPIGRTRNKAVEQMIASLKSPCKHAVNGCKKMLASSNRKQHELFECEFMMLYCPFQCGFSGFIRNFSSHVEHKHKDARIIRHNESEQLLTFGGFNLDSRDEYVFLKSCPELFLLHQEDTALGKMLYVTSCGKETPYSLEVLITSDYEKGRTKSFKMETMTSINGRTPGLRDFLLVPKQITCPHYPPVSTRCTVRIPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I8X5</accession>
    <name>A0A8T0I8X5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G098600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I8X5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TIR" evidence="5">
        <location>
            <begin position="175"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1159"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1173"/>
            <end position="1193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0579435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1199" mass="136289" checksum="58DBE5FDD4B85D9B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBR4</accession>
    <name>A0A8T0IBR4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G229800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBR4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038909">
        <property type="entry name" value="Effector_transcript"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35133">
        <property type="entry name" value="PROTEIN EFFECTOR OF TRANSCRIPTION 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35133:SF1">
        <property type="entry name" value="PROTEIN EFFECTOR OF TRANSCRIPTION 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19239">
        <property type="entry name" value="GIY_YIG_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="401"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="404"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="432"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="491" mass="54904" checksum="416D62230AEBF8E1" modified="2022-10-12" version="1">MGRFVFSNCSTSDDLLVQQRCGWTGAKGRLRREDCRYVKHDKLFSKWKILMGPLDSTEQINSASRKDGSCKYHTHNLPAAQFGPGVYELGVTAPSWSQVPNSKRSRTLKTEDVIPVYIGQAANIRQRLQKYGQAGAQLEHGSRPSTPHHGDNDSVKGRSPRMVQSGFRGELPNSIGSGPRLFSEVFALGSSIAFRWAHTDSKVVAEQVESELLAVFDYAWNKGTSGTRRSRDILAKLFMAWPSKNTSFRSLIFSGKRSPWLFLGRTNAVGIKVALRKPQDTTTSTFSSRNIMRCNLCFLTTVQPKRRSITMASLDVRCGAATARGMPCNAPPLRGRKRCLQHYETKPLRGLIPSSASLNPSASTTKKFNMGSIKLQSAPVETTCFLQRGFLGRELLFQTKNKTQRKEVDAKEEKPVERRRHNSLSFNTWVKGETDQRVHDSSNMKESTKGTSFQEPLLRQGSGMRSNSSKRRVQHLGSKYASACDNDSKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICF9</accession>
    <name>A0A8T0ICF9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G251400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICF9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="359"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="391" mass="42182" checksum="450BC987699A8599" modified="2022-10-12" version="1">MVASVPHYKYYPRSVSWQVASVLNPSLQNSLPTSLLSAHSREKREREGGVDADQTELKPEGKVQSPHTAYKSWQEEEEEESGHKLTLPPQYVSPGELSKAMPKYIRLKVRPETNGNGKPVPFSTSTEPVKPGNSPALSPHYDLAAGSPRSQESSGRETPRSVLDFPQNTSTTSKLPQPAAKAASGAASPASPARSLLHTPPPITTKPSCETTPPVSAGYQNTPLSSAELRRQKTNPSGALSPRIRSAATSPMPPIPTLGSKVTDAAPASATLLRSKLNTLAQYPELMPRVVQMESTAQGSPLSPAIPVDASRPVRNRLPTPPVALPPTPPIGSRPGSRLRRVRNPHPPEPTLETYKKASPNTHATNTVWNDRRDTSREQTNPRQSILIKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICJ9</accession>
    <name>A0A8T0ICJ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G153100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8204" checksum="D1852557D496C557" modified="2022-10-12" version="1">MTSREGSVAAESFRTIRTSWCTSGKSSAYLLHNCQASRDSPEITPFTSRHCLAKRLSPHLQTHLNTKFPIHAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICM1</accession>
    <name>A0A8T0ICM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G195000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178:SF6">
        <property type="entry name" value="FAD-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47178">
        <property type="entry name" value="MONOOXYGENASE, FAD-BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding" evidence="5">
        <location>
            <begin position="9"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0580735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="404" mass="44131" checksum="2EDC506FD577A505" modified="2022-10-12" version="1">MDMGRPGTILVIGGGLGGLAFAQILRHSPVADTYKVRIFERDATPTHRGQGYMIAINNAGFSSISTIPHIASVLNEIKSKDYMANLLDGDLNIRMQLKHAPGAHGIAGLVNRWKLRTALAEGLEIEWGKRFVRYEEFETYVVAHFDDGSEVRGDLLIGADGAKSRVREQRCPALQLRQMPVLNTAGSVAVTPSVRERFPTIVQLTEKAHVNRALAAGGHSAMWMEFESQDGTPCLLWAFSFPATINSDESKDPLELKQAIDSHATHLGKELASFIQGTPVDDYIVEATHYLRAVVPVEGNPMGRTSRVTLLGDAAHAMTTHKGLGANTAFADSADLAQALTHVEAPWPALAEYEEKMIKRGFEAIKQSNQGSDTKHAVGVKSVLRNLVIRVLGWLLWTKHALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID94</accession>
    <name>A0A8T0ID94_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G207100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID94"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13028" checksum="4005E19EF237487E" modified="2022-10-12" version="1">MVHGLCVDPNAVAWTRSEPAIYSLAQVPAAQSQSAPHFPPFSLASVPAAQSQSPHLPPFSLAQVPAAQSQLAPHFPVSLAIFLLWCKSLIKLYIIASMEKLLTKHDINPSIEPAVELGTSHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG81</accession>
    <name>A0A8T0IG81_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G019400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035876167" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="79" mass="9275" checksum="98FD81C89A8FDD0B" modified="2022-10-12" version="1">MHRCRIDMGYLCCTLLLVRCCGSAKYSMLFEVDGVFRRESHILLGYYTFFSVDTRTDPYNTTQVAHVYPTPCIFLHRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGV1</accession>
    <name>A0A8T0IGV1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G036900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGV1"/>
    <dbReference type="OrthoDB" id="2012753at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37250">
        <property type="entry name" value="OS05G0496000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37250:SF1">
        <property type="entry name" value="OS05G0496000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="13485" checksum="09D79DE215073D94" modified="2022-10-12" version="1">MADVPQETSRPTFVGDETETFDTRGKAAIPLDYSVGGHGVDVNMEAPISTEDLVRAGGLGARDGIAGAMPTTVDATDYEESLMDARDYEDKVGDAESGISLRPGLGAGHHPVEILGGSMVPSEDSDMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJR0</accession>
    <name>A0A8T0IJR0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G077200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJR0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34681">
        <property type="entry name" value="UVEAL AUTOANTIGEN WITH COILED-COIL/ANKYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34681:SF2">
        <property type="entry name" value="UVEAL AUTOANTIGEN WITH COILED-COIL_ANKYRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47162">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14354" checksum="DA7A51A2CEA975E5" modified="2022-10-12" version="1">MAKPGPSCAPSSSNSDSNVDESSLETLITDAWDRAEGVLQRLKDSQGELLNRVQKLKEDWQGDMDSLVNSCEQEIEGLNNVHNADVERLRIELQSRALVLKDQLNSLQQNWQLEVGQLTNISPALPGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILD1</accession>
    <name>A0A8T0ILD1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G220800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILD1"/>
    <dbReference type="OrthoDB" id="527244at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08069">
        <property type="entry name" value="MPN_RPN11_CSN5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000001">
        <property type="entry name" value="26S proteasome non-ATPase regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056263">
        <property type="entry name" value="RPN11_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23594">
        <property type="entry name" value="RPN11_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-0647">Proteasome</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="31"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0584594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="309" mass="34377" checksum="D7506FBE8A832579" modified="2022-10-12" version="1">MESRLHRIFAGGGAGGGPHPDSPLVDSSEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDEYTVRVVDVFAMPQSGTGVSVEAVDPVFQTKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALNQRAVAVVVDPIQSVKGKVVIDAFRLINPQTMMLGQEPRQTTSNIGHLNKPSIQALIHGLNRHYYSIGINYRKNELEEKMLLNLHKKKWTDGLTLQRYDEHGKTNESTVKEMLDLAIKYNKAVQEEDQLSPEKLAIANVGRQDAKKHLEEHVSNLMSSNIVQTLGTMLDTVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILM1</accession>
    <name>A0A8T0ILM1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G226800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="ATP SYNTHASE DELTA CHAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="N-terminal domain of the delta subunit of the F1F0-ATP synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0584670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="262" mass="27360" checksum="869495D573C2F6B7" modified="2022-10-12" version="1">MEALQQSVVGSKVAAAPAVVGVGATGSRVAQVKMGFVAGSGSSFKGNGALVAKVGKAVSGASSSGGSKGVVVMNRDSAAGGYASALAELSQANNDLEKINQDIEGLGELLNNKELYEFIVSPVVDGDKKKSILKTLAEDAKFSPTTVSFLNLMVDKKRIELIKDVVKEFEAIYNDITDTQVANVMSAVKIEKPQLALIAKKIQSLCGAKNVRIKNIVDPSLIAGFIVQYGKDGSRYIDMSVKGQLDRLASQFAAAEQAAGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IND0</accession>
    <name>A0A8T0IND0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Small ribosomal subunit protein uS7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_3G229600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IND0"/>
    <dbReference type="OrthoDB" id="10264639at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14867">
        <property type="entry name" value="uS7_Eukaryote"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.455.10:FF:000002">
        <property type="entry name" value="40S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="entry name" value="Ribosomal protein S7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_uS7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_uS7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_uS7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_uS7_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_uS7_euk/arc"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003106">
        <property type="entry name" value="PRK04027.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="RIBOSOMAL PROTEIN S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="Ribosomal protein S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Small ribosomal subunit protein uS7" evidence="5">
        <location>
            <begin position="37"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0584712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="196" mass="21792" checksum="07791838B43A833B" modified="2022-10-12" version="1">MAVAQPEVKLFGRWSFDDIEINDISLADYIAVSVDKHATFVPHTAGRYSVKRFRKAQCPIVERLTNSLMMHGRNNGKKLMAVRIVKHAMEIIHLLTDANPIQVIVDAIINSGPREDATRIGSAGVIRRQAVDISPLRRVNQAIYLLTTGARESAFRNIKTIAECLADELINAAKGSSNSYAIKKKDEIERVAKANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP41</accession>
    <name>A0A8T0IP41_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G221800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP41"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008812">
        <property type="entry name" value="Ran_GTP-bd-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010:SF2">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31010">
        <property type="entry name" value="RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN 30-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05508">
        <property type="entry name" value="Ran-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="297"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="454" mass="49976" checksum="2B0C4062F6CCEF09" modified="2022-10-12" version="1">MEVGSAAALYAGSVLVKKTFEAVAQRSLSSLFTRLHVRFRGQIESQLQVLEKELESRLQVLSLPVDMCVQYVLHGNTALQGALDMALRVINDIVSFQEELEAQTYNESIVKTSQADAVSRLKGFMTRLDSILPYLSMAVNAVSLLRVADSGLSPSRLMESSHLIRTANSRQGSVTSLRARVYKYETKLTLPRWQEKMMKCSVSLRQTSSLESNEFELSITNEEESEPGDLPTSIRIPVSDISAVGSSTLHVLGLGQHELEAVLLVDTLVPSGTSEVSKDGTASTSLQEVNHYAFQCTEDTSDVPNEVNQQDDSSDHDGDSSHDSQEGDAQELESNFGSKVYKLGMLEYALRLCMLQVKEEKEHWLLSDERIRLFFVDPRYISEPMGIIQKTRSGSGKIPSGFRTPTPGKGAPVRQSRTSAGITKVASRIPNSRTNISELFYDLRLDSPGSSGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPA8</accession>
    <name>A0A8T0IPA8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G022900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PA-phosphatase related phosphoesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPA8"/>
    <dbReference type="OrthoDB" id="10030083at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046839">
        <property type="term" value="P:phospholipid dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03390">
        <property type="entry name" value="PAP2_containing_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.144.10:FF:000001">
        <property type="entry name" value="Lipid phosphate phosphatase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.144.10">
        <property type="entry name" value="Phosphatidic acid phosphatase type 2/haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043216">
        <property type="entry name" value="PAP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="PAP2/HPO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10165:SF203">
        <property type="entry name" value="LIPID PHOSPHATE PHOSPHATASE 3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="18"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Phosphatidic acid phosphatase type 2/haloperoxidase" evidence="8">
        <location>
            <begin position="93"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0585584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="297" mass="33442" checksum="FFBFAD7E9FCD4FED" modified="2022-10-12" version="1">MEPDPKLGRLFINHWTDWFFIIVLIGLEIVCQVVTPFQRYVGATNFVTQSIKYPYKRNTVPFQAVPVIALVIPLVFISIHFCVRRNVRDLHHAILGLLTTVALTAVITDAIKDGIGRPRPHFYARCFGSTLANATYDATGNVVCILSPSLMKESYKSFPSGHTSWSFAGLGYLAMYLAGKLGVFDRQGHSWKLFPVVLPILGATFVGITRVDDYWHHWTDVCAGAAIGLLSAYFCYRQHFPSLFDDPSNVPYPHMPRRKGVAESVLPTQMEERPYDERLNLERGSSQIPMIPPQARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITM0</accession>
    <name>A0A8T0ITM0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial Rho GTPase</fullName>
            <ecNumber evidence="14">3.6.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_2G056100</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Mitochondrion outer membrane</location>
            <topology evidence="1 14">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 14">Belongs to the mitochondrial Rho GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="14"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITM0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000011">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000553">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000935">
        <property type="entry name" value="Mitochondrial Rho GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013566">
        <property type="entry name" value="EF_hand_assoc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013567">
        <property type="entry name" value="EF_hand_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021181">
        <property type="entry name" value="Miro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052266">
        <property type="entry name" value="Miro-EF-hand_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020860">
        <property type="entry name" value="MIRO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001806">
        <property type="entry name" value="Small_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46819:SF1">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08355">
        <property type="entry name" value="EF_assoc_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08356">
        <property type="entry name" value="EF_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00071">
        <property type="entry name" value="Ras"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037488">
        <property type="entry name" value="Mt_Rho_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00449">
        <property type="entry name" value="RASTRNSFRMNG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00175">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00173">
        <property type="entry name" value="RAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00174">
        <property type="entry name" value="RHO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51423">
        <property type="entry name" value="MIRO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51419">
        <property type="entry name" value="RAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 14" id="KW-0106">Calcium</keyword>
    <keyword evidence="12 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 14" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="7 14" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="6 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="17">
        <location>
            <begin position="7"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="16">
        <location>
            <begin position="310"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Miro" evidence="17">
        <location>
            <begin position="418"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR037488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0586008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="638" mass="71717" checksum="16CAAA0193B09A33" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVD3</accession>
    <name>A0A8T0IVD3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protein GPR107</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G127400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVD3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054103">
        <property type="entry name" value="CAND6-7_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053937">
        <property type="entry name" value="GOST_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009637">
        <property type="entry name" value="GPR107/GPR108-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229">
        <property type="entry name" value="LUNG SEVEN TRANSMEMBRANE RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21229:SF2">
        <property type="entry name" value="RE59932P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21904">
        <property type="entry name" value="CAND6-7_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06814">
        <property type="entry name" value="GOST_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="CAND6/7 N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="GOST seven transmembrane" evidence="7">
        <location>
            <begin position="167"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF21904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0586919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="432" mass="49158" checksum="89F859EA46015C39" modified="2022-10-12" version="1">MAGRGGVWGGVVAVVVLVSLFPAVFGEIKYLSIKDDMRAIIPFETFGFLPSGEVSVVVSNVNVKEAGADRSRMGFFLSTMEDLVPVLSNLEAQGKNCLMDSKLMHTLFTLAETEKFNYTHTVQTSNEYSLFFENCVKTEISMDVMTSMYNVEGGYKDFLAVGQTQLPRMYFVFFLANVALLGVWIYVCWAQKASVHRIHALMGLLVVLKALNMICEAEDKQYVKRTGTPHGWDVAYYIFNSLRGLLLFSVIVLIGTGWSFLKPFLQDKEKKVLMVVIPLQVFANTAYIVYDEAGPSTKDFFTWKQVFLLLDIICCCAVLFPIVWSIKHLREASRTDGKAARNLVKLTLFRQFYIVVVSYIYFTRIVVFALYTVTVYRYRWTSKFAEEAANLAFYIYTGYKFRPVSHNPYFVLDDDEEEAAALEALKDDEFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVS0</accession>
    <name>A0A8T0IVS0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pectinesterase</fullName>
            <ecNumber evidence="3">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G115700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="3"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF132">
        <property type="entry name" value="PECTINESTERASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Pectinesterase catalytic" evidence="8">
        <location>
            <begin position="64"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="395"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="396"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0586771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="47908" checksum="F6B8EAC1AF573C4C" modified="2022-10-12" version="1">MCLGVREGEHCRCCMNFVGCVICAIILSAAWIPSSGGVPVRAHQGAAGSVGRLLREDGGIQTVLVVSNDGHPDHFASVQAAVDAVPMWNYLRWVIYIKPGVYYGTVVVPEGKDYITFLGESAKRTVLTYNRKACDKKLDGSEYTILDCPTVIVDASNFLAKGITFENSSPKPDDFDYNSQAPAIRVSGDNCAFYDCVFLGWQDTLYADQGKHYYKDCRIEGNVDFILGYASAVFENCTIHSRGEGFITAQSRWCEEECLAASNSTFVTSNSAFVILRSNITGYNLATYNSTGTGLTYLGRPWREYAKVVFIDSILGEHIAPEGWVDWLTDTGPLFAHDYVYFGEFNSRGPGANSSARIGWSHRLTEEEAEAYRDVSGFLGTRNWLETPPSLEQLKESNMLQEKNWSGQEGYREKFPPRRWKRMGDRDGEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVV2</accession>
    <name>A0A8T0IVV2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Subtilisin-like protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G156500</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02120">
        <property type="entry name" value="PA_subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041469">
        <property type="entry name" value="Subtilisin-like_FN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17766">
        <property type="entry name" value="fn3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8 9" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0720">Serine protease</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035937071" description="Subtilisin-like protease" evidence="10">
        <location>
            <begin position="26"/>
            <end position="840"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="12">
        <location>
            <begin position="40"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="11">
        <location>
            <begin position="175"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease fibronectin type-III" evidence="13">
        <location>
            <begin position="738"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7 8">
        <location>
            <position position="620"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0587327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="840" mass="89145" checksum="5A7E86BAAF2BC816" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVZ5</accession>
    <name>A0A8T0IVZ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G154200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVZ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="2">
        <location>
            <begin position="149"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="511" mass="57452" checksum="FAD4E6A06C4973DB" modified="2022-10-12" version="1">MAQYTDALRRVDQVIQKLKDCSMERNEIERIMTELKADALSSDDYTDTRRDLLVVAKTVRDMLNVLKTGLEGIHVEIILKMQVAIEETNSIVDRASEEDNTRLKRTRVSTQTEPGSVCGSSSKETRVTKKEICTHSCTYHPHIVNPGIWSKLPEDLVVQVFARLPIPRIIGLRKCSEAWSAMSDSSSFKGVFAEANPKLFGLLGWDGDLDKFRVRIVDVTTNEWHGTELELPKGNGYMDALFACDGGLVCFVPEWESGPFLDSVFVCNPLTNCWKKLPDIPLGFIDPVLVQLVTEGDGDWYRVILVYREKLKVGDVQTFGTLMYDSKTGSWSKMDSGLVYGTGNTLLGDKNEPMVFDCATKRMIDLEGCPSLQDLTVLRYANMKDRVFVLHVLVNPDSPGDSTERLVISEYTWESSTSDLRKVNDYEIALRYFDSGKYVSRHDVEIFTCSGMIVLTCDNLSKKGGVRQLVSVYDLSAGQWRDLPQLIGGSGARYEKLVGVFLVELRWDVVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWC5</accession>
    <name>A0A8T0IWC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Desiccation-related protein PCC13-62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G133000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052965">
        <property type="entry name" value="Pigment-catalase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694">
        <property type="entry name" value="DESICCATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694:SF26">
        <property type="entry name" value="OS05G0151100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035940187" description="Desiccation-related protein PCC13-62" evidence="1">
        <location>
            <begin position="23"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="333" mass="35811" checksum="E891B422E811F8D1" modified="2022-10-12" version="1">MGSLKGLSFGVCLVLLVGVAAAAVNGGLQIGGLDIEYKCEEGHETAVMDKELAQVALNLEYFEAEYFLWGSVGYGLDKEAPHLADGGPAPIGAQQANLDEYYKDIFYQMGLQEVGHLRAIKSALGDAPSCAFPRTQLDISKKTWAETMDKAFMAKFGKKLSPSFDPYEDSLKYLISTYTIPYVGLTGYVGANPLLKGYEAKKLVAGLLGVESGQDAVIRTEMYKIKDMKVAPYDYTVADFSEAISTLRNKASNDHVDEGLVVPKKNGAEGKVSGNILAGNKDSLAYSRTPVQVFATVYGTGDASQPGGFFPKGAQGVIAAQLRLKEGSYYEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZ79</accession>
    <name>A0A8T0IZ79_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_2G224400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZ79"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000178">
        <property type="entry name" value="serine/threonine-protein kinase PBS1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 16" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="16">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035794426" description="Protein kinase domain-containing protein" evidence="16">
        <location>
            <begin position="27"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="17">
        <location>
            <begin position="375"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0588199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="565" mass="62215" checksum="9C979934B476ECCE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0J3</accession>
    <name>A0A8T0J0J3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G022600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0J3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0589470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="134" mass="15255" checksum="A7C80C784C0D3C39" modified="2022-10-12" version="1">MVHLPDVQQYLAQCSNQSETYPNLYQIVILYNMCFTWHPYLSYYPHLEVRISRWATGVLSSSIQSYNDGQPLSADPVLFSLHSSQLKHVVSNSITGYFQHVVITHMFPSVLCSGLVIIFPAVVCKYLSHSLCLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0R3</accession>
    <name>A0A8T0J0R3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G263500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0R3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11847" checksum="9E8D2EED2FFF3DF0" modified="2022-10-12" version="1">MPSLNLNLYPLPTPPRCCIPNLPNAAASLTSIYTIISNLIAVSPLRFVPTQPHPLTTTLQIINPRPQTPQTQLHNVTTPPPSTIHRHLLLILHPESNHPQSNHLLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1H2</accession>
    <name>A0A8T0J1H2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G021200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PsbQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1H2"/>
    <dbReference type="OrthoDB" id="497707at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019898">
        <property type="term" value="C:extrinsic component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009654">
        <property type="term" value="C:photosystem II oxygen evolving complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009767">
        <property type="term" value="P:photosynthetic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.290">
        <property type="entry name" value="Oxygen-evolving enhancer protein 3 (PsbQ), four-helix up-down bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023222">
        <property type="entry name" value="PsbQ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008797">
        <property type="entry name" value="PSII_PsbQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054099">
        <property type="entry name" value="PSII_PsbQ_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33399">
        <property type="entry name" value="OXYGEN-EVOLVING ENHANCER PROTEIN 3-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33399:SF3">
        <property type="entry name" value="OXYGEN-EVOLVING ENHANCER PROTEIN 3-1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05757">
        <property type="entry name" value="PsbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101112">
        <property type="entry name" value="Oxygen-evolving enhancer protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00035649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0589445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="222" mass="23545" checksum="96E527F032EF575B" modified="2022-10-12" version="1">MANAVASMAGLSQGLKLESTLAGTKVAVGSSNSVSTVKFAPVQVRASSEETQSRRSFFSLAAVSLAATALVGNARALEAIKLEPPPAPSGGLPGTDNADQARDVDLNLKERFYLQPKTPQEAADRVKVAVKDIKDVKPLIDRKAWPYVQNGLRSTASYLRFDLNTIGASKPKEERKAFKALATKAIDAMDTLDYAARVKSPEKAAKAYAQVVASLDQVVAAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4N2</accession>
    <name>A0A8T0J4N2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Early light-induced protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G042500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ELIP/psbS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4N2"/>
    <dbReference type="OrthoDB" id="513190at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14154">
        <property type="entry name" value="UPF0041 BRAIN PROTEIN 44-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00037956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0589723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="232" mass="25119" checksum="F26DB1D3F980264E" modified="2022-10-12" version="1">MAVAMQSAVAQLGGLTALPSLTSSRKVFNANSRVVAAPRLATSLAGRVRCEAGKGLREVIDESTKKDITEDEIRKSMETNESEQRSYFGAKPTDGMEKAVGFVPRPEIERRPETGDKSFLSVFAFDGAAPEAINCRLAMLGMVWAFVAEKATGLTVVEQLFNPTTSGLVYFVGAVQLFTYASLVPIMNGESTDARSFGPFTARAERWNGRLAMLGFLSLVVTELIRGTPVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5P2</accession>
    <name>A0A8T0J5P2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G075500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5P2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26312:SF222">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26312">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="228" mass="24409" checksum="FFB0A1760F3F5A2D" modified="2022-10-12" version="1">MAVLLRTVSTCGRAATGAAARVVCGIESSKLPKSNGAFFQEQEMAFSKAKNGAGFSQSVDLPARCQAVAAVCPIPTRQSVGVLERAAPEVEKILEPETRPATLNQRAEPLPRSFLAESVSGNLVECSGLGSRPLYTNVLAEFQLSYTGTSQAEVPATVDINAVKMAYHAALERSPADARLVSEFAMFTWKAMGNVDAAEELYNKALELAPNDSNIQANHALFLWQCDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5U5</accession>
    <name>A0A8T0J5U5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G163600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5U5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035852323" evidence="2">
        <location>
            <begin position="21"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="126" mass="14023" checksum="6CF1B7A6585B2D0D" modified="2022-10-12" version="1">MLGLCIICFDTLLPAAIAMAYKFLRPSRVCSTSTQSKSPPQSKLRALQQKPNSQHTAHMVLRSLKNRNRAVDPCLNSEIEAAPANHHNPSRPSRIEYFTTPATLLVRSPNPSPSETNPFTKTNLQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6I6</accession>
    <name>A0A8T0J6I6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G105400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035730172" evidence="1">
        <location>
            <begin position="19"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6875" checksum="B4717D071E3D4921" modified="2022-10-12" version="1">MDCLCFLWSLLISHRPHCILIQELQFITIVPVPLNIVHTLIYNDDLHFAAGNSVVCSIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7W5</accession>
    <name>A0A8T0J7W5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G167200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7W5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035847561" evidence="1">
        <location>
            <begin position="29"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="71" mass="8230" checksum="C9E9E499F06A1613" modified="2022-10-12" version="1">MHRMSMIKSDEWLLWMWLASLGVPSTTGAMIRARLDVPNEQIMELFDEDLVTLSLAKWKHAEMMPRGVDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9J2</accession>
    <name>A0A8T0J9J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">glutamate synthase (ferredoxin)</fullName>
            <ecNumber evidence="16">1.4.7.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_1G230200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="15">Amino-acid biosynthesis; L-glutamate biosynthesis via GLT pathway; L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Energy metabolism; nitrogen metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.7.1" evidence="16"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9J2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016040">
        <property type="term" value="F:glutamate synthase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019676">
        <property type="term" value="P:ammonia assimilation cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032366">
        <property type="term" value="P:intracellular sterol transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097036">
        <property type="term" value="P:regulation of plasma membrane sterol distribution"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016125">
        <property type="term" value="P:sterol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050711">
        <property type="entry name" value="ET-N_metabolism_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938">
        <property type="entry name" value="FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11938:SF133">
        <property type="entry name" value="GLUTAMATE SYNTHASE (NADH)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="13" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="17">
        <location>
            <begin position="41"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00037928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00039085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0592165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="187" mass="20848" checksum="AA3A502E6758272B" modified="2022-10-12" version="1">MCACGTPVAAVYVDHAPGNIRLSECAQCGYAADEYVECEMMVAEALGHTVLGWRRIKTDNSDLGYSAIQTEPMIEQVFLTKSSMSTIDFENQMYILRKTSMLAIRAALNLKRGASKDFYICSLSSRTVVYKGQLKPNQLCILFIADPKFLIRQSLSFSLTLSHWHTTDSVVGLDLFVLRMDMLGQAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDG3</accession>
    <name>A0A8T0JDG3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">COBRA C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G301800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the COBRA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDG3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010215">
        <property type="term" value="P:cellulose microfibril organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056900">
        <property type="entry name" value="COB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006918">
        <property type="entry name" value="COBRA_pln"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31052">
        <property type="entry name" value="COBRA-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31052:SF3">
        <property type="entry name" value="COBRA-LIKE PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25079">
        <property type="entry name" value="COB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04833">
        <property type="entry name" value="COBRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035793321" description="COBRA C-terminal domain-containing protein" evidence="8">
        <location>
            <begin position="31"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="684"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="COBRA C-terminal" evidence="9">
        <location>
            <begin position="456"/>
            <end position="677"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF25079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0593053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="707" mass="77177" checksum="B135C4138F2C07AD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDS8</accession>
    <name>A0A8T0JDS8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G314000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDS8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="42"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="15310" checksum="0C190F70C77A5AE7" modified="2022-10-12" version="1" fragment="single">KKKKKKNLLPQQYSTSNIPHSQHHPLTPLSPNPPAPPPPPCLHHITTTPSLSQSTPLPTPHRLKSPRPSATPDQTSNRRNSREKFTPRSLPAKIHSQRSPNLPSQSMIARTRTPRRSPPPRRIPESRPPRSSSLAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JEC5</accession>
    <name>A0A8T0JEC5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G330900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JEC5"/>
    <dbReference type="OrthoDB" id="1935166at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="21"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0593452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14008" checksum="6D414B4FA7D68BC6" modified="2022-10-12" version="1">MEARADSMHEGSILEEGSVQGDEEGSMQGDDDEEGSMPEHEGLMLEEASSMRLGMTMPTSFTSAEAAVGEVDNIEMASILDLMSDGLAYTLNRKADLEQALLENLLGSLRQEQQKLEADAARLADSLSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5A7</accession>
    <name>A0A8T0G5A7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="7">3.4.21.92</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G075700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="7"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5A7"/>
    <dbReference type="OrthoDB" id="2017408at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009368">
        <property type="term" value="C:endopeptidase Clp complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009536">
        <property type="term" value="C:plastid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051117">
        <property type="term" value="F:ATPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.226.10:FF:000014">
        <property type="entry name" value="ATP-dependent Clp protease proteolytic subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.10">
        <property type="entry name" value="2-enoyl-CoA Hydratase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018215">
        <property type="entry name" value="ClpP_Ser_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001368">
        <property type="entry name" value="PRK00277.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF009205">
        <property type="entry name" value="PRK12553.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381:SF12">
        <property type="entry name" value="ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 5, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="ClpP/crotonase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00381">
        <property type="entry name" value="CLP_PROTEASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0720">Serine protease</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0554240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="301" mass="32272" checksum="77E2465124E4CAE3" modified="2022-10-12" version="1">MANAVLVKPVAAVAPCRATSVHHQLQGSSCTFLPPQPARQSSVSRRLVARAAINSTGFWTPEAVVPNYDIWSIRNDLEAPSGFLGESPRAQGGQGPPPMLAERFQSVITQLFQQRIIRCGGAVDDDMANLIVAQLLYLDAADPNRDIVMYVNSPGGSVTAGMAIFDTMRHIRPDVSTVCVGLAASMGAFLLSGGTKGKRYSLPNSRIMIHQPLGGAQGQQTDIEIQANEILHHKANLNGYLAYHTGQPYEKIVQDTDRDFFMSAKEAKEYGLIDAVISNPLKALRPLPAANGSADPSPTPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5G9</accession>
    <name>A0A8T0G5G9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G067200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5G9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035841851" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7258" checksum="8054257DD8398D47" modified="2022-10-12" version="1">MMVVVGSPNVAQQVPIQFLLILILWFLQSSHCLFCAVQELLNETSSLTTSSHDLGDSNFNCFTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7A7</accession>
    <name>A0A8T0G7A7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA gyrase subunit A, chloroplastic/mitochondrial</fullName>
            <ecNumber evidence="5">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_12G084700</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 17">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Plastid</location>
            <location evidence="3">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="5"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7A7"/>
    <dbReference type="OrthoDB" id="276498at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009330">
        <property type="term" value="C:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.268.10:FF:000001">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.120.10.90:FF:000007">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.40:FF:000002">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.199.10:FF:000001">
        <property type="entry name" value="DNA gyrase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="entry name" value="DNA gyrase/topoisomerase IV, subunit A, C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="entry name" value="Topoisomerase II, domain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="entry name" value="Topoisomerase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050220">
        <property type="entry name" value="Type_II_DNA_Topoisomerases"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01063">
        <property type="entry name" value="gyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004043">
        <property type="entry name" value="PRK05560.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004044">
        <property type="entry name" value="PRK05561.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493:SF5">
        <property type="entry name" value="DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43493">
        <property type="entry name" value="DNA GYRASE/TOPOISOMERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="GyrA/ParC C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="Type II DNA topoisomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52040">
        <property type="entry name" value="TOPO_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Topo IIA-type catalytic" evidence="14">
        <location>
            <begin position="206"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="120"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="146"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="162"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="12">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00074255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS52040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0554357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1021" mass="111079" checksum="F3F1E53588D110DD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G918</accession>
    <name>A0A8T0G918_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G179700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G918"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035859848" evidence="1">
        <location>
            <begin position="18"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="201" mass="22721" checksum="53CE6991CC9A39F1" modified="2022-10-12" version="1">MRHLLLNPLTLIMTASGMEHQIVENLVNQAAEHRIQKNSNRNAHSLVPVGSSVVALRLLPPELAELAAHDGAPLHARHHYLEPVEVRHRRPPGAHRQLLPPRAARPLLLHLRVLVRLPQHLLGRRARQLRDGDVRQRQPLEVDLRPHHVGRVHERAVLVDDVHNHHQLAVVGPVVHERHPSNLNEATEHHGGSRAMVVQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9J2</accession>
    <name>A0A8T0G9J2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G019200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9J2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="401" mass="43577" checksum="96F9A44FC479BB19" modified="2022-10-12" version="1">MKTPLSDASSCSGVPLCITDLELGKMGVLATMPGSIFTELPIWASSSRFPIPVCIGTIRGRRFCSSWLRVSDQRYSARTRSGVVVCCNGDGNNHEGSDERGSSWDEGSKPSEVSRLHAENSELRASLAELSKSLASISGALAEVSRAVELVARAVDRGPSENGGFGVSALVASPAPEIAAVPEISRSQEALSPFSGISSSEKAELEGIQDPVQAQLMEQNMKAHNLAYRLQQAFFQARIEGLGKPFQLAAEDFVATCLEAHAMGIGLKELQLQLILLEGSLSDAFAIRNQRHSDDPVMSEESRVRSSWVRLVYTTLAEVKERRSRVEYAASDVGKVREQPDPSDDFVRQLVTLAFEQGYDLERVKLEQNVAGPVTSVAIKTMRQCTYLVLLTLQKITNDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCN5</accession>
    <name>A0A8T0GCN5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G180600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="56"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="387"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="754"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="1099"/>
            <end position="1487"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="781"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="1126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1495" mass="168680" checksum="27BE31F534C3B951" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD14</accession>
    <name>A0A8T0GD14_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF7748 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G118700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056650">
        <property type="entry name" value="DUF7748"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48468:SF1">
        <property type="entry name" value="PLASTOCYANIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24928">
        <property type="entry name" value="DUF7748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7748" evidence="1">
        <location>
            <begin position="6"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF24928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="14835" checksum="22DDAE07FB9D1AA4" modified="2022-10-12" version="1">MAATIQTKVFNGTDKALELKEGNGGNYRYLDTIPKNESSKIDCDVNATYREYWVGTAAGIAEVVITSDDCAECSDIRIVPAGVGRSKLEKTLRSPAATQAVSTSNKWSFFSLFTRKKVELFKGEAEQPTSSPTTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDL3</accession>
    <name>A0A8T0GDL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G120800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005504">
        <property type="term" value="F:fatty acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009627">
        <property type="term" value="P:systemic acquired resistance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.110.10">
        <property type="entry name" value="Plant lipid-transfer and hydrophobic proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036312">
        <property type="entry name" value="Bifun_inhib/LTP/seed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016140">
        <property type="entry name" value="Bifunc_inhib/LTP/seed_store"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039265">
        <property type="entry name" value="DIR1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122:SF75">
        <property type="entry name" value="BIFUNCTIONAL INHIBITOR_PLANT LIPID TRANSFER PROTEIN_SEED STORAGE HELICAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33122">
        <property type="entry name" value="LIPID BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14368">
        <property type="entry name" value="LTP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00499">
        <property type="entry name" value="AAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47699">
        <property type="entry name" value="Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5036274478" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical domain-containing protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Bifunctional inhibitor/plant lipid transfer protein/seed storage helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="12503" checksum="433F62CC9C069468" modified="2022-10-12" version="1">MAMVMRRSSGMLMWGVVAMAVVLGFGSTVVESQAQCGGSDLTKLYACLSAARADVVPSTSCCQALSSFNSDAGTACLCSASTDPRFTSSGGKPELAVLIPQKCNLRYKAGIVCNGILIPGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDR7</accession>
    <name>A0A8T0GDR7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G125800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="475" mass="54204" checksum="C0DAC5D075207E6D" modified="2022-10-12" version="1">MAKDKDKAKNSGEVVSPWTDDSGPDILEIVNDPKNRDQLSPANLGELLTKCPVYQLENAWKIIGSPCKFPPTPDEISKNTWMRQWTPISFKDIYKRSYHRYHPVLMETGTKLFYVVSFDPGTLNKDMGYNWIALPPLNFLPPGCERVIAGSAGLVVMDGGEQPGSGPIMLWGQMQVPNAKFWQNGKFKKQFGGQSLVCVANPLTREFILLPPIPNRRVHDKIAKFVFGDMERSKYYLVIAGWDTIKRKKQNKLVDILCVIVYSSEKQGFVHANYIEKARPIPFHECGRSGMAIINYGVYFGGQRVIERVDDEENCVPAIYYFNISDSRRQCLCFDFNLVNMAGREIQAPKVVQAGPDRVFAITRFAQLPTIIWIVEVELHPDGTPTGSYRKIHCGVMPGHFYELLFPTEDEALLPYECTSADGVIAIKVYSERNLMVSYHIDKREWRLFKFPHHQDQKNFQLCDGCYEPVFTARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEZ8</accession>
    <name>A0A8T0GEZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G143600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050836">
        <property type="entry name" value="SDS22/Internalin_LRR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652">
        <property type="entry name" value="LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46652:SF3">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Myb-like" evidence="4">
        <location>
            <begin position="99"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="219"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0557610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="704" mass="79670" checksum="CDD68CCDEEBB0DA3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGF3</accession>
    <name>A0A8T0GGF3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G004300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGF3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="57843" checksum="ED1AF26E5D25B75D" modified="2022-10-12" version="1">MPKNKKQKNVGEWANKFNDMPSLRCKDYIVALIVEFYQENTLVSLNSRYVRYEEDGPRKFKSEMETKIRDRLMDPCWHSDTQKPGYDHFVSQRAHDALWNAKEVITKYAKAQRRGVHAFKDTIAKADCFTRLMAPHSSRKHRRASITWWNSPIGMETAADLRKRHLTILADFAVFYYLDKEVQRGGYATIRRVRIEGNPQIPPYWEFAEKRPLNWSMRPDLARVDHNNESLAIRIPHPRVIRFQAIHQLEHVRFMFWWNGGTLRAMLQRDNEAPGDLPIDYIFRENADDSPILGKRLQLFRSKRTELAWALCNIIDAVHKYGYLHNDLSPDNILLHFPEDESKIYIGVCDWGLMTKTLENRRSPWVFENVHQKEETMRRRYWVDPRVVYVDKENQDIQIIPDLTVASEDFAAAKIAAKINRGNMCTAYHKAEPVETRHFQNIGELAMVFEGYLERVCQNNRGTIGGLGHLINRFRDTHNWPTPVEHYREGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHX5</accession>
    <name>A0A8T0GHX5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G076900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHX5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36003">
        <property type="entry name" value="TONB-DEPENDENT HEME RECEPTOR A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36003:SF5">
        <property type="entry name" value="TONB-DEPENDENT HEME RECEPTOR A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="147" mass="16352" checksum="8E26AAE3AC941D6A" modified="2022-10-12" version="1">MAYITAHLEPITYFHTHLKHELRLRLSETRPEFHRLHKLDKIAGLRPDFSPPQQSFLVMASSAAATAVRRAVAKIAPPASSGVRQFHATGAKRYSDDYIHADHMYNITAMKNRKLKMGVGVFGSLAIGIMVPIWAVQFQMKKAGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI73</accession>
    <name>A0A8T0GI73_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G170800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI73"/>
    <dbReference type="OrthoDB" id="29013at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043376">
        <property type="entry name" value="NPG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44102">
        <property type="entry name" value="PROTEIN NPG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44102:SF5">
        <property type="entry name" value="PROTEIN NPG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13176">
        <property type="entry name" value="TPR_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="574"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="608"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="679"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="726" mass="80575" checksum="571D4669185143F4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIT7</accession>
    <name>A0A8T0GIT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G103800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11069" checksum="FB3C88480C11DB6C" modified="2022-10-12" version="1">MYVGVRRHELALCWIDQVLLLWKPGGYELKSDVLFRVDRCVSGGVWNSGSAWFCDNSCSSLQVMICCKLVFGVPCLVQEWNYLGFAVSCVDVRGLICGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJY9</accession>
    <name>A0A8T0GJY9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G127900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJY9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007877">
        <property type="entry name" value="DUF707"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210">
        <property type="entry name" value="OS06G0731900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31210:SF47">
        <property type="entry name" value="OS07G0564800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05212">
        <property type="entry name" value="DUF707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="49026" checksum="60A0A9E27B571AC4" modified="2022-10-12" version="1">MLGFRTWLKQSPVICPYTDSASGKNPTINSCWTKFLRQSRLFYGAALMIGFMLVLSTMFVNEHNFKDAFVNKLSGSLKDSVKEPCFLTKTHCSRGGAEALPRGIIVETSDLQFRSLSYEEESEVAESMPKNLLAMAVGIKQKKDVDEIVQKFPLTNYTIMLFHYDGVVDQWQDLPWSNQSIHIVGLHQTKWWFAKRFMHPDIIAQYNYVFLWDEDLGVEHFHADKYLEVMEAEGLEISQPALDPASADIHHALTRRQSSGRAHKMILRNRGSTICTRESNGPPCTGYVEVMAPVFSRAAWRCVWYMIQNDLVHGWGIDFKIGYCAQGVRSEKVGIIDAEYILHKGIPSLGGPRLNKTLEQEDVEKTFVKGKKHSPGKQSDLRREVRKRSGSEMLAFLRRWKTAAKRDHTWKDPYKVLNDSSGNYHRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKG0</accession>
    <name>A0A8T0GKG0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G048900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKG0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="22"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="20185" checksum="2E9C09D68B0E6CE8" modified="2022-10-12" version="1">MDTVSSSHITPKPLHHCHQQRPSPPPPPNQQPPPPSPPHSLLFHPTLHPIEPSPFPNAASSQPRRGTPARAPTDIPEAPATLKPHCRSLPCSQQPSFCPMRSCHSWFHEHVPTPNQHSSPPSIFSVYELCAFPATSKCKPYASASTLNLYAIRDDDGFHPKFNAYVARRLFWAESGLKEALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM32</accession>
    <name>A0A8T0GM32_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="19">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">KC19_10G193600</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="20" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="20">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM32"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000168">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase IX.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000108">
        <property type="entry name" value="L-type lectin-domain containing receptor kinase S.4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 18" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035899598" description="Protein kinase domain-containing protein" evidence="18">
        <location>
            <begin position="29"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="19">
        <location>
            <begin position="373"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0560616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="718" mass="79622" checksum="84E433E51AEF6D9B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMH7</accession>
    <name>A0A8T0GMH7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G103500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035917425" evidence="1">
        <location>
            <begin position="23"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="13026" checksum="594D6108CB67DD28" modified="2022-10-12" version="1">MQGHGSSSLLLVSLEGVYTCVAIGYSKLSVEGRTGDNCNLFSTRGSKTSPLFMRCVLGSVVAGREYYRVVFDRFNRTYMSTYYVCFVSFDTVAKSQNRTSKVIVQYGLPVGSSLSKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQK6</accession>
    <name>A0A8T0GQK6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">40S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G191100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQK6"/>
    <dbReference type="OrthoDB" id="1901524at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.2650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_eS6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014401">
        <property type="entry name" value="Ribosomal_eS6-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_eS6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="40S RIBOSOMAL PROTEIN S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002129">
        <property type="entry name" value="Ribosom_S6_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="224"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR002129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0560579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="247" mass="28172" checksum="8F1BF4788CF7E234" modified="2022-10-12" version="1">MKLNIANPTTGCQKKVEIDDDAKLRQFYDKRLAQEVSGDQLGDEFKGYVFKIMGGCDKQGFPMKQGVLTQGRVQLLMHRGVSCFRGHGRRNGERRRKSVRGCIVSPDLSVLNLVIVKQGDNDLPGLTDIEKPRMRGPKRATKIRKLFNLTKEDDVRKYVNTYRRSFVSATGKKRSKAPKIQRLVTPLTLQRKRQRVAVKKQRVAKAKTEAAEYQKLLALRIKEQREHRSESLAKKRASRASIAKPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRI7</accession>
    <name>A0A8T0GRI7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G024600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0560919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11300" checksum="BC576AC869A96F23" modified="2022-10-12" version="1">MGSTNSLDPSTTRTTTIIAKPRHLTTRTVALTSQVTCLQSLQSYKSSLSVYNTNFTAPETPQLFDQTALTQTDRLSASALASDYYFEHSDSSLYNHPASTSSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRL6</accession>
    <name>A0A8T0GRL6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_9G134800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRL6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12094">
        <property type="entry name" value="TM_ErbB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000095">
        <property type="entry name" value="protein STRUBBELIG-RECEPTOR FAMILY 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000466">
        <property type="entry name" value="Putative LRR receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974:SF119">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45974">
        <property type="entry name" value="RECEPTOR-LIKE PROTEIN 55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035718454" description="Protein kinase domain-containing protein" evidence="15">
        <location>
            <begin position="28"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="231"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="16">
        <location>
            <begin position="317"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0562296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="643" mass="69943" checksum="26ABA68CF9035321" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRQ7</accession>
    <name>A0A8T0GRQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Photosynthesis system II assembly factor Ycf48/Hcf136-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G175600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028203">
        <property type="entry name" value="PSII_CF48-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010237">
        <property type="entry name" value="PRK13684.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY/ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47199:SF2">
        <property type="entry name" value="PHOTOSYSTEM II STABILITY_ASSEMBLY FACTOR HCF136, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14870">
        <property type="entry name" value="PSII_BNR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110296">
        <property type="entry name" value="Oligoxyloglucan reducing end-specific cellobiohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="2" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photosynthesis system II assembly factor Ycf48/Hcf136-like" evidence="3">
        <location>
            <begin position="107"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="429" mass="45553" checksum="90251769BA1C1B47" modified="2022-10-12" version="1">MAALGTQALSLLSSGVLKAPGSSSTSRCSAIGSFCGLRGDVGKVVAAPVRQCASKGSCVVVASREEEEEEEELVGGVSRRRVLAGAAGGALALGGALGDQGVALADETVSSWEQVTLPVDAGVVLLDMAFVPDQPDRGFLLGTRQTLLETKDAGRSWNSRSIPSAEDEDFNYRFNSISFQGKEGWIIGKPAILLHTSDGGENWERIPLSIRLPGNPVIIRATGPQSAEMVTDEGAIYVTSNNGYNWKAAVEETVSATLNRTVSSGISGASYYTGTLNTVNRSPAGDYVAVVSRGNFFLTWEPGQPYWQPHNRTSARRIQNMGWRADGGLWLAVRGGGLLVSRGTGVTEDFDEQKIPSRGFGILDVGYRSKDEAWAAGGSGILLRTTDGGKSWVRDRVADQIAANLYAVKFIDNKGFVLGNDGVLLRYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRW8</accession>
    <name>A0A8T0GRW8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="6">2.2.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G034700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="6"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019682">
        <property type="term" value="P:glyceraldehyde-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07033">
        <property type="entry name" value="TPP_PYR_DXS_TK_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000005">
        <property type="entry name" value="1-deoxy-D-xylulose-5-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049557">
        <property type="entry name" value="Transketolase_CS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003933">
        <property type="entry name" value="PRK05444.2-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="1-D-DEOXYXYLULOSE 5-PHOSPHATE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322:SF5">
        <property type="entry name" value="1-DEOXY-D-XYLULOSE-5-PHOSPHATE SYNTHASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="TK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transketolase-like pyrimidine-binding" evidence="13">
        <location>
            <begin position="402"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0561069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="743" mass="79507" checksum="3B076C737D9B6417" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSV6</accession>
    <name>A0A8T0GSV6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ZF-HD dimerization-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_9G009900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSV6"/>
    <dbReference type="OrthoDB" id="694008at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050793">
        <property type="term" value="P:regulation of developmental process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000257">
        <property type="entry name" value="Zinc-finger homeodomain protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006455">
        <property type="entry name" value="Homeodomain_ZF_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006456">
        <property type="entry name" value="ZF_HD_homeobox_Cys/His_dimer"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01565">
        <property type="entry name" value="homeo_ZF_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01566">
        <property type="entry name" value="ZF_HD_prot_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31948">
        <property type="entry name" value="ZINC-FINGER HOMEODOMAIN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31948:SF140">
        <property type="entry name" value="ZINC-FINGER HOMEODOMAIN PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04770">
        <property type="entry name" value="ZF-HD_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51523">
        <property type="entry name" value="ZF_HD_DIMER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZF-HD dimerization-type" evidence="11">
        <location>
            <begin position="61"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0560748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="254" mass="27674" checksum="C1C8C10076A9709C" modified="2022-10-12" version="1">MESLVSHKIDYTPMPITANFAGFHEFSKLKLLSSVNGVTNMDEHRPLDAANVKAKAKAVRYRECNRNHAINSGGHAVDGCGEFMPSGEEGTVEALKCAACNCHRNFHRKEVEGEPTCDCKNIRNIQDARKQGLMARGAPSQPGGSQPLALPSPAQIISRVTQSAPYLLGPGPADSDDGDGGLSGSPSNIKKRFRTKFTTEQKEKMGAFAEKLGWKIQKHDEAAVQEFCADVGVKRHVLKVWMHNNKHTIGKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTC0</accession>
    <name>A0A8T0GTC0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_9G122800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
            <location evidence="2">Cytosol</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="5">
        <location>
            <begin position="574"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="231"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1451"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="8"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1463"/>
            <end position="1476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0562163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1495" mass="165806" checksum="327CD3C7F17EA6C3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTZ1</accession>
    <name>A0A8T0GTZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G150000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTZ1"/>
    <dbReference type="OrthoDB" id="1873431at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="23533" checksum="B97A26CADFB23885" modified="2022-10-12" version="1">MSSKCQLKVVPRKPIPNWIDSITKKWKYVDPGHRYCVPGFKAASFTPKNKAEKYNGRTHNCYAAVTTNNGDRYSFMHPHRKTGFKAGNAYGKTPLFDGLTTKNYFDHLVRKVGEEMDLMSKKLCPYNVGAGRNMPRDKSHNDVGLHCFDRRNASYITLESGDRRDMKTPLSTHQRFHVLPRSKTGLSNPGIFAEKTVLMHKHQMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GVZ8</accession>
    <name>A0A8T0GVZ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G012200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GVZ8"/>
    <dbReference type="OrthoDB" id="10596944at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="23386" checksum="776C83260CF035E6" modified="2022-10-12" version="1">MWNRRFKTLITDSKERGKILIKLLALPESERDLIFDDGDDAVVTSLLSLIEEDTSPPRLVYRMQNNVGFARMTLQTPYTAPFEDDFMIDTGCGMELLLPKSYHEQVQVTAVLVKKGSGEFAMKKVKYLTPFVLTDAQVPEGGIFEEAPMPHVSDDIQPMDINAILRLSSTSTSDVGGGCILGLPGLLSLGLEVHVSKQYLYPTSIVRALAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYC4</accession>
    <name>A0A8T0GYC4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thaumatin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_8G078300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thaumatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYC4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd09218">
        <property type="entry name" value="TLP-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.110.10:FF:000002">
        <property type="entry name" value="Thaumatin-like protein 1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.110.10">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037176">
        <property type="entry name" value="Osmotin/thaumatin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001938">
        <property type="entry name" value="Thaumatin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017949">
        <property type="entry name" value="Thaumatin_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31048">
        <property type="entry name" value="OS03G0233200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00314">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002703">
        <property type="entry name" value="Thaumatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00347">
        <property type="entry name" value="THAUMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00205">
        <property type="entry name" value="THN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49870">
        <property type="entry name" value="Osmotin, thaumatin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00316">
        <property type="entry name" value="THAUMATIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51367">
        <property type="entry name" value="THAUMATIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035730163" description="Thaumatin-like protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="36"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="99"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="153"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="158"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="166"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="185"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="195"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR002703-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0564040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="250" mass="25408" checksum="9645EB1B5FAD42D4" modified="2022-10-12" version="1">MAMAARLLLSVLVVLQLASCMLQGADAVTFTFINSCKFTVWVGLQPNGGLPLLADGGFQVLQGAQHAVTAPVGWGGRFWGRTGCVFDARGKGTCETGDCGGVLKCNGAGGTPPASLAEITLNGANNDDFYDVSLVDGYNLPIAMTPLGGTGNCGAPGCVSNLNHNCPSALQLMAAGAVVGCKSACVTFGAPQYCCTGAYGAPTTCPPTQYSLPFKAACPTAYSYAYDDATSTFTCQAPSYAITFCPAGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZA2</accession>
    <name>A0A8T0GZA2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G066500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZA2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043682">
        <property type="term" value="F:P-type divalent copper transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055070">
        <property type="term" value="P:copper ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02094">
        <property type="entry name" value="P-type_ATPase_Cu-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000002">
        <property type="entry name" value="Copper-transporting ATPase 1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.100:FF:000047">
        <property type="entry name" value="Copper-transporting ATPase PAA1, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01511">
        <property type="entry name" value="ATPase-IB1_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520">
        <property type="entry name" value="ATP7, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43520:SF22">
        <property type="entry name" value="COPPER-TRANSPORTING ATPASE PAA1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00943">
        <property type="entry name" value="CUATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="HMA, heavy metal-associated domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="319"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="411"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="618"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="931"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="956"/>
            <end position="980"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="207"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="991"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="999"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1012"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0563877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1041" mass="108166" checksum="5267C3CA5B5AA992" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZZ1</accession>
    <name>A0A8T0GZZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G149400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="9651" checksum="CE13E64E6458094A" modified="2022-10-12" version="1">MHRFGFDRPQHLLQECRSLSPQIGLNSSEHRHRFADGCICYSPYHHFTFLCCTWTYTSELIHHHKKRFGFTIFHFDGHSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0M1</accession>
    <name>A0A8T0H0M1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase</fullName>
            <ecNumber evidence="1">3.2.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_9G165100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>NAD(+) + H2O = ADP-D-ribose + nicotinamide + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16301"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57967"/>
            <dbReference type="EC" id="3.2.2.6"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:16302"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.6" evidence="1"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0M1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061809">
        <property type="term" value="F:NAD+ nucleosidase activity, cyclic ADP-ribose generating"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32009:SF39">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32009">
        <property type="entry name" value="TMV RESISTANCE PROTEIN N-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="7">
        <location>
            <begin position="81"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0562692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="333" mass="37933" checksum="9EAD59F58207171E" modified="2022-10-12" version="1">MSNCIEIEVVLLKAPSVSKSVDTEPVSDEEREQEPLLHSRKLEDVSKSVDIEAEYSEELDQEPWLHVEESETDWDTVQLKSKHTMFLSHSGAQKGFVEQLCEDLERAKQVPFFDKRPDSLPKGEKFAQLIFQAARQCPLAIVVVSEEYFTRSKWPMLELGAFVQTGNCTILPLFLGITCKEFGDVKRREGWFRRWSEWAQEDPRIHVDVWKEALRDLDGRNGLEFSEALGEVAYRKEVVATACTILAKNVQLRDQRLPEMVSDLLDMLRGVALLSCSMIVMVLVGFGILAPLFFKFVDYAVIPQIEGFGDMTQPSRSLPKPRCTVNGRPFVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1P1</accession>
    <name>A0A8T0H1P1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_8G097700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1P1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005891">
        <property type="term" value="C:voltage-gated calcium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005245">
        <property type="term" value="F:voltage-gated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18773">
        <property type="entry name" value="PDC1_HK_sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="entry name" value="von Willebrand factor, type A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051173">
        <property type="entry name" value="Ca_channel_alpha-2/delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166:SF37">
        <property type="entry name" value="STOLID, ISOFORM H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10166">
        <property type="entry name" value="VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="vWA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035847248" description="VWFA domain-containing protein" evidence="3">
        <location>
            <begin position="40"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="550"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0564274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="610" mass="65125" checksum="BDA42B3F71AF191C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H4Y3</accession>
    <name>A0A8T0H4Y3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAM192A/Fyv6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G054200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H4Y3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039845">
        <property type="entry name" value="FAM192A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019331">
        <property type="entry name" value="FAM192A/Fyv6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495">
        <property type="entry name" value="NEFA-INTERACTING NUCLEAR PROTEIN NIP30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13495:SF0">
        <property type="entry name" value="PSME3-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10187">
        <property type="entry name" value="FAM192A_Fyv6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAM192A/Fyv6 N-terminal" evidence="4">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="115"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0566310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="191" mass="21638" checksum="B031F053197EA4C5" modified="2022-10-12" version="1">MAEPKLKLMNFVTASQTDAEIESVPSETQQKQEVYDDRPLHQILKENAEKKDAEFNERFKHRPPKALDEDETEFLDALETYRKQQEQDVADDEARELTNFHTAIANRTITTEEVRPSTIGAVQSEKPSLTNKRPQPKLPLAVSVKIKSQPKKARTESPPAIPQDLNVSADKKVEESNCFGLVAYSDESDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H579</accession>
    <name>A0A8T0H579_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G180300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H579"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="155" mass="17555" checksum="53BE0A099AB6B377" modified="2022-10-12" version="1">MEQSISLLQVVDKRIAVYETLKLSIHMVAFSGYLLCATFVFFTLSTRWLAHIPGYWSINCIDSTDVVAGILVLVHSFKPTICGSRNHLLEGVHWYTNVQSICLDSIVNEVRTIYITAIFFSGVKLGPANLRILCSIPVYEQALIHLQRFTCYCLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5E6</accession>
    <name>A0A8T0H5E6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_7G069900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5E6"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF117">
        <property type="entry name" value="XYLOGLUCAN-SPECIFIC GALACTURONOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <feature type="domain" description="Exostosin GT47" evidence="5">
        <location>
            <begin position="236"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0566523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="639" mass="72333" checksum="696AD511F4A2C74A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8D7</accession>
    <name>A0A8T0H8D7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Tyrosinase copper-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G067700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tyrosinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8D7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004097">
        <property type="term" value="F:catechol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1280.10">
        <property type="entry name" value="Di-copper center containing domain from catechol oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008922">
        <property type="entry name" value="Di-copper_centre_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022740">
        <property type="entry name" value="Polyphenol_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022739">
        <property type="entry name" value="Polyphenol_oxidase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050316">
        <property type="entry name" value="Tyrosinase/Hemocyanin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474:SF76">
        <property type="entry name" value="SHKT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11474">
        <property type="entry name" value="TYROSINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12142">
        <property type="entry name" value="PPO1_DWL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12143">
        <property type="entry name" value="PPO1_KFDV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00264">
        <property type="entry name" value="Tyrosinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00092">
        <property type="entry name" value="TYROSINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48056">
        <property type="entry name" value="Di-copper centre-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00497">
        <property type="entry name" value="TYROSINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0186">Copper</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0883">Thioether bond</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035895111" description="Tyrosinase copper-binding domain-containing protein" evidence="8">
        <location>
            <begin position="30"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="9">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosinase copper-binding" evidence="10">
        <location>
            <begin position="303"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0566488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="543" mass="61669" checksum="3A86A7C47844C0CB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8Y5</accession>
    <name>A0A8T0H8Y5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G015100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8Y5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="256" mass="29140" checksum="C680F1419A5EF140" modified="2022-10-12" version="1">MARVEGGACGVSRILGTTMPTRDNWLDTEWVSALHGLSSRGVTLAAFQLWCRNVSLGNPIAPDMDTHTRKRGLVEVLPNLFLNKEALLSKLPALRLFVSGLEEHRFHEEAYLQEIKAYLELHKLMYWGRPDVTIVVRCRLSPSEKGVPVRVQQFYSRVLPIDKRASCVTVQEGSKGTSDYIRPWIMQCGSSIGIHRTKKVARMIAIIKHHLDPSFDPEDDSPPPTMCGLWNEIFQSRKRKLEQVIDKPESELDPYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2024-11-27" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H989</accession>
    <name>A0A8T0H989_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G002800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032039">
        <property type="term" value="C:integrator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034472">
        <property type="term" value="P:snRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029321">
        <property type="entry name" value="INTS2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28608:SF1">
        <property type="entry name" value="INTEGRATOR COMPLEX SUBUNIT 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14750">
        <property type="entry name" value="INTS2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1298" mass="140661" checksum="3F6C19C8D9E46E57" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9Q2</accession>
    <name>A0A8T0H9Q2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fe-S metabolism associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G108400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9Q2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597:SF5">
        <property type="entry name" value="SUFE-LIKE PROTEIN 2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="SULFUR ACCEPTOR PROTEIN CSDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S metabolism associated" evidence="3">
        <location>
            <begin position="106"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0567074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="233" mass="25166" checksum="E900D914E5CB1B25" modified="2022-10-12" version="1">MAMAVLSSSSSSVSLARLPSSPSAASKPHHQPRVTLPGLPLHQIAICKLSPSKPSHASSPQRAPSRALNQALNTTRNWALASTAQVHPTETAGDELPANLQKIVHLFQAVGEQRARYQQLLYYGQKMMPLAKEHCIPENKVNGCVSQVWVVCKLRDDGRVYFQAESDSALTKGLAALLVEGLSGATPGEVLKVSPDFMQKLGLQQSLTPSRSNGFLNMLKLMQKKTTQAYSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9Y5</accession>
    <name>A0A8T0H9Y5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G102000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9Y5"/>
    <dbReference type="OrthoDB" id="4882at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.70:FF:000003">
        <property type="entry name" value="tRNA (Adenine(37)-N6)-methyltransferase isoform A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00104">
        <property type="entry name" value="tRNA_TsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818:SF0">
        <property type="entry name" value="TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="YaeB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="92"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="436" mass="47961" checksum="2152AC0AACA3CED8" modified="2022-10-12" version="1">MHITAMGNPASQWTVLLSLAAAAAATIAVSAFSLQEWRKRLLARIAELENQLASAHKQRQAERMGRIRGQRELRQALLSSKDEKAGSASYPMTPIGLIRSCFSTRNGTPRQPMLVTLARGSLVLSSKNVAAEAFDGLSQYSHCWLIYVFHENTDLPGLWKQPPHKDFKAKVRVPRLDGGKMGVFATRTPHRPCPIGLTVAKVEGIQGATLLLSGADLVDGTPVLDIKPYLPYCDSVPAAVAPSWVKAGGDDDVIAMASVDFTEAFSEELAKCWETMGKLSLYSSWMEFQGLLKQVLSRDIRSLSQRQKPHNAILSALNEQYLNAPKDVSFDPLQKALDNAENFDQADLVVDADQSTPVVDKTEDAEASTLDAEYEKIERDDKVVYHLVLEGVDVSYTLLEDGKVVVEGASLTKALKPPASRDFDPRNWRHLFTNTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEM6</accession>
    <name>A0A8T0HEM6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="5">4.2.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_6G112800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="5"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEM6"/>
    <dbReference type="OrthoDB" id="10253554at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05260">
        <property type="entry name" value="GDP_MD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000102">
        <property type="entry name" value="GDP-mannose 4,6-dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.25.10">
        <property type="entry name" value="UDP-galactose 4-epimerase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715:SF1">
        <property type="entry name" value="GDP-MANNOSE 4,6 DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="GDP-MANNOSE 4,6-DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-binding" evidence="9">
        <location>
            <begin position="13"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00059383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0569740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="353" mass="40042" checksum="39060D3C2AE93BC3" modified="2022-10-12" version="1">MAPEVAAPMRKALITGITGQDGSYLTEFLLKKGYEVHGIIRRSSNFNTQRLEHLYIDPHQSSARMKLHYGDLSDASALRKWVDSICPDEVYNLGAQSHVGVSFENPDYTADVVGTGALRLLEAVRIHIESTGRQVKYYQAGSSEMYGATPPPQDETTVFHPRSPYAVAKVAAHFYTVNYREAYGIFACNGILFNHESPRRGENFVTRKITRAIGRIKVGLQKKLYLGNLKASRDWGFAGDYVEGMWLMLQQEKPDDYVLATEDSHTVEEFLEESFTYVGLNWKDHVEIDPRYFRPSEVDNLRGSAKKAKEILKWEPKVQFKQLVAMMVDADLEKAQREKVLVDAGFIDSHQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEP4</accession>
    <name>A0A8T0HEP4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G066700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEP4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035891790" description="Secreted protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="74" mass="8267" checksum="2CCA2944B481A511" modified="2022-10-12" version="1">MVVLVTCICTALNNLLCFAMSRLSENYQFCDFSFYGAIDCFTARSCQDWRGPLSWLLSAFTSATESGKWSGDDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HET4</accession>
    <name>A0A8T0HET4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G042500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HET4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039218">
        <property type="entry name" value="REM_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN REM-LIKE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31674:SF25">
        <property type="entry name" value="B3 DOMAIN-CONTAINING TRANSCRIPTION FACTOR VRN1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="5">
        <location>
            <begin position="19"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0568744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="260" mass="28563" checksum="31034DBE28929C56" modified="2022-10-12" version="1">MLTELEELVLEDLDEAEVTYFSVRIISKTNPARLEVPASFTATTGWPGAVQCSLLTSLRDPKEWPLQMGQLPSSSCVGNAVSDSTGWANFLRHMAVSVGDIIVFEFVDSRCLVASIAYHRGCPPQNVPEEPQVVNVIVPAEPQVVSVNVPELPQVVNVNSPFFKKKLRATHARAHKSARLDIPTAFWRAVGPEKFNGSLITLSGPGGEHVVQSSICVTPKQTFCFFGSGWSDFRALNDFHVGDTIVFTKVTECQYEVIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIQ7</accession>
    <name>A0A8T0HIQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_6G108400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HIQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035789157" description="Secreted protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0569692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="7925" checksum="C964CB623D805991" modified="2022-10-12" version="1" fragment="single">MVTSATCTMPTVSLLVISSFLQICLANIHSNLGVKFSVHSPNYAFFISLFAKLATFSLQLLHSRRIPQLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMP7</accession>
    <name>A0A8T0HMP7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG068000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMP7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="182" mass="19250" checksum="A4CA8F3627195ED9" modified="2022-10-12" version="1">MATKNSKQALRDRLQVKNGGCLFERSVPWQGFVPRLLSSSRQCGAKGDVSDSQLNLEGVLKWGRASGVEGERVILLSWELESLLTCHFGEGNVIIVREGEFAAGRGGLLLGGGNIRGVGQLVSLVPDLLLEARGVRGSRFGRGVRYLFVELRCGVGAECGGFGNGGASFGASRADYAGRHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN05</accession>
    <name>A0A8T0HN05_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exostosin GT47 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG076200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN05"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="50" mass="5912" checksum="62E3DBEF584F3B7B" modified="2022-10-12" version="1">MLKMMADIVMAYVESLIIKYPYWNRTLGADHFFVTCHDIGILTFYHQLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN59</accession>
    <name>A0A8T0HN59_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10">Beta-amylase</fullName>
            <ecNumber evidence="3 10">3.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_VG085600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Hydrolysis of (1-&gt;4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.</text>
            <dbReference type="EC" id="3.2.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the glycosyl hydrolase 14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.2" evidence="3 10"/>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN59"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016161">
        <property type="term" value="F:beta-amylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001554">
        <property type="entry name" value="Glyco_hydro_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018238">
        <property type="entry name" value="Glyco_hydro_14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31352:SF31">
        <property type="entry name" value="BETA-AMYLASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01373">
        <property type="entry name" value="Glyco_hydro_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00750">
        <property type="entry name" value="BETAAMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00506">
        <property type="entry name" value="BETA_AMYLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00679">
        <property type="entry name" value="BETA_AMYLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 10" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="433"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="514"/>
            <end position="515"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601554-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0572330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="612" mass="68571" checksum="15BF68EEB07AF315" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQD9</accession>
    <name>A0A8T0HQD9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG145700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQD9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11318" checksum="F72A686A48D803E9" modified="2022-10-12" version="1">MRLGFGRHGSWCSRNWWCCGGGEMTSFVKGASVCMFLSFLVSASEKEEESVVLGRDFFSWFAVCSCWSELALGAWHSFQFSLVPSHFIPCAWSRPYWGPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQH2</accession>
    <name>A0A8T0HQH2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_VG139000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQH2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0572985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="223" mass="23670" checksum="89EE54344E67CD46" modified="2022-10-12" version="1">MVGLRAFLDNTEGTTVVENVNMLLAYLSFGIGPFIGALKHMLLLSSIDLRVTMATGIGEGVSFVVAAWKPLQMLLDGKMNIFKIFFLLCAGAFLHFLLRKYVEAKSKTSSKIEIVLPGASGELSPKARRACLASFVIWFYTFVEGLAMGVAATSGFYFYLLFPMALHGLPRGVGVGSIVYGATGSRKGSCLAVALTCLASPIGSISAVLTGVGPNQCWSGIII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSE1</accession>
    <name>A0A8T0HSE1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG207000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7992" checksum="1E018BE18D0E0F14" modified="2022-10-12" version="1">MHFGRHQSRRRGRIISVKRTVLLLLQQVWNLIKYFLEYLDVLISVARKTDSVRTGKLTTEKRLKARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUQ6</accession>
    <name>A0A8T0HUQ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG288600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUQ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16410" checksum="23D806B6711A550B" modified="2022-10-12" version="1">MKTSVAVKSRRGTVSGEMKRMEIEDVQEEWIQAERAKTLRRALDDVNRSGQPGPSQVQQEQDSDYEDFFSPSDRVARNPPLDSQIQRGSGGVSMENWTVPELGEDPTPLSTLRFRHIPLILTEGESNKEGSVRRPREENSPERST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVG8</accession>
    <name>A0A8T0HVG8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG291200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="10905" checksum="8CCBF725CC8CF0AA" modified="2022-10-12" version="1">MLPLPAEGAPLVLARRCLVLASSSRTGPPALVRLLSRHDLLTLRNRVGEGKWTYQAGAHPVPPCRPSAALWTTTLQALRSALDRPPCPPLGCRGDLICVYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWK1</accession>
    <name>A0A8T0HWK1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG329100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="175" mass="20047" checksum="76BE05FBD7670743" modified="2022-10-12" version="1">MDRVHKGYLQHNDISPGNVFLHFPEDKVSEVYIGVCDWGLASRVCETTPSRYGYPTTEARTAAFKERGTFVAPELWYTYGKPNSETSYETLRRRHLYTQAADAYSVGVVANKIWDNEDDFDLFKDTSGKTRFAVALKELTNPDPKNRSTLQLVHATLTAPPYNFQIPECCYRKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HY86</accession>
    <name>A0A8T0HY86_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TraB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G033800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HY86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PHEROMONE SHUTDOWN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530:SF7">
        <property type="entry name" value="TRAB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="748"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="127"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="212"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="276"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="771" mass="83353" checksum="D39796FD39737866" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1M7</accession>
    <name>A0A8T0I1M7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Large ribosomal subunit protein uL15/eL18 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_5G126600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1M7"/>
    <dbReference type="OrthoDB" id="61900at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.100.10.10:FF:000002">
        <property type="entry name" value="60S ribosomal protein L27a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_uL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_uL15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_uL15/eL18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="Ribosomal_uL15/eL18_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_uL15_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11721:SF3">
        <property type="entry name" value="LARGE RIBOSOMAL SUBUNIT PROTEIN UL15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="Ribosomal proteins L15p and L18e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein uL15/eL18" evidence="6">
        <location>
            <begin position="72"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0577036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="16316" checksum="E16BCE79083E218B" modified="2022-10-12" version="1">MTTRLKKNRKKRGHVSAGHGRVGKHRKHPGGRGNAGGMHHHRILFDKYHPGYFGKVGMRYFHKTMNKFHCPIVNIDKLWSLVPEAVKEKVDGDKSAPLLDVTQHGFFKVLGKGDLPTQPMVVKAKFFSKLAEKKIKEAGGAVILTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I317</accession>
    <name>A0A8T0I317_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G185800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I317"/>
    <dbReference type="OrthoDB" id="549243at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="CDD" id="cd22163">
        <property type="entry name" value="F-box_AtSKIP5-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045140">
        <property type="entry name" value="SHCBP1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14695:SF4">
        <property type="entry name" value="PROTEIN NESSUN DORMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14695">
        <property type="entry name" value="SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="17"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0577842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="27519" checksum="6F8CE285CD454A3E" modified="2022-10-12" version="1">MPKRACTGLRGSPMQLLDDACLVRILTFLTPLPDRFNAARVCKRWQKLACDKRMWLRVEPDLKPAPNQFTTLQEAVIKARPGDTVLIAPGVTHVTPNILINKPLCLVGGGDSADDTLLLCPRGFDSALEFLANGRLANLKITAELGSCLLHRKGRLTVDSCALECVDHPLDHLSYPIMSTADDQPCPITNGQNEVSVIETRIEGGLRCVNTGDKLKLQQVRVLCGRAAYTFWFQVAKHVSEESPLVYCKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4D8</accession>
    <name>A0A8T0I4D8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G022200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4D8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052867">
        <property type="entry name" value="ATP_Synthase_Subunit_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34565">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34565:SF1">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0578430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="12056" checksum="5B6F8A78432D9CE5" modified="2022-10-12" version="1">MVAPVVGRPLSQVLVSEAKRNWPFVVGFAVTFTLVAKLSASLDPKEAHKSKFVDPYGHHWLCLFSWFFKGFILSCCGWRGRAELFGDVRVNHVLLAVILALQSEPGLSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5Q7</accession>
    <name>A0A8T0I5Q7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">CpSecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_5G178700</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Membrane</location>
            <topology evidence="1 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast thylakoid membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 16">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5Q7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3370.10:FF:000003">
        <property type="entry name" value="Preprotein translocase subunit SECY, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="entry name" value="SecY subunit domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="SECY/SEC61-ALPHA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00303">
        <property type="entry name" value="SECYTRNLCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="Preprotein translocase SecY subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="8 15" id="KW-0653">Protein transport</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="11 15" id="KW-0811">Translocation</keyword>
    <keyword evidence="7 15 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 17" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 15" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="18">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816966" description="CpSecY" evidence="18">
        <location>
            <begin position="24"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="462"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00031059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0577753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="539" mass="57327" checksum="B0D50551B79E205B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6V2</accession>
    <name>A0A8T0I6V2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G049200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6V2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035887564" description="Secreted protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="72" mass="8035" checksum="68B7655B02D79761" modified="2022-10-12" version="1">MRFAGRACSLICFFGVMVWFLVMVPCAGCSFQERLLSECCLKAKGKLLHLGSRAQHACENICLVLYDNRCTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I989</accession>
    <name>A0A8T0I989_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G089600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I989"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="257" mass="27905" checksum="53CDA44E50131E1C" modified="2022-10-12" version="1">MTSTSSGQSNIPTQSTSSGQMPVNSNYPQRPPYLHPWASQMMYSGAVPPSIDSSSQLQYLYQGCQHPSLQNNSVPVPHVRNSMSQFAPTGAMENYRRLSLSHSRAIQQNSSQSHSLSSPISSQLPRSRGGDGSASKDTASGSKGQGSGHTARTEGSDSRMHNSNHSDLPPIPQAPYLPGSTVPWPGWRGASVLSPFDFPPPDMTSPNVSQQQVVFEALPIVPHNPVDVTREEDQGIRYEESKRTAQRRAQRARKASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9X3</accession>
    <name>A0A8T0I9X3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ubiquitin-like protease family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G087800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9X3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.418.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.130">
        <property type="entry name" value="Ubiquitin-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003653">
        <property type="entry name" value="Peptidase_C48_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47764">
        <property type="entry name" value="UBIQUITIN-LIKE-SPECIFIC PROTEASE 2B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02902">
        <property type="entry name" value="Peptidase_C48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50600">
        <property type="entry name" value="ULP_PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like protease family profile" evidence="6">
        <location>
            <begin position="160"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="5">
        <location>
            <begin position="537"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="479"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="651"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="651"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1128" mass="127629" checksum="A9D6D84E5800C389" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB80</accession>
    <name>A0A8T0IB80_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ABM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G191200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB80"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36986:SF1">
        <property type="entry name" value="UPF0643 PROTEIN PB2B2.08"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="199" mass="22726" checksum="4FE2654EB85051E0" modified="2022-10-12" version="1">MLMYVVIPRAFCESCLGTLYFICCSDLKMPEQGGEGGMFISVQEVVPVYTVKQLAANQYAYTDPLTTPVEKCFDWNRELKDLVTFHGREFYLVVFRSIRKSSADNEMLYNADAAAQEEARLSGGLLKYWYGILNERRECLAMCIWASREDAVKAIHKPAHRVAMKLTSAMYDMYTLERYSLKIDENLVPTFTLLGSMSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IB90</accession>
    <name>A0A8T0IB90_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G214600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IB90"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="87" mass="9544" checksum="1FCBF9960A6CB8CC" modified="2022-10-12" version="1">MALNDFFNFSPLSFSIHGYNCISGENTASLDNTPFSLRRVSTNVLRYSTKNGKSSFDANIVSGSNLEAPGISLLKVRQLVPMQVNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICQ7</accession>
    <name>A0A8T0ICQ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histone H2A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G158500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone H2A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICQ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000786">
        <property type="term" value="C:nucleosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.20.10:FF:000165">
        <property type="entry name" value="Histone H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002119">
        <property type="entry name" value="Histone_H2A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23430">
        <property type="entry name" value="HISTONE H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00620">
        <property type="entry name" value="HISTONEH2A"/>
    </dbReference>
    <dbReference type="SMART" id="SM00414">
        <property type="entry name" value="H2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0158">Chromosome</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0544">Nucleosome core</keyword>
    <keyword evidence="1" id="KW-0539">Nucleus</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="9253" checksum="416DA711B7548568" modified="2022-10-12" version="1">MDYGATVEVSKGSRASKGPGHIARLGSGGRGRRKSSKSVSRSHKAGLQFRVGRIARYLKGGKYAERVGAGAAVYLAAVLEYLAAEVMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICV7</accession>
    <name>A0A8T0ICV7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycoside hydrolase family 19 catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_4G165500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICV7"/>
    <dbReference type="OrthoDB" id="5985073at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00325">
        <property type="entry name" value="chitinase_GH19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.20.10">
        <property type="entry name" value="Endochitinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016283">
        <property type="entry name" value="Glyco_hydro_19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595:SF96">
        <property type="entry name" value="CHITINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22595">
        <property type="entry name" value="CHITINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001060">
        <property type="entry name" value="Endochitinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="Lysozyme-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035812753" description="Glycoside hydrolase family 19 catalytic domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 19 catalytic" evidence="5">
        <location>
            <begin position="46"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="138"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="3">
        <location>
            <begin position="245"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001060-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0580333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="292" mass="32035" checksum="DE28CA0F36BA1E1B" modified="2022-10-12" version="1">MARVVVVVVIVLVLGLHMLGLGAEGLACTKEMKSGSCNKTMSDLFTVEMFEGMFKHRNDRVAHAPGFWSYGSFLSAAKMFEKAGFGSVGGDDVQKRELAAFFAHVAHETSCGWPGSKDGPYAWGLCYNQELSPGDIFCTEDLLYPCAPGATYYGRGALPLYWNYNYGLTGAALNQDLLHHPDILANNETIAWQAAIWYWMTPAKTRPSPHQVMVGKWIPSKNDTLAKRQPGFGMTINIKASNGECGHGDDTRMQDRIGHYLYFLQGYFGGLDPGLHVDCGSQGVVLLEYASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID46</accession>
    <name>A0A8T0ID46_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G203700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID46"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12585" checksum="50D9146B5F97C1F8" modified="2022-10-12" version="1">MAPLALPRPCLRHRHSRGRTDAIRRHRLPRSCQSASELACYRTHRSSNCFRGDSTGSPSRLNIPTSCYDSLRVPIVGRGHDENNVRDLCPTVARPGSGGSPFDGYMVNTLVIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDZ0</accession>
    <name>A0A8T0IDZ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thiaminase-2/PQQC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_4G233300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDZ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd19357">
        <property type="entry name" value="TenA_E_At3g16990-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.910.10">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016084">
        <property type="entry name" value="Haem_Oase-like_multi-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026285">
        <property type="entry name" value="TenA_E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004305">
        <property type="entry name" value="Thiaminase-2/PQQC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050967">
        <property type="entry name" value="Thiamine_Salvage_TenA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198:SF5">
        <property type="entry name" value="BIFUNCTIONAL TENA-E PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43198">
        <property type="entry name" value="BIFUNCTIONAL TH2 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03070">
        <property type="entry name" value="TENA_THI-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003170">
        <property type="entry name" value="Pet18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48613">
        <property type="entry name" value="Heme oxygenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiaminase-2/PQQC" evidence="3">
        <location>
            <begin position="17"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR003170-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR003170-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0581215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="225" mass="26153" checksum="D5FC84C1D94D559C" modified="2022-10-12" version="1">MSTISESRSFTTDWLHQNHELYTAATNHTFIASIRDGTIDVINFKHWMEQDYHFVREFVRFVASVLLKVPRDSPEQDADVILGGLTALESEISWFRKEANFWQIFLEKVTPLESNKEYCEFLKELEGTETPYPVAVVAFWMIELVYNASFMSCLEEGSKTPFELLSTVKRWGSLEFHQYVHSLQQLADKALENVSEAELKKAHEVCVRILELEIKFWDMATIQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IF43</accession>
    <name>A0A8T0IF43_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coiled-coil SMC6 And NSE5 INteracting (CANIN) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G226900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IF43"/>
    <dbReference type="OrthoDB" id="674980at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044276">
        <property type="entry name" value="CANIN_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37212">
        <property type="entry name" value="ACTIN PROTEIN 2/3 COMPLEX SUBUNIT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37212:SF2">
        <property type="entry name" value="ACTIN PROTEIN 2_3 COMPLEX SUBUNIT-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14816">
        <property type="entry name" value="CANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coiled-coil SMC6 And NSE5 INteracting (CANIN)" evidence="2">
        <location>
            <begin position="150"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0581128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="481" mass="54637" checksum="959477C0486D3295" modified="2022-10-12" version="1">MMEVESVLPEDDDEDWMRATPASQEVEEDEGAKKRQKKVLTLDDLLKAERKETVRQLKGKKSKKQLAKLNAKSHLYSSSDEESEKDARKKAMIMTLERQVPVAEEVEPEYGAPVFAARLEFPSLTRGGAPSLQRALQASKEAGRETTLEELARSGFLRAWAFGANRCDESTLRWAYHQMAYAIDDSLERSACKFLCDLVSRIDMDTRAPFQMDWLPTLVDVKQTLVVYGYKEGSKDGKILDFSSGNIERRPPKNLRSVLEFIATCFNTRDMQPYYSVVDVEALLVIMLHLTLERGLLEILDKVQDCILALIRYFSPEDWGEVCLHAAASISGLTKRPHNGIFILGVLSGLGNRSMDLQKRLALHELAKLVPQKKSISTAREVAASFEKINLKAKEIDFVKIYYQLVIADIFLWCNEGLSDEIARLKWLKFLGSCSRKISIGDDRAFATKLRNTACFFIVKYEHDGHDREDSPANFVEEDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFS0</accession>
    <name>A0A8T0IFS0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="8">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_4G243900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>N(6)-[(R)-lipoyl]-L-lysyl-[protein] + pyruvate + H(+) = N(6)-[(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Tetramer of 2 alpha and 2 beta subunits.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="8"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFS0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:pyruvate decarboxylation to acetyl-CoA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02000">
        <property type="entry name" value="TPP_E1_PDC_ADC_BCADC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.970:FF:000013">
        <property type="entry name" value="Pyruvate dehydrogenase E1 component subunit alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.970">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050642">
        <property type="entry name" value="PDH_E1_Alpha_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF60">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="Thiamin diphosphate-binding fold (THDP-binding)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Dehydrogenase E1 component" evidence="10">
        <location>
            <begin position="89"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00051231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0581343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="465" mass="51701" checksum="9C8CC6AE36A8F7C8" modified="2022-10-12" version="1">MAMHLWRRAWNVLRQTPGGPVSGAVTRAQAAVSSTQNPPSVTAAASASRSFAGDAKIAYETPAFKGHKTDVPTTKVETSGKELMGFFRTMFLMRRMEIAADAMYKQKFVRGFCHLYDGQEAVCVGMEAALNEKDCIITSYRDHCTHVGRGGTVYEVFAELMGRKDGCSLGKGGSMHMYNKKGGFFGGNGIVGAQTALGAGLAFAQKYLKVEGVTMAMYGDGAANQGQLFEAMNISALWDLPVIYVCENNHYGMGTAEWRSAKSPCYYKRGDYIPGMQVDGMDCMAVKQAVKFAKAYALKKGPFVLEFDTYRYHGHSMSDPGSTYRTRDEIKAIREGRDCIEKIRRIILKHKVATEKELKEIEKGAKKEVEDALAKAKNAPLPDPPELFTNIFVKSCGALVRLSPIACKRTLYIKIVIHDWLYRCFWSMDMNALEYFILVSLSLAFLYFAEVVVLNCSRMELIARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHD4</accession>
    <name>A0A8T0IHD4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G114200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHD4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009873">
        <property type="term" value="P:ethylene-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044808">
        <property type="entry name" value="ERF_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31190">
        <property type="entry name" value="DNA-BINDING DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31190:SF167">
        <property type="entry name" value="ETHYLENE-RESPONSIVE TRANSCRIPTION FACTOR ERF112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="178"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="47"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="97"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="234"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="388"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0583160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="437" mass="48286" checksum="BA3C622C0C80BB06" modified="2022-10-12" version="1">MLLCRPSMTDPSEYTTFPEMYRPPDPMSRRSMPNPVSEVSMMVHALTQAADPGSSSSSYGTHWPDTSRMMSSTQGPYSEYIDISRASAAPWRPVHDWNEQSQHSSSPSNTYDQNSPESGRYGEFSLHHHHSSSPPRTRESPMQRSGYELSEGFTDSRAAANENATLCNSPTEPAKKRKYRGVRQRPWGKWAAEIRDPKKAARVWLGTYDTAEEAAQAYDKAAKEFRGLRAKLNFPDGVHQGIGSSSRVSRRSASTPATESSVPQPPIIESHHRSLPNPSSWSNSSSHPPSSTGFSESAPATFTTAPQYSYSEPYYNQPWQDQGQHINVYPSDSHGYGQPLYSSTVDAYASTSAPFSVPSNSNSSEFDSYYMNRGESSAYGSQYSSYRDHLGNSSAPELSYEQIFEQQGDDGSGGSSGWQAPGNLSPGYDFPFYGRHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKD6</accession>
    <name>A0A8T0IKD6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G126500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051707">
        <property type="term" value="P:response to other organism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="3">
        <location>
            <begin position="14"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0583317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1030" mass="114766" checksum="9B0DD4ACBAE4CD33" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILF2</accession>
    <name>A0A8T0ILF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Coatomer subunit zeta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_3G153900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 12">Golgi apparatus membrane</location>
            <topology evidence="1 12">Peripheral membrane protein</topology>
            <orientation evidence="1 12">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Cytoplasmic vesicle</location>
            <location evidence="12">COPI-coated vesicle membrane</location>
            <topology evidence="12">Peripheral membrane protein</topology>
            <orientation evidence="12">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the adaptor complexes small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILF2"/>
    <dbReference type="OrthoDB" id="10249988at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030126">
        <property type="term" value="C:COPI vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006891">
        <property type="term" value="P:intra-Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006890">
        <property type="term" value="P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14829">
        <property type="entry name" value="Zeta-COP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.60:FF:000014">
        <property type="entry name" value="Coatomer subunit zeta-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022775">
        <property type="entry name" value="AP_mu_sigma_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039652">
        <property type="entry name" value="Coatomer_zeta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011012">
        <property type="entry name" value="Longin-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043:SF0">
        <property type="entry name" value="COATOMER SUBUNIT ZETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11043">
        <property type="entry name" value="ZETA-COAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01217">
        <property type="entry name" value="Clat_adaptor_s"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64356">
        <property type="entry name" value="SNARE-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 12" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6 12" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8 12" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AP complex mu/sigma subunit" evidence="13">
        <location>
            <begin position="8"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00045555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0583676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="178" mass="19563" checksum="95D7C04400DE72AC" modified="2022-10-12" version="1">MDASTPLIKNVLLLDGEGKRVAVKYYSDDWPTLAAKLAFEKSVFTKTQRTSARSEAEIGMFDGYIVVYKFISDLHFYVTGGEDENELIVATVLQGFFDAVGLLLRNNVEKKSVLENLDLVLLCLDEIIDGGIILESDANTIASRVAMRGADSDVPLSEQTISQALATAKEHFARSLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILI7</accession>
    <name>A0A8T0ILI7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G160400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILI7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="16952" checksum="7D6BB22B7A7CEAA3" modified="2022-10-12" version="1">MAVEAEEIVEAEDHHPAKEEVGPASGSPQDPVAVSSRPSEAPVRLLREDDVRVREQNRRRRHPMRHRPCLPDVPHASARPNGLSRMISLLPSWSEPASHGLQFHLSASCGYGCGASIELWRWRWRWVASSPNMWLYGRLDKLFPFLLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ILL3</accession>
    <name>A0A8T0ILL3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Splicing factor YJU2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G226200</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CWC16 family. YJU2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ILL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000349">
        <property type="term" value="P:generation of catalytic spliceosome for first transesterification step"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03226">
        <property type="entry name" value="YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007590">
        <property type="entry name" value="Saf4/Yju2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043701">
        <property type="entry name" value="Yju2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12111:SF1">
        <property type="entry name" value="SPLICING FACTOR YJU2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04502">
        <property type="entry name" value="Saf4_Yju2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="5 8" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="225"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0584664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="357" mass="40110" checksum="047FD547209B76C7" modified="2022-10-12" version="1">MGERKVLNKYYPPDFDPAKIPRRKQPKNQQIKVRMMLPMSIRCNTCGNYIYKGTKFNSRKEDCEGETYLGIQIFRFYFKCSKCSAELTMKTDPQNSDYIMEAGASRNYEPWRATDEATDEAVKKRETEELGDAMKALENRTLDSKQEMDIMAALDEMKSMRSRHATVAVEDMMAALRRTASEREKAMEEQDEAVLKSVVFQNSSKFVRRIDDDELEDDGDDYFDEDHRSKTSEGGDFSKRRKIQAETLVKKEGEVKAPVQAAGVLVNHVLETEAKGSNGATKAGPSFAVRLKPVAFNIKPKVVGMVSSSTVKQVKEEAVTDQAARPLEATVKQEIQEPSSAVTSLGLAYGSSEDDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM44</accession>
    <name>A0A8T0IM44_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G173500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM44"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="131" mass="14594" checksum="69E66E85A214B997" modified="2022-10-12" version="1">MISSHISTTRWQQLNDNEGDDGRNCMRRGLDMTTLINLAMCCNTCVCVTMCEHTPNRSGLKVHRYRSGLGESLDQRSSVYYSTWLSCNSANIREFIPVSDAGVSVCSASSPPFTNQPWPFLLRIGARLDGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IM50</accession>
    <name>A0A8T0IM50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G203700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IM50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035780879" evidence="1">
        <location>
            <begin position="18"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11407" checksum="4F403612FA320F3D" modified="2022-10-12" version="1">MEIVAHMLLPLSLLTSARDWLSTSRSLHMLNARMAQKQTSMLNLVQVVSIHFRLVYYKPWQMCSSAAVNDFFALRTTEPKAPSLCSDFPVGFGLGYALAWQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IP80</accession>
    <name>A0A8T0IP80_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G021800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IP80"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035855732" evidence="1">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="10931" checksum="F800D75AB95F7C8B" modified="2022-10-12" version="1">MMATSYTKWMLTAMVMATLFSSQWAESSRILSDEITTLDHSSGRSLLQTCWPGTRLNCGSDTQVECEVGGVGGCDCLAMEGCLPEVSGCFIVVNGVATTSCGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITB6</accession>
    <name>A0A8T0ITB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">POPLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G131200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005655">
        <property type="term" value="C:nucleolar ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000172">
        <property type="term" value="C:ribonuclease MRP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039182">
        <property type="entry name" value="Pop1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055079">
        <property type="entry name" value="POP1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012590">
        <property type="entry name" value="POPLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731">
        <property type="entry name" value="RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22731:SF3">
        <property type="entry name" value="RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22770">
        <property type="entry name" value="POP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08170">
        <property type="entry name" value="POPLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POPLD" evidence="2">
        <location>
            <begin position="358"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="POP1 C-terminal" evidence="3">
        <location>
            <begin position="741"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="480"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="487"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="599"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="810"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0586964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="909" mass="99062" checksum="7617A7FB38A66AAB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITM1</accession>
    <name>A0A8T0ITM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF155 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G064300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RMD1/sif2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003734">
        <property type="entry name" value="DUF155"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051624">
        <property type="entry name" value="RMD1/Sad1-interacting"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255:SF6">
        <property type="entry name" value="PROTEIN RETARDED ROOT GROWTH-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16255">
        <property type="entry name" value="REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02582">
        <property type="entry name" value="DUF155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF155" evidence="3">
        <location>
            <begin position="284"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="122"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0586101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="506" mass="58661" checksum="45156BE856074DAD" modified="2022-10-12" version="1">MRAATQWRHLQQLGRAFTANPFLPASSEAYLINSIFASWSKSVEQLWKSSTTLAQGIDPQRNSIGKKLHSSFRSGHVRNYSSSDQEFGAQPHVSGQRNLYSVNPNQIWKLRFRLTPVRMQGSTAHSREPEYWDSSETTQFNEEGLPADQSRPLREREWDHDEDEDLTRDRKVRNDVHGMKLSRDDDGIEWGQQHVRVREYENRQRASLSPNPPPQFEQDDVYIPVKACYISRNVDLKRLSETFLDVTASRNNLIIRFANRPADGEPTSNRPGFAEISRSQERYMVAFQYGSIVFFNFGDDEEEEALSAVRKFCTDEFRETRKDDYGVLVRPTLNEWSQGGQDRIMLRMLDTDNIRVISSILGQSIALDHYAKKVDEMVNTFSELNRGMEKTGTFTMTRKSLFQLVAAANTTLADVILRLGLLERSDAAWKDANYAQIWEYLRDDFELDERFESLDFKLNIIQHNVRFFLEILQNRKSDTLEWIIILLITGEICVGVYQILLETNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV48</accession>
    <name>A0A8T0IV48_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_2G120800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV48"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044837">
        <property type="entry name" value="REM16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391:SF106">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS01G0723500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS11G0197600-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="7">
        <location>
            <begin position="38"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="143"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="226"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="551"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="199"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="242"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0586829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="642" mass="71151" checksum="1E2BCB07F3B55972" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWB4</accession>
    <name>A0A8T0IWB4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G150200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWB4"/>
    <dbReference type="OrthoDB" id="523796at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36052:SF1">
        <property type="entry name" value="EXCITATORY AMINO ACID TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9321" checksum="16A161ED0AC99E24" modified="2022-10-12" version="1">MVATATMVGAIMGLSVQFYSNGVRKLPLMRHPWEHLLAMGLGAGFGNAVAKWEVRLEEDLDKKLSEVKTANNKRYIGTMRAVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IWJ5</accession>
    <name>A0A8T0IWJ5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G112300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IWJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11211" checksum="9C7679DEFEEFAF8D" modified="2022-10-12" version="1">MTCRSGKAVKLIVRSLLRPMDAAMEWTFWMVFLTAILGAVIAALLSDVLKELLWKLIASVRKTLGYETPDLQTIITNSIIDAFRNSGTEGIPRGIADVCSNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXV1</accession>
    <name>A0A8T0IXV1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G148700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXV1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="WD40"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32161">
        <property type="entry name" value="DPP6 N-TERMINAL DOMAIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32161:SF26">
        <property type="entry name" value="OS03G0403400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82171">
        <property type="entry name" value="DPP6 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="726" mass="80105" checksum="9E49D3D8C539F4B8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYH6</accession>
    <name>A0A8T0IYH6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G192200</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Secreted</location>
            <location evidence="1 12">Extracellular space</location>
            <location evidence="1 12">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYH6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010497">
        <property type="term" value="P:plasmodesmata-mediated intercellular transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000280">
        <property type="term" value="P:regulation of root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.10:FF:000025">
        <property type="entry name" value="germin-like protein subfamily 2 member 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019780">
        <property type="entry name" value="Germin_Mn-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00725">
        <property type="entry name" value="GERMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0052">Apoplast</keyword>
    <keyword evidence="7 11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8 9 12" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 9 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0964">Secreted</keyword>
    <keyword evidence="6 12" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="12">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035969761" description="Germin-like protein" evidence="12">
        <location>
            <begin position="29"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="13">
        <location>
            <begin position="64"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="11">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0587798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="220" mass="23159" checksum="9C98B5241C8815A9" modified="2022-10-12" version="1">METVKRIVFLALLVQASLLPMLAFAADADPIQDFCVADGTSKITVNGLVCKSPADVKVSDFLFRGLNKPGNTNNPTANAVTPVFAAQLPGLNTLGISMARLDFAQGGVNVPHTHPRATEILTVLQGELYVGFVSTGNQLFATTLYAGDVFVFPKGLVHFQLNVGKGAAVAIAALSSQNPGVQQVGRALFGSSPPVGDEVLEKAFGINQKAVQHIRNNFKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYP0</accession>
    <name>A0A8T0IYP0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">sphingosine kinase</fullName>
            <ecNumber evidence="7">2.7.1.91</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_2G195200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Vacuole membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.91" evidence="7"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYP0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005774">
        <property type="term" value="C:vacuolar membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008481">
        <property type="term" value="F:sphingosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046512">
        <property type="term" value="P:sphingosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10330:FF:000005">
        <property type="entry name" value="Sphingosine kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="entry name" value="Probable inorganic polyphosphate/atp-NAD kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050187">
        <property type="entry name" value="Lipid_Phosphate_FormReg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358:SF31">
        <property type="entry name" value="ACYLGLYCEROL KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12358">
        <property type="entry name" value="SPHINGOSINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="NAD kinase/diacylglycerol kinase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="8">
        <location>
            <begin position="103"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00044037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0587836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="483" mass="53082" checksum="7A4D24BFD74F46D4" modified="2022-10-12" version="1">MGEVVTETAVLEGRRVVVTLDGEGLLQWRGDREGEVLVRSDLIGFRSVGSSVHLYTFKMVESMAMCGKGSLGRRRKDIVMEFDNEAAIKLFCDAIHKILEESGRPKRLLVIVNPFGGDKAGRRVYTSSVEPLLQAAGIAITMQETKYQRHGKDLAKSFDVSQFDGIVCVSGDGVLVEVLNGLLERPDWKAAIKMPIGIIPAGTSNGMAKSLLDHVGEPCDAASATFLVIRGQKQPLDVATAKQANVKFHSILMMAWGLVADVDFESEKFRWMGALRLDVYTLIRICSLRKYVGHIYYIPAPGYEGTGTPFTEDLEETALLKSHEGDSDRSLKKNGYHGALHELTKSGQWRHMEGPFINVWLNNVPFVGETVKSAPHAKFSDGCLDLIIMKDCPRWTLLNLLLKLQTGGHIKSKYVEYLKVKAFRLDPAGRYGSDIQGGYIDLDGEILARGRGTVGDGSSDIMTYGPPVDVTVDRGLATIFCPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZM5</accession>
    <name>A0A8T0IZM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Acyl-[acyl-carrier-protein] desaturase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_1G000700</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="14">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Plastid</location>
            <location evidence="2">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fatty acid desaturase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045300">
        <property type="term" value="F:stearoyl-[ACP] desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01050">
        <property type="entry name" value="Acyl_ACP_Desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.620.20:FF:000002">
        <property type="entry name" value="Stearoyl-[acyl-carrier-protein] 9-desaturase, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="entry name" value="Ribonucleotide Reductase, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005067">
        <property type="entry name" value="Fatty_acid_desaturase-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155">
        <property type="entry name" value="ACYL- ACYL-CARRIER-PROTEIN DESATURASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155:SF36">
        <property type="entry name" value="ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03405">
        <property type="entry name" value="FA_desaturase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000346">
        <property type="entry name" value="Dlt9_acylACP_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="Ferritin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="13" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="11 14" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0934">Plastid</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0809">Transit peptide</keyword>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="15">
        <location>
            <begin position="12"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000346-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0589170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="419" mass="48270" checksum="52756E6B95182119" modified="2022-10-12" version="1">MASKGLLESQMRVATQPTPSFSGRRRLEEKPTSSVASLRRWKPLKVVMTSSPPRERQVMRDTTLHDHKALTPYQPWTRHEPEQVPVEKLEVIASLDSWAQENLLPLLKPVSKSWQPQDFLPDASSESFFDEVRELQSRARELPDDYLVCLVGDMITEEALPTYQTMFNTFEGVRDKTGCSPTPWGVWIRAWTAEENRHGDLLNRYLYLSGRVDMCMVERTTQYLIGSGMEPHIDQNPYNGFIYTSFQERATFISHGNTARHAKQLGEHKLATICGIIASDEKRHEIAYSRIVSKLFELDPSGTMLSFQEMMKKKITMPAHLMYDGDNDHLFDDYSSVAQRCGVYTAQDYASIMEHLIDLWNVKSLTGLSSEAQKAQEFVCKLPARIHRLAERTQRRARGEVPRRRAFSWIHNKEVDLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZU1</accession>
    <name>A0A8T0IZU1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_2G231000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZU1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186:SF38">
        <property type="entry name" value="ANKYRIN REPEAT FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24186">
        <property type="entry name" value="PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="740"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="817"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="9">
        <location>
            <begin position="697"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0588276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="861" mass="95733" checksum="BF53712FA7779B44" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZU8</accession>
    <name>A0A8T0IZU8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G240900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0588409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11673" checksum="3B9F5B68DD6FEA85" modified="2022-10-12" version="1">MMVLLQKSHQDHRVHLLNMVKWSSLHTMQMVDAEAKILTRTWCRCIVRCCEEGCGVNRSSTSLEASKDLSTQYPVKRMVNFMSVQFISPRLETHCRGKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J006</accession>
    <name>A0A8T0J006_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G205000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J006"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47747:SF2">
        <property type="entry name" value="RIBONUCLEASE P PROTEIN SUBUNIT P38-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="866"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="107"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="185"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="303"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="445"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="653"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="758"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="886"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1209" mass="137214" checksum="EF51F3A5BC1EA72E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0T9</accession>
    <name>A0A8T0J0T9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G030900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0T9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035859124" evidence="1">
        <location>
            <begin position="21"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="53" mass="5537" checksum="387CA66649CB527C" modified="2022-10-12" version="1">MDAVLLVPLLLGYIPSLDSALPLPCGAGRSCRKIGPTMIALPDDNACRTDPTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4L2</accession>
    <name>A0A8T0J4L2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G109200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4L2"/>
    <dbReference type="OrthoDB" id="10592571at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="396" mass="44209" checksum="56A8FD5AEE90BFF4" modified="2022-10-12" version="1">MPEKANHSGFDKCNSCASTSDGPELGPLSTVSHPQVCCLFKVARQGQSAPFLNEGSQKRYDGFCDYCPSRKSSMEFHAGPVDRPPPSSSDAPQAGIVALATGCEAAPEVTRSPSRKRKKIEPRKREGFKNLTLEWRPPKFKAKIWFGTYSKDEIERARDAVNYYLGRNEAYFLDDSPRIFAERPLMGIRFEDLLPSCDQVIDKQILRERSLMGIKFEDFLPSCDQVMDTLPAYVIYGRQVKEVIHSVLGKQKKSAERKSKCKESQFLLKEAPQKLHIYDPIVPSASGSPTSSVSQREDCDHSSEANSQLSSSYPMVLPPPSFTQDDEELTALLLSTTQIHLDELPHNHWGDGQLSLNEMFALPTSGDGESSTMEDIGYSTALWDYFPNEGPSFPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J561</accession>
    <name>A0A8T0J561_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G146200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J561"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056555">
        <property type="entry name" value="NFD4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010658">
        <property type="entry name" value="Nodulin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF154">
        <property type="entry name" value="OS04G0502800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23262">
        <property type="entry name" value="NFD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06813">
        <property type="entry name" value="Nodulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="478"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="514"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="566"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Nodulin-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="NFD4 C-terminal" evidence="8">
        <location>
            <begin position="380"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0591060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="612" mass="66761" checksum="78F7CC2DDC9F5A46" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7C2</accession>
    <name>A0A8T0J7C2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G151400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7C2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="77" mass="8538" checksum="701360E9DA39B11E" modified="2022-10-12" version="1">MAAMEGRCVHSSTGTPPLRPGRCWRSPFAGDWLPWNRALGLWSYVMEYSFLPPLGIEFLVVNRNGIHAQGESNSCGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J7U3</accession>
    <name>A0A8T0J7U3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G196800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endosome</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J7U3"/>
    <dbReference type="OrthoDB" id="5592979at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000815">
        <property type="term" value="C:ESCRT III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005771">
        <property type="term" value="C:multivesicular body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032511">
        <property type="term" value="P:late endosome to vacuole transport via multivesicular body sorting pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006900">
        <property type="term" value="P:vesicle budding from membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.250.1710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1060">
        <property type="entry name" value="ESAT-6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005024">
        <property type="entry name" value="Snf7_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761">
        <property type="entry name" value="CHARGED MULTIVESICULAR BODY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22761:SF10">
        <property type="entry name" value="GH13992P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03357">
        <property type="entry name" value="Snf7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0967">Endosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="175"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="122"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0591727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="219" mass="24739" checksum="2C9359151E79A0E7" modified="2022-10-12" version="1">MFSRIFGKPKEEVSTLSTLDKLNETLEMLEKKEKVLQKKIAMEIEKAKEFTRLKNKRAAIQCLKRKKLYEVQVEQLGNFQLRIHDQMIMLEGAKATTETVDALRSGASAMKAIQKATNIDDVDKTMDEINEQTENMKQIQEALSTPIGTAADIDEDELEAELEDLEGAELEEQLIRPSTHQLPPAAEKYRPTPVPATKKPVQNTEEEDELAALQAEMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAU8</accession>
    <name>A0A8T0JAU8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase II C-terminal domain phosphatase-like</fullName>
            <ecNumber evidence="6">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_1G300500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This promotes the activity of RNA polymerase II.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008420">
        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd07521">
        <property type="entry name" value="HAD_FCP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011947">
        <property type="entry name" value="FCP1_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02250">
        <property type="entry name" value="FCP1_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="8">
        <location>
            <begin position="192"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0593040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="597" mass="65508" checksum="784663F755E46032" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JB35</accession>
    <name>A0A8T0JB35_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phytocyanin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G241500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JB35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04216">
        <property type="entry name" value="Phytocyanin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.420:FF:000034">
        <property type="entry name" value="Cupredoxin superfamily protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039391">
        <property type="entry name" value="Phytocyanin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003245">
        <property type="entry name" value="Phytocyanin_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021">
        <property type="entry name" value="BLUE COPPER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33021:SF193">
        <property type="entry name" value="OS06G0218600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02298">
        <property type="entry name" value="Cu_bind_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51485">
        <property type="entry name" value="PHYTOCYANIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Phytocyanin" evidence="5">
        <location>
            <begin position="48"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="161"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="251"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0592312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="38948" checksum="2C22A9E604209241" modified="2022-10-12" version="1">MDARAATEALNPRGCNKPLRMKLRSSVALMLVFAIILPPNVQLAMAKPTYVVGDGGNGWSFAPYASYFSDWATQFNIFPGDMLNFKYDPAEHNVLQVNQSDYSTCNTSHAIQQYKSGDDVVPLPRPGTYYFICGFENHCSEAGMLMKVSVVNRPGYPPYVDPPPPPSPHPPPPPPPHSPPPPPPSPPPPPPHHPPPPPPHHPPPPPQLPPPPPPSPPPPPSLPPATSPSNSPSSAPASSPASSPASSPASSPSPPPEPQGESPPFPPPSMLPPAPAGSLMSNASSPPRASSRTHDHRTHDHQFVMNHQPVPAISETLTAVITPCPSARLAPDAAQSDPGAASANSRPSVSSMSMSVVAAVVMAAGAVVFGGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC13</accession>
    <name>A0A8T0JC13_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="4 11">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ADP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G236800</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="4 11"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC13"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02508">
        <property type="entry name" value="ADP_Glucose_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04651">
        <property type="entry name" value="LbH_G1P_AT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000030">
        <property type="entry name" value="Glucose-1-phosphate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002772">
        <property type="entry name" value="PRK02862.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523:SF12">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE LARGE SUBUNIT 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25247">
        <property type="entry name" value="LbH_GLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="12">
        <location>
            <begin position="112"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0592251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="543" mass="59896" checksum="8607F5D11F162FD7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC92</accession>
    <name>A0A8T0JC92_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G304400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC92"/>
    <dbReference type="OrthoDB" id="408373at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080030">
        <property type="term" value="F:methyl indole-3-acetate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080032">
        <property type="term" value="F:methyl jasmonate esterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045889">
        <property type="entry name" value="MES/HNL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10992:SF1086">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10992">
        <property type="entry name" value="METHYLESTERASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035945269" description="AB hydrolase-1 domain-containing protein" evidence="1">
        <location>
            <begin position="32"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="60"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0593085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="304" mass="32508" checksum="1A0A6A52BD9A50A8" modified="2022-10-12" version="1">MASTGISSRAGICGLAILAILLSPQIAGAWADGGDDRNSGPNCSNSVCQNQNSYAPKHFILVHGMGGGAWFWFEIITLLEHYGFTATAVDLTSHGINKAIADDVTTVAQYAKPLTDAIENATGQVILVGHSLGGGLIAYASELYPTKVSKAIYLSAVTPSYNQSMFGAFPADTFPNLITPGYLTLNFRRGTSTPSSATVNVNALDKFYMSETPKRYVNLAKLLFTDTPYVPGTEVLPLSPAKFGTVRRFYIRTGKDKGVSPADQDAMIAANPPEKVFCMPNGDHAVFFSAPMELYRLLTCISGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDE4</accession>
    <name>A0A8T0JDE4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Alkaline/neutral invertase</fullName>
            <ecNumber evidence="6">3.2.1.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_1G333500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Invertase that cleaves sucrose into glucose and fructose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.</text>
            <dbReference type="EC" id="3.2.1.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the glycosyl hydrolase 100 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.26" evidence="6"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDE4"/>
    <dbReference type="OrthoDB" id="585877at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033926">
        <property type="term" value="F:endo-alpha-N-acetylgalactosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004575">
        <property type="term" value="F:sucrose alpha-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005987">
        <property type="term" value="P:sucrose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.50.10.10:FF:000001">
        <property type="entry name" value="probable alkaline/neutral invertase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024746">
        <property type="entry name" value="Glyco_hydro_100"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31916">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31916:SF59">
        <property type="entry name" value="CYTOSOLIC INVERTASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12899">
        <property type="entry name" value="Glyco_hydro_100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0593485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="577" mass="65550" checksum="3AAEEDBE7885796D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JEV6</accession>
    <name>A0A8T0JEV6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G329300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JEV6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="113" mass="12547" checksum="DF3BE28232D39563" modified="2022-10-12" version="1">MFASSSSLPSNSLSLEIGQLCTSPPLLQIKATAINAYDMHFHLCPLQQPIAADMRRGKLKIPCHQNTQKPTNRNKKQHSHNFLNLIAIAQTQVQSISTETHQPFPMVEQSSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G440</accession>
    <name>A0A8T0G440_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Iron-binding zinc finger CDGSH type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G030400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G440"/>
    <dbReference type="OrthoDB" id="449252at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010506">
        <property type="term" value="P:regulation of autophagy"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.5.90:FF:000001">
        <property type="entry name" value="CDGSH iron-sulfur domain-containing protein 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="entry name" value="CDGSH iron-sulfur domain, mitoNEET-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045131">
        <property type="entry name" value="CISD1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13680:SF5">
        <property type="entry name" value="CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iron-binding zinc finger CDGSH type" evidence="7">
        <location>
            <begin position="58"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="17"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0553675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="11379" checksum="7D41F9EDD10F894D" modified="2022-10-12" version="1">MAALASASALFRGAALSVSAPAGSSRRARTGVRAEAEASTSTSAAAPINPSIRKESDKVVDTVQVAELSKPLVAYCRCWRSETFPLCNGAHVKHNKETGDNVGPLLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6X0</accession>
    <name>A0A8T0G6X0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G025900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6X0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11732">
        <property type="entry name" value="ALDO/KETO REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0553618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="353" mass="40200" checksum="67074B1EA697BB8A" modified="2022-10-12" version="1">MDYFTLNNNVKIPAIGLGLWDIEKELCKTVVAIALDVGYRHFDCAHWYGNDKEVGEVLFEAFEKGLSRNEIFVTSKFWCTTTSANHVQEAINTSLKNLKLDYLDLCLVHWPEPYSFGTIDASDPPSRHMQSRVKDDTSKFIRQLKTIWQVMESLLQKGILRAIGLSNFGRAQIEEILKFAKIVPAVHQMELHPFWRQDDFVKFCQSKGIHVSAHTPLGVPGKDVARGAEETSIAQRSTSIHAPMLRASVVSEIAKRLNRTPAQVILRWGVQRGTSVLPRSLLEERIRANYDILNWSLSNDDWIKLNSIEPQIRLVDGTHASADYDQLQSTKLDMMALKQNLMKMLIGMEMTFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G6Y0</accession>
    <name>A0A8T0G6Y0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G138900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G6Y0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0555036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="94" mass="10542" checksum="B1E488F1500FC83C" modified="2022-10-12" version="1">MTPRVVRNPARIVTARKPRMLSRLQVTLPYATFLQQSFVKTLKSLLRNCPSLLQAHPILPPPYTSGGGWVPSLTFDFTEFYLRVGVGWRGVSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7M2</accession>
    <name>A0A8T0G7M2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_12G087300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7M2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01681">
        <property type="entry name" value="aeEF2_snRNP_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04096">
        <property type="entry name" value="eEF2_snRNP_like_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01885">
        <property type="entry name" value="EF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16268">
        <property type="entry name" value="EF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16261">
        <property type="entry name" value="EF2_snRNP_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000010">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000006">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000003">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000002">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000058">
        <property type="entry name" value="Translation elongation factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF10">
        <property type="entry name" value="EUKARYOTIC TRANSLATION ELONGATION FACTOR 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="17"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0554384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="844" mass="93754" checksum="846E3E50BE924D6B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G935</accession>
    <name>A0A8T0G935_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G134500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G935"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6148" checksum="51A4A4A588875049" modified="2022-10-12" version="1">MSAQLFTVGIVISFRKTSSGISLLAQCTPYDASGNQLLLRRTWHPSPNIYLSDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9J3</accession>
    <name>A0A8T0G9J3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Legumain prodomain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_12G098600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9J3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004197">
        <property type="term" value="F:cysteine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006624">
        <property type="term" value="P:vacuolar protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21115">
        <property type="entry name" value="legumain_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.132.130:FF:000001">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1460:FF:000005">
        <property type="entry name" value="Vacuolar-processing enzyme beta-isozyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043577">
        <property type="entry name" value="AE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048501">
        <property type="entry name" value="Legum_prodom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046427">
        <property type="entry name" value="Legumain_prodom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001096">
        <property type="entry name" value="Peptidase_C13"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000">
        <property type="entry name" value="HEMOGLOBINASE FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12000:SF42">
        <property type="entry name" value="LEGUMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20985">
        <property type="entry name" value="Legum_prodom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01650">
        <property type="entry name" value="Peptidase_C13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500139">
        <property type="entry name" value="AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019663">
        <property type="entry name" value="Legumain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00776">
        <property type="entry name" value="HEMOGLOBNASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0788">Thiol protease</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035814353" description="Legumain prodomain domain-containing protein" evidence="9">
        <location>
            <begin position="23"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="Legumain prodomain" evidence="10">
        <location>
            <begin position="374"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR019663-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF20985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0554538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="54058" checksum="CB3C2A048821C3E5" modified="2022-10-12" version="1">MEFVQGLLRVLLLSLYVVNSLSRLHSPWDGKIAMKTEDEDKTEMGTRWAVLIAGSSDYGNYRHQADVCHAYQILKRGGLKDENIVVFMYDDIANNDENPYPGKIFNKPNGPDVYHGVPKDYTGSNVTVSNFYAAILGDKDAIKGGSGKVVASGPNDHIFIFYTDHGGAGVLGMPNDPILYADEFVDTLKKKAAAGTFKKMVIYLEACESGSIFDGLLPEGLNIYVTTASDPEENSWGTYCPGMDPPPPPEFGTCLGDLYSVAWMEDAEIENLKQETLKDQYIIVKSRTSDHDTYMTGSHVMQYGDIKIDAEEMELYLGFDPANENVTKPELPQAALVNAQGTHVPQREAELLHLWHKYHRAVEGSAKKEHAGIELTRTIAHRMHVDNSVKLIGDLLFGLDNSLKTLKAVRPAGQVLVDNWACLKSMVRTFEASCGPLTQYGMKHMRAFANICNAGVDINAMTRATSKACRINDIDGGIRTSDTSRFSPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GA56</accession>
    <name>A0A8T0GA56_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Galactose oxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_11G023900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GA56"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd02851">
        <property type="entry name" value="E_set_GO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.80">
        <property type="entry name" value="Galactose oxidase/kelch, beta-propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037293">
        <property type="entry name" value="Gal_Oxidase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009880">
        <property type="entry name" value="Glyoxal_oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015202">
        <property type="entry name" value="GO-like_E_set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208:SF98">
        <property type="entry name" value="GLYOXAL OXIDASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32208">
        <property type="entry name" value="SECRETED PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07250">
        <property type="entry name" value="Glyoxal_oxid_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09118">
        <property type="entry name" value="GO-like_E_set"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="E set domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="Galactose oxidase, central domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035937069" description="Galactose oxidase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Glyoxal oxidase N-terminal" evidence="3">
        <location>
            <begin position="51"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Galactose oxidase-like Early set" evidence="4">
        <location>
            <begin position="477"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0556073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="595" mass="65088" checksum="7BAB99F027A54992" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBA8</accession>
    <name>A0A8T0GBA8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">dynamin GTPase</fullName>
            <ecNumber evidence="1">3.6.5.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_11G018700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.5" evidence="1"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBA8"/>
    <dbReference type="OrthoDB" id="5562561at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1240:FF:000011">
        <property type="entry name" value="Dynamin-2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004149">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1240">
        <property type="entry name" value="Dynamin, middle domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019762">
        <property type="entry name" value="Dynamin_GTPase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000375">
        <property type="entry name" value="Dynamin_stalk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003130">
        <property type="entry name" value="GED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020850">
        <property type="entry name" value="GED_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF57">
        <property type="entry name" value="DYNAMIN-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01031">
        <property type="entry name" value="Dynamin_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02212">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00302">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00410">
        <property type="entry name" value="G_DYNAMIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51388">
        <property type="entry name" value="GED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0493">Microtubule</keyword>
    <keyword evidence="6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="11">
        <location>
            <begin position="44"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PH" evidence="9">
        <location>
            <begin position="574"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="GED" evidence="10">
        <location>
            <begin position="757"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="515"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="629"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="709"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="852"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="515"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="531"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="548"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="872"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="883"/>
            <end position="893"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="930"/>
            <end position="942"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0555995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="942" mass="101191" checksum="F2ED32194D932D91" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GD66</accession>
    <name>A0A8T0GD66_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G041300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GD66"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF288">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="5">
        <location>
            <begin position="144"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0556294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="442" mass="49282" checksum="A183E97A2BA55DD2" modified="2022-10-12" version="1">MAGLEHTTLVEVNFESTSDATKAVVEESTATMERLTLSTAKEESSCSGAGASLGCASLPSDPAHSSSEYFSARIQSIVESKSEFETALDAEIEASKGHWSELPPGSGAQGCAEADMELFRRLQEQYATPDGEHGFFSDWDEDECEVGEKIAEGGQGAIHELRWLRPEDAHGNGKLVVKVFKLEGWSLEALHQQWPPAMLHKILITSHDPEKRVYGGDGIAPVGKGVMLKDGRFGFVMGRFWGDLRTMIDRRMVHNGNQAPPFSIKGSLWILHDIAKGMLQLHTDGILHRDLKASNVLILPMMWKFEERGAYGKYDSINDDEFLVCIADYECSVAVCGTKFWRAPEILLGVKNRDLQPNSWTKKSDVYSYGMTCYEVLTGKIPLENLRPNDYNVVIEGLRPVIPNDISSSIQSLLARCWHQNPVERPSFEEILKELEKNNELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEW3</accession>
    <name>A0A8T0GEW3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G110900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035755965" description="Secreted protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="86" mass="9626" checksum="BBA225B72707DB37" modified="2022-10-12" version="1">MSIQQCGFFFFFPRLQTFVVAGGCKHCCISTSAAWGQTKGRLEGTEAERSLHLPDHRFGNVRPLFQSDLFGILCRSSLFFLSSSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFG9</accession>
    <name>A0A8T0GFG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SOUL heme-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G100000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HEBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.80.10:FF:000002">
        <property type="entry name" value="Heme-binding protein 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="entry name" value="Regulatory factor, effector binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006917">
        <property type="entry name" value="SOUL_heme-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220:SF1">
        <property type="entry name" value="HEME-BINDING PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11220">
        <property type="entry name" value="HEME-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04832">
        <property type="entry name" value="SOUL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="Probable bacterial effector-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035921583" description="SOUL heme-binding protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="219" mass="24023" checksum="A3CE86A7290C22D5" modified="2022-10-12" version="1">MGPKMSVWMVLAMAAVVCAAAGADSIESPPYTVVHAESDFEIRLYRPSTLITTPVEDISFSKATQIGFHKLFQYIQGANLNNSRVEMTTPLLTGIVPSAGPFCSSAFAIRFFVPHEFKDSPPLPLLDSDLTVENWDEKCVAVRAFSGFAKDTNVAQEAAQLEASLQNSKWANITDLEPKDGEDAYTIDQYSSPFKILGRVNEVWVSFPSSEGCFISILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GGZ8</accession>
    <name>A0A8T0GGZ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transferrin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G130300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GGZ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="CDD" id="cd13529">
        <property type="entry name" value="PBP2_transferrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001156">
        <property type="entry name" value="Transferrin-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11485">
        <property type="entry name" value="TRANSFERRIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11485:SF58">
        <property type="entry name" value="TRANSFERRIN-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00405">
        <property type="entry name" value="Transferrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00422">
        <property type="entry name" value="TRANSFERRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00094">
        <property type="entry name" value="TR_FER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51408">
        <property type="entry name" value="TRANSFERRIN_LIKE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035815102" description="Transferrin-like domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Transferrin-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="399" mass="41093" checksum="22A95208AD80AD47" modified="2022-10-12" version="1">MAGSKVAFGFVLVASLFVCSVWAQGPVAAPAAVTSWTWCVSDKADKPACDSMTAMLATIEQPALHKHSCVVGASHEDCMKKINAGEVQFGVFDGSFIDQAAATYNLRAIRTEGSSVGTDNQYYAVGIVKKSACPKSMADLKGKRSCHSGYGRSAGWTLPIATLVNSNIISTVSQTPQANDIESVTAFFAKTCAASNTPATAICSACKTTTGCTAADAYANYEGAFRGVVEGACDVAFTKFTIPAEYALGGPKAQSDWTGLEAPSAYALLCPGASNVCGDITSYATCNFGSAPAHTVMTSGTYPQAEINAFHVVMDKANSNAEFNDMFFAGKNVDGAIFSSDATKTLAYNGTATALTTSINNAKKTLNTLNDAATVSGAASIAKGGALAVASVLVSLLML</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GI15</accession>
    <name>A0A8T0GI15_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G127500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GI15"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="459"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="628"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="870" mass="96974" checksum="4A9F636E6F921211" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIE1</accession>
    <name>A0A8T0GIE1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_11G137800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIE1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0557528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="52" mass="5934" checksum="613464F0C8968A53" modified="2022-10-12" version="1">MVRMRSFGDACTKSIKTATGMRITKTQLMRILLLGGRSWIIKSANFRVLYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK64</accession>
    <name>A0A8T0GK64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G068200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="145" mass="16359" checksum="6FE12647BCA7A5AD" modified="2022-10-12" version="1">MVKLSQARKPGPSSEPFSKISSGSKVERHSTKLPVLSYLLPYASRNHGTLELFFLHTFWLHLPRRWSKSFDSLIVVRSGVFSALGKQKSSPRRASGTTGIKERDIETSIASLHGNLPEHRMINRHPDCCTKSCPWVVHVEIYVCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMQ0</accession>
    <name>A0A8T0GMQ0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G016000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMQ0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="108" mass="12290" checksum="FB91CBAAE32A78C1" modified="2022-10-12" version="1">MTSRRQGHACKHAKTSRETHQSSTTPLTPQKINPNHDAHHVKPEDNTPCTCHSTWQLRSRLPHSTTQKIHSTRERTQKNERITASVAHLERAPKQAPLPKRSPQSQTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQV0</accession>
    <name>A0A8T0GQV0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G109800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQV0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0562006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10184" checksum="90C7A003CAD900C9" modified="2022-10-12" version="1">MLIGVFNTVHCAMCLFCYVVLIFLIIFFAHSEPKDSIAMHGTKYNGTCYNPTGENRFIKLEPTEAQVTSFLYWPWINSNLTSIEVELTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRE5</accession>
    <name>A0A8T0GRE5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G073400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GRE5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="12209" checksum="136ECB39398E62E3" modified="2022-10-12" version="1">MKFSDFTFLSKEKRPPLFKLRTYCRSTVSENALMVSLRLRTRNEVLPVRKVNDEEFEMIRERLAKKLRFDFTETPNVSVNGGHGMKFPNVNSIQQKLCKRLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS00</accession>
    <name>A0A8T0GS00_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G146500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS00"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0562441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="14207" checksum="66C85F6A6F3432B8" modified="2022-10-12" version="1">MSEFKFTANLAFNAFRCSNIKEAFKRCHLFMKSSDDSPLSDPTWRLLHHDQSSELRRTRGQEDSSQKLRVRYKLGVSAVNAMCERIQSRLLYSEFVSYIRRLTLHLLRSLRLLTNCFAPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GSA4</accession>
    <name>A0A8T0GSA4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_9G048100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GSA4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0561239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="89" mass="10365" checksum="3631C6CB9FBA3172" modified="2022-10-12" version="1">MVMLPKPCLTLLAVSQFRWLWQDTRTSVSISVTRTELWSMNVWHRLRHIKNCPTMCLRRNGSSWIHFDGCPFLRPLLPHCGKEKPAGCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTB9</accession>
    <name>A0A8T0GTB9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G022200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="292" mass="33838" checksum="CE51B31059BEE7B2" modified="2022-10-12" version="1">MTMITFANVFAVLASIAGILANLVKIPVWINVTCLTILLFISLIPLVSSLITFLRLKTSRWMCLKLDIYSYILGSTFEGWLAQRMVEGKAICCNNNLKEPQTILFDEYFTFDSRSRHYFLKKTPVSLNYTCAFQYMCYHQPLAEPETDGFTTPGGTFSELERSEHDLDGVMKLVEIERVCIYFQTGEITQRISYDRDTQLCSVANFIYTHSKKHIVGQFVIKDLKRIKQLFYMKGIESDYPKLKVAKFVKMRRGVMVMHYSGDVAFYNQLRVKDIVRVKLDKCETLSYEGVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GU84</accession>
    <name>A0A8T0GU84_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Pectinesterase</fullName>
            <ecNumber evidence="5 12">3.1.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_9G149600</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>[(1-&gt;4)-alpha-D-galacturonosyl methyl ester](n) + n H2O = [(1-&gt;4)-alpha-D-galacturonosyl](n) + n methanol + n H(+)</text>
            <dbReference type="Rhea" id="RHEA:22380"/>
            <dbReference type="Rhea" id="RHEA-COMP:14570"/>
            <dbReference type="Rhea" id="RHEA-COMP:14573"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:140522"/>
            <dbReference type="ChEBI" id="CHEBI:140523"/>
            <dbReference type="EC" id="3.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell envelope</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the pectinesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.11" evidence="5 12"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GU84"/>
    <dbReference type="OrthoDB" id="2019149at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030599">
        <property type="term" value="F:pectinesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042545">
        <property type="term" value="P:cell wall modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045490">
        <property type="term" value="P:pectin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="2.160.20.10:FF:000008">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033131">
        <property type="entry name" value="Pectinesterase_Asp_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000070">
        <property type="entry name" value="Pectinesterase_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321">
        <property type="entry name" value="ACYL-COA THIOESTER HYDROLASE YBHC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31321:SF139">
        <property type="entry name" value="PECTINESTERASE CATALYTIC DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01095">
        <property type="entry name" value="Pectinesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00503">
        <property type="entry name" value="PECTINESTERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 12" id="KW-0063">Aspartyl esterase</keyword>
    <keyword evidence="8 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0964">Secreted</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Pectinesterase catalytic" evidence="13">
        <location>
            <begin position="106"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00047928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0562473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="393" mass="42971" checksum="C990C86BB607E210" modified="2022-10-12" version="1">MGATAMKTSKVWRPRAASSHLFVMFYITVLLLFSDLQLSHSTRSMSSKNSRLESEAMPSTMEDVESDFLSWIASVGAKSKSSSLAPITRLPSSVKAVPQVYYVDVAGFGNFKTVQEAVNAVPDGNSMQVLIIVKPGTYRERVTIPKSKGYITLQGAGKNVTFIEYDMNAATAGSTYDSATVAVFSDYFVAKDISFKNSAPAPPAGAVNMQAVALRITGDCAAFYNCGFYGSQDTLNDDMGRHYYKNCEIVGSIDFIFGDAQSLYKDCTLNVNAATYGSVTAQKRESSNKNTGFSFVGCNLLGSGQVYLGRAWGPYSRVVFAFTFMQDIVIREGWHNWNVPDRQRTAYYGQYKCSGPGATELGRVAWSHELTDAEAAPFLTLSFIDGQNWVTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV88</accession>
    <name>A0A8T0GV88_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G043900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV88"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050796">
        <property type="entry name" value="SCF_F-box_component"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672">
        <property type="entry name" value="BNACNNG10540D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31672:SF2">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="7"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="394" mass="45048" checksum="660E59E983774C72" modified="2022-10-12" version="1">MAMSEMESMWRDLPAEILENVFTFLPISSLCRFRTLSKRWNIYISSPAFRLAQASRLVSPEEYVVLVRFWGHEQRSGWNVLDKAKRKFLFLGDDFLRNHLLQRHPYQDAYLEAADGGLFCMRCDWQSDDITGPTCLFVCNPVLKTFKELPHLAAKAPHIVMSTDIVLMEYEIIAINSPTSPASVFVYESKIGSWRVVPYNQIYCRPEWRMWRTLTTFKNKQYWINSGSCEGHHTCEGIVCYDKDTRVVSDLAGLHMPFHDPTGRTRFTRHLVVSQDKLFGVMFVESLSDIFSSVSIFKINIAKEERIHMTEVPRELLVWVLGPNLEWGTIHLVVVTGSADSILISNVGRCAAYNLLDKSWYQCPDPLEGFHGAGPGISKNVSYSDSCCLSFCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXN0</accession>
    <name>A0A8T0GXN0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ferredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G082100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </cofactor>
        <text evidence="8">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Plastid</location>
            <location evidence="8">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the 2Fe2S plant-type ferredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXN0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010241">
        <property type="entry name" value="Fd_pln"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02008">
        <property type="entry name" value="fdx_plant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112">
        <property type="entry name" value="FERREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43112:SF3">
        <property type="entry name" value="FERREDOXIN-2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="2Fe-2S ferredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="8" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="5 8" id="KW-0249">Electron transport</keyword>
    <keyword evidence="6 8" id="KW-0408">Iron</keyword>
    <keyword evidence="7 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0934">Plastid</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="9">
        <location>
            <begin position="52"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="144" mass="15448" checksum="B48F5E9376CDE704" modified="2022-10-12" version="1">MAALTSSIAPVAVMAPTSWRGSTVRSSSESMAKAFGLEAGSAGRVTCMATTYKVTFKTPEKTYTIDVPEDENLLDTAEYAGYDLPYSCRVGACYSCASVLESGKVNQDEQTFLDDNQVAAGFVLTCVAYPRSDCTIRTHQEDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GY71</accession>
    <name>A0A8T0GY71_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G036900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GY71"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000427">
        <property type="term" value="C:plastid-encoded plastid RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042793">
        <property type="term" value="P:plastid transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038958">
        <property type="entry name" value="PTAC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37257">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37257:SF1">
        <property type="entry name" value="PROTEIN PLASTID TRANSCRIPTIONALLY ACTIVE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="160" mass="18049" checksum="A243EA38C08A9C78" modified="2022-10-12" version="1">MALSSAPSFCFCASVSNDVLAYASRSSTHLVQQQSKGLPRISCKADDTIGSKRKGRRGGRKDPLMDEKEGIWPYLQTQERMIVDLNKQLLVDTENLLHRANNKFGLVLEIAEEANEYLRNNKDEALTKKPILKVMSDRINEAAGENIRDAYCEETFDPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H088</accession>
    <name>A0A8T0H088_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 7">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_8G134800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 7"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H088"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.40.10:FF:000008">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000017">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000025">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050754">
        <property type="entry name" value="FKBP4/5/8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46512:SF9">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 7" id="KW-0697">Rotamase</keyword>
    <keyword evidence="4 8" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="57"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="173"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="10">
        <location>
            <begin position="293"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="8">
        <location>
            <begin position="484"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0564730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="575" mass="63666" checksum="7C4040475C469C4E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0H2</accession>
    <name>A0A8T0H0H2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G100200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0H2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9638" checksum="5C87EB28AD6A8D9F" modified="2022-10-12" version="1">MNHHKFVKGRQQPLLLNPQFASSQGSEWLRVNLVCSANRLQGENIVTKIKILQFSCNCVFRHRSHARYMLQLSIVLLPRLPAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1S9</accession>
    <name>A0A8T0H1S9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G135500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1S9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44575">
        <property type="entry name" value="OS01G0589200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44575:SF2">
        <property type="entry name" value="OS01G0589200 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="59"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="279" mass="31122" checksum="C61E4363218C83B0" modified="2022-10-12" version="1">MSSDVELGLSNVGTGVMAKETEELFVKQAEVYKEARPRAPEELYSYLASLTPSHELAWDVGTGNGQAAAVISKHYKKVIATDVASEQLKYAEKRPNITYSATPTTLSKDDLTRIVGPEGSVDLVLIVEALHWFDFDKFYENVKYVLRKPGGVIAATVYPSRPRVEGAQLTKALDDFWASIERHWSPQIFEYVETGYKNLPFPFAPVVQGNEVPHFEATVDARFGEFVNYLKSLSGVQTAIDRGEDPLNEDQMKVFADAWGPPETVRCLRWPLDMVVGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H366</accession>
    <name>A0A8T0H366_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G056800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000793">
        <property type="term" value="C:condensed chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000796">
        <property type="term" value="C:condensin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007076">
        <property type="term" value="P:mitotic chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941:SF4">
        <property type="entry name" value="AH_BAR DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43941">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="285"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="483"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2121"/>
            <end position="2156"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="615"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="780"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1397"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1560"/>
            <end position="1682"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1717"/>
            <end position="1790"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1991"/>
            <end position="2018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="46"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="95"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="149"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="285"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="483"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="2126"/>
            <end position="2140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2156" mass="245569" checksum="80F0036A48A792E5" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H421</accession>
    <name>A0A8T0H421_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G196400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H421"/>
    <dbReference type="OrthoDB" id="3340520at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="323" mass="36497" checksum="8E88A85801BA3B68" modified="2022-10-12" version="1">MAVAEMEMLGRGSALAQLFALLCDIASTFCSSLVRSLFLAIRLLFQWTMNVRLGEGGARRAGEVEFYEGKVWHERRKPVVHRFEYNVRYALVNLDMAPSWFDASHHMRACEARAIAATSGPVHLLTMPTSMGYEQNPLSVYYCYDEQGGVSQCIAEVTNTPWAERVTFLFAPGLDQVAKPLHVSPFMDMKAVWQMQAATPGQELLLRIGAQHPDLGNYFLAILKAKRVERAVDPEAFTWIMPHKVAFWIYWQALQIMLKGVSFIPHPKYIDGDGYRERAQQHVTHTCPTLLKMDGASVAKDVDGSSTSQRFCTWSEAPGYPWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5A9</accession>
    <name>A0A8T0H5A9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_7G064000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. ADCK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5A9"/>
    <dbReference type="OrthoDB" id="427480at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05121">
        <property type="entry name" value="ABC1_ADCK3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050154">
        <property type="entry name" value="UbiB_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566">
        <property type="entry name" value="CHAPERONE-ACTIVITY OF BC1 COMPLEX CABC1 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10566:SF119">
        <property type="entry name" value="OS04G0640500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="218"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="695"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0566440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="932" mass="102943" checksum="652185152B5B22B1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5S4</accession>
    <name>A0A8T0H5S4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G039000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5S4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37028:SF4">
        <property type="entry name" value="ALMS MOTIF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37028">
        <property type="entry name" value="UNNAMED PRODUCT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="937"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="217"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="970"/>
            <end position="983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="990" mass="111922" checksum="BAFC32761CAC46A7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H733</accession>
    <name>A0A8T0H733_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G075800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H733"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004159">
        <property type="entry name" value="Put_SAM_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108:SF1144">
        <property type="entry name" value="METHYLTRANSFERASE PMT10-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03141">
        <property type="entry name" value="Methyltransf_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 6" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035852052" description="Methyltransferase" evidence="7">
        <location>
            <begin position="32"/>
            <end position="644"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="644" mass="72666" checksum="E4700DEF75EF9D5D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H7Y3</accession>
    <name>A0A8T0H7Y3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G066500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H7Y3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="433"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="434"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0566474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="494" mass="55020" checksum="42167025E0DB657C" modified="2022-10-12" version="1">MVASPKSQVLVAYKRPPRAHFFTTAIPLHLEGTPTPVMALTVKFSQRQHSLHHPSPSGDAHYASHGWLCASQISAPNQISGKHSEISNMGQLCNVGVGVRPSQASGLPGNEDQSHSGGRCGGWRPQQLEEMATEISQVAPKETLIMEPVPVNSSDMDVRVLTKSMSKTQLRQRIPFAADEEVTRSVTGDHSQYNHGGIESSQLDVHNDKASGKSKFWGHGFHYRKISNATDDGVGSHGFLPGLMKKAGFGSQEFKEKDIQASEHTSGMPRSRSHGFLPGLIKRAGFGSQEFKEFLCHSAKNLTEIHPHHQPHSHHHGTRDKEIFGFEDAGVHDRDHENLFGIRDMEYQENVERADTMFGFEDTEFERGQKGRDLFGSDDPDTLSFRRGLEILGPLEADAEEIDKTRHVFGDENAEDSDDDEYLQDYAAATLEPAHQHSSDAEDDRAHEKAVHHENKVEVGVKLMNNLGELFSKKWVVKKGSRRSTSPKRQEYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9L2</accession>
    <name>A0A8T0H9L2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Beta-hexosaminidase</fullName>
            <ecNumber evidence="7">3.2.1.52</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_7G094100</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.</text>
            <dbReference type="EC" id="3.2.1.52"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.52" evidence="7"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9L2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004563">
        <property type="term" value="F:beta-N-acetylhexosaminidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030203">
        <property type="term" value="P:glycosaminoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06562">
        <property type="entry name" value="GH20_HexA_HexB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.80:FF:000063">
        <property type="entry name" value="Beta-hexosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.379.10">
        <property type="entry name" value="Chitobiase/beta-hexosaminidase domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025705">
        <property type="entry name" value="Beta_hexosaminidase_sua/sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015883">
        <property type="entry name" value="Glyco_hydro_20_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029018">
        <property type="entry name" value="Hex-like_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029019">
        <property type="entry name" value="HEX_eukaryotic_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600">
        <property type="entry name" value="BETA-HEXOSAMINIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22600:SF21">
        <property type="entry name" value="BETA-HEXOSAMINIDASE A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00728">
        <property type="entry name" value="Glyco_hydro_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14845">
        <property type="entry name" value="Glycohydro_20b2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001093">
        <property type="entry name" value="B-hxosamndse_ab_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00738">
        <property type="entry name" value="GLHYDRLASE20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55545">
        <property type="entry name" value="beta-N-acetylhexosaminidase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035824730" description="Beta-hexosaminidase" evidence="9">
        <location>
            <begin position="27"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-hexosaminidase eukaryotic type N-terminal" evidence="11">
        <location>
            <begin position="80"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoside hydrolase family 20 catalytic" evidence="10">
        <location>
            <begin position="222"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001093-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0566869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="581" mass="65950" checksum="E19618016DC6419D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBL4</accession>
    <name>A0A8T0HBL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Glycylpeptide N-tetradecanoyltransferase</fullName>
            <ecNumber evidence="2 5">2.3.1.97</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G184100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>N-terminal glycyl-[protein] + tetradecanoyl-CoA = N-tetradecanoylglycyl-[protein] + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15521"/>
            <dbReference type="Rhea" id="RHEA-COMP:12666"/>
            <dbReference type="Rhea" id="RHEA-COMP:12667"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57385"/>
            <dbReference type="ChEBI" id="CHEBI:64723"/>
            <dbReference type="ChEBI" id="CHEBI:133050"/>
            <dbReference type="EC" id="2.3.1.97"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.97" evidence="2 5"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBL4"/>
    <dbReference type="OrthoDB" id="60315at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004379">
        <property type="term" value="F:glycylpeptide N-tetradecanoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.170:FF:000002">
        <property type="entry name" value="Glycylpeptide N-tetradecanoyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000903">
        <property type="entry name" value="NMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022677">
        <property type="entry name" value="NMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022678">
        <property type="entry name" value="NMT_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022676">
        <property type="entry name" value="NMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377:SF5">
        <property type="entry name" value="GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11377">
        <property type="entry name" value="N-MYRISTOYL TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01233">
        <property type="entry name" value="NMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02799">
        <property type="entry name" value="NMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015892">
        <property type="entry name" value="N-myristl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00975">
        <property type="entry name" value="NMT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00976">
        <property type="entry name" value="NMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase N-terminal" evidence="8">
        <location>
            <begin position="75"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="Glycylpeptide N-tetradecanoyltransferase C-terminal" evidence="9">
        <location>
            <begin position="248"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0568067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="438" mass="49709" checksum="A0E557CFA0710060" modified="2022-10-12" version="1">MVGSGNKSDNGATAPSPSEDQAPKDGSLMAMGHPSSVDSVTRKLQKGATLENEKRHLFWETQPVGKYQDGVGEGPIEPSQPLSEVRQEPYNLPSTYEWCTCDLTDEQTMREVYTLLTNNYVEDDDNMFRFDYSVAFLRWALNPPGYFPSWHIGVRAKSSKKLVAFITGIPAKIRAHETVVPMAEINFLCVHKKLRSKRLAPVLIKEVTRRVHLEDMWQAAYTAGVVLPTPISTCQYWHRPLNPKKLIDVGFSRLAPRMTMSRTIKLYRLPDEAATPGFRPMERRDVAAVTRLLQTYLAQFQVAPHFSEDDVEYLLLPIDNVINSFVVENSESHEITDFASFYTLPSTIIGNQNYSLLKAAYSYYNVATSTPLLQLMSDVLVMAKQRDYDVFNALDVMQNESFLKELKFGPGDGQLHYYLYNYRLRAPLKPAEMGLVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE34</accession>
    <name>A0A8T0HE34_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-2-amino-thiazoline-4-carboxylic acid hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G073100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE34"/>
    <dbReference type="OrthoDB" id="5034840at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026002">
        <property type="entry name" value="ATC_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14196">
        <property type="entry name" value="ATC_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="237" mass="27148" checksum="E6B8200845ED05DC" modified="2022-10-12" version="1">MRWRERVWRWVNQSAEVYFDGLPRKAFINSLTNCLREYPQLNGRESLIVHRIEELCHSGMERHAAMAVDNRGSTHLQIACLVQGTYQTLLPWFKNDQEKVMEIIRKPVGESSAAAVGVAQRIALLLSFDKFRLVSKGLRHMEADFGKAFVVEHHEKPGFHRARVSRCLYHSVFTAEGNPELTPIFCALDSMWFDQLKPQKHGVEFQRPTTLARGNSACDFVLRRIPGRSVTQGQAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE72</accession>
    <name>A0A8T0HE72_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G139000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE72"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd11733">
        <property type="entry name" value="ASKHA_NBD_HSP70_HSPA9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.34.10:FF:000014">
        <property type="entry name" value="Chaperone protein DnaK HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000020">
        <property type="entry name" value="Chaperone protein HscA homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.30.30:FF:000003">
        <property type="entry name" value="Heat shock protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.10:FF:000001">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000004">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.640.10:FF:000003">
        <property type="entry name" value="Molecular chaperone DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.10">
        <property type="entry name" value="Actin, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="entry name" value="Substrate Binding Domain Of DNAk, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001413">
        <property type="entry name" value="PRK00290.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003520">
        <property type="entry name" value="PRK05183.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="HEAT SHOCK PROTEIN 70KDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00301">
        <property type="entry name" value="HEATSHOCK70"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="Actin-like ATPase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="Heat shock protein 70kD (HSP70), peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="647"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0570106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="681" mass="72853" checksum="CDDAACA2453592C6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HFB9</accession>
    <name>A0A8T0HFB9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_6G165000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
            <orientation evidence="2">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the complex I NDUFA1 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HFB9"/>
    <dbReference type="OrthoDB" id="1920692at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017384">
        <property type="entry name" value="NADH_Ub_cplx-1_asu_su-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098:SF2">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17098">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE MWFE SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15879">
        <property type="entry name" value="MWFE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="8" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0570471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="65" mass="7550" checksum="902E4B405EED6680" modified="2022-10-12" version="1">MSWEAMLPMGIISAMIFVMGTSQFVIHTSIYGKPKHPRHDAWDRAMDARDERLKEEYEKSQVSAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGR7</accession>
    <name>A0A8T0HGR7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Guanine nucleotide-binding protein subunit beta-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G080400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGR7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF9">
        <property type="entry name" value="GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035791399" description="Guanine nucleotide-binding protein subunit beta-like protein" evidence="5">
        <location>
            <begin position="30"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="351"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="514"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="694" mass="76111" checksum="557A5E4E486F249D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGZ1</accession>
    <name>A0A8T0HGZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G128800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="84" mass="9510" checksum="A3B6A97D4B3D7F90" modified="2022-10-12" version="1">MDKAIKVQAAAISEVVYCRFPLSFHLLALSWSMSKEASFELYGGAEFGASDLECAHSRIFDQLQGRLVRLVRCLILIRKKFLDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHL5</accession>
    <name>A0A8T0HHL5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cyclin-dependent kinases regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_6G183200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the CKS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHL5"/>
    <dbReference type="OrthoDB" id="440676at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.170.10:FF:000003">
        <property type="entry name" value="Cyclin-dependent kinases regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.170.10">
        <property type="entry name" value="Cyclin-dependent kinase, regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000789">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036858">
        <property type="entry name" value="Cyclin-dep_kinase_reg-sub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23415">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01111">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00296">
        <property type="entry name" value="CYCLINKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01084">
        <property type="entry name" value="CKS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55637">
        <property type="entry name" value="Cell cycle regulatory proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00944">
        <property type="entry name" value="CKS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU311113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0570725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="91" mass="10656" checksum="868E9107A16B37A3" modified="2022-10-12" version="1">MPQIQYSEKYFDDTYEYRHVVLPPDIAKLLPKNRLLSEAEWRGIGVQQSRGWVHYAIHRPEPHIMLFRRPLNYGQPQQAAAVQQQPAGMKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHU4</accession>
    <name>A0A8T0HHU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G047000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="212" mass="23852" checksum="A8FC1F76E3F58000" modified="2022-10-12" version="1">MQSVVLLQSTAWSATIGLSYMDQSHDIPGGAAHSFDIKGYHFDSVPNVVIFRALVSRCASQPLSPAFRIYSKSLNQMQGRMAQAPGRNNTFLNFRPVTCFDIWFFCFKNFHFQYILVSCSWPCTVLYMSCLSEKQFFRDRQQPSCRDMYRMPEAPGTSLEPCGQSLLQAFFIFGPQGVYPSGEFARHSLELVDSLEICNALAQNCCSSSSPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HIG8</accession>
    <name>A0A8T0HIG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G162100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:004208">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19241">
        <property type="entry name" value="ATP-BINDING CASSETTE TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="837"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="879"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="916"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="946"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1041"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1466"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1550"/>
            <end position="1572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1578"/>
            <end position="1601"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1608"/>
            <end position="1628"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1718"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="334"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="10">
        <location>
            <begin position="1118"/>
            <end position="1359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="114"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="25"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="51"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="78"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="115"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="157"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0570439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1748" mass="194470" checksum="248D33EC3B833CB4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKY7</accession>
    <name>A0A8T0HKY7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_VG011500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKY7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0571444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="133" mass="15384" checksum="DF34393FE731CF72" modified="2022-10-12" version="1">MVDESTLVVTIHRGPASEERLQTMPPPKVKEDRHHFIKTLRACHVRPLKSTRQDIPTAYHRMVGSHSFDGPWYTLSGPVVSELVKSARYYSKKQTFCHFTRRWVDFVALNHVKTGDTVVFSEVDKSEFEVKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HL53</accession>
    <name>A0A8T0HL53_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG020900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HL53"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12623" checksum="6E4FAC42B70523E1" modified="2022-10-12" version="1">MERTSQREDSRSALFELKKAWEWSDWNLCRRRRGRGDRGGHGKPSQGVDIQSLRNPVHLQRCSCSTSYPATPISVFTTISSSLYTSLPLSLVFIPLPLGVFRVGDEDTCKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HLU4</accession>
    <name>A0A8T0HLU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG041200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HLU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="14098" checksum="7D7A48B26DAC31DF" modified="2022-10-12" version="1">MALDILTQSLRGRHAVLGVMPMRHSVSLWEAWDLSTNALRIFEPPRTSFLLSHSQCLQSRRCSLSKCTYNSIRCCCLPLNPNVLLVQLVTMRYVCYEMEMGFDLGLDVRFIKLKHRVGSFGFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMM4</accession>
    <name>A0A8T0HMM4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG066000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009448">
        <property type="term" value="P:gamma-aminobutyric acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000014">
        <property type="entry name" value="Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, probable"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049704">
        <property type="entry name" value="Aminotrans_3_PPA_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004767">
        <property type="entry name" value="PRK06105.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42684:SF3">
        <property type="entry name" value="ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0572076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="489" mass="54013" checksum="B95E417A03F0E990" modified="2022-10-12" version="1">MTPGISAPVVAGPNESDAIDSQKNASHAALDAVHHERTFQGHSMLAPFTSGCQQTEVEPLIIEKGEGIYVWDHNGKKYLDALAGLWCTSLGFSEERLMNAAWNQMTKLPFYHSFWNRTSQRPLDLAKELIDMFKPVKMGKVFFCCTGSEANDTQVKLVWYYNNALGREKKKKIIARQKSYHGSTLSAASLSGLTPLHTGFDLPASFVLHTDCAHYWRYHLPNESEEQYSSRLADNLEKLILKEGPETIAAFIAEPLMGAGGVIPPPATYWDKIQPILKKYDILLIADEVICAFGRLGTMFACEKYNIKPDLVTIAKQLSSGYMPISAILLGQHIFDALASYSNGLGTFGHGFTYGGHPVACAVALETLRIYKERSILVHINEVAPIFQTEMKKLASSPIVGEIRGEGLVLGIEFVGDKKIKKSFPAEWGVGAYFSGQCTVLGMLIRFAGDMAMMSPPLIITIEEIHEILRISAAALKATEEHVLELQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMM9</accession>
    <name>A0A8T0HMM9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_VG064700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMM9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000293">
        <property type="term" value="F:ferric-chelate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06186">
        <property type="entry name" value="NOX_Duox_like_FAD_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013121">
        <property type="entry name" value="Fe_red_NAD-bd_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050369">
        <property type="entry name" value="RBOH/FRE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972:SF69">
        <property type="entry name" value="FERRIC REDUCTION OXIDASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11972">
        <property type="entry name" value="NADPH OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08030">
        <property type="entry name" value="NAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00052">
        <property type="entry name" value="Ferric_Reductase_Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01168">
        <property type="entry name" value="Ferric_reductase_subgroup_(FRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="338"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="619"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="377"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0572045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="801" mass="89714" checksum="D95DC6B71167F792" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN39</accession>
    <name>A0A8T0HN39_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_VG078200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN39"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="Beta-glucanase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044791">
        <property type="entry name" value="Beta-glucanase/XTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008263">
        <property type="entry name" value="GH16_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31062">
        <property type="entry name" value="XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01034">
        <property type="entry name" value="GH16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="29"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0572227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="373" mass="42606" checksum="FACEF721C2D99735" modified="2022-10-12" version="1">MESLILFRRSAFRELFFKLLFLALACNYAPFPAIVVDAHYLRRIDHRLDRTRERLDDNGLWHYGCADPFKCKMGPGPAPATAPSTFEPPSFEGDMVPWYIHYMNVSNNYESMAASPDGLHVNLSITNDHIVSGRMYSKSMFLFGYFSMKMKLVPNESAGVISTFYLISSDFDTRDEIDFEFLGNTTGNPITLQTNVYMDGAGFRAQQHYLPFDPAANFHKYSVLWNQHLIIWFVDDKVIRVFHNKSNEIATHYPMSKPMQVQATIWTELNPTNDWATQGGRVHIDFAYAPFVAQYEGFGGVDGCPVCAATPPTACENLSVCSDASKYWFQQQEYLTEEQVNQLKDHRQNHVISDYCRRSEGAPEECPYNSFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HN83</accession>
    <name>A0A8T0HN83_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_VG079700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Mitochondrion inner membrane</location>
            <topology evidence="1 11">Single-pass membrane protein</topology>
            <orientation evidence="1 11">Matrix side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the complex I NDUFA13 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HN83"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045271">
        <property type="term" value="C:respiratory chain complex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009346">
        <property type="entry name" value="GRIM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966:SF0">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12966">
        <property type="entry name" value="NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06212">
        <property type="entry name" value="GRIM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6 11" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU368034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0572261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="15503" checksum="33CD368C1A37E6B9" modified="2022-10-12" version="1">MTETTIRGQKGMTSVKEMPVLQDGPPPSGFPAVRYARRIVNSGPSGATVLLVSSVIIGWGMYQVGQGNIFRRGLKAEKLAARQAIVPFLQAEEDARFVREKNKLLEEEAKVMAHVPGWKVGENVYNSGRWMAPSSGKLGMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HP11</accession>
    <name>A0A8T0HP11_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG103600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HP11"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="46" mass="5578" checksum="6F042D32B6ACABD4" modified="2022-10-12" version="1">MGTKKNRHARHAVSTRRELRLMGSERREIEIQETRKEERLQVYRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ64</accession>
    <name>A0A8T0HQ64_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="29">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G002700</name>
        <name evidence="5" type="ORF">KC19_10G021800</name>
        <name evidence="6" type="ORF">KC19_10G119300</name>
        <name evidence="3" type="ORF">KC19_11G025800</name>
        <name evidence="1" type="ORF">KC19_12G062100</name>
        <name evidence="2" type="ORF">KC19_12G138300</name>
        <name evidence="44" type="ORF">KC19_1G010700</name>
        <name evidence="45" type="ORF">KC19_1G047900</name>
        <name evidence="46" type="ORF">KC19_1G108100</name>
        <name evidence="47" type="ORF">KC19_1G159600</name>
        <name evidence="48" type="ORF">KC19_1G266200</name>
        <name evidence="41" type="ORF">KC19_2G005200</name>
        <name evidence="42" type="ORF">KC19_2G178300</name>
        <name evidence="43" type="ORF">KC19_2G199800</name>
        <name evidence="39" type="ORF">KC19_4G098000</name>
        <name evidence="40" type="ORF">KC19_4G098800</name>
        <name evidence="35" type="ORF">KC19_5G034900</name>
        <name evidence="36" type="ORF">KC19_5G155500</name>
        <name evidence="37" type="ORF">KC19_5G160000</name>
        <name evidence="38" type="ORF">KC19_5G174900</name>
        <name evidence="21" type="ORF">KC19_6G022600</name>
        <name evidence="22" type="ORF">KC19_6G045300</name>
        <name evidence="23" type="ORF">KC19_6G187300</name>
        <name evidence="17" type="ORF">KC19_7G000500</name>
        <name evidence="18" type="ORF">KC19_7G009700</name>
        <name evidence="19" type="ORF">KC19_7G115400</name>
        <name evidence="20" type="ORF">KC19_7G153300</name>
        <name evidence="15" type="ORF">KC19_8G013200</name>
        <name evidence="16" type="ORF">KC19_8G158100</name>
        <name evidence="7" type="ORF">KC19_9G002800</name>
        <name evidence="8" type="ORF">KC19_9G063300</name>
        <name evidence="9" type="ORF">KC19_9G070600</name>
        <name evidence="10" type="ORF">KC19_9G108100</name>
        <name evidence="11" type="ORF">KC19_9G108700</name>
        <name evidence="12" type="ORF">KC19_9G119300</name>
        <name evidence="13" type="ORF">KC19_9G135600</name>
        <name evidence="14" type="ORF">KC19_9G164800</name>
        <name evidence="24" type="ORF">KC19_VG003000</name>
        <name evidence="25" type="ORF">KC19_VG005200</name>
        <name evidence="26" type="ORF">KC19_VG014900</name>
        <name evidence="27" type="ORF">KC19_VG022500</name>
        <name evidence="28" type="ORF">KC19_VG063300</name>
        <name evidence="29" type="ORF">KC19_VG139200</name>
        <name evidence="30" type="ORF">KC19_VG156400</name>
        <name evidence="31" type="ORF">KC19_VG213400</name>
        <name evidence="32" type="ORF">KC19_VG217900</name>
        <name evidence="33" type="ORF">KC19_VG220800</name>
        <name evidence="34" type="ORF">KC19_VG224400</name>
    </gene>
    <organism evidence="29 49">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="29 49" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="29 49">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="29">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ64"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="49" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0558076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0558352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0560659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0561419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0561989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0562113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0562305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0562689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0563222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0565034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0565596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0565718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0567156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KAG0567673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0568486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0568786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG0570778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0571337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="EMBL" id="KAG0571360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="26">
        <source>
            <dbReference type="EMBL" id="KAG0571482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="27">
        <source>
            <dbReference type="EMBL" id="KAG0571564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="KAG0572029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="EMBL" id="KAG0572986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="KAG0573191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="EMBL" id="KAG0573834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="32">
        <source>
            <dbReference type="EMBL" id="KAG0573880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="33">
        <source>
            <dbReference type="EMBL" id="KAG0573911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="34">
        <source>
            <dbReference type="EMBL" id="KAG0573951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="35">
        <source>
            <dbReference type="EMBL" id="KAG0575847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="36">
        <source>
            <dbReference type="EMBL" id="KAG0577433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="37">
        <source>
            <dbReference type="EMBL" id="KAG0577487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="38">
        <source>
            <dbReference type="EMBL" id="KAG0577704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="39">
        <source>
            <dbReference type="EMBL" id="KAG0579426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="40">
        <source>
            <dbReference type="EMBL" id="KAG0579439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="41">
        <source>
            <dbReference type="EMBL" id="KAG0585357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="42">
        <source>
            <dbReference type="EMBL" id="KAG0587618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="43">
        <source>
            <dbReference type="EMBL" id="KAG0587903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="44">
        <source>
            <dbReference type="EMBL" id="KAG0589295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="45">
        <source>
            <dbReference type="EMBL" id="KAG0589786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="46">
        <source>
            <dbReference type="EMBL" id="KAG0590546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="47">
        <source>
            <dbReference type="EMBL" id="KAG0591222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="48">
        <source>
            <dbReference type="EMBL" id="KAG0592604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="49">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19415" checksum="6CDCDB1F0742FEB8" modified="2022-10-12" version="1">MLFLHFHVGLWSKMPLGELKPLLTHILPAGVMERLSFVYSRSDLIDRENFPWSYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRRTPNCMCYIPWPFQGHLNFPNDDGVIPNIATDILPLVYPLHKFGSVPEYMAQACRPGQVHWAIEAARKFGRARVDWTEVCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HT24</accession>
    <name>A0A8T0HT24_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG198900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HT24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035734768" evidence="1">
        <location>
            <begin position="20"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="100" mass="11848" checksum="62EE3CFBB47123B6" modified="2022-10-12" version="1">MLGHLIIIRALLWAHAPSSQRPGQTDHSRLAQYVRSNPLQWTQPEIQHTINTYNYLGQGLQEFDRCEIELHIPEYDRRWRIRIHTTMNISRIKQSEASCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUT9</accession>
    <name>A0A8T0HUT9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG288000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUT9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6603" checksum="522223AEA6E3C7DC" modified="2022-10-12" version="1">MDLLTDPLHPLSSLPPTLPSSCGIRQALMRLHLATTELGRFNLRPKTSKGNMSPMSRNSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWB8</accession>
    <name>A0A8T0HWB8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG310600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWB8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="161" mass="18772" checksum="7434480163293386" modified="2022-10-12" version="1">MCCHWSRDDLTIKCDFTLYPDLQVSEAPFQEEVRPMGETGHSGTRRRKRYSSCVLRNDESSANASPVLSGSDVDSELSAEGSLYNSMKRIYQKYCEEAEAKSDMKLVKLTWDEYFTQQSIDDDEFNPEDTLESILSEIEDSPWPKEIKESMFRQMAHRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HX10</accession>
    <name>A0A8T0HX10_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G018100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HX10"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035888597" evidence="2">
        <location>
            <begin position="32"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0575624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="157" mass="16774" checksum="4179184DA33862AE" modified="2022-10-12" version="1">MLAPRTAAAPAPRLHAPAQLLLLLRPALIHCLPAFPKPLSSDHTRAPETSNPPRKNATNRRTIKPATQRECSARQVSRSATPIKARSRKTSSGKSATVSKSPNDASEAFLCLTAYPVPSCSAWAVVTRLYVLLGCGLVGRKVLFSRGAGHGCGERVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYW1</accession>
    <name>A0A8T0HYW1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Glutathione reductase</fullName>
            <shortName evidence="13">GRase</shortName>
            <ecNumber evidence="13">1.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_5G074600</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the reduction of glutathione disulfide (GSSG) to reduced glutathione (GSH).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 13">
            <text>2 glutathione + NADP(+) = glutathione disulfide + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11740"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58297"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="10">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.7" evidence="13"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.50.50.60:FF:000051">
        <property type="entry name" value="Glutathione reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006324">
        <property type="entry name" value="GSHR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01424">
        <property type="entry name" value="gluta_reduc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF2">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4 10 12" id="KW-0274">FAD</keyword>
    <keyword evidence="3 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 13" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 12" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="15">
        <location>
            <begin position="25"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="14">
        <location>
            <begin position="372"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="209"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="11">
        <location>
            <begin position="72"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU365040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0576370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="500" mass="53632" checksum="BCC7790BEDB68592" modified="2022-10-12" version="1">MPRTFPQPQQEDLHDNGEGPADYDYDLFVIGAGSGGVRASRTAAGFGARVGICELPYSPISSESTGGIGGTCVLRGCVPKKILVYGSAFSGEFQDAREFGWNINGDITFDWKRLIANKTNEITRLNGVYRKLLTGSKVDMYEGGGKIVDPHTVEVQETDGKSKRFTTKRILVATGGRAVLLNIPGKELAITSDEGLSLEEFPKRVVIAGGGYIAVEFAGIYSGMGAKVDLFYRKPYPLTGFDEEMRAVVASNLEGRGIHCHPETNLKKLEKVAGGIKVTTDKDEVFEADAVMFATGRKPSTKNIGLESVGVELDQVGAIKVDEYSRTNVPSIWAIGDVTNRINLTPVALMEGTCFAKTEFAGTPMKPNYENVASAVFCQPPLSVVGLTEDQAVKEAKGDILVFSSSFNPMKNTISGRKEKTVMKLIVDADTDKVLGAAMVGPDAAEIIQGVAIALKCGATKAQFDATVRITLHNKDASLCRSSGLTLYPLCSTEIVAFII</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0H5</accession>
    <name>A0A8T0I0H5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">ATP synthase subunit b', chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_5G077700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0H5"/>
    <dbReference type="OrthoDB" id="3819at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045259">
        <property type="term" value="C:proton-transporting ATP synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015986">
        <property type="term" value="P:proton motive force-driven ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06503">
        <property type="entry name" value="ATP-synt_Fo_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01399">
        <property type="entry name" value="ATP_synth_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034679">
        <property type="entry name" value="ATP_synth_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050059">
        <property type="entry name" value="ATP_synthase_B_chain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33445">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT B', CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33445:SF2">
        <property type="entry name" value="ATP SYNTHASE SUBUNIT B', CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0138">CF(0)</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="196"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0576405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="252" mass="27655" checksum="627A04E18679D816" modified="2022-10-12" version="1">MAAMAAMTSSAAVVASLPAGLRSTGLSASRQVVSLGVRRSAVERVARKAMEVRAGMAPLSELEGSVKQAIRSVKDAASQSALMKQASFLAFNALMVLPALAEEIEKEPKGKIFDFNLTLPIIAVQFLLLMVALDNIWFKPVAKVMDARDENIRKKLMGVRDNSGEIKKMQEEAEAILRAARIETTDALSKTKKETAAMLDEKLQESRNRIEKELAQSLANLEEQKEDTLRSLDKQVQTLSEEILSKVIPFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0T9</accession>
    <name>A0A8T0I0T9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G089100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0T9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11388" checksum="E3ACCD01E8F7C99E" modified="2022-10-12" version="1">MILSVQEQPFMKPNTTDSRANLTFPSITEFQNAFILHDFHNFTLAFENDLEIIPVHKVEKYRLISNLMIITHSDAIEPSSFLELSDSDHLPHSVCTNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I1D5</accession>
    <name>A0A8T0I1D5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G083600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I1D5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043367">
        <property type="entry name" value="PLIP1/2/3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46483:SF4">
        <property type="entry name" value="PHOSPHOLIPASE A1 PLIP2, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="510"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="415"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="112"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="854"/>
            <end position="863"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0576483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="863" mass="95910" checksum="17123C9BCEAE2A97" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7Y0</accession>
    <name>A0A8T0I7Y0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G110700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7Y0"/>
    <dbReference type="OrthoDB" id="508902at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35691">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35691:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="105" mass="11501" checksum="3C04F560509BC28A" modified="2022-10-12" version="1">MAISPPAQEHNLDECSLYGSWIFSLLGAAIAIPVGIRKKSLAPLVFFGSTGAMLDIVQSFADCERERVEKERAAELLVQRDPADLSDELAFKDDAASSLRFSEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9R7</accession>
    <name>A0A8T0I9R7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G118400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9R7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="14960" checksum="10BDEFEA824A317D" modified="2022-10-12" version="1">MPKKTPASPPTQTDLLHITCSGPGLRSMRRLCPKSRHENANSLNIPRVCADVGEREMEMTQLSGRWPRLSHGHDHGWQPTLANWGGGNESREDARWRGMSTLLTQPAKAASQHFVAAISTATSAACPGTQYLNQTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAS7</accession>
    <name>A0A8T0IAS7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G141500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAS7"/>
    <dbReference type="OrthoDB" id="75724at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008526">
        <property type="term" value="F:phosphatidylinositol transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.525.10:FF:000008">
        <property type="entry name" value="Phosphatidylinositol transfer protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011074">
        <property type="entry name" value="CRAL/TRIO_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052578">
        <property type="entry name" value="PI_Transfer_CRAL-TRIO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824:SF6">
        <property type="entry name" value="F16L1.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45824">
        <property type="entry name" value="GH16843P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03765">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00180">
        <property type="entry name" value="CRETINALDHBP"/>
    </dbReference>
    <dbReference type="SMART" id="SM01100">
        <property type="entry name" value="CRAL_TRIO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="2">
        <location>
            <begin position="88"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0580006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="324" mass="36872" checksum="FB2B91365016E87C" modified="2022-10-12" version="1">MTSFLKKSASKVGSRNLDEPSTPEDEQTKVSELRAAIGPLTGRLDQFADDACLKRYLRARNWNVKKSEKMLKDSLAWRETYKPEEIRWSDIAGESETGKVYRANFKDKSGHTVLVMHPGRQNTTNADLQMKQLVYFLENAILNLPEDQEQMIWLIDFKGWSMKKSSPVSVARETANILQNHYPERLHVAILYNPPRLFEAFWMIVKPFLDPKTFRKVKFVYAKNAESQKIMTELFEEDAIKRTFEDPNDYSHEDYAKLMQDDDVKSTLHWKGVGETKPEHDEAQNGSDVPNMEGLKIEDTPANGHTDAPAAPAVAAAPVVAPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBG3</accession>
    <name>A0A8T0IBG3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G165700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBG3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="48" mass="5645" checksum="D3F13F2A5D81F698" modified="2022-10-12" version="1">MQWIESEVLTHKEKQQCPASGCLNFLDAFYYIVVTNMPLYIGGYGWIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ID24</accession>
    <name>A0A8T0ID24_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pentatricopeptide repeat-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G202000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PPR family. P subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ID24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447">
        <property type="entry name" value="OS03G0856100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47447:SF17">
        <property type="entry name" value="OS12G0638900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="268"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="303"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="3">
        <location>
            <begin position="339"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="69"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="393"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="69"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="99"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="399"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1106"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1120"/>
            <end position="1133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0580817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1133" mass="129062" checksum="F7D11DA201205841" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE07</accession>
    <name>A0A8T0IE07_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G193100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE07"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="122" mass="13569" checksum="6928665A77188902" modified="2022-10-12" version="1">MKTPTWSNRVSGLCILSSYAKPTVPITRIQHLKQSTNPIRNLKHPNNNPMSLTLKNSKPTHSQFPQISSVSFQLRLNQTYQSPIALTTCSIVNHSHHSQNLSTSIPLPESQLPLPSSSNTLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG53</accession>
    <name>A0A8T0IG53_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G016800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG53"/>
    <dbReference type="OrthoDB" id="336088at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10539">
        <property type="entry name" value="SET_ATXR5_6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053114">
        <property type="entry name" value="ATXR5/ATXR6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442:SF1">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="289"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="48035" checksum="F24BADE81518AC06" modified="2022-10-12" version="1">MEDEECGRGKRVKRVIVCRNGWHNCCLPEFEKTGPCGMHFKVSPSQTRVKVVDAGSVTESTQLVVKAKEPKSKEVVEVQERALEFAKPRKRAASKAKDAKPKKDKYDTTLCEECSRGDGEQEMLLCDSCDRGYHMYCLSPILPTVPLGEWFCPKCAESSLVQEFPKVQKKIVDFFRIQKPAPFTTETKCIETRKRRRPSGGTLCRQKKSRRLLPYVPCTDPQRRLEQMASLATALTSIGVEFTDSLSYGLAPRSANRAENEKGGMQVMGKEDRATLDLCKTMCSQGEWPPLMVTHDSRQGFVVEADRNIKDMTIIAEYTGEVDYMCRRQYDSGNSIMGLLFTEDPAKELVICPDRRGNIARFVSGINNHTSEGRKKQNVRCVRYNIDGEARAILVAIRDIPKGERLYYDYNAYQTEYPTEHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0II64</accession>
    <name>A0A8T0II64_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G100300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sterol desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0II64"/>
    <dbReference type="OrthoDB" id="408954at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050307">
        <property type="entry name" value="Sterol_Desaturase_Related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11863">
        <property type="entry name" value="STEROL DESATURASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035934910" description="Fatty acid hydroxylase domain-containing protein" evidence="7">
        <location>
            <begin position="23"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="8">
        <location>
            <begin position="185"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0582992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="37517" checksum="F947DB8F5C030268" modified="2022-10-12" version="1">MATSGVVMRGAVCMVALVAVWGVVCMGADVEVVNGSSYATSGAVPGENVVPLVKGSPEYLQLFVEETRWYNDIVLGWWLPRSVRDAIPHTLQTWLRNYLAGLLLYFSSGGLWCLYIYSWKGEHFFPAGGIPAKEPIMLQIWVTMKAMPVYTGLPTLSEYMIEKGWTKSFARIEDVGLPTYVCLVLTYLFVVEFGIYWMHRELHDIKPLYKYLHATHHIYNKQNTLSPFAGLAFHPIDGCLQACPHVIALFLMPMHFFTHEILLFCEGVWTTNIHDCIDGNVWGIMGAGYHTIHHTTYRHNYGNYTVLFDWLFGTLRDPVERKLETHAKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IK68</accession>
    <name>A0A8T0IK68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GOLD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_3G120100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the EMP24/GP25L family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IK68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015720">
        <property type="entry name" value="Emp24-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009038">
        <property type="entry name" value="GOLD_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22811">
        <property type="entry name" value="TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01105">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01190">
        <property type="entry name" value="EMP24_GP25L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50866">
        <property type="entry name" value="GOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="GOLD" evidence="9">
        <location>
            <begin position="89"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0583237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="288" mass="32675" checksum="4FFA39FF3715C12E" modified="2022-10-12" version="1">MDERACDFGRTAPDYTRIVSLNGRGLVGTSTKCKIEIWNRGSFKIFREVEMAAAAKRSNSREYWRWIVTVLAVVSLGGTQGIKFNVHEHECWVHETEVENELVQMFVEVLIDVNPGPFRHMGVDVVIQAPGGQYIHTEKVKQEAIPDVKTYDADANTKMAKYEATINFTAVEKGRYNICFHNRGNVVETVRLEMLHELGSDHDEPVKDVHIRSLMDQMASLSDALVDVEFEQDRLASHRDRHASILSDLSKRVVYKAVLEAFAFIACSVIQVVLLQRLLHKHLAGKQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMK4</accession>
    <name>A0A8T0IMK4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G163100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMK4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0583788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7110" checksum="246A084B49D37BEB" modified="2022-10-12" version="1">MIVKPLLSHSSELSLGYTQLCPFGEGCIHLIRLSCKHPKILFRNSRGKHVMNFANLLTRMNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IMU4</accession>
    <name>A0A8T0IMU4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Nodulin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G256400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IMU4"/>
    <dbReference type="OrthoDB" id="410267at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd17354">
        <property type="entry name" value="MFS_Mch1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056555">
        <property type="entry name" value="NFD4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010658">
        <property type="entry name" value="Nodulin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576:SF167">
        <property type="entry name" value="OS09G0536700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21576">
        <property type="entry name" value="UNCHARACTERIZED NODULIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23262">
        <property type="entry name" value="NFD4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06813">
        <property type="entry name" value="Nodulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="355"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="382"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="448"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="Nodulin-like" evidence="7">
        <location>
            <begin position="12"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="NFD4 C-terminal" evidence="8">
        <location>
            <begin position="349"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="274"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF23262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0585080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="602" mass="65989" checksum="C97838B69335C1C9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPF2</accession>
    <name>A0A8T0IPF2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hexosyltransferase</fullName>
            <ecNumber evidence="4">2.4.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_3G230000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 4">Glycan metabolism; pectin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Golgi apparatus membrane</location>
            <topology evidence="4">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glycosyltransferase 8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.-" evidence="4"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPF2"/>
    <dbReference type="OrthoDB" id="411524at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047262">
        <property type="term" value="F:polygalacturonate 4-alpha-galacturonosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06429">
        <property type="entry name" value="GT8_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029993">
        <property type="entry name" value="GAUT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002495">
        <property type="entry name" value="Glyco_trans_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32116:SF27">
        <property type="entry name" value="GALACTURONOSYLTRANSFERASE 13-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32116">
        <property type="entry name" value="GALACTURONOSYLTRANSFERASE 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01501">
        <property type="entry name" value="Glyco_transf_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0584716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="530" mass="60416" checksum="25FB8F6F68088187" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQP1</accession>
    <name>A0A8T0IQP1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_2G060800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQP1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002812">
        <property type="entry name" value="DHQS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056179">
        <property type="entry name" value="DHQS_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563:SF1">
        <property type="entry name" value="3-DEHYDROQUINATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01959">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26558">
        <property type="entry name" value="DHQS_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dehydroquinate synthase N-terminal" evidence="4">
        <location>
            <begin position="427"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="3-dehydroquinate synthase C-terminal" evidence="5">
        <location>
            <begin position="718"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="332"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="371"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="639"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="376"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="406"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="640"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="695"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF26558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0586064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="887" mass="96356" checksum="3E35D7699B41954B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRJ7</accession>
    <name>A0A8T0IRJ7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_2G010700</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Deltex family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="4"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRJ7"/>
    <dbReference type="OrthoDB" id="9984778at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007219">
        <property type="term" value="P:Notch signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09633">
        <property type="entry name" value="Deltex_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.50">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039396">
        <property type="entry name" value="Deltex_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039399">
        <property type="entry name" value="Deltex_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039398">
        <property type="entry name" value="Deltex_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018123">
        <property type="entry name" value="WWE-dom_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004170">
        <property type="entry name" value="WWE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037197">
        <property type="entry name" value="WWE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12622">
        <property type="entry name" value="DELTEX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18102">
        <property type="entry name" value="DTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02825">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00678">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117839">
        <property type="entry name" value="WWE domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50918">
        <property type="entry name" value="WWE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0914">Notch signaling pathway</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="WWE" evidence="13">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="12">
        <location>
            <begin position="229"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0585421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="45784" checksum="E19D0E5749D9FD59" modified="2022-10-12" version="1">MAIVWEWMTDALLWKPYSPALSTAIEASFSAHQPSVDVCIASPSAPVPTHTITFQSQSPCQTTWGSGRSRPVRRNVDPQTGTVEWQWWEDVSQQWHPYDVSINFQIESAWGQCHSSANAYFQASAPGGVSIRIHHRKFTIEFEADAVQKNVFSHFSRKVRRRVVPPGTGAGASAAAMVGPAALPSAPHASLSQQAVSVPPPSVAAGTVSLSYDANDLQPFVETSDDNDCPICVTSLRERNSVMLAKCRHVFCKECIMRWFETRPTCPVCTMAYGVITGIQPNGTMSVRIIPTDSPEFGSGLEGFPGVDIIQIHYNFPSGIQGPEHPSPGRRYTGTRRVAYLPFTKEGEDVLSLLKTAWDRRLLFSVGTSITTGQRDVVTWSGVHHKTNTWGGPTNFGYPDATYFARVKAELAEKGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRM5</accession>
    <name>A0A8T0IRM5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDSL esterase/lipase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G030300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 'GDSL' lipolytic enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRM5"/>
    <dbReference type="OrthoDB" id="1600564at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01837">
        <property type="entry name" value="SGNH_plant_lipase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="entry name" value="SGNH hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001087">
        <property type="entry name" value="GDSL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051058">
        <property type="entry name" value="GDSL_Est/Lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035669">
        <property type="entry name" value="SGNH_plant_lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648">
        <property type="entry name" value="GDSL LIPASE/ACYLHYDROLASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_4G14700)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45648:SF166">
        <property type="entry name" value="OS02G0617400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00657">
        <property type="entry name" value="Lipase_GDSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035948695" description="GDSL esterase/lipase" evidence="3">
        <location>
            <begin position="27"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0585695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39771" checksum="A3BDE64E761B0E52" modified="2022-10-12" version="1">MTTMEGKLVLLLSVLMVVTMSPVVNAQGKKAPATFVFGDSLVDVGNNNYFFTLASADHKPYGIDRADKVATGRFCNGKIIPDLVNDYLGTPYPLPVLAPEATGGNLLHGVNYASAGAGIQEETGQVFIGRVTMSQQFDHFTKTKQQIALMVGQQGMEELIHNGIYSFTVGGNDYINNYMALTTNTKNMYTLPQYLDRLITLFRGQLKTAYGLGMRKFIISNMGPIGCAPSVLSTRSKNGECVQEVNDYAINFNNALKPMLESVQTELPGSVILYANAFGVVKSIIDNPLKYGFTEPVTTACCGVGKFNGIDGACRTIGNLCADRTKSVFWDAFHPTETVNRMSFQVFLNGGPDVISPMNVKQLLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISP9</accession>
    <name>A0A8T0ISP9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G113600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="92"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="350" mass="40274" checksum="D770BC19B788EC55" modified="2022-10-12" version="1">MVTPQESQISRYDQLKESVRVLRQQVRGSCRGASRKSQKSLHNGCSALVTPASAPHEGDETGYCIPCDGSMTPRDGFDVIDPEESFSMQHLRLQFKIELQEKREEIKKLIANQRGKSQQIENLENEHKVQRRKLEARIEHQSEKICALEAQLSNRITLHQQELQAQAYAFAAQLRKCENEKCQQLVAVRMEHAATLASTEDHHRAELSQAQVIYVLSLKRAEDAEAKAKALEAEVVALKQRFTDTQELIMKKDEECSMKMDRMKAVYEDQVQDLRSRLKKEKVELERVKEDLTKQHTLELQSYKMQKAREIDQVSERVRAAVKIKDASIAQLKEELAKQQEQASFLLDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITI6</accession>
    <name>A0A8T0ITI6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G093100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd01763">
        <property type="entry name" value="Ubl_SUMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022617">
        <property type="entry name" value="Rad60/SUMO-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47813">
        <property type="entry name" value="UBIQUITIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47813:SF2">
        <property type="entry name" value="UBIQUITIN-LIKE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11976">
        <property type="entry name" value="Rad60-SLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="2">
        <location>
            <begin position="187"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="261" mass="29888" checksum="BF962E507D95E3A0" modified="2022-10-12" version="1">MAVFWYSLCACDVDEQLDDDDEDEFKPLFDYSDTVPRSPELLSSDDSDEDTVIIKSALPKRKFEISPPKEPLTPTLQRDETQKTILDDDEDDDSWLMTSPCKLPKLPSSAYFAENPILQQIRLQRQELMMLQQKASPEAIRRVEELARMQAQQRPEPVTPLVVKAPTRMNAHEESSGSESPAAEEKEKILLKVQNSTQSTQSIRIFTTDKFEKLFRVYADLTKLSLESMAFRFDGDQISPNSSPKELDMEEGDIIEVYIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUF9</accession>
    <name>A0A8T0IUF9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G091900</name>
        <name evidence="2" type="ORF">KC19_2G116300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUF9"/>
    <dbReference type="OrthoDB" id="26681at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0586777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="90" mass="9922" checksum="C45BCEEA7D3E606F" modified="2022-10-12" version="1">MINTSRDYNKGEDFEGINIGESAHSLFGVLPAMVETARRMRIIEVNRRSIAAAADEFGTTVGGRVWRSLIRRLQEMGALFGAITNQIGPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IUW3</accession>
    <name>A0A8T0IUW3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G114900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IUW3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8553" checksum="8B00E1F03F83F7E1" modified="2022-10-12" version="1">MTKVVSLFVYLGFKFSYFLVHTFSSHNPGTYYCFRSHQKKSICEKEDFYTYQYHSAGRIKQSDILLCQSMES</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IV29</accession>
    <name>A0A8T0IV29_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">H(+)-exporting diphosphatase</fullName>
            <ecNumber evidence="2">7.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G099300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IV29"/>
    <dbReference type="OrthoDB" id="5210at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:diphosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001953">
        <property type="entry name" value="PRK00733.2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001960">
        <property type="entry name" value="PRK00733.3-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="K(+)-INSENSITIVE PYROPHOSPHATE-ENERGIZED PROTON PUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="424"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="472"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="512"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="619"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="690"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="720"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0586551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="808" mass="85678" checksum="75229E2D275908A7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXT5</accession>
    <name>A0A8T0IXT5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G252200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXT5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="28"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1201" mass="137089" checksum="D53C81EE1CE4C6D1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IY45</accession>
    <name>A0A8T0IY45_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G181700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IY45"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="10915" checksum="67B50879EBE8C514" modified="2022-10-12" version="1">MIESTPAVTVGNTSSLDMSWCSKLTKLPDPIGGLRKLKTLNLIASLIESLPKVRWKSELVGKFEYVQVGEFHRCGTVGKLGNLKFCLSGFKSLPEFVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZH1</accession>
    <name>A0A8T0IZH1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein ABIL1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_2G292600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZH1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028457">
        <property type="entry name" value="ABI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10460:SF0">
        <property type="entry name" value="ABELSON INTERACTING PROTEIN, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10460">
        <property type="entry name" value="ABL INTERACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="195"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="290"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="19"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="208"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="248"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="304"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="388" mass="42162" checksum="A743C8A6D03A70F7" modified="2022-10-12" version="1">MAAATAPPNASPRLPIHASHPLSPSRSTSPSPSPSVDDDHDPAHMTFDELEMQRSRHFVQALKELKNLRPQLYSAAEYCESSYLYSDQKQVVLDNLKDYSVKALVNAVDHLGTVAYKLNDLLGQQTTEISATELRAASVAQRMRSCQEHSDREGLKQQSLAKTMHANHKHYVLPDPCAEGELNPSLVRENFDTVLSRQSPLKSESHPHSSPQMQPQPLAKDSSSADFASSSGSKSLAWHFTSEPAPTSTSEGSNSSSKRSISAGRRTPPPTASGRKVLETSLSKGSFLTPSLYNGDSMPRTSEAGLSTSKYPASAKLSTQRSGSFTPAKTAPPMRVGLVPGLLLGCPLCLLATFLLLQNTHSILLLLWKPFYFVIPTHSLCNLSVDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1R8</accession>
    <name>A0A8T0J1R8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">WD40 repeat-containing protein SMU1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G258700</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus speckle</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the WD repeat SMU1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1R8"/>
    <dbReference type="OrthoDB" id="674604at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016607">
        <property type="term" value="C:nuclear speck"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006595">
        <property type="entry name" value="CTLH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045184">
        <property type="entry name" value="SMU1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054080">
        <property type="entry name" value="TPR1-like_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21889">
        <property type="entry name" value="TPR1-like_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50897">
        <property type="entry name" value="CTLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="CTLH" evidence="10">
        <location>
            <begin position="105"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="284"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="335"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="380"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="422"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="464"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="8">
        <location>
            <begin position="520"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="601" mass="67253" checksum="1FEBD2FB18871EB3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J353</accession>
    <name>A0A8T0J353_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Proteasome subunit beta</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G061000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Non-catalytic component of the proteasome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J353"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051603">
        <property type="term" value="P:proteolysis involved in protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03760">
        <property type="entry name" value="proteasome_beta_type_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.20.10:FF:000014">
        <property type="entry name" value="Proteasome subunit beta type-7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="entry name" value="Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016295">
        <property type="entry name" value="Proteasome_beta4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194">
        <property type="entry name" value="METALLOPROTEASE TLDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32194:SF6">
        <property type="entry name" value="PROTEASOME SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001213">
        <property type="entry name" value="Psome_endopept_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="N-terminal nucleophile aminohydrolases (Ntn hydrolases)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="2 4" id="KW-0647">Proteasome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0589977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="267" mass="29838" checksum="494B77895D6E75D4" modified="2022-10-12" version="1">MRWESYNGGHEASEEEKQVYVGRSLMASSRPFTLMPTPGGPITHTQHPYVTGTSVLGLKYKDGVLIAADTAGSYGSTTRYKSVERLKQISNNTVLGATGEISDFQALTQLLDRLIVTDAMWDDGNNLGPLDIHNFLTRVMYNRRNKFDPLWNSLILGGVKNGVKYLGSVSMIGVHFVDQHIATGFGIHLAQPIFRSEWKENMTLEEGRKLLEKALLVLFYRDRSAINKIQIANITEDGVRISQPYALKPTWNFKAFKNPSSATPGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3P4</accession>
    <name>A0A8T0J3P4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PRONE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G107600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3P4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.2010:FF:000001">
        <property type="entry name" value="Rop guanine nucleotide exchange factor 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.2010:FF:000003">
        <property type="entry name" value="Rop guanine nucleotide exchange factor 14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2010">
        <property type="entry name" value="PRONE domain, subdomain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005512">
        <property type="entry name" value="PRONE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038937">
        <property type="entry name" value="RopGEF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33101">
        <property type="entry name" value="ROP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33101:SF6">
        <property type="entry name" value="ROP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03759">
        <property type="entry name" value="PRONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51334">
        <property type="entry name" value="PRONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0344">Guanine-nucleotide releasing factor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRONE" evidence="4">
        <location>
            <begin position="128"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="604"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="60"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0590540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="628" mass="70464" checksum="D6EED6271DB5096D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J578</accession>
    <name>A0A8T0J578_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Prenylcysteine lyase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G080500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prenylcysteine oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J578"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001735">
        <property type="term" value="F:prenylcysteine oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030327">
        <property type="term" value="P:prenylated protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030328">
        <property type="term" value="P:prenylcysteine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010795">
        <property type="entry name" value="Prenylcys_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017046">
        <property type="entry name" value="Prenylcysteine_Oxase1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944">
        <property type="entry name" value="FARNESYLCYSTEINE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15944:SF0">
        <property type="entry name" value="PRENYLCYSTEINE LYASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13450">
        <property type="entry name" value="NAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07156">
        <property type="entry name" value="Prenylcys_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035902038" description="Prenylcysteine lyase domain-containing protein" evidence="8">
        <location>
            <begin position="24"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Prenylcysteine lyase" evidence="9">
        <location>
            <begin position="131"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="465" mass="51337" checksum="9357C78A7379C875" modified="2022-10-12" version="1">MEKLCGLLVFLLMLAVGCAPCHGQNEICIVGSGMGGASVAYFLREYAREPLQISIFEERDRVGGRMSVVELEGDTFEAGASIIHPKNLHAVRFVELLGLNRTSDDGEKTFGIWDGTQFVLQTARAGDSIFSKTITRIMNTVTILWRYGTSLWRMQNYTNDRRAFKSVEGLLKSVDLYNNTQYTREELLPQAGLSRLFIDELVTVTMRINYGQNVSISGLAGGVSLAGAQGGVWAVAGGNWQLADGLIRHANASLSLNHKVLSITTVEDRYLLGSEGGTTTCDAVVLATPMDESNIIFTPSINIVKQHMQHTYTTFVRGLLNPDYFGSTSESILDLIGTKEDSKIPFSSISVHKEYNATDKAYKLFSGAPSSDELLGHIFRTYRSTIRIDWAAYPHYTAPERFSPYVLDGRNLYYINTFESAASAIETAAVSAQNVARLILSRHPEWGLQTPTPKDVSEQDVVEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5F8</accession>
    <name>A0A8T0J5F8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G151600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5F8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0591124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="137" mass="15395" checksum="8B453C135DD017EB" modified="2022-10-12" version="1" fragment="single">LFSVPLFLLSSGKAKPSSPATSESRELQQLPFRNENLRRRTVTKAKPGGNENRILSSTNNGFSDGSLDCVSFGICRHALRLFGSFCMTGRLQWRMRPAPSSSLHLCIVRIWALEFRSSRILSISGFCFFGFLGFWEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J655</accession>
    <name>A0A8T0J655_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G117200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J655"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0590656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="99" mass="11089" checksum="4528E7AA04469F33" modified="2022-10-12" version="1">MCFVREWCVGFFANAMHPWLSHMMVVASTWTHPTSPKSLRSQMASLVLWLVAMYSASVVDKAIVGCLLQFHEMAPSPTKKIYPVVERRSFASPAQSASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6R8</accession>
    <name>A0A8T0J6R8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histidine decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G160600</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6R8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051151">
        <property type="entry name" value="Group_II_Decarboxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46101">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46101:SF2">
        <property type="entry name" value="SERINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0591235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="546" mass="61046" checksum="8E25B86E4730A236" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6U4</accession>
    <name>A0A8T0J6U4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flowering time control protein FCA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G119600</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6U4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12633">
        <property type="entry name" value="RRM1_FCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000374">
        <property type="entry name" value="Flowering time control protein FCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000332">
        <property type="entry name" value="flowering time control protein FCA isoform X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002343">
        <property type="entry name" value="Hud_Sxl_RNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047193">
        <property type="entry name" value="RRM1_FCA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24012">
        <property type="entry name" value="RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00961">
        <property type="entry name" value="HUDSXLRNA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0217">Developmental protein</keyword>
    <keyword evidence="5" id="KW-0287">Flowering</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="114"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="205"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="WW" evidence="10">
        <location>
            <begin position="575"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="11">
        <location>
            <begin position="671"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="284"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="409"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="79"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="305"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="352"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="412"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00071861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0590689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="797" mass="86672" checksum="C6FCBAECD8579875" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J6U5</accession>
    <name>A0A8T0J6U5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G108700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J6U5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035885527" description="Secreted protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="12002" checksum="2CE3D5EADF2D586C" modified="2022-10-12" version="1">MYSGILIATLLMQLTRVNTKSITTSNPTWIPPLFEYYPQQHHYSPAKARTQPTVLPQPQIPSTTSQSIDQTNESGLQLARRMLWEIATRTQTRDHSMSQVCARPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J847</accession>
    <name>A0A8T0J847_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G193900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J847"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734">
        <property type="entry name" value="LYSM DOMAIN-CONTAINING GPI-ANCHORED PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33734:SF22">
        <property type="entry name" value="MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="111"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="157"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="24625" checksum="1B1F9E6570F32127" modified="2022-10-12" version="1">MALNSLVGSPVVGGASLLLSGCDSAQLRRHTPSSSVSYPKQRSCRTVVRSSRLPLNPREAREMSEGREPEKRNEGGGGGPNPFRFFQNFKDGLFADHKRLQKEKNLPKGHLMYTVEKGDTLYAISDRHDCSLELLMEANAIDDPHNLQVGQQIWIPRTYQIKKGDTLYSISKHYGVSIEDIQKANGIDDPNFIHEGDHICLPGDDDEKDSTASVNDLMMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J888</accession>
    <name>A0A8T0J888_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="6 10">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_1G226800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 10">
            <text>6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6 10">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6 10">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="6 10"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J888"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1040.10:FF:000002">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.320:FF:000001">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000007">
        <property type="entry name" value="6-phosphogluconate dehydrogenase, decarboxylating"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.320">
        <property type="entry name" value="6-Phosphogluconate Dehydrogenase, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="entry name" value="N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006765">
        <property type="entry name" value="PRK09287.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="6-PHOSPHOGLUCONATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="6-phosphogluconate dehydrogenase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="6 10" id="KW-0521">NADP</keyword>
    <keyword evidence="3 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6 10" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphogluconate dehydrogenase C-terminal" evidence="11">
        <location>
            <begin position="184"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="13"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="36"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="80"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <begin position="134"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <begin position="191"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" description="in other chain" evidence="8">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0592120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="504" mass="55621" checksum="48FF70596201A7B8" modified="2022-10-12" version="1">MASEGLSRIGLAGLAVMGQNLALNIAEKGFPISVYNRSASKVDETVERAKEEGNLPVRGFHDPCEFVKSIQKPRCIIILVKAGAPVDQTIELLSKYLEKGDCIIDGGNEWYENTERRAETVKAKGLLYLGMGVSGGEEGARHGPSMMPGGTLEAYKYIEEVVTKVAAQVNDGPCVTYVGPGGAGNFVKMVHNGIEYGDMELIAEAYDVLKSVGGLTNKELHETFYEWNKGELESFLVEITADIFSVPDDKGEGELVDKVLDKTGMKGTGKWTVQQAAELSIAAPTIATSLDLRYLSGLKEEREEASKVFKSLGVSEILTEVKVDKQELIDNVRKALYASKICSYAQGMNLIRAKSIEKGWNLNLGELARIWKGGCIIRAKFLDRIKQAYDRNPKLASLLIDPEFAKEMVERQGAWRKVVSLAIEVGVSTPGMSTSLAYFDTYRRARLPANLVQAQRDYFGSHTYERVDMKDSFHTEWYKIAKKLLGDRAATTGELHIGSKEQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8G5</accession>
    <name>A0A8T0J8G5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G144700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8G5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="115" mass="13637" checksum="37A77AF7FD5A2A61" modified="2022-10-12" version="1">MAAARCLIILDSGNIESEACCWGRLEQQCLSINQHYFFKTKLRCYWSDWFLQSSFFIWLSTFECVQAIFYLGGFSQTIEIILYCRSARVGIFITFFFPFFFSFFFFSLRVIISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9S1</accession>
    <name>A0A8T0J9S1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G195200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9S1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008390">
        <property type="entry name" value="AWPM-19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33294:SF5">
        <property type="entry name" value="AWPM-19-LIKE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05512">
        <property type="entry name" value="AWPM-19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="211" mass="22103" checksum="E7ACC190539DEEEB" modified="2022-10-12" version="1">MAGAGLGRGLATPLLVINFCLYLIAAILAGWALNRNFDAPLGRGEGAVGNVVTQSFFLPITLIACMVGLASVLAGVHHMRLFRSDSLAAAAAASLIAWLLVLLAMGLACKQIHTGGNRPRRLKVVEAFMIILALFELLYLLSLHAGFGRMGSGTGAGTGAGIGMGGHGHHHGARDPNIPVHNHEHHVDYGHHTDMKIPVGHVPHPAHPTTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCA8</accession>
    <name>A0A8T0JCA8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G337600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCA8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035852324" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="37" mass="3827" checksum="96C3C6DF6D366842" modified="2022-10-12" version="1">MASALLLQPHAVAVLGAGVGCSYQDSWVLTRRGGSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDU4</accession>
    <name>A0A8T0JDU4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G309600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JDU4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="14869" checksum="481B36E976C520C1" modified="2022-10-12" version="1">MSYIFQSGDVLLMKPTSTLADSQLPHVRPVQLGVPAEIGSEIAIKQPGDARSTVLTEISSMPSMIEFCCVVVAGTCRDRIRSAAGLVRIGSHVFRSRSIFNSRKILEVIWIPGNGLPQFVLSLEISFEIQCMCMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JF09</accession>
    <name>A0A8T0JF09_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G333100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JF09"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0593479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="150" mass="17004" checksum="C5CE1C581413FC28" modified="2022-10-12" version="1">MGHSFRDSLQERPLAPCLAHAVAMLSPCAKGLTLHKHQGLLTSSLGGRKTSSFHPTHSIKPGNFLHSSKEHYHIYGQLLWPTFLHTQAHLGSLSCDVEYSSLLANRSASFEVLFNYSFDVFNYAIEYLFYVFARLRCRKGSTPQSRVYIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G369</accession>
    <name>A0A8T0G369_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G004800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G369"/>
    <dbReference type="OrthoDB" id="441812at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016279">
        <property type="term" value="F:protein-lysine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd10527">
        <property type="entry name" value="SET_LSMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1410.10">
        <property type="entry name" value="set domain protein methyltransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050600">
        <property type="entry name" value="SETD3_SETD6_MTase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271:SF91">
        <property type="entry name" value="PROTEIN SET DOMAIN GROUP 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13271">
        <property type="entry name" value="UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="39"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="501" mass="55981" checksum="2DE2D21D5742D7D9" modified="2022-10-12" version="1">MAVEDAEQYADLLGWAASKGITDTPPELEWAGDSPTLGFSLRIATFPEAGGRGLTAARELKLGELILRVPEEALMNGKSARQDVELARVLASCPSLSDVQVLCVHLLREIAKGRTSERYPYLVHLPRYYHTASFYSSFEAQALQVKDAVSMAEGAAQSCREQWLEARPVLGKLELGRRFSTFQAWLWASATIASRTLYVPWDEAGTLCPFGDFFNYACPGVSYDSPTSTQDTSVEDGDSYGLEIRDRLRDGGFEHDRAEYCFYARQDYQEGQQVLLCYGTYTNLELLEHYGFLLPFNPNDKIHIDLPSVDELNPGASRGCQEAVSPKDLYIDHEGKPSFSLLSNLRLRAAPASLLKTRRHLALAGQQISPESDKVLFQWLKTKCQTILRSCSTSLQADELLLKIIDAHPAMVQIQKFLAVCKDDTASPSIRSDLLFNASEHLHAVITHEVEGFIASVSHSDASSTSSLQEDLRLERWRLAVEWRLGFKKVVMRCISRCSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4D3</accession>
    <name>A0A8T0G4D3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G001000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4D3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035834467" description="SH3 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="107" mass="11394" checksum="73A329B1D5F6E62C" modified="2022-10-12" version="1">MGEKASVLLVVVLVLSCFACTSCITGTILNRTLLQLGPGAGQTVLTTLLPSDIVDVSCRTQDALVYDDPWWLKVTYTPPNGSTTTGWVADYYVDCGNVGNCNVTQCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G628</accession>
    <name>A0A8T0G628_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Transcriptional adapter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_12G087000</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G628"/>
    <dbReference type="OrthoDB" id="270417at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00167">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02335">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.60.90:FF:000013">
        <property type="entry name" value="Transcriptional adapter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.10:FF:000087">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000115">
        <property type="entry name" value="Transcriptional adapter 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041983">
        <property type="entry name" value="ADA2-like_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016827">
        <property type="entry name" value="Ada2/TADA2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017884">
        <property type="entry name" value="SANT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007526">
        <property type="entry name" value="SWIRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055141">
        <property type="entry name" value="TADA2A_B-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000433">
        <property type="entry name" value="Znf_ZZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043145">
        <property type="entry name" value="Znf_ZZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374:SF20">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTER 2-ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12374">
        <property type="entry name" value="TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22941">
        <property type="entry name" value="TADA2A-like_3rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25299">
        <property type="entry name" value="ZZ_ADA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF025024">
        <property type="entry name" value="Transcriptional_adaptor_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00717">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00291">
        <property type="entry name" value="ZnF_ZZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50090">
        <property type="entry name" value="MYB_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51293">
        <property type="entry name" value="SANT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50934">
        <property type="entry name" value="SWIRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01357">
        <property type="entry name" value="ZF_ZZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50135">
        <property type="entry name" value="ZF_ZZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 9" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZZ-type" evidence="13">
        <location>
            <begin position="46"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="HTH myb-type" evidence="16">
        <location>
            <begin position="101"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="SANT" evidence="15">
        <location>
            <begin position="104"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Myb-like" evidence="12">
        <location>
            <begin position="109"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="SWIRM" evidence="14">
        <location>
            <begin position="531"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="204"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="283"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="487"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="242"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR025024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG0554381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="627" mass="69424" checksum="6281ABCB9FD8CDD1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G778</accession>
    <name>A0A8T0G778_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G046900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G778"/>
    <dbReference type="OrthoDB" id="1913299at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04301">
        <property type="entry name" value="NAT_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="330" mass="35482" checksum="5ADCF47261CA797D" modified="2022-10-12" version="1">MAASSDRNGSADMSGGFEVTKVGGVRIRPLRPDDAMALAQSCFDSFTAFNNSVNIPPHLDFPSVEFTHGVIKHLATVPGMYAVVAEEESSGDLMGAGFMTSGDAYGIGPVWADNAYKGKGAGKAVMIALIAKAKSENAKSIRLNQISANVVSFSLYASLGFLPVECWQELVGCVTEEKSLSASRSVGLQPLTGVHVRKMEDADVKVCNELHVKANGLGRTEEIETAIPAGNSWVLVRNEEIIAYTLGFDLMGHTVAQTEEALVSLFTGVCLQHPDSSPHPTLHLPSKLYPRLLHWALAAKLKVSRSCWLMVIGFYQSPQHDMVYCPGVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8M5</accession>
    <name>A0A8T0G8M5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Eukaryotic translation initiation factor 3 subunit E</fullName>
            <shortName evidence="4">eIF3e</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Eukaryotic translation initiation factor 3 subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G076500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the eIF-3 subunit E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8M5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016282">
        <property type="term" value="C:eukaryotic 43S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033290">
        <property type="term" value="C:eukaryotic 48S preinitiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071540">
        <property type="term" value="C:eukaryotic translation initiation factor 3 complex, eIF3e"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001732">
        <property type="term" value="P:formation of cytoplasmic translation initiation complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21378">
        <property type="entry name" value="eIF3E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03004">
        <property type="entry name" value="eIF3e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016650">
        <property type="entry name" value="eIF3e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019010">
        <property type="entry name" value="eIF3e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000717">
        <property type="entry name" value="PCI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10317">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09440">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21357">
        <property type="entry name" value="EIF3E_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01399">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016255">
        <property type="entry name" value="eIF3e_su6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01186">
        <property type="entry name" value="eIF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00088">
        <property type="entry name" value="PINT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="Winged helix' DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50250">
        <property type="entry name" value="PCI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCI" evidence="6">
        <location>
            <begin position="305"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR016255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="526" mass="60729" checksum="1ADEF6CB83C3CEB8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G8W5</accession>
    <name>A0A8T0G8W5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Ubiquitin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G033900</name>
        <name evidence="15" type="ORF">KC19_1G237600</name>
        <name evidence="14" type="ORF">KC19_4G255800</name>
    </gene>
    <organism evidence="13 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the 60S subunit of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Part of the 60S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the ubiquitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G8W5"/>
    <dbReference type="OrthoDB" id="1649877at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01803">
        <property type="entry name" value="Ubl_ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000014">
        <property type="entry name" value="Ubiquitin-60S ribosomal L40 fusion"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.50:FF:000001">
        <property type="entry name" value="ubiquitin-60S ribosomal protein L40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_eL40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="Ribosomal_eL40_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019954">
        <property type="entry name" value="Ubiquitin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019956">
        <property type="entry name" value="Ubiquitin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050158">
        <property type="entry name" value="Ubiquitin_ubiquitin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10666">
        <property type="entry name" value="UBIQUITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01020">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00348">
        <property type="entry name" value="UBIQUITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00299">
        <property type="entry name" value="UBIQUITIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1017">Isopeptide bond</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="12">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00035124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0553722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0581483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0592262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14717" checksum="8E4EA06B33699971" modified="2022-10-12" version="1">MQIFVKTLTGKTITLEVESSDTIDNVKTKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGIIEPSLMALARKYNQEKMICRKCYARLHPRAVNCRKKKCGHSNQLRPKKKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9I1</accession>
    <name>A0A8T0G9I1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G190700</name>
        <name evidence="3" type="ORF">KC19_VG001700</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9I1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0571317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="109" mass="11127" checksum="45A1F75D61EBCB62" modified="2022-10-12" version="1">MLRGPIPGTVSRSGRGSCACRATPAPNDLLLRSRTLPARSTSATTTSTSPPTLAPPLPLSPASTSRTAAPSPSTRSPAKLSSKSSLSPTLSPTLSPKTLEVLTPRARLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9I6</accession>
    <name>A0A8T0G9I6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G109000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009646">
        <property type="entry name" value="Root_cap"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31656">
        <property type="entry name" value="ROOT CAP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06830">
        <property type="entry name" value="Root_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035908873" evidence="1">
        <location>
            <begin position="32"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="456" mass="49167" checksum="B4C9212B3AE7C4CD" modified="2022-10-12" version="1">MIMAPSLRMISTLAPVTLTFLVLCTTLVVHAAPIVPDNCPTGCDQFPGSLGATFLFGDLATPLGYKQVTAICPGTEQARDCQRIASPPDVYDQVAPTFRCCDKFRIATGSHFFQTSVDITNDENIRVSQYRSSRRTEQLDWQDNQYIGCNEGSPVDNPYQQVIFDSPVVIPVGSPVGINYTRITEIEACYYPYNGPLPPPPPPPGSVTGDPKVVGGDGVVFYFHGRKDHDFCLVSDSDLHVNAHFIGKRPAGRTRDFTWVQALGFVDGSHTLTIAAKRVANWDSAIDHLEFIYNGEALALNLESLWTSPGGVMTLKRTNATNSVDLEIKEKMGVSLNAVPIGKHESDVHHYGITSDDCFAHMDMQFRFYNLSAAVDGVLGQTYQPGFVNPVTRGVAMPVMGGADRFASSSLLATDCAVSRYTATAAVLVSATPSLAAACGSSGLAHGFPGGITCRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB02</accession>
    <name>A0A8T0GB02_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase subunit 4L</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_12G148500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB02"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035798104" description="NADH dehydrogenase subunit 4L" evidence="2">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0555159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="50" mass="5575" checksum="9169187636CAB845" modified="2022-10-12" version="1">MCYGLCGMLLLFMMCRCVALSGLVQCLTFIFLVGDVFICVYIELSPVKNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB81</accession>
    <name>A0A8T0GB81_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G043900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB81"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044974">
        <property type="entry name" value="Disease_R_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11017:SF579">
        <property type="entry name" value="TIR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="16"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="951" mass="109073" checksum="F6AF74A082B861A6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GC35</accession>
    <name>A0A8T0GC35_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pectate lyase</fullName>
            <ecNumber evidence="3 8">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_12G120300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion. Required for its activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="3 8"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GC35"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018082">
        <property type="entry name" value="AmbAllergen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF187">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00544">
        <property type="entry name" value="Pectate_lyase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00807">
        <property type="entry name" value="AMBALLERGEN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035968958" description="Pectate lyase" evidence="8">
        <location>
            <begin position="23"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Pectate lyase" evidence="9">
        <location>
            <begin position="151"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0554802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="430" mass="46855" checksum="86FADA798606AEB7" modified="2022-10-12" version="1">MERLGLFLCLLVLAGSFDEMSAHFRDDYDTIIQAYASTKPVEDWDVTIQYPKPARAREYNIQPGEEVDVGSSRDKGNPIDDCWRSDPNWPYNRQALAYCGVGFGAKAMGGANGPIYVVTDDTDADLVNPAPGTLRYGVLQDGPLWIGFSRDMNIKLQNELIMTSFKTIDGRGFSVHISGGAGLTLQYISNVILHGVHIHDLKATGPAVIRSNVTHVGHRKGSDGDAVNIFGSRDIWVDHCYFARGPDGLVDAVMGSTAVTVSNNYFEQHDKVMLFGAHPYDTMDQGMQITVAFNHFGRGLIERIPRVRHGNVHVLNNFYEGWGMYAIGGSEGPTIVSEGNIFNAPDTNDKQVTKRIDDGDPDYKQCLSWNWLSEGDLFLNGAYFVSGGAAPGSYVYSKAVSTASRVPVDKVGAITRDAGPLACSPNAGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE12</accession>
    <name>A0A8T0GE12_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_11G115500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TALE/KNOX homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GE12"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005539">
        <property type="entry name" value="ELK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005540">
        <property type="entry name" value="KNOX1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005541">
        <property type="entry name" value="KNOX2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03790">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03791">
        <property type="entry name" value="KNOX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01188">
        <property type="entry name" value="ELK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01255">
        <property type="entry name" value="KNOX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01256">
        <property type="entry name" value="KNOX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51213">
        <property type="entry name" value="ELK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0371">Homeobox</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELK" evidence="9">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Homeobox" evidence="8">
        <location>
            <begin position="434"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox; TALE-type" evidence="5">
        <location>
            <begin position="435"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="218"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="495"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="244"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0557270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="59516" checksum="628611B7A7B4700D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GF68</accession>
    <name>A0A8T0GF68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_11G119600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GF68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.2220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002893">
        <property type="entry name" value="Znf_MYND"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01753">
        <property type="entry name" value="zf-MYND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144232">
        <property type="entry name" value="HIT/MYND zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01360">
        <property type="entry name" value="ZF_MYND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50865">
        <property type="entry name" value="ZF_MYND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="MYND-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0557315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="28904" checksum="561E47F360A6327B" modified="2022-10-12" version="1">MEGVNVDDVRSTQCYNTGCTNPGPNRCAGCKVVRYCSKACQRAHWPAHKHICRNGVVKPEVDERSGERSRVINNAVRILPGHFSDRESLRQLVKPFRMQSWRQENPDEEGECREIKQKFGWGKVVDGGKCYDHKGTDTWYYLIYIDPTKRTRTPRNEVVELVTERRPEHSKETFVRHGHGPVHGEAVWIRSGPKGNFTPEEILIDDVLDTILYYQTHPPLTVWHERESSRFVRMTAAKIGVDPTKLRYFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFI6</accession>
    <name>A0A8T0GFI6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">catalase</fullName>
            <ecNumber evidence="2">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G014600</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the catalase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="2"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042542">
        <property type="term" value="P:response to hydrogen peroxide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08156">
        <property type="entry name" value="catalase_clade_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.180.10:FF:000001">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.180.10">
        <property type="entry name" value="Catalase core domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040333">
        <property type="entry name" value="Catalase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024711">
        <property type="entry name" value="Catalase_clade1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11465:SF9">
        <property type="entry name" value="CATALASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038928">
        <property type="entry name" value="Catalase_clade1-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="Heme-dependent catalase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0349">Heme</keyword>
    <keyword evidence="8" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase core" evidence="12">
        <location>
            <begin position="89"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="10">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR038928-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0555942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="577" mass="63957" checksum="19A17C2F907456D3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHG1</accession>
    <name>A0A8T0GHG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_11G174500</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0558035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHG1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000178">
        <property type="entry name" value="serine/threonine-protein kinase PBS1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019825">
        <property type="entry name" value="Lectin_legB_Mn/Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00307">
        <property type="entry name" value="LECTIN_LEGUME_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0430">Lectin</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="11 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0675">Receptor</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="329"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="20">
        <location>
            <begin position="392"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0558035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="701" mass="77322" checksum="20322BFF3A883472" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHJ1</accession>
    <name>A0A8T0GHJ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Peroxisomal nicotinamide adenine dinucleotide carrier</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G002000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHJ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006862">
        <property type="term" value="P:nucleotide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044712">
        <property type="entry name" value="SLC25A32-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45683">
        <property type="entry name" value="MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="122"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="222"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="127"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="8">
        <location>
            <begin position="254"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0558065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="366" mass="39323" checksum="CD3FF5F1F2B062F1" modified="2022-10-12" version="1">MSDAVVNGLAGAGGGIVSLVLTYPLLVVNTRQQTERKAKANNGELDVDAVLSSNASSKLTVPTGTVQEIFKVIRTEGWGGLYRGFMPSLLGTAFLQGAYYYFYQLLRNEAEARAQKSKKLGYADASVGMLTSLVIATVAGCANVLLTNPIWVIVTRMQTQAQAQKRSEMAKNNKNKTSSGYFVSPSVDLATASNLSNSSPSTAGQGTLDTVKDLYNEAGVRGFWKGVLPSLIMVCNPAVQFMLYEITSRGVKHVSASEVFLLGAIAKLGATVVTYPLLVVKSRLQAKQEIGDKYLQYSGTLDAIVEMLRFEGVTGFYKGMSTKIVQSVMAAAILFMIKEELVKAARALITKQVKIPKMAKLKAAST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ33</accession>
    <name>A0A8T0GJ33_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Crinkler (CRN) family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G107300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ33"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0559471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="609" mass="69106" checksum="24868B7106BD7861" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJF8</accession>
    <name>A0A8T0GJF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">O-acyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_10G017900</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Endoplasmic reticulum membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027251">
        <property type="entry name" value="Diacylglycerol_acylTrfase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004299">
        <property type="entry name" value="MBOAT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014371">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408:SF7">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10408">
        <property type="entry name" value="STEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03062">
        <property type="entry name" value="MBOAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000439">
        <property type="entry name" value="Oat_ACAT_DAG_ARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500231">
        <property type="entry name" value="Oat_dag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 11 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="207"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="370"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="498"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="35"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000439-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0558309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="527" mass="60429" checksum="A407CF0237503617" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKK1</accession>
    <name>A0A8T0GKK1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Myb-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G143000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKK1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492:SF11">
        <property type="entry name" value="OS04G0670900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33492">
        <property type="entry name" value="OSJNBA0043A12.37 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="42"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="145" mass="16199" checksum="2159452168F3CDBB" modified="2022-10-12" version="1">MDRNLLSQGCTVPGSMSWLRSPSNVPQSSSQPEDPSQSEFFDLNDVDPSQNDEDDCEMGEPQGDTVPGRVYKKGPWNTSDLMVLLAVKKIDWFTYGPGTGSKALHKPGHERWALISENCFQQNISRSGQQCQDKFEGVRGDFQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKU8</accession>
    <name>A0A8T0GKU8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G059100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0558854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="149" mass="15885" checksum="ED8F4CF26AEB1A51" modified="2022-10-12" version="1">MELGRRQSSIRWAGVVFGVLLVAVAMVGGVGAVEPGSGGQQQSAGETAKQVQAVLGQVWELVGPWVQWAKSIGRDLFAVVYERASLQGLKSVAAEAGRIGFDFFSGRPYQAAYEVARDVPGVGRAVKEVVGEANLRKKAAREKAEEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GN24</accession>
    <name>A0A8T0GN24_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endoplasmic reticulum transmembrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G026100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the BCAP29/BCAP31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GN24"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008417">
        <property type="entry name" value="BAP29/BAP31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701">
        <property type="entry name" value="BCR-ASSOCIATED PROTEIN, BAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12701:SF18">
        <property type="entry name" value="ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="1" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="1" id="KW-0653">Protein transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035886696" description="Endoplasmic reticulum transmembrane protein" evidence="3">
        <location>
            <begin position="17"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="110"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU367026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="232" mass="25389" checksum="6D0A23012567134B" modified="2022-10-12" version="1">MLPLLVAAAGAEAVVAFLLASRVTPLVEGGNAVVEVCRRNKAARVLVKTATGAFVVRLASDVSSALRLQRRVAVADQLLAQTQLLEIALICFVLILELAVNSLYLSLKRAAGLKQEVDSLKKQLKGAQAAYVKLQDEVSLKAAKEENRLAVEVKSQKEIIFDLRQKLEQAQVDANSKEKELKSATTNLKALEKQTGGFQDEYMRVLDDNENLRNQLSLFDRKNASSGNKKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPQ1</accession>
    <name>A0A8T0GPQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD-dependent epimerase/dehydratase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G123400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPQ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000321">
        <property type="entry name" value="Chloroplast stem-loop binding protein of 41 kDa a, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725:SF6">
        <property type="entry name" value="CHLOROPLAST STEM-LOOP BINDING PROTEIN OF 41 KDA A, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43725">
        <property type="entry name" value="UDP-GLUCOSE 4-EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD-dependent epimerase/dehydratase" evidence="1">
        <location>
            <begin position="97"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="416" mass="44745" checksum="6904F45AD7815AE3" modified="2022-10-12" version="1">MAMAQSIASLSLGATAQLQGTSASGSAASGSARPSLSLRSNATGFSSQAHFTGSFGLSWSVQGNGLSRSERRHGAVLAVRAAAGEKKNVLIVNTNSGGHAVIGFWTAKDLVAAGHSVTILTVGEESSDKMKKQPFSRFNELREIGVQTVWGEPSDLGAALGNIQAPFDVVLDNNGKTLDVVQPVADWAKANGAKQILFISSAGIYKSSFEQPHVEGDAVKEDAGHKLVENYLADLGLESWASFRPQYMTGDGNNKDCEEWFFDRISRDRPVCIPAPGIQVTNISHVRDLSSMLTLAVEKPEAANGSIFNCCSDRGTTFDGLVKMCAKAAGKEAKIVHYDPKAAGVDAKKAFPFRNMHFYAEPRAAKTKLGWESKTNLAEDLKERYQEYVKIGRDKKDIKFELDDKILEAVSEPVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQV5</accession>
    <name>A0A8T0GQV5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G099800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQV5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="60" mass="6576" checksum="A2BF14225756C74E" modified="2022-10-12" version="1">MKMEGMQPCGSVKDRVGFAIIEDAEAKGLIQPGKVRPRDAFSDRFQKIDSASPNTTISYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTU8</accession>
    <name>A0A8T0GTU8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Leucine-rich repeat-containing N-terminal plant-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_9G075600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Leucine-rich repeat-containing N-terminal plant-type" evidence="3">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0561584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="104" mass="11157" checksum="649E56B327E60F98" modified="2022-10-12" version="1">MLVCELAVNAMQAILGAWNTSTPHPESNLAGWNSSQIFPCEQEYVNGNPNWRGVQCLTHINCHPKVNSSDIDCSAFIVGLTLQSASITGILPSEIGNISTLTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV62</accession>
    <name>A0A8T0GV62_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">KC19_8G046800</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV62"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002229">
        <property type="term" value="P:defense response to oomycetes"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000240">
        <property type="entry name" value="Lectin-domain containing receptor kinase A4.3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000015">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050528">
        <property type="entry name" value="L-type_Lectin-RKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27007">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0430">Lectin</keyword>
    <keyword evidence="13 17" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0675">Receptor</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 17" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 17" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="17">
        <location>
            <begin position="346"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="18">
        <location>
            <begin position="402"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG0563631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="775" mass="86898" checksum="C136B9C35849690C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX97</accession>
    <name>A0A8T0GX97_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe-S metabolism associated domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G049000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX97"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.90">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002634">
        <property type="entry name" value="BolA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036065">
        <property type="entry name" value="BolA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46230:SF3">
        <property type="entry name" value="SUFE-LIKE PROTEIN 1, CHLOROPLASTIC_MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01722">
        <property type="entry name" value="BolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82657">
        <property type="entry name" value="BolA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82649">
        <property type="entry name" value="SufE/NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S metabolism associated" evidence="1">
        <location>
            <begin position="75"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="35977" checksum="05283C4EFACBBCDD" modified="2022-10-12" version="1">MATAAPVMAMAASMSRFFQDGSQAKPWVSTCCFRDLQGGSRSGASRRLSCRASSSWSQGAERSELPEKLQEIVRVFQGVTEPRAKCEQLLHYAAKLKPLAEEQKQPENKVEGCVSKVYIVCEFNEADGRVYFEAESDVMLTKGLAGLLVEGLSGVTVEEVLKVTPDFVHMLGLKQSLTPSRSNGFLNMLKLIQKKTLQVYSNATPTVAGNATVPITSIDPHNDLPHLTPSPGGPQTKKHLIEKKLTEGLTPVQLEVQDVSHEHAGHEGGPRGSPETHFHVKVVSEQFQGRSLLKRHRLVYELLQAELREGSVHALSICTKTPTEVAAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXP9</accession>
    <name>A0A8T0GXP9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G192200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0563039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXP9"/>
    <dbReference type="OrthoDB" id="417891at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.720:FF:000084">
        <property type="entry name" value="Short-chain dehydrogenase reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045000">
        <property type="entry name" value="TR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898:SF6">
        <property type="entry name" value="NADP-DEPENDENT MANNITOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42898">
        <property type="entry name" value="TROPINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13561">
        <property type="entry name" value="adh_short_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0563039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="278" mass="29312" checksum="101EEEA98DD11416" modified="2022-10-12" version="1">MAMSPGAGEGPSAPSSSALAARWNLQGKTALVTGGTRGLGRAIVEELAGLGVSVYTCARSKESLSSSLESWRQAGLLVQGSVCDLSVRGAREELFRSVRAHFGDALDILVNNVGTNVRKPTVDYTGEDFSFLMSTNLESAYHCSQLGHPLLKASGNGTLVFISSVAGVTAIRSGTLYAATKGAMNQITKNLACEWAKDGIRVNSVAPWYINTDLAQQVLANADFRAEVLSRTPLRRVGEPHEVAGLVAFLCMPAAAYITGQIISIDGGMTVNGFYLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GYG7</accession>
    <name>A0A8T0GYG7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G035700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Endomembrane system</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the methyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GYG7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000728">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004159">
        <property type="entry name" value="Put_SAM_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108:SF1058">
        <property type="entry name" value="METHYLTRANSFERASE PMT18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10108">
        <property type="entry name" value="SAM-DEPENDENT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03141">
        <property type="entry name" value="Methyltransf_29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0563495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="636" mass="71758" checksum="A0BA8225A1416555" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0N5</accession>
    <name>A0A8T0H0N5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G105000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0N5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="145"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="184"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="214" mass="23338" checksum="6953B71DF43B2938" modified="2022-10-12" version="1">MLHSPGVQGSSYSPIRSALFVFLTQQPPGPFFPRTTMPGSPCRTMYLCPPKNSPFCASTLFSSNPSRSFSISPAFNSGKVALCAQMLPSWPTMAAANSECPGEISYIRWSSTYTCQDMIAAGFSPSRSAQLQLNITTRKHLHQKPSPTSTQTPPITAHTQTTNKNPTLTSHHPIQLHTPPNPTKRGTSNNKKPKITFTSTTMYTQPHVRSTKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0U7</accession>
    <name>A0A8T0H0U7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Haloacid dehalogenase-like hydrolase domain-containing protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G103000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H0U7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd16415">
        <property type="entry name" value="HAD_dREG-2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.720">
        <property type="entry name" value="Haloacid dehalogenase-like hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011949">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044924">
        <property type="entry name" value="HAD-SF_hydro_IA_REG-2-like_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02252">
        <property type="entry name" value="DREG-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47105">
        <property type="entry name" value="OS02G0173600 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47105:SF1">
        <property type="entry name" value="OS06G0665100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="283" mass="31670" checksum="79457C416C50534B" modified="2022-10-12" version="1">MVRKSIIHAATSGGHALLKQAVRAPTQPLKCVTVDVTGTLMGYKGALGDYYCMAAKRAGLPCPDYERMHQGFEVAYKEMDQMYPCFGKIHNVPNQEWWRECVRKAFCEAGYDYTDKEFDAVFLRIYGIFGSSAPYEVYDDVIPFLRWVRAQGIVVGVLSNASYRYRDDILPQLGIKQGEEWDFGVFSGIEGVEKPNPEIFKIALSRAGSNIIPEQALHIGDSLRKDFVPAATLGMHALLLNRFDSKEARAAKETGVPVVTDLRQCQDYIVALREESKASQPIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H0Y3</accession>
    <name>A0A8T0H0Y3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_8G112700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03233">
        <property type="entry name" value="ABCG_PDR_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034001">
        <property type="entry name" value="ABCG_PDR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040:SF13">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040">
        <property type="entry name" value="PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="562"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="649"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="674"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="755"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1222"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1255"/>
            <end position="1271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1303"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1338"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1368"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1395"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1449"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="160"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="879"/>
            <end position="1131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="796"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0564467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1480" mass="166573" checksum="8ECE70052968BB49" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H231</accession>
    <name>A0A8T0H231_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Red chlorophyll catabolite reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G140000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H231"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051743">
        <property type="term" value="F:red chlorophyll catabolite reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015996">
        <property type="term" value="P:chlorophyll catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009439">
        <property type="entry name" value="RCC_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34685:SF2">
        <property type="entry name" value="RED CHLOROPHYLL CATABOLITE REDUCTASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06405">
        <property type="entry name" value="RCC_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="321" mass="34997" checksum="B84B385D53137D94" modified="2022-10-12" version="1">MASALASPSACLRITQRSHQRSPRQCNWSQLGCAQGQTNRRGLKWMVRGSVSEASMAKETSWVEFPKLSPAGKQLMETVAETMNRELGDMILPSQTASDVRSFQGGNGAGSVTLRAGREGSKIDFVLGSWLNCALPFGELNIATLIAMLGPEADSPHLLFEFIQSGPGSLVLVLDLLPRKDLVLEPEYLARYYENSPLETIRQSFEKHPQAQPYLTSALYVRSVVSPTAVLYKVSGEGVEGGLDGVIAELVQPAALKVVETWLDCYKNVGEDLHGDAVAAMKKRDELIKSMGVEVDLSANMPRLFGQEIADRVVEAFRKGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3D0</accession>
    <name>A0A8T0H3D0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G179200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3D0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11797" checksum="430303F46A4DBBC5" modified="2022-10-12" version="1">MKHQGSLMSPKITMAELTHSRSKNSLLLNNSSEASISSTFKPISDYVGCSPNDLIYIYITSTASLKCSTKSTVRRCTSVLTINFLLSARLSYCCMLVHIENITLSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3K3</accession>
    <name>A0A8T0H3K3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphate transporter PHO1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G014400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SYG1 (TC 2.A.94) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3K3"/>
    <dbReference type="OrthoDB" id="9970435at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005802">
        <property type="term" value="C:trans-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000822">
        <property type="term" value="F:inositol hexakisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016036">
        <property type="term" value="P:cellular response to phosphate starvation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004342">
        <property type="entry name" value="EXS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004331">
        <property type="entry name" value="SPX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783:SF103">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 53 MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10783">
        <property type="entry name" value="XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03124">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03105">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51380">
        <property type="entry name" value="EXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51382">
        <property type="entry name" value="SPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="448"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="490"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="538"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="741"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="788"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="SPX" evidence="9">
        <location>
            <begin position="2"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="EXS" evidence="8">
        <location>
            <begin position="676"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0565783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="865" mass="97946" checksum="69B86083C073DE18" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5C1</accession>
    <name>A0A8T0H5C1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G114400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5C1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017930">
        <property type="entry name" value="Myb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006447">
        <property type="entry name" value="Myb_dom_plants"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046955">
        <property type="entry name" value="PHR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001005">
        <property type="entry name" value="SANT/Myb"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01557">
        <property type="entry name" value="myb_SHAQKYF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314:SF164">
        <property type="entry name" value="HTH MYB-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31314">
        <property type="entry name" value="MYB FAMILY TRANSCRIPTION FACTOR PHL7-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00249">
        <property type="entry name" value="Myb_DNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51294">
        <property type="entry name" value="HTH_MYB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH myb-type" evidence="4">
        <location>
            <begin position="38"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0567146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="271" mass="30710" checksum="A4183AF354327C2A" modified="2022-10-12" version="1">MGVLAANHSREKRRVLIPMSTAASIAELKRNYVRPYVRTSTHKLRWTKDLHQSFMDAVTLLGGKDKATPKQILALMKRDDVTIAHVKSHLQMYRQDKINAEGMPVNADDPVLFKPISKALSRISPEQQKDELSPGAPRDEVYMALQLLKEGKITEVQNFLIRRMPDYQRYATMAPEGDTKSEDVKPREFITEVVSPTERKRKAEDVQTHEFITEVVSHTEKKRKAEDNVELDLSLAPTSLSCPSIRSPRLRLPSPSTAEEATLSLGLFVDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5F5</accession>
    <name>A0A8T0H5F5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G198300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5F5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035773034" evidence="1">
        <location>
            <begin position="23"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0565539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="51" mass="5774" checksum="164FD129ACAD14B8" modified="2022-10-12" version="1">MLVMLMLCQSFLFLVACTGILGKSHVNTRVAHQVFSFTEVVQYSCKTIQHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6L4</accession>
    <name>A0A8T0H6L4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_7G101600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the XPO2/CSE1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6L4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000057">
        <property type="entry name" value="Exportin-2 isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005043">
        <property type="entry name" value="XPO2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013713">
        <property type="entry name" value="XPO2_central"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF8">
        <property type="entry name" value="EXPORTIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03378">
        <property type="entry name" value="CAS_CSE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08506">
        <property type="entry name" value="Cse1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="8">
        <location>
            <begin position="29"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0566983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="963" mass="108563" checksum="A760ED4318DA3E58" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAB0</accession>
    <name>A0A8T0HAB0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G125200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAB0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="197" mass="23241" checksum="F89785D206D2DEC2" modified="2022-10-12" version="1">MVQIQPQPKPRARAPERHPLRLLHGVAVRRILHGRRPGALPPALAVGAPYRDAVHHRHRRAVVREHDAAHLPAPPRRVEAQHPIRVVPRNVLQHHALVVARLQHLVRHPLVHVAQYLRQRPRYQRRLLGRLQRHGVARIRHRLPPAIHRHHPHPHPHPHPPHPHPHQPPLPQRHPAQRRPRHRHSHRHSHNRTDNWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HAW4</accession>
    <name>A0A8T0HAW4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G051300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HAW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="132" mass="14774" checksum="92864B49FC40231A" modified="2022-10-12" version="1">MLQIQALSSNSIVLITDEDGNGGQYAAHGLGFEERVSVRDFASFGVLAVAFAAASLQRRLPCWWRCCPVCRFACLRHNEHLHSSPKQLYQACKSQSSGPTLVYEFGPTYMREQSVTQTDVLKEREPERTTCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HC76</accession>
    <name>A0A8T0HC76_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CNNM transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_6G063800</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HC76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:intracellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010960">
        <property type="term" value="P:magnesium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.580.10:FF:000015">
        <property type="entry name" value="DUF21 domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="entry name" value="CBS-domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045095">
        <property type="entry name" value="ACDP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064">
        <property type="entry name" value="METAL TRANSPORTER CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12064:SF97">
        <property type="entry name" value="METAL TRANSPORTER CNNM-5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="CBS-domain pair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 7 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="10">
        <location>
            <begin position="25"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="320"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0569073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="53953" checksum="D50891395B7E17EB" modified="2022-10-12" version="1">MVFVGVLGVGRAIRSMVGDEPSPYMQPWWWIWAGISVCLVLFAGIMSGLTLGLMSLGLVDLEVLQQSGSDEEKRQATRIMPVVQKQHELLVTLLLCNAAAMEALPIFLDDMFNEVVAVLLSVTFVLAFGEVIPQAVCSRHGLAIGADMIWLVKILMVICWPISYPVGKILDHLLGHNDSALFRRAQLKALVSIHGREAGKGGELTHDETTIIRGALDLTEKTAMDSMTPIESTFSLDVHSKLDWEVLGKIMARGHSRVPVYEGSPRNLIGVLLVKSLLTVRAEAEIPVSAVSIRRIPRVPSDMPLYDILNEFQKGGSHMAAVTKPKTKKKNAHANDLNGDDKPETTDTNAEADLERGVSDQLHEYESKLFEENGDDFDDLSDGEVLGIITMEDVMEELLQEEIVDETDEYIDVHKKVRVAAAAAHHVTRGGSMLVRKVGSLRYPQQMGLSKQGQQAVNKIRQVEKDAREEQLATNGLNGDTLTLPLLNDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCW4</accession>
    <name>A0A8T0HCW4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G105300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCW4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="88" mass="10437" checksum="E077753F6909CD58" modified="2022-10-12" version="1">MRPAYKLFPNNFIEVGSYWTAFSPVQLQVRLILNFVQNERECPRNGRGFLFQRCNYCSQNKMIICCTIMKCIYSLQLLIFGRAFKLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEP2</accession>
    <name>A0A8T0HEP2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G089800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEP2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0569425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="17341" checksum="4642F97DE1A316FC" modified="2022-10-12" version="1">MTNWHEATTSRPPKCRLPPPTHFNSDSNLENKTDDEYGHTKLMINSSMLQIPRNSRDAINDLPTKFCSGGESPHHLNQSQLGSPLQARALSTEIYSSWTKYVTGENSITATPTWSSVNFNQSPGLEYCNSYKDLEVRPTSTYKAADQPPQHLWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI01</accession>
    <name>A0A8T0HI01_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G134700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI01"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0052">Apoplast</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035959942" description="Germin-like protein" evidence="10">
        <location>
            <begin position="32"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="11">
        <location>
            <begin position="75"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="41"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0570039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="232" mass="24728" checksum="3637980176507583" modified="2022-10-12" version="1">MGKSTSSTQALLSKLLIIALCATTFFVAVHAADPDPLADFCVADLSPNAPRVNGFACKPRSNVTTDDFVYSGFRQAALSDAEISQTPTGAIVGLTNLRDWPGANTQGVTHARLDFAIGGVIPFHTHPRASETLLVLKGTVYTGFISDFNVLYASTLKQGDVIVFPRALLHFQLNVGNETAITFNTLTSQNPGFLDSVNQIFEPNITSAVIEKSFGIDAATVKLLKGSYPGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HII8</accession>
    <name>A0A8T0HII8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pentatricopeptide repeat-containing protein-mitochondrial domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G090200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HII8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044605">
        <property type="entry name" value="At1g26460-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002885">
        <property type="entry name" value="PPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057027">
        <property type="entry name" value="TPR_mt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00756">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47205">
        <property type="entry name" value="OS07G0599000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47205:SF1">
        <property type="entry name" value="OS07G0599000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13041">
        <property type="entry name" value="PPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13812">
        <property type="entry name" value="PPR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23276">
        <property type="entry name" value="TPR_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51375">
        <property type="entry name" value="PPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="162"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Pentatricopeptide repeat-containing protein-mitochondrial" evidence="3">
        <location>
            <begin position="348"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="repeat" description="PPR" evidence="2">
        <location>
            <begin position="503"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="637" mass="69446" checksum="32FA5C88AECDED3A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HKG8</accession>
    <name>A0A8T0HKG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Histone-lysine N-methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_6G223300</name>
        <name evidence="9" type="ORF">KC19_VG001000</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HKG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15515">
        <property type="entry name" value="PHD1_KDM5A_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10539">
        <property type="entry name" value="SET_ATXR5_6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053114">
        <property type="entry name" value="ATXR5/ATXR6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442:SF1">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="289"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0571258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0571310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47740" checksum="636259F414C88A58" modified="2022-10-12" version="1">MEDEECGRGRRVERVIVCRNGWHHCCLPEFEKTGPCGMHFEVSPGQTRVEVVDAGSVTESTQSVVKAKEPRSKEVVEVQEGALEFATPGGRAASKAKDAEPKEDKYDTTLCEECSRGDGEQEMLLCDSCDRGYHMYCLSPILPTVPPGEWFCPKCAESSLVQEFPKVQKKIVDFFRIQKPAPFTTETKCIGTRKRRRPSGGTLCRQKKSRRLLPYVPCTDPQRRLEQMASLATALTSIGVEFTDSLSYGLAPRSANRAEYEKGGMQVMGKEDRATLDLCKTMCSQGEWPPLMVTHDSRQGFVVEADRNIKAMTIIAEYTGEVDYMCRRRYDSGNSIMGLLFTEDPAKELVICPDRRGNIARFVSGINNHTSEGRKKQNVRCVRYNIDGEARAILVAIRDIPEGERLYYDYNAYRTEYPTEHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HM22</accession>
    <name>A0A8T0HM22_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Formamidopyrimidine-DNA glycosylase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG053800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HM22"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000703">
        <property type="term" value="F:oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="entry name" value="MutM-like, N-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="FPG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42697">
        <property type="entry name" value="ENDONUCLEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42697:SF1">
        <property type="entry name" value="ENDONUCLEASE 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="N-terminal domain of MutM-like DNA repair proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formamidopyrimidine-DNA glycosylase catalytic" evidence="1">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0571920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14926" checksum="A2901F911911C52F" modified="2022-10-12" version="1" fragment="single">MVEGPLLHRLAFAHRKLLFGQKFTATSPTGHFADGAAVIDGLFVSHIEVYGKNFFYFFTRERVGEISVLEKVGDSASSSPLEEAVVVHMHLGMSGSFRTYKCPGPVPREATRLRMYNEELGVEAHLSAMVCDYGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMZ1</accession>
    <name>A0A8T0HMZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG072400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0572145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="11232" checksum="28647FFB4BC8FDD2" modified="2022-10-12" version="1">MSNSNIVYSTRDDAPTSIRFWNSTEVRLNVTYPKPRPQSILIHRISTHYENSIVHFFDLCRIQFLEANKCLISNRIDILAQILCDPTSCTRTCSQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HNC5</accession>
    <name>A0A8T0HNC5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG086200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0572336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HNC5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="176"/>
            <end position="491"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0572336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="491" mass="57407" checksum="322C906215E68F77" modified="2022-10-12" version="1">MPKNKKQKNVGEWANQSDDMPSLRCRDYMVAFIVEFYQENILVSLNSRYVRYGEDGPRKFKSEMETKIRDRLMDPCWHSDTQKPGYDHFVSQRAHDALWNAKEVITKYAKAQRGGVQAFKDTIAKADFFTRLMAPLNSRKHRRASITWWNSPIGMETAADLRKRHLTILADFAIFYYLDKEVQRGGYATIRRVRIEGNPEIPPYWEFAEKRPLNWSMRPDLARVDHYNESLAIRIPHPGVIRFMAIHQLEHVGFMFWWNGGTLRAMLQRDNEAPGDLPIDYIFSENAEDSPILGKRLQLFRSKRTELAWALCNIIDAVHKYGYLHNDLSPDNILLHFPEDESKIYIGVCDWGLMTKTLENRRSPWVFESVHQKEETMRRRYWVDPRVVYVHKENQDIQIIPDLTVASEDFAAAKIAAKINRGNMCTAYHEAEPVETRHFQNIGELAMVFEGYLERVCQNNSGTIGGLGHLINRSRDTHNWPTPIEHYRVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ98</accession>
    <name>A0A8T0HQ98_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Vasohibin 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG152000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ98"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028131">
        <property type="entry name" value="VASH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750:SF2">
        <property type="entry name" value="VASOHIBIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15750">
        <property type="entry name" value="VASOHIBIN-1-LIKE ISOFORM X2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14822">
        <property type="entry name" value="Vasohibin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR628131-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0573140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="472" mass="52046" checksum="42FACFBA1475D999" modified="2022-10-12" version="1">MLERSPVIQEESVAAHVDSSLLGLGSAALMSKKPRVPENFNNLLTKPRLKALKQYIGSFQYRLNSQTNFNAHKLRPLAQIMDTARMIVYAPQPIKCVEAVFVALYLTAGLPDVERVPLGFKTELSGQVYQHIVLLVQHGSKWGAFGISRCPDLMNKDLMFDSMSSVIENFKAAYELQGHIVLKVRVGLPVEHSNTSPNFVCWRHLNLNLRYTSWSDVIYFALALIINFIAFVSRDSPFQCVDEIDNHAARGKRLWDLWILSGKGEDPHKSSAIRKAPLDTKEKMKKLSSRDAIVTSEASSSSELNTSSGVCSLSIINAGTSKLEEETTTVVAEPEAESTLKCLETTLVAPCPGTVGNSKFRSRTKIGQPSSSSAETGDAAKGTKLMRAATMLPRSIAGIIIDQMLTVSRGFLRKKYFQGTAGNGGKRMSRPKTLPSSRQMVVVGTNPLFTRKPIHISHQTPNAETLVRKSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQP9</accession>
    <name>A0A8T0HQP9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG166600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQP9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035740492" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="70" mass="8232" checksum="216BB1911686148F" modified="2022-10-12" version="1">MSMFEVCTHLFFVLVLLLLPSLGTLPEAFSVSARHWIRQFDPCFVHVVGEYRVDVRRQTYISTYLRVLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HRQ8</accession>
    <name>A0A8T0HRQ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG181200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HRQ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="6979" checksum="5E672E5D558B4FD7" modified="2022-10-12" version="1">MSSWRHCDGRFQCILRYVNSWLKCIKRVCHSKQPFLPFADNANEYGIRAKLKIMISGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HSJ4</accession>
    <name>A0A8T0HSJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG205500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HSJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0573741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="10902" checksum="5348EEC33AF3EDC2" modified="2022-10-12" version="1">MISNLQRPQGFSQGSSIEAHALEDFIGEDPSFYMISEEGIEAAFAALSLDSATDQDLILDSGASRHFANDPNLFRTLDQGSSQGVVTSASRQDHVIKGTGNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTF7</accession>
    <name>A0A8T0HTF7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG232200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0574077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="143" mass="16034" checksum="53161705BCEF134B" modified="2022-10-12" version="1">MAVDEGVVDSPVNLSVPKTLKSPSPMWPRTVLQVLSPKQQSSTPTKRALYNNVEDMPSPPPAKMPRLRSTTTGSRARKSADSHSKPSSTRHHSLPESSIGDRRRQKLQRLLDSPMMQVEGMSWTRQRQREFVKSRIEAYGGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUT3</accession>
    <name>A0A8T0HUT3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG245600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14920" checksum="7A8D5A9B8E0827CB" modified="2022-10-12" version="1">MQYHFQKKNLNLNMGFTWPRRLLMLIATALPIERYNMPVISMHSSSTYAWQQGPQALGHLPCSLAPAFPEMHRIYPVHECPGLAQVQLRKAAQVMLRNSRREYLSLILVIPKPHQQKVSSHLCLMSLWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYC8</accession>
    <name>A0A8T0HYC8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G024700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYC8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0575699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11395" checksum="8C8D9EBCE6E16152" modified="2022-10-12" version="1">MIHSKHMVHVSIYMYLNLETYWTKWPIKGKHNITKLDYTALSALPMPAKPPVHYETAECSSYDLCGWYSQGSDTTREVTSTSCILQASGAQVPLPCSISKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZ68</accession>
    <name>A0A8T0HZ68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Polycomb protein VEFS-Box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_5G081300</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZ68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd21553">
        <property type="entry name" value="VEFS-box_EMF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21749">
        <property type="entry name" value="ZnB-Zn_EMF2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056068">
        <property type="entry name" value="EMF2-like_DUF7651"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019135">
        <property type="entry name" value="Polycomb_protein_VEFS-Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057540">
        <property type="entry name" value="Znf_SUZ12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597">
        <property type="entry name" value="POLYCOMB GROUP PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22597:SF0">
        <property type="entry name" value="POLYCOMB PROTEIN SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24663">
        <property type="entry name" value="DUF7651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09733">
        <property type="entry name" value="VEFS-Box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23320">
        <property type="entry name" value="Zn_SUZ12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DUF7651" evidence="11">
        <location>
            <begin position="74"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Polycomb protein SUZ12-like zinc finger" evidence="10">
        <location>
            <begin position="324"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="Polycomb protein VEFS-Box" evidence="9">
        <location>
            <begin position="558"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="435"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="446"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="496"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF23320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF24663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0576454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="692" mass="77888" checksum="32E8F8841CEE8C51" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZS7</accession>
    <name>A0A8T0HZS7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-methyltransferase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G058700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZS7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016461">
        <property type="entry name" value="COMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="COMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11746">
        <property type="entry name" value="O-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51683">
        <property type="entry name" value="SAM_OMT_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="O-methyltransferase C-terminal" evidence="4">
        <location>
            <begin position="39"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="135" mass="14962" checksum="52C0888527BD4404" modified="2022-10-12" version="1">MWVGTRAPQLQPLSPRILTFVESTSTSLTSSQGLPMCLNVVHLFNDEDSLKILQNCKKSLTPDGKLLIYDPVIPSEFGGESPYTGVSPMMDIALLVYGGGVDRTEEQWRSLLALAGFPNVKFICLQPQHWLIEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0S6</accession>
    <name>A0A8T0I0S6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Trichome birefringence-like N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G084900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PC-esterase family. TBL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0S6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016413">
        <property type="term" value="F:O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029962">
        <property type="entry name" value="TBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026057">
        <property type="entry name" value="TBL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025846">
        <property type="entry name" value="TBL_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285:SF48">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32285">
        <property type="entry name" value="PROTEIN TRICHOME BIREFRINGENCE-LIKE 9-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13839">
        <property type="entry name" value="PC-Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14416">
        <property type="entry name" value="PMR5N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Trichome birefringence-like N-terminal" evidence="10">
        <location>
            <begin position="168"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Trichome birefringence-like C-terminal" evidence="9">
        <location>
            <begin position="221"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="73"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF14416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0576505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="58846" checksum="7D1AC64C216D1839" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I309</accession>
    <name>A0A8T0I309_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Endoplasmic reticulum-Golgi intermediate compartment protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_5G185100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ERGIC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I309"/>
    <dbReference type="OrthoDB" id="270930at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF25">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="9">
        <location>
            <begin position="10"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="8">
        <location>
            <begin position="189"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="133"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="133"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0577832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="382" mass="43100" checksum="ED182BB5F9BCB7CA" modified="2022-10-12" version="1">MSRTGKWQAIKNLDAFPRAEDHLMQKTSSGAAVSAVGLFIMAILFVHELRFYLETVTVHEMSVDVKRGEKLPIHINMTFPALPCEVLSLDAIDMSGKHEVDLDTNIWKLRIHRDGYVLGSEYINDLVEGEHKKEEHKVGHHDEHKDGERKEGGEHAASEGHGHGHDEHGIHDGAIGMPIHSHLSQKDPQTVIKEVKKAIEDGEGCQIFGVLDVERVAGNFHISMHGLSLYVASKIFETGYEVNVSHIIHDLSFGPTYPGIHNPLDGSERILHDTSGTFKYFLKIVPTEYHHLHGEVMPTNQFSVTEYYQKMKPSDRSYPAVYFVYDLSPIVVTVKEHRRNFGHFITRLCAVLGGTFAVTGMLDRWMFRIIELMTSTTKGTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3V4</accession>
    <name>A0A8T0I3V4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G168000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3V4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF260">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035885687" description="Protein kinase domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="644"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="68"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="680" mass="77714" checksum="36E71E4C678715D1" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4K3</accession>
    <name>A0A8T0I4K3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cystathionine beta-lyase, chloroplastic</fullName>
            <ecNumber evidence="3">4.4.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cysteine-S-conjugate beta-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_5G200900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L,L-cystathionine + H2O = L-homocysteine + pyruvate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13965"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58161"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:13966"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms homodimers. May form homotetramers from two homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4K3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047804">
        <property type="term" value="F:cysteine-S-conjugate beta-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1150.10:FF:000013">
        <property type="entry name" value="Cystathionine beta-lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000009">
        <property type="entry name" value="Cystathionine gamma-synthase homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006238">
        <property type="entry name" value="Cys_b_lyase_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054542">
        <property type="entry name" value="Cys_met_metab_PP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01329">
        <property type="entry name" value="cysta_beta_ly_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808:SF50">
        <property type="entry name" value="CYSTATHIONINE BETA-LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="TRANS-SULFURATION ENZYME FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00052283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00064715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00073814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0578046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="505" mass="54061" checksum="3211965FB30E4B09" modified="2022-10-12" version="1">MKLAARAEQSRAEQSEGRRAMAMVMTMARVDAAAATASAFGGSALAAAPKLKAIASSSLHLQSYAGWSTFPLKSNRITNSFQEPGAIVKTPASTLNLAARAVSTSMGELAEGDTMWDDDIATERELQVSTQLQQLDNSFDPYGALSTPLYQTATFKQPSATEGGPYDYTRSGNPTRDALERTLAKLEGADRAFCFTTGMAALATITRLAEAGQEIVAGDDIYGGSDRLLSRISPKSGLVVKRIDTGDLDAVRAAVGPKTRIVWLESPTNPRQMISDIREISKIAHEHGALVIVDNSIMSPILSKPLSLGADIVMHSATKFIAGHSDVMAGVLAVKGESLAKEVYFLQNAEGTGLSPFDCWLCLRGIKTMALRVERQQANAQKIAEFLVAHPLITRVNYAGLPKHTGRDLHYSQCKGAGSVFSFNTGSLAVSKHVVEQTKLFSITVSFGSVKSLISLPCFMSHASIPTDVREARGLTEDLIRVSVGIEDVDDLIADLDQALRTAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4N4</accession>
    <name>A0A8T0I4N4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_5G159000</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the peptidase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4N4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06098">
        <property type="entry name" value="phytepsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000044">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.70.10:FF:000115">
        <property type="entry name" value="Lysosomal aspartic protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="entry name" value="Acid Proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.225.10">
        <property type="entry name" value="Saposin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001461">
        <property type="entry name" value="Aspartic_peptidase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001969">
        <property type="entry name" value="Aspartic_peptidase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033121">
        <property type="entry name" value="PEPTIDASE_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033869">
        <property type="entry name" value="Phytepsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007856">
        <property type="entry name" value="SapB_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008138">
        <property type="entry name" value="SapB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011001">
        <property type="entry name" value="Saposin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008139">
        <property type="entry name" value="SaposinB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47966:SF51">
        <property type="entry name" value="BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00026">
        <property type="entry name" value="Asp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05184">
        <property type="entry name" value="SapB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03489">
        <property type="entry name" value="SapB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00792">
        <property type="entry name" value="PEPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00741">
        <property type="entry name" value="SapB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="Acid proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47862">
        <property type="entry name" value="Saposin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00141">
        <property type="entry name" value="ASP_PROTEASE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51767">
        <property type="entry name" value="PEPTIDASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50015">
        <property type="entry name" value="SAP_B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="6 9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 10" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035725418" evidence="11">
        <location>
            <begin position="26"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase A1" evidence="13">
        <location>
            <begin position="78"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="12">
        <location>
            <begin position="309"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="Saposin B-type" evidence="12">
        <location>
            <begin position="371"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="109"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0577473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="501" mass="53757" checksum="351387A7C6FD04E4" modified="2022-10-12" version="1">MAMGGRVRLAVFVAVLVLICAFAEANPRTIALKRRPVSLQGVRSAAARAVHRARVLQGGNGVGEGDAVSLNNYMDAQYYGEIGIGSPAQEFTVIFDTGSSNLWVPSAKCYLSLACYFHHRYKSSKSTTYKEDGTSFAIQYGTGSMEGFLSQDDVTLGDLTVKGQVFAEATKEPGITFVAAKFDGILGLGFKEISVNRVTPVWYNMLDQKLVNEPVFSFWLNRDTSDESSGGELVLGGVDPKHFKGEHVYTPVTRKGYWQFDLGDVTIDGRTTGFCANGCSAIADSGTSLLAGPSGIVAEINQAIGATGVVSNECKMVVKQYGDQIVQLLLEQMNPGKVCTSLGLCQFAAEELSEPGIASVVDKDEALLKGNDPGCSVCEMAVVWAQNQLRQNRTKEQIDAYLNQLCERLPSPNGESTVDCNSLSSMPKVAFTIAGKTFELAPEEYILKIGDGAEAQCISGFLGLDVPPPAGPLWILGDVFMGVYHTVFDFGNTRLGFAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I569</accession>
    <name>A0A8T0I569_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G175300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I569"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03416">
        <property type="entry name" value="CbiX_SirB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1400">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050963">
        <property type="entry name" value="Sirohydro_Cobaltochel/CbiX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33542:SF3">
        <property type="entry name" value="SIROHYDROCHLORIN FERROCHELATASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53800">
        <property type="entry name" value="Chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="3">
        <location>
            <begin position="95"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="495" mass="53544" checksum="5776D709DFD57655" modified="2022-10-12" version="1">MALCLLGAPLAQTQFCSGVALSRVGRHSGVSGRFASLAWNSGSLCGVPRGVIFRERVGGAIKARGGVRLAGVRAGMLEEVANTKIPTSDGREILAFVAKPKVDGKLPVVILVHEFYGLTPEICGKADAIAREVGCIVIAPDTYRGESTKFIPKAIYLALETPQNRVDGDLDEVLAWASTLPDADISRVGLMGFCYGGGKALAYSTKYKIAKATIVVYGKPILDSDVLQNIQGPVLGIFGDKDSQFPEKMVRGFQEALDKAGVPNTISTYKNEGHAFWTNMDQIHLVDGPQRKAWIEVTSFLKDTLNVEDEHLEGATDEDAGVNLEKMSTAGRISNLNPGDGVVIVDHGSRRAQSNEMLHQFVDLYKQKTGHSIVEAAHMELAEPSISHAFDKCVEKGAKRVIICPYFFFPGRHWDRDIPALASKAAGKHAGIPYIVTAPIGLHELMVEVMTDRMEYCLSRVSGNVEECDMCKGTGRCQQLVAASADQQVQVEANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5U8</accession>
    <name>A0A8T0I5U8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein arginine N-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G202800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5U8"/>
    <dbReference type="OrthoDB" id="412876at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042054">
        <property type="term" value="F:histone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016274">
        <property type="term" value="F:protein-arginine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000167">
        <property type="entry name" value="Protein arginine N-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.160.11:FF:000017">
        <property type="entry name" value="Protein arginine N-methyltransferase 1.6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000070">
        <property type="entry name" value="Protein arginine N-methyltransferase 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.160.11">
        <property type="entry name" value="Hnrnp arginine n-methyltransferase1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025799">
        <property type="entry name" value="Arg_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014644">
        <property type="entry name" value="MeTrfase_PRMT7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055135">
        <property type="entry name" value="PRMT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11006:SF4">
        <property type="entry name" value="PROTEIN ARGININE N-METHYLTRANSFERASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22528">
        <property type="entry name" value="PRMT_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036946">
        <property type="entry name" value="Arg_N-mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51678">
        <property type="entry name" value="SAM_MT_PRMT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="7">
        <location>
            <begin position="209"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Protein arginine N-methyltransferase" evidence="7">
        <location>
            <begin position="578"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR036946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF22528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0578071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="744" mass="82240" checksum="8CBB99E1C83C0E4B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7Q8</accession>
    <name>A0A8T0I7Q8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="24" type="ORF">KC19_4G105400</name>
    </gene>
    <organism evidence="24 25">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="24" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="24">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="18">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="24">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7Q8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033612">
        <property type="term" value="F:receptor serine/threonine kinase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009653">
        <property type="term" value="P:anatomical structure morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0099402">
        <property type="term" value="P:plant organ development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000417">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000221">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase PXL1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000219">
        <property type="entry name" value="Leucine-rich repeat receptor-like serine/threonine-protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000041">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase ERECTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000095">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase GSO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF26">
        <property type="entry name" value="MDIS1-INTERACTING RECEPTOR LIKE KINASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00365">
        <property type="entry name" value="LRR_SD22"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52075">
        <property type="entry name" value="Outer arm dynein light chain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 20" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="17" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="16 21" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 20" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="25" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="10 22" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 21" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="15 21" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="22">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035933985" description="non-specific serine/threonine protein kinase" evidence="22">
        <location>
            <begin position="29"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="21">
        <location>
            <begin position="636"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="23">
        <location>
            <begin position="708"/>
            <end position="982"/>
        </location>
    </feature>
    <feature type="binding site" evidence="20">
        <location>
            <position position="737"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="23">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="EMBL" id="KAG0579542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="25">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="995" mass="111282" checksum="38BFD7FA3A3985CE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7V1</accession>
    <name>A0A8T0I7V1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_4G109100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7V1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070008">
        <property type="term" value="F:serine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.980:FF:000005">
        <property type="entry name" value="Clan SC, family S28, unassigned serine peptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.980">
        <property type="entry name" value="Serine carboxypeptidase S28, SKS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008758">
        <property type="entry name" value="Peptidase_S28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042269">
        <property type="entry name" value="Ser_carbopepase_S28_SKS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010">
        <property type="entry name" value="PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11010:SF11">
        <property type="entry name" value="THYMUS-SPECIFIC SERINE PROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05577">
        <property type="entry name" value="Peptidase_S28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035890620" evidence="6">
        <location>
            <begin position="25"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0579592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="490" mass="54549" checksum="8900BF26ABF3380B" modified="2022-10-12" version="1">MAAMVPLLLRLVACLCFCFCGALAAPAFLRPPLTHSLSHSPDDYYVTKQPFWFSQRLDHFASQDRRAFPQRYYHFQSFFDRPHSGPIFLRICGEGTCSGISNDYLVVLAKQFGAAIVCLEHRYYGESSPFKELTTDNLKYLSSKQALFDLASFRNFYQDLVNKQFNRTTGEDNPWFVFGVSYPGALSAWFRLKFPHLVRGSLASSGVVLAVHNYTAFDEQVAASAGPACASALREVTRRVDIELASNPVKIKSLFGAEQLKNDGDFRYLLADAAAEAFQYGNPDILCLPLVAAHTPGQDVVDAYAEFVKTFFFGTFGASPQGYNQEYLKLTKSGPDSGDRQWWYQVCTEVAYFQVAPSKNSIRSPGVDEKYHLDLCANVFGNGTYPEVDITNLYYGGSGITATNIFFTNGSQDPWRHASKQKSSPGEPAIIMTCHNCGHGSDLRGCPQSPFQIQGDATKCAKPNEVHKARQQIAEFIHMLLHKGETTFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I9R2</accession>
    <name>A0A8T0I9R2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_4G083200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I9R2"/>
    <dbReference type="OrthoDB" id="97518at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.200">
        <property type="entry name" value="LURP1-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007612">
        <property type="entry name" value="LOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038595">
        <property type="entry name" value="LOR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025659">
        <property type="entry name" value="Tubby-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31087:SF85">
        <property type="entry name" value="PROTEIN LURP-ONE-RELATED 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04525">
        <property type="entry name" value="LOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54518">
        <property type="entry name" value="Tubby C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0579223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="23451" checksum="2F748E744DCD9029" modified="2022-10-12" version="1">MGFQSDFSLLDLEELHAPTQALAAVVRQRYCIPTAAQYRLENELMSKAWTITDANGEVVFRVRGKKVDWIKSKRELVDESGNTVVYMEEKPWTLKNVWKAFAPGESEPLFTLKSTNAFSFKPRVNIFLPSNTAQKQPDYTIEGGFLAKKCRIYFGEELVAEVTREASLKNIIITKSIFNATIYPGVDIAFIFSIIIIIDKIYVHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAG9</accession>
    <name>A0A8T0IAG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">MICOS complex subunit MIC10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_4G191400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion inner membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MICOS complex subunit Mic10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061617">
        <property type="term" value="C:MICOS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007512">
        <property type="entry name" value="Mic10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21304:SF0">
        <property type="entry name" value="MICOS COMPLEX SUBUNIT MIC10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04418">
        <property type="entry name" value="DUF543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0580684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="93" mass="10296" checksum="34C219E248EBDED9" modified="2022-10-12" version="1">MPDGPKNKDVAKPRRMTQMELEEQYDLVFDLTLRRCIYGSMSGLAAALLIFRSPTKRWSAVAFGAGIGVGSAYADASRILGDRMIAFPKWPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAH5</accession>
    <name>A0A8T0IAH5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G135400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAH5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36374">
        <property type="entry name" value="OS01G0969000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36374:SF1">
        <property type="entry name" value="OS01G0969000 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0579927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="146" mass="16579" checksum="5FF03CD6619CE515" modified="2022-10-12" version="1">MPNTVDEPIQVSGSCFGSWRGLKLWRKQCFGLCSGFTLVGTCKISQNSKVLVGFKRVMASVEETRVAEDGDEVQQKGPLIVRFPRQTAAVEPVKLESEEAEAESKPPRNMIQVYLLAGYLVGRWAWARFQERQSRRKFDGRRDPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAS2</accession>
    <name>A0A8T0IAS2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G199900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAS2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035817538" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="59" mass="7203" checksum="61189B8900969B06" modified="2022-10-12" version="1">MANPCLIQFYKSLVLLLYMWRSSYCRSFQHMSCETLKHYQINRVFYHENLLFNNAVFCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAT8</accession>
    <name>A0A8T0IAT8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G180100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAT8"/>
    <dbReference type="OrthoDB" id="40579at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07505">
        <property type="entry name" value="HAD_BPGM-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="entry name" value="Putative phosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051600">
        <property type="entry name" value="Beta-PGM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193">
        <property type="entry name" value="6-PHOSPHOGLUCONATE PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46193:SF19">
        <property type="entry name" value="HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN SGPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01135">
        <property type="entry name" value="C1.5.6:_HAD__Beta-PGM__Phospha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="188"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="491"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="503"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0580532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="512" mass="54551" checksum="BFAC6C1DDA3200FD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IBG9</accession>
    <name>A0A8T0IBG9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G160600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IBG9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.630.30:FF:000106">
        <property type="entry name" value="Acetyltransferase At1g77540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PROTEIN NATD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435:SF9">
        <property type="entry name" value="PROTEIN NATD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="32"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="128" mass="14038" checksum="F354B486DAAE17F5" modified="2022-10-12" version="1">MAASMQGRGVATGAREAAKVVWSPEQRRFASEDGLAYLAYNMRKPGKGMGEEGEEPAKEVMDVVHTYVPMQKRGLGLAGELCKAAFAHAREHKLLILPSCSYVSDTFIPRHPECWDVVVPESLHRAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDC7</accession>
    <name>A0A8T0IDC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_4G208600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDC7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="45"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="154"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0580896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="17836" checksum="82ADC0B847ADD357" modified="2022-10-12" version="1">MAFFGRLGGLMRQNAAQSVLVKSGLGVAAAAVPSLLMLQRGMSSSKLFIGGLAWGIDENTLRDAFGSFGSVTEVKIILDRDTGRSRGFGFVNFTSPQEAEVALQEMDGRELAGRQIRVDYATDKSVGAPRGGGGGGYGGNRGGYGDRQQGGGRFDNRGQDDGERGYGGNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDJ4</accession>
    <name>A0A8T0IDJ4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G183600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDJ4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="885" mass="93389" checksum="145A5B4BD0D589FE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IET4</accession>
    <name>A0A8T0IET4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Histone-lysine N-methyltransferase ATXR5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_3G016900</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IET4"/>
    <dbReference type="OrthoDB" id="336088at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006325">
        <property type="term" value="P:chromatin organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15543">
        <property type="entry name" value="PHD_RSF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10539">
        <property type="entry name" value="SET_ATXR5_6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053114">
        <property type="entry name" value="ATXR5/ATXR6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48442:SF1">
        <property type="entry name" value="SET DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0156">Chromatin regulator</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="98"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SET" evidence="7">
        <location>
            <begin position="280"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0581882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="414" mass="47700" checksum="2BC7603BCAF4EFB4" modified="2022-10-12" version="1">MERPRYGKERRAKRVRISTLYRTHCSQVVECQWNDYPSPSPCKNTVDFAEEVLPTSAVAEPPKVEEPKTYVKKKQRIVKDEQVKVGTEMVIWTDPALIYSCTMCEECGRGDSADQMLLCDKCDRGFHMFCLSPILVSIPPGDWICPHCSQSTTAYEFQMVQRKIVEYFRFKKFVPSKTVMEGIEKRTLKKQKSSSSQKRGLRLLPYVPTIDLQRRLEQMASLAAALTNIGLDFSDSLSYGYAPRTANRAANEKGGMREMSKEDKVTLDRCKAMCKRGEWQPLMVTYDLRQGFVVEADEDIPNMTFIAEYTGEVDYMCCRHYDSGNSIMGLLFSDDPVKELVICPDRRGNIARFLSGINNHTEEGRSKQNVRCVRYSINGEARVILIAMRDIRKGERLYYDYNAYYTEYPTQHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IG86</accession>
    <name>A0A8T0IG86_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G017300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0581887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IG86"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.606.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="PAP2/HPO_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052559">
        <property type="entry name" value="V-haloperoxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599">
        <property type="entry name" value="PEROXIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34599:SF1">
        <property type="entry name" value="PHOSPHATIDIC ACID PHOSPHATASE TYPE 2_HALOPEROXIDASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="Acid phosphatase/Vanadium-dependent haloperoxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="360" mass="40361" checksum="90437CB648B1634D" modified="2022-10-12" version="1">MKYTMAKHYEGRGLQIRATLVMTLMTLVLRPVVVTAAIDNVAFQWTNLLNSLFCPIRQSPFTSSIQPQLHLAQWHALLALRSTGDCTTEEAVVAYASHKILSHYYSASQDVVISPFLDRQLRAMKLTTRQKKLAKRLGEAVAVSLILKRSPANEFALGAVKDALNANPHPAVGVFRYFNDTPPDQTNFMFDNLGFEKPFIIPDMLKFVKDHLSDLKPMEIPSKEWDDNWKGLKDIGREDWPGRTPEINLIAALIACFRVNTTICSREQVATASAQSALPSATSLYDTVVLLAKISVSIYDAEAVHIVIKYGYWFWRPIHAYPAGDPQHKPIPTWKPYFPTPVEPEYPSGTVTAVSREACT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IHZ8</accession>
    <name>A0A8T0IHZ8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_3G041000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IHZ8"/>
    <dbReference type="OrthoDB" id="10376054at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004860">
        <property type="term" value="F:protein kinase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032875">
        <property type="term" value="P:regulation of DNA endoreduplication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040389">
        <property type="entry name" value="SMR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33142">
        <property type="entry name" value="CYCLIN-DEPENDENT PROTEIN KINASE INHIBITOR SMR13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33142:SF8">
        <property type="entry name" value="CYCLIN-DEPENDENT PROTEIN KINASE INHIBITOR SMR9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0649">Protein kinase inhibitor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="47"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="88"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="119"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0582188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="154" mass="16883" checksum="0A18C67084F08AD8" modified="2022-10-12" version="1">MAPTTAGCCPMLQTQSLEPMEVGSGRRRLSLDSWVCLPILRPVRTASSTSSQLSSSSGSSCTTQKTQDLPQAKPQTLTLDVTFTGEDEALTRESGCETPKSKEHRIPDVDVGFCPPAPRKPRAMARRRRVQPTSFFNTPDFENFLSQHKVQVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0INT4</accession>
    <name>A0A8T0INT4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G213300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0INT4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0584491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="207" mass="23623" checksum="FBFA76D57615A942" modified="2022-10-12" version="1">MGSKKNKLARAPASARRKLRLEINQRRKEEIEHQSELERLRVLRAAQKRKYHRAWRARTRKTRDEVTEQEDIGSGAGPAGDYSREEHNTSEHEVLKSPLRDQEVESAGNETSGGMSDEENILLTPGTDFTADEGEDSDRGRVTRARNRKCRIAAERGVSYLMQLLEAGFTDEEKKLVLHLFFADERIRALDPELSTTVLLMKVCKSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IPJ7</accession>
    <name>A0A8T0IPJ7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G259300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IPJ7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="70" mass="8043" checksum="DAE5C336F9D89AE1" modified="2022-10-12" version="1">MELGQFEQLRCGYSTKYGGSCNNYGKSLLNYILEGQATFWTWSTMLSYFDNQAEILCRSVRGCNKNTTHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRU8</accession>
    <name>A0A8T0IRU8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G036900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRU8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0585765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="56" mass="6013" checksum="FFA42D571B6C692E" modified="2022-10-12" version="1">MTRISIALPSALGPLQAVTSGESLIVAKWCLTRIFNAAKCTKTVVVCYSFTAPRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ISL5</accession>
    <name>A0A8T0ISL5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G111100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ISL5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="26"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0586710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="15048" checksum="619C6233C76BE130" modified="2022-10-12" version="1">MDQLEQPSGSAPVPPKSGKRKWTRQRDWEEAETSVLLQCVNSPRFQKKKRNQYCTKWEAIAQQIRTRENRVDSDSAINAKRCSHRMKTLNGYFNRCKKEKKVGWSEVEWRKANGIVVNWWYDAIAKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ITC7</accession>
    <name>A0A8T0ITC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Beta-adaptin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_2G058600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 11">Subunit of clathrin-associated adaptor protein complex that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10 11">Adaptor protein complexes are heterotetramers composed of two large adaptins (beta-type subunit and alpha-type or delta-type or epsilon-type or gamma-type subunit), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasmic vesicle</location>
            <location evidence="1">Clathrin-coated vesicle membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
            <location evidence="2">trans-Golgi network</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ITC7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030131">
        <property type="term" value="C:clathrin adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030665">
        <property type="term" value="C:clathrin-coated vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000002">
        <property type="entry name" value="AP complex subunit beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.310.10:FF:000012">
        <property type="entry name" value="Beta-adaptin-like protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.1150:FF:000002">
        <property type="entry name" value="Beta-adaptin-like protein C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026739">
        <property type="entry name" value="AP_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016342">
        <property type="entry name" value="AP_complex_bsu_1_2_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015151">
        <property type="entry name" value="B-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013037">
        <property type="entry name" value="Clathrin_b-adaptin_app_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11134">
        <property type="entry name" value="ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09066">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002291">
        <property type="entry name" value="AP_complex_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01020">
        <property type="entry name" value="B2-adapt-app_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0968">Cytoplasmic vesicle</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="13">
        <location>
            <begin position="668"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-adaptin appendage C-terminal subdomain" evidence="14">
        <location>
            <begin position="787"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="587"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="617"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00056315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00065056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR002291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0586036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="900" mass="99615" checksum="CB09DE3633B312F4" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXJ5</accession>
    <name>A0A8T0IXJ5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribulokinase/uridine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G189300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXJ5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10285">
        <property type="entry name" value="URIDINE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phosphoribulokinase/uridine kinase" evidence="2">
        <location>
            <begin position="161"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0587762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="40856" checksum="0D8DD3A3CB9884D7" modified="2022-10-12" version="1">MHGNRGYISHEQDHHPSCDSRSITKCKRRPPIMAATAHLAASSSLLLPRTKQPWMASSGWESSASLPTRAGVALASTGNKNTGTYVGAWNQLVPVDSRLCTKKRGIVERCGRQRANQQWHCSVQENPRVLQSSSMDETYDILANQLLSRALITETGQKYMVGIAGSPGAGKSTVAKEVAARLNVLWLEKQGEKSGDIEASPTEIAVAVPMDGFHLYRRQLDAMEDPVEAHARRGAHWTFDPASLVKNLQQLRSQGWAHLPSFDHGVGDPVEKDIYVSPMHRVVVVEGNYLLMEEGEWTGLADLFDERWYVDIDIDEAMKRVERRHVSTGKTPDYAKQRVVYNDRPNAELIALTKRNADLIIPSISVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXJ6</accession>
    <name>A0A8T0IXJ6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Auxin response factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_2G245400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimers and heterodimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ARF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009734">
        <property type="term" value="P:auxin-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.30.1040:FF:000001">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.330.10:FF:000001">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000047">
        <property type="entry name" value="Auxin response factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010525">
        <property type="entry name" value="ARF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044835">
        <property type="entry name" value="ARF_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033389">
        <property type="entry name" value="AUX/IAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053793">
        <property type="entry name" value="PB1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31384">
        <property type="entry name" value="AUXIN RESPONSE FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31384:SF115">
        <property type="entry name" value="AUXIN RESPONSE FACTOR 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06507">
        <property type="entry name" value="ARF_AD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02309">
        <property type="entry name" value="AUX_IAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54277">
        <property type="entry name" value="CAD &amp; PB1 domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51745">
        <property type="entry name" value="PB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0927">Auxin signaling pathway</keyword>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="10">
        <location>
            <begin position="137"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="PB1" evidence="11">
        <location>
            <begin position="748"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="463"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="603"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="848"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="475"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="625"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="848"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0588470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="885" mass="98294" checksum="50D5DBD4CDF96FB9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IYH3</accession>
    <name>A0A8T0IYH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein DA1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G231100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IYH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045218">
        <property type="entry name" value="DA1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022087">
        <property type="entry name" value="DA1-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24209">
        <property type="entry name" value="PROTEIN DA1-RELATED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24209:SF7">
        <property type="entry name" value="PROTEIN DA1-RELATED 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12315">
        <property type="entry name" value="DA1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein DA1-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="101" mass="11185" checksum="4783F841D3529A6D" modified="2022-10-12" version="1">MMVVVIVVAPVEAPAVMMIDQEVPMLLVARDALNEAREGEKEGMHTSETRGLCLSEEQTITTVFGGKSRGRNPFPSIWTEPHKLVRHCEVTAILVLYGLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IZT1</accession>
    <name>A0A8T0IZT1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Serine hydroxymethyltransferase</fullName>
            <ecNumber evidence="9">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_2G230000</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Interconversion of serine and glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="9"/>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IZT1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000050">
        <property type="entry name" value="Serine hydroxymethyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049943">
        <property type="entry name" value="Ser_HO-MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF000586">
        <property type="entry name" value="PRK00011.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680:SF28">
        <property type="entry name" value="SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Serine hydroxymethyltransferase-like" evidence="10">
        <location>
            <begin position="64"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000585"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0588266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="524" mass="57742" checksum="00A403BB71A69AC7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0X2</accession>
    <name>A0A8T0J0X2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Chlorophyll a-b binding protein, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_1G032400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 17">Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0X2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009522">
        <property type="term" value="C:photosystem I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016168">
        <property type="term" value="F:chlorophyll binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009765">
        <property type="term" value="P:photosynthesis, light harvesting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.3460.10:FF:000001">
        <property type="entry name" value="Chlorophyll a-b binding protein, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3460.10">
        <property type="entry name" value="Chlorophyll a/b binding protein domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001344">
        <property type="entry name" value="Chloro_AB-bd_pln"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022796">
        <property type="entry name" value="Chloroa_b-bind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21649">
        <property type="entry name" value="CHLOROPHYLL A/B BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00504">
        <property type="entry name" value="Chloroa_b-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103511">
        <property type="entry name" value="Chlorophyll a-b binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 16 17" id="KW-0148">Chlorophyll</keyword>
    <keyword evidence="4 17" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="12 17" id="KW-0157">Chromophore</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 17" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="9 17" id="KW-0603">Photosystem I</keyword>
    <keyword evidence="15 17" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="6 17" id="KW-0934">Plastid</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 17" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="binding site" evidence="16">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="16">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>chlorophyll b</name>
            <dbReference type="ChEBI" id="CHEBI:61721"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Mg</name>
            <dbReference type="ChEBI" id="CHEBI:25107"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>chlorophyll a</name>
            <dbReference type="ChEBI" id="CHEBI:58416"/>
            <label>6</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR601344-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU363080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0589590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="262" mass="27696" checksum="3902E1FAAFB83D55" modified="2022-10-12" version="1">MAAATAMHSTALAGQSLLKPVNELSRKVGAGEARVTMAKGSSGSIWYGADRPKWLGPFSGETPSYLNGEFAGDYGWDTAGLSSDPETFARNRELEVIHARWAMLGALGCVTPELLAMNGTKFGEAVWFKAGSQIFADGGLDYLGNPSLVHAQSILAIWACQVILMGAVEGYRVAGGPLGDVTDPIYPGGSFDPLGLADDPDTFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPLENLSDHLADPVANNAWAYATNFTPGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0X4</accession>
    <name>A0A8T0J0X4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1664 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G257300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0X4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012458">
        <property type="entry name" value="DUF1664"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46667:SF6">
        <property type="entry name" value="OS01G0185100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46667">
        <property type="entry name" value="OS05G0182700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07889">
        <property type="entry name" value="DUF1664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816861" description="DUF1664 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1664" evidence="2">
        <location>
            <begin position="96"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="358" mass="38354" checksum="6A32F91BE8D85B95" modified="2022-10-12" version="1">MAMQASLGATKFVILCSAGLAGSVLIKNNKLGDFIGDLSKVLSKHLREGDDGEAGSNDAALSQQVKRLAQELRMLASSSRTVTVVQAGNGSGVSFTTFVLPAAVVGAVGYGYMKWKGFSFSSIMYVTKKGLNTAVEQMGKQLDHVSAALSSTRKHMNQRLDTVNGKLDESIVMTGLIRDQVEEVKSTVGRSIYEIDNVSQKMGGLGLKIDEIQESQTFANQGIFLLVEWVHRQFPNQHPELAQSFKSWYLKASSMDKDSAFPGLITSPGLKQFFSQPLESQPSVPQPLLPPSNFCERAPVRNMGESRPPGLNMPSPGLGLSANASIGLPRTSSSSILSRVNMWGNSGLAGFTGTTGMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1A8</accession>
    <name>A0A8T0J1A8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G245700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1A8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0588473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="112" mass="12329" checksum="C7C91403A847039B" modified="2022-10-12" version="1">MKMTGAEAATTMAVAGSDSPSRSFGLKEKLGKLHLFTVDRTNRWPVQGWSSGDESHLELDEQFVAEESGRAFTVDKETRWPLQGWCQPHNSTQGAASVSSHPSAPSRWPQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J3F0</accession>
    <name>A0A8T0J3F0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7866 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G010400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J3F0"/>
    <dbReference type="OrthoDB" id="1871192at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057188">
        <property type="entry name" value="DUF7866"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33786">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33786:SF2">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25268">
        <property type="entry name" value="DUF7866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035750324" description="DUF7866 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="DUF7866" evidence="2">
        <location>
            <begin position="81"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF25268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="133" mass="14649" checksum="EC33C309AA27BDCE" modified="2022-10-12" version="1">MPVMGMGHNLQLVLLICTLAGASAILSWEDSQGFKELDEGDSMSLAGDMVRFSNGTELQLFPSAEAHVQEHINGTRRMLGVFRQCSPCTCCDKTRRWCLPTVCCYNIRCGLQGLPYGLCSFIPISCTCFGCRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J431</accession>
    <name>A0A8T0J431_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G087300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J431"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="56"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="190" mass="21281" checksum="362784A511A4F3BC" modified="2022-10-12" version="1">MGKEDASNAVLLVISQVGCDESGAGRLTMVVDGREMGSEEWRSLVAEAENFDVISVRVDRERLLEHSTYFRSLENFSELNRESLNVNWDPPIFCILLQCMHGFQSSFSSCVIARLIQAVDYFGVDEAITRCKNWVDSEMCNVRCGTEDDFLSDLLSIWSTATEIGLDLFQSSHELNICSLFDLTSLVASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4E5</accession>
    <name>A0A8T0J4E5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Stig1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G036000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the STIG1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4E5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006969">
        <property type="entry name" value="Stig-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33227:SF54">
        <property type="entry name" value="PROTEIN STIG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33227">
        <property type="entry name" value="STIGMA-SPECIFIC STIG1-LIKE PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04885">
        <property type="entry name" value="Stig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0589643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="217" mass="23928" checksum="784605B7DD6E8838" modified="2022-10-12" version="1">MTRQSHFLRHCSEWFPAAWKWLPTCRSTSKCTRDRAAAAEFLGSSSFLKSVKQLRLSMLFMFLAVVTFDFPIPLVAVSSSTSADPPALQMGSNSSSPVHGRFLQTSKRRAGRFSTGEETEPANARRLSGQYLCRWKKDICEQEPISYLLGPDCCNSVCTNMKTDAFNCGTCGQICFYGSICCNGVCTDIFSNNRNCGACDNICPSGEVCQYGLCGYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J510</accession>
    <name>A0A8T0J510_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G114700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J510"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001025">
        <property type="entry name" value="BAH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043151">
        <property type="entry name" value="BAH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46364">
        <property type="entry name" value="OS08G0421900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01426">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00628">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00439">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51038">
        <property type="entry name" value="BAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BAH" evidence="7">
        <location>
            <begin position="21"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="6">
        <location>
            <begin position="138"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0590625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="224" mass="25882" checksum="370863673CC302DB" modified="2022-10-12" version="1">MAKSKGVKKSLDSYTVKGTHKVVKVGDTVLMRQQDPEKPPYVAKIEKIEADAKNNAKVRVRWYYRPEESMGGRRQFHGSKELFLSDHYDIQSADTIEGKCIVHTFKNYTKLESVGAEDYFCRFEYKASTGGFTPDRVAVYCKCEMPYNPDDLMVQCEICKDWFHPSCMSFTPDQVKKMEKFICPDCTSQPGEKKVRQSSPRSSPTPDHVKVSNLSRRYFWFLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5V8</accession>
    <name>A0A8T0J5V8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_1G078100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5V8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043226">
        <property type="term" value="C:organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000178">
        <property type="entry name" value="Calmodulin-2 A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.238.10:FF:000089">
        <property type="entry name" value="calmodulin-like protein 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039647">
        <property type="entry name" value="EF_hand_pair_protein_CML-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10891">
        <property type="entry name" value="EF-HAND CALCIUM-BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="27"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="63"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="120"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="156"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0590173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="191" mass="21086" checksum="39C02D4EBB4C425F" modified="2022-10-12" version="1">MKLSLRKLGSRSSSRRMETVEVEPIAPLVKELTATFQVFDKDGDGRISKSELGVVLRSLGDDMSDDELDEVLVKVDGDGDGFIDLQEFISFHTGRASTAASRDDSVSRTLSESGDGVSSEEKYALQAAFEVFDVDRNGFISAEELQRIMRSLGEKTSLAECRHMINCVDKDGDNMVDFNEFQCLMSGTFVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J858</accession>
    <name>A0A8T0J858_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G223700</name>
        <name evidence="3" type="ORF">KC19_1G224400</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J858"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0592090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="140" mass="15999" checksum="9F080E55E1EDAF54" modified="2022-10-12" version="1">MRHTNQLESPPAQNRSPVDSQMRQVTSLSPESFVHYHREQLLLSVSLQTDCISKAKLNRSEWGQLRCPCSHGRSSASRNPYKNLRPRLPRMYTTSVPIHSLHLSVTIIKSSPSMLFHDHRSINILNRATRARHGDHTRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J867</accession>
    <name>A0A8T0J867_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Myb/SANT-like DNA-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G146400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J867"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044823">
        <property type="entry name" value="ASIL1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044822">
        <property type="entry name" value="Myb_DNA-bind_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31307:SF63">
        <property type="entry name" value="MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31307">
        <property type="entry name" value="TRIHELIX TRANSCRIPTION FACTOR ASIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13837">
        <property type="entry name" value="Myb_DNA-bind_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Myb/SANT-like DNA-binding" evidence="2">
        <location>
            <begin position="5"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="270" mass="31001" checksum="A448EA708243B004" modified="2022-10-12" version="1">MANVVWTKEDILALLEAYSDRYQQFNIGNFRPLDWDYVLLSVNAKKQPGMLGKTRQQVKNKMENMKKKYRQEKGAHTPGLPVKWSYFNDMDRIFGNNLRVLQTLDAENTAPVPKSIVKPEEGCSPSTPVIEVHLSVDLKESEELLPESTCLVDEEALPATSVQVENAPDIHSNSSARRGKKRRHNSYYSPAKALAGAITKFGELCTQLERDRAEREERRTEREERRQKENADREERILKMQMDMQLRLAELFTLGQKPNRGAPTGEEVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J8M9</accession>
    <name>A0A8T0J8M9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G167500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OST3/OST6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J8M9"/>
    <dbReference type="OrthoDB" id="67566at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008250">
        <property type="term" value="C:oligosaccharyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018279">
        <property type="term" value="P:protein N-linked glycosylation via asparagine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021149">
        <property type="entry name" value="OligosaccharylTrfase_OST3/OST6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692">
        <property type="entry name" value="DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12692:SF0">
        <property type="entry name" value="GH11935P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04756">
        <property type="entry name" value="OST3_OST6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035916302" description="Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3B" evidence="10">
        <location>
            <begin position="28"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="307"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0591329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="344" mass="38485" checksum="EA0F33F27E404B15" modified="2022-10-12" version="1">MGREERLGVMAVLVLVLVAVAIAGAGAESNEDRVADLMHMQAQAKDGVIRLDEHNFRRFMSTSEPRPYALILFFDASQLHSNTELRLVEFRKEFGLVATAYGKYHKGQESEGKVFFCDLEFKQMQGVFQLFKVQALPHVRFVAAGSGDQDASEEMNQGEFPRTAEGVASFVTAKTKQQCGPIERPPPLSKGQVWALATLVLLATPFAVRIAAAPDSPLREPRIWCFGALMIYFFSVSGGMHNIIRKMPLFMQDRNNPAKLVFFYQGSGMQLGAEGFVVGFLYTIVGLLLGFVTHFAPQIRSKIVQRLVMIVAITISFVAVRKVIALDNWKTGYWIHAFWPSRWT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J9M2</accession>
    <name>A0A8T0J9M2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G191200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J9M2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013744">
        <property type="entry name" value="SidJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31591:SF1">
        <property type="entry name" value="UPF0613 PROTEIN PB24D3.06C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08538">
        <property type="entry name" value="DUF1749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="315" mass="34555" checksum="CEA4D678CB04572D" modified="2022-10-12" version="1">MEDSSGPNRETAQHGQVSEGGAAMASSRKLPKLQGSLFKYGSKSIQVAFQSGNYKQHVIIIGGLTDGLFATDYVEPLAKALEAEKWSLVQPLFSSSYTGFGTSSLKEDALEIEQLLNYLIDQENSEGFILIGHSTGCQDIVNYLRTGGHCTRAVRGAILQAPVSDREFLVTLPETQPKLELAEKMIKEGKGEELMPRDTSPEAPITAYRFHSLSTVLGDDDLFSSDLSDAQLKARLGHMSRVPTQVLFSMSDEYVPDHVDKVTLIKRLCEAMGGAEKMAIPWGNHSLSNRVEEAVRTMISFIKKGGPKGWDDPWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JC08</accession>
    <name>A0A8T0JC08_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G330100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JC08"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035909812" evidence="1">
        <location>
            <begin position="18"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0593444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="63" mass="7369" checksum="52892948A0A2FCC4" modified="2022-10-12" version="1">MGLLHFLICIITKLAASCDVFKKIFRVVHYLILNVQPVQVRLSNATLYWQIGFNQLHEEMFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JCH8</accession>
    <name>A0A8T0JCH8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NADH dehydrogenase subunit 6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G250000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JCH8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035797014" description="NADH dehydrogenase subunit 6" evidence="2">
        <location>
            <begin position="22"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0592411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="84" mass="9558" checksum="96B4EC6C694AE342" modified="2022-10-12" version="1">MDMWIMLRTMFMLFCFELCFDEFAACGFIVVVELDTSCGVICSQGGFDWSGLGIFLVIGVYCAVQHCLRECCMQEERSLEWSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G287</accession>
    <name>A0A8T0G287_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G006300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G287"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035729671" description="Secreted protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="71" mass="7949" checksum="1C618CE54B4874E0" modified="2022-10-12" version="1">MVRSMVLVELGVLLPTLIAFCSACRMTMFDKSFFHRVLSAVSAGKCANPYLYPQYRSQDILASQILMQSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G5C5</accession>
    <name>A0A8T0G5C5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G028300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G5C5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12209" checksum="5A78E1896A350DF8" modified="2022-10-12" version="1" fragment="single">AQQSELLVQVEPAQNSSWRTRFCERFLKPQFYRQIPCPVHHVTRSASLKTRSNNETIPTATTRMDTPTLTPSWMDQSINHSINPSRRLQLAMLLQPLPGYSDDTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G665</accession>
    <name>A0A8T0G665_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G004100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0553348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G665"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035742051" evidence="1">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0553348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6466" checksum="585FDB69315BFCDB" modified="2022-10-12" version="1">MLWRICLQFTFSSIILHHFLQKSLCSTCFNQDFFKTAIILLGDFTVTIYSDLESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G797</accession>
    <name>A0A8T0G797_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Shikimate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G113300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G797"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001033">
        <property type="entry name" value="Shikimate kinase 2, chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087">
        <property type="entry name" value="SHIKIMATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087:SF16">
        <property type="entry name" value="SHIKIMATE KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0554715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="306" mass="33789" checksum="F8523E7F2702648F" modified="2022-10-12" version="1">MSLLHIDSQNKMAALGVASVSRSFVSLQETTPGPCHWGGYQRFRPSAARLTTFQRECSLNALRPWERRSLAKDKVVMAFSSQHNLSATDLSDDAVAEDLSPNYDLELMKKADEVRDDLHGTCIFLIGLLDSRKAFIGKTLAKELGYYFFDSNDLVQQAAGEAEISEGEEGYSEAETEVLKQLSAVGRLVVSTGAGTVAKSENWGFLRHGIVIWIDMPVETVAKDAKTRHLLVPNCADDEALAKMSKLYEERKETYRNADAMVSIQALSAQLGFKSPSEITPTMTALEVLNVIGVLIKEKQAKKVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7J9</accession>
    <name>A0A8T0G7J9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G055700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7J9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36896">
        <property type="entry name" value="OS01G0729500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36896:SF2">
        <property type="entry name" value="OS01G0729500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035914528" evidence="1">
        <location>
            <begin position="29"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="142" mass="15456" checksum="5521E4EC2F637C64" modified="2022-10-12" version="1">MAILGRRMLSIASVLVLVLVTWTHGAACEPDVCRRIAARGECMGEGDGGGGKGCVWCDVPQRCVSAAQVLEFGADSCFGRLRRQSRRLLDERNECGTIATKDLCSKVDYCKWCRSEVLDDTCFGAAESARLPRTIFLCSDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7N9</accession>
    <name>A0A8T0G7N9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LOB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G139300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOB domain-containing protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7N9"/>
    <dbReference type="OrthoDB" id="1893065at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004883">
        <property type="entry name" value="LOB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31301:SF21">
        <property type="entry name" value="LOB DOMAIN-CONTAINING PROTEIN 27-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31301">
        <property type="entry name" value="LOB DOMAIN-CONTAINING PROTEIN 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03195">
        <property type="entry name" value="LOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50891">
        <property type="entry name" value="LOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LOB" evidence="4">
        <location>
            <begin position="22"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="102"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0555040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="334" mass="36318" checksum="6C6FD087696A5E2D" modified="2022-10-12" version="1">MAGSGSGGSGSGSGGGGGGTSTACAACKYQRRKCTPDCPLSPYFPPDQPKRFQNVHKLFGVSNILRILKHVDPSKREDTVKSIAYEADTREKDPVHGCLGVITILQNQVSKLKDELAVAREQLYILQQQHNYNQQAQMQEIVGSLGGSTALVNVSSAQETNVLMQHLQQYNDMTQLSSDFAKSNPLPVSSFEPDQYLRNDTFDQIKPGSASTSRFDVGRYIRGESPVNHQPSPLLGPVKEEQAEHHRGASMHYGMGDSSTTFLESSADHNLLQDLDHAFDTPDPYAMAIRRPGSSGLLNLTVASEAELRRASGHHGVPEHELRSAGVYLTLTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G9K4</accession>
    <name>A0A8T0G9K4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Vacuolar protein sorting 26</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_11G009000</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Plays a role in vesicular protein sorting. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS29-VPS26-VPS35 subcomplex may be involved in recycling of specific cargos from endosome to the plasma membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Component of the retromer complex which consists of VPS29 (MAG1), VPS26 (VPS26A or VPS26B), VPS35 (VPS35A or VPS35B or VPS35C), VPS5/17 (SNX1 or SNX2A or SNX2B). Component of a retromer subcomplex consisting of VPS29 (MAG1), VPS26 (VPS26A or VPS26B), VPS35 (VPS35A or VPS35B or VPS35C).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Endosome membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Golgi apparatus</location>
            <location evidence="4">trans-Golgi network membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Prevacuolar compartment membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the VPS26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G9K4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010008">
        <property type="term" value="C:endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000006">
        <property type="entry name" value="Vacuolar protein sorting-associated protein 26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.640:FF:000012">
        <property type="entry name" value="vacuolar protein sorting-associated protein 26A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.640">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014752">
        <property type="entry name" value="Arrestin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028934">
        <property type="entry name" value="Vps26-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12233">
        <property type="entry name" value="VACUOLAR PROTEIN SORTING 26 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03643">
        <property type="entry name" value="Vps26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00056169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00064408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0555863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="298" mass="34699" checksum="233CEB0195438059" modified="2022-10-12" version="1">MNYLIGAFGPPCSISIDFADAETRKQASVKKENGQTVLVPLFLGNESVVGEVRIDPVPGKKVEHTGVKIELLGQIELYFDRGSFYDFTSLVRELDVPGEILERKTYPFEFSTVEMQYESYNGVNVRLRYILKVTISRSYATNIVEYKDFWVRNYSPHPEINNSIKMEVGIEDCLHIEFEYSKSKYHLKDVIVGKIYFLLVRIKIKHMELEIRRRESTGSGPNTYNESETLAKYEIMDGAPVRGESIPIRLFLSPYDLTPTYRNINNKFSVKYYLNLVLVDEEDRRYFKQQEITIYRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAG1</accession>
    <name>A0A8T0GAG1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">C-terminal of Roc (COR) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G045500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47679:SF1">
        <property type="entry name" value="PROTEIN TORNADO 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1350" mass="153064" checksum="7BD8765A948544C2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAJ6</accession>
    <name>A0A8T0GAJ6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G000300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAJ6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035897652" evidence="1">
        <location>
            <begin position="17"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="83" mass="9701" checksum="8ECFFE7DB70231BE" modified="2022-10-12" version="1">MQSGFLILLVAIYTCSDWLMDLRNRRKAYAREIAARQAHEHISEHERLKQVNNIAKRQASKLTRKLTRTLSRKQLVPSLGEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAY6</accession>
    <name>A0A8T0GAY6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aminotransferase class I/classII large domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_11G036800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAY6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004838">
        <property type="term" value="F:L-tyrosine-2-oxoglutarate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:L-tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00609">
        <property type="entry name" value="AAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.640.10:FF:000048">
        <property type="entry name" value="tyrosine aminotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II_large"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005958">
        <property type="entry name" value="TyrNic_aminoTrfase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01265">
        <property type="entry name" value="tyr_nico_aTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45744:SF2">
        <property type="entry name" value="TYROSINE AMINOTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000517">
        <property type="entry name" value="Tyr_transaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotransferase class I/classII large" evidence="8">
        <location>
            <begin position="88"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000517-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0556230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="472" mass="51713" checksum="E71D9C89196C6E47" modified="2022-10-12" version="1">MVTFVSHKAIQENGNALVLPLPEKKVPQSQLVNGDQVHKFPLTTEVLSEEAKLDAEWNVQACPAAIESTNPIRELLESLCVVSSKKKEKISLAQGDPTAFGHLKVPDAAVEAMVAATKSYMCNGYTHSAGSYECRKAVADYHSSSLPLKLTADDIGITVGCSQAIQLCIAALATPGSNMLIPRPGFPIYETFCKYYGVACRFYDLLPERDWEVDLDQIVSLADSNTVAWIVCNPSNPCGSVYKYQHLRKIANTAEKLKVPLISDEIYANMVFGATEFTPMAAFSMEVPVLTVGGISKRWLAPGWRLGWIIIADPKGILSRGKVVEALTRLMQMTIGTSTLSQAAVSGMLLNTPSSFFENTINSLKAGAEFCFERVQHIKGLYCLTKPQGAMYIMVRIDPAVFTDIRSDVEFASLLVEEESVVVLPGTAFGTPNWLRIVFATPLPQLEEAWDRIDLFCLHHSAAIPHSGTQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GDM2</accession>
    <name>A0A8T0GDM2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dihydropyrimidine dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="2">1.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_12G159800</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; beta-alanine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.2" evidence="2"/>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GDM2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017113">
        <property type="term" value="F:dihydropyrimidine dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002058">
        <property type="term" value="F:uracil binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02940">
        <property type="entry name" value="DHPD_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000121">
        <property type="entry name" value="Dihydropyrimidine dehydrogenase (NADP(+)), chloroplastic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006183">
        <property type="entry name" value="PRK08318.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073:SF2">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="53"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0555312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="428" mass="46661" checksum="386776A3F244E972" modified="2022-10-12" version="1">MAGLTHSLRLSALDQAVTASGELFKQSRQHDQRCRLPRSQRVMVRAALEGPDLSVVVNGLKLPNPFVIGSGPPGTNYTVMKRAFDEGWGGVIAKTVSLDSSKVVNVTPRYARLKASAVAGTKAEVIGWQNIELISDRPFETMLAEMKQLKEEYPDRILIASIMEEYNRDAWEEIIERVEETGVDAFEINFSCPHGMPERKMGMAMGQDCSVLGEVCGWINAKATIPVWAKMTPNITDITQPARTALNAGCEGVAAINTITSVMGINLDTLRPEPCVEGYSTPGGYSSKAVRPIALAKVMSIAQMMKAEFPGQDKSLSGIGGVETGNHAAEFILLGASTVQVCTGVMLHGYGHVKHLCTELQAFMDKHGFTSIEDFRGASLEYFTTHADLVQRQKEATENKKKVRKGLASDKDWTGEGFVKETETMVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GE87</accession>
    <name>A0A8T0GE87_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CYRIA/CYRIB Rac1 binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G069300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030833">
        <property type="term" value="P:regulation of actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009828">
        <property type="entry name" value="CYRIA/CYRIB_Rac1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008081">
        <property type="entry name" value="Cytoplasmic_FMR1-int"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12195">
        <property type="entry name" value="CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07159">
        <property type="entry name" value="CYRIA-B_Rac1-bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05994">
        <property type="entry name" value="FragX_IP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008153">
        <property type="entry name" value="FMR1_interacting"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01698">
        <property type="entry name" value="CYTOFMRPINTP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYRIA/CYRIB Rac1 binding" evidence="1">
        <location>
            <begin position="157"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1302" mass="148251" checksum="2AF3E59F8C8126E8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GG50</accession>
    <name>A0A8T0GG50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_11G171000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GG50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035266">
        <property type="term" value="P:meristem growth"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010073">
        <property type="term" value="P:meristem maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044622">
        <property type="entry name" value="PCN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45086">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN PCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45086:SF1">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN PCN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="194"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="472"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0557990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="900" mass="95847" checksum="B6C5D06E571C4BEA" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIB9</accession>
    <name>A0A8T0GIB9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_10G017100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIB9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0558297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="96" mass="10309" checksum="4DA1FDC7396B682D" modified="2022-10-12" version="1" fragment="single">QSIHQTNTPAPTYATFKTLACILPHLREDFGERLLLVCLSRPAQTVRNKCLGVPHLSLLPSLPSTYNNFFLLSRYAQAQAQTHSGGGGGAGSGSQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GIN7</accession>
    <name>A0A8T0GIN7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_10G059600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GIN7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01417">
        <property type="entry name" value="Ribosomal_L19e_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1200.240:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1650.10:FF:000001">
        <property type="entry name" value="Ribosomal protein L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_eL19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_eL19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="Ribosomal_eL19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023638">
        <property type="entry name" value="Ribosomal_eL19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_eL19_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_eL19_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033935">
        <property type="entry name" value="Ribosomal_eL19_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057259">
        <property type="entry name" value="Ribosomal_L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057260">
        <property type="entry name" value="Ribosomal_L19e_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006343">
        <property type="entry name" value="PRK08570.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25476">
        <property type="entry name" value="Ribosomal_L19e_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="Ribosomal protein L19 (L19e)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00526">
        <property type="entry name" value="RIBOSOMAL_L19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Large ribosomal subunit protein eL19" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="144"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="144"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="186"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0558860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="206" mass="24054" checksum="52545E116F2A8C50" modified="2022-10-12" version="1">MVSLKLQKRLAASVLKCGERKVWLDPNEVTEISMANSRQNVRKLVKDGFVIRKPQKIHSRARARRALEAKQKGRHSGYGKRRGTREARLPTKVLWLRRMRVLRRLLRKYRDAKKIDNHMYHDMYMKVKGNVFKNKRVLMESIHKSKAEKAREKTLSDQFEARRAKNKAIRERKLARREERQAQGIPEATAPAPAPASDAPVKKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJM7</accession>
    <name>A0A8T0GJM7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LOV domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G028800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJM7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009637">
        <property type="term" value="P:response to blue light"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000080">
        <property type="entry name" value="protein TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.450.20:FF:000153">
        <property type="entry name" value="Protein TWIN LOV 1 isoform D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47429:SF2">
        <property type="entry name" value="PROTEIN TWIN LOV 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="73"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="120"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="292"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="339"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0558444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="428" mass="46653" checksum="A140B270F6E29E9D" modified="2022-10-12" version="1">MSLGSTSSGVPEKLKMDGGSGGRSGSFGKRRPAKLEELVESLSRAYNEKIGHALGQHEYNFVLSDPRLPDHPIVFASEGFLRMSGYERDEVLGRNCRFLQGPDTDRGTVVEIRDAIREERACQVRILNYTKQGAPFWNLFHMAPIFASDGRVIHYVGVQTPIAPDLASQAVPVELPAEGVVEDGAVSSELEDQTPVEMRLNGGGEAKVDEEDDAEPAMVNEDLKKKAALAVQRVTGELTQSCRVEGAVLQNRRVGLSDCAANGVVSSSLMLSLTRIQQSLVLADPSLPDTPIVHASDVFCELTGYSREEVVGRNCRFLQGPDTDPEAVREIREAIQAEKPCTVRILNYRKDNTPFWNHLHVAPVRSATGKVAYYVGVQLDVSDADIPMRGDTMSANAKQLSAVGVVRVAVRSLQGSGLRRSFKTPQPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJX8</accession>
    <name>A0A8T0GJX8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PSII 6.1 kDa protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_11G126900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast thylakoid membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the psbW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJX8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009523">
        <property type="term" value="C:photosystem II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015979">
        <property type="term" value="P:photosynthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042549">
        <property type="term" value="P:photosystem II stabilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009806">
        <property type="entry name" value="PSII_PsbW_class2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34552:SF1">
        <property type="entry name" value="PHOTOSYSTEM II REACTION CENTER W PROTEIN, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07123">
        <property type="entry name" value="PsbW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0602">Photosynthesis</keyword>
    <keyword evidence="8" id="KW-0604">Photosystem II</keyword>
    <keyword evidence="5" id="KW-0934">Plastid</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0793">Thylakoid</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0557402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="136" mass="14023" checksum="B8B06971DADFEBF4" modified="2022-10-12" version="1">MAATSCATMAATSLATRSLATSSSFRTAAKPVAGLPALRMSRIVCSAEKKESKVEQVNGLPQLAAAVTSAASMAYAHPVFALVDERLSGEGTGLGLGVSNPRLTWIIVGVTALVWALYFTYSSNLPEGDDDSGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKE6</accession>
    <name>A0A8T0GKE6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NADP-dependent oxidoreductase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G044300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKE6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd19093">
        <property type="entry name" value="AKR_AtPLR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="entry name" value="NADP-dependent oxidoreductase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050523">
        <property type="entry name" value="AKR_Detox_Biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NAD(P)_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364:SF4">
        <property type="entry name" value="NAD(P)-LINKED OXIDOREDUCTASE SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43364">
        <property type="entry name" value="NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="NAD(P)-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADP-dependent oxidoreductase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="369" mass="39910" checksum="22973A05A4CF0247" modified="2022-10-12" version="1">MCACVGPALRFNHAGSYFGTLLPPNVGSLNSSSRTRVACSAKLNTNLDSSTEVMKLGRSDLQVSRLGIGTLQWGDPGSGFGTTFGEAELASAFDEIVAGGINFFDTAEVYGYQNIKSGSSSEQLLGKFLREKNQGGKGLPPVIATKFFTIPWTNFLVGGGFRLGRKSLLAALRESLKRIGKERVDLYQIHFPFPTFSNAALMESLKEAVEEGLTRAVGVSNFSKEQMEEADDLLSQYGIPLTSNQVQYSLASQDVEENGLLKACQDRNIQLIAYSPLASGLLTDKALTRTDGKATKIQPLLKLMQSIGREHGDKSVTQVALNYLICKGALPIAGCKNAQQAKAHCEVLKFKLTDDQVASLQEKARTLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKJ9</accession>
    <name>A0A8T0GKJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cyclin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G111500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclin family. Cyclin D subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKJ9"/>
    <dbReference type="OrthoDB" id="5590282at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd20543">
        <property type="entry name" value="CYCLIN_AtCycD-like_rpt1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd20544">
        <property type="entry name" value="CYCLIN_AtCycD-like_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000034">
        <property type="entry name" value="D2/4-type cyclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039361">
        <property type="entry name" value="Cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006671">
        <property type="entry name" value="Cyclin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10177">
        <property type="entry name" value="CYCLINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02984">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00134">
        <property type="entry name" value="Cyclin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 5" id="KW-0195">Cyclin</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin-like" evidence="6">
        <location>
            <begin position="85"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin C-terminal" evidence="7">
        <location>
            <begin position="182"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="40082" checksum="6B9F412D7C0B5640" modified="2022-10-12" version="1">MAFAESLYCSEEAWEDEEEVVSGSGSGSSVVVELQPVVFLDFPVEDDEAIATLLLKEGDYMPEDDYSGRYGARELSAGARLEAVEWIQKVQSFYNYGPLTVALAVNYMDRFLSRHHLPQGRDWMLQLLSVACISLAAKMEESEVPILLDLQVEQVEHVFEAHTIQRMELLVLSTLEWRMSVVTPFSYIDYFFHKLGISNVLLRALLTRVGDIVLKAVKDTIFLPYLPSVVAAAAIICSLEEVTALQSGDLMRIFGSLSVDVDAVKECYDDMQEVVMDSCYRRLSVKRKALLASEPQSPVGVLEAAALSSASEGTSGFSSRESSPGVCDVFPVATSSQSKRRKLLADDEQQSTTTWLQHTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GLM5</accession>
    <name>A0A8T0GLM5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G106200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GLM5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005096">
        <property type="term" value="F:GTPase activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00159">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.555.10">
        <property type="entry name" value="Rho GTPase activation protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025757">
        <property type="entry name" value="MIP1_Leuzipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052799">
        <property type="entry name" value="Rho_GAP_Regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008936">
        <property type="entry name" value="Rho_GTPase_activation_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000198">
        <property type="entry name" value="RhoGAP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46265">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46265:SF2">
        <property type="entry name" value="RHO GTPASE-ACTIVATING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14389">
        <property type="entry name" value="Lzipper-MIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00169">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00620">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00324">
        <property type="entry name" value="RhoGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48350">
        <property type="entry name" value="GTPase activation domain, GAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50238">
        <property type="entry name" value="RHOGAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0343">GTPase activation</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PH" evidence="4">
        <location>
            <begin position="25"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="Rho-GAP" evidence="5">
        <location>
            <begin position="176"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="386"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="516"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="780"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="614"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="397"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="534"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="780"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="936" mass="102255" checksum="FE2BFC7487A41002" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GM98</accession>
    <name>A0A8T0GM98_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PMS1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G121200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GM98"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032389">
        <property type="term" value="C:MutLalpha complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16926">
        <property type="entry name" value="HATPase_MutL-MLH-PMS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03484">
        <property type="entry name" value="MutL_Trans_hPMS_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000054">
        <property type="entry name" value="DNA mismatch repair protein PMS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1370.100:FF:000001">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000014">
        <property type="entry name" value="Mismatch repair endonuclease pms1, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="entry name" value="MutL, C-terminal domain, dimerisation subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="entry name" value="MutL, C-terminal domain, regulatory subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="MutL/Mlh/PMS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073:SF52">
        <property type="entry name" value="MISMATCH REPAIR ENDONUCLEASE PMS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="DNA mismatch repair protein MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA mismatch repair protein S5" evidence="5">
        <location>
            <begin position="236"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="MutL C-terminal dimerisation" evidence="4">
        <location>
            <begin position="725"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="367"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="392"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="413"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="928" mass="101344" checksum="2346807093734259" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GPA3</accession>
    <name>A0A8T0GPA3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G153900</name>
        <name evidence="3" type="ORF">KC19_10G154000</name>
        <name evidence="4" type="ORF">KC19_10G154300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GPA3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0560096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0560099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="170" mass="18702" checksum="632A762642DBB855" modified="2022-10-12" version="1">MPVDIVLLIHILEHGYIHLTVTDDDFDRILLLRVGNFDGGVLAKASGRGRPGGREMEWLVANSPRSLSRTLNIYFCGRTLMSPLWRGNILCPAVLMLAGEHGSFVIAFVTATWISVSGLHTGVRRWYCPEPGGGGWWVGGGVVCAMGWVCLFAVDTACVHVVWCWRVCCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS14</accession>
    <name>A0A8T0GS14_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="5">6.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G039800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>acetate + ATP + CoA = acetyl-CoA + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23176"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the ATP-dependent AMP-binding enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="5"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS14"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05966">
        <property type="entry name" value="ACS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.30:FF:000004">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12780:FF:000001">
        <property type="entry name" value="Acetyl-coenzyme A synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001208">
        <property type="entry name" value="PRK00174.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24095:SF14">
        <property type="entry name" value="ACETYL-COENZYME A SYNTHETASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyl-coenzyme A synthetase N-terminal" evidence="8">
        <location>
            <begin position="104"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="6">
        <location>
            <begin position="175"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding enzyme C-terminal" evidence="7">
        <location>
            <begin position="624"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0561129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="740" mass="81804" checksum="B2B4AE69CFF29CE9" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GTG8</accession>
    <name>A0A8T0GTG8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_9G135200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the amidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GTG8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="2">
        <location>
            <begin position="61"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0562300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="465" mass="49480" checksum="7B68276D4D483E97" modified="2022-10-12" version="1">MSETVVGAGEDGSMPVEAKDLEGDEVQHGTGARGKTSPPIENGFGAFISCFTLLPPSSLEHQYASLAGLTFAVKDIFDVDGHVAGFGSPDWARTQKPAKRTAPVIQALLNAGATCIGKVHMDEMAYSILGQNAHYGTPVNPINPARIPGGSSSGSGVAVAAKLVDFSLGTDTGGSVRAPAACCGILGFRPSHGAVSAVGVTPMAQSLDTVGWFARDVAILCKVGQLLLHTESPQDLRSAKRFIIADDCFNMSIHANDKRLGIIYKSVTSLHGGEALQHVNLGQYIESEVYSLKEFREKMGENNAFGTLGSLDDVLSHILRWEFKMNYEEWVTTEKPNLGDDTAFRVKKALNTTSHMMTLALRVKEETRHAINELLKGDAILVMPTVPEPPPMLNAEGEALDRYRASAFALLSVSVLSSCCQVSIPTGLVDSGPVAVSLLAKQGSDHFLLHTTSGLYTTIQKATNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUJ9</accession>
    <name>A0A8T0GUJ9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Pre-mRNA-processing factor 19</fullName>
            <ecNumber evidence="18">2.3.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_8G024000</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="24 25">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 18">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="16">Homotetramer. Component of the multiprotein assembly MOS4-associated complex (MAC) at least composed of MOS4, CDC5, PRL1 and PRP19 which is related to the PRP19C/Prp19 complex/NTC/Nineteen complex identified in other organisms. Associated with the spliceosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 18">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 18">Belongs to the WD repeat PRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.27" evidence="18"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000974">
        <property type="term" value="C:Prp19 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071006">
        <property type="term" value="C:U2-type catalytic step 1 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045087">
        <property type="term" value="P:innate immune response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070534">
        <property type="term" value="P:protein K63-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16656">
        <property type="entry name" value="RING-Ubox_PRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.130.10.10:FF:000043">
        <property type="entry name" value="pre-mRNA-processing factor 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000027">
        <property type="entry name" value="Pre-mRNA-processing factor 19, putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038959">
        <property type="entry name" value="Prp19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013915">
        <property type="entry name" value="Prp19_cc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055340">
        <property type="entry name" value="RING-Ubox_PRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43995:SF1">
        <property type="entry name" value="PRE-MRNA-PROCESSING FACTOR 19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08606">
        <property type="entry name" value="Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24814">
        <property type="entry name" value="WD40_Prp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="19" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10 18" id="KW-0227">DNA damage</keyword>
    <keyword evidence="14 18" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0391">Immunity</keyword>
    <keyword evidence="5" id="KW-0399">Innate immunity</keyword>
    <keyword evidence="6 18" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="13 18" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="15 18" id="KW-0539">Nucleus</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="8 18" id="KW-0747">Spliceosome</keyword>
    <keyword evidence="7 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="11 18" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="4 17" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="U-box" evidence="21">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="263"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="308"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="394"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="17">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="140"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="19">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00065458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU367101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0563356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="56842" checksum="0C73F496E86AB0DE" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GV98</accession>
    <name>A0A8T0GV98_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G044900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GV98"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0563606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="129" mass="14794" checksum="F48793CACE2B9D3D" modified="2022-10-12" version="1">MCEEMISRCSIGLGYCIVLVTLNCFTRCGHFLREVDMLLRCCAQRMCWIHVNGIAASFGWAEELLAGEFYLAHAPLLGQFFTCHRLHANFFVVTKHSKVCEETRGQKIVLVVGVFFCFLASLRYRVWCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GX04</accession>
    <name>A0A8T0GX04_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G092800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GX04"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050817">
        <property type="entry name" value="DjlA_DnaK_co-chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24074">
        <property type="entry name" value="CO-CHAPERONE PROTEIN DJLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="75"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="180" mass="19917" checksum="7D2C30048628468E" modified="2022-10-12" version="1">MRKLLRGGQVSITRAFVDNNVERVILQSSLHADAVSHSVSSSSPPKPFKLEERFRKVGRAGASIRASNEVGNYREHFATLGLCAAASKQDIKQAYRKLALQYHPDVCKGEHCDVMFKQVNNAYEGALDAEEQGIADVGDDLLDGFMGATDDSWEDWEEWMGWEGAGVSDYSSHVNPAYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GXD6</accession>
    <name>A0A8T0GXD6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G012900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0563217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GXD6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0563217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="127" mass="13966" checksum="91BB099B985683DC" modified="2022-10-12" version="1">MKLVAMCLTDLAVGKKGTKHLWCGAQSQTCELRDLIERPSRNSLLVCPGDAADLSTLVMAHCLYTATSLWHIFCKSNRQSPNLLTFARPNYLVMSDKIEVSGFLSFAACLRSLLMGHIAVPLALILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H1Y7</accession>
    <name>A0A8T0H1Y7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_7G039800</name>
        <name evidence="12" type="ORF">KC19_7G039900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TALE/BELL homeobox family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H1Y7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.60:FF:000117">
        <property type="entry name" value="BEL1-like homeodomain protein 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008422">
        <property type="entry name" value="KN_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006563">
        <property type="entry name" value="POX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050224">
        <property type="entry name" value="TALE_homeobox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11850">
        <property type="entry name" value="HOMEOBOX PROTEIN TRANSCRIPTION FACTORS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05920">
        <property type="entry name" value="Homeobox_KN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07526">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00574">
        <property type="entry name" value="POX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8" id="KW-0371">Homeobox</keyword>
    <keyword evidence="7 8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Homeobox" evidence="10">
        <location>
            <begin position="652"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="8">
        <location>
            <begin position="654"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="723"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="935"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="14"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="723"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="780"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0566119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0566121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="965" mass="102927" checksum="A81C85D65C506998" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H242</accession>
    <name>A0A8T0H242_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_8G140900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H242"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004309">
        <property type="term" value="F:exopolyphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1640.10">
        <property type="entry name" value="inorganic pyrophosphatase (n-terminal core)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112">
        <property type="entry name" value="BNIP - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12112:SF39">
        <property type="entry name" value="EG:152A3.5 PROTEIN (FBGN0003116_PN PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="DHH phosphoesterases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="116"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="367"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="601"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="660"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1206"/>
            <end position="1232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="183"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="373"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="383"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="486"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="503"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="618"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="632"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="707"/>
            <end position="719"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1125"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1209"/>
            <end position="1224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0564795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1245" mass="135499" checksum="CF24AB4A9CF6B5AD" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3E2</accession>
    <name>A0A8T0H3E2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_7G017100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0565830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3E2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37886">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37886:SF1">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="351" mass="39375" checksum="F401B677CE630836" modified="2022-10-12" version="1">MSMSQLMALLGSWGDGVCNMLSSKYSKLLLAGLVCPLLLLLLLIPLSRMSMLPLSTSGWRRCACELCESKGMGVEVHAEVRGVPSPSDVEWVHRQVQPLKRLVAGGGGAWVAPRKGINPRTRQQQLVDLRRFHGISHYENGSRSGVECPGELLVEHHHSYYGEPWAGGRDVFEFLATAMSLQPRHRVLEIGCGTLRVGLHFIRFLHASNFFCLERDALSLAAALLYELPANGLLNKRPLLLLGDDLQDASELLHGPPFDLVYASAVFLHMPDATVWKTVSVLAKRLADPHGRLFVSHNIKFCTRLSWTECESRLRKSGLQYVGKQTHDSLLFNHFEVWYEFKRHMDTNLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H817</accession>
    <name>A0A8T0H817_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_7G061000</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H817"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034085">
        <property type="term" value="P:establishment of sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18788">
        <property type="entry name" value="SF2_C_XPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002532">
        <property type="entry name" value="DEAD/H-box helicase 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="RAD3-like_helicase_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013020">
        <property type="entry name" value="Rad3/Chl1-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00604">
        <property type="entry name" value="rad3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472:SF41">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE DDX11-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="5"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="167"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="68"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="188"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0566399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="904" mass="100167" checksum="BF054B61DD0B1CC0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H876</accession>
    <name>A0A8T0H876_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="1">5.6.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_7G093900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="5.6.2.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.3" evidence="1"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18809">
        <property type="entry name" value="SF1_C_RecD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025476">
        <property type="entry name" value="Helitron_helicase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049163">
        <property type="entry name" value="Pif1-like_2B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10492:SF57">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14214">
        <property type="entry name" value="Helitron_like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21530">
        <property type="entry name" value="Pif1_2B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helitron helicase-like" evidence="3">
        <location>
            <begin position="284"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like DEAD-box helicase" evidence="2">
        <location>
            <begin position="888"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="domain" description="DNA helicase Pif1-like 2B" evidence="4">
        <location>
            <begin position="1191"/>
            <end position="1237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF21530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0566867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1352" mass="155778" checksum="9DEDB31B3830A191" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9H8</accession>
    <name>A0A8T0H9H8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">E2 ubiquitin-conjugating enzyme</fullName>
            <ecNumber evidence="1">2.3.2.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G091700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.23" evidence="1"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9H8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061631">
        <property type="term" value="F:ubiquitin conjugating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd23837">
        <property type="entry name" value="UBCc_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.110.10:FF:000028">
        <property type="entry name" value="Probable ubiquitin-conjugating enzyme E2 23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.110.10">
        <property type="entry name" value="Ubiquitin Conjugating Enzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000608">
        <property type="entry name" value="UBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057733">
        <property type="entry name" value="UBE2O-like_SH3-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057734">
        <property type="entry name" value="UBE2O-like_SH3-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016135">
        <property type="entry name" value="UBQ-conjugating_enzyme/RWD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46116:SF15">
        <property type="entry name" value="(E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23043">
        <property type="entry name" value="SH3-B_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23044">
        <property type="entry name" value="SH3-C_UBE2O"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00179">
        <property type="entry name" value="UQ_con"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00212">
        <property type="entry name" value="UBCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54495">
        <property type="entry name" value="UBC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50127">
        <property type="entry name" value="UBC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="UBC core" evidence="7">
        <location>
            <begin position="454"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="8">
        <location>
            <position position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="698" mass="79612" checksum="9EBEAE93EBC1D2B9" modified="2022-10-12" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H9N1</accession>
    <name>A0A8T0H9N1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Transcription initiation factor TFIID subunit 15b</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">KC19_7G187900</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TAF15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0568123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H9N1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12280">
        <property type="entry name" value="RRM_FET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="4.10.1060.10:FF:000008">
        <property type="entry name" value="TATA-binding protein-associated factor 2N isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999:SF7">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 15B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12999">
        <property type="entry name" value="ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="Zn_ribbon_RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="13">
        <location>
            <begin position="145"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="12">
        <location>
            <begin position="267"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="174"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="355"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="178"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="367"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00058775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00061442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG0568123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="16">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="395" mass="40171" checksum="377449A24A22424D" modified="2022-10-12" version="1">MPAPSPLPHKCCLSLSLSLSRGREGLRSGSWHGRADRAGKGKELNLRIVRASLHTWERFAMSGYGGGGGAGRYRDGGSAGGAVDRGGSRGGFRDGGGGGRGGYGRGGYGGGGGGYGGGGGGYGGGGYDRGGSRGGGGGGAGGGDRSGDWTCPNLSCGNVNFARRMECNKCSAPKPPTAGGGGGGGGYGGEQGSGGYGGRQGGGNSYDEPTQGGYGGRGNDRDHGRAYDSRGGGGGYGAQSRDDAGEQAVEEAVKQCDEHCDDHCDNARIYISGLPLDVKEDELRELFGGIGQVARIKQKRGYKDQWPYNIKIYQDESGKNKGDAVLSYEDPMAAHSAGGFFNDYEMRGHKIKVAMAAKSAPKPPPQGGGGGYRGGHRGGGGPDRRDGGGYRSRPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HBB6</accession>
    <name>A0A8T0HBB6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G153800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HBB6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090158">
        <property type="term" value="P:endoplasmic reticulum membrane organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061817">
        <property type="term" value="P:endoplasmic reticulum-plasma membrane tethering"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000535">
        <property type="entry name" value="MSP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008962">
        <property type="entry name" value="PapD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016763">
        <property type="entry name" value="VAP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809">
        <property type="entry name" value="VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10809:SF58">
        <property type="entry name" value="VESICLE-ASSOCIATED PROTEIN 4-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00635">
        <property type="entry name" value="Motile_Sperm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49354">
        <property type="entry name" value="PapD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50202">
        <property type="entry name" value="MSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MSP" evidence="2">
        <location>
            <begin position="92"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0567678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="317" mass="35688" checksum="420FE944CA062355" modified="2022-10-12" version="1">MAPSEKGGGGQGGQQQQQSWKLRMLWEKKAPVEVRPTSAYAQTVRKRPVYEHPFLQETLMREEAEYAAAAAATVNTSSSLAAWKALLLTRRRLQLDPAKHLYFLYDPGKQVSSAIQIKNVSRTHVAFKFQTTNPRSCFMRPNGGVLAPNESIIAIVVKFVEPIPGGQERKAKEKFKIVSLAVKPDTDYAPELFDQLKDIVSLERILRVVFIDPNKASPEQVNRLQRRLAEAEAAEAARMKPEKEGIPKNGMVEKGLVIDEWASAGLQIGGIPEETTQRTLSRSATGRRRRVFMRLRVVKVRLPNRSQYSKLERLKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD25</accession>
    <name>A0A8T0HD25_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G028600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD25"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035811193" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0568557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="55" mass="6247" checksum="499F87D232154506" modified="2022-10-12" version="1">MALALKCHIRLAALPWLIPSPVGGCSARNLEHMTNLEQDEQFPSRRSELPRYMTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HDW1</accession>
    <name>A0A8T0HDW1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G127900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HDW1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0569951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="275" mass="30898" checksum="0F63E4A67590A239" modified="2022-10-12" version="1">MGRLISWEGDNKCQIEAEYVPKYYKGTGLFDFRWPIQIAAFLGRGAILEHILEHHVKFNSIHDHGFGNDKYDEYDESTPTIHCAALLGQVEAIQKILKYPIYDLNIQNWHGTALHLILKKTPCEAALKHFHTIALLHVLPNSQQYKRVKFGFHDSLWFKEDEGSRMFSAGELSSINLLLQAGIDIQTLHQYGYEPPTPGQNFNDEAKKWWYDKVVIEVATLKTSISSAANATSVIAALVATGSFIGPFQPPLGYANPGRLHTNQSKFGASILGMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHL7</accession>
    <name>A0A8T0HHL7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G145000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHL7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816855" description="Secreted protein" evidence="1">
        <location>
            <begin position="28"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="91" mass="10469" checksum="CB2B8C9739BEB596" modified="2022-10-12" version="1">MPTRQTRPPDRVALNAVFILLVTPTQSIVTSIPSPIAFCKACTSDSTSWFSNFSREFIKKILTQFIQLNISMKKNEHPTIYTYLNTKENRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HHM4</accession>
    <name>A0A8T0HHM4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Germin-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_6G145900</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Secreted</location>
            <location evidence="1 10">Extracellular space</location>
            <location evidence="1 10">Apoplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the germin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HHM4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048046">
        <property type="term" value="C:apoplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02241">
        <property type="entry name" value="cupin_OxOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006045">
        <property type="entry name" value="Cupin_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001929">
        <property type="entry name" value="Germin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31238">
        <property type="entry name" value="GERMIN-LIKE PROTEIN SUBFAMILY 3 MEMBER 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00190">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00325">
        <property type="entry name" value="GERMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00835">
        <property type="entry name" value="Cupin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="RmlC-like cupins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0052">Apoplast</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6 7 10" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0964">Secreted</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035965107" description="Germin-like protein" evidence="10">
        <location>
            <begin position="36"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Cupin type-1" evidence="11">
        <location>
            <begin position="83"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>oxalate</name>
            <dbReference type="ChEBI" id="CHEBI:30623"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" evidence="9">
        <location>
            <begin position="45"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR601929-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU366015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0570228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="25060" checksum="5764209BC33FFA2F" modified="2022-10-12" version="1">MGAYRSSQRSTLDLLKLLVVALCASTAFFLGDVHAADPDPLADFCVADLSPNAPLVNGYACKPRTNVTTDDFVYTGFRQAAASDAQIMQSPTGAVVSLAGPKEWPGLNTQGVTHARLDFAIGGVIPLHTHPRAAETLLVLKGTIYTGFISDDNVLYASTLKQGDVILFPKALLHFQLNVGNETAITFNTLTSQSPGLLLSANQIFEPNITSTVIEKSFGIDAATVKLLKASYPGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HI50</accession>
    <name>A0A8T0HI50_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G142100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HI50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035855602" evidence="1">
        <location>
            <begin position="18"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="14333" checksum="D366392355F83D96" modified="2022-10-12" version="1">MWWTFIIQALGFWNAGARYLLFLEDLVCSAMKELKRLILDTQRPGISECTSFEKRTDPQFVPLVGSAVLEIALRCFVHEGAGMCLKFFVVSYACSCVQYCSFCNVLLKMLPHRILDSVMSRETDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HJL4</accession>
    <name>A0A8T0HJL4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_6G202600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HJL4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000394">
        <property type="entry name" value="Leucine-rich repeat receptor-like protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000146">
        <property type="entry name" value="LRR receptor-like serine/threonine-protein kinase IOS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024788">
        <property type="entry name" value="Malectin-like_Carb-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45631">
        <property type="entry name" value="OS07G0107800 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45631:SF68">
        <property type="entry name" value="REPEAT FAMILY PROTEIN, PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12819">
        <property type="entry name" value="Malectin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="7 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="4 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035847811" description="non-specific serine/threonine protein kinase" evidence="13">
        <location>
            <begin position="33"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="566"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="629"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="915"/>
            <end position="940"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="916"/>
            <end position="928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0570986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="940" mass="101375" checksum="59D3BD02B680E87D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HK51</accession>
    <name>A0A8T0HK51_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_6G217400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0571179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HK51"/>
    <dbReference type="OrthoDB" id="541710at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003865">
        <property type="term" value="F:3-oxo-5-alpha-steroid 4-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006488">
        <property type="term" value="P:dolichol-linked oligosaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016095">
        <property type="term" value="P:polyprenol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039698">
        <property type="entry name" value="Dfg10/SRD5A3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624">
        <property type="entry name" value="DFG10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14624:SF0">
        <property type="entry name" value="POLYPRENOL REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02544">
        <property type="entry name" value="Steroid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="3-oxo-5-alpha-steroid 4-dehydrogenase C-terminal" evidence="6">
        <location>
            <begin position="240"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0571179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="41729" checksum="DA67A7AA7C084E22" modified="2022-10-12" version="1">MELGISIVLGLRIFWIALVVLCSIGCLPLGAAREFVLNIGHRGKLKLATTADNLPRFTVPQRWFTHFYLLGLLVNTALLTITFLFAYACTFPIQEHESQVSAIFSALGGAGTRDASGGIGTVEHLAEYRGRAWSSFLLLVMMEAQVLRRIFENFHVFQFSPLARMHVLGYLVGMGYYPAASFTLFTQHFQDRDYMSLISKFLLQRLGGAWILHTGPPLLNSQIKLQDYAKSLQGFEAFQWIGLAVFSLGWIQQYRTHCILASLRSKEVRTGVGAVFKPFAVDRKRANRYEIPRGSWFEWVSCAHYSAEIVLYAGIVIASGGNNINIWLLFLWVVFNLSLSARDTHQWYKTKFEDYPLFRRAIIPFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HMD1</accession>
    <name>A0A8T0HMD1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG058200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0571977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HMD1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0571977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="97" mass="10926" checksum="6185D60F690006DE" modified="2022-10-12" version="1">MVEEYMWISAKVFHTYGIDTRRLAKMAEMVIVSFSTRSKFYTIFMTEVIAVNTGLEIRASLRLAAGSRLGVLRVLFSSMQELMSGSITAEMVTICQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HQ75</accession>
    <name>A0A8T0HQ75_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG146300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0573072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HQ75"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035785370" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0573072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="110" mass="12295" checksum="63DB281A5F6BC6E0" modified="2022-10-12" version="1">MHSLVIICFGFAHLFGSGICASHGNQSINFIQTHRSMIAEFGLQFENNLAPVTGRILSAPQHCSVEVGFAIREVHSVQQLYHKHIRWNRPWFSCIKASGGADGRHHRGCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HTB8</accession>
    <name>A0A8T0HTB8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG232700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HTB8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="130" mass="14971" checksum="F7F00799442B797F" modified="2022-10-12" version="1">MALLDRKDTVHVHNQYVFPKHVSQIFFMDDGRDSDWKVVISHKPWSKRQMGEYDHRTFASVGHAPGTPSLFPVTMNSPDTFQQDSGYRSEAIEVPGPSIEFLDALQLVTEDDAYYDDDQYEEELIIYDGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HUR8</accession>
    <name>A0A8T0HUR8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_VG264900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HUR8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0574471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="45" mass="5151" checksum="99A14B2DFBC9147D" modified="2022-10-12" version="1">MVHTWLDSVLLSGRWQAVVVVVWREEGEGLRVNWKAGRRGSGIEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVA5</accession>
    <name>A0A8T0HVA5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_VG263100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0574453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVA5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052806">
        <property type="entry name" value="Fasciclin-like_AGP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33985:SF29">
        <property type="entry name" value="FAS1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33985">
        <property type="entry name" value="OS02G0491300 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035889411" description="FAS1 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0574453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="221" mass="23488" checksum="02BD86EC02E079AC" modified="2022-10-12" version="1">MATKTRDLKRFVDNMALVVLLMGTGIAEGKAGTPPILPKQYQGSGTVLQALLNQSWPAAQGLSATFTFFAPQNSAVKKYPCLFSESATVSKAVATNVLQYHIIPGKTLSYQQLKNLAQNADYMSTTAFNGKKLNVTLGGNKLNGYSSINYPDIGTKQSQAIHGIKTLLVPPGLTIGCGPPAPSVRGGNHSAASTPLAYQTRRRLTDFSIPVLSSILIGLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HVX4</accession>
    <name>A0A8T0HVX4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_VG325900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026426">
        <property type="protein sequence ID" value="KAG0575194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HVX4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome V"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035881285" description="Secreted protein" evidence="1">
        <location>
            <begin position="19"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="90" mass="10709" checksum="F7F41272CD41A006" modified="2022-10-12" version="1">MWIHGFFFCYQLFGWCRWLQGISHRSRWRVWRFDVVVELDFLPRDADNEAMTGPRSCPCSYLQHAMTWLGGWRGSEVETMLNTFRDTGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HWQ9</accession>
    <name>A0A8T0HWQ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G008600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HWQ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="317"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="344" mass="38273" checksum="E004BF99645BC673" modified="2022-10-12" version="1">MGNLGSSNRYEKVEVVRRLWKLQRAVPVLPISPHLIPLLVLSKRKDGYHVAGDVFSLCKPGNGKDWLKDVRPPLPRRKNKYFLPPKSIGQQTYVFSDDDGALAKALVGSANAAVWFKKFESIEVCISECEIREFNIEKWDEMMEHFDPDLQTTKPGSPECLSGNRELFIVQKVLLVSQIKITASYKGNAGPEVKSNVDPEMPSQGVNIEASFRTTSSSIIGEFALSAKQKNQKLPVAFSGFSYTYDKFGVREHFGKGTRCQADAEIGESSGASEEADSDDDDPQDDPNMGGLVDFNDGWFANVKPNPSLEIYPYVEESQEPLNAEEEEEEEEDEDEVVDPNAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HYT3</accession>
    <name>A0A8T0HYT3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G030800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0575785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HYT3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37223">
        <property type="entry name" value="OS08G0528601 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37223:SF1">
        <property type="entry name" value="OS08G0528601 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="38"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0575785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="14106" checksum="7089B0BE8143C5E5" modified="2022-10-12" version="1">MYVRERPGSLRGGETGHDDVRTRAREEESSSGGAETDSGERERVEARRGRRGSMRRRQEVAEVPSLLTLAVGSVIKLVCFAEFEILFVSFFVLAVLLFKDLTARPEYNQILVHRQFEEQTRLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZH4</accession>
    <name>A0A8T0HZH4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_5G091100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZH4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000095">
        <property type="entry name" value="protein STRUBBELIG-RECEPTOR FAMILY 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000305">
        <property type="entry name" value="PTI1-like tyrosine-protein kinase At3g15890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047117">
        <property type="entry name" value="PERK1-13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47982">
        <property type="entry name" value="PROLINE-RICH RECEPTOR-LIKE PROTEIN KINASE PERK4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47982:SF38">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="47"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0576580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="359" mass="40272" checksum="4DC10D4CDCA9F991" modified="2022-10-12" version="1">MARTSFWAKYWCYRPVDHNLCRIVDSKKPGTWRRFSLRELHAATNNFNYDNKLGEGIMGSVYWGQLASGDQIAVKRLKVWSAKAEREFAVEVEILGRVRHKHLLSLLGYCAEGQERLIVYEYMPHLSLYSHLHGHIAADSTLNWEQRMRIAVGSAEGLAYLHHYATPTVVHRNIKASNILLDDSLDALVADFGLAKLIPEGSLPKGSLKGISGYSAPNLGKVSESCDVFSFGILLMELISGRKPIRRVGGEKQSIMEWAGPLVLDGRYPDLVDAKLEGKFHQDELIRLVQVAVLCAQSFPEERPSMQDVVEMLKEGGQQFVKPPSQHGRDGLRLDEPVLYKTSTEATEVNNIFELAQLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HZY0</accession>
    <name>A0A8T0HZY0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_5G063500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HZY0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0576211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="107" mass="11923" checksum="1A615A43D9CE0BC0" modified="2022-10-12" version="1">MSVCGSGCFCGAILQVVIPSGRCSSGCKRIFSVVRTGRFLLQCKLDVTLSAKEGMRIFLFCLQLSDGYISSCIDQGLKRYYFESSSMLHISWNWFDNLSLVFVVLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0R4</accession>
    <name>A0A8T0I0R4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_5G127000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0R4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096:SF58">
        <property type="entry name" value="CHAPERONE DNAJ-DOMAIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43096">
        <property type="entry name" value="DNAJ HOMOLOG 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="188"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0577042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="469" mass="52340" checksum="AA99DA8747A0E970" modified="2022-10-12" version="1">MEATLWRSTPAHLLLSQSNNCSSSPRPLALTTQSVVGFLPGSNHGERCWSLRRAGASGRECFKHLREFVWVNSLESCGDPADHWVLGISGLSSSGGARGGSRLQRTGIGAGVLEWHSRGGCCQLRSTSLSDLTDMKCWASVQSLGQRIPCNLSRRWCIYKSRIRCAASREEDGGRQPRSYSQEVDVVDHYKVLGLRRQATASAIKLAYRQLARQLHPDVNKDADANEKFMSVRLAYEVLSDEASRKLYDSTLQEQAKASRRKQVYQRRERDTWLRNRSQYRRAPLEDSEWSYSVYSSENEYSNMESYYYTYPSSSSFSSKKKNPKPRKSNRGKSPEEDVRHRDWQVELQSIGKEALLFVWVVSAMWHALGAQTALGLLVGSLALWKDFAVGYRLASGVAWLMGGGKGLVLMVALIVTTRVLGRSYHGVAAIVSLALWLGGGVLRAVPLPHGAILVLVYKCIQLQSESSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I0X3</accession>
    <name>A0A8T0I0X3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_5G087400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I0X3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052254">
        <property type="entry name" value="CUL4-DDB1_E3_ligase_receptor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472:SF1">
        <property type="entry name" value="DDB1 AND CUL4 ASSOCIATED FACTOR 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44472">
        <property type="entry name" value="DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23761">
        <property type="entry name" value="Beta-prop_DCAF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="446"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="21"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0576531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="546" mass="59903" checksum="DDD9D274A027470A" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I165</accession>
    <name>A0A8T0I165_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl hydrolase family 88</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_5G077500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I165"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052043">
        <property type="entry name" value="PolySaccharide_Degr_Enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33886:SF8">
        <property type="entry name" value="UNSATURATED RHAMNOGALACTURONAN HYDROLASE (EUROFUNG)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="Six-hairpin glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0576403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="423" mass="47113" checksum="D836530B42A447D3" modified="2022-10-12" version="1">MMGSEAVGRILGACKRHEGVVWKSIVAVSVIAVVFARSSSTGTAMAMHISGQQALDYAERMATTAVNLWAVAGPAKDRFQYELGVVLRGIEVVYERTHEQKYFQFLKLKVDRFVNEDGTIRTYVFNEFQLDSILTGRLVLTLYNSTGESKYKTAADLLREQLRKQPRLSEGGFWHKKVYPYQMWLDGLYMAEPFYAQYAKEFKEPVAYDDIALQFIVAENRMRDAKLGLLYHGYDESRVSAWSDPATGHSPTVWGRAVGWYTMGLIDTLDFFPTEHANHPELLAILIRLATAVIRFQDAQSGLWWQVMDKGNDAGNYLESSASAMFVYTLAKGVRLGYLPREQFLECALKGYDGIISHFLQDSSATNGGAVTYTGTVAVGGLGGTPYRNGTYAYYLSEPVVSNDPKGVGPFIMASVEISVLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I200</accession>
    <name>A0A8T0I200_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="2 6">4.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G110200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>hydrogencarbonate + H(+) = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the alpha-carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0576821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I200"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03124">
        <property type="entry name" value="alpha_CA_prokaryotic_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.200.10">
        <property type="entry name" value="Alpha carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041891">
        <property type="entry name" value="Alpha_CA_prokaryot-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001148">
        <property type="entry name" value="CA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036398">
        <property type="entry name" value="CA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023561">
        <property type="entry name" value="Carbonic_anhydrase_a-class"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018338">
        <property type="entry name" value="Carbonic_anhydrase_a-class_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952">
        <property type="entry name" value="CARBONIC ANHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18952:SF208">
        <property type="entry name" value="CARBONIC ANHYDRASE XA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00194">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01057">
        <property type="entry name" value="Carb_anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51069">
        <property type="entry name" value="Carbonic anhydrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00162">
        <property type="entry name" value="ALPHA_CA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51144">
        <property type="entry name" value="ALPHA_CA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035958593" description="Carbonic anhydrase" evidence="6">
        <location>
            <begin position="32"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="Alpha-carbonic anhydrase" evidence="7">
        <location>
            <begin position="38"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU367011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0576821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="272" mass="30643" checksum="838CED0B9A52B29A" modified="2022-10-12" version="1">MIMTSQGRKCLYWTLTAYLCLQIISFGVVHAQEQGDDVRFDYGDGPNGPAHWGDLNVNWTKCKTGKYQSPMRITPDIMVTASKLGDLDAEYSSEPVAANISINVGYAVEVKVSPNSGLLKINGVRYRPQQFHFHLGSEHKILGHSFPMELHLVHTSEEDPNVRAVIAWLFVKGEDSPFLAQFDGKLPKPDSYPRIFSLPSITLPKLEESYARYQGSLTTPPCSEGVTWTVMLWNFPTISERQIQMFKAAMPKENVRPSMPSHGRRFRIHADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3A4</accession>
    <name>A0A8T0I3A4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Thioredoxin-like protein YLS8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_5G143700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DIM1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0577271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3A4"/>
    <dbReference type="OrthoDB" id="147752at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005682">
        <property type="term" value="C:U5 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02954">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000004">
        <property type="entry name" value="Spliceosomal protein DIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004123">
        <property type="entry name" value="Dim1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052:SF5">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEIN 4A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12052">
        <property type="entry name" value="THIOREDOXIN-LIKE PROTEN 4A, 4B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02966">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017199">
        <property type="entry name" value="mRNA_splic_U5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01410">
        <property type="entry name" value="DIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4 6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5 6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="disulfide bond" evidence="7">
        <location>
            <begin position="38"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR017199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR017199-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0577271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="142" mass="16603" checksum="322E02C930E5F344" modified="2022-10-12" version="1">MSYLLRHLHNAFHVDQAIKNEGERVTIIRFGCDSDTTCMEMDEVLMKVAEKIRKFAVIYLVDIKEVPDFNVMYELYDPCTVMFFFRNKHIMVDLGTGNNNKINWALKDKEEFIAIVETVYRGAKKGRGLVVSPKDYSTKFMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I3L2</accession>
    <name>A0A8T0I3L2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF4460 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_5G203500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026425">
        <property type="protein sequence ID" value="KAG0578082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I3L2"/>
    <dbReference type="OrthoDB" id="1888383at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 5"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028031">
        <property type="entry name" value="DUF4460"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027989">
        <property type="entry name" value="DUF4461"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027986">
        <property type="entry name" value="TCAIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31596">
        <property type="entry name" value="T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31596:SF1">
        <property type="entry name" value="T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14687">
        <property type="entry name" value="DUF4460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14688">
        <property type="entry name" value="DUF4461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4460" evidence="1">
        <location>
            <begin position="38"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4461" evidence="2">
        <location>
            <begin position="166"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0578082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="488" mass="55087" checksum="C942267615B0E039" modified="2022-10-12" version="1">MWACGWKLFLRRGVALGQGGQHILQAARWIHDDVHTLPKFKNELRRLYKLIHPDLLHNFPNEQATNLRSFQLLQEYLNAAKGGNTSSRFSYHFEFFIKDSSDDEAKDEKALQRVEVSLPPPQVKFHPQRGAEMLPGTKVAIGKLFAACGLSSEVSHGWVGDEHISLSDFFQQASELQRKDASVLNREQQVLMVKNAMKMRSGITVSFLPPLVDSSMESMEALEKLAQVLDRCKDIRLSGFALMIGDCYGIDALGNLWIDRNDRMESWLQFLRQVDLVDAAARKTSAKEWRFREFELAKAMQVAMVFTHTSLAATPAYSLFLSGMAEGAKTHGPVGAGNFSELPIRVAGAREMFDLQASSSQASGCYIDKVTGAVVVPVSASYLVISRFISDRGNEALLYRRKHEEERRRIEDLQVEARKRLKLRHLLFDSKLSNDQQATACARLLRSVPELIRYTEGLSLMISDEYRLPLPGSKGLAYLKWDFNISDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I4J2</accession>
    <name>A0A8T0I4J2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">60S ribosomal protein L44</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_1G060200</name>
        <name evidence="5" type="ORF">KC19_4G026800</name>
    </gene>
    <organism evidence="5 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I4J2"/>
    <dbReference type="OrthoDB" id="1875375at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.450.80:FF:000001">
        <property type="entry name" value="60S ribosomal protein L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.450.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_eL44"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053708">
        <property type="entry name" value="Ribosomal_LSU_eL42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="60S RIBOSOMAL PROTEIN L36A/L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="Zn-binding ribosomal proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0578490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0589966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="105" mass="11942" checksum="D0DDCF592934FEFE" modified="2022-10-12" version="1">MVNVPKTKKSFCPGKACKKHTLHKVTQYKTGKASLYAQGKRRYDRKQSGYGGQTKPVFHKKAKTTKKIVLRLQCQACKHVTQHPIKRCKHFEIGGDKKGKGTQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I5L4</accession>
    <name>A0A8T0I5L4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">arginine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">KC19_4G010400</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>tRNA(Arg) + L-arginine + ATP = L-arginyl-tRNA(Arg) + AMP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 12">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="2"/>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I5L4"/>
    <dbReference type="OrthoDB" id="68056at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd07956">
        <property type="entry name" value="Anticodon_Ia_Arg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000096">
        <property type="entry name" value="Arginine--tRNA ligase chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.730.10:FF:000017">
        <property type="entry name" value="Arginine--tRNA ligase, chloroplastic/mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1360.70:FF:000002">
        <property type="entry name" value="arginine--tRNA ligase, cytoplasmic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="entry name" value="Arginyl tRNA synthetase N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.730.10">
        <property type="entry name" value="Isoleucyl-tRNA Synthetase, Domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956:SF5">
        <property type="entry name" value="ARGININE--TRNA LIGASE, CYTOPLASMIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="ARGINYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0007">Acetylation</keyword>
    <keyword evidence="8 12" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 12" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arginyl tRNA synthetase N-terminal" evidence="14">
        <location>
            <begin position="104"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="DALR anticodon binding" evidence="13">
        <location>
            <begin position="566"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00049339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00055485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG0578269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="681" mass="75728" checksum="36A298EB34D6B322" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I6S7</accession>
    <name>A0A8T0I6S7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G050200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0578797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I6S7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0578797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="161" mass="17242" checksum="C7E29B29A2BD7955" modified="2022-10-12" version="1">MVSINKLPPDASSDSPPSGPALSLIHSQNSTPPARAESLHSDDPSLLTIPSLLLLLHLPHVPISPHRREIQNAATATLCDSTLPPQLRLNSECVNILATTTALPTTSGTLGPSPPARRPPVCECCSSRGALWFCVCAPHHRQPRSKPWQTSSSNHTFSELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0I7I6</accession>
    <name>A0A8T0I7I6_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G066300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0I7I6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036:SF2">
        <property type="entry name" value="OS04G0481300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036">
        <property type="entry name" value="OSJNBB0011N17.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="140"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="305" mass="34145" checksum="70624E69DD2E4B95" modified="2022-10-12" version="1">MAMVSLAQQATISSGTACFSSFSSSFYATQKNSFFLPPDSATSRRNLKHSGVMATPECSSSSGMTDSQGGRILRQVLNKEGRAKLNLTSDRGFYSSPRLVTHVDDQFLSTLTNLYRERIPDNAEVLDLMSSWVSHLPAEKKYKRVVGHGLNAQELSRNRQLDHFFVKDLNAEPKIENADGSFDAVVCTVSVQYLEQPEKVFAEIYRVLRPGGVCIVSFSNRMFYEKAVAAWRDGSDYSRTQLVKQYFQCIDGFTVPEVVKKLPDAKSSQNTSPNPFSFITNLFASAGRDPFYAVVAYRNFKPIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IA69</accession>
    <name>A0A8T0IA69_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Subtilisin-like protease</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">KC19_4G094200</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IA69"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02120">
        <property type="entry name" value="PA_subtilisin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04852">
        <property type="entry name" value="Peptidases_S8_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.200:FF:000006">
        <property type="entry name" value="Subtilisin-like protease SBT1.5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.80">
        <property type="entry name" value="Peptidase S8 propeptide/proteinase inhibitor I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="entry name" value="Peptidase S8/S53 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034197">
        <property type="entry name" value="Peptidases_S8_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010259">
        <property type="entry name" value="S8pro/Inhibitor_I9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037045">
        <property type="entry name" value="S8pro/Inhibitor_I9_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045051">
        <property type="entry name" value="SBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041469">
        <property type="entry name" value="Subtilisin-like_FN3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10795">
        <property type="entry name" value="PROPROTEIN CONVERTASE SUBTILISIN/KEXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17766">
        <property type="entry name" value="fn3_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05922">
        <property type="entry name" value="Inhibitor_I9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="Subtilisin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51892">
        <property type="entry name" value="SUBTILASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816094" description="Subtilisin-like protease" evidence="8">
        <location>
            <begin position="30"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="Inhibitor I9" evidence="10">
        <location>
            <begin position="35"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S8/S53" evidence="9">
        <location>
            <begin position="142"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="Subtilisin-like protease fibronectin type-III" evidence="11">
        <location>
            <begin position="677"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="6 7">
        <location>
            <position position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR615500-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0579378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="779" mass="83885" checksum="29A12CA3C32B43B2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IAF0</accession>
    <name>A0A8T0IAF0_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G101400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0579473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IAF0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0579473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="119" mass="12907" checksum="DF88F3F338679129" modified="2022-10-12" version="1">MRASFQSIFTAPPPAFILLSPAKIQLVGFRPPNCPGSGCARVHLLRARGSTSRHTAEVPIDARSRDWLYRDRSRPHASDCELACRLHRPGERVSDSSESIPVPAGHSVPSLATNTKPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0ICM3</accession>
    <name>A0A8T0ICM3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Knr4/Smi1-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G159300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0ICM3"/>
    <dbReference type="OrthoDB" id="1921190at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32011">
        <property type="entry name" value="OS08G0472400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32011:SF2">
        <property type="entry name" value="OS08G0472400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="313"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0580243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="58023" checksum="E6F128BAB06A6F06" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDF7</accession>
    <name>A0A8T0IDF7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G177600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0580498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDF7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0580498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7306" checksum="28CE88DFAE58DE8D" modified="2022-10-12" version="1">MLKSLESSSLDNVSQLPLDLLISLWLPSLTKRHKLACTRRINLERVPSKICWRPSTITCCRIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IDZ1</accession>
    <name>A0A8T0IDZ1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_4G265600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IDZ1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052298">
        <property type="entry name" value="ZMYND10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13244:SF7">
        <property type="entry name" value="ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0581612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="81" mass="9493" checksum="7AEE5DAE71B6234B" modified="2022-10-12" version="1">MYNSMQLRKYLNDLLTDQLPVLKDLKWAVEQLVIQVPQTTAESASGRLIIEQVPELREKLMTGKNWREEQCNLENSHCYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE76</accession>
    <name>A0A8T0IE76_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G230500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE76"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035850370" description="Secreted protein" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="56" mass="6384" checksum="F7AAC27887B7696F" modified="2022-10-12" version="1">MNKGIARKRDSRSTIFDFHVLCFCCLLQLGCGDGSCCRLTTVCHATMNPYLQRRDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IE77</accession>
    <name>A0A8T0IE77_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_4G241500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026424">
        <property type="protein sequence ID" value="KAG0581305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IE77"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0581305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="250" mass="26061" checksum="85757106022D8AA9" modified="2022-10-12" version="1">MTFNCEQCEKARKQFKKGRKSPPRSTRSTPSSRGSGSSSRSSGCLPKRKCPDKPVYVAADPADQTCIMVESNQPGGSSCSGSGNGPAGGGGGRGISFQFPGSSKELKLWMPGPESGPKDSNCIQIMGNSIVKTTSGGLQIIPCKAKGGGGNGGVQISLPRSAGGGTSCGGDQSDRGNMQLSISKTKGGQPLIDCEPGGKGMEITYGGDKKKLNVNHYKDTVASMINKRMTELEIEKKLADSSRGDIHDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IFM1</accession>
    <name>A0A8T0IFM1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G069900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IFM1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035816095" description="Secreted protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0582564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="75" mass="8368" checksum="772EA6532D752E18" modified="2022-10-12" version="1">MLILPDVLLLCVMHGLDMGTLSSFFTCSENASWCASCVLVRVQTHILRVVVRVYFESTGRLLDNRTQSCSSASER</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IGM6</accession>
    <name>A0A8T0IGM6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G031000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IGM6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="118" mass="13367" checksum="324CCE4BF5E43095" modified="2022-10-12" version="1">MILCGRLILRVQPYFEARDRQHEKAHAVLNQRLSDTRQRSPLGEDFAPVKPIIIGMNPQAQFYCQVGFHSRYEETGFQTPCSEKFSSGTHVSLCIAHILNLQVGWKNLIPTTSNAKAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIQ1</accession>
    <name>A0A8T0IIQ1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_3G152000</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:13066"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DNA2/NAM7 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000184">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd21407">
        <property type="entry name" value="1B_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18039">
        <property type="entry name" value="DEXXQc_UPF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21400">
        <property type="entry name" value="ZBD_UPF1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000097">
        <property type="entry name" value="Regulator of nonsense transcripts 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.230:FF:000002">
        <property type="entry name" value="regulator of nonsense transcripts 1 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.140.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041677">
        <property type="entry name" value="DNA2/NAM7_AAA_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047187">
        <property type="entry name" value="SF1_C_Upf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040812">
        <property type="entry name" value="UPF1_1B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018999">
        <property type="entry name" value="UPF1_CH/ZBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="DNA2/NAM7 HELICASE FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887:SF364">
        <property type="entry name" value="REGULATOR OF NONSENSE TRANSCRIPTS 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13086">
        <property type="entry name" value="AAA_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18141">
        <property type="entry name" value="UPF1_1B_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09416">
        <property type="entry name" value="UPF1_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51997">
        <property type="entry name" value="UPF1_CH_RICH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0347">Helicase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Upf1" evidence="15">
        <location>
            <begin position="166"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="531"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="C4" evidence="12">
        <location>
            <begin position="236"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1003"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1009"/>
            <end position="1020"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0583650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1308" mass="142257" checksum="0C53448BDDFD30F6" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IIV2</accession>
    <name>A0A8T0IIV2_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_3G063300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0582478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IIV2"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0582478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="168" mass="19528" checksum="170D62F48E82E08A" modified="2022-10-12" version="1">MLFLYFHVGLWSKMPLGELKPLLTHILPAGAMERLSFMYSRRDLIDRENFPWNYKTLGQVCSKVQSRNVCKLDQVLFVDVDPRSLRKTPNCMCYILWPFQGHLNFPNNDGVIPNIATDILPLVYPLHKFGSVPEYMAQACRPGQVHWAIEAARKFGRARVDWTEVCWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IJH3</accession>
    <name>A0A8T0IJH3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Desiccation-related protein PCC13-62</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G108500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IJH3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052965">
        <property type="entry name" value="Pigment-catalase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694">
        <property type="entry name" value="DESICCATION-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31694:SF19">
        <property type="entry name" value="DESICCATION-RELATED PROTEIN PCC13-62"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13668">
        <property type="entry name" value="Ferritin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035723544" description="Desiccation-related protein PCC13-62" evidence="1">
        <location>
            <begin position="26"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="42958" checksum="92C520F44B525E5B" modified="2022-10-12" version="1">MARIILTLSALILFSTLLLPSITIAEEQKENTDEAVAIAKEVEEGLETPFHYDSEDDTDTETEFEEKLESNPPHCKCPKRHHKHKKHRPHVRPEFSNRDVDELNLILNSEYLEAEFFLHGSYGFGLDKFNGTSVNVTGPKPIGAQKAHTGRFIEHLAKEFGLQSMGHIRELSKKLGEKAISRPEIDISRKAWGGLFNEAFGTKLKPAFDPYTTGNHFLLAAYMLPYVSYTGYVALGMHAEGSCARDLVARLAGVKGAEDASIRTVLYQRRRQVVERYNITVGEFTSVLSALREKLDRDNQTVTDPKKGNFTLPVTIDEGVLVPGTDTPEELLTGNIISVNENSLSVGRSPEQLLQVWYGTGNASIPGLFFPKGANGKIAAKYLSALR</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IKJ8</accession>
    <name>A0A8T0IKJ8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_3G138600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0583469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IKJ8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045283">
        <property type="entry name" value="AT3G44326-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33736:SF12">
        <property type="entry name" value="F-BOX DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33736">
        <property type="entry name" value="F-BOX PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00646">
        <property type="entry name" value="F-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00256">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F-box" evidence="1">
        <location>
            <begin position="14"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0583469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="367" mass="40163" checksum="776086C0AFBFE2B0" modified="2022-10-12" version="1">MAQVGHCDTGDQFLTNDVLRDVLDRLDGATLARASCVSKQFRSTGYEEAFWEKLCNERWPSTMEEPVKMLVSTAGGFRKLYNNSFPFILCDSHCGSGEEDKGEAISSSDFVSIVDVTYGGEPVLSRVVEGVSGAIAMCGPLVDILEVGRSESASDGHGAGASKEDDDRPLITIHTKLPRVSSIAQERKDGRFWSALCSHLRLSWILVNRKTQQMVNLGSWKPLGGIRHRPCGDDFLLRFGCILPTSSTPVHCNIVMRCITNTSMAVGSESSEGENAATTVVRVTELGMHLEDVHGVHLRGSQAISLLSRVMNCDKTVDESKVSASYKSFMATQISNQESLVRRENHRQTASAVFFVSVFVIAMSFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IN23</accession>
    <name>A0A8T0IN23_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sec16 Sec23-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_3G263100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0585164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IN23"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024298">
        <property type="entry name" value="Sec16_Sec23-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12931">
        <property type="entry name" value="TPR_Sec16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="5" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Sec16 Sec23-binding" evidence="6">
        <location>
            <begin position="1"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0585164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="184" mass="19872" checksum="5A57CB2C2990B873" modified="2022-10-12" version="1" fragment="single">MLVECGNTRDALKYCKTVLQTLKSAGMRSPEVEVCKALATSLEERIRSHMQDGSGSKLAPGKLVNKIKGTMDWGISKLIGGPPPSAPAADLWSCSVVLLAASRSRTLAGMRSRERQTGMRGYLQGQLDYAWRDLVGWAPTFCKGPAGCGAPTRKRRSWGTQINFITTPIVSELTSCAITHDSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IQ68</accession>
    <name>A0A8T0IQ68_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">soluble epoxide hydrolase</fullName>
            <ecNumber evidence="2">3.3.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_3G232200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Epoxide hydrolase involved in the biosynthesis of cucurbitacin and mogroside tetracyclic triterpene natural products (e.g. siamenoside I and mogrosides IV, V and VI). Cucurbitacins have cytotoxic properties and exhibit deterrent taste as a defense barrier against herbivores. Mogrosides are nonsugar highly oxygenated compounds used as high-intensity zero-calorie sweeteners; they also possess pharmacological properties such as regulating immunity, lowering blood sugar and lipid levels, protecting the liver, and acting as antioxidants and antitumor agents. Catalyzes the hydrolysis of aromatic epoxide-containing substrates, such as the conversion of 24,25-epoxycucurbitadienol to 24,25-dihydroxycucurbitadienol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(24S)-24,25-epoxycucurbitadienol + H2O = (24R)-24,25-dihydroxycucurbitadienol</text>
            <dbReference type="Rhea" id="RHEA:81855"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:229949"/>
            <dbReference type="ChEBI" id="CHEBI:229950"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:81856"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>an epoxide + H2O = an ethanediol</text>
            <dbReference type="Rhea" id="RHEA:19037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32955"/>
            <dbReference type="ChEBI" id="CHEBI:140594"/>
            <dbReference type="EC" id="3.3.2.10"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:19038"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Secondary metabolite biosynthesis; terpenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.2.10" evidence="2"/>
    <dbReference type="EMBL" id="CM026423">
        <property type="protein sequence ID" value="KAG0584758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IQ68"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 3"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004301">
        <property type="term" value="F:epoxide hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000161">
        <property type="entry name" value="Epoxide hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43329">
        <property type="entry name" value="EPOXIDE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="8">
        <location>
            <begin position="32"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00038334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00051067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00058358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00093212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0584758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="329" mass="36966" checksum="9500A42E51B1FD8A" modified="2022-10-12" version="1">MEVPSGKLPDIRHRMVKANGISMHIVEQGEGPTVLLLHGFPEFWYSWRFQIPALAEAGYHVVAPDLRGYGQTDAPKSSQLYTSCHLVGDLVGLLDALEEKRVFVVGHDWGAMVAWDLCLLRPDCVKAVICLSVPFFPRSPKGSSIKGYYETLGEGFYMCRFQKYGRAERDFARIGTTATLSKFLFPPRTSFIAPKDKELMDSIPMPKKLPQWISDADLRYYAQTYEKSGWTGALNLYRAMDKSWEIKAPWTSVGVKTPALFIAGDKDIVMGFPGVKAYVGRNFKSFVPNLKEIVTLKGGHFIQQEQPERVNELLIGFLNEQTLASSSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IRY5</accession>
    <name>A0A8T0IRY5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G094300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IRY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0586484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="125" mass="14374" checksum="D6A63F5E2734320A" modified="2022-10-12" version="1">MQETEYFIARNWRQGILCGLQSVGQSKTACVFTKSLAGFCDMFLHSIIVVQRQFLHQYNYQISFVTQQPLIQLLQITLVLSEIPENTTQTYTTQTYSCSCTYIRFVLDCYKTIFPESGLTSKATI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IS03</accession>
    <name>A0A8T0IS03_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G044600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0585857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IS03"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036273">
        <property type="entry name" value="CRAL/TRIO_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46277:SF24">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46277">
        <property type="entry name" value="OS03G0850700 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46938">
        <property type="entry name" value="CRAL/TRIO N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="1">
        <location>
            <begin position="158"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0585857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="341" mass="37893" checksum="1EC7F2ED4E2756AF" modified="2022-10-12" version="1">MAAQVHAVCANIHSPCCSYSGPARCRSTTVTSGGAALRDSVKSLQCSTASSSFSSCVRTHRQSGLFPARRIVERTVLRRSVENSVEVDSEEIVDSFEESLIRMRELVDLAGGTSKGVDDASLMRFLKGSSLNVDEAAKAFAKHQQWETSFKPKGFISEVEIANELNAKKSYLQGRDKQGRPICVILARNHTANKEDFDEFRRFIVYSMDKILTAASDSTDGKINCIIDLEGLGFKNLDSKAFIAGFDMYQSHYPERIERFYMVNAPLIFNGLWKVVRSFINETTSKKIVFVDKKKAQETLLSVIDADQLPKEYGGTADLVLLQDAFVPGWPPAKQEFSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVC1</accession>
    <name>A0A8T0IVC1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G182500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVC1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0587674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="163" mass="18263" checksum="58D413028F33D4F4" modified="2022-10-12" version="1">MNSLDRTRLDGTGQKWGGARVREEAEGHAIRSLPRPSPTCRKNCNSASVGAWNWKWQRRRSCSQAKLWRIASTATAHPRRHRHTSDAPRRTSTTASHQARSISRLQCHCAATWGVGRDVPARHLFLAPHRIITTIIASSSQILPAPSSAHDTGQLLIRERLRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IVR5</accession>
    <name>A0A8T0IVR5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNase III domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_2G127000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0586916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IVR5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="entry name" value="Ribonuclease III domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01468">
        <property type="entry name" value="RNase_Mini_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008226">
        <property type="entry name" value="Mini3_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34276:SF1">
        <property type="entry name" value="MINI-RIBONUCLEASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00636">
        <property type="entry name" value="Ribonuclease_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="RNase III domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase III" evidence="4">
        <location>
            <begin position="42"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0586916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="217" mass="24323" checksum="81DC0A96519E0E17" modified="2022-10-12" version="1">MAMALQQRWSCSWPWIATPGDGDAALSSRPRRQRPPRVDLRRLLDRAAVANSESASAVQDNAKVWLPSPPPVERPRAVHNAASLAYLGDSIYEVYVRRHFLTPPQNVDSYNKRVMSLVCCEAQDAMLQQLLKCNFLTDEERDVVRWGKNIDTGQRRASRRAGSKAYSSASALETLIGYLYLTNQERLEELMTKVGFNVDSNSLLIGFGFQTADKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IX95</accession>
    <name>A0A8T0IX95_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_2G236900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0588350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IX95"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044714">
        <property type="entry name" value="AtSIBP1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672:SF8">
        <property type="entry name" value="BTB DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46672">
        <property type="entry name" value="OS08G0495500 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTB" evidence="2">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0588350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="236" mass="26950" checksum="25C1D0BD76954A4E" modified="2022-10-12" version="1">MALPICANIDLTKFLLLDNLKTKVQWKCPVYVVKMLEEATHADITFEVAGGGSVKAHRDVLANVSPVFAAMFRHDMKEILTATVKISDMTIDGLKLFLILLYTTKDVNDAGIVELNHAVDKYFKEFHNATKQYQVESTLGSLFICALERNLNPDNCWIYYRSFRKGSIGSFTCYNYILEHYDEVIMSDSFLETMKQNPGCVCHVVREARNIISRAMALETCRATKRRRVTEKTIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0IXL3</accession>
    <name>A0A8T0IXL3_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_2G204400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0587955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0IXL3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0587955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="12423" checksum="5C6323B964D32D00" modified="2022-10-12" version="1">MELKLTFSLIVSFISFKAFNAISDYLARVQLFSKLKLENQRVSNELQDVKVTCLCLLVYDYLSRHFFSIICFVPQCLSSLKHQYLLLLYLGKLSVASNNFRYCRFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J000</accession>
    <name>A0A8T0J000_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pectate lyase</fullName>
            <ecNumber evidence="3 8">4.2.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G010600</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Eliminative cleavage of (1-&gt;4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.</text>
            <dbReference type="EC" id="4.2.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="8">Binds 1 Ca(2+) ion. Required for its activity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Glycan metabolism; pectin degradation; 2-dehydro-3-deoxy-D-gluconate from pectin: step 2/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the polysaccharide lyase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.2" evidence="3 8"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J000"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030570">
        <property type="term" value="F:pectate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="entry name" value="Single-stranded right-handed beta-helix, Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018082">
        <property type="entry name" value="AmbAllergen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002022">
        <property type="entry name" value="Pec_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045032">
        <property type="entry name" value="PEL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31683:SF187">
        <property type="entry name" value="PECTATE LYASE 18-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00807">
        <property type="entry name" value="AMBALLERGEN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00656">
        <property type="entry name" value="Amb_all"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0106">Calcium</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Pectate lyase" evidence="9">
        <location>
            <begin position="115"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0589294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="346" mass="38306" checksum="E906F025AEFF4736" modified="2022-10-12" version="1">MHRTIPPFRRASTWWSTTTRRSQLRKLKCFFWPRPTDVERGIPWTIAGMATPTGRYGVRAWPAPPLGLAGAKTGSKRQVYVVTSNRDDNPVNPAPGTLRYAVTRPEVLQIIFAGSMTIKLKNELLNTSFKTTYSCGLTVHIVEGGGLTVQRVSNVIVHGLVMHDIISTGPGRIMTSTKHVSNRGRCDGDAISIFASKDIWIDHCYFSNAADGLAMLLGAPKDDFMDRKFFVTVACNHFASGLVQRMPREAPTILSQRNVFNVCKSDEQVTKRINDGGPSFGGPKNWKWKSKGDSFQSGSYFSGVAMAWSAQSYSKTRSCSSHPRSMVWKMVKGAGPLNCRHEVRCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J031</accession>
    <name>A0A8T0J031_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G012800</name>
        <name evidence="3" type="ORF">KC19_1G013100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J031"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0589324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="102" mass="11495" checksum="B41C6CA246EF9C5F" modified="2022-10-12" version="1">MHPCYEVESVRTSQGSILTISPPHNAHMAKARDDHDMTDPDSSRSSTPHCNRFKQDSHDSFSIPKTQHQAGFSHELDNTHFDFQCALPITTPKTCTPNDFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J0I7</accession>
    <name>A0A8T0J0I7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_1G022900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TMEM104 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J0I7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189:SF0">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16189">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN 104-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="13"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="10">
        <location>
            <begin position="124"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0589474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="478" mass="52654" checksum="628BDE1106E70479" modified="2022-10-12" version="1">MASAESSHGSQYSPFVAFIFLYNLMVGTGCLALPSVLLKGGWVLGTSFVLIVAFLSYVSVTFVLESMATANALIKLKSRDRLDESLLSEEAGQPGDDFPSEESHSLDKPSEEGIFEISKKIEMGEMAGMFFNQWGIIVFYSALILYLIGDSIIYSTLIARSLSEFFVNLTPASWAFDMYLVIFFCFSLPLCYFDFQKTKLLQMTTLAIRNISLYTMIILAAMKAVNGDRKDSDVPTVNLSALPNLFGGAVYSFMCHHSLPGIVTPMRNKSHLQRISGLAYGSVVVVYILLLVSSGFAFGVNVKDPLTFNFPADQYGLVGNLLFLFPVFTLSSTFPMLSITLRNNIDTLLQFAFNSEASSPPEESKLRRLMLTLLAVVPPTLLSYFAKHANISVDELVGFTGAFAGCAVMLIIPAGLVYCSRKIFSTEWDSQKGSRIPKPSNYHHSPFAGQGWVAAVLAWAVLSLIFNTYEKWNKLPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1R1</accession>
    <name>A0A8T0J1R1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G289200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1R1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="85" mass="10130" checksum="F8C9CBD492EBDAFE" modified="2022-10-12" version="1">MLFSKCFFHWFCSMSCLYCTVLAGVCRRYSRRVLDRNSGLREMNWIEPKNMLVLSQSLWLDHLKLPIPLERAMYRIGYRPGSCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J1V8</accession>
    <name>A0A8T0J1V8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein EFR3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_2G292500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026422">
        <property type="protein sequence ID" value="KAG0589119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J1V8"/>
    <dbReference type="OrthoDB" id="19232at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049152">
        <property type="entry name" value="EFR3-like_ARM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055296">
        <property type="entry name" value="SRL2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46087:SF11">
        <property type="entry name" value="PROTEIN SEMI-ROLLED LEAF 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46087">
        <property type="entry name" value="PUTATIVE, EXPRESSED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21052">
        <property type="entry name" value="EFR3_ARM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1057"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1068" mass="116436" checksum="6B2154546DC74DAC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2C2</accession>
    <name>A0A8T0J2C2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_1G069400</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000779">
        <property type="term" value="C:condensed chromosome, centromeric region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043515">
        <property type="term" value="F:kinetochore binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008608">
        <property type="term" value="P:attachment of spindle microtubules to kinetochore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140694">
        <property type="term" value="P:membraneless organelle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000278">
        <property type="term" value="P:mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042327">
        <property type="term" value="P:positive regulation of phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901987">
        <property type="term" value="P:regulation of cell cycle phase transition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033044">
        <property type="term" value="P:regulation of chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd01374">
        <property type="entry name" value="KISc_CENP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.850.10:FF:000026">
        <property type="entry name" value="Centromere-associated protein E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019821">
        <property type="entry name" value="Kinesin_motor_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF75">
        <property type="entry name" value="CENTROMERE-ASSOCIATED PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00411">
        <property type="entry name" value="KINESIN_MOTOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0505">Motor protein</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="9">
        <location>
            <begin position="3"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="564"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="807"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1319"/>
            <end position="1344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1359"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="342"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="398"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="596"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="652"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1116"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="564"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="819"/>
            <end position="830"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1372"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0590074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1399" mass="157917" checksum="3A41155CB2ECCF9D" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J2M1</accession>
    <name>A0A8T0J2M1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G017600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0589379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J2M1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035718461" evidence="1">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0589379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="64" mass="7382" checksum="CAC0D75723DD2FCF" modified="2022-10-12" version="1">MPHITQLWPLLFSVLSQLVHMVTWIPDPLYNIISEIGRRATWICANDRTALSKTRGSELNIFTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J4C9</accession>
    <name>A0A8T0J4C9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G069200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J4C9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000060">
        <property type="entry name" value="Glycosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0590072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="487" mass="54186" checksum="E21294C41A75FCEB" modified="2022-10-12" version="1">MENGNSAIRPHAVIFPFGALGHIRPLEQLARRLAHVYGFKVTFVVTSHFYKRMDFTDSKNGDDSIQYMDLEEGFPDSYYHMTALKTLVFALGTLGPSLKELLGRIHSEVHPVTCVISDQVFTEAHRTALHHGIPSVAFVTSSAMAVTAKYYGPRFIEEGLLPIPKSPAEAKEALSQTVTIVPGMHPMKLGDYHSGLWVNDITEPFFQYVIGDHSKNLHERDWILVNSIYELEAPLLEAVQQDVGIKFTTVGPLAITPITTTEPFDVNNNEDNKISNYSPEEKKCMDWLNKQEPTSVIYVSFGSFAVISASNLEKILLGLEDSQVPILMVMRPDLLEGNQSSIKGFQERTKERALFVSWAPQLKILAHSAIAGFLTHGGWNSFLESISMGVPFLCHPFFVDQPMVSRYIASVWKVGLELKQEDGTLDRVDVEQKVRALTAKESGIRANAAAWRDVVRGAVEDGGSSQRNMVAFVADMCKRAQAVKSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J5S4</accession>
    <name>A0A8T0J5S4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_1G075700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0590143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J5S4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0590143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="110" mass="12405" checksum="9AEC07C28CBAD9A7" modified="2022-10-12" version="1">MLSSELQAFTLSHFFEGNGCLSHEWALERRNWGSGWFILTILQHVCRCCSNYLRQAIPVSSSARVTLWSGVSIPILRLPQRMNMSSAISHHSITSIPYKSKCGILARNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J784</accession>
    <name>A0A8T0J784_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycosyltransferase N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G147500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-glycosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J784"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058980">
        <property type="entry name" value="Glyco_transf_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926">
        <property type="entry name" value="GLUCOSYL/GLUCURONOSYL TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11926:SF774">
        <property type="entry name" value="UDP-GLYCOSYLTRANSFERASE 85A1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26168">
        <property type="entry name" value="Glyco_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycosyltransferase N-terminal" evidence="2">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF26168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="316" mass="35021" checksum="192FF1ED5B0E65B5" modified="2022-10-12" version="1">MESIPPPHVVMVPMSAPGHAMPFVHFAKQLAACGITITYVSSDKHISHLREALGTLDYTREGLQLRFLGLRDSEEELPTSGSPQEKIIDLFNPIPFLVSRDFAPGCYPSERPEKIVAIKLLEELVIDVGSSESQKLRGVAPAGPPMCILHDIFTTRAQVVADKLHIEKHLLCVSPVHYLAGNLQSERLAQEGRLPITSREARDTVISDIPGLQPCHPSDLSGAFCNPTIYNWMKYHHYRLGRANVILVNSFYELEKQSIDAVRNEVLGTGYVKTEHLFDIGPLSSDTDQTNIGESVVEKQHPCLTWLDTQAPSSVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J927</accession>
    <name>A0A8T0J927_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_1G168800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J927"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036">
        <property type="entry name" value="OSJNBB0011N17.9 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43036:SF1">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="1">
        <location>
            <begin position="182"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0591348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="319" mass="34945" checksum="F82426898D95CFD2" modified="2022-10-12" version="1">MTRALGMAATSVGPALRNVARGVGAVDSGVGSSSRRTICALARSGSTKHQALQHLHQLCGGFLSPTSRRRFLQGAGMLGMMSSAPLRAQAAGVSEAEEVLKNVQWPEQFPFSKEDFARYDESPDTSFYDAPRFVTHIDDPAIRALTKYYSSALPPSNTPGVAVLDMCSSWISHYPKGYKQERIVGLGLNEAELQRNEVLTEHVVQDLNNNPTLPFADNSFDVITNVVSVDYLTKPMEIFKEMHRVLKPGGLAAMSFSNRCFFTKAISIWTSTGDIDHVMIVGSYFHYSGGFEPPQALDISPNPGRSDPMYVVYSRKLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0J988</accession>
    <name>A0A8T0J988_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GST C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_1G181400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0591529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0J988"/>
    <dbReference type="OrthoDB" id="2309723at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03190">
        <property type="entry name" value="GST_C_Omega_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1050.10:FF:000045">
        <property type="entry name" value="Glutathione S-transferase family protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047047">
        <property type="entry name" value="GST_Omega-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016639">
        <property type="entry name" value="GST_Omega/GSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419">
        <property type="entry name" value="GLUTATHIONYL-HYDROQUINONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32419:SF31">
        <property type="entry name" value="OS02G0814800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13410">
        <property type="entry name" value="GST_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13409">
        <property type="entry name" value="GST_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01206">
        <property type="entry name" value="Xi.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01148">
        <property type="entry name" value="Xi_(cytGST)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="2">
        <location>
            <begin position="252"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0591529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="417" mass="46152" checksum="46492FA93BD8A8DF" modified="2022-10-12" version="1">MASLITASTCLSTSFLPSSDTSRAFQAKGVHSQKSIRTRIRSGMEDKSSSSWSKSPADLVKLLGQNLWGRSLPPGALVSVVKEVWTTGWQTMMAQLAPPTESRDYNRPTSQFRNRPQPSSANPGQFHLYVALACPWAHRTAIVHSLKGLRDGVPISVAVPGSTGLWEFSPKPDTTTTTHPTLKPTLDRANGQKRVADVYKSQPGGYNGRSTVPMLWDASQKRVVNNESADIIEILNSDFNHMALNPGLDLAPAHLKGEIEAWNEVIYPNINNGVYRCGFAQSQEAYDSAVESLFNALDKVEAHLASSRYLCGDVFTLADVRLFTTLFRFDPVYQILFKCSKQKLAEYENLQGYMRDVYQIPGVAETCDMDAIMYGYYKVLFPLNPGGISPAMPRVADSRALLEPHHRHKISSQVVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JAF8</accession>
    <name>A0A8T0JAF8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromo domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_1G257000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0592495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JAF8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00024">
        <property type="entry name" value="CD_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051219">
        <property type="entry name" value="Heterochromatin_chromo-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056924">
        <property type="entry name" value="SH3_Tf2-1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22812">
        <property type="entry name" value="CHROMOBOX PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24626">
        <property type="entry name" value="SH3_Tf2-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chromo" evidence="3">
        <location>
            <begin position="135"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0592495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="192" mass="22922" checksum="530A17C78ED16B78" modified="2022-10-12" version="1" fragment="single">RTKQHPDNDKFKIQDNLLYFEDRVYIPEGPLRLRVLQSHRLRKESPVFHVGDKVWLLRRNIKTSRPCDKLDYRRLGPFCIQEKINPVAYRLELPASMKVHPVFHVSLLESYKESTISGRLQPSLPSVEVENHEEYEVEEVLDSRRRRGKLQYLIHWRGYDISERTWELAANLANAPLKVQEFHQRYPEKPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JD76</accession>
    <name>A0A8T0JD76_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">KC19_1G297200</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JD76"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.80.10.10:FF:000400">
        <property type="entry name" value="Nuclear pore complex protein NUP107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000015">
        <property type="entry name" value="Somatic embryogenesis receptor kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000016">
        <property type="entry name" value="Somatic embryogenesis receptor-like kinase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050647">
        <property type="entry name" value="Plant_LRR-RLKs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056">
        <property type="entry name" value="LRR RECEPTOR-LIKE SERINE/THREONINE-PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48056:SF81">
        <property type="entry name" value="RECEPTOR PROTEIN-TYROSINE KINASE CEPR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00019">
        <property type="entry name" value="LEURICHRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="14 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="8 20" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="13 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035715108" description="non-specific serine/threonine protein kinase" evidence="20">
        <location>
            <begin position="28"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="229"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="21">
        <location>
            <begin position="293"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="18">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG0593002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="618" mass="67586" checksum="9E61D359D3C16360" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-06-18" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JDJ0</accession>
    <name>A0A8T0JDJ0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_1G336100</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03232">
        <property type="entry name" value="ABCG_PDR_domain2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000179">
        <property type="entry name" value="ABC transporter G family member 34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000059">
        <property type="entry name" value="ABC transporter G family member 40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029481">
        <property type="entry name" value="ABC_trans_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034003">
        <property type="entry name" value="ABCG_PDR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013581">
        <property type="entry name" value="PDR_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040:SF28">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 39-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48040">
        <property type="entry name" value="PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14510">
        <property type="entry name" value="ABC_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08370">
        <property type="entry name" value="PDR_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="549"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="582"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="622"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="667"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="692"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="775"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1242"/>
            <end position="1260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1267"/>
            <end position="1285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1317"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1352"/>
            <end position="1376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1382"/>
            <end position="1403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1410"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="1465"/>
            <end position="1490"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="178"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="12">
        <location>
            <begin position="893"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0593525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1495" mass="168044" checksum="3E6C9CD89BA106A0" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0JE94</accession>
    <name>A0A8T0JE94_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_1G297100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026421">
        <property type="protein sequence ID" value="KAG0593001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0JE94"/>
    <dbReference type="OrthoDB" id="1911901at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017887">
        <property type="entry name" value="TF_TCP_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005333">
        <property type="entry name" value="Transcription_factor_TCP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31072:SF170">
        <property type="entry name" value="TRANSCRIPTION FACTOR TCP15-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31072">
        <property type="entry name" value="TRANSCRIPTION FACTOR TCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03634">
        <property type="entry name" value="TCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51369">
        <property type="entry name" value="TCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TCP" evidence="7">
        <location>
            <begin position="99"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="24"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="189"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="265"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="401"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="505"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="28"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="44"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="215"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="296"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="313"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="405"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0593001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="54088" checksum="5CDA2ACDF63A8A3E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G4P2</accession>
    <name>A0A8T0G4P2_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_12G075100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G4P2"/>
    <dbReference type="OrthoDB" id="10265467at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017116">
        <property type="term" value="F:single-stranded DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000731">
        <property type="term" value="P:DNA synthesis involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00009">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18139">
        <property type="entry name" value="HLD_clamp_RarA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.272.10:FF:000001">
        <property type="entry name" value="Putative AAA family ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000137">
        <property type="entry name" value="Replication-associated recombination protein A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.272.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3710.10">
        <property type="entry name" value="DNA polymerase III clamp loader subunits, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051314">
        <property type="entry name" value="AAA_ATPase_RarA/MGS1/WRNIP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779:SF7">
        <property type="entry name" value="ATPASE WRNIP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13779">
        <property type="entry name" value="WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22562">
        <property type="entry name" value="UBA_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="post-AAA+ oligomerization domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBA" evidence="6">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="85"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="121"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="545"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="550"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0554233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="785" mass="85321" checksum="5B3A5C1592F3460F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G633</accession>
    <name>A0A8T0G633_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G081400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G633"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="156" mass="17184" checksum="D078522D8017CCB9" modified="2022-10-12" version="1">MHAQSPYSEPSKQATIPENSNEMHYSPKKRKIQNRLTFTASIPLSSSRTSHLLSSPLILVTNTSHTKTQTPTPHTHNPPGNHHSSNSLHALSLSRSLSLALSLSLSLTLSLYARSDGTIPEKQSVTCIRSITEFTPRSSAIKHKHTHTHTLESFST</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7G1</accession>
    <name>A0A8T0G7G1_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_12G083300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7G1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0554334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13567" checksum="77AA36F3254869DC" modified="2022-10-12" version="1">MHSKQNSILNRSIPHRNIKTEGILSLYLSQLSVLNHANSPSLTETNSTRPVSLLDNSIYTKCRMQIINNERGSRAPVVLQSTSGVLAKGMIISTILRKIGLDNFATGNEQRQGYQTLTTTNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G7W1</accession>
    <name>A0A8T0G7W1_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_12G162500</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the leguminous lectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G7W1"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd06899">
        <property type="entry name" value="lectin_legume_LecRK_Arcelin_ConA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14066">
        <property type="entry name" value="STKc_IRAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000162">
        <property type="entry name" value="Adenine nucleotide alpha hydrolase-like domain kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000336">
        <property type="entry name" value="Cysteine-rich receptor-like protein kinase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052059">
        <property type="entry name" value="CR_Ser/Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001220">
        <property type="entry name" value="Legume_lectin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47973">
        <property type="entry name" value="CYSTEINE-RICH RECEPTOR-LIKE PROTEIN KINASE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00139">
        <property type="entry name" value="Lectin_legB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="295"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="357"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="671"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="676"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0555343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="694" mass="77103" checksum="0F966066E4BAC97B" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0G963</accession>
    <name>A0A8T0G963_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G008000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0555846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0G963"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0555846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="73" mass="8459" checksum="C74F900C963F4354" modified="2022-10-12" version="1">MLNFWSGHNASLFFGCLHFTVNVLSCMTANLFPAKYSKFGVTCFDIAQIIILKHSRKLLLFDIFDLERTHLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GAT7</accession>
    <name>A0A8T0GAT7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_12G133200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0554958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GAT7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035779944" evidence="1">
        <location>
            <begin position="20"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0554958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="155" mass="17233" checksum="9EBB25D61C91FDF7" modified="2022-10-12" version="1">MDSTHGPTVLILFAPSVVALTSDGLALIELKNGLTTKFPLFETSTVLVHRNFWSEIETVGNAKHRNKVRLVGFVKWGKVGLLLHDYVLNVFNVFNEISIRFCTRVKPEVMMSMSSHGKTSYCGWCGPGNNIPSPCNPSIVHRHTKSSNVLNGLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GB23</accession>
    <name>A0A8T0GB23_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DUF1475 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G047600</name>
        <name evidence="3" type="ORF">KC19_11G047800</name>
    </gene>
    <organism evidence="2 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GB23"/>
    <dbReference type="OrthoDB" id="611851at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009943">
        <property type="entry name" value="DUF1475"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36318">
        <property type="entry name" value="OS06G0581300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36318:SF3">
        <property type="entry name" value="OS06G0581300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07343">
        <property type="entry name" value="DUF1475"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0556361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0556363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="134" mass="14940" checksum="E7F86E0CEBEEDCBD" modified="2022-10-12" version="1">MVSSVVIGRYVFLALGLSTACTVLYTCITDGSPFRSELLTPWMSATLIDFYVNVIAIAAWVWYKESSLASRLIWIALLVCFGSITTCWYIAIEFFKMSPDDPVHYVLLKDRTIRWTSSGSVLDSTGNGNAPSMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GBX3</accession>
    <name>A0A8T0GBX3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Sodium/metabolite cotransporter BASS3, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_12G173500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast envelope</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026433">
        <property type="protein sequence ID" value="KAG0555499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GBX3"/>
    <dbReference type="OrthoDB" id="203097at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 12"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009941">
        <property type="term" value="C:chloroplast envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004710">
        <property type="entry name" value="Bilac:Na_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361">
        <property type="entry name" value="SODIUM-BILE ACID COTRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10361:SF33">
        <property type="entry name" value="SODIUM_METABOLITE COTRANSPORTER BASS3, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="386"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="446"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="71"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="75"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0555499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="486" mass="52123" checksum="BDA8A196BDA55EF3" modified="2022-10-12" version="1">MAASLVKSVPNFRSVALPSGTPTRSDAVSNCSTSSSSSVFLGSSLPKHDLFYYGFIRRAELFHVLQCSAKYRGPSGDKSRPPSEKSKRHLDGCNSKGNEDGFKPLASSSQNPLASTSYEGQEQATIEMTRARHKGRVGTYIREGNVSLASFGIKVKRDKKGQKVDLTKSLSQLLPYVVLATAVSALAQPASFAWVSKDYYAALLGGIMLSIGVQLSVSDFAIVLKRPLPVLVGYVAQYMVKPLLGLLVCAAFGVDPLFSSGLILTSCVAGAQLSSYAAFLSEGDVALSIILTSVTTITSVVITPLLTKLLIGSVVPVDVIAMGKSILQVVILPIVLGLGLNTYAKKFVDKIRPVMPLMAMVCTSLCIGSPLSMNRNRIVSIEGFRLLFPVLTFHISAFVLGYWVPRLPFWRQDEKVSRTISLCTGMQSSTLAMLLATQFLGGSHAVPPACSVVVMAIMGLSLASFWGKGHQIRNLKNLVLKDVSYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GCJ9</accession>
    <name>A0A8T0GCJ9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_11G103200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GCJ9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="65"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0557116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="103" mass="11556" checksum="66642175355FC9D6" modified="2022-10-12" version="1">MKTCIQHHTHQKTTILSPSLHTINQHQQQPSCQPTNSTSLSSPKSINLTITTTLTCTPSTADTDLYQQNPKPESSTKIIKPNQTKRRDVICLQLIISATKRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GEC7</accession>
    <name>A0A8T0GEC7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UBR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_11G124500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0557373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GEC7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15542">
        <property type="entry name" value="PHD_UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd19677">
        <property type="entry name" value="UBR-box_UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040204">
        <property type="entry name" value="UBR7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047506">
        <property type="entry name" value="UBR7-like_UBR-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003126">
        <property type="entry name" value="Znf_UBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13513:SF9">
        <property type="entry name" value="E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02207">
        <property type="entry name" value="zf-UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00396">
        <property type="entry name" value="ZnF_UBR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51157">
        <property type="entry name" value="ZF_UBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="UBR-type" evidence="6">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="UBR-type" evidence="4">
        <location>
            <begin position="39"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0557373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="426" mass="47364" checksum="1DD1C37128E8689A" modified="2022-10-12" version="1">MAAMEENEDEGVSTLAEYMERVEEQELEADLVLGGDDGKECTYRQGYMKRQAVFSCLTCTPDEEAGFCTACSLACHDGHDVVELWTRRHFRCDCGNSKYGQGICKLRADKDIENSENVYNQNYKGVYCTCHRPYPDPEGAALGEMLQCCICEDWFHELHLGLPPTLQFPRDEEGEPLFDEVICNSCVPKCPFLSKYPDVVIAPATVLDASTDPVEIVEQTHGSGVENGKPSPLGPTTDPKAECSPENGIVDIHQVNSAVGEVSNEAKEEREVKQEVQPSNETAANEDVTNGYHCELGKESPAAIIQPGHPLFLIKSWRAQLCRCPNCLRMYEERGVGFILDSDDTLQAYEASAKRKREETRAQVDGSDLMQGLGHVQQIELLHGFNDMTAQLKNFLAPFGESGRTVTSADIHGFFADLNQKKRRHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GFH7</accession>
    <name>A0A8T0GFH7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), chloroplastic</fullName>
            <ecNumber evidence="11">1.17.7.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_11G088200</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced [2Fe-2S]-[ferredoxin] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:26119"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:58483"/>
            <dbReference type="ChEBI" id="CHEBI:128753"/>
            <dbReference type="EC" id="1.17.7.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the IspG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.7.1" evidence="11"/>
    <dbReference type="EMBL" id="CM026432">
        <property type="protein sequence ID" value="KAG0556909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GFH7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 11"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046429">
        <property type="term" value="F:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019288">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.20:FF:000005">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.413.10:FF:000006">
        <property type="entry name" value="4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="entry name" value="Dihydropteroate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.413.10">
        <property type="entry name" value="Sulfite Reductase Hemoprotein, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00159">
        <property type="entry name" value="IspG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017178">
        <property type="entry name" value="IspG_atypical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004588">
        <property type="entry name" value="IspG_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058579">
        <property type="entry name" value="IspG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058578">
        <property type="entry name" value="IspG_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045854">
        <property type="entry name" value="NO2/SO3_Rdtase_4Fe4S_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00612">
        <property type="entry name" value="ispG_gcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30454:SF0">
        <property type="entry name" value="4-HYDROXY-3-METHYLBUT-2-EN-1-YL DIPHOSPHATE SYNTHASE (FERREDOXIN), CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04551">
        <property type="entry name" value="GcpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26540">
        <property type="entry name" value="GcpE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037336">
        <property type="entry name" value="IspG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56014">
        <property type="entry name" value="Nitrite and sulphite reductase 4Fe-4S domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IspG TIM-barrel" evidence="14">
        <location>
            <begin position="97"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="IspG C-terminal" evidence="15">
        <location>
            <begin position="650"/>
            <end position="738"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00051119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00060620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00061554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00067018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00072132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00083306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF04551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF26540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0556909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="751" mass="83548" checksum="2A5CC902649FB7D2" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GHW8</accession>
    <name>A0A8T0GHW8_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G076400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GHW8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026913">
        <property type="entry name" value="METTL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026:SF27">
        <property type="entry name" value="METHYLTRANSFERASE FKBM DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32026">
        <property type="entry name" value="METHYLTRANSFERASE-LIKE PROTEIN 24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0559066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="340" mass="39056" checksum="839252DEA677C044" modified="2022-10-12" version="1">MTYFGDLQAAGRSASPRVYYFVIVCLLSYIILDFVLHHSGTSQCADLVFDAAKAKAERAERRSDAIDAMKEDLICGSVIGHLNSGPKLPVAKAWNQMKWIGAPARCKVKGHLIESLDEMNNFRRGFALKFVGDVEDKTMILPWLYGSKVDLNKRARRVYLDLGANDFHTSVQWFSRMYPCDFTEVHAFEVTPGLFRIPKPGFNEDTNWSPENPHSIRVKQQPQVPDWMVDRIKLYNTYVSDADGDNAINITKFIKQELKLTADDAVVVKMDIEGAEWPILQRWLLDPEMAEIIDELFVEIHYRHNTMLDFHWGQFSHSREEATRLIASLRAKGYFIHAWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GJ70</accession>
    <name>A0A8T0GJ70_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_10G016000</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GJ70"/>
    <dbReference type="OrthoDB" id="1932208at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd14016">
        <property type="entry name" value="STKc_CK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000222">
        <property type="entry name" value="casein kinase 1-like protein HD16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050235">
        <property type="entry name" value="CK1_Ser-Thr_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055900">
        <property type="entry name" value="DUF7477"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11909">
        <property type="entry name" value="CASEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24289">
        <property type="entry name" value="DUF7477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="191"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="72"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="83"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="140"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0558284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="756" mass="83287" checksum="9288159EF8DC55F8" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GK50</accession>
    <name>A0A8T0GK50_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7748 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_10G004600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GK50"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056650">
        <property type="entry name" value="DUF7748"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24928">
        <property type="entry name" value="DUF7748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7748" evidence="2">
        <location>
            <begin position="3"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0558098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="152" mass="16514" checksum="99528AB120D13913" modified="2022-10-12" version="1">MGKTKVKNQTGFPVSLKVYSSGIQTNLLRQPLGDGQEYTIRIDTNATYREYWCAANPGRNPQDVILSSDDCAEFSEVTLKADKADDGSYTIRWEGSKPRSSVTQAPASESPANANQPRPVNTNGPQGPPPTVHGAPRPGKQPRSQRSKCTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKD8</accession>
    <name>A0A8T0GKD8_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_10G143400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKD8"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641:SF19">
        <property type="entry name" value="NEPHROCYSTIN-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45641">
        <property type="entry name" value="TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13424">
        <property type="entry name" value="TPR_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="329"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0559971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="384" mass="43404" checksum="09EF1A393A404CB0" modified="2022-10-12" version="1">MEEKKNFADTELENEVGYFKEPTLRLKNAEMEVARCNEEGDMEKALHLAMQAILLKAIDRVDPRKTGEGDNDMTVTTIMAIAKAMIQRGDPKCVNYLQRALLINHELHGPDHDSNFPIHEGFGDFYMNLGDSRAFYKEKQTLKSKDASIGINAKKIENEYDDYKKAMEEYATAYEKIAGSGNKTIAFQSGGKLDSRMGNMFSKAAKVQSRQGNDKEAAIIYEKAIRCLENASKPNKAKLAQMYYELGVSYHKAKQYSNSINACKSAIAYVNGEKKEGEKDSQEPLLLLIKKQQAISFYDGNEVENAKAMFEELMALQRKEYGGSSIIVAETLKYLGDVHVALKDKPQAEKFYSRALHILKKRLGPTDQTVKQLEQYTKQLNLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GKI3</accession>
    <name>A0A8T0GKI3_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G050500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein disulfide isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0558744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GKI3"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003756">
        <property type="term" value="F:protein disulfide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034976">
        <property type="term" value="P:response to endoplasmic reticulum stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000107">
        <property type="entry name" value="Protein disulfide-isomerase 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929">
        <property type="entry name" value="PROTEIN DISULFIDE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18929:SF218">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE 5-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13848">
        <property type="entry name" value="Thioredoxin_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00421">
        <property type="entry name" value="THIOREDOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="107"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="494"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0558744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="523" mass="57915" checksum="3356A80672B49298" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMH4</accession>
    <name>A0A8T0GMH4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amino acid transporter transmembrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_10G103200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMH4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013057">
        <property type="entry name" value="AA_transpt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01490">
        <property type="entry name" value="Aa_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Amino acid transporter transmembrane" evidence="7">
        <location>
            <begin position="3"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0559419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="164" mass="17756" checksum="C3BE1EC52E7AFF95" modified="2022-10-12" version="1">MVEFFSGVGNILGAYGGHGITIEILETMKRPSAYKSVNLAVFFYALLVTSPSSVAVYWSAADILLKQSNSFAVLPSSGWQTLAIATIIALQVSTTCHDLPCSNIVELFYIVRDSMVQIQSDFCIVGPSELPVDGIVHYVLQTLAFLQVLALCILLVLVLLIVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GMX0</accession>
    <name>A0A8T0GMX0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homeobox domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_10G115400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 2 3">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GMX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00086">
        <property type="entry name" value="homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001356">
        <property type="entry name" value="HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044977">
        <property type="entry name" value="RLT1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36968:SF5">
        <property type="entry name" value="HOMEOBOX-DDT DOMAIN PROTEIN RLT2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00046">
        <property type="entry name" value="Homeodomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00389">
        <property type="entry name" value="HOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50071">
        <property type="entry name" value="HOMEOBOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="2 3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Homeobox" evidence="5">
        <location>
            <begin position="19"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="Homeobox" evidence="2">
        <location>
            <begin position="21"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="78"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="210"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="93"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0559579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="239" mass="26867" checksum="F000BE3003169D0F" modified="2022-10-12" version="1">MASNEGSPVMSPKNPSPEKRKGISRKKKSASQTEVLEKAYAVEKYPCEATRTRLCRDLDLTEKQLQIWFTHRRYKDRRDGIDDEELISKARGSKHDHVQHEDPRSSKKREIDLNSREGEDSEDGHPARVLAEEHYDEEFMGDNPNGLDVSGGDEEPPKPRPKLKPGRKPGTRVPRDPNMPPRKPGPKPKMDAAAAAERVAILAIERQLGGPLREDGPPLGFEFDPLPPDAFQQPAWTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNA0</accession>
    <name>A0A8T0GNA0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="5 10">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">KC19_10G123700</name>
        <name evidence="12" type="ORF">KC19_10G123800</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the class I fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 10"/>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GNA0"/>
    <dbReference type="OrthoDB" id="36455at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00948">
        <property type="entry name" value="FBP_aldolase_I_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000068">
        <property type="entry name" value="Fructose-bisphosphate aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029768">
        <property type="entry name" value="Aldolase_I_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000741">
        <property type="entry name" value="FBA_I"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF033379">
        <property type="entry name" value="FrucBisAld_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11627">
        <property type="entry name" value="FRUCTOSE-BISPHOSPHATE ALDOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00274">
        <property type="entry name" value="Glycolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51569">
        <property type="entry name" value="Aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00158">
        <property type="entry name" value="ALDOLASE_CLASS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0704">Schiff base</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG0559693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG0559694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="356" mass="38447" checksum="2BA0C36F5CB5F114" modified="2022-10-12" version="1">MAPYAGKYADELVATAKYIATPGKGILAADESTGTIGKRLSSIKVENVEANRQALRELLFTTPGVHEFLSGVILFEETLYQKTLDGKPFVEVMKEGGVIPGIKVDKGTIDLWGTNGETTTQGFDDLHKRCATYYNAGARFAKWRAVLKIGELEPTQLAIDQNAQGLARYAIICQENGLVPIVEPEILVDGSQSIEKCAEVTEKVLAACYKALNDQHVLLEGTLLKPNMVTPGSDAKKVSPEEVAKYTVRTLQRTVPPAVPGVVFLSGGQSEEEATQNLNAMNALKATKPWTLSFSFGRALQATVLKTWGGKKENVEAAQKALYVRAKANSEATLGTYGGSASDVGTESLHVKDYKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GNB0</accession>
    <name>A0A8T0GNB0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1-phosphatidylinositol 4-kinase</fullName>
            <ecNumber evidence="3">2.7.1.67</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_9G032800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.67" evidence="3"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10264149at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004430">
        <property type="term" value="F:1-phosphatidylinositol 4-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05167">
        <property type="entry name" value="PI4Kc_III_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000012">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000012">
        <property type="entry name" value="Phosphatidylinositol 4-kinase alpha 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045495">
        <property type="entry name" value="PI4K_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF15">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 4-KINASE ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19274">
        <property type="entry name" value="PI4K_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIK helical" evidence="9">
        <location>
            <begin position="1517"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="1770"/>
            <end position="2048"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="243"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1434"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="1450"/>
            <end position="1461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0561046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="2064" mass="227246" checksum="460DD61A03DDBB45" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GQI6</accession>
    <name>A0A8T0GQI6_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_10G189800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0560559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GQI6"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0560559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="121" mass="13364" checksum="900C9B2AC160060F" modified="2022-10-12" version="1">MTTKRNWRQEKVMAASEDVGERVNQADGEGIRARGVQRMVVREREIQMSESRQTEQKSESGSQASSERKKGRPRESVTRGRGRGRRSGPPSLPPSLAATEARPTSSGNTGTHNPPSRTHPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GRN9</accession>
    <name>A0A8T0GRN9_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein kinase ATM</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">KC19_9G018200</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0560844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05171">
        <property type="entry name" value="PIKKc_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000015">
        <property type="entry name" value="Serine/threonine-protein kinase ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.1010.10:FF:000023">
        <property type="entry name" value="Serine/threonine-protein kinase ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038980">
        <property type="entry name" value="ATM_plant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057445">
        <property type="entry name" value="ATM_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003152">
        <property type="entry name" value="FATC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044107">
        <property type="entry name" value="PIKKc_ATM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37079:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25360">
        <property type="entry name" value="TPR_ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01343">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00915">
        <property type="entry name" value="PI3_4_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0539">Nucleus</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="16">
        <location>
            <begin position="1925"/>
            <end position="2585"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="15">
        <location>
            <begin position="2691"/>
            <end position="3003"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="17">
        <location>
            <begin position="3018"/>
            <end position="3050"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1874"/>
            <end position="1900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2975"/>
            <end position="2997"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00073111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KAG0560844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="3050" mass="343426" checksum="94FBF75A75F1E175" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS61</accession>
    <name>A0A8T0GS61_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">KC19_10G129300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026431">
        <property type="protein sequence ID" value="KAG0559792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 10"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006952">
        <property type="term" value="P:defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.430">
        <property type="entry name" value="Helical domain of apoptotic protease-activating factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="entry name" value="Toll/interleukin-1 receptor homology (TIR) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042197">
        <property type="entry name" value="Apaf_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050715">
        <property type="entry name" value="LRR-SigEffector_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055414">
        <property type="entry name" value="LRR_R13L4/SHOC2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058192">
        <property type="entry name" value="WHD_ROQ1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752:SF195">
        <property type="entry name" value="LEUCINE-RICH REPEAT (LRR) FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45752">
        <property type="entry name" value="LEUCINE-RICH REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23598">
        <property type="entry name" value="LRR_14"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01582">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23282">
        <property type="entry name" value="WHD_ROQ1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00364">
        <property type="entry name" value="DISEASERSIST"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="16"/>
    </dbReference>
    <dbReference type="SMART" id="SM00255">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="Toll/Interleukin receptor TIR domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="TIR" evidence="4">
        <location>
            <begin position="28"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1805"/>
            <end position="1824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG0559792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1834" mass="209211" checksum="8874E815FC034AC3" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GS77</accession>
    <name>A0A8T0GS77_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="4 11">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ADP-glucose pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">KC19_9G065300</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Heterotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Plastid</location>
            <location evidence="11">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="4 11"/>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GS77"/>
    <dbReference type="OrthoDB" id="1733332at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02508">
        <property type="entry name" value="ADP_Glucose_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04651">
        <property type="entry name" value="LbH_G1P_AT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.550.10:FF:000030">
        <property type="entry name" value="Glucose-1-phosphate adenylyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002772">
        <property type="entry name" value="PRK02862.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523:SF12">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE LARGE SUBUNIT 1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="GLUCOSE-1-PHOSPHATE ADENYLYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25247">
        <property type="entry name" value="LbH_GLGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="Trimeric LpxA-like enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-0934">Plastid</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 11" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Nucleotidyl transferase" evidence="12">
        <location>
            <begin position="103"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG0561447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="531" mass="58266" checksum="E9B67D774BE5D7D7" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GUD5</accession>
    <name>A0A8T0GUD5_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">KC19_9G153200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0562523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GUD5"/>
    <dbReference type="OrthoDB" id="270584at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002067">
        <property type="entry name" value="MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24089">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00926">
        <property type="entry name" value="MITOCARRIER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="124"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="222"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="6">
        <location>
            <begin position="316"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="398"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG0562523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="427" mass="46231" checksum="2DFF28DC980A7948" modified="2022-10-12" version="1">MGGHGTESLASCAAARATPAGLQRPGRQKLYAESVTHMPAVVCSTSERTAELVRRRKGTAGVASVAKAMAPASEFGFRTLIPTEAEFREVLGLVKEEVEEDVAKEEKKKGRKIVLKGFKVKVGNASLRRLISGAIAGAVSRTAVAPLETIRTHLMVGSGGEKMSVAGMFQTIMQRDGWQGLFRGNGVNVLRVAPSKAIEMFAYDSVRTFLTPRNGEPSRIPLPVPVSLVAGAAAGVSSTITMYPLELLKTRLTVEHGMYNNLLHAFVKIVKEEGPMELYRGLLPSLIGVIPYAAINYCSYDTLRKTYRRLAKREDIGNIETLLMGSIAGAVASTVSFPLEVARKQMQVGNIGGRQVYNNVFHALSSIVKEQGPQGLYRGLGPSCIKIIPAAGISFMCYEACKRILVEEQAKLVEEEKEKESAEEMKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GWX0</accession>
    <name>A0A8T0GWX0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Secreted protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_9G062700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026430">
        <property type="protein sequence ID" value="KAG0561412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GWX0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035883020" description="Secreted protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0561412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="73" mass="8158" checksum="0C291B2C014FD7B4" modified="2022-10-12" version="1">MPELALSLGFLVCILPKCLCRLLELRPGLALSEAQAASSTFDRIMIDDRYLASNHPLVSSYFFSFSFSVKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZ78</accession>
    <name>A0A8T0GZ78_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mediator complex subunit 9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G105200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZ78"/>
    <dbReference type="OrthoDB" id="779656at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038790">
        <property type="entry name" value="Med9_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37188">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37188:SF1">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="114" mass="12982" checksum="5FF7E328DB9BB4F1" modified="2022-10-12" version="1">MSWSQAQSQGQGGWQPHPFQTQAFDFHLVPVIEALADAVEGGARDQQVDELVHELATRFQKAEQILNSFGSNATEKDVTTQKRTLEDHRNKLEERRALLVKYKSMVDRIYPADT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0GZU9</accession>
    <name>A0A8T0GZU9_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G107200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0GZU9"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0564393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="72" mass="8056" checksum="E261A6ECDD741FDE" modified="2022-10-12" version="1">MYLQQSPRWRAQLKMVSRRYNSFAQKLSTIGVSLMQMHLQRAVDLFLVSAAIILPSFSTERGSYGGNGMSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H3V7</accession>
    <name>A0A8T0H3V7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TF-B3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">KC19_8G139400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H3V7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd10017">
        <property type="entry name" value="B3_DNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.330.10">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003340">
        <property type="entry name" value="B3_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015300">
        <property type="entry name" value="DNA-bd_pseudobarrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044837">
        <property type="entry name" value="REM16-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391:SF4">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS03G0184500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31391">
        <property type="entry name" value="B3 DOMAIN-CONTAINING PROTEIN OS11G0197600-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02362">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01019">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101936">
        <property type="entry name" value="DNA-binding pseudobarrel domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50863">
        <property type="entry name" value="B3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TF-B3" evidence="6">
        <location>
            <begin position="124"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="37"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="267"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="38"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG0564778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="398" mass="44520" checksum="F9F6DAE6A0A8050C" modified="2022-10-12" version="1">MAVERSDYEESRKQRVEENKRRMQELGIMELSKDLKGSKQKNVVRKPLKRKIDDAGGESRRSSRVAAKPAVTYKDQLDLLPGMRARCGTRERVGLGRRYVSDLSRRAAYEAAEEAFKDIRNPGFVKAMLHSHVTSCFWLGLPNRFCQEHMPLEETTFILEDDKGKEWECVYLAHKTGMSGGWRGFSLDHELVDGDSCIFELVSPLRFKVHFFRCDEEDGGPEEVDDKKTGVNVAGKDTKTEKKVGKVATKKKKAGFYKGKKSRKSSSKKLKLEDGEEDNEDSDDDDDDDEGDDYAPRVSKQDADTNVAGPSRASRRQVVKKEADAGEGLVVASKNKDKESGKLNGKELDDLIELESGEDEDEDKDALKSPLVTKTIQGGSGSLSSGRATRNSLRRSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H561</accession>
    <name>A0A8T0H561_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="18">Peptidylprolyl isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">KC19_8G197900</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins. May also function as a chaperone, playing a role in intracellular transport of proteins. May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.27"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="19">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H561"/>
    <dbReference type="OrthoDB" id="30774at2759"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071013">
        <property type="term" value="C:catalytic step 2 spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01923">
        <property type="entry name" value="cyclophilin_RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16663">
        <property type="entry name" value="RING-Ubox_PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000079">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.100.10:FF:000014">
        <property type="entry name" value="Peptidyl-prolyl cis-trans isomerase cyp65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026951">
        <property type="entry name" value="PPIL2_U-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625:SF1">
        <property type="entry name" value="RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04641">
        <property type="entry name" value="Rtf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0143">Chaperone</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0697">Rotamase</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="U-box" evidence="15">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="14">
        <location>
            <begin position="352"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="511"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG0565534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="18">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="603" mass="66861" checksum="ADE1ACE25EC8874E" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5Q0</accession>
    <name>A0A8T0H5Q0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Choline transporter-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">KC19_7G078800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Choline transporter.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the CTL (choline transporter-like) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5Q0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007603">
        <property type="entry name" value="Choline_transptr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12385:SF14">
        <property type="entry name" value="CHOLINE TRANSPORTER-LIKE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04515">
        <property type="entry name" value="Choline_transpo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="426"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="488"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="539"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="646"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU368066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG0566643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="763" mass="82714" checksum="8C80D697E08CE90C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H5Z4</accession>
    <name>A0A8T0H5Z4_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_7G127900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0567346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H5Z4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0567346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="67" mass="7589" checksum="71ED30C150BEA0AA" modified="2022-10-12" version="1">MTLYHTVNKMVSPKWAQQDELGKMGSTRWSQQNGLNNTNSANWAPTQTEQNGLQDEKLRKLGKERGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H600</accession>
    <name>A0A8T0H600_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">S-adenosylmethionine synthase</fullName>
            <ecNumber evidence="16">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">KC19_8G118100</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">R40</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the formation of S-adenosylmethionine from methionine and ATP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>L-methionine + ATP + H2O = S-adenosyl-L-methionine + phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="16">Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="16">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="16">Binds 2 divalent ions per subunit. The metal ions interact primarily with the substrate. Can utilize magnesium, manganese or cobalt (in vitro).</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 16">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 17">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="16"/>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0564532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H600"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18079">
        <property type="entry name" value="S-AdoMet_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000001">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000003">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.300.10:FF:000004">
        <property type="entry name" value="S-adenosylmethionine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="S-ADENOSYLMETHIONINE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="S-adenosylmethionine synthetase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0170">Cobalt</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="12 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 16" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="13 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 16" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-adenosylmethionine synthetase N-terminal" evidence="18">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase central" evidence="19">
        <location>
            <begin position="130"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="S-adenosylmethionine synthetase C-terminal" evidence="20">
        <location>
            <begin position="253"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU000541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG0564532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="406" mass="44697" checksum="C13DFFCF9F05B93F" modified="2022-10-12" version="1">MWFIEVVCRGYVQMETFLFTSESVNEGHPDKLCDQVSDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKAVVDYEKIVRDTCREIGFVSDDVGLDADKCKVLMNLEAQSPDIAQGVHGHFTKKPEDIGAGDQGHMFGYATDETEELMPLTHVLATKLGAKLTEVRKNGTCAWLRPDGKTQVTVEYKNEGGAMVPLRVHTVLISTQHDETVTNDQIAADLKKHVIGPVIPEKYMDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVAAGMARRCIVQVSYAIGVPEPLSVFVDTYGTGKIHDSEILKIVKENFDFRPGMMCINLDLKRGGNKRFQKTAAYGHFGREDPDFTWEIVKPLKWEHLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H6E7</accession>
    <name>A0A8T0H6E7_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ubiquitinyl hydrolase 1</fullName>
            <ecNumber evidence="3">3.4.19.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">KC19_7G095800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">R40</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12 13">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="3"/>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H6E7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009867">
        <property type="term" value="P:jasmonic acid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010078">
        <property type="term" value="P:maintenance of root meristem identity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031647">
        <property type="term" value="P:regulation of protein stability"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2000280">
        <property type="term" value="P:regulation of root development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02659">
        <property type="entry name" value="peptidase_C19C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.210.10:FF:000005">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000034">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.20.90:FF:000050">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.10:FF:000002">
        <property type="entry name" value="Ubiquitin carboxyl-terminal hydrolase 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024729">
        <property type="entry name" value="USP7_ICP0-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029346">
        <property type="entry name" value="USP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006:SF644">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14533">
        <property type="entry name" value="USP7_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12436">
        <property type="entry name" value="USP7_ICP0_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00972">
        <property type="entry name" value="USP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="5" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="MATH" evidence="8">
        <location>
            <begin position="34"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="USP" evidence="9">
        <location>
            <begin position="178"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG0566893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1095" mass="128044" checksum="C650E5377E9A0590" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2025-04-02" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H727</accession>
    <name>A0A8T0H727_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">OCEL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">KC19_7G044400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026428">
        <property type="protein sequence ID" value="KAG0566184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010844">
        <property type="entry name" value="Occludin_ELL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38372">
        <property type="entry name" value="DENTIN SIALOPHOSPHOPROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38372:SF2">
        <property type="entry name" value="DENTIN SIALOPHOSPHOPROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07303">
        <property type="entry name" value="Occludin_ELL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144292">
        <property type="entry name" value="occludin/ELL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51980">
        <property type="entry name" value="OCEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OCEL" evidence="2">
        <location>
            <begin position="1461"/>
            <end position="1567"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="289"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="416"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="318"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="330"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="504"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="556"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="591"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="634"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="654"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="882"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="984"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1034"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1088"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1100"/>
            <end position="1118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1228"/>
            <end position="1242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1324"/>
            <end position="1338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1396"/>
            <end position="1411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG0566184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1589" mass="169513" checksum="4AF23A3E0236765F" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0H8S7</accession>
    <name>A0A8T0H8S7_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_8G193100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026429">
        <property type="protein sequence ID" value="KAG0565472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0H8S7"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0565472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="106" mass="11410" checksum="72DA71E319E5EFE4" modified="2022-10-12" version="1">MSHGGTLVLLYKSDQGYVTVSLKRLTNDTGVVGQTAPLSASLFAPKWTSLMRGALACSETARQLLSMILALFSLCKKLVSHTLITPMQIAAASNLCAVLIIGWAWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HCT4</accession>
    <name>A0A8T0HCT4_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">KC19_6G064100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HCT4"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03801">
        <property type="entry name" value="GT4_PimA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041693">
        <property type="entry name" value="Glyco_trans_4_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47778">
        <property type="entry name" value="BNAA05G14870D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47778:SF2">
        <property type="entry name" value="GLYCOSYL TRANSFERASE FAMILY 1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16994">
        <property type="entry name" value="Glyco_trans_4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase family 1" evidence="3">
        <location>
            <begin position="515"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="15"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG0569080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="671" mass="73723" checksum="57FC55953BC5DAAB" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HD38</accession>
    <name>A0A8T0HD38_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">KC19_6G004000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0568224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HD38"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG0568224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="114" mass="12975" checksum="1A67F9E800F696B1" modified="2022-10-12" version="1">MRHAPFRAESRTTSFVAVWVKGSSVSVICISDHLLYCFCMIRCSLPVSHYLQLCFSSTWSWRIVLVRKLCFTSKQSYLVCALQVIRVSCLDDLGLQSRGRRMLLSILLAPNQAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HE06</accession>
    <name>A0A8T0HE06_CERPU</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">KC19_6G134400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HE06"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG0570036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="123" mass="13992" checksum="A670B4EF5FD7E816" modified="2022-10-12" version="1" fragment="single">PQYLRRTLHLDVFNACHVGPRSLSKHSRAFNPKNHPFTTMTTSTSYKTLLQHSTPLIPMTILKPIPEPMRHRKARARTSTQSRKTAQKTTTQPTTAQQHEPELQPRHSFTRTTAFTPTPPEAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HEY5</accession>
    <name>A0A8T0HEY5_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G074200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HEY5"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051165">
        <property type="entry name" value="Multifunctional_ANK_Repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026961">
        <property type="entry name" value="PGG_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24123:SF33">
        <property type="entry name" value="PROTEIN HOS4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13962">
        <property type="entry name" value="PGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="9"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="665"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="706"/>
            <end position="731"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="743"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="34"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="181"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="218"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="495"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="PGG" evidence="5">
        <location>
            <begin position="607"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF13962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="800" mass="88867" checksum="31B5A88F6A3D22CC" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HG37</accession>
    <name>A0A8T0HG37_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Importin N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">KC19_6G101400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0569597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HG37"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005635">
        <property type="term" value="C:nuclear envelope"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005049">
        <property type="term" value="F:nuclear export signal receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031267">
        <property type="term" value="F:small GTPase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006611">
        <property type="term" value="P:protein export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001494">
        <property type="entry name" value="Importin-beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997:SF29">
        <property type="entry name" value="ARM REPEAT SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10997">
        <property type="entry name" value="IMPORTIN-7, 8, 11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03810">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00913">
        <property type="entry name" value="IBN_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50166">
        <property type="entry name" value="IMPORTIN_B_NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Importin N-terminal" evidence="5">
        <location>
            <begin position="55"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1015"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="447"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1022"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG0569597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000822688"/>
        </source>
    </evidence>
    <sequence length="1142" mass="126372" checksum="3DB1C282421ABD3C" modified="2022-10-12" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2022-10-12" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A8T0HGE0</accession>
    <name>A0A8T0HGE0_CERPU</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">KC19_6G157800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ceratodon purpureus</name>
        <name type="common">Fire moss</name>
        <name type="synonym">Dicranum purpureum</name>
        <dbReference type="NCBI Taxonomy" id="3225"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Streptophyta</taxon>
            <taxon>Embryophyta</taxon>
            <taxon>Bryophyta</taxon>
            <taxon>Bryophytina</taxon>
            <taxon>Bryopsida</taxon>
            <taxon>Dicranidae</taxon>
            <taxon>Pseudoditrichales</taxon>
            <taxon>Ditrichaceae</taxon>
            <taxon>Ceratodon</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2020-06" db="EMBL/GenBank/DDBJ databases">
            <title>WGS assembly of Ceratodon purpureus strain R40.</title>
            <authorList>
                <person name="Carey S.B."/>
                <person name="Jenkins J."/>
                <person name="Shu S."/>
                <person name="Lovell J.T."/>
                <person name="Sreedasyam A."/>
                <person name="Maumus F."/>
                <person name="Tiley G.P."/>
                <person name="Fernandez-Pozo N."/>
                <person name="Barry K."/>
                <person name="Chen C."/>
                <person name="Wang M."/>
                <person name="Lipzen A."/>
                <person name="Daum C."/>
                <person name="Saski C.A."/>
                <person name="Payton A.C."/>
                <person name="Mcbreen J.C."/>
                <person name="Conrad R.E."/>
                <person name="Kollar L.M."/>
                <person name="Olsson S."/>
                <person name="Huttunen S."/>
                <person name="Landis J.B."/>
                <person name="Wickett N.J."/>
                <person name="Johnson M.G."/>
                <person name="Rensing S.A."/>
                <person name="Grimwood J."/>
                <person name="Schmutz J."/>
                <person name="Mcdaniel S.F."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">R40</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="CM026427">
        <property type="protein sequence ID" value="KAG0570380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A8T0HGE0"/>
    <dbReference type="Proteomes" id="UP000822688">
        <property type="component" value="Chromosome 6"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010277">
        <property type="term" value="F:chlorophyllide a oxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.380.10">
        <property type="entry name" value="Naphthalene 1,2-dioxygenase Alpha Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="entry name" value="Rieske [2Fe-2S] iron-sulphur domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050584">
        <property type="entry name" value="Cholesterol_7-desaturase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013626">
        <property type="entry name" value="PaO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266:SF32">
        <property type="entry name" value="CHOLESTEROL 7-DESATURASE NVD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21266">
        <property type="entry name" value="IRON-SULFUR DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08417">
        <property type="entry name" value="PaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="ISP domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0809">Transit peptide</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="509"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="domain" description="Rieske" evidence="16">
        <location>
            <begin position="118"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="34"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
      